192,816 results on '"Ong, A"'
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2. Slung Sky Glitter
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Ong, Agnes Hanying
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- 2024
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3. Notes
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Ong, Andrew
- Published
- 2023
4. 2. Topographies of Power
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Ong, Andrew
- Published
- 2023
5. Half Title Page
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Ong, Andrew
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- 2023
6. References
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Ong, Andrew
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- 2023
7. Half Title Page, Title Page, Copyright, Dedication
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Ong, Andrew
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- 2023
8. 5. Gestures of Governance
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Ong, Andrew
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- 2023
9. 4. Frontier Accumulations
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Ong, Andrew
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- 2023
10. Epilogue
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Ong, Andrew
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- 2023
11. Index
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Ong, Andrew
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- 2023
12. Note on Transliterations
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Ong, Andrew
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- 2023
13. Contents
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Ong, Andrew
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- 2023
14. Preface
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Ong, Andrew
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- 2023
15. 3. Oscillations and Incongruities
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Ong, Andrew
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- 2023
16. Acknowledgments
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Ong, Andrew
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- 2023
17. 1. Peripheral Cosmopolitanisms
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Ong, Andrew
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- 2023
18. List of Abbreviations
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Ong, Andrew
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- 2023
19. Plowman I Keep Seeing I Tell My
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Ong, Agnes Hanying
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- 2023
20. Fifty Years in the Karen Revolution in Burma: The Soldier and the Teacher by Saw Ralph and Naw Sheera (review)
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Ong, Andrew
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- 2021
21. I ♥ Oklahoma! by Roy Scranton (review)
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Ong, Agnes Hanying
- Published
- 2023
22. VERITAS and multiwavelength observations of the Blazar B3 2247+381 in response to an IceCube neutrino alert
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Acharyya, Atreya, Adams, Colin B., Bangale, Priyadarshini, Bartkoske, J. T., Benbow, Wystan, Buckley, James H., Chen, Yu, Christiansen, Jodi, Chromey, Alisha, Duerr, Anne, Errando, Manel, Godoy, Miguel E., Falcone, Abe, Feng, Qi, Foote, Juniper, Fortson, Lucy, Furniss, Amy, Hanlon, William, Hanna, David, Hervet, Olivier, Hinrichs, Claire E., Holder, Jamie, Humensky, Thomas B., Jin, Weidong, Johnson, Madalyn N., Kaaret, Philip, Kertzman, Mary P., Kherlakian, Maria, Kieda, David, Kleiner, Tobias K., Korzoun, Mx. Nikolas, Krennrich, Frank, Kumar, Sajan, Lang, Mark J., Lundy, Matthew, McGrath, Conor, Meyer, Eileen T., Millard, Matthew J., Millis, John, Mooney, Connor, Moriarty, Patrick, Mukherjee, Reshmi, Ning, Wenmeng, O'Brien, Stephan, Ong, Rene A., Pohl, Martin, Pueschel, Elisa, Quinn, John, Rabinowitz, Pazit L., Ragan, Ken, Reynolds, Paul, Ribeiro, Deivid, Roache, Emmet Thomas, Ryan, Jamie L., Sadeh, Iftach, Sadun, Alberto, Saha, Lab, Santander, Marcos, Sembroski, Glenn H., Shang, Ruo-Yu, Splettstoesser, Megan, Tak, Donggeun, Talluri, Anjana K., Tucci, James V., Valverde, Janeth, Williams, David A., Wong, Sam L., Woo, Jooyun, Abbasi, R., Ackermann, M., Adams, J., Agarwalla, S. K., Aguilar, J. A., Ahlers, M., Alameddine, J. M., Amin, N. M., Andeen, K., Argüelles, C., Ashida, Y., Athanasiadou, S., Axani, S. N., Babu, R., Bai, X., V., A. Balagopal, Baricevic, M., Barwick, S. W., Bash, S., Basu, V., Bay, R., Beatty, J. J., Tjus, J. Becker, Beise, J., Bellenghi, C., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Blaufuss, E., Bloom, L., Blot, S., Bontempo, F., Motzkin, J. Y. Book, Meneguolo, C. Boscolo, Böser, S., Botner, O., Böttcher, J., Braun, J., Brinson, B., Brisson-Tsavoussis, Z., Brostean-Kaiser, J., Brusa, L., Burley, R. T., Butterfield, D., Campana, M. A., Caracas, I., Carloni, K., Carpio, J., Chattopadhyay, S., Chau, N., Chen, Z., Chirkin, D., Choi, S., Clark, B. A., Coleman, A., Coleman, P., Collin, G. H., Connolly, A., Conrad, J. M., Corley, R., Cowen, D. F., De Clercq, C., DeLaunay, J. J., Delgado, D., Deng, S., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., DeYoung, T., Diaz, A., Díaz-Vélez, J. C., Dierichs, P., Dittmer, M., Domi, A., Draper, L., Dujmovic, H., Durnford, D., Dutta, K., DuVernois, M. A., Ehrhardt, T., Eidenschink, L., Eimer, A., Eller, P., Ellinger, E., Mentawi, S. El, Elsässer, D., Engel, R., Erpenbeck, H., Esmail, W., Evans, J., Evenson, P. A., Fan, K. L., Fang, K., Farrag, K., Fazely, A. R., Fedynitch, A., Feigl, N., Fiedlschuster, S., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Fukami, S., Fürst, P., Gallagher, J., Ganster, E., Garcia, A., Garcia, M., Garg, G., Genton, E., Gerhardt, L., Ghadimi, A., Girard-Carillo, C., Glaser, C., Glüsenkamp, T., Gonzalez, J. G., Goswami, S., Granados, A., Grant, D., Gray, S. J., Griffin, S., Griswold, S., Groth, K. M., Guevel, D., Günther, C., Gutjahr, P., Ha, C., Haack, C., Hallgren, A., Halve, L., Halzen, F., Hamacher, L., Hamdaoui, H., Minh, M. Ha, Handt, M., Hanson, K., Hardin, J., Harnisch, A. A., Hatch, P., Haungs, A., Häußler, J., Helbing, K., Hellrung, J., Hermannsgabner, J., Heuermann, L., Heyer, N., Hickford, S., Hidvegi, A., Hill, C., Hill, G. C., Hmaid, R., Hoffman, K. D., Hori, S., Hoshina, K., Hostert, M., Hou, W., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., Hymon, K., Ishihara, A., Iwakiri, W., Jacquart, M., Jain, S., Janik, O., Jansson, M., Jeong, M., Jin, M., Jones, B. J. P., Kamp, N., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Kardum, L., Karg, T., Karl, M., Karle, A., Katil, A., Katz, U., Kauer, M., Kelley, J. L., Khanal, M., Zathul, A. Khatee, Kheirandish, A., Kiryluk, J., Klein, S. R., Kobayashi, Y., Kochocki, A., Koirala, R., Kolanoski, H., Kontrimas, T., Köpke, L., Kopper, C., Koskinen, D. J., Koundal, P., Kowalski, M., Kozynets, T., Krieger, N., Krishnamoorthi, J., Krishnan, T., Kruiswijk, K., Krupczak, E., Kumar, A., Kun, E., Kurahashi, N., Lad, N., Gualda, C. Lagunas, Lamoureux, M., Larson, M. J., Lauber, F., Lazar, J. P., DeHolton, K. Leonard, Leszczyńska, A., Liao, J., Lincetto, M., Liu, Y. T., Liubarska, M., Love, C., Lu, L., Lucarelli, F., Luszczak, W., Lyu, Y., Madsen, J., Magnus, E., Mahn, K. B. M., Makino, Y., Manao, E., Mancina, S., Mand, A., Sainte, W. Marie, Mariş, I. C., Marka, S., Marka, Z., Marsee, M., Martinez-Soler, I., Maruyama, R., Mayhew, F., McNally, F., Mead, J. V., Meagher, K., Mechbal, S., Medina, A., Meier, M., Merckx, Y., Merten, L., Mitchell, J., Montaruli, T., Moore, R. W., Morii, Y., Morse, R., Moulai, M., Mukherjee, T., Naab, R., Nakos, M., Naumann, U., Necker, J., Negi, A., Neste, L., Neumann, M., Niederhausen, H., Nisa, M. U., Noda, K., Noell, A., Novikov, A., Pollmann, A. Obertacke, O'Dell, V., Olivas, A., Orsoe, R., Osborn, J., O'Sullivan, E., Palusova, V., Pandya, H., Park, N., Parker, G. K., Parrish, V., Paudel, E. N., Paul, L., Heros, C. Pérez