27 results on '"Olieman J"'
Search Results
2. Ketogenic diet for epilepsy and obesity:Is it the same?
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Tagliabue, A., Armeno, M., Berk, K. A., Guglielmetti, M., Ferraris, C., Olieman, J., van der Louw, E., Tagliabue, A., Armeno, M., Berk, K. A., Guglielmetti, M., Ferraris, C., Olieman, J., and van der Louw, E.
- Abstract
The term “ketogenic diet” (KD) is used for a wide variety of diets with diverse indications ranging from obesity to neurological diseases, as if it was the same diet. This terminology is confusing for patients and the medical and scientific community. The term “ketogenic” diet implies a dietary regimen characterized by increased levels of circulating ketone bodies that should be measured in blood (beta-hydroxybutyrate), urine (acetoacetate) or breath (acetone) to verify the “ketogenic metabolic condition”. Our viewpoint highlights that KDs used for epilepsy and obesity are not the same; the protocols aimed at weight loss characterized by low-fat, low-CHO and moderate/high protein content are not ketogenic by themselves but may become mildly ketogenic when high calorie restriction is applied. In contrast, there are standardized protocols for neurological diseases treatment for which ketosis has been established to be part of the mechanism of action. Therefore, in our opinion, the term ketogenic dietary therapy (KDT) should be reserved to the protocols considered for epilepsy and other neurological diseases, as suggested by the International Study Group in 2018. We propose to adjust the abbreviations in VLCHKD for Very Low CarboHydrate Ketogenic Diet and VLEKD for Very Low Energy Ketogenic Diet, to clarify the differences in dietary composition. We recommend that investigators describe the researchers describing efficacy or side effects of KDs, to clearly specify the dietary protocol used with its unique acronym and level of ketosis, when ketosis is considered as a component of the diet's mechanism of action.
- Published
- 2024
3. Nutritional Requirements And Inflammation In Critically Ill Pregnant Covid-19 Patients
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Van Der Hoven, B., primary, Lakenman, P., additional, Olieman, J., additional, Joosten, K., additional, and Bakker, J., additional
- Published
- 2023
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4. Body composition and functional status tools for nutritional assessment of hospitalized adults: a systematic review
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Berk, K., primary, Smith, L., additional, Olieman, J., additional, Ligthart-Melis, G., additional, and Earthman, C., additional
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- 2023
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5. Body composition in relation with tailored nutritional support and clinical outcome in critically ill COVID-19 patients
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Lakenman, P., primary, van Marwijk, I., additional, van der Hoven, B., additional, van Bommel, J., additional, Olieman, J., additional, and Joosten, K., additional
- Published
- 2023
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6. Neonatal short bowel syndrome as a model of intestinal failure: Physiological background for enteral feeding
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Goulet, O., Olieman, J., Ksiazyk, J., Spolidoro, J., Tibboe, D., Köhler, H., Yagci, R. Vural, Falconer, J., Grimble, G., and Beattie, R.M.
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- 2013
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7. The usefulness of a new indirect calorimeter in critically ill adult patients and its impact on nutritional therapy
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Lakenman, P., van der Hoven, B., van Bommel, J., Olieman, J., and Joosten, K.
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- 2024
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8. Energy expenditure and feeding practices and tolerance during the acute and late phase of critically ill COVID-19 patients
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Lakenman, P. L.M., van der Hoven, B., Schuijs, J. M., Eveleens, R. D., van Bommel, J., Olieman, J. F., Joosten, K. F.M., Lakenman, P. L.M., van der Hoven, B., Schuijs, J. M., Eveleens, R. D., van Bommel, J., Olieman, J. F., and Joosten, K. F.M.
