Author: "Onerci, M." - Searchworks@Jio Institute Digital Library Search Results

Your search keyword '"Onerci, M."' showing total 125 results

Start Over Author "Onerci, M."

125 results on '"Onerci, M."'

1. The comparison of the quality of life and intranasal edema between the patients with or without nasal packing after septoplasty

Author: Kayahan, B., Ozer, S., Suslu, A. E., Ogretmenoglu, O., and Onerci, M.
Published: 2017
Full Text: View/download PDF

2. Prospective multicentre study on barbed reposition pharyngoplasty standing alone or as a part of multilevel surgery for sleep apnoea

Author: Montevecchi, F., Meccariello, G., Firinu, E., Rashwan, M. S., Arigliani, M., De Benedetto, M., Palumbo, A., Bahgat, Y., Bahgat, A., Lugo Saldana, R., Marzetti, A., Pignataro, L., Mantovani, M., Rinaldi, V., Carrasco, M., Freire, F., Delgado, I., Salamanca, F., Bianchi, A., Onerci, M., Agostini, P., Romano, L., Benazzo, M., Baptista, P., Salzano, F., Dallan, I., Nuzzo, S., and Vicini, C.
Published: 2018
Full Text: View/download PDF

3. Positioning the principles of precision medicine in care pathways for allergic rhinitis and chronic rhinosinusitis – A EUFOREA‐ARIA‐EPOS‐AIRWAYS ICP statement

Author: Hellings, P. W., Fokkens, W. J., Bachert, C., Akdis, C. A., Bieber, T., Agache, I., Bernal‐Sprekelsen, M., Canonica, G. W., Gevaert, P., Joos, G., Lund, V., Muraro, A., Onerci, M., Zuberbier, T., Pugin, B., Seys, S. F., Bousquet, J., Aberer, W, Agache, I, Akdis, CA, Akdis, M, Alobid, I, Ankri, J, Annesi‐Maesano, I, Ansotegui, IJ, Anto, JM, Arnavielhe, S, Arshad, H, Asarnoj, A, Avolio, F, Bachert, C, Bachert, C, Baiardini, I, Barbagallo, M, Barbara, C, Baroody, F, Bateman, ED, Bedbrook, A, Beghé, B, Bel, EH, Bennoor, KS, Benson, M, Bergmann, KC, Bewick, M, Bialoszewski, AZ, Bieber, T, Bindslev‐Jensen, C, Bjermer, L, Blain, H, Blasi, F, Boner, AL, Bonini, M, Bonini, S, Bosnic‐Anticevich, S, Bosse, I, Bouchard, J, Boulet, LP, Bourret, R, Bousquet, J, Bousquet, PJ, Braido, F, Briggs, AH, Brightling, CE, Brozek, J, Bucca, C, Buhl, R, Bunu, C, Burte, E, Bush, A, Caballero‐Fonseca, F, Caimmi, DP, Calderon, MA, Camargos, PA, Camuzat, T, Canonica, GW, Cardona, V, Carlsen, KH, Carr, W, Carreiro‐Martins, P, Carriazo, AM, Casale, T, Cepeda Sarabia, AM, Cervin, A, Cesari, M, Chatzi, L, Chavannes, NH, Chiron, R, Chivato, T, Chkhartishvili, E, Chuchalin, AG, Chung, KF, Ciprandi, G, Cohen, N, Conzález Diaz, S, Cox, L, Crooks, G, Cruz, AA, Custovic, A, Dahl, R, Dahlen, SE, Darsow, U, De Carlo, G, De Manuel Keenoy, E, de Sousa, JC, De Vries, G, Dedeu, T, Deleanu, D, Demoly, P, Denburg, JA, Devillier, P, Didier, A, Dinh‐Xuan, AT, Dokic, D, Douagui, H, Douglas, R, Dray, G, Du Toit, G, Dubakiene, R, Durham, SR, Dykewicz, MS, Eklund, P, El‐Gamal, Y, Ellers, E, Emuzyte, R, Farrell, J, Fink Wagner, A, Fiocchi, A, Fletcher, M, Fokkens, WJ, Fonseca, J, Forastiere, F, Gaga, M, Gamkrelidze, A, Gemicioğlu, B, Georgalas, C, Gereda, JE, Gevaert, P, Goossens, H, Grisle, I, Guldemond, NA, Gutter, Z, Guzmán, MA, Haahtela, T, Harvey, R, Heinrich, J, Hellings, PW, Hellings, PW, Hellquist‐Dahl, B, Hopkins, C, Horak, F, Hourihane, JO, Humbert, M, Hyland, M, Iaccarino, G, Illario, M, Jares, EJ, Jeandel, C, Johnston, SL, Jonquet, O, Joos, G, Joos, G, Jung, KS, Just, J, Jutel, M, Kaidashev, I, Kalayci, O, Kalogjera, L, Kalyoncu, AF, Kardas, P, Keil, T, Keith, PK, Kerkhof, M, Kern, B, Kerstjens, HA, Khaitov, M, Khaltaev, N, Klimek, L, Kogevinas, M, Kolek, V, Koppelman, GH, Kowalski, M, Kowalski, ML, Kuitunen, M, Kull, I, Kuna, P, Kvedariene, V, Lambrecht, B, Larenas‐Linnemann, D, Lau, S, Laune, D, Le, LT, Li, J, Lieberman, P, Lipworth, B, Lodrup Carlsen, KC, Louis, R, Lund, VJ, Lupinek, C, MacNee, W, Magar, Y, Magnan, A, Mahboub, B, Maier, D, Majer, I, Malva, J, Manning, P, Marshall, GD, Masjedi, MR, Mathieu‐Dupas, E, Maurer, M, Mavale‐Manuel, S, Melén, E, Melo‐Gomes, E, Meltzer, EO, Mercier, J, Merk, H, Miculinic, N, Mihaltan, F, Milenkovic, B, Millot‐Keurinck, J, Mohammad, Y, Momas, I, Morais‐Almeida, M, Mösges, R, Mullol, J, Mullol, J, Muraro, A, Murray, R, Naclerio, R, Nadif, R, Namazova‐Baranova, L, Neffen, H, Nekam, K, Nieto, A, Niggemann, B, Nogueira‐Silva, L, Nogues, M, Nyembue, TD, OʼHehir, RE, Ohta, K, Okamoto, Y, Okubo, K, Olive‐Elias, M, Ouedraogo, S, Paggiaro, P, Pali‐Schöll, I, Palkonen, S, Panzner, P, Papadopoulos, NG, Papi, A, Park, HS, Passalacqua, G, Pawankar, R, Pedersen, S, Pereira, AM, Pfaar, O, Picard, R, Pigearias, B, Pin, I, Plavec, D, Pohl, W, Popov, TA, Portejoie, F, Postma, D, Potter, P, Poulsen, LK, Price, D, Price, D, Rabe, KF, Raciborski, F, Riechelmann, H, Robalo‐Cordeiro, C, Roberts, G, Rodenas, F, Rodriguez‐Mañas, L, Rolland, C, Roman Rodriguez, M, Romano, A, Rosado‐Pinto, J, Rosario, N, Rottem, M, Ryan, D, Samolinski, B, Sanchez‐Borges, M, Sastre‐Dominguez, J, Scadding, GK, Schlosser, R, Schmid‐Grendelmeier, P, Schunemann, HJ, Scichilone, N, Senior, B, Serrano, E, Sheikh, A, Shields, M, Simons, FER, Siroux, V, Sisul, JC, Skrindo, I, Smit, HA, Solé, D, Sooronbaev, T, Spranger, O, Stellato, C, Stelmach, R, Sterk, PJ, Strandberg, T, Sunyer, J, Thijs, C, Thomas, M, Todo‐Bom, A, Tomazic, PV, Toskala, E, Triggiani, M, Valenta, R, Valero, A, Valiulis, A, Valovirta, E, van Eerd, M, van Ganse, E, van Hage, M, van Wick, RG, Vandenplas, O, Varona, LL, Vazankari, T, Vellas, B, Ventura, MT, Vezzani, G, Viegi, G, Voegels, R, Vontetsianos, T, Wagenmann, M, Wahn, U, Walker, S, Wang, DY, Wang, Y, Werfel, T, Whalley, B, Wickman, M, Williams, DM, Williams, S, Wilson, N, Wormald, PJ, Wright, J, Yawn, BP, Yiallouros, PK, Yorgancioglu, A, Young, I, Yusuf, OM, Zaidi, A, Zar, HJ, Zernotti, ME, Zhang, L, Zhong, N, Zidarn, M, and Zuberbier, T
Published: 2017
Full Text: View/download PDF

4. European Position Paper on Rhinosinusitis and Nasal Polyps 2020

Author: Fokkens, W J, Lund, V J, Hopkins, C, Hellings, P W, Kern, R, Reitsma, S, Toppila-Salmi, S, Bernal-Sprekelsen, M, Mullol, J, Alobid, I, Terezinha Anselmo-Lima, W, Bachert, C, Baroody, F, von Buchwald, C, Cervin, A, Cohen, N, Constantinidis, J, De Gabory, L, Desrosiers, M, Diamant, Z, Douglas, R G, Gevaert, P H, Hafner, A, Harvey, R J, Joos, G F, Kalogjera, L, Knill, A, Kocks, J H, Landis, B N, Limpens, J, Lebeer, S, Lourenco, O, Meco, C, Matricardi, P M, O'Mahony, L, Philpott, C M, Ryan, D, Schlosser, R, Senior, B, Smith, T L, Teeling, T, Tomazic, P V, Wang, D, Zhang, L, Agius, A M, Ahlstrom-Emanuelsson, C, Alabri, R, Albu, S, Alhabash, S, Aleksic, A, Aloulah, M, Al-Qudah, M, Alsaleh, S, Baban, M A, Baudoin, T, Balvers, T, Battaglia, P, Bedoya, J D, Beule, A, Bofares, K M, Braverman, I, Brozek-Madry, E, Richard, B, Callejas, C, Carrie, S, Caulley, L, Chussi, D, de Corso, E, Coste, A, El Hadi, U, Elfarouk, A, Eloy, P H, Farrokhi, S, Felisati, G, Ferrari, M D, Fishchuk, R, Grayson, W, Goncalves, P M, Grdinic, B, Grgic, V, Hamizan, A W, Heinichen, J V, Husain, S, Ping, T I, Ivaska, J, Jakimovska, F, Jovancevic, L, Kakande, E, Kamel, R, Karpischenko, S, Kariyawasam, H H, Kawauchi, H, Kjeldsen, A, Klimek, L, Krzeski, A, Kopacheva Barsova, G, Kim, S W, Lal, D, Letort, J J, Lopatin, A, Mahdjoubi, A, Mesbahi, A, Netkovski, J, Nyenbue Tshipukane, D, Obando-Valverde, A, Okano, M, Onerci, M, Ong, Y K, Orlandi, R, Otori, N, Ouennoughy, K, Ozkan, M, Peric, A, Plzak, J, Prokopakis, E, Prepageran, N, Psaltis, A, Pugin, B, Raftopulos, M, Rombaux, P, Riechelmann, H, Sahtout, S, Sarafoleanu, C-C, Searyoh, K, Rhee, C-S, Shi, J, Shkoukani, M, Shukuryan, A K, Sicak, M, Smyth, D, Sindvongs, K, Soklic Kosak, T, Stjarne, P, Sutikno, B, Steinsvag, S, Tantilipikorn, P, Thanaviratananich, S, Tran, T, Urbancic, J, Valiulius, A, Vasquez de Aparicio, C, Vicheva, D, Virkkula, P M, Vicente, G, Voegels, R, Wagenmann, M M, Wardani, R S, Welge-Lussen, A, Witterick, I, Wright, E, Zabolotniy, D, Zsolt, B, Zwetsloot, C P, Fokkens, W J, Lund, V J, Hopkins, C, Hellings, P W, Kern, R, Reitsma, S, Toppila-Salmi, S, Bernal-Sprekelsen, M, Mullol, J, Alobid, I, Terezinha Anselmo-Lima, W, Bachert, C, Baroody, F, von Buchwald, C, Cervin, A, Cohen, N, Constantinidis, J, De Gabory, L, Desrosiers, M, Diamant, Z, Douglas, R G, Gevaert, P H, Hafner, A, Harvey, R J, Joos, G F, Kalogjera, L, Knill, A, Kocks, J H, Landis, B N, Limpens, J, Lebeer, S, Lourenco, O, Meco, C, Matricardi, P M, O'Mahony, L, Philpott, C M, Ryan, D, Schlosser, R, Senior, B, Smith, T L, Teeling, T, Tomazic, P V, Wang, D, Zhang, L, Agius, A M, Ahlstrom-Emanuelsson, C, Alabri, R, Albu, S, Alhabash, S, Aleksic, A, Aloulah, M, Al-Qudah, M, Alsaleh, S, Baban, M A, Baudoin, T, Balvers, T, Battaglia, P, Bedoya, J D, Beule, A, Bofares, K M, Braverman, I, Brozek-Madry, E, Richard, B, Callejas, C, Carrie, S, Caulley, L, Chussi, D, de Corso, E, Coste, A, El Hadi, U, Elfarouk, A, Eloy, P H, Farrokhi, S, Felisati, G, Ferrari, M D, Fishchuk, R, Grayson, W, Goncalves, P M, Grdinic, B, Grgic, V, Hamizan, A W, Heinichen, J V, Husain, S, Ping, T I, Ivaska, J, Jakimovska, F, Jovancevic, L, Kakande, E, Kamel, R, Karpischenko, S, Kariyawasam, H H, Kawauchi, H, Kjeldsen, A, Klimek, L, Krzeski, A, Kopacheva Barsova, G, Kim, S W, Lal, D, Letort, J J, Lopatin, A, Mahdjoubi, A, Mesbahi, A, Netkovski, J, Nyenbue Tshipukane, D, Obando-Valverde, A, Okano, M, Onerci, M, Ong, Y K, Orlandi, R, Otori, N, Ouennoughy, K, Ozkan, M, Peric, A, Plzak, J, Prokopakis, E, Prepageran, N, Psaltis, A, Pugin, B, Raftopulos, M, Rombaux, P, Riechelmann, H, Sahtout, S, Sarafoleanu, C-C, Searyoh, K, Rhee, C-S, Shi, J, Shkoukani, M, Shukuryan, A K, Sicak, M, Smyth, D, Sindvongs, K, Soklic Kosak, T, Stjarne, P, Sutikno, B, Steinsvag, S, Tantilipikorn, P, Thanaviratananich, S, Tran, T, Urbancic, J, Valiulius, A, Vasquez de Aparicio, C, Vicheva, D, Virkkula, P M, Vicente, G, Voegels, R, Wagenmann, M M, Wardani, R S, Welge-Lussen, A, Witterick, I, Wright, E, Zabolotniy, D, Zsolt, B, and Zwetsloot, C P
Abstract: The European Position Paper on Rhinosinusitis and Nasal Polyps 2020 is the update of similar evidence based position papers published in 2005 and 2007 and 2012. The core objective of the EPOS2020 guideline is to provide revised, up-to-date and clear evidence-based recommendations and integrated care pathways in ARS and CRS. EPOS2020 provides an update on the literature published and studies undertaken in the eight years since the EPOS2012 position paper was published and addresses areas not extensively covered in EPOS2012 such as paediatric CRS and sinus surgery. EPOS2020 also involves new stakeholders, including pharmacists and patients, and addresses new target users who have become more involved in the management and treatment of rhinosinusitis since the publication of the last EPOS document, including pharmacists, nurses, specialised care givers and indeed patients themselves, who employ increasing self-management of their condition using over the counter treatments. The document provides suggestions for future research in this area and offers updated guidance for definitions and outcome measurements in research in different settings. EPOS2020 contains chapters on definitions and classification where we have defined a large number of terms and indicated preferred terms. A new classification of CRS into primary and secondary CRS and further division into localized and diffuse disease, based on anatomic distribution is proposed. There are extensive chapters on epidemiology and predisposing factors, inflammatory mechanisms, (differential) diagnosis of facial pain, allergic rhinitis, genetics, cystic fibrosis, aspirin exacerbated respiratory disease, immunodeficiencies, allergic fungal rhinosinusitis and the relationship between upper and lower airways. The chapters on paediatric acute and chronic rhinosinusitis are totally rewritten. All available evidence for the management of acute rhinosinusitis and chronic rhinosinusitis with or without nasal polyps in adult
Published: 2020