de los, Pernice, T., Peterson, J., Pizzuto, A., Plum, M., Pontén, A., Popovych, Y., Rodriguez, M. Prado, Pries, B., Procter-Murphy, R., Przybylski, G. T., Pyras, L., Raab, C., Rack-Helleis, J., Rad, N., Ravn, M., Rawlins, K., Rechav, Z., Rehman, A., Resconi, E., Reusch, S., Rhode, W., Riedel, B., Rifaie, A., Roberts, E. J., Robertson, S., Rodan, S., Rongen, M., Rosted, A., Rott, C., Ruhe, T., Ruohan, L., Safa, I., Saffer, J., Salazar-Gallegos, D., Sampathkumar, P., Sandrock, A., Santander, M., Sarkar, S., Savelberg, J., Savina, P., Schaile, P., Schaufel, M., Schieler, H., Schindler, S., Schlickmann, L., Schlüter, B., Schlüter, F., Schmeisser, N., Schmidt, T., Schneider, J., Schröder, F. G., Schumacher, L., Schwirn, S., Sclafani, S., Seckel, D., Seen, L., Seikh, M., Seo, M., Seunarine, S., Myhr, P. A. Sevle, Shah, R., Shefali, S., Shimizu, N., Silva, M., Skrzypek, B., Smithers, B., Snihur, R., Soedingrekso, J., Søgaard, A., Soldin, D., Soldin, P., Sommani, G., Spannfellner, C., Spiczak, G. M., Spiering, C., Stachurska, J., Stamatikos, M., Stanev, T., Stezelberger, T., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Ter-Antonyan, S., Terliuk, A., Thiesmeyer, M., Thompson, W. G., Thwaites, J., Tilav, S., Tollefson, K., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Elorrieta, M. A. Unland, Upadhyay, A. K., Upshaw, K., Vaidyanathan, A., Valtonen-Mattila, N., Vandenbroucke, J., van Eijndhoven, N., Vannerom, D., van Santen, J., Vara, J., Varsi, F., Veitch-Michaelis, J., Venugopal, M., Vereecken, M., Carrasco, S. Vergara, Verpoest, S., Veske, D., Vijai, A., Walck, C., Wang, A., Weaver, C., Weigel, P., Weindl, A., Weldert, J., Wen, A. Y., Wendt, C., Werthebach, J., Weyrauch, M., Whitehorn, N., Wiebusch, C. H., Williams, D. R., Witthaus, L., Wolf, M., Wrede, G., Xu, X. W., Yanez, J. P., Yildizci, E., Yoshida, S., Young, R., Yu, F., Yu, S., Yuan, T., Zegarelli, A., Zhang, S., Zhang, Z., Zhelnin, P., Zilberman, P., Zimmerman, M., Drake, Pablo, Spira-Savett, Elizabeth, Lusen, Piatra, and Mori, Kaya
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
While the sources of the diffuse astrophysical neutrino flux detected by the IceCube Neutrino Observatory are still largely unknown, one of the promising methods used towards understanding this is investigating the potential temporal and spatial correlations between neutrino alerts and the electromagnetic radiation from blazars. We report on the multiwavelength target-of-opportunity observations of the blazar B3 2247+381, taken in response to an IceCube multiplet alert for a cluster of muon neutrino events compatible with the source location between May 20, 2022 and November 10, 2022. B3 2247+381 was not detected with VERITAS during this time period. The source was found to be in a low-flux state in the optical, ultraviolet and gamma-ray bands for the time interval corresponding to the neutrino event, but was detected in the hard X-ray band with NuSTAR during this period. We find the multiwavelength spectral energy distribution is well described using a simple one-zone leptonic synchrotron self-Compton radiation model. Moreover, assuming the neutrinos originate from hadronic processes within the jet, the neutrino flux would be accompanied by a photon flux from the cascade emission, and the integrated photon flux required in such a case would significantly exceed the total multiwavelength fluxes and the VERITAS upper limits presented here. The lack of flaring activity observed with VERITAS, combined with the low multiwavelength flux levels, and given the significance of the neutrino excess is at 3$\sigma$ level (uncorrected for trials), makes B3 2247+381 an unlikely source of the IceCube multiplet. We conclude that the neutrino excess is likely a background fluctuation., Comment: 26 pages, 5 figures. Accepted for publication in the Astrophysical Journal (ApJ)
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- 2025
23. K-dwarf Radius Inflation and a 10-Gyr Spin-down Clock Unveiled through Asteroseismology of HD~219134 from the Keck Planet Finder
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Li, Yaguang, Huber, Daniel, Ong, J. M. Joel, van Saders, Jennifer, Costa, R. R., Larsen, Jens Reersted, Basu, Sarbani, Bedding, Timothy R., Dai, Fei, Chontos, Ashley, Carmichael, Theron W., Hey, Daniel, Kjeldsen, Hans, Hon, Marc, Campante, Tiago L., Monteiro, Mário J. P. F. G., Lundkvist, Mia Sloth, Saunders, Nicholas, Isaacson, Howard, Howard, Andrew W., Gibson, Steven R., Halverson, Samuel, Rider, Kodi, Roy, Arpita, Baker, Ashley D., Edelstein, Jerry, Smith, Chris, Fulton, Benjamin J., and Walawender, Josh
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Astrophysics - Solar and Stellar Astrophysics ,Astrophysics - Earth and Planetary Astrophysics - Abstract
We present the first asteroseismic analysis of the K3\,V planet host HD~219134, based on four consecutive nights of radial velocities collected with the Keck Planet Finder. We applied Gold deconvolution to the power spectrum to disentangle modes from sidelobes in the spectral window, and extracted 25 mode frequencies with spherical degrees $0\leq\ell\leq3$. We derive the fundamental properties using five different evolutionary-modeling pipelines and report a mass of 0.763 $\pm$ 0.020 (stat) $\pm$ 0.007 (sys) M$_\odot$, a radius of 0.748 $\pm$ 0.007 (stat) $\pm$ 0.002 (sys) R$_\odot$, and an age of 10.151 $\pm$ 1.520 (stat) $\pm$ 0.810 (sys) Gyr. Compared to the interferometric radius 0.783 $\pm$ 0.005~R$_\odot$, the asteroseismic radius is 4\% smaller at the 4-$\sigma$ level -- a discrepancy not easily explained by known interferometric systematics, modeling assumptions on atmospheric boundary conditions and mixing lengths, magnetic fields, or tidal heating. HD~219134 is the first main-sequence star cooler than 5000~K with an asteroseismic age estimate and will serve as a critical calibration point for stellar spin-down relations. We show that existing calibrated prescriptions for angular momentum loss, incorporating weakened magnetic braking with asteroseismically constrained stellar parameters, accurately reproduce the observed rotation period. Additionally, we revised the masses and radii of the super-Earths in the system, which support their having Earth-like compositions. Finally, we confirm that the oscillation amplitude in radial velocity scales as $(L/M)^{1.5}$ in K dwarfs, in contrast to the $(L/M)^{0.7}$ relation observed in G dwarfs. These findings provide significant insights into the structure and angular momentum loss of K-type stars., Comment: 23 pages, 11 figures. submitted to AAS Journals. Comments welcome
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- 2025
24. Fast Direct: Query-Efficient Online Black-box Guidance for Diffusion-model Target Generation
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Tan, Kim Yong, Lyu, Yueming, Tsang, Ivor, and Ong, Yew-Soon
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Computer Science - Machine Learning ,Computer Science - Artificial Intelligence - Abstract
