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Traces the history of the study of tumor viruses and its role in driving breakthroughs in cancer research.Worldwide, approximately one-fifth of human cancers are caused by tumor viruses, with hepatitis B virus and HPV being the leading culprits. While the explosive growth in molecular biology in the late twentieth century is well known, the role that the study of tumor viruses has played in driving many of the greatest breakthroughs is not. Without the insights gained by studying tumor viruses, many significant theoretical advancements over the last four decades in cellular and molecular biology would not have been made. More practically, the study of tumor viruses has saved thousands, if not millions, of lives.In Cancer Virus Hunters, Gregory J. Morgan traces the high points in the development of tumor virology, from Peyton Rous's pioneering work on chicken tumors in 1909 to the successful development of an HPV vaccine for cervical cancer in 2006. Morgan offers a novel approach to understanding the interconnectedness of a long series of biomedical breakthroughs, including those that led to seven Nobel prizes. Among other advances, Morgan describes and contextualizes the science that prompted the discoveries of reverse transcriptase, RNA splicing, the tumor suppressor p53, the vaccine for hepatitis B, and the HIV test. He also explores how'cancer virus hunters'have demonstrated the virtue of beginning with a simple system, even when investigating a complex disease like cancer.Based on extensive archival research and over fifty interviews with experts, Cancer Virus Hunters is a tour de force summarizing a century of research to show how discoveries made with tumor viruses came to dominate the contemporary understanding of cancer. By showcasing the scientists themselves, the book makes for an unusually accessible journey through the history of science. It will be of interest to biomedical professionals—especially in oncology, hepatology, and infectious disease—in addition to historians of science and anyone interested in cancer research.

CATCHING BREAST CANCER “How is it possible to catch breast cancer?” “How could breast cancer be an infectious disease?” For over 20 years James Lawson and his local and international colleagues have searched for the causes of breast cancer. By 2021 they had found the answers. From Australia, Italy, Austria and the US, a handful of medical scientists dared to think outside the accepted narrative. These outward-thinking individuals and small dedicated teams overcame the intense rivalry and competitiveness that so often stymies scientific progress. Over two decades, their collaborative work discovered that you can catch breast cancer and that it can be indeed an infectious disease. These groundbreaking findings have laid the groundwork for the most important step of all – preventing breast cancer. Lawson's work takes you behind these discoveries to the personal stories of those that have made such immense contributions to science and human health. The dry world of scientific papers and journals comes to life as one delves into the stories of those bright and brave minds that have driven this progress. Some humorous, others sad or poignant, all are fascinating. From Professor Generoso Bevilacqua of Pisa: “I have just completed reading your book. It was a fantastic experience! One can find everything in it. Science, history, personal memories and many humorous anecdotes.” Catching Breast Cancer is an important and compelling detective story for our current generation.