5. Aspirin 300 mg/day is effective for treating aspirin-exacerbated respiratory disease

Author: Comert, S., Celebioglu, E., Yucel, T., Erdogan, T., Karakaya, G., Onerci, M., and Kalyoncu, A. F.
Published: 2013
Full Text: View/download PDF

6. European Position Paper on Rhinosinusitis and Nasal Polyps 2020

Author: Fokkens, W.J., primary, Lund, V.J., additional, Hopkins, C., additional, Hellings, P.W., additional, Kern, R., additional, Reitsma, S., additional, Toppila-Salmi, S., additional, Bernal-Sprekelsen, M., additional, Mullol, J., additional, Alobid, I., additional, Terezinha Anselmo-Lima, W., additional, Bachert, C., additional, Baroody, F., additional, von Buchwald, C., additional, Cervin, A., additional, Cohen, N., additional, Constantinidis, J., additional, De Gabory, L., additional, Desrosiers, M., additional, Diamant, Z., additional, Douglas, R.G., additional, Gevaert, P.H., additional, Hafner, A., additional, Harvey, R.J., additional, Joos, G.F., additional, Kalogjera, L., additional, Knill, A., additional, Kocks, J.H., additional, Landis, B.N., additional, Limpens, J., additional, Lebeer, S., additional, Lourenco, O., additional, Matricardi, P.M., additional, Meco, C., additional, O Mahony, L., additional, Philpott, C.M., additional, Ryan, D., additional, Schlosser, R., additional, Senior, B., additional, Smith, T.L., additional, Teeling, T., additional, Tomazic, P.V., additional, Wang, D.Y., additional, Wang, D., additional, Zhang, L., additional, Agius, A.M., additional, Ahlstrom-Emanuelsson, C., additional, Alabri, R., additional, Albu, S., additional, Alhabash, S., additional, Aleksic, A., additional, Aloulah, M., additional, Al-Qudah, M., additional, Alsaleh, S., additional, Baban, M.A., additional, Baudoin, T., additional, Balvers, T., additional, Battaglia, P., additional, Bedoya, J.D., additional, Beule, A., additional, Bofares, K.M., additional, Braverman, I., additional, Brozek-Madry, E., additional, Richard, B., additional, Callejas, C., additional, Carrie, S., additional, Caulley, L., additional, Chussi, D., additional, de Corso, E., additional, Coste, A., additional, Devyani, L., additional, El Hadi, U., additional, Elfarouk, A., additional, Eloy, P.H., additional, Farrokhi, S., additional, Felisati, G., additional, Ferrari, M.D., additional, Fishchuk, R., additional, Grayson, J.W., additional, Goncalves, P.M., additional, Grdinic, B., additional, Grgic, V., additional, Hamizan, A.W., additional, Heinichen, J.V., additional, Husain, S., additional, Ping, T.I., additional, Ivaska, J., additional, Jakimovska, F., additional, Jovancevic, L., additional, Kakande, E., additional, Kamel, R., additional, Karpischenko, S., additional, Kariyawasam, H.H., additional, Kjeldsen, A., additional, Klimek, L., additional, Kim, S.W., additional, Letort, J.J., additional, Lopatin, A., additional, Mahdjoubi, A., additional, Netkovski, J., additional, Tshipukane, D.N., additional, Obando-Valverde, A., additional, Okano, M., additional, Onerci, M., additional, Ong, Y.K., additional, Orlandi, R., additional, Ouennoughy, K., additional, Ozkan, M., additional, Peric, A., additional, Plzak, J., additional, Prokopakis, E., additional, Prepageran, N., additional, Psaltis, A., additional, Pugin, B., additional, Raftopulos, M., additional, Rombaux, P., additional, Sahtout, S., additional, Sarafoleanu, C.-C., additional, Searyoh, K., additional, Rhee, C.-S., additional, Shi, J., additional, Shkoukani, M., additional, Shukuryan, A.K., additional, Sicak, M., additional, Smyth, D., additional, Snidvongs, K., additional, Kosak, T.S., additional, Stjarne, P., additional, Sutikno, B., additional, Steinsvag, S., additional, Tantilipikorn, P., additional, Thanaviratananich, S., additional, Tran, T., additional, Urbancic, J., additional, Valiulis, A., additional, de Aparicio, C.V., additional, Vicheva, D., additional, Virkkula, P.M., additional, Vicente, G., additional, Voegels, R., additional, Wagenmann, M.M., additional, Wardani, R.S., additional, Welge-Lussen, A., additional, Witterick, I., additional, Wright, E., additional, Zabolotniy, D., additional, Zsolt, B., additional, and Zwetsloot, C.P., additional
Published: 2020
Full Text: View/download PDF

7. Positioning the principles of precision medicine in care pathways for allergic rhinitis and chronic rhinosinusitis â A EUFOREA-ARIA-EPOS-AIRWAYS ICP statement

