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4. Effect of Inhaled Xenon on Cardiac Function in Comatose Survivors of Out-of-Hospital Cardiac Arrest—A Substudy of the Xenon in Combination With Hypothermia After Cardiac Arrest Trial

Author

Saraste, Antti, Ballo, Haitham, Arola, Olli, Laitio, Ruut, Airaksinen, Juhani, Hynninen, Marja, Bäcklund, Minna, Ylikoski, Emmi, Wennervirta, Johanna, Pietilä, Mikko, Roine, Risto O, Harjola, Veli-Pekka, Niiranen, Jussi, Korpi, Kirsi, Varpula, Marjut, Scheinin, Harry, Maze, Mervyn, Vahlberg, Tero, Laitio, Timo, Virtanen, Sami, Parkkola, Riitta, Saunavaara, Jani, Martola, Juha, Silvennoinen, Heli, Tiainen, Marjaana, Grönlund, Juha, Inkinen, Outi, Silvasti, Päivi, Nukarinen, Eija, and Olkkola, Klaus T

Subjects
Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Clinical Sciences, Cardiovascular, Clinical Research, Heart Disease, Clinical Trials and Supportive Activities, cardiac arrest, cardiac function, cardioprotection, echocardiography, ejection fraction, myocardial strain, Clinical sciences
Abstract

This explorative substudy aimed at determining the effect of inhaled xenon on left ventricular function by echocardiography in comatose survivors of out-of-hospital cardiac arrest.DesignA randomized two-group single-blinded phase 2 clinical drug trial.SettingA multipurpose ICU in two university hospitals.PatientsOf the 110 randomized comatose survivors after out-of-hospital cardiac arrest with a shockable rhythm in the xenon in combination with hypothermia after cardiac arrest trial, 38 patients (24-76 yr old) with complete echocardiography were included in this study.InterventionsPatients were randomized to receive either inhaled xenon combined with hypothermia (33°C) for 24 hours or hypothermia treatment alone. Echocardiography was performed at hospital admission and 24 ± 4 hours after hypothermia.Measurements and main resultsLeft ventricular ejection fraction, myocardial longitudinal systolic strain, and diastolic function were analyzed blinded to treatment. There were 17 xenon and 21 control patients in whom echocardiography was completed. Clinical characteristics did not differ significantly between the groups. At admission, ejection fraction was similar in xenon and control patients (39% ± 10% vs 38% ± 11%; p = 0.711) but higher in xenon than control patients after hypothermia (50% ± 10% vs 42% ± 10%; p = 0.014). Global longitudinal systolic strain was similar in xenon and control patients at admission (-9.0% ± 3.8% vs -8.1% ± 3.6%; p = 0.555) but better in xenon than control patients after hypothermia (-14.4.0% ± 4.0% vs -10.5% ± 4.0%; p = 0.006). In patients with coronary artery disease, longitudinal strain improved in the nonischemic myocardial segments in xenon patients. There were no changes in diastolic function between the groups.ConclusionsAmong comatose survivors of a cardiac cause out-of-hospital cardiac arrest, inhaled xenon combined with hypothermia was associated with greater recovery of left ventricular systolic function in comparison with hypothermia alone.

Published
2021

5. Inhaled Xenon Attenuates Myocardial Damage in Comatose Survivors of Out-of-Hospital Cardiac Arrest The Xe-Hypotheca Trial

Author

Arola, Olli, Saraste, Antti, Laitio, Ruut, Airaksinen, Juhani, Hynninen, Marja, Bäcklund, Minna, Ylikoski, Emmi, Wennervirta, Johanna, Pietilä, Mikko, Roine, Risto O, Harjola, Veli-Pekka, Niiranen, Jussi, Korpi, Kirsi, Varpula, Marjut, Scheinin, Harry, Maze, Mervyn, Vahlberg, Tero, Laitio, Timo, Group, Xe-HYPOTHECA Study, Virtanen, Sami, Parkkola, Riitta, Saunavaara, Jani, Martola, Juha, Silvennoinen, Heli, Tiainen, Marjaana, Grönlund, Juha, Inkinen, Outi, Silvasti, Päivi, Nukarinen, Eija, and Olkkola, Klaus T