- Abstract
Background & aims: Different metabolic phases can be distinguished in critical illness, which influences nutritional treatment. Achieving optimal nutritional treatment during these phases in critically ill patients is challenging. COVID-19 patients seem particularly difficult to feed due to gastrointestinal problems. Our aim was to describe measured resting energy expenditure (mREE) and feeding practices and tolerance during the acute and late phases of critical illness in COVID-19 patients. Methods: Observational study including critically ill mechanically ventilated adult COVID-19 patients. Indirect calorimetry (Q-NRG+, Cosmed) was used to determine mREE during the acute (day 0–7) and late phase (>day 7) of critical illness. Data on nutritional intake, feeding tolerance and urinary nitrogen loss were collected simultaneously. A paired sample t-test was performed for mREE in both phases. Results: We enrolled 21 patients with a median age of 59 years [44–66], 67% male and median BMI of 31.5 kg/m2 [25.7–37.8]. Patients were predominantly fed with EN in both phases. No significant difference in mREE was observed between phases (p = 0.529). Sixty-five percent of the patients were hypermetabolic in both phases. Median delivery of energy as percentage of mREE was higher in the late phase (94%) compared to the acute phase (70%) (p = 0.001). Urinary nitrogen losses were significant higher in the late phase (p = 0.003). Conclusion: In both the acute and late phase, the majority of the patients were hypermetabolic and fed enterally. In the acute phase patients were fed hypocaloric whereas in the late phase this was almost normocaloric, conform ESPEN guidelines. No significant difference in mREE was observed between phases. Hypermetabolism in both phases in conjunction with an increasing loss of urinary nitrogen may indicate that COVID-19 patients remain in a prolonged acute, catabolic phase.
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- 2021
9. Voeding bij het kortedarmsyndroom
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Olieman, J. F. and Dijkstra, T.
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- 2006
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10. *O-31: Growth and Fat Mass, But Not Fat-free Mass, are Compromised in Infants with Parenteral Nutrition Need after Neonatal Intestinal Surgery
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J. Roelants, Olieman J, Jonathan C. K. Wells, Hulst J, Marijn J. Vermeulen, Kastelijn W, Vlug L, Rings E, Rene M. H. Wijnen, Neelis E, Dimitris Rizopoulos, de Koning B, and Mary Fewtrell
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Intestinal surgery ,Transplantation ,medicine.medical_specialty ,Parenteral nutrition ,business.industry ,Fat free mass ,Internal medicine ,Medicine ,business ,Gastroenterology ,Fat mass - Published
- 2021
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11. Optimal clinical management of children receiving ketogenic parenteral nutrition: a clinical practice guide
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van der Louw, Elles, Aldaz, V, Harvey, J, Roan, M, van den Hurk, D, Cross, JH, Auvin, S, Forbes, E, van de Bor, B, Olieman, J, Simchowitz, V, Storme, T, Klepper, J, Dressler, A, van der Louw, Elles, Aldaz, V, Harvey, J, Roan, M, van den Hurk, D, Cross, JH, Auvin, S, Forbes, E, van de Bor, B, Olieman, J, Simchowitz, V, Storme, T, Klepper, J, and Dressler, A
- Published
- 2020
12. OR26: National Obligatory Screening Lead to Decreased Malnutrition Rates in Paediatric Inpatients
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van den Berg, A., primary, Brinksma, A., additional, Olieman, J., additional, Joosten, K., additional, and Hulst, J., additional
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- 2017
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13. 361 Protein and Energy Intake on Day 4 at the Picu: Predictor for Outcome?
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Augustus, M E, primary, Olieman, J F, additional, and Joosten, K F M, additional
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- 2010
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14. PP423 TYPE AND INTAKE OF NUTRITION ON DAY 4 AT THE PICU: PREDICTOR FOR OUTCOME?
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Olieman, J., primary, Augustus, M., additional, and Joosten, K., additional
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- 2010
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15. Computercriminaliteit en accountant
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Olieman, J. T., primary
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- 1994
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16. PROTEIN AND ENERGY INTAKE ON DAY 4 AT THE PICU PREDICTOR FOR OUTCOME
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Augustus, M. E., Olieman, J. F., and Joosten, K. F.M.