Author: Hellings, P. W., Fokkens, W. J., Bachert, C., Akdis, C. A., Bieber, T., Agache, I., Bernal-Sprekelsen, M., Canonica, G. W., Gevaert, P., Joos, G., Lund, V. J., Muraro, A., Onerci, M., Zuberbier, T., Pugin, B., Seys, S. F., Bousquet, Jean, ARIA and EPOS working groups, Akdis, M., Alobid, I., Ankri, J., Annesi-Maesano, I., Ansotegui, I. J., Anto, Josep M., Arnavielhe, S., Arshad, S. H., Asarnoj, A., Avolio, F., Baiardini, I., Barbagallo, Carlo M., Barbara, Cristina, Baroody, F., Bateman, E. D., Bedbrook, Anna, Beghé, B., Bel, E. H., Bennoor, K. S., Benson, M., Bergmann, K. C., Bewick, M., Białoszewski, A. Z., Bindslev-Jensen, C., Bjermer, L., Blain, Hubert, Blasi, F., Boner, A. L., Bonini, M., Bonini, S., Bosnic-Anticevitch, S., Bosse, I., Bouchard, J., Boulet, L. P., Bourret, Rodolphe, Braido, F., Briggs, A. H., Brightling, C. E., Brozek, J. L., Bucca, C., Buhl, R., Bunu, C., Burte, E., Bush, A., Caballero-Fonseca, F., Caimmi, D. P., Calderon, M. A., Camargos, P. A. M., Camuzat, Thierry, Cardona, V., Carlsen, K. H., Carr, W., Carreiro-Martins, P., Carriazo, A. M., Casale, T. B., A.M, Cepeda Sarabia, Cervin, A., Cesari, M., Chatzi, L., Chavannes, Niels H., Chiron, R., Pérez, T. Chivato, Chkhartishvili, E., Chuchalin, Alexander G., Chung, K. F., Ciprandi, G., Cohen, N., Diaz, S. Conzález, Cox, L., Crooks, George, Cruz, A. A., Custovic, Adnan, Dahl, R., Dahlen, S. E., Darsow, U., Carlo, G. De, Keenoy, E. De Manuel, Sousa, J. Correia de, Vries, Elisabeth G. E. de, Dedeu, Antoni, Deleanu, D., Demoly, Pascal, Denburg, J. A., Devillier, P., Didier, A., Dinh-Xuan, A. T., Dokic, D., Douagui, H. B., Douglas, R., Dray, G., Toit, G. Du, Dubakiene, R., Durham, S. R., Dykewicz, M. S., Eklund, P., El-Gamal, Y., Ellers, E., Emuzyte, R., Farrell, J., Fink-Wagner, A., Fiocchi, A., Fletcher, M., Fonseca, J. A., Forastiere, F., Gaga, M., Gamkrelidze, A., Gemicioǧlu, B., Georgalas, C., Gereda, J. E., Goossens, H., Grisle, I., Guldemond, N. A., Gutter, Z., Guzmán, M. A., Haahtela, T., Harvey, R., Heinrich, J., Hellquist-Dahl, B., Hopkins, C., Horak, F., Hourihane, J. O. B., Humbert, M., Hyland, M. E., Iaccarino, G., Illario, M., Jares, E. J., Jeandel, Claude, Johnston, S. L., Jonquet, Olivier, Jung, K. S., Just, J., Jutel, M., Kaidashev, I. P., Kalayci, O., Kalogjera, L., Kalyoncu, A. F., Kardas, P., Keil, T., Keith, P. K., Kerkhof, M., Kern, B., Kerstjens, H. A. M., Khaitov, M. R., Khaltaev, N., Klimek, L., Kogevinas, M., Kolek, V., Koppelman, G. H., Kowalski, M. L., Kuitunen, M., Kull, I., Kuna, P., Kvedariene, V., Lambrecht, B., Larenas-Linnemann, D., Lau, S., Laune, D., Le, Tuyen D., Li, J., Lieberman, P., Lipworth, B. J., Carlsen, K. C. Lodrup, Louis, R., Lupinek, C., MacNee, W., Magard, Y., Magnan, A., Mahboub, B., Maier, D., Majer, I., Malva, J., Manning, P. J., Marshall, G. D., Masjedi, M. R., Mathieu-Dupas, E., Maurer, M., Mavale-Manuel, S., Melén, E., Gomes, Elisabete Melo, Meltzer, E. O., Mercier, Jacques, Merk, H., Miculinic, N., Mihaltan, F., Milenkovic, B., Millot-Keurinck, J., Mohammad, Y., Momas, I., Almeida, M. Morais, Mosges, R., Mullol, J., Murray, R., Naclerio, R. N., Nadif, R., Namazova-Baranova, L., Neffen, H., Nekam, K., Nieto, A., Niggemann, B., Nogueira-Silva, L., Nogues, M., Nyembue, T. D., O'Hehir, R. E., Ohta, K., Okamoto, Y., Okubo, K., Olive-Elias, M., Ouedraogo, S., Paggiaro, P. L., Pali-Schöll, I., Palkonen, S., Panzner, P., Papadopoulos, N. G., Papi, A., Park, H. S., Passalacqua, G., Pawankar, R., Pedersen, S., Pereira, A. M., Pfaar, O., Picard, R., Pigearias, B., Pin, I., Plavec, D., Pohl, W., Popov, T. A., Portejoie, F., Postma, D. S., Potter, P., Poulsen, L. K., Price, D., Rabe, K. F., Raciborski, F., Riechelmann, H., Robalo-Cordeiro, C., Roberts, G., Rodenas, F., Rodriguez-Mañas, L., Rolland, C., Rodriguez, M. Roman, Romano, A., Rosado-Pinto, J., Rosario, N. A., Rottem, M., Ryan, D., Samolinski, B., Sanchez-Borges, M., Sastre-Dominguez, J., Scadding, G. K., Schlosser, R., Schmid-Grendelmeier, P., Schunemann, H. J., Scichilone, N., Senior, B., Serrano, E., Sheikh, A., Shields, K. M., Simons, F. E. R., Siroux, V., Sisul, J. C., Skrindo, I., Smit, H. A., Sole, D., Sooronbaev, T., Spranger, O., Stellato, C., Stelmach, R., Sterk, P. J., Strandberg, T., Sunyer, Jordi, Thijs, C., Thomas, M., Todo-Bom, A., Tomazic, P. V., Toskala, E., Triggiani, M., Valenta, R., Valero, A. L., Valiulis, A., Valovirta, E., Eerd, M. van, Ganse, E. van, Hage, M. van, Wick, R. G. van, Vandenplas, O., Varona, L. L., Vazankari, T., Vellas, B., Ventura, M. T., Vezzani, G., Viegi, Giovanni, Voegels, R., Vontetsianos, T., Wagenmann, M., Wahn, U., Walker, S., Wang, D. Y., Wang, Ya Xing, Werfel, T., Whalley, B., Wickman, M., Williams, D. M., Williams, S., Wilson, N., Wormald, P. J., Wright, J., Yawn, B. P., Yiallouros, Panayiotis K., Yorgancioglu, A., Young, I., Yusuf, O. M., Zaidi, A., Zar, H. J., Zernotti, M. E., Zhang, L., Zhong, N., Zidarn, M., Adult Psychiatry, Ear, Nose and Throat, AII - Inflammatory diseases, AII - Amsterdam institute for Infection and Immunity, Pulmonology, Other departments, Hellings, P. W., Fokkens, W. J., Bachert, C., Akdis, C. A., Bieber, T., Agache, I., Bernal-Sprekelsen, M., Canonica, G. W., Gevaert, P., Joos, G., Lund, V., Muraro, A., Onerci, M., Zuberbier, T., Pugin, B., Seys, S. F., Bousquet, J., Aberer, W., Akdis, M., Alobid, I., Ankri, J., Annesi-Maesano, I., Ansotegui, I. J., Anto, J. M., Arnavielhe, S., Arshad, H., Asarnoj, A., Avolio, F., Baiardini, I., Barbagallo, M., Barbara, C., Baroody, F., Bateman, E. D., Bedbrook, A., Beghe, B., Bel, E. H., Bennoor, K. S., Benson, M., Bergmann, K. C., Bewick, M., Bialoszewski, A. Z., Bindslev-Jensen, C., Bjermer, L., Blain, H., Blasi, F., Boner, A. L., Bonini, M., Bonini, S., Bosnic-Anticevich, S., Bosse, I., Bouchard, J., Boulet, L. P., Bourret, R., Bousquet, P. J., Braido, F., Briggs, A. H., Brightling, C. E., Brozek, J., Bucca, C., Buhl, R., Bunu, C., Burte, E., Bush, A., Caballero-Fonseca, F., Caimmi, D. P., Calderon, M. A., Camargos, P. A., Camuzat, T., Cardona, V., Carlsen, K. H., Carr, W., Carreiro-Martins, P., Carriazo, A. M., Casale, T., Cepeda Sarabia, A. M., Cervin, A., Cesari, M., Chatzi, L., Chavannes, N. H., Chiron, R., Chivato, T., Chkhartishvili, E., Chuchalin, A. G., Chung, K. F., Ciprandi, G., Cohen, N., Conzalez Diaz, S., Cox, L., Crooks, G., Cruz, A. A., Custovic, A., Dahl, R., Dahlen, S. E., Darsow, U., De Carlo, G., De Manuel Keenoy, E., de Sousa, J. C., De Vries, G., Dedeu, T., Deleanu, D., Demoly, P., Denburg, J. A., Devillier, P., Didier, A., Dinh-Xuan, A. T., Dokic, D., Douagui, H., Douglas, R., Dray, G., Du Toit, G., Dubakiene, R., Durham, S. R., Dykewicz, M. S., Eklund, P., El-Gamal, Y., Ellers, E., Emuzyte, R., Farrell, J., Fink Wagner, A., Fiocchi, A., Fletcher, M., Fonseca, J., Forastiere, F., Gaga, M., Gamkrelidze, A., Gemicioglu, B., Georgalas, C., Gereda, J. E., Goossens, H., Grisle, I., Guldemond, N. A., Gutter, Z., Guzman, M. A., Haahtela, T., Harvey, R., Heinrich, J., Hellquist-Dahl, B., Hopkins, C., Horak, F., Hourihane, J. O., Humbert, M., Hyland, M., Iaccarino, G., Illario, M., Jares, E. J., Jeandel, C., Johnston, S. L., Jonquet, O., Jung, K. S., Just, J., Jutel, M., Kaidashev, I. P., Kalayci, O., Kalogjera, L., Kalyoncu, A. F., Kardas, P., Keil, T., Keith, P. K., Kerkhof, M., Kern, B., Kerstjens, H. A., Khaitov, M., Khaltaev, N., Klimek, L., Kogevinas, M., Kolek, V., Koppelman, G. H., Kowalski, M., Kowalski, M. L., Kuitunen, M., Kull, I., Kuna, P., Kvedariene, V., Lambrecht, B., Larenas-Linnemann, D., Lau, S., Laune, D., Le, L. T., Li, J., Lieberman, P., Lipworth, B., Lodrup Carlsen, K. C., Louis, R., Lund, V. J., Lupinek, C., Macnee, W., Magar, Y., Magnan, A., Mahboub, B., Maier, D., Majer, I., Malva, J., Manning, P., Marshall, G. D., Masjedi, M. R., Mathieu-Dupas, E., Maurer, M., Mavale-Manuel, S., Melen, E., Melo-Gomes, E., Meltzer, E. O., Mercier, J., Merk, H., Miculinic, N., Mihaltan, F., Milenkovic, B., Millot-Keurinck, J., Mohammad, Y., Momas, I., Morais-Almeida, M., Mosges, R., Mullol, J., Murray, R., Naclerio, R., Nadif, R., Namazova-Baranova, L., Neffen, H., Nekam, K., Nieto, A., Nogues, M., Nyembue, T. D., O'Hehir, R. E., Ohta, K., Okamoto, Y., Okubo, K., Olive-Elias, M., Ouedraogo, S., Paggiaro, P., Pali-Scholl, I., Palkonen, S., Panzner, P., Papadopoulos, N. G., Papi, A., Park, H. S., Passalacqua, G., Niggemann, B., Nogueira-Silva, L., Pereira, A. M., Pfaar, O., Picard, R., Pigearias, B., Pin, I., Plavec, D., Pohl, W., Popov, T. A., Portejoie, F., Postma, D., Potter, P., Poulsen, L. K., Price, D., Rabe, K. F., Raciborski, F., Riechelmann, H., Robalo-Cordeiro, C., Roberts, G., Rodenas, F., Rodriguez-Manas, L., Rolland, C., Roman Rodriguez, M., Romano, A., Rosado-Pinto, J., Rosario, N., Rottem, M., Ryan, D., Samolinski, B., Sanchez-Borges, M., Sastre-Dominguez, J., Scadding, G. K., Schlosser, R., Schmid-Grendelmeier, P., Schunemann, H. J., Scichilone, N., Senior, B., Serrano, E., Sheikh, A., Shields, M., Simons, F. E. R., Siroux, V., Sisul, J. C., Skrindo, I., Smit, H. A., Sole, D., Sooronbaev, T., Spranger, O., Stellato, C., Stelmach, R., Sterk, P. J., Strandberg, T., Sunyer, J., Thijs, C., Thomas, M., Todo-Bom, A., Tomazic, P. V., Toskala, E., Triggiani, M., Valenta, R., Valero, A., Valiulis, A., Valovirta, E., van Eerd, M., van Ganse, E., van Hage, M., van Wick, R. G., Vandenplas, O., Varona, L. L., Vazankari, T., Vellas, B., Ventura, M. T., Vezzani, G., Viegi, G., Voegels, R., Vontetsianos, T., Wagenmann, M., Wahn, U., Walker, S., Wang, D. Y., Wang, Y., Werfel, T., Whalley, B., Wickman, M., Williams, D. M., Williams, S., Wilson, N., Wormald, P. J., Wright, J., Yawn, B. P., Yiallouros, P. K., Yorgancioglu, A., Young, I., Yusuf, O. M., Zaidi, A., Zar, H. J., Zernotti, M. E., Zhang, L., Zhong, N., Zidarn, M., Asthma UK, Department of Dermatology, Allergology and Venereology, Clinicum, HUS Inflammation Center, RS: CAPHRI - R5 - Optimising Patient Care, Epidemiologie, Yiallouros, Panayiotis K. [0000-0002-8339-9285], Custovic, Adnan [0000-0001-5218-7071], Hellings, P.W., Fokkens, W.J., Akdis, C.A., Canonica, G.W., Seys, S.F., Ansotegui, I.J., Anto, J.M., Bateman, E.D., Beghé, B., Bel, E.H., Bennoor, K.S., Bergmann, K.C., Bialoszewski, A.Z., Boner, A.L., Boulet, L.P., Bousquet, P.J., Briggs, A.H., Brightling, C.E., Caimmi, D.P., Calderon, M.A., Camargos, P.A., Carlsen, K.H., Carriazo, A.M., Cepeda Sarabia, A.M., Chavannes, N.H., Chuchalin, A.G., Chung, K.F., Conzález Diaz, S., Cruz, A.A., Dahlen, S.E., de Sousa, J.C., Denburg, J.A., Dinh-Xuan, A.T., Durham, S.R., Dykewicz, M.S., Gemicioğlu, B., Gereda, J.E., Guldemond, N.A., Guzmán, M.A., Hourihane, J.O., Jares, E.J., Johnston, S.L., Jung, K.S., Kaidashev, I., Kalyoncu, A.F., Keith, P.K., Kerstjens, H.A., Koppelman, G.H., Kowalski, M.L., Le, L.T., Lodrup Carlsen, K.C., Lund, V.J., MacNee, W., Marshall, G.D., Masjedi, M.R., Melén, E., Meltzer, E.O., Mösges, R., Nyembue, T.D., O'Hehir, R.E., Pali-Schöll, I., Papadopoulos, N.G., Park, H.S., Pawankar, R., Pedersen, S., Pereira, A.M., Popov, T.A., Poulsen, L.K., Rabe, K.F., Rodriguez-Mañas, L., Scadding, G.K., Schunemann, H.J., Simons, F.E.R., Sisul, J.C., Smit, H.A., Solé, D., Sterk, P.J., Tomazic, P.V., van Wick, R.G., Varona, L.L., Ventura, M.T., Wang, D.Y., Williams, D.M., Wormald, P.J., Yawn, B.P., Yiallouros, P.K., Yusuf, O.M., Zar, H.J., and Zernotti, M.E.
Subjects: allergic rhinitis, integrated care pathway, precision medicine, rhinosinusitis, Allergy, Rhinosinusitis, Disease, Allergic rhinitis, 0302 clinical medicine, QUALITY-OF-LIFE, Medicine, Immunology and Allergy, 030223 otorhinolaryngology, Sinusitis, NASAL POLYPOSIS, Rhinitis, Precision medicine, 3. Good health, Algorithm, REAL-LIFE, IMPACT OUTCOMES, ARIA and EPOS working groups, 1107 Immunology, DISEASES, GA(2)LEN, Disease Progression, allergic rhiniti, Life Sciences & Biomedicine, ENDOSCOPIC SINUS SURGERY, Algorithms, Human, Integrated care pathway, Adult, Chronic Disease, Humans, Precision Medicine, Rhinitis, Allergic, Young Adult, Immunology, medicine.medical_specialty, rhinosinusiti, PHENOTYPES, VALIDATION, 03 medical and health sciences, Therapeutic approach, Allergic, Patient satisfaction, Quality of life (healthcare), Patient participation, IMMUNOTHERAPY, Intensive care medicine, Asthma, Science & Technology, business.industry, medicine.disease, Sinusiti, SEVERITY, 030228 respiratory system, 3121 General medicine, internal medicine and other clinical medicine, Physical therapy, ASTHMA, business
Abstract: Precision medicine (PM) is increasingly recognized as the way forward for optimizing patient care. Introduced in the field of oncology, it is now considered of major interest in other medical domains like allergy and chronic airway diseases, which face an urgent need to improve the level of disease control, enhance patient satisfaction and increase effectiveness of preventive interventions. The combination of personalized care, prediction of treatment success, prevention of disease and patient participation in the elaboration of the treatment plan is expected to substantially improve the therapeutic approach for individuals suffering from chronic disabling conditions. Given the emerging data on the impact of patient stratification on treatment outcomes, European and American regulatory bodies support the principles of PM and its potential advantage over current treatment strategies. The aim of the current document was to propose a consensus on the position and gradual implementation of the principles of PM within existing adult treatment algorithms for allergic rhinitis (AR) and chronic rhinosinusitis (CRS). At the time of diagnosis, prediction of success of the initiated treatment and patient participation in the decision of the treatment plan can be implemented. The second-level approach ideally involves strategies to prevent progression of disease, in addition to prediction of success of therapy, and patient participation in the long-term therapeutic strategy. Endotype-driven treatment is part of a personalized approach and should be positioned at the tertiary level of care, given the efforts needed for its implementation and the high cost of molecular diagnosis and biological treatment. © 2017 EAACI and John Wiley and Sons A/S. Published by John Wiley and Sons Ltd. 72 9 1297 1305
Published: 2017

8. Positioning the Principles of Precision Medicine in Care Pathways for Allergic Rhinitis and Chronic Rhinosinusitis - an EUFOREA-ARIA-EPOS-AIRWAYS ICP statement

Author: Hellings, P W, Fokkens, W J, Bachert, C, Akdis, C A, Bieber, T, Agache, I, Bernal-Sprekelsen, M, Canonica, G W, Gevaert, P, Joos, G, Lund, V, Muraro, A, Onerci, M, Zuberbier, T, Pugin, B, Seys, S F, Bousquet, J, ARIA, EPOS, University of Zurich, and Hellings, P W
Subjects: 2403 Immunology, allergic rhinitis, 10183 Swiss Institute of Allergy and Asthma Research, precision medicine, Immunology, 2723 Immunology and Allergy, 10177 Dermatology Clinic, Immunology and Allergy, 610 Medicine & health, integrated care pathway, rhinosinusitis
Abstract: Precision medicine (PM) is increasingly recognized as the way forward for optimizing patient care. Introduced in the field of oncology, it is now considered of major interest in other medical domains like allergy and chronic airway diseases, which face an urgent need to improve the level of disease control, enhance patient satisfaction and increase effectiveness of preventive interventions. The combination of personalized care, prediction of treatment success, prevention of disease and patient participation in the elaboration of the treatment plan is expected to substantially improve the therapeutic approach for individuals suffering from chronic disabling conditions. Given the emerging data on the impact of patient stratification on treatment outcomes, European and American regulatory bodies support the principles of PM and its potential advantage over current treatment strategies. The aim of the current document was to propose a consensus on the position and gradual implementation of the principles of PM within existing adult treatment algorithms for allergic rhinitis (AR) and chronic rhinosinusitis (CRS). At the time of diagnosis, prediction of success of the initiated treatment and patient participation in the decision of the treatment plan can be implemented. The second-level approach ideally involves strategies to prevent progression of disease, in addition to prediction of success of therapy, and patient participation in the long-term therapeutic strategy. Endotype-driven treatment is part of a personalized approach and should be positioned at the tertiary level of care, given the efforts needed for its implementation and the high cost of molecular diagnosis and biological treatment.
Published: 2017

9. mySinusitisCoach: patient empowerment in chronic rhinosinusitis using mobile technology

Author: Seys, S.F., primary, Bousquet, J., additional, Bachert, C., additional, Fokkens, W.J., additional, Agache, I., additional, Bernal-Sprekelsen, M., additional, Callebaut, I., additional, Cardel, L.O., additional, Carrie, S., additional, Castelnuovo, P., additional, Cathcart, R., additional, Constantinidis, J., additional, Cools, L., additional, Cornet, M., additional, Clement, G., additional, de Sousa, J.C., additional, Cox, T., additional, Doulaptsi, M., additional, Gevaert, P., additional, Hopkins, C., additional, Hox, V., additional, Hummel, T., additional, Hosemann, W., additional, Jacobs, R., additional, Jorissen, M., additional, Landis, B.N., additional, Leunig, A., additional, Lund, V.J., additional, Mullol, J., additional, Onerci, M., additional, Palkonen, S., additional, Proano, I., additional, Prokopakis, E., additional, Ryan, D., additional, Riechelmann, H., additional, Saevels, J., additional, Segboer, C., additional, Speleman, K., additional, Steinsvik, E.A., additional, Surda, P., additional, Tomazic, P.V., additional, Vanderveken, O., additional, Van Gerven, L., additional, Van Zele, T., additional, Verhaeghe, B., additional, Vierstraete, K., additional, Vlaminck, S., additional, Wilkinson, J., additional, Williams, S., additional, Pugin, B., additional, and Hellings, P.W., additional
Published: 2018
Full Text: View/download PDF

10. Positioning the principles of precision medicine in care pathways for allergic rhinitis and chronic rhinosinusitis : A EUFOREA-ARIA-EPOS-AIRWAYS ICP statement

Author: Hellings, Peter W, Fokkens, Wytske J, Bachert, C., Akdis, Cezmi A, Bieber, T., Agache, I., Bernal-Sprekelsen, M, Canonica, G Walter, Gevaert, P., Joos, G., Lund, V.J., Muraro, A., Onerci, M, Zuberbier, T., Pugin, B, Seys, S F, Bousquet, J., ARIA and EPOS working groups, Smit, HA, Hellings, Peter W, Fokkens, Wytske J, Bachert, C., Akdis, Cezmi A, Bieber, T., Agache, I., Bernal-Sprekelsen, M, Canonica, G Walter, Gevaert, P., Joos, G., Lund, V.J., Muraro, A., Onerci, M, Zuberbier, T., Pugin, B, Seys, S F, Bousquet, J., ARIA and EPOS working groups, and Smit, HA
Published: 2017

