34 results on '"Onnis GL"'
Search Results
2. The reproducibility of CIN diagnoses among different pathologists: data from histology reviews from a multicenter randomized study.
- Author
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Dalla Palma P, Giorgi Rossi P, Collina G, Buccoliero AM, Ghiringhello B, Gilioli E, Onnis GL, Aldovini D, Galanti G, Casadei G, Aldi M, Gomes VV, Giubilato P, and Ronco G
- Subjects
- Adenocarcinoma epidemiology, Adult, Female, Humans, Italy epidemiology, Neoplasms, Squamous Cell epidemiology, Observer Variation, Reproducibility of Results, Uterine Cervical Dysplasia epidemiology, Uterine Cervical Neoplasms epidemiology, Adenocarcinoma diagnosis, Neoplasms, Squamous Cell diagnosis, Uterine Cervical Dysplasia diagnosis, Uterine Cervical Neoplasms diagnosis
- Abstract
The reproducibility of cervical histology diagnoses is critical for efficient screening and to evaluate the effectiveness of new technologies. The vast majority of cervical intraepithelial neoplasia (CIN) diagnoses reported in the New Technologies for Cervical Cancer study were blindly reviewed by 2 independent pathologists. Only H&E-stained slides were used for the review. The reviewers were asked to reclassify cases using the following categories: normal CIN 1, CIN 2, CIN 3, and squamous and glandular invasive cancer. We reviewed 1,003 cases. The interobserver agreement was 0.36 (95% confidence interval [CI], 0.32-0.40) with an unweighted kappa and 0.54 with a weighted kappa (95% CI, 0.50-0.58). The kappa values from dichotomous classifications with the threshold at CIN 2 were 0.69 (95% CI, 0.64-0.73) and 0.57 (95% CI, 0.51-0.63) with the threshold at CIN 3. The CIN 2 diagnosis had the lowest class-specific agreement, with fewer than 50% of cases confirmed by the panel members, which supports the fact that CIN 2 is not a well-defined stage in the pathogenesis of cervical neoplasia.
- Published
- 2009
- Full Text
- View/download PDF
3. Colposcopy, cytology and HPV-DNA testing in HIV-positive and HIV-negative women.
- Author
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Torrisi A, Del Mistro A, Onnis GL, Merlin F, Bertorelle R, and Minucci D
- Subjects
- Adult, Carcinoma diagnosis, Cervix Uteri cytology, Comorbidity, Female, Follow-Up Studies, HIV Seronegativity, Humans, Middle Aged, Papillomavirus Infections epidemiology, Polymerase Chain Reaction, Risk Assessment, Sensitivity and Specificity, Tumor Virus Infections epidemiology, Tumor Virus Infections prevention & control, Uterine Cervical Neoplasms diagnosis, Cervix Uteri pathology, Colposcopy methods, DNA, Viral analysis, HIV Seropositivity epidemiology, Papillomaviridae isolation & purification, Papillomavirus Infections diagnosis, Tumor Virus Infections diagnosis
- Abstract
In this study we examined the incidence of colposcopic-colpocytologic findings and analyzed Human Papilloma Virus (HPV)-DNA testing by Polymerase Chain Reaction (PCR) in 104 Human Immunodeficiency Virus (HIV) serous positive women (Group 1) and 218 HIV-negative women (control Groups 2 and 3). The aim of the study was to evaluate the most appropriate and efficacious diagnostic methods for screening programs for cervical cancer in HIV-positive women. For Group 1 we also considered the value of CD4+ T-lymphocytes and morphologic and molecular follow-up from 3 to 6 months. The results showed that the abnormal transformation zone (ANTZ) was present in 66.3% of the cases in Group 1 compared with 31.4% in control-Group 2 (p<0.001), and with 58.93% of the cases in control-Group 3 (p=0.257); intraepithelial squamous lesions (SIL) were found in 50% vs 5.66% (p<0.001) and vs 56.25% of the cases (p=0.433), respectively. In 28.85% of the HIV-positive patients the first cytological screening exam was not evaluable due to inflammation but in 56.67% of the cases colposcopy revealed ANTZ. The subsequent colpocytological checkup after therapy showed 10 cases (30%) of low risk squamous intraepithelial lesions (LSIL) and two cases (6.6%) of high risk squamous intraepithelial lesions (HSIL). HPV-DNA testing by PCR was positive in 53.8% of the cases in Group 1, in 6.6% in control-Group 2 and in 42% in control-Group 3. In HIV-positive patients multiple HPV genotypes were simultaneously present in 21.43% of the cases and high risk genotypes were present in 70% of the cases of HSIL. In Group 1, 36.61% of the cases had lesions of the lower genital tract. The value of CD4+ T-lympocytes was <200 cells/ml in 30% of the cases of HSIL. Our data, like those of other Authors, confirm a high incidence of HSIL, abnormal colposcopic findings, and HPV infections in HIV-positive women with respect to control-Group 2, while there was not much difference between Group 1 and control-Group 3. Such frequency again suggests that an integrated morphological diagnostic approach with colposcopy-colpocytology in the screening of immunosuppressed subjects would be worthwhile.
