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Advanced experiments using THz pump and X-ray probe pulses at modern free-electron lasers (FELs) like the European X-ray FEL require a frequency-tunable, high-power, narrow-band THz source maintaining the repetition rate and pulse structure of the X-ray pulses. This paper reports the first results from a THz source, that is based on a single-pass high-gain THz FEL operating with a central wavelength of 100 micrometers. The THz FEL prototype is currently in operation at the Photo Injector Test facility at DESY in Zeuthen (PITZ) and uses the same type of electron source as the European XFEL photo injector. A self-amplified spontaneous emission (SASE) FEL was envisioned as the main mechanism for generating the THz pulses. Although the THz FEL at PITZ is supposed to use the same mechanism as at X-ray facilities, it cannot be considered as a simple scaling of the radiation wavelength because there is a large difference in the number of electrons per radiation wavelength, which is five orders of magnitude higher for the THz case. The bunching factor arising from the electron beam current profile contributes strongly to the initial spontaneous emission starting the FEL process. Proof-of-principle experiments were done at PITZ using an LCLS-I undulator to generate the first high-power, high-repetition-rate single-pass THz FEL radiation. Electron bunches with a beam energy of ~17 MeV and a bunch charge of up to several nC are used to generate THz pulses with a pulse energy of several tens of microjoules. For example, for an electron beam with a charge of ~2.4 nC, more than 100 microjoules were generated at a central wavelength of 100 micrometers. The narrowband spectrum was also demonstrated by spectral measurements. These proof-of-principle experiments pave the way for a tunable, high-repetition-rate THz source providing pulses with energies in the millijoule range., Comment: (unpublished) for submission to PRAB

Photoinjectors are the main high brightness electron sources for X-ray free electron lasers (XFEL). Photoinjector emittance reduction is one of the key knobs for improving XFEL lasing, so precise emittance measurement is critical. It's well known that rms emittance is very sensitive to low intensity tails of particle distributions in the phase space, whose measurement depend on the signal to noise ratio (SNR) and image processing procedures. Such sensitivities make the interpretations of beam transverse brightness challenging, leading to different emittance definitions to reduce the impact of tail particles. In this paper, transverse phase space is analyzed in action and phase coordinates for both analytical models and experiments, which give a more intuitive way to calculate the beam core brightness.

Slice energy spread is one of the key parameters in free electron laser optimizations, but its accurate measurement is not straightforward. Two recent studies from high energy ($>$100 MeV) photoinjectors at SwissFEL and European XFEL have reported much higher slice energy spread than expected at their XFEL working points (200 - 250 pC). In this paper, a new method for measuring slice energy spread at a lower beam energy ($\sim$20 MeV) is proposed and demonstrated at the PhotoInjector Test facility at DESY Zeuthen (PITZ), and the results for 250 pC and 500 pC are much lower than those measured at high energy injectors.

An essential part for the accurate classification of electrocardiogram (ECG) signals is the extraction of informative yet general features, which are able to discriminate diseases. Cardiovascular abnormalities manifest themselves in features on different time scales: small scale morphological features, such as missing P-waves, as well as rhythmical features apparent on heart rate scales. For this reason we incorporate a variant of the complex wavelet transform, called a scatter transform, in a deep residual neural network (ResNet). The former has the advantage of being derived from theory, making it well behaved under certain transformations of the input. The latter has proven useful in ECG classification, allowing feature extraction and classification to be learned in an end-to-end manner. Through the incorporation of trainable layers in between scatter transforms, the model gains the ability to combine information from different channels, yielding more informative features for the classification task and adapting them to the specific domain. For evaluation, we submitted our model in the official phase in the PhysioNet/Computing in Cardiology Challenge 2020. Our (Team Triage) approach achieved a challenge validation score of 0.640, and full test score of 0.485, placing us 4th out of 41 in the official ranking.

Over the last decades, photoreceptive proteins were extensively studied with biophysical methods to gain a fundamental understanding of their working mechanisms and further guide the development of optogenetic tools from them. Time-resolved infrared (IR) spectroscopy is one of the key methods to access their functional non-equilibrium processes with high temporal resolution, but has the major drawback that experimental data is usually highly complex. Linking the spectral response to specific molecular events is a major obstacle. Here, we investigate a cyanobacteriochrome (CBCR) photoreceptor with a combined approach of transient absorption spectroscopy in the Visible and IR spectral regions. We obtain kinetic information in both spectral regions by analysis with two different fitting methods, global multiexponential fitting and lifetime analysis. We investigate the ground state dynamics that follow photoexcitation in both directions of the bi-stable photocycle (Pr* and Pg*) in the nanosecond and microsecond time regime. We find two ground state intermediates associated with the decay of Pr* and four with Pg* and report the macroscopic time constants of their interconversions. One of these processes is assigned to a structural change in the protein backbone. At later delay times, the spectroscopic responses are stretched out in time, an effect that can be better described by the lifetime analysis than the global fit. We ascribe it to the intrinsic ruggedness of the free energy landscape of proteins., Comment: regular article 12 pages 7 figures and 2 tables

