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2. Update on the Management of Pediatric Psoriasis: An Italian Consensus

Author

Peris, Ketty, Fortina, Anna Belloni, Bianchi, Luca, Fabbrocini, Gabriella, Gisondi, Paolo, Balato, Anna, Bardazzi, Federico, Bernardini, Nicoletta, Bonamonte, Domenico, Bongiorno, Maria Rita, Buligan, Cinzia, Cusano, Francesco, Del Giudice, Maria Beatrice De Felici, El Hachem, May, Fargnoli, Maria Concetta, Gualdi, Giulio, Guarneri, Claudio, Hansel, Katharina, Malara, Giovanna, Mazzatenta, Carlo, Micali, Giuseppe, Narcisi, Alessandra, Neri, Iria, Oranges, Teresa, Panzone, Michele, Parodi, Aurora, Restano, Lucia, Simonetti, Oriana, Venturini, Marina, and Di Lernia, Vito

Published
2022
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6. Sequelae following infantile haemangiomas treated with propranolol

Author

Baselga, Eulalia, El Hachem, May, Diociaiuti, Andrea, Carnevale, Claudia, Downey, Camila, Roe, Esther, Mascaro, Patricia, Neri, Iria, Leuzzi, Miriam, Bernabeu-Wittel, José, Monserrat-García, Maria Teresa, Ortiz-Prieto, Alejandro, Torrelo, Antonio, Knopfel, Nicole, Vercellino, Nadia, Manunza, Francesca, Oranges, Teresa, Bassi, Andrea, Gonzalez-Enseñat, Maria Antonia, Vicente, Asunción, Gich, Ignasi, and Puig, Luis

Published
2021
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9. Dupilumab treatment of trichothiodystrophy in a child

Author

Magnaterra, Elisabetta, primary, Giovannini, Mattia, additional, Filippeschi, Cesare, additional, Pedaci, Fausto Andrea, additional, Tronconi, Greta, additional, Callea, Michele, additional, Ricci, Silvia, additional, Mori, Francesca, additional, Parpagnoli, Maria, additional, and Oranges, Teresa, additional

Published
2024
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16. Ultra-High Frequency UltraSound (UHFUS) Assessment of Barrier Function in Moderate-to-Severe Atopic Dermatitis during Dupilumab Treatment

Author

Dini, Valentina, primary, Iannone, Michela, additional, Michelucci, Alessandra, additional, Manzo Margiotta, Flavia, additional, Granieri, Giammarco, additional, Salvia, Giorgia, additional, Oranges, Teresa, additional, Janowska, Agata, additional, Morganti, Riccardo, additional, and Romanelli, Marco, additional

Published
2023
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18. Dermatological findings in Rubinstein-Taybi Syndrome

Author

CAMMARATA-SCALISI, Francisco, primary, DIOCIAIUTI, Andrea, additional, CÁRDENAS TADICH, Antonio, additional, SANDOVAL, Ximena, additional, ORANGES, Teresa, additional, FILIPPESCHI, Cesare, additional, ARAYA CASTILLO, Maykol, additional, WILLOUGHBY, Colin E., additional, CERRI, Amilcare, additional, GERVASINI, Cristina, additional, and CALLEA, Michele, additional

Published
2023
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19. COVID 19-associated chilblain-like acral lesions among children and adolescents: an Italian retrospective, multicenter study

Author

ROMITA, Paolo, primary, MARONESE, Carlo A., additional, DE MARCO, Aurora, additional, BALESTRI, Riccardo, additional, BELLONI FORTINA, Anna, additional, BRAZZELLI, Valeria, additional, COLONNA, Cristiana, additional, DI LERNIA, Vito, additional, EL HACHEM, May, additional, FABBROCINI, Gabriella, additional, FRASIN, Lucretia A., additional, GUARNERI, Claudio, additional, GUERRIERO, Cristina, additional, GUIDA, Stefania, additional, LOCATELLI, Andrea, additional, NERI, Iria, additional, OCCELLA, Corrado, additional, OFFIDANI, Annamaria, additional, ORANGES, Teresa, additional, PELLACANI, Giovanni, additional, STINCO, Giuseppe, additional, STINGENI, Luca, additional, BARBAGALLO, Tania, additional, CAMPANATI, Anna, additional, CANNAVÒ, Serafinella P., additional, CAROPPO, Francesca, additional, CAVALLI, Riccardo, additional, COSTANTINI, Alessio, additional, CUCCHIA, Rosa, additional, DIOCIAIUTI, Andrea, additional, FILIPPESCHI, Cesare, additional, FRANCOMANO, Mariangela, additional, GIANCRISTOFORO, Simona, additional, GIUFFRIDA, Roberta, additional, MARTINA, Emanuela, additional, MONZANI, Nicola A., additional, NAPPA, Paola, additional, PASTORINO, Carlotta, additional, PATRIZI, Annalisa, additional, PECCERILLO, Francesca, additional, PERIS, Ketty, additional, RECALCATI, Sebastiano, additional, RIZZOLI, Laura, additional, SIMONETTI, Oriana, additional, VASTARELLA, Maria, additional, VIRDI, Annalucia, additional, MARZANO, Angelo V., additional, and BONAMONTE, Domenico, additional