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- 2010
17. Prospective evaluation and follow-up of nutritional status of children hospitalized in secondary-care level hospitals: a multicentre study.
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Hulst J, van de Vorst K, Olieman J, Hendriks D, Oudshoorn J, Plötz F, Roskam M, van der Schoor S, Tramper-Stranders G, Verhoeven J, van Wering H, Winder E, and Joosten K
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- Humans, Female, Prospective Studies, Male, Child, Preschool, Infant, Child, Follow-Up Studies, Netherlands epidemiology, Malnutrition epidemiology, Malnutrition diagnosis, Hospitalization statistics & numerical data, Secondary Care Centers statistics & numerical data, Patient Discharge statistics & numerical data, Nutritional Support, Length of Stay statistics & numerical data, Child Nutrition Disorders epidemiology, Adolescent, Nutritional Status, Nutrition Assessment
- Abstract
Although disease-associated undernutrition is still an important problem in hospitalized children that is often underrecognized, follow-up studies evaluating post-discharge nutritional status of children with undernutrition are lacking. The aim of this multicentre prospective observational cohort study was to assess the rate of acute undernutrition (AU) and/or having a high nutritional risk (HR) in children on admission to seven secondary-care level Dutch hospitals and to evaluate the nutritional course of AU/HR group during admission and post-discharge. STRONG
kids was used to indicate HR, and AU was based on anthropometric data ( z -score < -2 for weight-for-age (WFA; <1 year) or weight-for-height (WFH; ≥1 year)). In total, 1985 patients were screened for AU/HR over a 12-month period. On admission, AU was present in 9.9% of screened children and 6.2% were classified as HR; 266 (13.4%) children comprised the AU/HR group (median age 2.4 years, median length of stay 3 days). In this group, further nutritional assessment by a dietitian during hospitalization occurred in 44% of children, whereas 38% received nutritional support. At follow-up 4-8 weeks post-discharge, 101 out of orginal 266 children in the AU/HR group (38%) had available paired anthropometric measurements to re-assess nutrition status. Significant improvement of WFA/WFH compared to admission (-2.48 vs. -1.51 SD; p < 0.001) and significant decline in AU rate from admission to outpatient follow-up (69.3% vs. 35.6%; p < 0.001) were shown. In conclusion, post-discharge nutritional status of children with undernutrition and/or high nutritional risk on admission to secondary-care level pediatric wards showed significant improvement, but about one-third remained undernourished. Findings warrant the need for a tailored post-discharge nutritional follow-up., Competing Interests: Koen F.M. Joosten and Jessie M. Hulst report receiving a grant from Nutricia Netherlands BV (Zoetermeer, the Netherlands) to support the conduct of the study. All other authors have no conflicts of interests to disclose.- Published
- 2024
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18. Nutritional intake and gastro-intestinal symptoms in critically ill COVID-19 patients.