In state of the art photoinjector electron sources, thermal emittance from photoemission dominates the final injector emittance. Therefore, low thermal emittance cathode developments and diagnostics are very important. Conventional thermal emittance measurements for the high gradient gun are time-consuming and thus thermal emittance is not measured as frequently as quantum efficiency during the lifetime of photocathodes, although both are important properties for the photoinjector optimizations. In this paper, a single shot measurement of photoemission transverse momentum, i.e., thermal emittance per rms laser spot size, is proposed for photocathode RF guns. By tuning the gun solenoid focusing, the electrons transverse momenta at the cathode are imaged to a downstream screen, which enables a single shot measurement of both the rms value and the detailed spectra of the photoelectrons transverse momenta. Both simulations and proof of principle experiments are reported., Comment: 9 pages, 15 figures

A non-resonant streaming instability driven by cosmic-ray currents, also called Bell's instability, is proposed as a candidate for providing the required magnetic turbulence of efficient diffusive shock accelerations. To demonstrate the saturation level and mechanism of the non-resonant streaming instability in a laboratory environment, we attempt to develop an experiment at the Photo Injector Test Facility at DESY, Zeuthen site (PITZ). As an electron beam is used to replace the proton beam to carry the cosmic-ray current in our experiment, the polarization of the non-resonant streaming instability will be modified from the left-handed (LH) mode to the right-handed (RH) mode. The theoretical instability analysis shows that the growth rate of this RH non-resonant mode may be smaller than it of the LH resonant mode. However the LH resonant mode can be ignored in our experiment while the expected wavelength is longer than the used plasma cell. The results of PIC simulations will also support this contention and the occurrence of non-resonant streaming instability in our experiment.

Temporally-modulated electron beams have a wide array of applications ranging from the generation of coherently-enhanced electromagnetic radiation to the resonant excitation of electromagnetic wakefields in advanced-accelerator concepts. Likewise producing low-energy ultrashort microbunches could be useful for ultra-fast electron diffraction and new accelerator-based light-source concepts. In this Letter we propose and experimentally demonstrate a passive microbunching technique capable of forming a picosecond bunch train at $\sim 6$~MeV. The method relies on the excitation of electromagnetic wakefields as the beam propagates through a dielectric-lined waveguide. Owing to the non-ultrarelativistic nature of the beam, the induced energy modulation eventually converts into a density modulation as the beam travels in a following free-space drift. The modulated beam is further accelerated to $\sim20$~MeV while preserving the imparted density modulation.

We report on an approach to produce quasi continuous-wave (cw) electron beams with an average beam current of milliamperes and a mean beam energy of a few MeV in a pulsed RF injector. Potential applications are in the planned laboratory astrophysics programs at DESY. The beam generation is based on field emission from a specially designed metallic field emitter. A quasi cw beam profile is formed over subsequent RF cycles at the resonance frequency of the gun cavity. This is realized by debunching in a cut disk structure accelerating cavity (booster) downstream of the gun. The peak and average beam currents can be tuned in beam dynamics simulations by adjusting operation conditions of the booster cavity. Optimization of the transverse beam size at specific positions (e.g., entrance of the plasma experiment) is performed by applying magnetic focusing fields provided by solenoids along the beam line. In this paper, the design of a microtip field emitter is introduced and characterized in electromagnetic field simulations in the gun cavity. A series of particle tracking simulations are conducted for multi-parametric optimization of the parameters of the produced quasi cw electron beams. The obtained results will be presented and discussed. In addition, measurements of the parasitic field emission (PFE) current (dark current) in the PITZ gun will be exemplarily shown to distinguish its order of magnitude from the produced beam current by the designed field emitter., Comment: 23 pages, 17 figures

This paper discusses the behavior of electron bunch charge produced in an L-band normal conducting radio frequency cavity (RF gun) from Cs2Te photocathodes illuminated with ps-long UV laser pulses when the laser transverse distribution consists of a flat-top core with Gaussian-like decaying halo. The produced charge shows a linear dependence at low laser pulse energies as expected in the quantum efficiency limited emission regime, while its dependence on laser pulse energy is observed to be much weaker for higher values, due to space charge limited emission. However, direct plug-in of experimental parameters into the space charge tracking code ASTRA yields lower output charge in the space charge limited regime compared to measured values. The rate of increase of the produced charge at high laser pulse energies close to the space charge limited emission regime seems to be proportional to the amount of halo present in the radial laser profile since the charge from the core has saturated already. By utilizing core + halo particle distributions based on measured radial laser profiles, ASTRA simulations and semi-analytical emission models reproduce the behavior of the measured charge for a wide range of RF gun and laser operational parameters within the measurement uncertainties., Comment: 15 pages, 16 figures, 2 tables