11. Positioning the principles of precision medicine in care pathways for allergic rhinitis and chronic rhinosinusitis: A EUFOREA-ARIA-EPOS-AIRWAYS ICP statement

Author: Public Health Epidemiologie, Circulatory Health, Child Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, JC onderzoeksprogramma Infectieziekten, Hellings, Peter W, Fokkens, Wytske J, Bachert, C., Akdis, Cezmi A, Bieber, T., Agache, I., Bernal-Sprekelsen, M, Canonica, G Walter, Gevaert, P., Joos, G., Lund, V.J., Muraro, A., Onerci, M, Zuberbier, T., Pugin, B, Seys, S F, Bousquet, J., ARIA and EPOS working groups, Smit, HA, Public Health Epidemiologie, Circulatory Health, Child Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, JC onderzoeksprogramma Infectieziekten, Hellings, Peter W, Fokkens, Wytske J, Bachert, C., Akdis, Cezmi A, Bieber, T., Agache, I., Bernal-Sprekelsen, M, Canonica, G Walter, Gevaert, P., Joos, G., Lund, V.J., Muraro, A., Onerci, M, Zuberbier, T., Pugin, B, Seys, S F, Bousquet, J., ARIA and EPOS working groups, and Smit, HA
Published: 2017

12. Injuries due to foreign body aspirations in Georgia: A prevention perspective

Author: Gvetadze, P. Chkhaidze, I. Baldas, S. Comoretto, R. Gregori, D. Berchialla, P. Rodriguez, H. Zaupa, P. Spitzer, P. Demetriades, C. Slapák, I. Sokolova, L. Petridou, E. Antonio Caldeira Pais Clemente, M. Jakubíková, J. Van As, S. De Koning, T. Passali, D. Cuestas, G. Bouchikhi, N. Chinsky, A. Ro, H. Tortosa, S. Alassia, O. Abete, F. Sica, G. Di Blasio, A. Rodríguez, V. Taire, D. Paoli, B. Rene Marquez, C. Razetti, J. Adolfo Mariotti, C. Héctor Ariel, A. Zanetta, A. Dario, F. Milena Pabón, S. Quijano, A. Elena Nieto, M. Villca, N. Brkic, F. Reis, M. Manrique, D. Nkodo, Y. Ludemann, J. Cheng peng, J. Barón Puentes, O.U. Mladina, R. Gomez De La Rosa, E. Kalakouta, O. eas Melis, A. Zeitouni, F. Máchalová, M. Slapak, J. Pecková, P. Caye-Thomasen, P. Silva Chacon, F. Parker, J. Elsheikh, E. Ragab, A. Pitkäranta, A. Contencin Necker, P. Derelle, J. Duwelz, M. Francois, M. Pezzettigotta, S. Righini, C. Buzarov, J. Bernhard, R. Jahnke, V. Onder, G. Zieriacks, P. Siegfried, K. Koitschev, A. Kalampoki, V. Simasko, N. Skoulakis, C. Gulati, A. Camaioni, A. Cutrone, C. Gaudini, E. Grasso, D. Mansi, N. Messi, G. Orlando, C. Preziosi, S. Sorrentini, I. Trozzi, M. o Vigo, A. Villari, G. Cesare Passali, G. Maria Passali, F. Piantanida, R. Giordano, C. Mercuri, L. Cecconi, A. Giovari, M. Nishida, Y. Ussatayeva, G. Antonio De Hoyos Parra, R. Gonzalez, J.L. Eleuterio Gonzá lez, J. Emmanuel Ologe, F. Nasrullah, M. Melendez, A. Milanes, R. Chmielik, M. Belchior, T. Dan Cobzeanu, M. Cristian Gheorghe, D. Iorgulescu, A. Caius-Codrut Toader, M. Barkociová, J. Havelkova, B. Janka Koman, A. Zargi, M. Pumarola, F. Rubio, L. Perniás Peco, K. Stierna, P. Hsu, W. Arj-Ong, S. Chomchai, C. Chotigavanich, C. Hoep, L. Rinkel, R. Berraies, A. Aydin Baskent, E. Sarper Erikci, V. Onerci, M. Graham, J. Khwaja, S. Raine, C. Haloob, N. Doassans Goḿez Haedo, I. Mehta, D. Casselbrant, M. Susy Safe Working Group
Abstract: Background: Suffocation due to foreign bodies (FB) is a leading cause of death in children aged 0-3. No data from the former U.S.S.R. are available in the international scientific literature. Methods: Consecutive patients admitted at the Iashvili Central Children Hospital in Tbilisi, Georgia from 1989 to 2011 were analyzed. Injuries in the upper airways due to foreign bodies' inhalation were collected and compared with the Susy Safe Registry and the pooled estimates of the meta-analysis. Results: 2896 cases were collected. Distribution of injuries in children younger than 3 years was significantly higher than in the Susy Safe Registry and in the "High-Income" countries in the meta-analysis. Percentage of injuries due to organic objects (86%) was significantly higher than in published data. Conclusions: Since Georgia is not showing any substantial difference, both in epidemiology and treatment of foreign bodies injuries, as compared to the other case series, translation of public health initiatives from other most advanced prevention experiences is possible and it is likely to be effective. Level of evidence: Level V, Epidemiological case series. © 2015 Elsevier Ireland Ltd.
Published: 2016

13. Prospective multicentre study on barbed reposition pharyngoplasty standing alone or as a part of multilevel surgery for sleep apnoea

Author: Montevecchi, F., primary, Meccariello, G., additional, Firinu, E., additional, Rashwan, M. S., additional, Arigliani, M., additional, De Benedetto, M., additional, Palumbo, A., additional, Bahgat, Y., additional, Bahgat, A., additional, Lugo Saldana, R., additional, Marzetti, A., additional, Pignataro, L., additional, Mantovani, M., additional, Rinaldi, V., additional, Carrasco, M., additional, Freire, F., additional, Delgado, I., additional, Salamanca, F., additional, Bianchi, A., additional, Onerci, M., additional, Agostini, P., additional, Romano, L., additional, Benazzo, M., additional, Baptista, P., additional, Salzano, F., additional, Dallan, I., additional, Nuzzo, S., additional, and Vicini, C., additional
Published: 2017
Full Text: View/download PDF

14. Rhinology Future Debates, an EUFOREA Report

Author: Fokkens, W.J., primary, Bachert, C., additional, Bernal-Sprekelsen, M., additional, Bousquet, J., additional, Djandji, M., additional, Dorenbaum, A., additional, Hakimi-Mehr, D., additional, Hendry, S., additional, Hopkins, C., additional, Leunig, A., additional, Mannent, L., additional, Mucha, D., additional, Onerci, M., additional, Pugin, B., additional, Toppila-Salmi, S., additional, Rowe, P., additional, Seys, S.F., additional, Stimson, S., additional, Strzemosz, A., additional, and Hellings, P.W., additional
Published: 2017
Full Text: View/download PDF

15. Symptoms associated with button batteries injuries in children: An epidemiological review

Author: Buttazzoni, E. Gregori, D. Paoli, B. Soriani, N. Baldas, S. Rodriguez, H. Lorenzoni, G. Marquez, C.R. Cuestas, G. Sica, G. Berchialla, P. Zaupa, P. Spitzer, P. Demetriades, C. Ŝlapák, I. Sokolova, L. Petridou, E. Antonio, M. Jakubíková, J. As, S.V. Koning, T.D. Passali, D. Bouchikhi, N. Boufersaoui, A. Chinsky, A. Tortosa, S. Blasio, A.D. Rodríguez, V. Taire, D. Razetti, J. Mariotti, C.A. Ariel, A.H. Zanetta, A. Dario, F. Pabón, S.M. Quijano, A. Nieto, M.E. Bordino, L. Dallakyan, N. Dallakyan, D. Villca, N. Brkic, F. Umihanic, S. Reis, M. Manrique, D. Nkodo, Y. Ludemann, J. Chengpeng, J. Puentes, O.U.B. Mladina, R. De La Rosa, E.G. Kalakouta, O. Melis, A. Zeitouni, F. Máchalová, M. Slapak, J. Pecková, P. Caye-Thomasen, P. Chacon, F.S. Parker, J. Elsheikh, E. Ragab, A. Pitkäranta, A. Necker, P.C. Derelle, J. Duwelz, M. Francois, M. Pezzettigotta, S. Righini, C. Chkhaidze, I. Bernhard, R. Jahnke, V. Onder, G. Zieriacks, P. Siegfried, K. Koitschev, A. Kalampoki, V. Simasko, N. Skoulakis, C. Gulati, A. Nimbalkar, S. Sharma, Y. Squicciarini, M. Damasco, M. Camaioni, A. Cutrone, C. Gaudini, E. Grassom, D. Messi, G. Mansi, N. Orlando, C. Preziosi, S. Sorrentini, I. Villari, G. Trozzi, M. Vigo, A. Passali, G.C. Passali, F.M. Piantanida, R. Giordano, C. Mercuri, L. Cecconi, A. Giovari, M. Calderini, E. Nishida, Y. Saito, T. Ussatayeva, G. De Hoyos Parra, R.A. Treviño Gonzalez, J.L. Ramayo, S. Ologe, F.E. Afolabi, O. Nasrullah, M. Melendez, A. Milanes, R. Chmielik, M. Belchior, T. Cobzeanu, M.D. Gheorghe, D.C. Iorgulescu, A. Toader, M. Codrut, C. Stankovic, K. Barkociová, J. Havelkova, B. Jakubikova, J. Koman, A. Zargi, M. Pumarola, F. Rubio, L. Peco, K.P. Stierna, P. Hsu, W.-C. Arj-Ong, S. Chomchai, C. Chotigavanich, C. Hoep, L. Rinkel, R. Berraies, A. Baskent, E.A. Erikci, V.S. Onerci, M. Graham, J. Khwaja, S. Raine, C. Haloob, N. Haedo, I.D.G. Mehta, D. Casselbrant, M. Toan, P.N. The Susy Safe Working Group
Abstract: Objectives: To provide an epidemiological framework of symptoms related to Foreign Body (FB) injuries due to Button Battery (BB). Methods: Data on BB ingestion/inhalation have been obtained from the ButtonBatteryDB. The ButtonBatteryDB is a database collecting information on BB injuries in children (0-18 years of age). Data on 348 BB injures have been derived from the Registry of Foreign Body Injuries "Susy Safe" (269 cases) and from published scientific literature reporting case reports of FB injuries (79 cases). Results: Most of injured children were male and BBs were found more often in the mouth/esophagus/stomach (ICD935) and in the nose (ICD932). Analyzing symptoms related to BB located in the esophagus/mouth/stomach, we found that children had higher probability of experiencing dysphagia (30.19%, 95% C.I. 17.83-42.55), fever and cough (26.42%, 95% C.I. 14.55-38.28), compared to the other symptoms. Referring to the probability that symptoms occurred simultaneously, fever and cough are more likely (3.72%, 95% C.I. 1.0-6-43) to jointly showing up in children with BB in mouth/esophagus/stomach (ICD935), followed by fever and dysphagia (2.66%, 95% C.I. 0.36-4.96) and by fever and irritability/crying, fever and drooling, dysphagia and irritability/crying (2.13% C.I. 0.00-4.19, 95% C.I.). Conclusions: These findings provide new insight in clinical presentation of BB injuries: the identification of unique patterns of symptoms related to BB injuries is useful to perform an early diagnosis (and to guarantee a prompt medical reaction), also when the injury is un-witnessed. © 2015 Elsevier Ireland Ltd.
Published: 2015

16. European position paper on endoscopic management of tumours of the nose, paranasal sinuses and skull base

Author: Lund V. J, Stammberger H, Nicolai P, Castelnuovo P, Beal T, Beham A, Bernal Sprekelsen M, Braun H, Cappabianca P, Carrau R, Cavallo L, Clarici G, Draf W, Esposito F, Fernandez Miranda J, Fokkens W, Gardner P, Gellner V, Hellquist H, Hermann P, Hosemann W, Howard D, Jones N, Jorissen M, Kassam A, Kelly D, Kurschel Lackner S, Leong S, McLaughlin N, Maroldi R, Minovi A, Mokry M, Onerci M, Ong Yew K, Prevedello D, Saleh H, Sehti DS, Simmen D, Snyderman C, Solares A, Spittle M, Stamm A, Tomazic P, TRIMARCHI , MATTEO, Unger F, Wormald PJ, Zanation A., Lund V., J, Stammberger, H, Nicolai, P, Castelnuovo, P, Beal, T, Beham, A, Bernal Sprekelsen, M, Braun, H, Cappabianca, P, Carrau, R, Cavallo, L, Clarici, G, Draf, W, Esposito, F, Fernandez Miranda, J, Fokkens, W, Gardner, P, Gellner, V, Hellquist, H, Hermann, P, Hosemann, W, Howard, D, Jones, N, Jorissen, M, Kassam, A, Kelly, D, Kurschel Lackner, S, Leong, S, Mclaughlin, N, Maroldi, R, Minovi, A, Mokry, M, Onerci, M, Ong Yew, K, Prevedello, D, Saleh, H, Sehti, D, Simmen, D, Snyderman, C, Solares, A, Spittle, M, Stamm, A, Tomazic, P, Trimarchi, Matteo, Unger, F, Wormald, Pj, and Zanation, A.
Abstract: Tumours affecting the nose, paranasal sinuses and adjacent skull base are fortunately rare. However, they pose significant problems of management due their late presentation and juxtaposition to important anatomical structures such eye and brain. The increasing application of endonasal endoscopic techniques to their excision offers potentially similar scales of resection but with reduced morbidity. The present document is intended to be a state-of-the art review for any specialist with an interest in this area 1. to update their knowledge of neoplasia affecting the nose, paranasal sinuses and adjacent skull base; 2. to provide an evidence-based review of the diagnostic methods; 3. to provide an evidence-based review of endoscopic techniques in the context of other available treatments; 4. to propose algorithms for the management of the disease; 5. to propose guidance for outcome measurements for research and encourage prospective collection of data. The importance of a multidisciplinary approach, adherence to oncologic principles with intent to cure and need for long-term follow-up is emphasised.
Published: 2010

17. The comparison of the quality of life and intranasal edema between the patients with or without nasal packing after septoplasty

Author: Kayahan, B., primary, Ozer, S., additional, Suslu, A. E., additional, Ogretmenoglu, O., additional, and Onerci, M., additional
Published: 2016
Full Text: View/download PDF