Guided diffusion-model generation is a promising direction for customizing the generation process of a pre-trained diffusion-model to address the specific downstream tasks. Existing guided diffusion models either rely on training of the guidance model with pre-collected datasets or require the objective functions to be differentiable. However, for most real-world tasks, the offline datasets are often unavailable, and their objective functions are often not differentiable, such as image generation with human preferences, molecular generation for drug discovery, and material design. Thus, we need an $\textbf{online}$ algorithm capable of collecting data during runtime and supporting a $\textbf{black-box}$ objective function. Moreover, the $\textbf{query efficiency}$ of the algorithm is also critical because the objective evaluation of the query is often expensive in the real-world scenarios. In this work, we propose a novel and simple algorithm, $\textbf{Fast Direct}$, for query-efficient online black-box target generation. Our Fast Direct builds a pseudo-target on the data manifold to update the noise sequence of the diffusion model with a universal direction, which is promising to perform query-efficient guided generation. Extensive experiments on twelve high-resolution ($\small {1024 \times 1024}$) image target generation tasks and six 3D-molecule target generation tasks show $\textbf{6}\times$ up to $\textbf{10}\times$ query efficiency improvement and $\textbf{11}\times$ up to $\textbf{44}\times$ query efficiency improvement, respectively. Our implementation is publicly available at: https://github.com/kimyong95/guide-stable-diffusion/tree/fast-direct
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- 2025
25. Do neonates hear what we measure? Assessing neonatal ward soundscapes at the neonates ears
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Lam, Bhan, Fan, Peijin Esther Monica, Tay, Yih Yann, Poon, Woei Bing, Ong, Zhen-Ting, Ooi, Kenneth, Gan, Woon-Seng, and Ang, Shin Yuh
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Electrical Engineering and Systems Science - Audio and Speech Processing ,Computer Science - Sound - Abstract
Acoustic guidelines for neonatal intensive care units (NICUs) aim to protect vulnerable neonates from noise-induced physiological harm. However, the lack of recognised international standards for measuring neonatal soundscapes has led to inconsistencies in instrumentation and microphone placement in existing literature, raising concerns about the relevance and effectiveness of these guidelines. This study addresses these gaps through long-term acoustic measurements in an operational NICU and a high-dependency ward. We investigate the influence of microphone positioning, bed placement, and ward layout on the assessment of NICU soundscapes. Beyond traditional A-weighted decibel metrics, this study evaluates C-weighted metrics for low-frequency noise, the occurrence of tonal sounds (e.g., alarms), and transient loud events known to disrupt neonates' sleep. Using linear mixed-effects models with aligned ranks transformation ANOVA (LME-ART-ANOVA), our results reveal significant differences in measured noise levels based on microphone placement, highlighting the importance of capturing sound as perceived directly at the neonate's ears. Additionally, bed position and ward layout significantly impact noise exposure, with a NICU bed position consistently exhibiting the highest sound levels across all (psycho)acoustic metrics. These findings support the adoption of binaural measurements along with the integration of additional (psycho)acoustic metrics, such as tonality and transient event occurrence rates, to reliably characterise the neonatal auditory experience., Comment: Accepted manuscript submitted to Building and Environment
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- 2025
26. Characterization of the Teledyne COSMOS Camera: A Large Format CMOS Image Sensor for Astronomy
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Layden, Christopher, Juneau, Jill, Pettersson, Gustav, Lourie, Nathan, Schneider, Benjamin, LaMarr, Beverly, Angile, F. Elio, Farag, Fadi, Luo, Michelle, Ong, Zhi Zheng, and Furesz, Gabor
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Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
The Teledyne COSMOS-66 is a next-generation CMOS camera designed for astronomical imaging, featuring a large-format sensor ($8120 \times 8120$ pixels, each $10 \mu m$), high quantum efficiency, high frame rates, and a correlated multi-sampling mode that achieves low read noise. We performed a suite of bench-top and on-sky tests to characterize this sensor and analyze its suitability for use in astronomical instruments. This paper presents measurements of linearity, conversion gain, read noise, dark current, quantum efficiency, image lag, and crosstalk. We found that the sensor exhibits nonlinear response below 5% of saturation. This nonlinearity is plausibly attributable to the trapping of electrons in each pixel. We developed and implemented a pixel-by-pixel nonlinearity correction, enabling accurate photometric measurements across the dynamic range. After implementing this correction, operating in the correlated multi-sampling mode, the sensor achieved an effective read noise of $2.9 e^-$ and dark current of $0.12 e^-/pix/s$ at $-25^\circ C$. The quantum efficiency exceeded 50% from 250 nm to 800 nm, peaking at 89% at 600 nm. We observed significant optical crosstalk between the pixels, likely caused by photoelectron diffusion. To demonstrate the sensor's astronomical performance, we mounted it on the WINTER 1m telescope at Palomar Observatory. These tests confirmed that the linearity calibration enables accurate stellar photometry and validated our measured noise levels. Overall, the COSMOS-66 delivers similar noise performance to large-format CCDs, with higher frame rates and relaxed cooling requirements. If pixel design improvements are made to mitigate the nonlinearity and crosstalk, then the camera may combine the advantages of low-noise CMOS image sensors with the integration simplicity of large-format CCDs, broadening its utility to a host of astronomical science cases., Comment: 45 pages, 16 figures, submitted to JATIS
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- 2025
27. Constitutional Classifiers: Defending against Universal Jailbreaks across Thousands of Hours of Red Teaming
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Sharma, Mrinank, Tong, Meg, Mu, Jesse, Wei, Jerry, Kruthoff, Jorrit, Goodfriend, Scott, Ong, Euan, Peng, Alwin, Agarwal, Raj, Anil, Cem, Askell, Amanda, Bailey, Nathan, Benton, Joe, Bluemke, Emma, Bowman, Samuel R., Christiansen, Eric, Cunningham, Hoagy, Dau, Andy, Gopal, Anjali, Gilson, Rob, Graham, Logan, Howard, Logan, Kalra, Nimit, Lee, Taesung, Lin, Kevin, Lofgren, Peter, Mosconi, Francesco, O'Hara, Clare, Olsson, Catherine, Petrini, Linda, Rajani, Samir, Saxena, Nikhil, Silverstein, Alex, Singh, Tanya, Sumers, Theodore, Tang, Leonard, Troy, Kevin K., Weisser, Constantin, Zhong, Ruiqi, Zhou, Giulio, Leike, Jan, Kaplan, Jared, and Perez, Ethan
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Computer Science - Computation and Language ,Computer Science - Artificial Intelligence ,Computer Science - Cryptography and Security ,Computer Science - Machine Learning - Abstract
Large language models (LLMs) are vulnerable to universal jailbreaks-prompting strategies that systematically bypass model safeguards and enable users to carry out harmful processes that require many model interactions, like manufacturing illegal substances at scale. To defend against these attacks, we introduce Constitutional Classifiers: safeguards trained on synthetic data, generated by prompting LLMs with natural language rules (i.e., a constitution) specifying permitted and restricted content. In over 3,000 estimated hours of red teaming, no red teamer found a universal jailbreak that could extract information from an early classifier-guarded LLM at a similar level of detail to an unguarded model across most target queries. On automated evaluations, enhanced classifiers demonstrated robust defense against held-out domain-specific jailbreaks. These classifiers also maintain deployment viability, with an absolute 0.38% increase in production-traffic refusals and a 23.7% inference overhead. Our work demonstrates that defending against universal jailbreaks while maintaining practical deployment viability is tractable.
