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Aquagenic keratoderma (AK) or aquagenic wrinklingis a rare palmoplantar skin disease. It is sporadic orhereditary condition. It appears in childhood or youngadulthood and it is seen as multiple asymptomaticsmall shiny papules on the peripheral margin ofpalms and/or soles after submersion in water. Thepathogenesis and etiology of ASA remains unclear.Drugs sometimes trigger AK. Herein, we present thecase of a 29-year-old man who had begun treatmentwith gabapentin three weeks before the onset of hiscutaneous symptoms.

Melkersson-Rosenthal syndrome (MRS) is a rare disease characterized by a triad of relapsing or persistent orofacial edema, recurrent lower motor neuron facial nerve palsy and fissured tongue. Acute, painless, non-erythematosus orofacial edema is observed in all patients. We report a case of a 13-year-old girl who presented with a 2-year history of swelling of the upper lip, facial paralysis, and fissured tongue; she was treated successfully with dapsone.

Background: Clinical features, types of Kaposi sarcoma, and treatment outcomes have not been well‐defined in Turkey. In this study, we reviewed records of the patients who had been diagnosed with Kaposi sarcoma in the last decade in a single center and evaluated treatment results. Methods: Medical records of the Kaposi sarcoma patients seen in the last decade in a single tertiary center were evaluated in detail. Results: A total of 27 patients were identified; 18 patients had been checked for HHV8; and 16 of those patients were positive for HHV8. One patient was positive for HIV. Two patients having mycosis fungoides and myasthenia graves developed iatrogenic KS after immunosuppressive treatments. Interferon α was used in 21 patients; 8 patients achieved complete response; and 11 patients achieved a partial response. No serious side effects were observed. Systemic involvement did not develop in any patients except lymph node involvement in a patient with widespread skin lesions. [ABSTRACT FROM AUTHOR]

Background: Some studies have investigated the relationship between Behçet's disease (BD) and insulin resistance; however, since they did not exclude obese patients from their sample, it remains unclear whether BD itself causes insulin resistance independently of obesity. Methods: The study included 60 patients with BD and 45 age‐, gender‐, and body mass index (BMI)–matched healthy controls. Obese patients with a BMI of ≥30 kg/m² were excluded. Insulin resistance according to the homeostasis model assessment for insulin resistance (HOMA‐IR) and quantitative insulin sensitivity check index (QUICKI), fasting plasma glucose, and one‐hour and two‐hour plasma glucose in the oral glucose tolerance test (OGTT 1‐h and OGTT 2‐h PG, respectively) were evaluated in all patients. Results: The mean fasting plasma glucose levels and the rate of those with impaired glucose tolerance according to OGTT 2‐h PG were significantly higher in the BD patients compared to the controls. The rates of those with insulin resistance according to HOMA‐IR and QUICKI were significantly higher in the BD patients than in the controls. When compared to the control group, the rates of those with impaired fasting glucose and impaired glucose tolerance were significantly higher, and the mean QUICKI value was significantly lower in the active group, in contrast to the inactive group. Conclusions: Insulin resistance occurs in BD patients independently of obesity. In the follow‐up of BD patients, especially in the active phase, not only fasting blood glucose but also other diagnostic tests for insulin resistance should be added to the examination panels. [ABSTRACT FROM AUTHOR]

Byline: Fatma. Cengiz, Nazan. Emiroglu, Anil. Bahali, Dilek. Ozkaya, Ozlem. Su, Nahide. Onsun Background: There is limited data about the relationship between psoriasis and melanocytic lesions and melanoma. Immunologic pathways [...]

Byline: Ozlem. Su, Didem. Dizman, Nahide. Onsun, Dilek. Ozkaya, Zeynep. Tosuner, Anil. Bahali, Cuyan. Demirkesen Sir, Clear cell acanthoma, first described by Degos in 1962, [sup][1] was originally thought to [...]