146 results on '"Ooms, Lisa M."'
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2. INPP4B promotes PI3Kα-dependent late endosome formation and Wnt/β-catenin signaling in breast cancer
3. The mechanisms of class 1A PI3K and Wnt/β-catenin coupled signaling in breast cancer
4. The SH2-Containing Inositol Polyphosphate 5-Phosphatase, SHIP-2, Binds Filamin and Regulates Submembraneous Actin
5. Functional and Phenotypic Characterisations of Common Syngeneic Tumour Cell Lines as Estrogen Receptor-Positive Breast Cancer Models
6. Inositol polyphosphate 4-phosphatase II (INPP4B) is associated with chemoresistance and poor outcome in AML
7. The FDA-Approved Drug Pyrvinium Selectively Targets ER+ Breast Cancer Cells with High INPP4B Expression
8. Inositol polyphosphate 4-phosphatase II regulates PI3K/Akt signaling and is lost in human basal-like breast cancers
9. An ENU-induced mouse mutant of SHIP1 reveals a critical role of the stem cell isoform for suppression of macrophage activation
10. The INPP4B paradox: Like PTEN, but different
11. The FDA-Approved Drug Pyrvinium Selectively Targets ER + Breast Cancer Cells with High INPP4B Expression.
12. Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging
13. KEYNOTE SPEAKER 5: REGULATION OF PI3K/AKT-DEPENDENT BREAST CANCER GROWTH AND METASTASIS
14. INPP4B is Highly Expressed in Prostate Intermediate Cells and Its Loss of Expression in Prostate Carcinoma Predicts for Recurrence and Poor Long Term Survival
15. Reactive Oxygen Species Enhance Insulin Sensitivity
16. A late endosome signaling hub that couples PI3Kα and WNT/β-catenin signaling in breast cancer
17. PTEN and Other PtdIns(3,4,5)P3 Lipid Phosphatases in Breast Cancer
18. Analysis of Phosphatidylinositol 3,4,5 Trisphosphate 5-Phosphatase Activity by in vitro and in vivo Assays
19. Control of Glucocorticoid Receptor Levels by PTEN Establishes a Failsafe Mechanism for Tumor Suppression
20. AKT signaling promotes DNA damage accumulation and proliferation in polycystic kidney disease
21. Tranexamic acid is an active site inhibitor of urokinase plasminogen activator
22. PtdIns(3,4,5)P3-dependent Rac exchanger 1 (P-Rex1) promotes mammary tumor initiation and metastasis.
23. AKT signaling promotes DNA damage accumulation and proliferation in polycystic kidney disease.
24. β-catenin ablation exacerbates polycystic kidney disease progression
25. P-Rex1 and P-Rex2 RacGEFs and cancer
26. Regulation of PI3K effector signalling in cancer by the phosphoinositide phosphatases
27. β-catenin ablation exacerbates polycystic kidney disease progression.
28. PtdIns(3,4,5)P3-dependent Rac Exchanger 1 (PREX1) Rac-Guanine Nucleotide Exchange Factor (GEF) Activity Promotes Breast Cancer Cell Proliferation and Tumor Growth via Activation of Extracellular Signal-regulated Kinase 1/2 (ERK1/2) Signaling
29. The Phosphatidylinositol (3,4,5)-Trisphosphate-dependent Rac Exchanger 1·Ras-related C3 Botulinum Toxin Substrate 1 (P-Rex1·Rac1) Complex Reveals the Basis of Rac1 Activation in Breast Cancer Cells
30. The Inositol Polyphosphate 5-Phosphatase PIPP Regulates AKT1-Dependent Breast Cancer Growth and Metastasis
31. INPP4B is highly expressed in prostate intermediate cells and its loss of expression in prostate carcinoma predicts for recurrence and poor long term survival
32. PtdIns(3,4,5)P3-dependent Rac Exchanger 1 (PREX1) Rac-Guanine Nucleotide Exchange Factor (GEF) Activity Promotes Breast Cancer Cell Proliferation and Tumor Growth via Activation of Extracellular Signal-regulated Kinase 1/2 (ERK1/2) Signaling.
33. Silencer of Death Domains (SODD) Inhibits Skeletal Muscle and Kidney Enriched Inositol 5-Phosphatase (SKIP) and Regulates Phosphoinositide 3-Kinase (PI3K)/Akt Signaling to the Actin Cytoskeleton
34. Identification of a Proline-rich Inositol Polyphosphate 5-Phosphatase (PIPP)·Collapsin Response Mediator Protein 2 (CRMP2) Complex That Regulates Neurite Elongation
35. A Mutation in Synaptojanin 2 Causes Progressive Hearing Loss in the ENU-Mutagenised Mouse Strain Mozart
36. The role of the inositol polyphosphate 5-phosphatases in cellular function and human disease
37. P-Rex1 – a multidomain protein that regulates neurite differentiation
38. The inositol polyphosphate 5-phosphatases: traffic controllers, waistline watchers and tumour suppressors?
39. Inactivation of the Phosphoinositide Phosphatases Sac1p and Inp54p Leads to Accumulation of Phosphatidylinositol 4,5-Bisphosphate on Vacuole Membranes and Vacuolar Fusion Defects
40. The inositol polyphosphate 5-phosphatases: traffic controllers, waistline watchers and tumour suppressors?
41. The Inositol Polyphosphate 5-Phosphatase, PIPP, Is a Novel Regulator of Phosphoinositide 3-Kinase-dependent Neurite Elongation
42. Identification of a Novel Domain in Two Mammalian Inositol-polyphosphate 5-Phosphatases That Mediates Membrane Ruffle Localization
43. Analysis of Phosphatidylinositol 3,4,5 Trisphosphate 5-Phosphatase Activity by in vitro and in vivo Assays.
44. Inositol Polyphosphate 5-Phosphatases: Lipid Phosphatases With Flair
45. The Yeast Inositol Polyphosphate 5-Phosphatase Inp54p Localizes to the Endoplasmic Reticulum via a C-terminal Hydrophobic Anchoring Tail
46. The Yeast Inositol Polyphosphate 5-Phosphatases Inp52p and Inp53p Translocate to Actin Patches following Hyperosmotic Stress: Mechanism for Regulating Phosphatidylinositol 4,5-Bisphosphate at Plasma Membrane Invaginations
47. The Inositol Polyphosphate 5-Phosphatases and the Apurinic/Apyrimidinic Base Excision Repair Endonucleases Share a Common Mechanism for Catalysis
48. Cloning and Characterization of a 72-kDa Inositol-polyphosphate 5-Phosphatase Localized to the Golgi Network
49. Characterization of Two Isoforms of the Skeletal Muscle LIM Protein 1, SLIM1
50. The Cardiac Expression of Striated Muscle LIM Protein 1 (SLIM1) is Restricted to the Outflow Tract of the Developing Heart
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