- Published
- 2000
4. Simultaneous combined ultrasound and gynaecological examination for a more in depth clinical diagnosis. A personal practice.
- Author
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Onnis A and Onnis GL
- Subjects
- Clinical Protocols, Female, Humans, Ultrasonography, Genital Diseases, Female diagnosis, Genital Diseases, Female diagnostic imaging, Physical Examination
- Published
- 1996
5. Risk factors for complicating infections after cesarean section.
- Author
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Litta P, Vita P, Konishi de Toffoli J, and Onnis GL
- Subjects
- Endometritis etiology, Female, Humans, Pregnancy, Risk Factors, Surgical Wound Infection etiology, Urinary Tract Infections etiology, Cesarean Section, Infections etiology, Postoperative Complications
- Abstract
In this study of 906 women who underwent Cesarean Section without the use of an antibiotic prophylactic it has been confirmed that age, labour in course and the premature rupture of the membrane are clinical parameters that are statistically significant for unspecified fever/endometritis or for infections of the wound and that hemoglobin and hematocrit values below 9 gr/dl and at 35% post-operation are significant for infections of the wound. 13.2% women had complicating infections of which 1.3% were infections of the wound, 0.6% were endometritis, 7.2% were unspecified fever and 4.1% were urinary infections. The Authors show that preventive measures in some areas could be as effective as chemoprophylaxis.
- Published
- 1995
6. Colposcopy, colpocytology and the vaginal ecosystem. Oncological, bacteriological and hormonal evaluation in a series of 400 women.
- Author
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Torrisi A, Onnis GL, and Minucci D
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Bacteria isolation & purification, Cytodiagnosis, Ecosystem, Female, Humans, Male, Middle Aged, Papillomaviridae, Papillomavirus Infections pathology, Papillomavirus Infections virology, Retrospective Studies, Tumor Virus Infections, Cervix Uteri pathology, Colposcopy, Uterine Cervical Neoplasms pathology, Vagina metabolism, Vagina microbiology, Vagina pathology, Vaginal Neoplasms microbiology, Vaginal Neoplasms pathology
- Abstract
The Authors retrospectively considered colpocytological and colposcopic findings in a series of 400 women, aged 16 to 83 years, presenting for the first time at the Oncological Gynaecology Unit of the Institute of Gynaecology and Obstetrics of Padua University between 1991 and 1992. In addition to oncological evaluation, the bacteriological profile and hormone status of cytological samples were formulated in all cases. The most common oncological finding was a cell morphology within normal limits (67%), followed by reactive and reparative changes (19%) and low-grade squamous intraepithelial lesions (SIL, 12%). Histological findings correlated well with the cytological diagnosis, though low-grade SIL was over-estimated. As for the bacteriological profile, a mixed flora was most frequent (56.7%) followed, especially in fertile age, by Döderlein's bacillus (20%) and vaginosis (15.5%). Colposcopy most frequently revealed ectopia and/or a normal transformation zone (50.7%) and dystrophic mucosa (21%). An abnormal transformation zone was more common among women with a moderate-to-abundant flora. Fifteen male partners were also checked: cellular changes typical of human papilloma virus infection were found in 40% and colposcopic findings compatible with said virus were observed in 26.6% of cases. These results confirm that colpocytology provides a complete and simultaneous evaluation not only of cell morphology, but also of the bacterial population and hormones in the vaginal ecosystem. It is therefore the method of choice in screening for cervical and vaginal neoplasms and an effective means for simultaneously evaluating vaginal flora and hormone status.