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Heart Disease, Clinical Research, Cardiovascular, Heart Disease - Coronary Heart Disease, Administration, Inhalation, Aged, Cardiopulmonary Resuscitation, Coma, Female, Finland, Heart, Hemodynamics, Humans, Hypothermia, Induced, Intensive Care Units, Male, Middle Aged, Myocardium, Out-of-Hospital Cardiac Arrest, Percutaneous Coronary Intervention, Treatment Outcome, Troponin T, Xenon, cardioprotection, hypothermia, out-of-hospital cardiac arrest, xenon, Xe-HYPOTHECA Study Group, Cardiorespiratory Medicine and Haematology, Public Health and Health Services, Cardiovascular System & Hematology, Cardiovascular medicine and haematology
Abstract

BACKGROUND:The authors previously reported that inhaled xenon combined with hypothermia attenuates brain white matter injury in comatose survivors of out-of-hospital cardiac arrest (OHCA). OBJECTIVES:A pre-defined secondary objective was to assess the effect of inhaled xenon on myocardial ischemic damage in the same study population. METHODS:A total of 110 comatose patients who had experienced OHCA from a cardiac cause were randomized to receive either inhaled xenon (40% end-tidal concentration) combined with hypothermia (33°C) for 24 h (n = 55; xenon group) or hypothermia treatment alone (n = 55; control group). Troponin-T levels were measured at hospital admission, and at 24 h, 48 h, and 72 h post-cardiac arrest. All available cases were analyzed for troponin-T release. RESULTS:Troponin-T measurements were available from 54 xenon patients and 54 control patients. The baseline characteristics did not differ significantly between the groups. After adjustments for age, sex, study site, primary coronary percutaneous intervention (PCI), and norepinephrine dose, the mean ± SD post-arrival incremental change of the ln-transformed troponin-T at 72 h was 0.79 ± 1.54 in the xenon group and 1.56 ± 1.38 in the control group (adjusted mean difference -0.66; 95% confidence interval: -1.16 to -0.16; p = 0.01). The effect of xenon on the change in the troponin-T values did not differ in patients with or without PCI or in those with a diagnosis of ST-segment elevation myocardial infarction (group by PCI or ST-segment elevation myocardial infarction interaction effect; p = 0.86 and p = 0.71, respectively). CONCLUSIONS:Among comatose survivors of OHCA, in comparison with hypothermia alone, inhaled xenon combined with hypothermia suggested a less severe myocardial injury as demonstrated by the significantly reduced release of troponin-T.

Published
2017

7. ESAIC focused guideline for the use of cardiac biomarkers in perioperative risk evaluation: Endorsement by the Scandinavian Society of Anaesthesiology and Intensive Care Medicine

Author

Rehn, Marius, Chew, Michelle, Kalliomaki, Maija, Olkkola, Klaus T., Sigurosson, Martin Ingi, Moller, Morten Hylander, Rehn, Marius, Chew, Michelle, Kalliomaki, Maija, Olkkola, Klaus T., Sigurosson, Martin Ingi, and Moller, Morten Hylander

Abstract

Background: The Clinical Practice Committee of the Scandinavian Society of Anaesthesiology and Intensive Care Medicine endorses the clinical practice guideline "ESAIC focused guideline for the use of cardiac biomarkers in perioperative risk evaluation." The guideline can provide guidance to Nordic anaesthesiologists on the perioperative use of cardiac biomarkers in patients undergoing non-cardiac surgery., Funding Agencies|Scandinavian Society of Anaesthesiology and Intensive Care Medicine and institutional and/or departmental sources

Published
2024
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8. Awake proning in patients with COVID-19-related hypoxemic acute respiratory failure:Endorsement by the Scandinavian Society of Anaesthesiology and Intensive Care Medicine

Author

Rehn, Marius, Chew, Michelle, Kalliomäki, Maija Liisa, Olkkola, Klaus T., Sigurðsson, Martin Ingi, Møller, Morten Hylander, Rehn, Marius, Chew, Michelle, Kalliomäki, Maija Liisa, Olkkola, Klaus T., Sigurðsson, Martin Ingi, and Møller, Morten Hylander