18. Non food foreign body injuries

Author: Slapak, I. Passali, F.M. Passali, G.C. Gulati, A. Gregori, D. Foltran, F. Ballali, S. Berchialla, P. Rodriguez, H. Zaupa, P. Spitzer, P. Demetriades, C. Sokolova, L. Petridou, E. D'Alessandro, A. Pais Clemente, M.A.C. Jakubíková, J. Van As, S. De Koning, T. Passali, D. Chinsky, A. Rodriguez, H. Brkic, F. Mladina, R. Kalakouta, O. Melis, A. Máchalová, M. Thomasen, P. Elsheikh, E. Ragab, A. Pitkäranta, A. Necker, P.C. Derelle, J. Duwelz, M. Francois, M. Pezzettigotta, S. Righini, C. Stephane, P. Bernhard, R. Jahnke, V. Onder, G. Zieriacks, P Kalampoki, V. Simasko, N. Skoulakis, C. Camaioni, A. Cutrone, C. Gaudini, C. Messi, G. Grasso, D. Orlando, C. Nicola Mansi Preziosi, S. Villari, .G Sorrentini, I. Trozzi, M. Vigo, A. Nishida, Y. Ussatayeva, G. De Hoyos, R. Ologe, F.E. Nasrullah, M. Melendez, A. Chmielik, M. Belchior, T. Cobzeanu, M.D. Gheorghe, D.C. Toader, M. Iorgulescu, A. Codrut, C. Barkociová, J. Havelkova, B. Zargi, M. Pumarola, F. Rubio, L. Stierna, P. Hsu, W.-C. Arj-Ong, S. Chomchai, C. Rinkel, R. Hoep, L. Baskent, E.A. Erikci, V.C. Onerci, M. Graham, J. Khwaja, S. Raine, C.
Abstract: Rationale and aim: The aim of the present study is to acquire a better understanding of Non Food Foreign Bodies (NFFB) injuries in children with particular regard to the quantification of the risk of complications and hospitalization associated with patient characteristics, FB features, FB location and circumstances of the accident, as emerging from the SUSY Safe Web-Registry. Methods: The present study uses data provided by the SUSY Safe Project, a DG SANCO co-funded project which was aimed to collect as many scientific data as possible regarding Foreign Bodies (FB) injuries in children aged 0-14 years and to serve as a basis for a knowledge-based consumer protection activity in the Europe market. FBs were characterized by size, shape and consistency. Descriptive statistics (absolute and relative number or median, I and III quartile according to the categorical or continuous variable, respectively) were calculated for each considered non food item characteristics; FB features distribution by children class age and site of obstruction were assessed. Two different outcomes were considered: hospitalization and complication. FBs which most frequently cause complications were identified. The association between children age, adult presence, object characteristics and outcomes was computed using crude odds ratios and the related 95% confidence intervals. Results: 16,878 FB injuries in children aged 0-14 yrs have been recorded in the Susy Safe databases. FB type was specified in 10,564 cases; among them 7820 (74%) were due to a non food item. Almost two thirds of injuries occurred in patients 3 years or more old. 53% of patients were males, while 47% were females. When injury happened, the great part of children (86%) was playing. Almost 30% (2339) of injuries happened under adults' supervision. Complications occurred in 299 cases and the most documented was infections (10% of cases) followed by perforation (5%). Conclusions: The inhalation/aspiration of a FB, as well as the ingestion and the insertion in the orifices of a FB may result in significant morbidity. Particularly, long-standing or hazardous foreign bodies can cause extensive damage. Some objects, because of their composition, contour, or location, are particularly hazardous: for instance, objects with sharp edges pose a significant risk of laceration and perforation, while fragments of toys have been found only in 2 cases. Parents are frequently unconscious of hazard related with some objects and they are not adequately able to promptly recognize dangerous objects and risky situations. Moreover, also clinicians seem to pay little attention to adult role in the dynamic of the accident: in fact in case series descriptions, data regarding adult presence are often under-reported. On the contrary, since many injuries to children cannot be prevented without some degree of active behavior on the part of parents, the dissemination of information regarding safe behaviors and the implementation of educational strategies aiming to improve parent's attention toward this issue could be fundamental in preventing injuries and need to be promoted by family pediatricians and health practitioners. © 2012 Elsevier Ireland Ltd.
Published: 2012

19. The Susy Safe project overview after the first four years of activity

Author: Gregori, D. Foltran, F. Ballali, S. Berchialla, P. Rodriguez, H. Zaupa, P. Spitzer, P. Demetriades, C. Sokolova, L. Jane Buzarov Petridou, E. D'Alessandro, A. Pais Clemente, M.A.C. Jakubíková, J. Van As, S. De Koning, T. Passali, D. Chinsky, A. Rodriguez, H. Brkic, F. Mladina, R. Kalakouta, O. Melis, A. Máchalová, M. Thomasen, P.C. Elsheikh, E. Ragab, A. Pitkäranta, A. Necker, P.C. Derelle, J. Duwelz, M. Francois, M. Pezzettigotta, S. Pezzettigotta Stephane Righini, C. Bernhard, R. Jahnke, V. Goktas Onder Zieriacks, P. Kalampoki, V. Simasko, N. Skoulakis, C. Camaioni, A. Cutrone, C. Gaudini, E. Grasso, D. Messi, G. Mansi, N. Orlando, C. Preziosi, S. Sorrentini, I. Villari, G. Trozzi, M. Vigo, A. Passali, G.C. Passali, F.M. Nishida, Y. Ussatayeva, G. De Hoyos, R. Ologe, F.E. Nasrullah, M. Melendez, A. Chmielik, M. Belchior, T. Cobzeanu, M.D. Gheorghe, D.C. Iorgulescu, A. Codrut, C. Toader, M. Barkociová, J. Havelkova, B. Zargi, M. Pumarola, F. Rubio, L. Stierna, P. Hsu, W.-C. Arj-Ong, S. Chomchai, C. Hoep, L. Rinkel, R. Baskent, E.A. Erikci, V.S. Onerci, M. Graham, J. Khwaja, S. Raine, C. Šlapäk, I.
Abstract: Objectives: to collect relevant, up-to-date, representative, accurate, systematic information, related to foreign bodies (FB) injuries. Methods: The "Susy Safe" registry, a DG SANCO co-funded project gathering data on choking in all EU Countries and beyond, was established in order to create surveillance systems for suffocation injuries able to provide a risk-analysis profile for each of the products causing the injury. Main findings after 4 years of activities are resumed here. Results: 16,878 FB injuries occurred in children aged 0-14 years have been recorded in the SUSY SAFE databases; 8046 cases have been reported from countries outside EU. Almost one quart of the cases involving very young children (less than one year of age) presented a FB located in bronchial tract, thus representing a major threat to their health. Esophageal foreign bodies are still characterizing injuries occurred to children younger than one year, in older children the most common locations are the ears and the nose. FB type was specified in 10,564 cases. Food objects represented the 26% of the cases, whereas non-food objects were the remaining 74%. Among food objects, the most common were bones, nuts and seed, whereas for the non-food objects pearls, balls and marbles were observed most commonly (29%). Coins were involved in 15% of the non-food injuries and toys represented the 4% of the cases. Conclusions: this data collection system should be been taken into consideration for the calculation of the risk of injuries in order to provide the EU Commission with all the relevant estimates on FB injuries. © 2012 Elsevier Ireland Ltd.
Published: 2012

20. Food foreign body injuries

Author: Sebastian van As, A.B. Yusof, A.M. Millar, A.J.W. Gregori, D. Foltran, F. Ballali, S. Berchialla, P. Rodriguez, H. Zaupa, P. Spitzer, P. Demetriades, C. Slapák, I. Sokolova, L. Petridou, E. D'Alessandro, A. Clemente, M.A.C.P. Jakubíková, J. As, S.V. Koning, T.D. Passali, D. Chinsky, A. Rodriguez, H. Brkic, F. Mladina, R. Kalakouta, O. Melis, A. Máchalová, M. Caye-Thomasen, P. Elsheikh, E. Ragab, A. Pitkäranta, A. Necker, P.C. Derelle, J. Duwelz, M. Francois, M. Pezzettigotta, S. Righini, C. Stephane, P. Buzarov, J. Bernhard, R. Jahnke, V. Onder, G. Zieriacks, P. Kalampoki, V. Simasko, N. Skoulakis, C. Camaioni, A. Cutrone, C. Gaudini, E. Grasso, D. Mansi, N. Messi, G. Orlando, C. Preziosi, S. Sorrentini, I. Trozzi, M. Vigo, A. Villari, G. Passali, G.C. Passali, F.M. Nishida, Y. Ussatayeva, G. Hoyos, R.D. Ologe, F.E. Nasrullah, M. Melendez, A. Chmielik, M. Belchior, T. Cobzeanu, M.D. Gheorghe, D.C. Iorgulescu, A. Caius-Codrut Toader, M. Barkociová, J. Havelkova, B. Zargi, M. Sebastian van As, A.B. Pumarola, F. Rubio, L. Stierna, P. Hsu, W.-C. Arj-Ong, S. Chomchai, C. Hoep, L. Rinkel, R. Baskent, E.A. Erikci, V.S. Onerci, M. Graham, J. Khwaja, S. Raine, C.
Abstract: Rationale and aim: The purpose of this study is to acquire a better understanding of Food Foreign Bodies (FFB) injuries in children characterizing the risk of complications and prolonged hospitalization due to food items according to patients' characteristics, circumstances of the accident, Foreign Body (FB) features and FB location, as emerging from the SUSY Safe Web-Registry. Methods: The present study uses data provided by the SUSY Safe Project, a DG SANCO co-funded project started in February 2005, which was aimed at establishing an international registry of cases of Foreign Bodies (FB) injuries in children aged 0-14 years. The analysis was carried out on injuries due to a food item.FB location was reported according to ICD9-CM code: ears (ICD931), nose (ICD932), pharynx and larynx (ICD933) trachea, bronchi and lungs (ICD934), mouth, esophagus and stomach (ICD935).Age and gender injury distributions were assessed. Data regarding adult supervision and activity before injury were also evaluated. FBs which most frequently cause complications were identified. The association between children age, adult presence, object characteristics and hospitalization/complications was computed using unweighted odds ratios and the related 95% confidence intervals. Results: 16,878 FB injuries occurred in children aged 0-14 years have been recorded in the SUSY Safe databases. FB type was specified in 10,564 cases; among them 2744 (26%) were due to a food item. FB site was recorded in 1344 cases: FB was located in the ears in 99 patients, while 1140 occurred in the upper and lower respiratory tract; finally, 105 food items were removed from mouth, esophagus and stomach. Complications occurred in 176 cases and the most documented was pulmonary or bronchial infections (23%) followed emphysema or atelectasis and by and asthma (7%). Bones were the commonest retrieved FFB encountered in this study, while nuts seem to be the FFB most frequently associated to complications. Conclusions: On the basis of this study we make the strong recommendation that parents should be adequately educated and provide age-appropriate food to their children and be present in order to supervise them during eating especially during a critical period ranging from 2 to 3 years of age. © 2012 Elsevier Ireland Ltd.
Published: 2012

21. Stationery injuries in the upper aerodigestive system: Results from the Susy Safe Project

Author: Foltran, F. Berchialla, P. Gregori, D. Pitkäranta, A. Slapak, I. Jakubíková, J. Bellussi, L. Passali, D. Foltran, F. Ballali, S. Rodriguez, H. Zaupa, P. Spitzer, P. Demetriades, C. Šlapák, I. Sokolova, L. Petridou, E. D'Alessandro, A. Clemente, M.A.P.C. Jakubíková, J. Van As, S. De Koning, T. Passali, D. Chinsky, A. Rodriguez, H. Brkic, F. Mladina, R. Kalakouta, O. Melis, A. Máchalová, M. Caye-Thomasen, P. Elsheikh, E. Ragab, A. Pitkäranta, A. Necker, P.C. Derelle, J. Duwelz, M. Francois, M. Pezzettigotta, S. Righini, C. Stephane, P. Buzarov, J. Bernhard, R. Jahnke, V. Onder, G. Zieriacks, P. Kalampoki, V. Simasko, N. Skoulakis, C. Camaioni, A. Cutrone, C. Gaudini, E. Grasso, D. Mansi, N. Messi, G. Orlando, C. Preziosi, S. Sorrentini, I. Trozzi, M. Vigo, A. Villari, G. Passali, G.C. Passali, F.M. Nishida, Y. Ussatayeva, G. Hoyos, R.D. Ologe, F.E. Nasrullah, M. Melendez, A. Chmielik, M. Belchior, T. Cobzeanu, M.D. Gheorghe, D.C. Iorgulescu, A. Caius-Codrut Toader, M. Barkociová, J. Havelkova, B. Zargi, M. Pumarola, F. Rubio, L. Stierna, P. Hsu, W.-C. Arj-Ong, S. Chomchai, C. Hoep, L. Rinkel, R. Baskent, E.A. Erikci, V.S. Onerci, M. Graham, J. Khwaja, S. Raine, C.
Abstract: Rationale and aim: Foreign body (FB) injuries are a relatively frequent event in young children. Clinical picture can be evidently affected from different variables. Among those size, shape, type and FB location cover an important issue. Increased attempts have been made in order to encourage normative interventions for products devoted to children's care and entertainment, reaching acceptable safety level; on the contrary, fewer efforts have been devoted to investigate the risk associated to objects that - even if not expressly created for children - are easy accessed by children, like stationery.The aim of the present study is to characterize the risk of complications and prolonged hospitalization due to stationery items according to age and gender of patients, FB characteristics and FB location, circumstances of the accident, as emerging from the Susy Safe Registry. Methods: From 2005 to 2010 case were collected from 70 centers in 32 different countries. Details on the injuries, identified by means of the International Classification of Diseases, Ninth Revision (ICD-9) codes listed on hospital discharge records, were gathered through a standardized case report form, that provides a full set of information on injuries, with specific details on age and gender of the child, location, shape, volume, consistency and ellipticity of the foreign body, behavioral aspects linked to the injury, like the supervision of the parents or the activity concomitant to the accident, any complication occurred, length of hospitalization. Results: In the years 2005-2010 a total of 17,205 FB injuries in children aged 0-14. years were registered in Susy Safe Database. Among them 425 (2.5%) were due to a stationery item. The majority of FBs were retrieved in the nose (179, meaning 42.1%) and in the ears (176, 41.4%) only 5 cases were observed in children younger than 1. year, while most of the cases, 80.6%, were recorded in children older than 3. years. 193 patients (45.4%) were female, while 232 (54.6%) were male. Adult supervision was indicated in 212 cases. In 143 of these accidents the adult was present (33.6% of the whole group). The most frequent stationery retrieved was rubber, counting for 209 cases (49.2%). According to the FBs types, mostly all cases reported a 3D volume and a rigid or semirigid consistency (49.3%). Looking to the outcomes, 31 (7%) children needed hospitalization and complications were seen in 38 children (8.9%). No significant associations were seen between the outcomes and the FBs' characteristics, excluded those between the consistency of the FB (rigid) and the necessity of hospitalization and the shape (2D) and the presence of complication. Conclusions: Injuries are events that in many cases can be prevented with appropriate strategies. Passive environmental strategies, including product modification by manufacturers, are the most effective. However, regulation regarding small parts of potentially dangerous objects covers products addressed to children use but objects not projected for children, such as stationary items, are excluded. Our study testifies that stationary is involved in a non-negligible percentage of FB injuries, mainly due to insertion in the ears. Frequently, injuries happen under adult supervision. These results confirm the fact that when passive preventive strategies are not practical, active strategies that promote behavior change are necessary and information about this issue should be included in all visits to family pediatricians. © 2012 Elsevier Ireland Ltd.
Published: 2012