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Lakenman PLM, van Schie JC, van der Hoven B, Baart SJ, Eveleens RD, van Bommel J, Olieman JF, and Joosten KFM
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- Adult, Humans, Male, Middle Aged, Female, Critical Illness therapy, Intensive Care Units, Eating, Diarrhea epidemiology, COVID-19 complications, Gastrointestinal Diseases epidemiology, Gastrointestinal Diseases etiology
- Abstract
Background & Aims: Critically ill COVID-19 patients seem hypermetabolic and difficult to feed enterally, due to gastro-intestinal (GI) symptoms such as high gastric residual volumes (GRV) and diarrhea. Our aim was to describe the association of nutritional intake and GI symptoms during first 14 days of ICU admission., Methods: Observational study including critically ill adult COVID-19 patients. Data on nutritional intake [enteral nutrition (EN) or parenteral nutrition] and GI symptoms were collected during 14 days after ICU admission. Target energy and protein feeding goals were calculated conform ESPEN guidelines. GI symptoms included GRV (ml/d), vomiting, abdominal distension, and faeces (ml/d). High GRV's were classified as ≥2 times ≥150 ml/d and diarrhea as Bristol stool chart ≥6. GI symptoms were defined as mild if at least one symptom occurred and as moderate when ≥2 symptoms occurred. Acute gastrointestinal injury (AGI) grades of III were classified as GI dysfunction and grades of IV were considered as GI failure with severe impact on distant organs. Linear mixed model analysis was performed to explore the development of nutritional intake and GI symptoms over time at day (D) 0, 4, 10, and 14., Results: One hundred and fifty patients were included [75% male; median age 64 years (IQR 54-70)]. BMI upon admission was 28 kg/m
2 (IQR 25-33), of which 43% obese (BMI > 30 kg/m2 ). Most patients received EN during admission (98% D4; 96% D10-14). Mean energy goals increased from 87% at D4 to 93% D10-14 and protein goals (g/kg) were increasingly achieved during admission (84% D4; 93% D10-14). Presence of moderate GI symptoms decreased (10% D0; 6% D4-10; 5% D14), reversely mild GI symptoms increased. Occurrence of GI dysfunction fluctuated (1% D0; 18% D4; 12% D10; 8% D14) and none of patients developed grade IV GI failure. Development of high GRV fluctuated (5% D0; 23% D4; 14% D10; 8% D14) and occurrence of diarrhea slightly increased during admission (5% D0; 22% D4; 25% D10; 27% D14). Linear mixed models showed only an association between AGI grades III and lower protein intake at day 10 (p = 0.020)., Conclusion: Occurrence of GI symptoms was limited and seems no major barrier for EN in our group of critically COVID-19 patients. Nutritional intake was just below requirements during the first 14 days of ICU admission. The effect on nutritional status remains to be studied., Competing Interests: Conflict of interest None declared., (Copyright © 2022 The Author(s). Published by Elsevier Ltd.. All rights reserved.)- Published
- 2022
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19. Energy expenditure and feeding practices and tolerance during the acute and late phase of critically ill COVID-19 patients.
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Lakenman PLM, van der Hoven B, Schuijs JM, Eveleens RD, van Bommel J, Olieman JF, and Joosten KFM
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- Adult, Basal Metabolism, Body Mass Index, COVID-19 complications, COVID-19 therapy, Critical Care, Disease Progression, Energy Intake, Female, Gastrointestinal Diseases etiology, Humans, Male, Middle Aged, Nitrogen urine, Parenteral Nutrition, Respiration, Artificial, Rest, SARS-CoV-2, COVID-19 metabolism, Critical Illness therapy, Energy Metabolism, Enteral Nutrition, Nutritional Requirements
- Abstract
Background & Aims: Different metabolic phases can be distinguished in critical illness, which influences nutritional treatment. Achieving optimal nutritional treatment during these phases in critically ill patients is challenging. COVID-19 patients seem particularly difficult to feed due to gastrointestinal problems. Our aim was to describe measured resting energy expenditure (mREE) and feeding practices and tolerance during the acute and late phases of critical illness in COVID-19 patients., Methods: Observational study including critically ill mechanically ventilated adult COVID-19 patients. Indirect calorimetry (Q-NRG+, Cosmed) was used to determine mREE during the acute (day 0-7) and late phase (>day 7) of critical illness. Data on nutritional intake, feeding tolerance and urinary nitrogen loss were collected simultaneously. A paired sample t-test was performed for mREE in both phases., Results: We enrolled 21 patients with a median age of 59 years [44-66], 67% male and median BMI of 31.5 kg/m
2 [25.7-37.8]. Patients were predominantly fed with EN in both phases. No significant difference in mREE was observed between phases (p = 0.529). Sixty-five percent of the patients were hypermetabolic in both phases. Median delivery of energy as percentage of mREE was higher in the late phase (94%) compared to the acute phase (70%) (p = 0.001). Urinary nitrogen losses were significant higher in the late phase (p = 0.003)., Conclusion: In both the acute and late phase, the majority of the patients were hypermetabolic and fed enterally. In the acute phase patients were fed hypocaloric whereas in the late phase this was almost normocaloric, conform ESPEN guidelines. No significant difference in mREE was observed between phases. Hypermetabolism in both phases in conjunction with an increasing loss of urinary nitrogen may indicate that COVID-19 patients remain in a prolonged acute, catabolic phase., Competing Interests: Declaration of competing interest None Declared., (Copyright © 2021 The Author(s). Published by Elsevier Ltd.. All rights reserved.)- Published
- 2021
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20. Body Composition Using Air Displacement Plethysmography in Children With Intestinal Failure Receiving Long-Term Home Parenteral Nutrition.