Abstract

Background Awake proning in spontaneously breathing patients with hypoxemic acute respiratory failure was applied during the coronavirus disease 2019 (COVID-19) pandemic to improve oxygenation while avoiding tracheal intubation. An updated systematic review and meta-analysis on the topic was published. Methods The Clinical practice committee (CPC) of the Scandinavian Society of Anaesthesiology and Intensive Care Medicine (SSAI) assessed the clinical practice guideline “Awake proning in patients with COVID-19-related hypoxemic acute respiratory failure: A rapid practice guideline” for possible endorsement. The Appraisal of Guidelines for REsearch and Evaluation (AGREE) II tool was used. Results Four out of six SSAI CPC members completed the appraisal. The individual domain totals were: Scope and Purpose 90%; Stakeholder Involvement 89%; Rigour of Development 74%; Clarity of Presentation 85%; Applicability 75%; Editorial Independence 98%; Overall Assessment 79%. Conclusion The SSAI CPC endorses the clinical practice guideline “Awake proning in patients with COVID-19-related hypoxemic acute respiratory failure: A rapid practice guideline”. This guideline serves as a useful decision aid for clinicians caring for critically ill patients with COVID-19-related acute hypoxemic respiratory failure and can be used to provide guidance on use of prone positioning in this group of patients., Background: Awake proning in spontaneously breathing patients with hypoxemic acute respiratory failure was applied during the coronavirus disease 2019 (COVID-19) pandemic to improve oxygenation while avoiding tracheal intubation. An updated systematic review and meta-analysis on the topic was published. Methods: The Clinical practice committee (CPC) of the Scandinavian Society of Anaesthesiology and Intensive Care Medicine (SSAI) assessed the clinical practice guideline “Awake proning in patients with COVID-19-related hypoxemic acute respiratory failure: A rapid practice guideline” for possible endorsement. The Appraisal of Guidelines for REsearch and Evaluation (AGREE) II tool was used. Results: Four out of six SSAI CPC members completed the appraisal. The individual domain totals were: Scope and Purpose 90%; Stakeholder Involvement 89%; Rigour of Development 74%; Clarity of Presentation 85%; Applicability 75%; Editorial Independence 98%; Overall Assessment 79%. Conclusion: The SSAI CPC endorses the clinical practice guideline “Awake proning in patients with COVID-19-related hypoxemic acute respiratory failure: A rapid practice guideline”. This guideline serves as a useful decision aid for clinicians caring for critically ill patients with COVID-19-related acute hypoxemic respiratory failure and can be used to provide guidance on use of prone positioning in this group of patients.

Published
2024

11. Effect of Inhaled Xenon on Cerebral White Matter Damage in Comatose Survivors of Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial

Author

Laitio, Ruut, Hynninen, Marja, Arola, Olli, Virtanen, Sami, Parkkola, Riitta, Saunavaara, Jani, Roine, Risto O, Grönlund, Juha, Ylikoski, Emmi, Wennervirta, Johanna, Bäcklund, Minna, Silvasti, Päivi, Nukarinen, Eija, Tiainen, Marjaana, Saraste, Antti, Pietilä, Mikko, Airaksinen, Juhani, Valanne, Leena, Martola, Juha, Silvennoinen, Heli, Scheinin, Harry, Harjola, Veli-Pekka, Niiranen, Jussi, Korpi, Kirsi, Varpula, Marjut, Inkinen, Outi, Olkkola, Klaus T, Maze, Mervyn, Vahlberg, Tero, and Laitio, Timo

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Health Sciences, Clinical Trials and Supportive Activities, Neurosciences, Rehabilitation, Clinical Research, Cardiovascular, Biomedical Imaging, Brain Disorders, Good Health and Well Being, Administration, Inhalation, Adult, Aged, Anisotropy, Cardiopulmonary Resuscitation, Coma, Diffusion Magnetic Resonance Imaging, Female, Finland, Humans, Hypothermia, Induced, Male, Middle Aged, Out-of-Hospital Cardiac Arrest, Single-Blind Method, Statistics, Nonparametric, Survival Analysis, Survivors, Time Factors, Treatment Outcome, White Matter, Xenon, Medical and Health Sciences, General & Internal Medicine, Biomedical and clinical sciences, Health sciences
Abstract