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- 2025
28. Reward Prediction Error Prioritisation in Experience Replay: The RPE-PER Method
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Yamani, Hoda, Xing, Yuning, Ong, Lee Violet C., MacDonald, Bruce A., and Williams, Henry
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Computer Science - Machine Learning ,Computer Science - Robotics - Abstract
Reinforcement Learning algorithms aim to learn optimal control strategies through iterative interactions with an environment. A critical element in this process is the experience replay buffer, which stores past experiences, allowing the algorithm to learn from a diverse range of interactions rather than just the most recent ones. This buffer is especially essential in dynamic environments with limited experiences. However, efficiently selecting high-value experiences to accelerate training remains a challenge. Drawing inspiration from the role of reward prediction errors (RPEs) in biological systems, where they are essential for adaptive behaviour and learning, we introduce Reward Predictive Error Prioritised Experience Replay (RPE-PER). This novel approach prioritises experiences in the buffer based on RPEs. Our method employs a critic network, EMCN, that predicts rewards in addition to the Q-values produced by standard critic networks. The discrepancy between these predicted and actual rewards is computed as RPE and utilised as a signal for experience prioritisation. Experimental evaluations across various continuous control tasks demonstrate RPE-PER's effectiveness in enhancing the learning speed and performance of off-policy actor-critic algorithms compared to baseline approaches., Comment: This paper was accepted for presentation at the 2024 Australasian Conference on Robotics and Automation (ACRA 2024). It consists of 10 pages, including four figures and two tables
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- 2025
29. A foundation model for human-AI collaboration in medical literature mining
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Wang, Zifeng, Cao, Lang, Jin, Qiao, Chan, Joey, Wan, Nicholas, Afzali, Behdad, Cho, Hyun-Jin, Choi, Chang-In, Emamverdi, Mehdi, Gill, Manjot K., Kim, Sun-Hyung, Li, Yijia, Liu, Yi, Ong, Hanley, Rousseau, Justin, Sheikh, Irfan, Wei, Jenny J., Xu, Ziyang, Zallek, Christopher M., Kim, Kyungsang, Peng, Yifan, Lu, Zhiyong, and Sun, Jimeng
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Computer Science - Computation and Language - Abstract
Systematic literature review is essential for evidence-based medicine, requiring comprehensive analysis of clinical trial publications. However, the application of artificial intelligence (AI) models for medical literature mining has been limited by insufficient training and evaluation across broad therapeutic areas and diverse tasks. Here, we present LEADS, an AI foundation model for study search, screening, and data extraction from medical literature. The model is trained on 633,759 instruction data points in LEADSInstruct, curated from 21,335 systematic reviews, 453,625 clinical trial publications, and 27,015 clinical trial registries. We showed that LEADS demonstrates consistent improvements over four cutting-edge generic large language models (LLMs) on six tasks. Furthermore, LEADS enhances expert workflows by providing supportive references following expert requests, streamlining processes while maintaining high-quality results. A study with 16 clinicians and medical researchers from 14 different institutions revealed that experts collaborating with LEADS achieved a recall of 0.81 compared to 0.77 experts working alone in study selection, with a time savings of 22.6%. In data extraction tasks, experts using LEADS achieved an accuracy of 0.85 versus 0.80 without using LEADS, alongside a 26.9% time savings. These findings highlight the potential of specialized medical literature foundation models to outperform generic models, delivering significant quality and efficiency benefits when integrated into expert workflows for medical literature mining.
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- 2025
30. TOPLOC: A Locality Sensitive Hashing Scheme for Trustless Verifiable Inference
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Ong, Jack Min, Di Ferrante, Matthew, Pazdera, Aaron, Garner, Ryan, Jaghouar, Sami, Basra, Manveer, and Hagemann, Johannes
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Computer Science - Cryptography and Security ,Computer Science - Distributed, Parallel, and Cluster Computing - Abstract
Large language models (LLMs) have proven to be very capable, but access to the best models currently rely on inference providers which introduces trust challenges -- how can we be sure that the provider is using the model configuration they claim? We propose TOPLOC, a novel method for verifiable inference that addresses this problem. TOPLOC leverages a compact locality sensitive hashing mechanism for intermediate activations which can detect unauthorized modifications to models, prompts, or precision with 100% accuracy, achieving no false positives or negatives in our empirical evaluations. Our approach is robust across diverse hardware configurations, GPU types, and algebraic reorderings, which allows for validation speeds significantly faster than the original inference. By introducing a polynomial encoding scheme, TOPLOC minimizes memory overhead of the generated commits by $1000\times$, requiring only 258 bytes of storage per 32 new tokens compared to the 262KB requirement of storing the token embeddings directly for Llama-3.1-8B-Instruct. Our method empowers users to verify LLM inference computations efficiently, fostering greater trust and transparency in open ecosystems and lays a foundation for decentralized and verifiable AI services., Comment: 18 pages, 13 tables, 5 figures
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- 2025
31. Unconventional Superconducting Phase Diagram of Monolayer WTe2
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Song, Tiancheng, Jia, Yanyu, Yu, Guo, Tang, Yue, Uzan, Ayelet J., Zheng, Zhaoyi Joy, Guan, Haosen, Onyszczak, Michael, Singha, Ratnadwip, Gui, Xin, Watanabe, Kenji, Taniguchi, Takashi, Cava, Robert J., Schoop, Leslie M., Ong, N. P., and Wu, Sanfeng
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Condensed Matter - Mesoscale and Nanoscale Physics ,Condensed Matter - Strongly Correlated Electrons ,Condensed Matter - Superconductivity - Abstract
The existence of a quantum critical point (QCP) and fluctuations around it are believed to be important for understanding the phase diagram in unconventional superconductors such as cuprates, iron pnictides, and heavy fermion superconductors. However, the QCP is usually buried deep within the superconducting dome and is difficult to investigate. The connection between quantum critical fluctuations and superconductivity remains an outstanding problem in condensed matter. Here combining both electrical transport and Nernst experiments, we explicitly demonstrate the onset of superconductivity at an unconventional QCP in gate-tuned monolayer tungsten ditelluride (WTe2), with features incompatible with the conventional Bardeen-Cooper-Schrieffer (BCS) scenario. The results lead to a novel superconducting phase diagram that is distinguished from other known superconductors. Two distinct gate-tuned quantum phase transitions are observed at the ends of the superconducting dome. We find that quantum fluctuations around the QCP of the underdoped regime are essential for understanding how the monolayer superconductivity is established. The unconventional phase diagram we report here illustrates a previously unknown relation between superconductivity and QCP.