- Published
- 1994
7. Endometrial cytology for the prevention and early diagnosis of endometrial neoplasias.
- Author
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Torrisi A, Onnis GL, Trovò S, and Minucci D
- Subjects
- Aged, Atrophy, Biopsy, Needle, Colposcopy, Endometrial Hyperplasia diagnosis, Endometrial Neoplasms prevention & control, Female, Follow-Up Studies, Humans, Menopause, Middle Aged, Endometrial Neoplasms diagnosis, Endometrium pathology
- Abstract
One hundred and forty women, aged between 46 and 70 years, were submitted to periodic colpocytologic, colposcopic and cytologic endometrial checking. None of the patients had been treated by estrogenic therapy. We evaluated the possible morphologic modifications of the endometrium over time by periodic cytologic checks, personalized on the basis of the anamnestic and actual risks of the patients. From the data it was noted that the endometrium in pre- and in post-menopause may present changes in the absence of substitutive therapies. In fact in women in post-menopause we found 33% of atrophic endometria at first check, going down to 22.3% at the second, while the incidence of hyperplasia increased slightly. At the second check we always diagnosed 2 cases (2.6%) presenting atypia, confirmed by subsequent curettage. At the third check an increase was observed of atrophic endometria (41.8%) and a reduction of focal hyperplasia (4%). Among women in pre-menopause there was a high incidence of endometria with focal hyperplasia, 37.5% at the first check, 40.6% at the second and 39.6% at the third; hyperplasia in 11.5% of cases at first check, 12.5% at the second and 6.3% at the third; presence of atypia in 1.5% of cases at the second check and 3.2% at the third. Curettages subsequently confirmed diagnosis in these last three patients. In the cases where small fragments of endometrial tissue appeared in the cytological sample we found good agreement between histologic and cytologic diagnoses; the latter slightly overestimated focal hyperplasia and diffuse hyperplasia.(ABSTRACT TRUNCATED AT 250 WORDS)
- Published
- 1993
8. Risk of progression in low grade squamous intraepithelial lesions.
- Author
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Insacco E, De Matteis B, Cinel A, Onnis GL, and Minucci D
- Subjects
- Adult, Aged, Female, Humans, Middle Aged, Papillomaviridae, Prognosis, Risk Factors, Tumor Virus Infections complications, Tumor Virus Infections diagnosis, Uterine Cervical Dysplasia complications, Vaginal Smears, Carcinoma in Situ diagnosis, Uterine Cervical Dysplasia diagnosis, Uterine Cervical Neoplasms diagnosis
- Abstract
In order to evaluate the evolution of the low grade dysplasia using colpocytologic follow-up, 150 women, enrolled in this study, were submitted to yearly colpocytologic control for a period of four years. The rate of progression toward more severe forms was very low; three cases (2.14%) in the first year, one case (0.7%) in the second and two cases (2.32%) in the fourth. Eighty-eight per cent of the patients had cytologic signs of Human Papilloma Virus infection detected in cytologic and histologic examination.
- Published
- 1992
9. Colposcopic pictures of Abnormal Transformation Zone (ANTZ): colpocytological and histological findings.
- Author
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Minucci D, Torrisi A, Onnis GL, Cinel A, Insacco E, and Trovò S
- Subjects
- Adult, Biopsy, Colposcopy, Evaluation Studies as Topic, Female, Humans, Sensitivity and Specificity, Uterine Cervicitis pathology, Carcinoma in Situ pathology, Cervix Uteri pathology, Uterine Cervical Neoplasms pathology
- Abstract
The Authors have examined the correlation between the colposcopic pictures of the Abnormal Transformation Zone (ANTZ), in its varying degrees, and the colpocytological and histological examinations in order to seek a better definition of the indications of carrying out aimed biopsies. From our results a good agreement has been observed from the colpocytological and histological examination and the colposcopic pictures of the ANTZ. In patients with colposcopic images of ANTZ G2 the colpocytological examination diagnosed a CIN 3 in 80.6% of cases, invasive carcinoma in 6.4%, and in histologic examination CIN 3 in 71% and microinvasive carcinoma in 10.7%. Instead in the ANTZ G1, CIN 3 was revealed colpocytologically in 7.9% of the cases and histologically in 7.3%. Among these last, in half of the cases, the focuses of CIN 3 were present at the level of third inferior of the cervical canal. Finally, in ANTZ G0 there was cytological evidence in 6.6% of cases of CIN 3 with a histological correspondence of 3.9%. In particular the focuses of CIN 3, small and limited, had resulted from biopsies carried out on some glandular openings not clearly attributable to ANTZ G1. With regard to the opportuneness of carrying out aimed biopsies, mandatory in the cases of ANTZ G2, we feel it would be useful to carry them out also for ANTZ G1, above all if alterations are diagnosed at the colpocytologic examinations, and in ANTZ G0 if colpocytological alterations are present. Therefore integrating colposcopic and colpocytologic examinations and aiming the biopsies would seem to lead to good diagnostic reliability and adequate successive personalized treatment.