ImportanceEvidence from preclinical models indicates that xenon gas can prevent the development of cerebral damage after acute global hypoxic-ischemic brain injury but, thus far, these putative neuroprotective properties have not been reported in human studies.ObjectiveTo determine the effect of inhaled xenon on ischemic white matter damage assessed with magnetic resonance imaging (MRI).Design, setting, and participantsA randomized single-blind phase 2 clinical drug trial conducted between August 2009 and March 2015 at 2 multipurpose intensive care units in Finland. One hundred ten comatose patients (aged 24-76 years) who had experienced out-of-hospital cardiac arrest were randomized.InterventionsPatients were randomly assigned to receive either inhaled xenon combined with hypothermia (33°C) for 24 hours (n = 55 in the xenon group) or hypothermia treatment alone (n = 55 in the control group).Main outcomes and measuresThe primary end point was cerebral white matter damage as evaluated by fractional anisotropy from diffusion tensor MRI scheduled to be performed between 36 and 52 hours after cardiac arrest. Secondary end points included neurological outcome assessed using the modified Rankin Scale (score 0 [no symptoms] through 6 [death]) and mortality at 6 months.ResultsAmong the 110 randomized patients (mean age, 61.5 years; 80 men [72.7%]), all completed the study. There were MRI data from 97 patients (88.2%) a median of 53 hours (interquartile range [IQR], 47-64 hours) after cardiac arrest. The mean global fractional anisotropy values were 0.433 (SD, 0.028) in the xenon group and 0.419 (SD, 0.033) in the control group. The age-, sex-, and site-adjusted mean global fractional anisotropy value was 3.8% higher (95% CI, 1.1%-6.4%) in the xenon group (adjusted mean difference, 0.016 [95% CI, 0.005-0.027], P = .006). At 6 months, 75 patients (68.2%) were alive. Secondary end points at 6 months did not reveal statistically significant differences between the groups. In ordinal analysis of the modified Rankin Scale, the median (IQR) value was 1 (1-6) in the xenon group and 1 (0-6) in the control group (median difference, 0 [95% CI, 0-0]; P = .68). The 6-month mortality rate was 27.3% (15/55) in the xenon group and 34.5% (19/55) in the control group (adjusted hazard ratio, 0.49 [95% CI, 0.23-1.01]; P = .053).Conclusions and relevanceAmong comatose survivors of out-of-hospital cardiac arrest, inhaled xenon combined with hypothermia compared with hypothermia alone resulted in less white matter damage as measured by fractional anisotropy of diffusion tensor MRI. However, there was no statistically significant difference in neurological outcomes or mortality at 6 months. These preliminary findings require further evaluation in an adequately powered clinical trial designed to assess clinical outcomes associated with inhaled xenon among survivors of out-of-hospital cardiac arrest.Trial registrationclinicaltrials.gov Identifier: NCT00879892.

Published
2016

16. Ketamine Pharmacokinetics: A Systematic Review of the Literature, Meta-analysis, and Population Analysis

Author

Kamp, Jasper, Olofsen, Erik, Henthorn, Thomas K., van Velzen, Monique, Niesters, Marieke, Dahan, Albert, Backman, Janne T., Drover, David R., Elkomy, Mohammed H., Fanta, Samuel, Flint, Robert B., Gustafsson, Lars L., Hammer, Gregory B., Herd, David W., Kalso, Eija, Mathôt, Ron A.A., Olkkola, Klaus, Peltoniemi, Marko, Persson, Jan, Ramamoorthy, Chandra, Saari, Teijo I., and Sherwin, Catherine M.T.

Published
2020
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22. ISTH guidelines for antithrombotic treatment in COVID-19: Endorsement by the Scandinavian Society of Anaesthesiology and Intensive Care Medicine

Author

Chew, Michelle, Olkkola, Klaus T., Kalliomaki, Maija-Liisa, Rehn, Marius, Sigurdsson, Martin Ingi, Moller, Morten Hylander, Chew, Michelle, Olkkola, Klaus T., Kalliomaki, Maija-Liisa, Rehn, Marius, Sigurdsson, Martin Ingi, and Moller, Morten Hylander

Abstract

The Clinical Practice Committee of the Scandinavian Society of Anaesthesiology and Intensive Care Medicine endorses the ISTH guidelines for antithrombotic treatment in COVID-19. This evidence-based guideline serves as a useful decision aid for Nordic anaesthesiologists caring for patients with COVID-19., Funding Agencies|Scandinavian Society of Anaesthesiology and Intensive Care Medicine