- Published
- 2025
32. ESGSenticNet: A Neurosymbolic Knowledge Base for Corporate Sustainability Analysis
- Author
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Ong, Keane, Mao, Rui, Xing, Frank, Satapathy, Ranjan, Sulaeman, Johan, Cambria, Erik, and Mengaldo, Gianmarco
- Subjects
Computer Science - Computation and Language - Abstract
Evaluating corporate sustainability performance is essential to drive sustainable business practices, amid the need for a more sustainable economy. However, this is hindered by the complexity and volume of corporate sustainability data (i.e. sustainability disclosures), not least by the effectiveness of the NLP tools used to analyse them. To this end, we identify three primary challenges - immateriality, complexity, and subjectivity, that exacerbate the difficulty of extracting insights from sustainability disclosures. To address these issues, we introduce ESGSenticNet, a publicly available knowledge base for sustainability analysis. ESGSenticNet is constructed from a neurosymbolic framework that integrates specialised concept parsing, GPT-4o inference, and semi-supervised label propagation, together with a hierarchical taxonomy. This approach culminates in a structured knowledge base of 44k knowledge triplets - ('halve carbon emission', supports, 'emissions control'), for effective sustainability analysis. Experiments indicate that ESGSenticNet, when deployed as a lexical method, more effectively captures relevant and actionable sustainability information from sustainability disclosures compared to state of the art baselines. Besides capturing a high number of unique ESG topic terms, ESGSenticNet outperforms baselines on the ESG relatedness and ESG action orientation of these terms by 26% and 31% respectively. These metrics describe the extent to which topic terms are related to ESG, and depict an action toward ESG. Moreover, when deployed as a lexical method, ESGSenticNet does not require any training, possessing a key advantage in its simplicity for non-technical stakeholders.
- Published
- 2025
33. Generative Multi-Form Bayesian Optimization
- Author
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Guo, Zhendong, Liu, Haitao, Ong, Yew-Soon, Qu, Xinghua, Zhang, Yuzhe, and Zheng, Jianmin
- Subjects
Computer Science - Computational Engineering, Finance, and Science - Abstract
Many real-world problems, such as airfoil design, involve optimizing a black-box expensive objective function over complex structured input space (e.g., discrete space or non-Euclidean space). By mapping the complex structured input space into a latent space of dozens of variables, a two-stage procedure labeled as generative model based optimization (GMO) in this paper, shows promise in solving such problems. However, the latent dimension of GMO is hard to determine, which may trigger the conflicting issue between desirable solution accuracy and convergence rate. To address the above issue, we propose a multi-form GMO approach, namely generative multi-form optimization (GMFoO), which conducts optimization over multiple latent spaces simultaneously to complement each other. More specifically, we devise a generative model which promotes positive correlation between latent spaces to facilitate effective knowledge transfer in GMFoO. And further, by using Bayesian optimization (BO) as the optimizer, we propose two strategies to exchange information between these latent spaces continuously. Experimental results are presented on airfoil and corbel design problems and an area maximization problem as well to demonstrate that our proposed GMFoO converges to better designs on a limited computational budget.
- Published
- 2025
- Full Text
- View/download PDF
34. Co-Learning Bayesian Optimization
- Author
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Guo, Zhendong, Ong, Yew-Soon, He, Tiantian, and Liu, Haitao
- Subjects
Computer Science - Machine Learning ,Statistics - Machine Learning - Abstract
Bayesian optimization (BO) is well known to be sample-efficient for solving black-box problems. However, the BO algorithms can sometimes get stuck in suboptimal solutions even with plenty of samples. Intrinsically, such suboptimal problem of BO can attribute to the poor surrogate accuracy of the trained Gaussian process (GP), particularly that in the regions where the optimal solutions locate. Hence, we propose to build multiple GP models instead of a single GP surrogate to complement each other and thus resolving the suboptimal problem of BO. Nevertheless, according to the bias-variance tradeoff equation, the individual prediction errors can increase when increasing the diversity of models, which may lead to even worse overall surrogate accuracy. On the other hand, based on the theory of Rademacher complexity, it has been proved that exploiting the agreement of models on unlabeled information can help to reduce the complexity of the hypothesis space, and therefore achieving the required surrogate accuracy with fewer samples. Such value of model agreement has been extensively demonstrated for co-training style algorithms to boost model accuracy with a small portion of samples. Inspired by the above, we propose a novel BO algorithm labeled as co-learning BO (CLBO), which exploits both model diversity and agreement on unlabeled information to improve the overall surrogate accuracy with limited samples, and therefore achieving more efficient global optimization. Through tests on five numerical toy problems and three engineering benchmarks, the effectiveness of proposed CLBO has been well demonstrated.
- Published
- 2025
- Full Text
- View/download PDF
35. An in-depth study of Gamma rays from the Starburst Galaxy M 82 with VERITAS
- Author
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Acharyya, Atreya, Adams, Colin B., Bangale, Priyadarshini, Bartkoske, Joshua T., Benbow, Wystan, Chen, Yu, Christiansen, Jodi L., Chromey, Alisha J., Duerr, Anne, Errando, Manel, Godoy, Miguel E., Falcone, Abe, Feldman, Sydney, Feng, Qi, Foote, Juniper, Fortson, Lucy, Furniss, Amy, Hanlon, William, Hanna, David, Hervet, Olivier, Hinrichs, Claire E., Holder, Jamie, Humensky, Thomas B., Jin, Weidong, Johnson, Madalyn N., Kaaret, Philip, Kertzman, Mary, Kherlakian, Maria, Kieda, David, Kleiner, Tobias K., Korzoun, Nikolas, Krennrich, Frank, Kumar, Sajan, Lang, Mark J., Lundy, Matthew, Maier, Gernot, Millard, Matthew J., Mooney, Connor L., Moriarty, Patrick, Mukherjee, Reshmi, Ning, Wenmeng, Brien, Stephan Ó, Ong, Rene A., Pohl, Martin, Pueschel, Elisa, Quinn, John, Rabinowitz, Pazit L., Ragan, Kenneth J., Reynolds, Paul T., Ribeiro, Deivid, Roache, Emmet, Sadeh, Iftach, Saha, Lab, Santander, Marcos, Sembroski, Glenn H., Shang, Ruo, Splettstoesser, Megan, Talluri, Anjana K., Tucci, James V., Vassiliev, Vladimir V., Williams, David A., Wong, Samantha L., and Woo, Jooyun
- Subjects
Astrophysics - High Energy Astrophysical Phenomena - Abstract
Assuming Galactic cosmic rays originate in supernovae and the winds of massive stars, starburst galaxies should produce very-high-energy (VHE; E$>$100 GeV) gamma-ray emission via the interaction of their copious quantities of cosmic rays with the large reservoirs of dense gas within the galaxies. Such VHE emission was detected by VERITAS from the starburst galaxy M 82 in 2008-09. An extensive, multi-year campaign followed these initial observations, yielding a total of 254 h of good quality VERITAS data on M 82. Leveraging modern analysis techniques and the larger exposure, these VERITAS data show a more statistically significant VHE signal ($\sim$6.5 standard deviations ($\sigma$)). The corresponding photon spectrum is well fit by a power law ($\Gamma = 2.3 \pm 0.3_{stat} \pm0.2_{sys}$) and the observed integral flux is F($>$450 GeV) = $(3.2 \pm0.6_{stat} \pm 0.6_{sys}) \times 10^{-13}~\mathrm{cm^{-2}~s}^{-1}$, or $\sim$0.4\% of the Crab Nebula flux above the same energy threshold. The improved VERITAS measurements, when combined with various multi-wavelength data, enable modeling of the underlying emission and transport processes. A purely leptonic scenario is found to be a poor representation of the gamma-ray spectral energy distribution (SED). A lepto-hadronic scenario with cosmic rays following a power-law spectrum in momentum (index $s\simeq 2.25$), and with significant bremsstrahlung below $1$~GeV, provides a good match to the observed SED. The synchrotron emission from the secondary electrons indicates that efficient non-radiative losses of cosmic-ray electrons may be related to advective escape from the starburst core., Comment: 15 pages, 7 figures; Accepted for the publication in The Astrophysical Journal (ApJ)
- Published
- 2025
36. Dynamic Multimodal Sentiment Analysis: Leveraging Cross-Modal Attention for Enabled Classification
- Author
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Lee, Hui, Suniljit, Singh, and Ong, Yong Siang
- Subjects
Computer Science - Computation and Language ,Computer Science - Machine Learning - Abstract
This paper explores the development of a multimodal sentiment analysis model that integrates text, audio, and visual data to enhance sentiment classification. The goal is to improve emotion detection by capturing the complex interactions between these modalities, thereby enabling more accurate and nuanced sentiment interpretation. The study evaluates three feature fusion strategies -- late stage fusion, early stage fusion, and multi-headed attention -- within a transformer-based architecture. Experiments were conducted using the CMU-MOSEI dataset, which includes synchronized text, audio, and visual inputs labeled with sentiment scores. Results show that early stage fusion significantly outperforms late stage fusion, achieving an accuracy of 71.87\%, while the multi-headed attention approach offers marginal improvement, reaching 72.39\%. The findings suggest that integrating modalities early in the process enhances sentiment classification, while attention mechanisms may have limited impact within the current framework. Future work will focus on refining feature fusion techniques, incorporating temporal data, and exploring dynamic feature weighting to further improve model performance.
