1. Serotonergic control of the developing cerebellum
- Author
-
Oostland, M., Wadman, Wytse, van Hooft, Hans, and Cellular and Computational Neuroscience (SILS, FNWI)
- Subjects
nervous system ,heterocyclic compounds - Abstract
The work described in this thesis gives insights in the mechanism behind the serotonergic control of the cerebellum during postnatal development. The findings present a powerful role for serotonin in the physiology of the developing cerebellum. The effects of the serotonergic control extend both spatially and temporally, while it is able to keep up its specialized effects by using an efficient mechanism through differential expression of the receptors studied in this thesis: 5-HT1, 5-HT2 and 5-HT3 receptors.
- Published
- 2013