Published
2023
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23. Saudi Critical Care Society clinical practice guidelines on the prevention of venous thromboembolism in adults with trauma: Endorsement by the Scandinavian Society of Anaesthesiology and Intensive Care Medicine

Author

Sigurosson, Martin Ingi, Chew, Michelle, Olkkola, Klaus T., Rehn, Marius, Kalliomaki, Maija-Liisa, Moller, Morten Hylander, Sigurosson, Martin Ingi, Chew, Michelle, Olkkola, Klaus T., Rehn, Marius, Kalliomaki, Maija-Liisa, and Moller, Morten Hylander

Abstract

The Clinical Practice Committee of the Scandinavian Society of Anaesthesiology and Intensive Care Medicine endorses the clinical practice guideline Saudi Critical Care Society clinical practice guidelines on the prevention of venous thromboembolism in adults with trauma: reviewed for evidence-based integrity and endorsed by the Scandinavian Society of Anaesthesiology and Intensive Care Medicine. This clinical practice guideline serves as a useful decision aid for Nordic anaesthesiologists managing adult trauma patients in the operating room and in the intensive care unit., Funding Agencies|Scandinavian Society of Anaesthesiology and Intensive Care Medicine

Published
2023
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24. ISTH guidelines for antithrombotic treatment in COVID-19:Endorsement by the Scandinavian Society of Anaesthesiology and Intensive Care Medicine

Author

Chew, Michelle S., Olkkola, Klaus T., Kalliomäki, Maija Liisa, Rehn, Marius, Sigurðsson, Martin Ingi, Møller, Morten Hylander, Chew, Michelle S., Olkkola, Klaus T., Kalliomäki, Maija Liisa, Rehn, Marius, Sigurðsson, Martin Ingi, and Møller, Morten Hylander

Abstract

The Clinical Practice Committee of the Scandinavian Society of Anaesthesiology and Intensive Care Medicine endorses the ISTH guidelines for antithrombotic treatment in COVID-19. This evidence-based guideline serves as a useful decision aid for Nordic anaesthesiologists caring for patients with COVID-19.

Published
2023

25. Awake proning in patients with COVID-19-related hypoxemic acute respiratory failure: Endorsement by the Scandinavian Society of Anaesthesiology and Intensive Care Medicine

Author

Rehn, Marius, Chew, Michelle, Kalliomaki, Maija-Liisa, Olkkola, Klaus T., Sigurdsson, Martin Ingi, Moller, Morten Hylander, Rehn, Marius, Chew, Michelle, Kalliomaki, Maija-Liisa, Olkkola, Klaus T., Sigurdsson, Martin Ingi, and Moller, Morten Hylander

Abstract

Background: Awake proning in spontaneously breathing patients with hypoxemic acute respiratory failure was applied during the coronavirus disease 2019 (COVID-19) pandemic to improve oxygenation while avoiding tracheal intubation. An updated systematic review and meta-analysis on the topic was published.Methods: The Clinical practice committee (CPC) of the Scandinavian Society of Anaesthesiology and Intensive Care Medicine (SSAI) assessed the clinical practice guideline "Awake proning in patients with COVID-19-related hypoxemic acute respiratory failure: A rapid practice guideline" for possible endorsement. The Appraisal of Guidelines for REsearch and Evaluation (AGREE) II tool was used.Results: Four out of six SSAI CPC members completed the appraisal. The individual domain totals were: Scope and Purpose 90%; Stakeholder Involvement 89%; Rigour of Development 74%; Clarity of Presentation 85%; Applicability 75%; Editorial Independence 98%; Overall Assessment 79%.Conclusion: The SSAI CPC endorses the clinical practice guideline "Awake proning in patients with COVID-19-related hypoxemic acute respiratory failure: A rapid practice guideline". This guideline serves as a useful decision aid for clinicians caring for critically ill patients with COVID-19-related acute hypoxemic respiratory failure and can be used to provide guidance on use of prone positioning in this group of patients., Funding Agencies|Scandinavian Society of Anaesthesiology and Intensive Care Medicine

Published
2023
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26. Saudi Critical Care Society clinical practice guidelines on the prevention of venous thromboembolism in adults with trauma:Endorsement by the Scandinavian Society of Anaesthesiology and Intensive Care Medicine