Published
2023
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20. Multiparametric Skin Assessment in a Monocentric Cohort of Systemic Sclerosis Patients: Is There a Role for Ultra-High Frequency Ultrasound?

Author

Di Battista, Marco, primary, Barsotti, Simone, additional, Vitali, Saverio, additional, Palma, Marco, additional, Granieri, Giammarco, additional, Oranges, Teresa, additional, Aringhieri, Giacomo, additional, Dini, Valentina, additional, Della Rossa, Alessandra, additional, Neri, Emanuele, additional, Romanelli, Marco, additional, and Mosca, Marta, additional

Published
2023
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21. Next generation sequencing panel target genes: possible diagnostic tool for ectodermal dysplasia related diseases

Author

CALLEA, Michele, primary, BELLACCHIO, Emanuele, additional, CAMMARATA SCALISI, Francisco, additional, EL FEGHALY, Jinia, additional, EL-GHANDOUR, Rabab K., additional, AVENDAÑO, Andrea, additional, YAVUZ, Yasemine, additional, DIOCIAIUTI, Andrea, additional, DIGILIO, Maria C., additional, DI STAZIO, Mariateresa, additional, NOVELLI, Antonio, additional, ORANGES, Teresa, additional, FILIPPESCHI, Cesare, additional, PISANESCHI, Elisa, additional, JILANI, Houweyda, additional, GIGOLA, Francesca, additional, WILLOUGHBY, Colin E., additional, and MORABITO, Antonino, additional

Published
2023
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24. Biological treatments for pediatric Netherton syndrome

Author

Pontone, Matteo, primary, Giovannini, Mattia, additional, Filippeschi, Cesare, additional, Oranges, Teresa, additional, Pedaci, Fausto Andrea, additional, Mori, Francesca, additional, Barni, Simona, additional, Barbati, Federica, additional, Consonni, Filippo, additional, Indolfi, Giuseppe, additional, Lodi, Lorenzo, additional, Azzari, Chiara, additional, Ricci, Silvia, additional, and Hovnanian, Alain, additional

Published
2022
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26. Complications

Author

Oranges, Teresa, primary, Dini, Valentina, additional, Chiricozzi, Andrea, additional, Panduri, Salvatore, additional, and Romanelli, Marco, additional

Published
2017
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27. The Association Between pH and Fluorescence as Noninvasive Diagnostic Tools in Chronic Wounds.

Author

Janowska, Agata, Davini, Giulia, Romanelli, Marco, Oranges, Teresa, Iannone, Michela, and Dini, Valentina

Abstract

MolecuLight i:X is a noninvasive, portable device that captures images, measures wound areas, and allows the evaluation of the bacterial environment in real time. The aim of the study was to correlate the different fluorescence (light green, red, cyan) and dark red–purple–black color areas with average pH values in these areas and with average wound bed score (WBS). During a 4-week period, we enrolled 43 adult patients (23 females and 20 males) with clinically infected and uninfected chronic ulcers. In our study, the mean age was 68 years old. The etiologies were 21 venous ulcers, 3 arterial ulcers, 4 vasculitis, 7 pyoderma gangrenosum, 7 traumatic ulcers, and 1 neoplastic ulcer. The average area was 16.92 cm2 and the average WBS was 9.17. A total of 16 ulcers (37%) were positive for clinical signs and symptoms of infection and 27 ulcers were negative (63%). Thirty-six ulcers emitted a single fluorescence: cyan (n = 13), red (n = 1), light green (n = 14), and dark red-purple–black (n = 8). Six wounds showed a double fluorescence area: red and cyan (n = 1) and cyan and light green (n = 5). One ulcer emitted a triple fluorescence area: red, cyan, and light green. Overall in 43 ulcers, we found 43 fluorescence and 8 dark red–purple–black color. We found significant data between pH and fluorescence. pH values on wound bed confirm in a noninvasive way the correlation between fluorescence and bacterial burden. Moreover, MolecuLight i:X is able to detect objectively the bacterial proliferation, in contrast with pH which cannot distinguish different types of bacteria. [ABSTRACT FROM AUTHOR]