22. European Position Paper on Endoscopic Management of Tumours of the Nose, Paranasal Sinuses and Skull Base

Author: Lund, V. J., Stammberger, H., Nicolai, P., Castelnuovo, PAOLO GIOCONDO MARIA, Beal, T., Beham, A., Bernal Sprekelsen, M., Braun, H., Cappabianca, P., Carrau, R., Cavallo, L., Clarici, G., Draf, W., Esposito, F., Fernandez Miranda, J., Fokkens, W., Gardner, P., Gellner, V., Hellquist, H., Hermann, P., Hosemann, W., Howard, D., Jones, N., Jorissen, M., Kassam, A., Kelly, D., Kurschel Lackner, S., Leong, S., Mclaughlin, N., Maroldi, R., Minovi, A., Mokry, M., Onerci, M., Ong, Y. K., Prevedello, D., Saleh, H., Sehti, D. S., Simmen, D., Snyderman, C., Solares, A., Spittle, M., Stamm, A., Tomazic, P., Trimarchi, M., Unger, F., Wormald, P. J., and Zanation, A.
Subjects: Adult, Child, Preschool, Nose Neoplasms, Critical Pathways, Humans, Endoscopy, Skull Base Neoplasms, Algorithms, Paranasal Sinus Neoplasms
Abstract: Tumours affecting the nose, paranasal sinuses and adjacent skull base are fortunately rare. However, they pose significant problems of management due their late presentation and juxtaposition to important anatomical structures such eye and brain. The increasing application of endonasal endoscopic techniques to their excision offers potentially similar scales of resection but with reduced morbidity. The present document is intended to be a state-of-the art review for any specialist with an interest in this area 1. to update their knowledge of neoplasia affecting the nose, paranasal sinuses and adjacent skull base; 2. to provide an evidence-based review of the diagnostic methods; 3. to provide an evidence-based review of endoscopic techniques in the context of other available treatments; 4. to propose algorithms for the management of the disease; 5. to propose guidance for outcome measurements for research and encourage prospective collection of data. The importance of a multidisciplinary approach, adherence to oncologic principles with intent to cure and need for long-term follow-up is emphasised.
Published: 2010

23. nm23 Protein expression in larynx cancer and the relationship with metastasis

Author: Gunduz, M, primary, Ayhan, A, additional, Gullu, I, additional, Onerci, M, additional, Hosal, A.S, additional, Gursel, B, additional, Hosal, I.N, additional, and Firat, D, additional
Published: 1997
Full Text: View/download PDF

24. Atlantoaxial subluxation after tonsillectomy and adenoidectomy

Author: ONERCI, M, primary, OGRETMENOGLU, O, additional, and OZCAN, O, additional
Published: 1997
Full Text: View/download PDF

25. Nasal pepsin assay and pH monitoring in chronic rhinosinusitis.

Author: Ozmen S, Yucel OT, Sinici I, Ozmen A, Suslu AE, Ogretmenoglu O, and Onerci M
Published: 2008

26. Reappraisal of probing of the congenital obstruction of the nasolacrimal system: is nasal endoscopy essential?

Author: Sener, E. C. and Onerci, M.
Published: 2001
Full Text: View/download PDF

27. Necrotizing Otitis Externa, Otitis Media, Peripheral Facial Paralysis, And Brain Abscess in a Thalassemic Child After Allogeneic Bmt

Author: Tezcan, I., Tuncer, A. M., Yenicesu, I., Cetin, M., Ceyhan, M., Onerci, M., and Ariyurek, M.
Abstract: Severe infection is one of the major complications in the early and late post—bone marrow transplantation period. The authors report a thalassemic child who developed necrotizing otitis externa and otitis media, a very rare complication after bone marrow transplantation, and then peripheral facial nerve paralysis and brain abscess in the early period of bone marrow transplantation despite antibacterial and antifungal prophylaxis. Necrotizing otitis media is characterized by necrosis and sloughing of considerable areas in the middle ear and adjacent tissues and is an unusual disorder because of today's antibiotics. Granulocytopenia and background ear tissue exposed to previous repeated otitis media attacks may be the predisposing factors in this case. The authors conclude that the children with previous histories of recurrent otitis media should be prepared and monitored very carefully during bone marrow transplantation because of the risk of necrotizing otitis media, especially in the granulocytopenic period.
Published: 1998
Full Text: View/download PDF

28. A newborn's nose from the 6th millennium BC in Catal Huyuk

Author: Pirsig, W. and Onerci, M.
Published: 2000
Full Text: View/download PDF

29. THE ROLE OF INFLAMMATORY CELLS, ADHESION MOLECULES, INTERMEDIATE FILAMENTS AND CHEMOKINE RECEPTORS IN THE PATHOGENESIS OF NASAL POLYPS

Author: Onerci, M., Elsurer, C., Guzel, E. E., and Attila Dagdeviren

30. Mysinusitiscoach: Patient empowerment in chronic rhinosinusitis using mobile technology*

Author: Seys, S. F., Bousquet, J., Bachert, C., Fokkens, W. J., Agache, I., Manuel Bernal-Sprekelsen, Callebaut, I., Cardel, L. O., Carrie, S., Castelnuovo, P., Cathcart, R., Constantinidis, J., Cools, L., Cornet, M., Clement, G., Sousa, J. C., Cox, T., Doulaptsi, M., Gevaert, P., Hopkins, C., Hox, V., Hummel, T., Hosemann, W., Jacobs, R., Jorissen, M., Landis, B. N., Leunig, A., Lund, V. J., Mullol, J., Onerci, M., Palkonen, S., Proano, I., Prokopakis, E., Ryan, D., Riechelmann, H., Saevels, J., Segboer, C., Speleman, K., Steinsvik, E. A., Surda, P., Tomazic, P. V., Vanderveken, O., Gerven, L., Zele, T., Verhaeghe, B., Vierstraete, K., Vlaminck, S., Wilkinson, J., Williams, S., Pugin, B., Hellings, P. W., Universidade do Minho, Ear, Nose and Throat, AII - Inflammatory diseases, Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc-Roussillon (MACVIA-LR), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Université Montpellier 1 (UM1)-Centre Hospitalier Universitaire de Nîmes (CHU Nîmes)-European Innovation Partnership on Active and Healthy Ageing Reference Site (EIP on AHA), Commission Européenne-Commission Européenne-Organisation Mondiale de la Santé / World Health Organization Office (OMS / WHO)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Ghent University Hospital, Transilvania University of Brasov, Thérapeutique Recombinante Expérimentale (TIMC-IMAG-TheREx), Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications, Grenoble - UMR 5525 (TIMC-IMAG), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Laboratoire de parasitologie-mycologie, CHU Grenoble, Laboratoire d'Annecy-le-Vieux de Physique Théorique (LAPTH), Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), University of Barcelona, University of Edinburgh, and UCL - (SLuc) Service d'oto-rhino-laryngologie
Subjects: self-management, [SDV]Life Sciences [q-bio], Medicina Básica [Ciências Médicas], 03 medical and health sciences, 0302 clinical medicine, Quality of life (healthcare), Health care, otorhinolaryngologic diseases, medicine, Humans, Sinusitis, Patient participation, 030223 otorhinolaryngology, rhinosinusitis, Rhinitis, Computer. Automation, education, Science & Technology, Self-management, business.industry, Health technology, General Medicine, Evidence-based medicine, mobile application, medicine.disease, Precision medicine, Mobile Applications, 3. Good health, Self Care, chronic airway disease, 030228 respiratory system, Otorhinolaryngology, Chronic Disease, Ciências Médicas::Medicina Básica, Quality of Life, Position paper, Human medicine, Medical emergency, Patient Participation, business
Abstract: Mobile health technology is emerging to take a prominent position in the management of chronic diseases. These technologies aim at enhancing patient empowerment via education and self-management. To date, of all the different apps available for patients with sinus disease, none were developed by medical experts dealing with chronic rhinosinusitis (CRS). The European Forum for Research and Education in Allergy and Airway diseases (EUFOREA) has undertaken a multi-stakeholder approach for designing, developing and implementing a tool to support CRS patients in monitoring their symptoms and to provide patients with a digital support platform containing reliable medical information about their disease and treatment options. mySinusitisCoach has been developed by medical experts dealing with CRS in close collaboration with patients, primary care physicians and community pharmacists, meeting the needs of both patients and health care providers. From a research perspective, the generation of real life data will help to validate clinical studies, patient stratification and improve understanding of the socio-economic impact of CRS, thereby paving the way for better treatment strategies., info:eu-repo/semantics/publishedVersion

31. European position paper on endoscopic management of tumours of the nose, paranasal sinuses and skull base

Author: Lund, V. J., Stammberger, H., Nicolai, P., Paolo Castelnuovo, Beal, T., Beham, A., Bernal-Sprekelsen, M., Braun, H., Cappabianca, P., Carrau, R., Cavallo, L., Clarici, G., Draf, W., Esposito, F., Fernandez-Miranda, J., Fokkens, W., Gardner, P., Gellner, V., Hellquist, H., Hermann, P., Hosemann, W., Howard, D., Jones, N., Jorissen, M., Kassam, A., Kelly, D., Kurschel-Lackner, S., Leong, S., Mclaughlin, N., Maroldi, R., Minovi, A., Mokry, M., Onerci, M., Ong, Y. K., Prevedello, D., Saleh, H., Sehti, D. S., Simmen, D., Snyderman, C., Solares, A., Spittle, M., Stamm, A., Tomazic, P., Trimarchi, M., Unger, F., Wormald, P. J., Zanation, A., and European Rhinologic Society Advisory Board on Endoscopic Techniques

32. Liposarcoma of the cheek: report of a case.

Author: Ruacan, Sevket, Öerci, Metin, Gediko&gsline;lu, Gökhan, Dal, Teoman, Ruacan, S, Onerci, M, Gedikoglu, G, and Dal, T
Subjects: LIPOSARCOMA, MOUTH, TUMORS, ADIPOSE tissue cancer, CHEEK, MOUTH tumors, ORAL mucosa
Abstract: Liposarcomas of the head and neck region are rare. Those originating in the buccal mucosa cause special diagnostic and therapeutic difficulties. In this report, a predominantly well-differentiated liposarcoma of the cheek in a 32-yr- old man is reported. The tumor continued to grow slowly over a period of 3 yr before definitive diagnosis was established. Radical maxillectomy was performed with total excision of the tumor. Recommendations for earlier and correct diagnosis and treatment of this rare neoplasm are discussed. [ABSTRACT FROM AUTHOR]
Published: 1993
Full Text: View/download PDF

33. Endoscopic Lateral Osteotomy in Rhinoplasty.

Author: Altunay ZO and Onerci M
Subjects: Ecchymosis etiology, Edema, Endoscopy, Humans, Osteotomy, Postoperative Complications, Rhinoplasty
Abstract: Objectives: The purpose of this study was to investigate the advantages of endoscopic lateral osteotomy, to evaluate the effects of the periosteal elevation on ecchymosis and to search the reasons for the ecchymosis and the intranasal mucosal tears., Methods: On a randomly chosen side a subperiosteal tunnel was elevated, on the other side a subperiosteal tunnel was not elevated. Bilateral lateral osteotomies were performed. Internal nasal packing was not used. The post-operative care was similar for all patients. The patients were evaluated on the third post-operative day. The intranasal mucosal tears, the lateral osteotomy cut on the periosteal elevation side were examined using endoscopes. The degree of ecchymosis was determined by 2 other surgeons, who were unaware of the elevated side, using the grading system adapted from Hoffman et al., Results: The intranasal mucosal injury was seen in 16 of non-elevated side whereas it was 14 on the periosteal elevated side. Endoscopy showed the perforating arteries and elevation of the periosteum caused rupture and oozing from these arteries which might be a cause for ecchymosis. Ecchymosis was more severe on the side with subperiosteal tunnel in 6 patients; whereas only in 2 patients it was more severe on the side with no subperiosteal tunnel elevation while in 12 patients the degree of ecchymosis was the same on both sides., Conclusion: Endoscopy gives a great opportunity to visualize the lateral osteotomy site. Besides the lateral osteotomy cut, the arteries and the intranasal mucosal injury can be visualized. Periost elevation increases the severity of ecchymosis due to the rupture of the perforating arteries, not due to the trauma of the angular artery. Intramucosal tears do not increase the severity of the ecchymosis., Competing Interests: The authors have no conflicts of interest to disclose., (Copyright © 2020 by Mutaz B. Habal, MD.)
Published: 2021
Full Text: View/download PDF

34. Real-life assessment of chronic rhinosinusitis patients using mobile technology: The mySinusitisCoach project by EUFOREA.

Author: Seys SF, De Bont S, Fokkens WJ, Bachert C, Alobid I, Bernal-Sprekelsen M, Bjermer L, Callebaut I, Cardell LO, Carrie S, Castelnuovo P, Cathcart R, Constantinidis J, Cools L, Cornet M, Clement G, Cox T, Delsupehe L, Correia-de-Sousa J, Deneyer L, De Vos G, Diamant Z, Doulaptsi M, Gane S, Gevaert P, Hopkins C, Hox V, Hummel T, Hosemann W, Jacobs R, Jorissen M, Kjeldsen A, Landis BN, Lemmens W, Leunig A, Lund V, Mariën G, Mullol J, Onerci M, Palkonen S, Proano I, Prokopakis E, Ryan D, Riechelmann H, Sahlstrand-Johnson P, Salmi-Toppila S, Segboer C, Speleman K, Steinsvik A, Surda P, Tomazic PV, Vanderveken O, Van Gerven L, Van Zele T, Verfaillie J, Verhaeghe B, Vierstraete K, Vlaminck S, Wagenmann M, Pugin B, and Hellings PW
Subjects: Chronic Disease, Cross-Sectional Studies, Humans, Quality of Life, Nasal Polyps epidemiology, Rhinitis diagnosis, Rhinitis epidemiology, Sinusitis diagnosis, Sinusitis epidemiology
Abstract: Background: Chronic rhinosinusitis (CRS) is a chronic inflammatory disease associated with a substantial personal and socioeconomic burden. Monitoring of patient-reported outcomes by mobile technology offers the possibility to better understand real-life burden of CRS., Methods: This study reports on the cross-sectional evaluation of data of 626 users of mySinusitisCoach (mSC), a mobile application for CRS patients. Patient characteristics of mSC users were analysed as well as the level of disease control based on VAS global rhinosinusitis symptom score and adapted EPOS criteria., Results: The mSC cohort represents a heterogeneous group of CRS patients with a diverse pattern of major symptoms. Approximately half of patients reported nasal polyps. 47.3% of all CRS patients were uncontrolled based on evaluation of VAS global rhinosinusitis symptom score compared to 40.9% based on adapted EPOS criteria. The impact of CRS on sleep quality and daily life activities was significantly higher in uncontrolled versus well-controlled patients. Half of patients had a history of FESS (functional endoscopic sinus surgery) and reported lower symptom severity compared to patients without a history of FESS, except for patients with a history of more than 3 procedures. Patients with a history of FESS reported higher VAS levels for impaired smell., Conclusion: Real-life data confirm the high disease burden in uncontrolled CRS patients, clearly impacting quality of life. Sinus surgery improves patient-reported outcomes, but not in patients with a history of more than 3 procedures. Mobile technology opens a new era of real-life monitoring, supporting the evolution of care towards precision medicine., (© 2020 The Authors. Allergy published by European Academy of Allergy and Clinical Immunology and John Wiley & Sons Ltd.)
Published: 2020
Full Text: View/download PDF