Author

Sigurðsson, Martin Ingi, Chew, Michelle, Olkkola, Klaus T., Rehn, Marius, Kalliomäki, Maija Liisa, Møller, Morten Hylander, Sigurðsson, Martin Ingi, Chew, Michelle, Olkkola, Klaus T., Rehn, Marius, Kalliomäki, Maija Liisa, and Møller, Morten Hylander

Abstract

The Clinical Practice Committee of the Scandinavian Society of Anaesthesiology and Intensive Care Medicine endorses the clinical practice guideline Saudi Critical Care Society clinical practice guidelines on the prevention of venous thromboembolism in adults with trauma: reviewed for evidence-based integrity and endorsed by the Scandinavian Society of Anaesthesiology and Intensive Care Medicine. This clinical practice guideline serves as a useful decision aid for Nordic anaesthesiologists managing adult trauma patients in the operating room and in the intensive care unit.

Published
2023

28. Awake proning in patients with COVID‐19‐related hypoxemic acute respiratory failure: Endorsement by the Scandinavian Society of Anaesthesiology and Intensive Care Medicine.

Author

Rehn, Marius, Chew, Michelle, Kalliomäki, Maija‐Liisa, Olkkola, Klaus T., Sigurðsson, Martin Ingi, and Møller, Morten Hylander

Subjects
ADULT respiratory distress syndrome, HYPOXEMIA, CRITICAL care medicine, CRITICALLY ill patient care, COVID-19
Abstract

Background: Awake proning in spontaneously breathing patients with hypoxemic acute respiratory failure was applied during the coronavirus disease 2019 (COVID‐19) pandemic to improve oxygenation while avoiding tracheal intubation. An updated systematic review and meta‐analysis on the topic was published. Methods: The Clinical practice committee (CPC) of the Scandinavian Society of Anaesthesiology and Intensive Care Medicine (SSAI) assessed the clinical practice guideline "Awake proning in patients with COVID‐19‐related hypoxemic acute respiratory failure: A rapid practice guideline" for possible endorsement. The Appraisal of Guidelines for REsearch and Evaluation (AGREE) II tool was used. Results: Four out of six SSAI CPC members completed the appraisal. The individual domain totals were: Scope and Purpose 90%; Stakeholder Involvement 89%; Rigour of Development 74%; Clarity of Presentation 85%; Applicability 75%; Editorial Independence 98%; Overall Assessment 79%. Conclusion: The SSAI CPC endorses the clinical practice guideline "Awake proning in patients with COVID‐19‐related hypoxemic acute respiratory failure: A rapid practice guideline". This guideline serves as a useful decision aid for clinicians caring for critically ill patients with COVID‐19‐related acute hypoxemic respiratory failure and can be used to provide guidance on use of prone positioning in this group of patients. [ABSTRACT FROM AUTHOR]

Published
2024
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35. Transfusion strategies in bleeding critically ill adults : A clinical practice guideline from the European Society of Intensive Care Medicine: Endorsement by the Scandinavian Society of Anaesthesiology and Intensive Care Medicine

Author

Moller, Morten Hylander, Sigurosson, Martin Ingi, Olkkola, Klaus T., Rehn, Marius, Yli-Hankala, Arvi, Chew, Michelle S., HUS Perioperative, Intensive Care and Pain Medicine, Department of Diagnostics and Therapeutics, Clinicum, and Anestesiologian yksikkö

Subjects
critically ill, ICU, AGREE II, bleeding, 3126 Surgery, anesthesiology, intensive care, radiology, clinical practice guideline, transfusion
Abstract

The Clinical Practice Committee of the Scandinavian Society of Anaesthesiology and Intensive Care Medicine endorses the clinical practice guideline Transfusion strategies in bleeding critically ill adults: a clinical practice guideline from the European Society of Intensive Care Medicine. This trustworthy clinical practice guideline serves as a useful decision aid for Nordic anaesthesiologists caring for critically ill patients with bleeding. Non

Published
2022

36. Surviving sepsis campaign : International guidelines for management of sepsis and septic shock in adults 2021-endorsement by the Scandinavian society of anaesthesiology and intensive care medicine

Author

Rehn, Marius, Chew, Michelle S., Olkkola, Klaus T., Sigurdsson, Martin Ingi, Yli-Hankala, Arvi, Moller, Morten Hylander, HUS Perioperative, Intensive Care and Pain Medicine, Department of Diagnostics and Therapeutics, Clinicum, and Anestesiologian yksikkö

