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The author has conducted a study of the influence of the dietary supplement (DS) Antihot® on the parameters of working capacity in athletes specializing in Kyokushin karate. Twenty athletes of both genders, who were qualified as Candidates for Master of Sports and upward frating of Candidate for Master of Sports provides practicing this sports event for at least five years and winning prize places at Ukraine's championships), participated in the experiment by 10 persons in the control and experimental groups, respectively. The athletes from the experimental group were taking DS Antihot® under the following regimen: 3 days - oral intake, 3 days interval, in the whole - 4 cycles of DS Antihot® administration. At that, the athletes were taking the paraphannaceutical in doses of one capsule 3 times a day after meals (it amounts to 0.6 g of bemithylum as an active substance of DS Antihot® per day), and during the following cycles - one capsule 2 times a day after meals (0.4 g of bemithylum per day). The athletes from the control group were taking a placebo under the same regimen, respectively. To evaluate the level of physical and technical preparedness of the tested athletes, the following pedagogical tests were applied: a 60-meter run - for assessment of speed qualities; a 3000-meter run - for evaluation of endurance; pulls-up - for evaluation of strength abilities; calculation of tethnically correct kicks made against the special-purpose apparatus "Makiwara" (jodan mawashi geri - circular kick against the upper section) per one minute (Makiwara test) - for evaluation of technical preparedness. The estimation of DS Antihot® tolerance was made employing a subjective appraisal of the athletes' health status, electrocardiography monitoring, complete and biochemical blood counts and total urine tests. It was determined that DS Antihot® administration during the preparatory period according to the described scheme promoted the boost of general endurance in athletes specializing in Kyokushin karate, but did not exhibit an effect upon speed qualities, strength parameters (strength endurance) and the indices of technical qualification. In the mean time, the investigated paraphannaceutical is well tolerated by the athletes, which can be suggested due to the absence of health status complaints, lack of pathological electrocardiograph changes, findings of complete and biochemical blood counts and total urine tests in the athletes from the experimental group. The obtained data allow considering the administration of this parapharmaceutical to be expedient in the practical training of top-class athletes specializing in combat contact sports. [ABSTRACT FROM AUTHOR]

Dietary supplement Antihot® was tested as a potential means for increasing human working capacity in a high altitude environment. During three days the volunteers (athletes specializing in mountaineering) climbed to the height of 3,700 m above sea level by marches of 15 km each with a load of 35-40 kg. Twenty nine young men aged 20-35 years old participated in the trip, and 15 of them were taking Antihot® in capsules, 1 capsule (0.5 g) three times a day during a meal, for 4 days. The other 13 men, who were included in the control group, were taking a placebo under a similar routine. Besides hypoxic hypoxia the ascent was complicated by the night temperature fall to -5 °C, preventing the climbers from having rest and recreation. It was registered that with taking Antihot® the climbing was easier to tolerate. The number of complaints recorded in a mountain experience questionnaire decreased, and, above all, the course of halt recreation had run much quicker. In the upland environment, the improvement of a feeling of health was recorded, physical loads got easier to overcome, and fatigue was lowered. A distinct decrease of hypoxic hypoxia was registered. Symptomatology relevant to the presentations of acute mountain pathology developed to a minor ratio and virtually did not affect on the volunteers' functional condition and their marking capacity. In comparison to the control group the average number of complaints decreased to 4 times less, including cerebral and common complaints which decreased by 6 times less, cardiorespiratory ones - to 2.5 times less, and digestive and excretory complaints - 20 times less. These results are sure to argue for distinct antihypoxic action by Antihot®. Heart rate is a general parameter of physiological function tension. At the post-ascent examination of the climbers who had taken Antihot®, it remained lower than background meaning both at rest and while conducting a loading test by 5.5 and 11.4%, respectively. In aggregate with a reliable increase of breath-holding (Stange test) by 25.5% against taking Antihot®, results argue for a favorable preparation impact on the functions of the oxygen transportation system, rapid and complete removal of oxygen debt and, maybe, as a whole, for a decrease of tension level in the body's physiological systems, thus, facilitating adaptation and working capacity in a high altitude environment. Therefore, Antihot® has displayed high efficacy in increasing tolerance to unfavorable factors of environment in high altitude as well as in facilitating tolerance to physical loading and maintaining a feeling of well-being during the whole stay in the mountains. [ABSTRACT FROM AUTHOR]