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Neelis E, Kouwenhoven S, Olieman J, Tabbers M, Jonkers C, Wells J, Fewtrell M, Wijnen R, Rings E, de Koning B, and Hulst J
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- Adipose Tissue, Adolescent, Body Mass Index, Child, Child, Preschool, Cohort Studies, Humans, Intestinal Diseases therapy, Prospective Studies, Body Composition, Parenteral Nutrition, Home, Plethysmography
- Abstract
Background: Children with intestinal failure (IF) are at risk of growth failure, but little information about body composition is available. Our aim was to assess body composition using air displacement plethysmography (ADP) and relate it to clinical and growth parameters., Methods: In this prospective descriptive observational 2-center cohort study, children aged 2-18 years receiving home parenteral nutrition (PN) for ≥6 months underwent ADP measurement. Fat mass index (FMI) and fat-free mass index (FFMI) standard deviation scores (SDSs) were calculated to normalize for small body size., Results: Twenty-one out of 22 children, median age 7.4 years, underwent successful ADP measurement after a median PN duration of 5.5 years. They were significantly lighter (median weight for age SDS -0.71, P = 0.004) and shorter (median height for age SDS -1.55, P < 0.001) than the normal population mean; 52% were growing below target height range. They had low FFMI (median SDS -1.53, P < 0.001) and high FMI (median SDS 0.80, P = 0.002). Weight for height and body mass index (BMI) were significantly associated with FFMI and BMI with FMI, but children with the same weight and height showed different body composition. In 13 patients with 1-year follow-up, growth and body composition did not change significantly., Conclusion: Children with IF receiving long-term PN show lower FFM and higher FM than healthy children. Additionally, children with similar routine growth parameters showed different body composition. Further studies should evaluate the effect of a patient-tailored approach including physical activity and nutrition advice based on body composition., (© 2019 American Society for Parenteral and Enteral Nutrition.)
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- 2020
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21. Nutritional Feeding Strategies in Pediatric Intestinal Failure.
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Olieman J and Kastelijn W
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- Adaptation, Physiological, Child, Humans, Intestines, Milk, Human, Intestinal Diseases therapy, Nutritional Support
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Intestinal failure is defined as a critical reduction of the gut mass or function, below the minimum needed to absorb nutrients and fluids. The ultimate goal in intestinal failure is to promote bowel adaptation and reach enteral autonomy while a healthy growth and development is maintained. The condition is heterogeneous and complex. Therefore, recommendations for the type and duration of parenteral, enteral, and oral nutrition are variable, with the child's age as an additional key factor. The aim of this review is to provide an overview of nutritional feeding strategies in this heterogeneous population. Different perspectives on nutritional management, nutrition and adaptation, and microbiome and nutrition will be discussed., Competing Interests: The authors declare no conflict of interest.
- Published
- 2020
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22. Outpatient initiation of the ketogenic diet in children with pharmacoresistant epilepsy: An effectiveness, safety and economic perspective.