Subjects
sepsis, adults, septic shock, AGREE II, 3126 Surgery, anesthesiology, intensive care, radiology, clinical practice guideline
Abstract

The Clinical Practice Committee of the Scandinavian Society of Anaesthesiology and Intensive Care Medicine endorses the clinical practice guideline Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021. The guideline serves as a useful bedside decision aid for clinicians managing adults with suspected and confirmed septic shock and sepsis-associated organ dysfunction. Non

Published
2022

40. Transfusion strategies in bleeding critically ill adults : A clinical practice guideline from the European Society of Intensive Care Medicine: Endorsement by the Scandinavian Society of Anaesthesiology and Intensive Care Medicine

Author

Hylander Moller, Morten, Sigurosson, Martin Ingi, Olkkola, Klaus T., Rehn, Marius, Yli-Hankala, Arvi, Chew, Michelle, Hylander Moller, Morten, Sigurosson, Martin Ingi, Olkkola, Klaus T., Rehn, Marius, Yli-Hankala, Arvi, and Chew, Michelle

Abstract

The Clinical Practice Committee of the Scandinavian Society of Anaesthesiology and Intensive Care Medicine endorses the clinical practice guideline Transfusion strategies in bleeding critically ill adults: a clinical practice guideline from the European Society of Intensive Care Medicine. This trustworthy clinical practice guideline serves as a useful decision aid for Nordic anaesthesiologists caring for critically ill patients with bleeding., Funding Agencies|Scandinavian Society of Anaesthesiology and Intensive Care Medicine

Published
2022
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41. Therapeutics and COVID-19 - A living WHO guideline : Endorsement by the Scandinavian Society of Anaesthesiology and Intensive Care Medicine

Author

Moller, Morten H., Chew, Michelle, Olkkola, Klaus T., Rehn, Marius, Yli-Hankala, Arvi, Sigurdsson, Martin I, Moller, Morten H., Chew, Michelle, Olkkola, Klaus T., Rehn, Marius, Yli-Hankala, Arvi, and Sigurdsson, Martin I

Abstract

The Clinical Practice Committee of the Scandinavian Society of Anaesthesiology and Intensive Care Medicine endorses the Living WHO guideline on therapeutics and COVID-19. This trustworthy continuously updated guideline serves as a highly useful decision aid for Nordic anaesthesiologists caring for patients with COVID-19., Funding Agencies|Scandinavian Society of Anaesthesiology and Intensive Care Medicine

Published
2022
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42. A policy for diversity, equity, inclusion and anti-racism in the Scandinavian Society of Anaesthesiology and Intensive Care Medicine (SSAI)

Author

Laake, Jon H., Astvad, Mads, Bentsen, Gunnar, Escher, Cecilia, Haney, Michael, Hoffmann-Petersen, Joachim, Hyllested, Mette, Junttila, Eija, Møller, Morten H., Nellgård, Per, Nyberg, Annette, Olkkola, Klaus, Pedersen, Steffen K. A., Pischke, Søren E., Reinikainen, Matti, Strand, Kristian, Thorarensen, Gunnar, Thormar, Katrin, Tønnessen, Tor I., Laake, Jon H., Astvad, Mads, Bentsen, Gunnar, Escher, Cecilia, Haney, Michael, Hoffmann-Petersen, Joachim, Hyllested, Mette, Junttila, Eija, Møller, Morten H., Nellgård, Per, Nyberg, Annette, Olkkola, Klaus, Pedersen, Steffen K. A., Pischke, Søren E., Reinikainen, Matti, Strand, Kristian, Thorarensen, Gunnar, Thormar, Katrin, and Tønnessen, Tor I.

Published
2022
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43. Surviving sepsis campaign:International guidelines for management of sepsis and septic shock in adults 2021 - endorsement by the Scandinavian society of anaesthesiology and intensive care medicine

Author

Rehn, Marius, Chew, Michelle S., Olkkola, Klaus T., Ingi Sigurðsson, Martin, Yli-Hankala, Arvi, Hylander Møller, Morten, Rehn, Marius, Chew, Michelle S., Olkkola, Klaus T., Ingi Sigurðsson, Martin, Yli-Hankala, Arvi, and Hylander Møller, Morten

Abstract

The Clinical Practice Committee of the Scandinavian Society of Anaesthesiology and Intensive Care Medicine endorses the clinical practice guideline Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021. The guideline serves as a useful bedside decision aid for clinicians managing adults with suspected and confirmed septic shock and sepsis-associated organ dysfunction.