- Published
- 1992
10. Cytological patterns of primary malignant uterine fibrous histiocytoma. A case report.
- Author
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Torrisi A, Giorgino F, Onnis GL, and Minucci D
- Subjects
- Female, Histiocytoma, Benign Fibrous diagnosis, Histiocytoma, Benign Fibrous drug therapy, Humans, Middle Aged, Uterine Neoplasms diagnosis, Uterine Neoplasms drug therapy, Histiocytoma, Benign Fibrous pathology, Uterine Neoplasms pathology
- Abstract
The Authors have reported the cytological patterns of malignant primitive uterine fibrous histiocytoma of a 57 year old woman. The endometrial cytological sampling was performed by an aspiration technique using a feeding-tube; a necrotic-haemorrhagic background filled with hymphocytes and polymorphonuclear leukocytes, and a mixture of highly anaplastic histiocytic and fibroblastic type cells, associated with undifferentiated small round cells, has been described. The result of the histological examination performed on the surgical specimen was the following: polymorphic malignant neoplasia characterized by spindle-like and giant plurinucleated cells, phagocytosis features, endoluminal polypoid growth, wide infiltration of the miometrium two thirds deep, vascular space invasion of the uterine wall and the hilus of the ovaries. The histological features and immunohistochemical analysis were consistent with malignant fibrous histiocytoma in the pleomorphic variety.
- Published
- 1990
11. Possible similar hormone answers in vaginal and oral hollow cytology.
- Author
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Hulpe C, Onnis GL, and Terribile Wiel Marin V
- Subjects
- Adult, Atrophy, Epithelial Cells, Epithelium pathology, Evaluation Studies as Topic, Female, Humans, Menopause metabolism, Mouth Mucosa cytology, Pregnancy, Staining and Labeling, Vagina cytology, Estrogens metabolism, Menstrual Cycle metabolism, Mouth Mucosa pathology, Vagina pathology
- Published
- 1990
12. Role of second look laparotomy in multidisciplinary treatment and in the follow up of advanced ovarian cancer.
- Author
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Maggino T, Tredese F, Valente S, Marchesoni D, Brandes A, Menighetti M, and Onnis GL
- Subjects
- Carcinoma drug therapy, Cyclophosphamide administration & dosage, Doxorubicin administration & dosage, Drug Therapy, Combination, Female, Follow-Up Studies, Humans, Neoplasm Staging, Ovarian Neoplasms drug therapy, Prognosis, Reoperation, Carcinoma surgery, Laparotomy, Ovarian Neoplasms surgery
- Abstract
Surgical re-examination after first line surgery followed by chemotherapy is an absolutely necessary step in the course of integrated treatment of advanced ovarian epithelial tumours. Our personal experience of surgical re-staging and reductive surgery in 48 patients affected by ovarian tumours stage III and IV (FIGO), by laparotomic second look is reported. Repeated surgery succeeds in further reducing the neoplastic deposits or radicalizing the first intervention in 33% of the overall series; in 52% of the cases, the second look was negative for neoplasia; in 16% only, despite tumour finding no reductive surgery was possible. If only the cases presenting residual neoplasia after primary surgery are taken into account, tumour debulking was possible in 44% of the patients. The analysis of this series fully confirms the preliminary statement that the smaller the residual neoplasia after surgery, the greater the chances of success for chemotherapy in ovarian cancer. It confirms as well that the laparotomic second look is the only currently available way to usefully assess the full remission of the disease.
