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Elderly and patients with comorbid conditions have higher risk of infection and complications. Vaccination hesitancy is defined as the refusal of vaccine or the delay in accepting it despite the availability of vaccines and vaccination services. This study was aimed at assessing knowledge, perception, and acceptability of healthcare staff towards different types of COVID-19 vaccination. A multicenter hospital-based descriptive cross-sectional study was implemented to study the knowledge, perception, and acceptability of healthcare staff towards COVID-19 vaccination. Multistage sampling technique was applied. Data were collected through a self-administered questionnaire filled by the participants. 400 participants were studied. 61% of the participants were females, and the most frequent age reported was between 18 and 35 years (67%). A statistically significant association (p=0.048) was found between knowledge about vaccination and professions. The most common vaccine type known and accepted was AstraZeneca vaccine. On assessing acceptability of COVID-19 vaccination, acceptance rate was high (63.8%) and 22.7% of the participants had already got vaccinated. The rejection rate among our staff was 27.4%. This study was conducted in April, 2021. Majority of our healthcare staff believed that vaccination is the key to combat the pandemic. One of the issues and concerns about vaccination was the safety and the risk of developing acute adverse events (p=0.001). Encouraging factor for vaccination was the fear of getting infection themselves and their families. The present study revealed the presence of good knowledge and acceptability among medical staff towards COVID-19 vaccinations in Sudan.

Objectives: In this prospective study we aim to demonstrate the effect of small doses of topical long acting insulin ( zink insulin ) application in wound healing. Methods: Thirty eight patients were studied in our private outpatient clinic between the years 2009 to 2011 , long acting insulin ( zinc insulin ) was used to avoid the hypoglycemic effect of insulin . Results: From a total of 38 patients, 20(52.6%) were males and 18(47.4%) were females. The median age was 49 years with a mean age of 35.11±11.543 years. There were different causes of the wounds, 21(55.3%) patients had previous operations leading to the wound, 9(23.7%) developed chronic wounds after burns, and 8(21.0%) had a wound due to trauma. The wounds were distributed in different sites of the body. In the trunk 24(63.2%) patients, in the extremeties 11(28.9%) patients and in the breast 3(7.9%). All the wounds were previously dressed with saline. The sizes of the wounds varied, minimum wound size was 1cm and maximum was 16cm with a mean of 6.32±4.319cm. 13(34.2%) of the wounds were infected, 18(47.4%) had allergy to stitches , 4(10.5%) had unhealthy granulation tissue and 3(7.9%) were covered with tough fibrin. These wounds were prepared prior to the study by giving antibiotic, removing the stitches, excising bad granulation tissue and removing fibrin. Soluble Insulin injection was prepared at a concentration of 1- Unit/10ml distilled water, then injected superficially in the inside of the wounds of the patient, and the effect was observed. The time range of saline-insulin treated wound closure was 15 days with a mean of 7.13±4.461 days. All patients had an excellent outcome and their wounds closed in a short time without any complications. Conclusion: Topical insulin application leads to acceleration of wound healing. The duration of wound healing and outcomes in our study were excellent. This depends on many factors also which should be taken seriously like wound infection of the wound and size. [ABSTRACT FROM AUTHOR]