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Schistosomiasis remains one of the severe ailments that affect both man and woman in South Africa. It is caused by blood fluke, and the rate at which it causes death is alarming in some areas of America, Asia as well as in African countries. It is a neglected tropical disease (NTD) with grave impact on social and economic situation of countries with low sanitation awareness. Thus, the search for lasting solution to this menace, has drawn the attention of many global researchers using phytochemicals from Scilla natalensis via in silico approach. The studied compounds were optimized using Spartan 14. Docking study was executed via Pymol, Autodock tool, Auto dock vina and discovery studio. Compound 9 with –8.2 kcal mol–1 and –9.4 kcal mol–1 as binding affinity proved to possess highest ability to inhibit glutathione S-transferase and thioredoxin-glutathione reductase than other compounds. Also, ADMET properties for compound 9 and praziquantel were explored and reported. Our findings may open the door for the design of novel drug-like molecules with better efficiency.

Plastic pollution is both a societal and environmental problem and citizen science has shown to be a useful tool to engage both the public and professionals in addressing it. However, knowledge on the educational and behavioral impacts of citizen science projects focusing on marine litter remains limited. Our preregistered study investigates the impact of the citizen science project Citizen Observation of Local Litter in coastal ECosysTems (COLLECT) on the participants’ ocean literacy, pro-environmental intentions and attitudes, well-being, and nature connectedness, using a pretest-posttest design. A total of 410 secondary school students from seven countries, in Africa (Benin, Cabo Verde, Côte d’Ivoire, Ghana, Morocco, Nigeria) and Asia (Malaysia) were trained to sample plastics on sandy beaches and to analyze their collection in the classroom. Non-parametric statistical tests (n = 239 matched participants) demonstrate that the COLLECT project positively impacted ocean literacy (i.e., awareness and knowledge of marine litter, self-reported litter-reducing behaviors, attitudes towards beach litter removal). The COLLECT project also led to higher pro-environmental behavioral intentions for students in Benin and Ghana (implying a positive spillover effect) and higher well-being and nature connectedness for students in Benin. Results are interpreted in consideration of a high baseline in awareness and attitudes towards marine litter, a low internal consistency of pro-environmental attitudes, the cultural context of the participating countries, and the unique settings of the project’s implementation. Our study highlights the benefits and challenges of understanding how citizen science impacts the perceptions and behaviors towards marine litter in youth from the respective regions.

The Citizen Observation of Local Litter in coastal ECosysTems (COLLECT) project (2021-2022) is a citizen science initiative, supported by the Partnership for Observation of the Global Ocean (POGO), which aimed to acquire distribution and abundance data of coastal plastic litter in seven countries: in Africa (Benin, Cabo Verde, Côte d’Ivoire, Ghana, Morocco, Nigeria) and Asia (Malaysia). In this paper, we describe the workflow used to establish and run this project, as well as the methodologies to acquire data. The COLLECT project consisted of training local students (15 - 18 years old) from ten second cycle institutions (“high schools”) on sampling and analyzing macro-, meso- and microplastics in beach sediments, using a quantitative assessment protocol. We further describe in detail the methodologies applied in assessing the impact of participating in the activities from a social sciences perspective. All documents and materials resulting from this project will be open access and available according to the FAIR Principles (Findable, Accessible, Interoperable, and Reusable). The results and outcomes from COLLECT will contribute to expanding knowledge and establishing baseline information on coastal plastic pollution, with citizen science being an enabler of open science, allowing data to be freely available to the public, academics and policymakers. Expected results from the use of the COLLECT protocol globally will further contribute to the identification of hotspots of coastal plastic litter, and bring awareness to local communities on the potential consequences of plastic pollution. The COLLECT project actively contributes with data suitable to survey plastic litter to the United Nations’ Sustainable Development Goals (UN SDGs), in particular to SDG 14, on the sustainable use of the ocean.