- Published
- 1983
13. Anterior spread of gynaecological neoplasias: reliability between some diagnostic procedures.
- Author
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Fabris F, Onnis GL, Vita P, and Valente S
- Subjects
- Cystoscopy, Female, Genitalia, Female pathology, Humans, Neoplasm Staging, Prognosis, Urethral Neoplasms diagnosis, Urinary Bladder pathology, Urinary Bladder Neoplasms diagnosis, Urography, Genital Neoplasms, Female pathology, Urethral Neoplasms secondary, Urinary Bladder Neoplasms secondary
- Abstract
The Authors report their experience regarding the comparison between pre-surgical clinico-instrumental staging and intra-operative staging in 134 patients with gynaecological neoplasias, particularly considering the spread to the lower urinary tract. The analysis of the results shows the moderate reliability of the cystoscopy in routinely evaluating extension of gynaecologic malignant diseases. The association of cytological urinary sediment examination with cystoscopy improves the possibility of a better evaluation. On the contrary, vesical biopsy, performed on the indications of cystoscopy and urinary cytology, and standard excretory urography prove to be insensitive indicators in diagnosing the spread of gynaecological malignancies.
- Published
- 1989
14. Critical review of dilatation and curettage in the diagnosis of malignant pathology of the endometrium.
- Author
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Danero S, Ricci MG, La Rosa R, Massafra C, Franchi F, Pitino C, Giovani M, and Onnis GL
- Subjects
- Female, Humans, Menopause, Uterine Neoplasms pathology, Dilatation and Curettage, Uterine Neoplasms diagnosis
- Abstract
The authors take into account all the Dilatation and Curettage done in the Obstetric and Gynaecological Clinic of the University of Siena during the past ten years, on hospitalized patients affected by postmenopausal uterine bleeding (PMB). Endometrial cancer resulted in 14.3% of the cases, in 41.4% of the cases the histological finding showed benign pathology of the endometrium, in 26.5% it was not possible to remove sufficient tissue from the uterine cavity for a diagnostic interpretation. In 14.6% of the cases, the diagnostic method showed premalignant or other than benign tissue. In the light of these results and considering the frequent complication which arise from this operative technique, the patients' stress, the high cost and the relatively low diagnostic reliability, the authors conclude that the routine use of this method is quite often excessive. The authors recommend, for the diagnosis of endometrial pathology, hysteroscopy associated with specific endometrial biopsy, undoubtedly the most up-to-date and less expensive technique, more acceptable to the patient and more sure than Dilatation and Curettage.
- Published
- 1986
15. Role of computed abdominal tomography (C.A.T. Scan) in the follow up of ovarian tumors.
- Author
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Maggino T, Ronsisvalle O, Tredese F, Valente S, Brandes A, Onnis GL, and Marchesoni D
- Subjects
- Cyclophosphamide administration & dosage, Doxorubicin administration & dosage, Drug Therapy, Combination, Evaluation Studies as Topic, False Negative Reactions, Female, Follow-Up Studies, Humans, Laparotomy, Ovarian Neoplasms drug therapy, Ovarian Neoplasms surgery, Probability, Ovarian Neoplasms diagnostic imaging, Tomography, X-Ray Computed
- Abstract
This study evaluates the possible use of computed tomography not as an alternative diagnostic method but, rather, as a supplement to laparotomy in patients treated for ovarian cancer. The following conclusions can be drawn: in patients presenting no clinical evidence of persistent or relapsing disease C.T. Scan is not a mandatory but, rather, an optional test since it entails 25% false negatives, a 66.6% predictive value and because the involved patients will need, in any case, a further intervention. Conversely, C.T. Scan is clearly indicated in patients presenting clinical evidence of disease. It can prove helpful in detecting metastases in areas that prove difficult to be clinically examined; in assessing whether the retroperitoneal areas conceal neoplastic tissue or in planning the right operation for masses that have been palpated only before chemotherapy, and then in regression. When, despite chemotherapy, tumour progresses, surgery may became useless, and the C.T. Scan may therefore prove helpful in defining the condition and guiding non surgical treatment. Therefore, in the follow up of ovarian cancer the C.T. Scan may be performed on the basis of clinical course, instead than on a rigid aprioristic planning.
- Published
- 1983
16. Proposal for protocol in the diagnosis of sterile couples.
- Author
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Marchetti M and Onnis GL
- Subjects
- Female, Humans, Male, Infertility diagnosis
- Published
- 1981
17. [Horton's arteritis. Anatomical-clinical study of 12 cases].