35. European position paper on the anatomical terminology of the internal nose and paranasal sinuses.

Author: Lund VJ, Stammberger H, Fokkens WJ, Beale T, Bernal-Sprekelsen M, Eloy P, Georgalas C, Gerstenberger C, Hellings P, Herman P, Hosemann WG, Jankowski R, Jones N, Jorissen M, Leunig A, Onerci M, Rimmer J, Rombaux P, Simmen D, Tomazic PV, Tschabitscherr M, and Welge-Luessen A
Subjects: Endoscopy, Europe, Humans, Nose surgery, Paranasal Sinuses surgery, Nose anatomy & histology, Paranasal Sinuses anatomy & histology, Terminology as Topic
Abstract: The advent of endoscopic sinus surgery led to a resurgence of interest in the detailed anatomy of the internal nose and paranasal sinuses. However, the official Terminologica Anatomica used by basic anatomists omits many of the structures of surgical importance. This led to numerous clinical anatomy papers and much discussion about the exact names and definitions for the structures of surgical relevance. This European Position Paper on the Anatomical Terminology of the Internal Nose and Paranasal Sinuses was conceived to re-evaluate the anatomical terms in common usage by endoscopic sinus surgeons and to compare this with the official Terminologica Anatomica. The text is a concise summary of all the structures encountered during routine endoscopic surgery in the nasal cavity, paranasal sinuses and at the interface with the orbit and skull base but does not provide a comprehensive text for advanced skull base surgery. It draws on a detailed review of the literature and provides a consensus where several options are available, defining the anatomical structure in simple terms and in English. It is recognised that this is an area of great variation and some indication of the frequency with which these variants are encountered is given in the text and table. All major anatomical points are illustrated, drawing on the expertise of the multi-national and multi-disciplinary contributors to this project.
Published: 2014

36. Management of cerebrospinal fluid leak during endoscopic pituitary surgery.

Author: Berker M, Aghayev K, Yücel T, Hazer DB, and Onerci M
Subjects: Adolescent, Adult, Aged, Cerebrospinal Fluid Leak, Cerebrospinal Fluid Rhinorrhea etiology, Cerebrospinal Fluid Rhinorrhea surgery, Dura Mater surgery, Female, Humans, Male, Middle Aged, Natural Orifice Endoscopic Surgery adverse effects, Surgical Flaps, Wound Closure Techniques, Young Adult, Adenoma surgery, Cerebrospinal Fluid Rhinorrhea prevention & control, Natural Orifice Endoscopic Surgery methods, Neurosurgical Procedures methods, Pituitary Neoplasms surgery
Abstract: Objective: Dural opening and closures are major steps in endoscopic pituitary surgery. Restoring the normal anatomy at the end of the procedure creates a natural barrier between the intrasellar compartment and the sinonasal cavity., Methods: In this study, we present a relatively simple dural opening and closure technique for endoscopic pituitary surgery. This technique provides a better alternative to the use of a more complex nasoseptal flap or the multilevel closure with artificial materials as it restores the normal anatomy after the tumor removal and provides a better physiological barrier between the sinonasal cavity and the intrasellar compartment. Incision is performed in circular or horseshoe fashion leaving a small peduncle, and then the dura is reflected., Results: Of the 733 endoscopic transsphenoidal procedures in 667 patients conducted between January 2006 and May 2012, we used this described technique in 50 cases (7.4%). In these 50 cases with dural flap, there was no postoperative CSF leakage. Intraoperative CSF leakage was observed in 135 (20.2%) of the 667 patients. In 15 (11.1%) of these 135 patients we used the dural flap technique accompanied with fat and/or fascia lata support. There was no postoperative leakage in these patients. In the remaining 120 (89.9%) patients who had intraoperative CSF leakage, we used fat and/or fascia lata for the reconstruction of the sella floor. But we observed postoperative CSF leakage in 12 (10%) of the 120 patients without the dural flap which were reoperated., Conclusion: The dural flap technique we employ has several advantages. First of all, it allows optimal physiological reconstruction after the surgery. Secondly, the bridge between the flap and the main dura helps maintain the vascular supply, which in turn can radically shorten the healing time. Thirdly, this technique is obviously a better alternative to the time consuming and expensive multilevel closures with tissue sealants and artificial grafts., (Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.)
Published: 2013
Full Text: View/download PDF

37. Orbital chondrosarcoma arising from paranasal sinuses.

Author: Kiratli H, Dikmetaş O, Tarlan B, and Onerci M
Subjects: Adult, Aged, Chondrosarcoma pathology, Female, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Orbital Neoplasms pathology, Paranasal Sinus Neoplasms pathology, Tomography, X-Ray Computed, Chondrosarcoma diagnosis, Orbital Neoplasms diagnosis, Paranasal Sinus Neoplasms diagnosis
Abstract: Orbital chondrosarcoma arising from paranasal sinuses or from the nasal cavity with orbital extension is highly unusual. The aim of this report is to describe our multidisciplinary experience in the treatment of three patients with extensive sino-orbital chondrosarcomas. The patients were aged 43, 75 and 63 years, and the tumors originated from the maxillary, sphenoidal, and ethmoidal sinuses, respectively. Magnetic resonance imaging studies showed homogeneously hypointense lesions on T1-weighted scans, which were hyperintense on T2-weighted images. Intranasal endoscopic surgery alone or in combination with other conventional surgical approaches was the main therapeutic choice. Two patients had recurrences treated with wider surgical removal. Fractionated stereotactic radiotherapy was used in two cases. Two patients had histopathological grade I tumor and one had grade III chondrosarcoma. No patient had regional spread or distant metastasis. All patients were disease-free at 4, 2, and 3 years, respectively, following their last therapeutic interventions. Endoscopic surgery results in lesser morbidity for chondrosarcomas arising from paranasal sinuses and extending into posterior parts of the orbit. However, because control of surgical margins may not be complete, recurrences may occur justifying more radical approaches.
Published: 2013
Full Text: View/download PDF

38. Complications of endoscopic surgery of the pituitary adenomas: analysis of 570 patients and review of the literature.

Author: Berker M, Hazer DB, Yücel T, Gürlek A, Cila A, Aldur M, and Onerci M
Subjects: Adenoma diagnosis, Adolescent, Adult, Cerebrospinal Fluid Rhinorrhea etiology, Diabetes Insipidus etiology, Female, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Nose surgery, Pituitary Neoplasms diagnosis, Retrospective Studies, Sphenoid Sinusitis etiology, Adenoma surgery, Endoscopy adverse effects, Pituitary Neoplasms surgery, Postoperative Complications etiology
Abstract: Endoscopic transsphenoidal surgery is emerging as a minimally invasive and maximally effective procedure for pituitary adenomas. In this report we analyzed the complications in 624 procedures of endonasal transsphenoidal endoscopic surgery in the treatment of 570 patients with pituitary adenomas. The leading author (MB) operated pituitary adenomas via pure endoscopic endonasal transsphenoidal surgery between January 2006 and August 2011 at the Hacettepe University, Department of Neurosurgery in Ankara. Complications were assessed in 624 surgical procedures under five groups; rhinological, CSF leaks, infection, vascular and endocrinologic complications. We observed a total of 76 complications (12.1%). Rhinological complications occurred in 8 patients (1.3%): 4 epistaxis (0.6%) and 4 hyposmia (0.6%). Postoperative CSF leaks occurred in 8 patients (1.3%), and infectious complications occurred in 8 patients: 3 cases of sphenoidal sinusitis (0.4%), 5 cases of meningitis (0.8%). Only 1 case of internal carotid aneurysm rupture during the opening of sellar floor (0.16%) was observed. Endocrinologic complications occurred in 51 (8.1%) patients: Anterior pituitary deficiency in 12 (1.9%), transient diabetes insipidus (DI) in 29 (4.6%), permanent DI in 3 (0.4%) and inappropriate antidiuretic hormone secretion syndrome occurred in 7 (1.1%). There was no mortality directly related to the surgical procedure. The complication rates observed in our study suggests that the endoscopic pituitary surgery is at least as safe as microscopic transphenoidal surgery. These rates were obtained with due experience and well-coordinated teamwork. To further improve these rates, new technological developments will be helpful.
Published: 2012
Full Text: View/download PDF

39. Distribution of inflammatory cells, adhesion molecules, intermediate filaments, and chemokine receptors in subgroups of nasal polyp patients.

Author: Onerci M, Elsurer C, Guzel EE, and Dagdeviren A
Subjects: Adult, Antigens, CD genetics, Biomarkers metabolism, Cell Adhesion Molecules genetics, Cell Adhesion Molecules immunology, Female, Gene Expression Profiling, Humans, Immunohistochemistry, Intermediate Filaments genetics, Intermediate Filaments immunology, Male, Middle Aged, Receptors, Chemokine genetics, Receptors, Chemokine immunology, Antigens, CD metabolism, Cell Adhesion Molecules metabolism, Intermediate Filaments metabolism, Nasal Polyps immunology, Receptors, Chemokine metabolism
Abstract: Background: The pathogenesis of nasal polyps (NPs) is incompletely understood. The aim of this study was to investigate the distribution of inflammatory cells, adhesion molecules, intermediate filaments, and chemokine receptors in subgroups of NP patients., Methods: In total, 35 patients were enrolled (group 1, 10 patients with Samter syndrome; group 2, 10 patients with diffuse polyposis without signs of Samter syndrome; group 3: 5 patients with solitary nasal polyps; group 4, 10 controls). Immunohistochemical staining was performed for CD105, CD106, CD62E, CD4, CD8, CXCR4, CD147, CD90, CD104, BF45, vimentin, pancytokeratin, and muscle-specific actin (MSA) in all patients' specimens., Results: Expression of CD4, CD8, and CD106 were similar between the groups. Number of patients expressing CD4 in groups 1, 2, and 3 were higher than the controls. Number of patients expressing CD8 antigen were significantly higher in all three groups than in the control group. Expression of CD147 in groups 3 and 4 was significantly higher than in groups 1 and 2. CD98 expression was higher in groups 1, 2, and 3 than in group 4. The number of patients expressing vimentin in groups 1, 2, and 3 was significantly higher than in group 4. Immunostaining for pancytokeratin was positive in all patients., Conclusion: In conclusion, inflammatory cell, adhesion molecule, intermediate filament, and chemokine receptor profiles in nasal polyps differ among different patient groups and control subjects. Additional specific immunohistochemical studies are necessary for development of more specific immunotherapies.
Published: 2011
Full Text: View/download PDF

40. Overview of vascular complications of pituitary surgery with special emphasis on unexpected abnormality.

Author: Berker M, Aghayev K, Saatci I, Palaoğlu S, and Onerci M
Subjects: Adult, Female, Humans, Treatment Outcome, Carotid Artery Injuries etiology, Neurosurgical Procedures adverse effects, Pituitary Neoplasms surgery
Abstract: Arterial bleeding during transsphenoidal surgery for pituitary adenoma is known complication. This usually happens due to rupture of intracavernous carotid or delayed hemorrhage due to the carotico-cavernous fistula and/or pseudoaneurysm. There is also evidence that cavernous carotid aneurysms may occur with pituitary tumors, yet largest series failed to demonstrate any link between aneurysm formation and pituitary tumors. Usually such an aneurysm rupture results in formation of carotico-cavernous fistula. However, pituitary apoplexy and even epistaxis have been reported. In this paper we present a patient with recurrent pituitary adenoma and cavernous carotid artery aneurysm, which caused significant hemorrhage during the surgery. Although retrospective analysis of MRI disclosed that the patient had the aneurysm before the first surgery, it remained silent until the second operation. Therefore neurosurgeons should be very susceptive to any signal changes on preoperative MR images, especially in recurrent cases, where normal anatomical relations are disturbed by fibrotic tissue. Also, we reviewed the vascular complication of pituitary surgery based on the literature.
Published: 2010
Full Text: View/download PDF

41. European position paper on endoscopic management of tumours of the nose, paranasal sinuses and skull base.

Author: Lund VJ, Stammberger H, Nicolai P, Castelnuovo P, Beal T, Beham A, Bernal-Sprekelsen M, Braun H, Cappabianca P, Carrau R, Cavallo L, Clarici G, Draf W, Esposito F, Fernandez-Miranda J, Fokkens W, Gardner P, Gellner V, Hellquist H, Hermann P, Hosemann W, Howard D, Jones N, Jorissen M, Kassam A, Kelly D, Kurschel-Lackner S, Leong S, McLaughlin N, Maroldi R, Minovi A, Mokry M, Onerci M, Ong YK, Prevedello D, Saleh H, Sehti DS, Simmen D, Snyderman C, Solares A, Spittle M, Stamm A, Tomazic P, Trimarchi M, Unger F, Wormald PJ, and Zanation A
Subjects: Adult, Algorithms, Child, Preschool, Critical Pathways, Humans, Nose Neoplasms diagnosis, Nose Neoplasms epidemiology, Paranasal Sinus Neoplasms diagnosis, Paranasal Sinus Neoplasms epidemiology, Skull Base Neoplasms diagnosis, Skull Base Neoplasms epidemiology, Endoscopy methods, Nose Neoplasms surgery, Paranasal Sinus Neoplasms surgery, Skull Base Neoplasms surgery
Abstract: Tumours affecting the nose, paranasal sinuses and adjacent skull base are fortunately rare. However, they pose significant problems of management due their late presentation and juxtaposition to important anatomical structures such eye and brain. The increasing application of endonasal endoscopic techniques to their excision offers potentially similar scales of resection but with reduced morbidity. The present document is intended to be a state-of-the art review for any specialist with an interest in this area 1. to update their knowledge of neoplasia affecting the nose, paranasal sinuses and adjacent skull base; 2. to provide an evidence-based review of the diagnostic methods; 3. to provide an evidence-based review of endoscopic techniques in the context of other available treatments; 4. to propose algorithms for the management of the disease; 5. to propose guidance for outcome measurements for research and encourage prospective collection of data. The importance of a multidisciplinary approach, adherence to oncologic principles with intent to cure and need for long-term follow-up is emphasised.
Published: 2010