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van der Louw E, Olieman J, Poley MJ, Wesstein T, Vehmeijer F, Catsman-Berrevoets C, and Neuteboom R
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- Adolescent, Child, Child, Preschool, Diet, Ketogenic economics, Female, Health Care Costs, Humans, Infant, Inpatients, Male, Outpatients, Retrospective Studies, Diet, Ketogenic methods, Drug Resistant Epilepsy diet therapy
- Abstract
Background: Children with pharmacoresistant epilepsy usually receive ketogenic diet (KD) as an inpatient, which makes it an expensive treatment., Objective: To compare the effectiveness, safety, and costs of outpatient versus inpatient initiated KD., Design: Retrospective observational non-inferiority study., Patients/setting: Patients (1-18 years of age) who started KD either inpatient or outpatient., Main Outcome Measures: Effectiveness was defined as ≥50% seizure reduction. Safety was measured by the numbers of emergency visits and complications. Economic impact was analyzed by calculating total costs of treatment., Statistical Analyses: Non-inferiority of outpatient initiation was tested using 95% confidence intervals of the differences in effectiveness and safety endpoints between groups with non-inferiority margins of 10%. Nonparametric bootstrap techniques were used to derive a 95% confidence interval for the mean difference in total costs between the groups., Results: Hundred and five patients started KD in the period 2001 to 2017: 43 inpatient and 62 outpatient. At three months, the KD was effective in 61% of outpatients versus 63% of inpatients. The KD was considered safe in 36% of the outpatients, as compared to 29% in the inpatients. Outpatient initiation was shown to be non-inferior to inpatient initiation in terms of safety. Total health care costs of outpatient initiation were € 2901, as compared to € 8195 of inpatient initiation per patient (mean difference € 5294, 95% CI; -€ 7653 to -€ 2935)., Conclusions: Our study suggests that outpatient KD initiation is no worse than inpatient initiation in terms of effectiveness and safety, while carrying lower health care costs., (Copyright © 2019 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.)
- Published
- 2019
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23. Growth, Body Composition, and Micronutrient Abnormalities During and After Weaning Off Home Parenteral Nutrition.
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Neelis E, Olieman J, Rizopoulos D, Wijnen R, Rings E, de Koning B, and Hulst J
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- Body Composition, Child, Preschool, Databases, Factual, Female, Gastrointestinal Diseases immunology, Gastrointestinal Diseases microbiology, Gastrointestinal Microbiome, Gastrointestinal Tract growth & development, Gastrointestinal Tract microbiology, Gastroschisis therapy, Humans, Immune System growth & development, Immune System microbiology, Incidence, Male, Micronutrients metabolism, Nutritional Status, Respiratory Tract Infections immunology, Respiratory Tract Infections microbiology, Retrospective Studies, United Kingdom epidemiology, Gastrointestinal Diseases epidemiology, Gastroschisis immunology, Gastroschisis microbiology, Parenteral Nutrition, Home adverse effects, Respiratory Tract Infections epidemiology
- Abstract
Objectives: The aim of the study is to assess growth, body composition, and micronutrient abnormalities in children with intestinal failure (IF) over time, both during and after weaning off parenteral nutrition (PN)., Methods: Retrospective study in children on home PN between 2001 and 2015. Weight-for-age (WFA) and height-for-age (HFA) SD scores (SDS) were calculated, as well as fat mass (FM) and fat-free mass (FFM) SDS obtained by dual energy x-ray absorptiometry. The course of growth parameters and body composition was analyzed with linear-mixed models. All micronutrient measurements during the study period were obtained., Results: Fifty-two patients were included with a median follow-up of 3.4 years. Seventy-one percent weaned off after a median PN duration of 0.9 years. One year after the start of PN, 28 patients were still PN-dependent with median WFA-SDS of -0.66 and median HFA-SDS of -0.96, both significantly lower than zero. Catch-up growth was achieved during PN, but HFA-SDS decreased after weaning (P = 0.0001). At a median age of 6.2 years, median %FM SDS was 0.30 and FFM SDS was -1.21, the latter significantly lower than zero. Frequent micronutrient abnormalities during PN were vitamin A (90%), zinc (87%), and iron (76%) and after weaning vitamin A (94%), E (61%), and 25-OH vitamin D (59%)., Conclusions: Children with IF demonstrate abnormal growth and body composition and frequent micronutrient abnormalities. Longitudinal evaluation showed that catch-up growth occurs during PN, but height SDS decreases after weaning. This underlines the need for close monitoring, also after reaching enteral autonomy.