- Author
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Terribile Wiel Marin V, Salmaso R, Onnis GL, and Biscaro G
- Subjects
- Aged, Aged, 80 and over, Female, Fluorescent Antibody Technique, Humans, Male, Middle Aged, Giant Cell Arteritis pathology
- Published
- 1987
18. A new technique in endometrial sampling.
- Author
-
Onnis GL and Terribile Wiel Marin V
- Subjects
- Biopsy methods, Curettage instrumentation, Female, Humans, Endometrium pathology, Uterine Neoplasms pathology
- Abstract
The utility of endometrial cytology in the diagnosis of uterine pathology has led to the development of many methods of sampling; ours uses a rubber tube whose tip has been cut and in its place inserted a steel tip specially made, to the diameter of the tube, and 2-3 cm long. The withdrawal is normally carried out without any need for the dilation of the cervical canal and without having to pinch the neck of the uterus, the stell tip being pushed backwards and forwards by the extractor carrying out a curettage of the cavity. The material obtained is both abundant and of sufficient quality for a histological examination, besides the cytological one.
- Published
- 1987
19. The ovarian teratomas. A histopathological review of 77 cases.
- Author
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Terribile Wiel Marin V, Onnis GL, Gobbo F, and Salmaso R
- Subjects
- Diagnosis, Differential, Female, Humans, Ovarian Cysts pathology, Ovarian Neoplasms surgery, Ovary pathology, Ovarian Neoplasms pathology, Teratoma pathology
- Abstract
Seventy-seven cases of ovarian teratomas were studied according to examination modality of surgical specimens and to histologic patterns and frequency of different tissues components. The main histogenetic conjectures were debated also.
- Published
- 1988
20. Ultrasound evaluation in the follow-up of ovarian cancer today.
- Author
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Nardelli GB, Onnis GL, Lamaina V, and Petrillo MR
- Subjects
- Adenocarcinoma, Mucinous pathology, Combined Modality Therapy, Cystadenocarcinoma pathology, Endometriosis pathology, Female, Follow-Up Studies, Humans, Lymph Nodes pathology, Lymphatic Metastasis, Neoplasm Staging, Omentum pathology, Ovarian Neoplasms surgery, Ovary pathology, Reoperation, Ovarian Neoplasms pathology, Ultrasonography
- Abstract
From October 1982 through December 1986, standardized abdominal-pelvic sonography was performed on 257 patients with ovarian cancer scheduled to undergo surgery (laparoscopy, laparotomy). This U.S. test was evaluated by a gynaecologist who was informed of the clinical diagnosis and the findings of physical examination. The Authors selected 110 patients with ovarian cancer, underwent a second look laparotomy, for both diagnostic and therapeutic purposes. The sensitivity (53%), the specificity (68%), the predictive value (78%) and the accuracy 71.8%) of ultrasound for detecting disease have been evaluated to assess its usefulness as a non invasive diagnostic modality in these patients.
- Published
- 1987
21. Diagnostic integrated program in breast pathology: clinical experiences.
- Author
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Litta P, Nardelli GB, Maggino T, Azzena A, Valente S, Marchesoni D, Onnis GL, and Fais GF
- Subjects
- Age Factors, Biopsy, Breast pathology, Breast Neoplasms pathology, Female, Galactorrhea pathology, Humans, Mammography, Medical History Taking, Nipples metabolism, Ultrasonography, Breast Neoplasms diagnosis
- Abstract
1068 patients were examined using a unified diagnostic protocol. 618 patients at high risk were screened out, and underwent further instrumental and surgical investigation. 17 cases of breast cancer were detected, while the remaining patients were addressed to an appropriate, highly reliable and repeatable follow-up for breast care.
- Published
- 1985
22. Pilo-sebaceous structures in the uterine cervix: case report.
- Author
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Chiarelli SM and Onnis GL
- Subjects
- Female, Humans, Middle Aged, Polyps pathology, Uterine Cervical Neoplasms pathology, Cervix Uteri pathology, Hair pathology, Sebaceous Glands pathology
- Published
- 1981
23. Electromyography of anal sphincters after radical gynecological surgery.
- Author
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Valente S, Fabris F, Onnis GL, and Laganara R
- Subjects
- Adult, Anal Canal physiopathology, Female, Humans, Hysterectomy, Middle Aged, Anal Canal physiology, Electromyography, Uterine Cervical Neoplasms surgery
- Abstract
In this study, the Authors report their own experience in electromyography of anal sphincters. The clinical evaluation concerns a clinical series of 14 patients suffering from carcinoma of the uterine cervix at SPS stage A and B, and undergoing a personalized radical hysterectomy during 1986. The protocol included a preoperative electromyographic and urodynamic evaluation and a post-operative re-evaluation 30-60 days after surgery. The pre-operative evaluation in both the urodynamic test and the electromyographic test showed bladder-urethral function in all the cases examined. The post-operative electromyographic evaluation was considered normal and did not show alterations in the sphincteral function in 9 cases (64.3%). In the remaining 5 cases (35.7%) the presence of sphincteral incoordination was shown. The analysis of the results shows that the use of electromyography, connected with the usual urodynamic study in gynaecological oncology, objectively recognises the sphincter-detrusorial situations characterized by dysuria and retention from a clinical-anamnestic point of view.