Published
2023
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29. Ultra‐High Frequency Ultrasound in Melanoma Management

Author

Oranges, Teresa, primary, Janowska, Agata, additional, Scatena, Cristian, additional, Faita, Francesco, additional, Lascio, Nicole Di, additional, Izzetti, Rossana, additional, Fidanzi, Cristian, additional, Romanelli, Marco, additional, and Dini, Valentina, additional

Published
2022
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30. Fever and Challenging Cutaneous Mimicked-Urticaria Reaction to Amoxicillin-Clavulanate in two Children.

Author

Alberio, Antonino Maria Quintilio, Nuzzi, Giulia, Di Cicco, Maria, Peroni, Diego, Oranges, Teresa, and Baroncelli, Giampiero Igli

Subjects
DIAGNOSIS of fever, OTITIS media diagnosis, PHYSICAL diagnosis, CLAVULANIC acid, CETIRIZINE, FEVER, BETAMETHASONE, TREATMENT effectiveness, URTICARIA, SERUM sickness, BLOOD testing, URINALYSIS, AMOXICILLIN, ANTIBIOTICS, OTITIS media
Abstract

The article presents two pediatric cases (patients A and B) presenting with fever and pruritic urticaria-like rash after discontinuation of oral amoxicillin-clavulanate. Topics include the clinical manifestations, examination findings, and hospital course of the patients. Both children exhibited erythematous-edematous plaques with purple lesions, and patient A additionally had periorbital edema.

Published
2023
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34. A Unique Case of Primary Cutaneous Adenoid Cystic Carcinoma Associated with Aplasia Cutis Congenita in a Four-Year-Old Female: A Case Report

Author

Zulli, Andrea, primary, Martin, Alessandra, additional, Facchini, Flavio, additional, Coletta, Riccardo, additional, Tamburini, Angela, additional, Oranges, Teresa, additional, Filippeschi, Cesare, additional, Bassi, Andrea, additional, Buccoliero, Anna Maria, additional, and Morabito, Antonino, additional

Published
2022
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37. Ultra‐High Frequency Ultrasound in Melanoma Management: A New Combined Ultrasonographic–Histopathological Approach.

Author

Oranges, Teresa, Janowska, Agata, Scatena, Cristian, Faita, Francesco, Lascio, Nicole Di, Izzetti, Rossana, Fidanzi, Cristian, Romanelli, Marco, and Dini, Valentina

Subjects
ULTRASONIC imaging, GRAPHICAL user interfaces, SURGICAL margin, MELANOMA, DELAYED diagnosis, FUJIFILM digital cameras
Abstract

Objectives: The main aim of this study is to evaluate the correspondence between the ultrasonographic thickness and the Breslow thickness in melanoma using ultra‐high frequency ultrasound and the intra‐ and inter‐operator repeatability in the ultrasonographic measurements of melanoma depth. Moreover, we propose a new protocol based on a combined ultrasonographic–histopathological approach. Methods: We analyzed 27 melanomas in a population consisted of 27 patients (mean age 57.6 years, 51.8% males), who came at the Department of Dermatology (University of Pisa, Pisa, Italy) from April 2016 to March 2018 and had an ultrasonographic examination of a suspected lesion before the surgical removal using ultra‐high frequency ultrasound (Vevo®MD, Fujifilm, Visualsonics, Toronto, Canada; 70 MHz probe). B‐mode images were analyzed by two skilled and blinded operators, and the maximum depth of the lesions was measured using a dedicated graphical user interface developed in Matlab R2016b (MathWorks Inc., Natick, MA), to obtain repetitive measurements. Results: All melanomas appeared as band‐like or oval/fusiform shaped hypoechoic inhomogeneous lesions. We observed an excellent agreement between the Breslow thickness of melanomas and the ultrasonographic thickness, as well as a reduced intra‐ and inter‐operator variability in the ultrasonographic measurements of melanoma depth. Conclusions: We propose a ultrasonographic–histopathological protocol which may help clinicians to reduce the diagnostic delay, improve prognosis and survival rates, perform a surgical excision with negative margins, and reduce the variability in the assessment of Breslow thickness. [ABSTRACT FROM AUTHOR]

Published
2023
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38. Prognostic Indicators of Wound Healing in Atypical Wounds: A Case Series.