- Published
- 2018
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24. Bone health of children with intestinal failure measured by dual energy X-ray absorptiometry and digital X-ray radiogrammetry.
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Neelis E, Rijnen N, Sluimer J, Olieman J, Rizopoulos D, Wijnen R, Rings E, de Koning B, and Hulst J
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- Child, Female, Hand diagnostic imaging, Humans, Intestinal Diseases complications, Intestinal Diseases diet therapy, Intestines pathology, Lumbar Vertebrae diagnostic imaging, Male, Osteoporosis complications, Radiography methods, Reproducibility of Results, Retrospective Studies, Sensitivity and Specificity, X-Rays, Absorptiometry, Photon methods, Bone Density physiology, Intestinal Diseases pathology, Osteoporosis diagnostic imaging, Parenteral Nutrition
- Abstract
Background & Aims: Children with intestinal failure (IF) receiving long-term parenteral nutrition (PN) are at risk of developing low bone mineral density (BMD). Next to the dual energy X-ray absorptiometry (DXA) method, digital X-ray radiogrammetry (DXR) using the BoneXpert software has become available to obtain the Bone Health Index (BHI) in hand radiographs. In this study we 1) evaluated the prevalence of low BMD in children with IF using DXA and DXR, 2) compared DXA and DXR results, and 3) aimed to identify factors associated with low BMD., Methods: A retrospective study was performed including all children with IF between 2000 and 2015 who underwent a DXA measurement and/or a hand radiograph. Z-scores of BMD total body (BMD TB) and lumbar spine (BMD LS), bone mineral apparent density (BMAD) and bone health index (BHI) were collected. A low BMD and low BHI were defined as a Z-score ≤ -2. DXA and DXR results were compared for cases in which a DXA and hand radiograph were performed within a 6 months' interval., Results: Forty-six children were included. Overall, 24.3% of the children had a low BMD at the first DXA at a median age of 6 years; correction for growth failure (n = 6) reduced this to 16.2%. Fifty percent had a low BHI at the first hand radiograph. Median DXA and BHI Z-scores were significantly lower than reference scores. Age, duration of PN and surgical IF were related to lower Z-scores at the first DXA. Paired DXA and DXR results (n = 18) were compared, resulting in a Cohen's kappa of 0.746 ('substantial') for BMD TB. Spearman's correlation coefficient for BHI and BMD TB Z-scores was 0.856 (p < 0.001). Hand radiography had a sensitivity of 90% and specificity of 86% (BMD TB)., Conclusions: Up to 50% of the children had a low BMD. Children with IF have a significantly poorer bone health than the reference population, also after weaning off PN. Bone health assessment by DXA and DXR showed good agreement, especially for Z-scores ≤ -2. DXR assessment using BoneXpert software seems to be feasible for monitoring of bone health in children with IF., (Copyright © 2017 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.)
- Published
- 2018
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25. Taurolidine in Pediatric Home Parenteral Nutrition Patients.