- Published
- 1988
24. Progestinic treatment of mastodynia. New suggestion for the follow-up.
- Author
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Onnis A, Nardelli GB, Mozzanega B, Lamaina V, Onnis GL, Maggino T, Litta P, and Marchetti M
- Subjects
- Breast Diseases diagnosis, Endometrium analysis, Estradiol, Female, Follow-Up Studies, Humans, Mammography, Receptors, Estrogen analysis, Receptors, Progesterone analysis, Breast Diseases drug therapy, Progestins therapeutic use
- Abstract
The problem of progestin treatment for benign breast disease and mastodynia is still dividing Clinicians and Searchers: the traditional methods of clinical investigation and follow-up do not allow any further step in the debate. In this work we evaluated the role of E2/Progesterone R.I.A. and thermography in monitoring the effect of progestin on BBD and found that only the latter can give useful informations, insufficient, however, to direct the treatment. If we want to be able to select the patients suitable to be treated by progesterone, we must know the tissutal hormone receptivity and be able to reexamine it during the treatment to verify the effectiveness of the administered drug. These informations can be obtained through the assay of Estradiol and Progesterone Receptors in the most accessible hormone-dependent tissue: the endometrium. Our data point out a quite different behaviour of Estradiol and Progesterone cytoplasmic Receptors in the endometrium of women with mastodynia and controls. The knowledge of these informations in the single patient will let us come out from subjectivity when deciding about BBD therapy or when trying to correct unsatisfactory treatments.
- Published
- 1984
25. Intraductal breast papilloma in adolescent. Case report.
- Author
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Onnis GL, Chiarelli SM, and Dalla Palma P
- Subjects
- Adolescent, Breast Neoplasms pathology, Diagnosis, Differential, Female, Humans, Papilloma pathology, Breast Neoplasms diagnosis, Papilloma diagnosis
- Abstract
Cytological and histological finding of an intraductal breast papilloma in a 14 year old girl is reported. The differential diagnosis with other adolescent breast pathology is discussed.
- Published
- 1983
26. Simple asymptomatic orthotopic ureterocele in pregnancy: analysis of a clinical case.
- Author
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Valente S, Fabris F, Onnis GL, and Nardelli GB
- Subjects
- Adult, Female, Humans, Pregnancy, Ultrasonography, Urography, Pregnancy Complications diagnosis, Ureterocele diagnosis
- Abstract
In the present paper the authors, taking for a starting point the occasional recognition of an asymptomatic orthotopic ureterocele in pregnancy, refer to the present knowledge of its embryology, pathological anatomy and the form of therapeutic approach. In the light of such experience they confirm the role of clinical-instrumental diagnostic investigations of purely gynecological and obstetric pertinence in the recognition of pathologies of urological interest.
- Published
- 1987
27. Advantage of a particular method in cytodiagnosis by aspiration with a fine needle.
- Author
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Onnis GL and Terribile Wiel Marin V
- Subjects
- Biopsy, Needle methods, Equipment Design, Humans, Needles, Biopsy, Needle instrumentation, Cytodiagnosis instrumentation
- Abstract
The indisputable utility of needle aspiration in early diagnosis induced us to improve a personal method of withdrawal. This is based on the use of an opposite mounting studied and patented by us, in order to maintain the single-use syringe in constant aspiration; also in some needles modified by a longitudinal split with a cutting edge.