Published
2022

44. Regional anaesthesia in patients on antithrombotic drugs – a joint ESAIC/ESRA guideline:Endorsement by the Scandinavian Society of Anaesthesiology and Intensive Care Medicine

Author

Møller, Morten Hylander, Sigurðsson, Martin Ingi, Olkkola, Klaus T., Rehn, Marius, Yli-Hankala, Arvi, Chew, Michelle S., Møller, Morten Hylander, Sigurðsson, Martin Ingi, Olkkola, Klaus T., Rehn, Marius, Yli-Hankala, Arvi, and Chew, Michelle S.

Abstract

The Clinical Practice Committee of the Scandinavian Society of Anaesthesiology and Intensive Care Medicine endorses the clinical practice guideline Regional anaesthesia in patients on antithrombotic drugs – a joint ESAIC/ESRA guideline. This clinical practice guideline serves as a useful decision aid for Nordic anaesthesiologists providing regional anaesthesia to adult patients on antithrombotic drugs.

Published
2022

45. Transfusion strategies in bleeding critically ill adults:A clinical practice guideline from the European Society of Intensive Care Medicine: Endorsement by the Scandinavian Society of Anaesthesiology and Intensive Care Medicine

Author

Møller, Morten Hylander, Sigurðsson, Martin Ingi, Olkkola, Klaus T., Rehn, Marius, Yli-Hankala, Arvi, Chew, Michelle S., Møller, Morten Hylander, Sigurðsson, Martin Ingi, Olkkola, Klaus T., Rehn, Marius, Yli-Hankala, Arvi, and Chew, Michelle S.

Abstract

The Clinical Practice Committee of the Scandinavian Society of Anaesthesiology and Intensive Care Medicine endorses the clinical practice guideline Transfusion strategies in bleeding critically ill adults: a clinical practice guideline from the European Society of Intensive Care Medicine. This trustworthy clinical practice guideline serves as a useful decision aid for Nordic anaesthesiologists caring for critically ill patients with bleeding.

Published
2022

46. Therapeutics and COVID-19 - A living WHO guideline:Endorsement by the Scandinavian Society of Anaesthesiology and Intensive Care Medicine

Author

Møller, Morten H., Chew, Michelle S., Olkkola, Klaus T., Rehn, Marius, Yli-Hankala, Arvi, Sigurðsson, Martin I., Møller, Morten H., Chew, Michelle S., Olkkola, Klaus T., Rehn, Marius, Yli-Hankala, Arvi, and Sigurðsson, Martin I.

Abstract

The Clinical Practice Committee of the Scandinavian Society of Anaesthesiology and Intensive Care Medicine endorses the Living WHO guideline on therapeutics and COVID-19. This trustworthy continuously updated guideline serves as a highly useful decision aid for Nordic anaesthesiologists caring for patients with COVID-19.

Published
2022

47. Regional anaesthesia in patients on antithrombotic drugs - a joint ESAIC/ESRA guideline: Endorsement by the Scandinavian Society of Anaesthesiology and Intensive Care Medicine

Author

Møller, Morten Hylander, Sigurðsson, Martin Ingi, Olkkola, Klaus T., Rehn, Marius, Yli-Hankala, Arvi, Chew, Michelle S, Møller, Morten Hylander, Sigurðsson, Martin Ingi, Olkkola, Klaus T., Rehn, Marius, Yli-Hankala, Arvi, and Chew, Michelle S

Abstract

The Clinical Practice Committee of the Scandinavian Society of Anaesthesiology and Intensive Care Medicine endorses the clinical practice guideline Regional anaesthesia in patients on antithrombotic drugs - a joint ESAIC/ESRA guideline. This clinical practice guideline serves as a useful decision aid for Nordic anaesthesiologists providing regional anaesthesia to adult patients on antithrombotic drugs., Funding Agencies|Scandinavian Society of Anaesthesiology and Intensive Care Medicine

Published
2022
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