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Hulshof EC, Hanff LM, Olieman J, de Vette S, Driessen GJ, Meeussen C, and Escher JC
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- Anti-Infective Agents administration & dosage, Child, Preschool, Humans, Infant, Infant, Newborn, Parenteral Nutrition, Home adverse effects, Parenteral Nutrition, Home methods, Retrospective Studies, Taurine administration & dosage, Taurine therapeutic use, Thiadiazines administration & dosage, Anti-Infective Agents therapeutic use, Bacteremia drug therapy, Bacteremia epidemiology, Bacteremia prevention & control, Catheter-Related Infections drug therapy, Catheter-Related Infections epidemiology, Catheter-Related Infections prevention & control, Parenteral Nutrition, Home statistics & numerical data, Taurine analogs & derivatives, Thiadiazines therapeutic use
- Abstract
To reduce the incidence of catheter-related bloodstream infections in home parenteral nutrition patients, the use of taurolidine was introduced in the Sophia Children's Hospital in 2011. This introduction led to a reduction in catheter-related bloodstream infections: 12.7/1000 catheter days before the use of taurolidine, compared with 4.3/1000 catheter days afterwards (n = 7) [relative risk = 0.36, 95% confidence interval: 0.20-0.65 (P = 0.018)].
- Published
- 2017
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26. Promoting intestinal adaptation by nutrition and medication.
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Neelis EG, Olieman JF, Hulst JM, de Koning BA, Wijnen RM, and Rings EH
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- Enteral Nutrition, Humans, Intestine, Small surgery, Nutritional Status, Short Bowel Syndrome surgery, Adaptation, Physiological, Intestine, Small physiopathology, Parenteral Nutrition, Short Bowel Syndrome physiopathology
- Abstract
The ultimate goal in the treatment of short bowel syndrome is to wean patients off parenteral nutrition, by promoting intestinal adaptation. Intestinal adaptation is the natural compensatory process that occurs after small bowel resection. Stimulating the remaining bowel with enteral nutrition can enhance this process. Additionally, medication can be used to either reduce factors that complicate the adaptation process or to stimulate intestinal adaptation, such as antisecretory drugs and several growth factors. The aim of this review was to provide an overview of the best nutritional strategies and medication that best promote intestinal adaptation., (Copyright © 2016 Elsevier Ltd. All rights reserved.)
- Published
- 2016
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27. Achieving energy goals at day 4 after admission in critically ill children; predictive for outcome?
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de Betue CT, van Steenselen WN, Hulst JM, Olieman JF, Augustus M, Mohd Din SH, Verbruggen SC, Tibboel D, and Joosten KF
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- Acute Disease, Adolescent, Anti-Bacterial Agents administration & dosage, Child, Child, Preschool, Enteral Nutrition, Hospitalization, Humans, Infant, Infant, Newborn, Intensive Care Units, Pediatric, Length of Stay, Malnutrition complications, Netherlands, Nutritional Status, Prospective Studies, Respiration, Artificial, Treatment Outcome, Critical Illness therapy, Energy Intake, Malnutrition therapy
- Abstract
Background & Aims: Adequate nutritional intake is essential during pediatric intensive care admission. We investigated whether achievement of energy intake goals at day 4 after admission and route of nutrition were associated with improved outcome., Methods: Observational study using prospectively acquired data. Patients receiving enteral and/or parenteral nutrition were included. The energy intake target range at day 4 after admission was 90-110% of resting energy expenditure +10%. Acute malnutrition was defined as weight-for-age <-2 SD. Clinical outcome measures were length of stay, days on ventilator, duration of antibiotics and number of new infections. Data as median (min-max)., Results: Of 325 subjects (age 0.14 (0.0-18.0) year), 19% were acutely malnourished upon admission. Median 86% of energy goals were administered via the enteral route. With enteral energy intake, 7% of patients were fed within the target range, 50% were fed below and 43% were fed above the target range. In a subgroup (n = 223) the acutely malnourished proportion at discharge (26%) was not significantly different from that upon admission (22%). Whether the energy intake was below, within or above the target range did not affect changes in clinical outcome, nor did the route of nutrition., Conclusions: Acute malnutrition was highly prevalent upon admission and at discharge. With our nutritional protocol we achieved high rates of (enteral) energy intake. A high percentage of our population received enteral energy above the target energy range. However, there was no association between the amount of energy intake or route of nutrition and clinical outcome., (Copyright © 2014 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.)
- Published
- 2015
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