42. Craniocerebral injury resulting from pencil penetration.

Author: Ozer S, Onal B, Akbay A, and Onerci M
Subjects: Accidental Falls, Child, Preschool, Craniocerebral Trauma etiology, Craniocerebral Trauma surgery, Ethmoid Sinus diagnostic imaging, Humans, Male, Maxillary Sinus diagnostic imaging, Orbit diagnostic imaging, Tomography, X-Ray Computed, Wounds, Penetrating etiology, Wounds, Penetrating surgery, Craniocerebral Trauma diagnosis, Endoscopy methods, Ethmoid Sinus surgery, Maxillary Sinus injuries, Orbit injuries, Wounds, Penetrating diagnosis
Abstract: Penetrating craniofacial trauma in pediatric age group is quite rare. A case is reported that presented with a pencil penetration injury entering from the anterior maxillary sinus through the orbital medial wall, and ethmoidal cells and septum, reaching the contralateral gyrus rectus of the frontal lobe. All the vital structures were preserved. The patient was first treated with manual extraction of the pencil, without any immediate complications; however, rhinorrhea followed the procedure 4 h later. Early endoscopic surgical intervention was performed and the rhinorrhea was successfully treated in this case. This report discusses radiological and surgical characteristics of this unusual penetrating craniofacial trauma.
Published: 2010
Full Text: View/download PDF

43. Spontaneous involution of nasopharyngeal angiofibroma.

Author: Tosun F, Onerci M, Durmaz A, and Ugurel S
Subjects: Angiofibroma blood supply, Carotid Artery, Internal diagnostic imaging, Embolization, Therapeutic, Follow-Up Studies, Humans, Male, Maxillary Artery diagnostic imaging, Nasopharyngeal Neoplasms blood supply, Palate diagnostic imaging, Paranasal Sinus Neoplasms diagnostic imaging, Remission, Spontaneous, Sphenoid Bone diagnostic imaging, Sphenoid Sinus diagnostic imaging, Tomography, X-Ray Computed, Young Adult, Angiofibroma pathology, Nasopharyngeal Neoplasms pathology
Abstract: There are several studies addressing regression of residual nasopharyngeal angiofibroma after surgery, but spontaneous regression of this tumor has been reported in only 2 cases. We present a case of nasopharyngeal angiofibroma that has involuted spontaneously in the last 5 years. The tumor had been diagnosed at another institute. Computed tomography taken in 2002 had revealed the tumor occupying the entire sphenoid sinus and the pterygopalatine fossa, extending to the cavernous sinus and the infratemporal fossa on the right side. The vascularization of the tumor had been mainly from the internal maxillary artery on angiography. The internal maxillary artery had been occluded with a coil, but branches of internal carotid artery could not be embolized due to high risks of complications. In 2004 the patient was seen at our institute, and this time, repeated angiography revealed rich vascularization from the internal carotid artery. The patient did not accept any treatment and was put on follow-up. He had no complaint in January 2007. The tumor was seen to disappear completely, except a little remnant at the right pterygopalatine fossa on computed tomography. This is the third reported case in the literature with spontaneous regression of nasopharyngeal angiofibroma.
Published: 2008
Full Text: View/download PDF

44. An animal study on cartilage healing using auricular cartilage as a model.

Author: Haberal Can I, Atilla P, Cakar AN, and Onerci M
Subjects: Animals, Ear Cartilage pathology, Ear Cartilage transplantation, Female, Models, Animal, Ossification, Heterotopic, Rabbits, Wound Healing, Ear Cartilage physiopathology
Abstract: We investigated the effect of different surgical procedures on cartilage healing, using auricular cartilage as a model, which would be useful to create a rationale for septal cartilage surgery. Different kinds of manipulations were performed on the auricular cartilage of six female New Zealand white rabbits. Histopathological investigations were performed under light microscopy 4 months postoperatively. The autologous cartilage grafts survived well under the forehead skin regardless of the presence of the perichondrium. The response of perichondrium to either incomplete or complete trauma was not only new cartilage formation but also ossification. When incomplete incisions were made on the non-perichondrial side, new cartilage formation was stimulated whereas ossification was induced when there was perichondrium on the cartilage. If the cartilage with perichondrium was sliced into small pieces and planted back in its original place, many ossification areas occurred. The crushed cartilage was usually absorbed but sometimes replaced by bony plates. The traumatized cartilage with perichondrium undergoes ossification. This finding may be important clinically in that surgeons should not traumatize septal cartilage with perichondrium and work under the perichondrium. This ossification of traumatized cartilage may later result in thickening of the septal cartilage which we sometimes face in revision surgery.
Published: 2008
Full Text: View/download PDF

45. Juvenile nasopharyngeal angiofibroma: a revised staging system.

Author: Onerci M, Oğretmenoğlu O, and Yücel T
Subjects: Adolescent, Angiofibroma, Humans, Magnetic Resonance Imaging, Male, Nasopharyngeal Neoplasms diagnosis, Neoplasm Invasiveness, Neoplasm Recurrence, Local, Neoplasm Staging, Neoplasm, Residual, Paranasal Sinus Neoplasms diagnostic imaging, Paranasal Sinus Neoplasms pathology, Paranasal Sinus Neoplasms surgery, Tomography, X-Ray Computed, Nasopharyngeal Neoplasms pathology, Nasopharyngeal Neoplasms surgery
Abstract: Objectives: To discuss the shortcomings of current staging systems and to suggest modifications according to new surgical methods and data., Study Design: A retrospective chart review., Methods: The medical records of 36 patients, all of whom underwent resection of juvenile nasopharyngeal angiofibroma by external or endonasal approach between 1983 and 2002, were reviewed retrospectively. Follow-up period of patients ranged from 3 to 7 years (mean, 4.5 years). Tumour extent, sites and rate of persistent disease were analyzed and compared with the literature., Results: Persistent or recurrent disease was found in 12 of the 36 patients (33%). The primary tumour of these 12 cases invaded one or more anatomic region beside nasopharynx: the base of the pterygoid process in 9 cases (75%), the infratemporal fossa in 4 (33%), the pterygomaxillar fossa in 4 (33%), and the sphenoid sinus in 2 cases (17%). Involvement of the pterygoid process base was observed in only 3 of the 24 patients without persistent disease, whereas it was found 10 out of 12 patients with persistent disease., Conclusions: Advances in radiographic imaging, embolization, and surgical methods of treating angiofibromas have changed the sites associated with a high risk for persistent disease or morbidity. These changes have made it necessary for the authors to devise more appropriate classifications and, subsequently, several new staging systems were gradually introduced. Recent technological advances, particularly angled endoscopes, have resulted in improved exposure. In the light of all these recent advances, data from our series, and the literature, we suggested a new classification for determining the risk of persistent disease, choosing the appropriate surgical method, and for maintaining uniformity.
Published: 2006

46. Proliferation, angiogenesis and hormonal markers in juvenile nasopharyngeal angiofibroma.

Author: Saylam G, Yücel OT, Sungur A, and Onerci M
Subjects: Adolescent, Adult, Child, Female, Humans, Immunohistochemistry, Male, Proliferating Cell Nuclear Antigen metabolism, Receptors, Estrogen metabolism, Receptors, Progesterone metabolism, Retrospective Studies, Transforming Growth Factor beta metabolism, Vascular Endothelial Growth Factor A metabolism, Angiofibroma metabolism, Nasopharyngeal Neoplasms metabolism, Neoplasm Recurrence, Local metabolism
Abstract: Objectives: Juvenile nasopharyngeal angiofibroma (JNA) is a highly vascular and locally invasive tumor that exclusively affects male adolescents. Sex hormones are first discussed to clarify the etiology of JNA. Recently with the advances in the field of cell biology angiogenetic markers, proliferation markers and growth factors are investigated to identify the molecular basis of JNA as all neoplasm. In this study we tried to evaluate the expression of proliferation, angiogenesis and hormonal markers in JNA., Methods: Immunohistochemical analysis were performed on paraffin-embedded 27 JNA samples which were obtained from the patients operated at University of Hacettepe Department of Otorhinolaryngology, a tertiary care center. Estrogen receptor (ER), progesterone receptor (PR), proliferating cell nuclear antigen (PCNA), vascular endothelial growth factor (VEGF) and transforming growth factor beta (TGF-beta) specific antibodies were used and evaluated by light microscopy, Results: Two of 27 cases were ER positive. Nine of 27 cases were positive for PR. All of the cases were stained with PCNA. Twenty-four of 27 cases stained with VEGF. TGF-beta was positive in 14 of 27 cases. All recurrent cases were stained with PCNA and VEGF; just three of them were stained with TGF-beta., Conclusions: Hormonal markers ER and PR did not seem to play a role in pathogenesis of JNA. PCNA, VEGF and TGF-beta may play a role in the pathogenesis of JNA by promoting angiogenesis and proliferation, but this role did not seem to have a relation with hormonal markers.
Published: 2006
Full Text: View/download PDF

47. A rare complication of embolization in juvenile nasopharyngeal angiofibroma.

Author: Onerci M, Gumus K, Cil B, and Eldem B
Subjects: Angiofibroma diagnostic imaging, Angiography, Child, Humans, Male, Nasopharyngeal Neoplasms diagnostic imaging, Retina pathology, Visual Fields physiology, Angiofibroma pathology, Angiofibroma therapy, Embolization, Therapeutic methods, Nasopharyngeal Neoplasms pathology, Nasopharyngeal Neoplasms therapy
Abstract: Juvenile nasopharyngeal angiofibroma (JNA) is one of the most common benign nasal cavity tumors of adolescence. It exhibits a strong tendency to bleed and despite being microscopically benign, its behavior is locally aggressive. Preoperative embolization is helpful to minimize intraoperative bleeding. However, embolization procedure may have some important thromboembolic complications such as central retinal artery occlusion. In this article, a young male with juvenile nasopharyngeal angiofibroma, who lost his vision in the left eye following embolization was presented and the possible therapeutic options in such a complication were discussed.
Published: 2005
Full Text: View/download PDF

48. Prognostic significance of Langerhans cell infiltration in cancer of the larynx.

Author: Yilmaz T, Gedikoglu G, Celik A, Onerci M, and Turan E
Subjects: Adult, Aged, Carcinoma, Squamous Cell mortality, Carcinoma, Squamous Cell surgery, Cell Count, Humans, Laryngeal Neoplasms mortality, Laryngeal Neoplasms surgery, Lymphatic Metastasis, Male, Middle Aged, Neoplasm Recurrence, Local, Neoplasm Staging, Prognosis, Retrospective Studies, Survival Rate, Carcinoma, Squamous Cell pathology, Langerhans Cells physiology, Laryngeal Neoplasms pathology
Abstract: Objective: Determine the effect on prognosis of Langerhans cell infiltration in cancer of the larynx., Study Design and Setting: Retrospective review of 72 surgically treated patients with T1-3 lesions. The streptavidin-biotin method to determine Langerhans cell infiltration, which was graded as 1+, 2+, and 3+., Results: A higher degree of Langerhans cell infiltration was significantly associated with less cervical lymph node metastasis, longer disease-free survival, less locoregional recurrence, and less clinical N-positivity ( P < 0.05). According to multivariant analysis, Langerhans cell infiltration was independently related to disease-free survival and recurrence ( P < 0.05)., Conclusions: Langerhans cell infiltration is prognostically important in cancer of the larynx. More intense infiltration is significantly related to prolonged disease-free survival, less locoregional recurrence, less cervical lymph node metastasis, and less clinical N-positivity., Significance: Langerhans cell infiltration may be determined on a biopsy specimen and this information may be useful in deciding about elective neck dissection. Patients with mild infiltration may have a higher risk of locoregional recurrence, shorter disease-free survival, and therefore they suggest a poor prognosis.
Published: 2005
Full Text: View/download PDF

49. Consensus Conference on Nasal Polyposis.

Author: Passàli D, Bellussi L, Hassan HA, Mösges R, Bastaic L, Bernstein JM, Blum A, Gillet P, Brihaye P, Bunnag C, Caye-Thomasen P, Clement PA, Damiani V, Decroocq F, Dermentzopoulos M, Drügh S, Fabra JM, Goldschmidt O, Halpern GM, Harada T, Huizing EH, Jankowski R, Jareoncharsri P, Kalyoncu AF, Kane KJ, Karapantzos I, Keck T, Larsen K, Larsen P, Laspidis T, Lindemann J, Lopatin AS, Marchisio P, Mladina R, Muangsomboon S, Mygind N, Nonaka M, Onerci M, Onorato J, Ozu C, Passàli FM, Passàli GC, Pawankar R, Pigret D, Rettinger G, Sakakura Y, Simaskos N, Soetjipto D, Sperati G, Takizawa R, Tos M, Tunsuriyawong P, Yagi T, and Yamagishi S
Subjects: Administration, Intranasal, Adolescent, Adult, Age Distribution, Aged, Aged, 80 and over, Anti-Inflammatory Agents therapeutic use, Child, Child, Preschool, Eosinophils physiology, Female, History, 17th Century, History, Ancient, Humans, Incidence, Ion Transport physiology, Male, Mast Cells pathology, Middle Aged, Otolaryngology history, Prevalence, Quality of Life, Sex Distribution, Surgical Instruments history, Nasal Polyps drug therapy, Nasal Polyps epidemiology, Nasal Polyps history, Nasal Polyps pathology, Nasal Polyps surgery
Published: 2004

50. Dacryocystorhinostomy. Diagnosis and treatment of nasolacrimal canal obstructions.

Author: Onerci M
Subjects: Diagnostic Imaging, Humans, Intubation, Lacrimal Apparatus Diseases diagnosis, Lacrimal Apparatus Diseases surgery, Nasolacrimal Duct, Silicone Elastomers, Treatment Failure, Dacryocystorhinostomy, Lacrimal Duct Obstruction diagnosis
Abstract: Since Toti's original description of the dacryocystorhinostomy (CDR) in 1904, most surgery for relief of lacrimal obstruction has been performed through an external incision. Although the endonasal approach was for the first time introduced by Caldwell in 1893, its use stayed limited due to difficulties in visualizing the endonasal structures during the operation. The advance of the operating microscope and later a rigid endoscope into the surgery awakened interest for the endonasal approach. Endonasal DCR surgery has the advantages of preventing a scar on the skin and preserving the pump function of the naslacrimal sac. If the surgeon is experienced in endoscopic or microscopic surgery, correct localization of the window and addressing possible other nasal pathologies is possible in the same session. The endonasal laser DCR is not the first operation to be preferred due to the high cost, longer operation time, and less satisfactory results. It may be an alternative in cases with a tendency to bleeding. Endonasal surgery can not help canalicular problems. In these cases external surgery should be preferred. In revision cases, the endonasal approach is preferred by almost all authors. Even in external surgery, endoscopy may accompany the external approach to check the site of the fistula. Silicone intubation may be used routinely for two months to have better results, but no longer than 3 months to avoid complications. Silicone intubation is especially recommended in canalicular stenosis, small scarred lacrimal sacs and in reoperations. In this review article, diagnostic tests and various surgical methods, the advantages and disadvantages, were compared. Reasons for failure after surgery are also discussed.
Published: 2002

Catalog

Books, media, physical & digital resources

See catalog results

Searchworks

Select search scope, currently: Articles Catalog books, media & more in Jio Institute collections Articles journal articles & other e-resources

Search

Search Constraints

Refine your results

Search Limiters

Topic

Publication Year Range

Language

Publication Type

Journal

Region

Database

Publisher

125 results on '"Onerci, M."'

Search Results

Catalog

Select search scope, currently: Articles

Catalog

books, media & more in Jio Institute collections

Articles

journal articles & other e-resources