- Published
- 2025
37. Physics-Informed Neuro-Evolution (PINE): A Survey and Prospects
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Wong, Jian Cheng, Gupta, Abhishek, Ooi, Chin Chun, Chiu, Pao-Hsiung, Liu, Jiao, and Ong, Yew-Soon
- Subjects
Computer Science - Neural and Evolutionary Computing ,Computer Science - Computational Engineering, Finance, and Science ,Computer Science - Machine Learning - Abstract
Deep learning models trained on finite data lack a complete understanding of the physical world. On the other hand, physics-informed neural networks (PINNs) are infused with such knowledge through the incorporation of mathematically expressible laws of nature into their training loss function. By complying with physical laws, PINNs provide advantages over purely data-driven models in limited-data regimes. This feature has propelled them to the forefront of scientific machine learning, a domain characterized by scarce and costly data. However, the vision of accurate physics-informed learning comes with significant challenges. This review examines PINNs for the first time in terms of model optimization and generalization, shedding light on the need for new algorithmic advances to overcome issues pertaining to the training speed, precision, and generalizability of today's PINN models. Of particular interest are the gradient-free methods of neuroevolution for optimizing the uniquely complex loss landscapes arising in PINN training. Methods synergizing gradient descent and neuroevolution for discovering bespoke neural architectures and balancing multiple conflicting terms in physics-informed learning objectives are positioned as important avenues for future research. Yet another exciting track is to cast neuroevolution as a meta-learner of generalizable PINN models., Comment: 20 pages, 8 figures, 1 table
- Published
- 2025
38. How quantum selection rules influence the magneto-optical effects of driven, ultrafast magnetization dynamics
- Author
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Elhanoty, Mohamed F., Eriksson, Olle, Ong, Chin Shen, and Grånäs, Oscar
- Subjects
Condensed Matter - Materials Science - Abstract
Ultrafast magnetization dynamics driven by ultrashort pump lasers is typically explained by changes in electronic populations and scattering pathways of excited conduction electrons. This conventional approach overlooks the fundamental role of quantum mechanical selection rules, governing transitions from core states to the conduction band, that forms the key method of the probing step in these experiments. By employing fully ab initio time-dependent density functional theory, we reveal that these selection rules profoundly influence the interpretation of ultrafast spin dynamics at specific probe energies. Our analysis for hcp Co and fcc Ni at the M edge demonstrates that the transient dynamics, as revealed in pump-probe experiments, arise from a complex interplay of optical excitations of the M shell. Taking into account the selection rules and conduction electron spin flips, this leads to highly energy-dependent dynamics. These findings address longstanding discrepancies in experimental TMOKE measurements and show that only through meticulous consideration of matrix elements at the probe stage, can one ensure that magnetization dynamics is revealed in its true nature, instead of being muddled by artifacts arising from the choice of probe energy.
- Published
- 2025
39. Resolving an Asteroseismic Catastrophe: Structural Diagnostics from p-mode Phase Functions off the Main Sequence
- Author
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Ong, J. M. Joel, Lindsay, Christopher J., Reyes, Claudia, Stello, Dennis, and Roxburgh, Ian W.
- Subjects
Astrophysics - Solar and Stellar Astrophysics - Abstract
On the main sequence, the asteroseismic small frequency separation $\delta\nu_{02}$ between radial and quadrupole p-modes is customarily interpreted to be a direct diagnostic of internal structure. Such an interpretation is based on a well-known integral estimator relating $\delta\nu_{02}$ to a radially-averaged sound-speed gradient. However, this estimator fails, catastrophically, when evaluated on structural models of red giants: their small separations must therefore be interpreted differently. We derive a single expression which both reduces to the classical estimator when applied to main-sequence stellar models, yet reproduces the qualitative features of the small separation for stellar models of very evolved red giants. This expression indicates that the small separations of red giants scale primarily with their global seismic properties as $\delta\nu_{02} \propto \Delta\nu^2/\nu_\mathrm{max}$, rather than being in any way sensitive to their internal structure. Departures from this asymptotic behaviour, during the transition from the main-sequence to red giant regimes, have been recently reported in open-cluster Christensen-Dalsgaard (C-D) diagrams from K2 mission data. Investigating them in detail, we demonstrate that they occur when the convective envelope boundary passes a specific acoustic distance -- roughly a third of a wavelength at $\nu_\mathrm{max}$ -- from the centre of the star, at which point radial modes become maximally sensitive to the position of the boundary. The shape of the corresponding features on $\epsilon_p$ and C-D (or $r_{02}$) diagrams may be useful in constraining the nature of convective boundary mixing, in the context of undershooting beneath a convective envelope., Comment: 14 pages, 8 figures. Accepted for publication in The Astrophysical Journal
- Published
- 2025
40. Open Problems in Machine Unlearning for AI Safety
- Author
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Barez, Fazl, Fu, Tingchen, Prabhu, Ameya, Casper, Stephen, Sanyal, Amartya, Bibi, Adel, O'Gara, Aidan, Kirk, Robert, Bucknall, Ben, Fist, Tim, Ong, Luke, Torr, Philip, Lam, Kwok-Yan, Trager, Robert, Krueger, David, Mindermann, Sören, Hernandez-Orallo, José, Geva, Mor, and Gal, Yarin
- Subjects
Computer Science - Machine Learning ,Computer Science - Artificial Intelligence ,Computer Science - Computers and Society - Abstract
As AI systems become more capable, widely deployed, and increasingly autonomous in critical areas such as cybersecurity, biological research, and healthcare, ensuring their safety and alignment with human values is paramount. Machine unlearning -- the ability to selectively forget or suppress specific types of knowledge -- has shown promise for privacy and data removal tasks, which has been the primary focus of existing research. More recently, its potential application to AI safety has gained attention. In this paper, we identify key limitations that prevent unlearning from serving as a comprehensive solution for AI safety, particularly in managing dual-use knowledge in sensitive domains like cybersecurity and chemical, biological, radiological, and nuclear (CBRN) safety. In these contexts, information can be both beneficial and harmful, and models may combine seemingly harmless information for harmful purposes -- unlearning this information could strongly affect beneficial uses. We provide an overview of inherent constraints and open problems, including the broader side effects of unlearning dangerous knowledge, as well as previously unexplored tensions between unlearning and existing safety mechanisms. Finally, we investigate challenges related to evaluation, robustness, and the preservation of safety features during unlearning. By mapping these limitations and open challenges, we aim to guide future research toward realistic applications of unlearning within a broader AI safety framework, acknowledging its limitations and highlighting areas where alternative approaches may be required.