- Published
- 1988
28. Intraductal papilloma of the breast in a 14-year old girl. Case report.
- Author
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Graziottin A, Velasco M, Onnis GL, and Generali S
- Subjects
- Adolescent, Age Factors, Breast Neoplasms surgery, Female, Humans, Mammography, Papilloma surgery, Transillumination, Breast Neoplasms diagnosis, Papilloma diagnosis
- Published
- 1982
29. Mycoplasma, chlamydia and viruses in the female genital tract and infertility: clinical experience.
- Author
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Marchesoni D and Onnis GL
- Subjects
- Chlamydia trachomatis, Endometrium microbiology, Endometrium pathology, Female, Herpesviridae Infections complications, Humans, Infertility, Male etiology, Male, Papillomaviridae, Polyomaviridae, Tumor Virus Infections complications, Chlamydia Infections complications, Infertility, Female etiology, Mycoplasma Infections complications
- Abstract
In the University of Padua during the last ten years the chlamydia trachomatis, mycoplasma and viruses were studied in human infertility. The results show the influence on chlamydia and ureaplasma urealyticum, in some cases with different pathogenetic mechanisms. The results are discussed.
- Published
- 1987
30. Determination of ER in ovarian cancer using monoclonal antibody technology.
- Author
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Nardelli GB, Lamaina V, Dal Pozzo M, and Onnis GL
- Subjects
- Adult, Aged, Cell Nucleus ultrastructure, Cytoplasm ultrastructure, Cytosol ultrastructure, Female, Humans, Immunoenzyme Techniques, Middle Aged, Ovary pathology, Antibodies, Monoclonal, Ovarian Neoplasms pathology, Receptors, Estrogen analysis
- Abstract
The Monoclonal Antibody technology has been used in 29 cases of ovarian cancer. The immuno-enzyme-assay detected positive levels of estrogen cytoplasmatic receptor in 51.8% of the cases as well as in the nuclear (51.8%). Moreover, the ER/EIA technique screened positive levels of Total ER (ER/t) in 72.4% versus 65.5% obtained by DCC-method. 24.1% of the cases had negative ER/t levels observed by EIA. The monoclonal antibody anti-ER is a very interesting method for studying hormone-dependent tissue, because it uses an immunological binding to antigenic protein (receptor).
- Published
- 1987
31. Anatomopathologic aspects of ovarian endometriosis.
- Author
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Onnis GL, Chiarelli S, Terribile Wiel Marin V, and Salmaso R
- Subjects
- Adolescent, Adult, Endometriosis pathology, Female, Genital Neoplasms, Female epidemiology, Genital Neoplasms, Female pathology, Humans, Middle Aged, Ovarian Neoplasms pathology, Endometriosis epidemiology, Ovarian Neoplasms epidemiology
- Abstract
The Authors reviewed 284 cases of endometriosis; it interested all age ranges with prevalence of four and fifth decades and showed a range of 19-68 years. Favourite sites was ovary with 271 cases, remaining were: tubes, omentum, vagina, vulva and cecum. The histological appearance is similar to normal endometrium but these foci react to hormonal stimulation variably.
- Published
- 1988
32. Coexisting Brenner tumor and struma ovarii: case report.
- Author
-
Chiarelli SM and Onnis GL
- Subjects
- Female, Humans, Middle Aged, Brenner Tumor pathology, Neoplasms, Multiple Primary pathology, Ovarian Neoplasms pathology, Struma Ovarii pathology
- Published
- 1980
33. Tumors of salivary glands. Review of 479 cases with particular reference to histological types, site, age and sex distribution.
- Author
-
Martin VT, Salmaso R, and Onnis GL
- Subjects
- Adolescent, Adult, Age Factors, Aged, Child, Female, Humans, Italy, Male, Middle Aged, Salivary Gland Neoplasms pathology, Sex Factors, Salivary Gland Neoplasms epidemiology
- Abstract
479 cases of tumors of salivary glands were examined at the Institute of Surgical Pathology of the University of Padua during the years 1973-1986; all these were reviewed. The diagnosis of individual tumors was based on the World Health Organization classification. Tumors were analyzed considering the histological type, sex, age and site. Primary tumors of epithelial origin were 91.8%. The principal site was the parotid (78.1%) while the submandibular gland forms the second largest group (14.57%). The malignant forms increase with age and were more common in submandibular and sublingual glands than the parotid. Connective tissue tumors were rare; 50% were hemangiomas that occur in children and young people; the only malignant neoplasias of soft tissue were 2 cases of rhabdomyosarcoma.
- Published
- 1989
34. [Preliminary study on diagnostic cytology of lesions of the oral cavity].
- Author
-
Onnis GL, Terribile Wiel Marin V, Salmaso R, and Miotti A
- Subjects
- Cytodiagnosis methods, Humans, Mouth Neoplasms pathology
- Published
- 1987
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