Author

Janowska, Agata, Romanelli, Marco, Oranges, Teresa, Davini, Giulia, Iannone, Michela, and Dini, Valentina

Abstract

Healing rate is the most accurate method to predict healing; however, there are no data in atypical ulcers. We retrospectively analyzed clinical features, associated comorbidities, and therapies of 159 patients with atypical ulcers. In a subgroup of 59 patients, we analyzed the areas, perimeters, and the healing rate (mm/d) as prognostic indicators of wound healing. Atypical ulcers were more frequent among women (n = 98) with an average age of 76 years. Confirmed by biopsy, the etiologies were as follows: inflammatory diseases (38%), neoplastic ulcers (29%), vasculitis (21%), drug-induced ulcers (7%), and infectious ulcers (4%). Systemic therapies were applied based on the different etiologies. Wound bed preparation principles guided the local treatment. The average reduction of the area during the observation interval was 36%, while the average reduction in the perimeter was 41%. Overall, 51 ulcers showed a reduction in wound size and 8 ulcers showed an increase. Neoplastic ulcers were the group with the fastest healing rate, with an average speed of 0.24 mm/d. The slowest healing occurred in the inflammatory group with an average healing rate of 0.032 mm/d. The initial area and perimeters influenced wound healing; however, ulcer etiology and comorbidities significantly altered the healing rate. [ABSTRACT FROM AUTHOR]

Published
2022
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42. Wound Management Strategy for Treatment of Localized Cutaneous Leishmaniasis Using the TIME Framework

Author

Iannone, Michela, Oranges, Teresa, Dini, Valentina, Romanelli, Marco, and Agata Janowska

Subjects
Adult, Anti-Infective Agents, Cryotherapy, Paromomycin, Humans, Leishmaniasis, Cutaneous, Female, Anti-Bacterial Agents
Abstract

The current drugs available for the treatment of cutaneous leishmaniasis (CL) often cause several adverse events, and the risk-benefit ratio is low due to the risk of severe complications. Current treatment recommendations are based on data from areas endemic for leishmaniasis and are not always perfectly applicable, especially in cases of imported CL. Thus, it is crucial to assess the level of severity in each case to provide the most appropriate treatment modality. The World Health Organization recommends simple wound care (with unspecified strategies) or local therapy as first-line treatment. Systemic treatments should be reserved for selected patients. Additionally, there is little evidence in the literature regarding local treatments, such as paromomycin ointments, imiquimod, local infiltration with antimonials, and physical treatments such as cryotherapy or thermotherapy.The authors report the use of the tissue debridement, infection/inflammation management, moisture balance, and edge assessment (TIME) model of wound bed preparation in a case of localized ulcerated CL.A 32-year-old female developed ulcerated nodules at the sites of insect bites that occurred during a trip to Columbia and was diagnosed with localized CL. Wound management included daily wound bed cleansing, surgical debridement, and antimicrobial and secondary polyurethane foam dressings. The lesions completely healed in 30 days.In the present case, the TIME approach simplified the local management of ulcerated CL, thereby improving both the healing process and cosmetic outcome. Further studies with a placebo-controlled group will be necessary to confirm the data.

Published
2021

47. Case Report and Review of the Literature: Bullous Skin Eruption After the Booster-Dose of Influenza Vaccine in a Pediatric Patient With Polymorphic Maculopapular Cutaneous Mastocytosis

Author

Sarcina, Davide, primary, Giovannini, Mattia, additional, Oranges, Teresa, additional, Barni, Simona, additional, Pedaci, Fausto Andrea, additional, Liccioli, Giulia, additional, Canessa, Clementina, additional, Sarti, Lucrezia, additional, Lodi, Lorenzo, additional, Filippeschi, Cesare, additional, Azzari, Chiara, additional, Ricci, Silvia, additional, and Mori, Francesca, additional

Published
2021
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50. Netherton Syndrome in Children: Management and Future Perspectives

Author

Barbati, Federica, primary, Giovannini, Mattia, additional, Oranges, Teresa, additional, Lodi, Lorenzo, additional, Barni, Simona, additional, Novembre, Elio, additional, Baldo, Ermanno, additional, Cristofolini, Mario, additional, Stagi, Stefano, additional, Ricci, Silvia, additional, Mori, Francesca, additional, Filippeschi, Cesare, additional, Azzari, Chiara, additional, and Indolfi, Giuseppe, additional

Published
2021
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