- Published
- 2025
41. Attending To Syntactic Information In Biomedical Event Extraction Via Graph Neural Networks
- Author
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Noravesh, Farshad, Haffari, Reza, Fang, Ong Huey, Soon, Layki, Rajalana, Sailaja, and Pal, Arghya
- Subjects
Computer Science - Computation and Language - Abstract
Many models are proposed in the literature on biomedical event extraction(BEE). Some of them use the shortest dependency path(SDP) information to represent the argument classification task. There is an issue with this representation since even missing one word from the dependency parsing graph may totally change the final prediction. To this end, the full adjacency matrix of the dependency graph is used to embed individual tokens using a graph convolutional network(GCN). An ablation study is also done to show the effect of the dependency graph on the overall performance. The results show a significant improvement when dependency graph information is used. The proposed model slightly outperforms state-of-the-art models on BEE over different datasets., Comment: 6 figures, 4 tables
- Published
- 2025
42. The novel quinoline derivative SKA-346 as a KCa3.1 channel selective activator.
- Author
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Wong, Brandon, Shim, Heesung, Goay, Stephanie, Ong, Seow, Muhammad Taib, Nur, Chai, Kelila, Lim, Kerry, Huang, Dachuan, Ong, Choon, Vaiyapuri, Thamil, Cheah, Yeong, Wang, Yulan, Wulff, Heike, Webster, Richard, Shelat, Vishalkumar, and Verma, Navin
- Abstract
The calcium-activated KCa3.1 channel plays a crucial role in T-cell immune response. Genetic manipulation of T-cells to upregulate the expression of K+ channels has been shown to boost T-cell cytotoxicity in cancer. Here, we aimed to identify and characterize an activator that would augment KCa3.1 currents without affecting other channels. We synthesized five quinoline derivatives and used electrophysiology to screen them on KCa3.1 and a panel of 14 other ion channels. One quinoline derivative, SKA-346, activated KCa3.1 with an EC50 of 1.9 μM and showed selectivity against the other channels. In silico analysis using RosettaLigand and GLIDE demonstrated a well-converged pose of SKA-346 in a binding pocket at the interface between the calmodulin N-lobe and the S45A helix in the S4-S5 linker of the KCa3.1 channel. SKA-346 (30 mg kg-1), tolerated by mice after intra-peritoneal administration, exhibited a peak plasma concentration of 6.29 μg mL-1 (29.2 μM) at 15 min and a circulating half-life (t 1/2) of 2.8 h. SKA-346 could serve as a template for the development of more potent KCa3.1 activators to enhance T-cell cytotoxicity in cancer.
- Published
- 2024
43. Signatures of Core-Envelope Rotational Misalignment in the Mixed-Mode Asteroseismology of Kepler-56
- Author
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Ong, J. M. Joel
- Subjects
Astrophysics - Solar and Stellar Astrophysics ,Astrophysics - Earth and Planetary Astrophysics - Abstract
Existing asteroseismic rotational measurements assume that stars rotate around a single axis. However, tidal torques from misaligned companions, or their possible engulfment, may bring the rotational axis of a star's envelope out of alignment with its core, breaking azimuthal symmetry. I derive perturbative expressions for asteroseismic signatures of such hitherto unexamined rotational configurations, under the ``shellular approximation'' of constant rotation rates on radially stratified mass shells. In the aligned case, the distribution of power between multiplet components is determined by the inclination of the rotational axis; radial differential misalignment causes this to vary from multiplet to multiplet. I examine in particular detail the phenomenology of gravitoacoustic mixed modes as seen in evolved sub- and red giants, where near-resonance avoided crossings may break geometrical degeneracies. Upon applying the revised asteroseismic observational methodology that results from this theoretical discussion to revisit Kepler-56 -- a red giant with a misaligned planetary system -- I find that its core and envelope rotate around different rotational axes. While the rotational axis of its core is indeed misaligned from the orbit normal of its transiting planets (consistently with earlier studies), its envelope's rotational axis is close to lying in the sky plane, and may well be aligned with them. More detailed asteroseismic modelling, and spectroscopic follow-up, will be required to fully elucidate the full spin-orbit geometry of the Kepler-56 system, and potentially discriminate between hypotheses for how it formed., Comment: 19 pages, 7 figures, 2 tables. Accepted for publication in The Astrophysical Journal
- Published
- 2024
44. Real-world Deployment and Evaluation of PErioperative AI CHatbot (PEACH) -- a Large Language Model Chatbot for Perioperative Medicine
- Author
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Ke, Yu He, Jin, Liyuan, Elangovan, Kabilan, Ong, Bryan Wen Xi, Oh, Chin Yang, Sim, Jacqueline, Loh, Kenny Wei-Tsen, Soh, Chai Rick, Cheng, Jonathan Ming Hua, Lee, Aaron Kwang Yang, Ting, Daniel Shu Wei, Liu, Nan, and Abdullah, Hairil Rizal
- Subjects
Computer Science - Artificial Intelligence - Abstract
Large Language Models (LLMs) are emerging as powerful tools in healthcare, particularly for complex, domain-specific tasks. This study describes the development and evaluation of the PErioperative AI CHatbot (PEACH), a secure LLM-based system integrated with local perioperative guidelines to support preoperative clinical decision-making. PEACH was embedded with 35 institutional perioperative protocols in the secure Claude 3.5 Sonet LLM framework within Pair Chat (developed by Singapore Government) and tested in a silent deployment with real-world data. Accuracy, safety, and usability were assessed. Deviations and hallucinations were categorized based on potential harm, and user feedback was evaluated using the Technology Acceptance Model (TAM). Updates were made after the initial silent deployment to amend one protocol. In 240 real-world clinical iterations, PEACH achieved a first-generation accuracy of 97.5% (78/80) and an overall accuracy of 96.7% (232/240) across three iterations. The updated PEACH demonstrated improved accuracy of 97.9% (235/240), with a statistically significant difference from the null hypothesis of 95% accuracy (p = 0.018, 95% CI: 0.952-0.991). Minimal hallucinations and deviations were observed (both 1/240 and 2/240, respectively). Clinicians reported that PEACH expedited decisions in 95% of cases, and inter-rater reliability ranged from kappa 0.772-0.893 within PEACH and 0.610-0.784 among attendings. PEACH is an accurate, adaptable tool that enhances consistency and efficiency in perioperative decision-making. Future research should explore its scalability across specialties and its impact on clinical outcomes., Comment: 21 pages, 3 figures, 1 graphical abstract
- Published
- 2024
45. FedRLHF: A Convergence-Guaranteed Federated Framework for Privacy-Preserving and Personalized RLHF
- Author
-
Fan, Flint Xiaofeng, Tan, Cheston, Ong, Yew-Soon, Wattenhofer, Roger, and Ooi, Wei-Tsang
- Subjects
Computer Science - Machine Learning ,Computer Science - Artificial Intelligence ,Computer Science - Cryptography and Security ,I.2.11 - Abstract
In the era of increasing privacy concerns and demand for personalized experiences, traditional Reinforcement Learning with Human Feedback (RLHF) frameworks face significant challenges due to their reliance on centralized data. We introduce Federated Reinforcement Learning with Human Feedback (FedRLHF), a novel framework that decentralizes the RLHF process. FedRLHF enables collaborative policy learning across multiple clients without necessitating the sharing of raw data or human feedback, thereby ensuring robust privacy preservation. Leveraging federated reinforcement learning, each client integrates human feedback locally into their reward functions and updates their policies through personalized RLHF processes. We establish rigorous theoretical foundations for FedRLHF, providing convergence guarantees, and deriving sample complexity bounds that scale efficiently with the number of clients. Empirical evaluations on the MovieLens and IMDb datasets demonstrate that FedRLHF not only preserves user privacy but also achieves performance on par with centralized RLHF, while enhancing personalization across diverse client environments., Comment: Accepted to AAMAS 2025. This preprint represents the full version of the paper, including all proofs, experimental details, and additional discussions
- Published
- 2024
46. Spectrum-based Modality Representation Fusion Graph Convolutional Network for Multimodal Recommendation
- Author
-
Ong, Rongqing Kenneth and Khong, Andy W. H.
- Subjects
Computer Science - Information Retrieval ,Computer Science - Multimedia - Abstract
Incorporating multi-modal features as side information has recently become a trend in recommender systems. To elucidate user-item preferences, recent studies focus on fusing modalities via concatenation, element-wise sum, or attention mechanisms. Despite having notable success, existing approaches do not account for the modality-specific noise encapsulated within each modality. As a result, direct fusion of modalities will lead to the amplification of cross-modality noise. Moreover, the variation of noise that is unique within each modality results in noise alleviation and fusion being more challenging. In this work, we propose a new Spectrum-based Modality Representation (SMORE) fusion graph recommender that aims to capture both uni-modal and fusion preferences while simultaneously suppressing modality noise. Specifically, SMORE projects the multi-modal features into the frequency domain and leverages the spectral space for fusion. To reduce dynamic contamination that is unique to each modality, we introduce a filter to attenuate and suppress the modality noise adaptively while capturing the universal modality patterns effectively. Furthermore, we explore the item latent structures by designing a new multi-modal graph learning module to capture associative semantic correlations and universal fusion patterns among similar items. Finally, we formulate a new modality-aware preference module, which infuses behavioral features and balances the uni- and multi-modal features for precise preference modeling. This empowers SMORE with the ability to infer both user modality-specific and fusion preferences more accurately. Experiments on three real-world datasets show the efficacy of our proposed model. The source code for this work has been made publicly available at https://github.com/kennethorq/SMORE., Comment: Accepted to ACM Web Search and Data Mining (WSDM) 2025
- Published
- 2024
- Full Text
- View/download PDF
47. The Digital Ecosystem of Beliefs: does evolution favour AI over humans?
- Author
-
Bossens, David M., Feng, Shanshan, and Ong, Yew-Soon
- Subjects
Computer Science - Artificial Intelligence ,Computer Science - Multiagent Systems ,Computer Science - Neural and Evolutionary Computing - Abstract
As AI systems are integrated into social networks, there are AI safety concerns that AI-generated content may dominate the web, e.g. in popularity or impact on beliefs. To understand such questions, this paper proposes the Digital Ecosystem of Beliefs (Digico), the first evolutionary framework for controlled experimentation with multi-population interactions in simulated social networks. The framework models a population of agents which change their messaging strategies due to evolutionary updates following a Universal Darwinism approach, interact via messages, influence each other's beliefs through dynamics based on a contagion model, and maintain their beliefs through cognitive Lamarckian inheritance. Initial experiments with an abstract implementation of Digico show that: a) when AIs have faster messaging, evolution, and more influence in the recommendation algorithm, they get 80% to 95% of the views, depending on the size of the influence benefit; b) AIs designed for propaganda can typically convince 50% of humans to adopt extreme beliefs, and up to 85% when agents believe only a limited number of channels; c) a penalty for content that violates agents' beliefs reduces propaganda effectiveness by up to 8%. We further discuss implications for control (e.g. legislation) and Digico as a means of studying evolutionary principles.
- Published
- 2024
48. Indirect Query Bayesian Optimization with Integrated Feedback
- Author
-
Zhang, Mengyan, Bouabid, Shahine, Ong, Cheng Soon, Flaxman, Seth, and Sejdinovic, Dino
- Subjects
Computer Science - Machine Learning - Abstract
We develop the framework of Indirect Query Bayesian Optimization (IQBO), a new class of Bayesian optimization problems where the integrated feedback is given via a conditional expectation of the unknown function $f$ to be optimized. The underlying conditional distribution can be unknown and learned from data. The goal is to find the global optimum of $f$ by adaptively querying and observing in the space transformed by the conditional distribution. This is motivated by real-world applications where one cannot access direct feedback due to privacy, hardware or computational constraints. We propose the Conditional Max-Value Entropy Search (CMES) acquisition function to address this novel setting, and propose a hierarchical search algorithm to address the multi-resolution setting and improve the computational efficiency. We show regret bounds for our proposed methods and demonstrate the effectiveness of our approaches on simulated optimization tasks., Comment: Preliminary work. Under review
- Published
- 2024
49. Probability and Angelic Nondeterminism with Multiset Semantics
- Author
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Ong, Shawn, Ma, Stephanie, and Kozen, Dexter
- Subjects
Computer Science - Logic in Computer Science ,Computer Science - Formal Languages and Automata Theory ,Computer Science - Programming Languages - Abstract
We introduce a version of probabilistic Kleene algebra with angelic nondeterminism and a corresponding class of automata. Our approach implements semantics via distributions over multisets in order to overcome theoretical barriers arising from the lack of a distributive law between the powerset and Giry monads. We produce a full Kleene theorem and a coalgebraic theory, as well as both operational and denotational semantics and equational reasoning principles.
- Published
- 2024
50. Pushing Rendering Boundaries: Hard Gaussian Splatting
- Author
-
Xu, Qingshan, Cui, Jiequan, Yi, Xuanyu, Wang, Yuxuan, Zhou, Yuan, Ong, Yew-Soon, and Zhang, Hanwang
- Subjects
Computer Science - Computer Vision and Pattern Recognition - Abstract
3D Gaussian Splatting (3DGS) has demonstrated impressive Novel View Synthesis (NVS) results in a real-time rendering manner. During training, it relies heavily on the average magnitude of view-space positional gradients to grow Gaussians to reduce rendering loss. However, this average operation smooths the positional gradients from different viewpoints and rendering errors from different pixels, hindering the growth and optimization of many defective Gaussians. This leads to strong spurious artifacts in some areas. To address this problem, we propose Hard Gaussian Splatting, dubbed HGS, which considers multi-view significant positional gradients and rendering errors to grow hard Gaussians that fill the gaps of classical Gaussian Splatting on 3D scenes, thus achieving superior NVS results. In detail, we present positional gradient driven HGS, which leverages multi-view significant positional gradients to uncover hard Gaussians. Moreover, we propose rendering error guided HGS, which identifies noticeable pixel rendering errors and potentially over-large Gaussians to jointly mine hard Gaussians. By growing and optimizing these hard Gaussians, our method helps to resolve blurring and needle-like artifacts. Experiments on various datasets demonstrate that our method achieves state-of-the-art rendering quality while maintaining real-time efficiency.
- Published
- 2024
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