Author: "Okamoto W." - Searchworks@Jio Institute Digital Library Search Results

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223 results on '"Okamoto W."'

1. A phase II study to explore biomarkers for the use of mFOLFOX6/XELOX plus bevacizumab as a first-line chemotherapy in patients with metastatic colorectal cancer (WJOG7612GTR)

Author: Okamoto, W., Sakai, K., Makiyama, A., Yamamoto, Y., Shitara, K., Denda, T., Izawa, N., Nakano, Y., Nishina, T., Esaki, T., Hara, H., Miura, Y., Boku, N., Yamazaki, K., Hironaka, S., Misumi, T., Hyodo, I., Muro, K., and Nishio, K.
Published: 2022
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2. Erdafitinib in patients with advanced solid tumours with FGFR alterations (RAGNAR): an international, single-arm, phase 2 study

Author: Pant, S, Schuler, M, Iyer, G, Witt, O, Doi, T, Qin, S, Tabernero, J, Reardon, D, Massard, C, Minchom, A, Lugowska, I, Carranza, O, Arnold, D, Gutierrez, M, Winter, H, Stuyckens, K, Crow, L, Najmi, S, Hammond, C, Thomas, S, Santiago-Walker, A, Triantos, S, Sweiti, H, Loriot, Y, Greco, M, Coward, J, Joshua, A, Karapetis, C, Hart, C, Zhang, A, Prenen, H, Goeminne, J, Machiels, J, Rottey, S, Corassa, M, Molin, G, Tiscoski, K, Jardim, D, Mak, M, Fu, W, Yao, H, Huang, J, Jiang, H, Chen, B, Yan, D, Yang, Y, Le Tourneau, C, Penel, N, Salas, S, Blay, J, Brachet, P, Durando, X, Emambux, S, Ravaud, A, Folprecht, G, Ahrens, M, Golf, A, Haag, G, Lordick, F, Desuki, A, Cazzaniga, M, Ciardiello, F, Milella, M, Koyama, T, Hirooka, Y, Okamoto, W, Aogi, K, Kuboki, Y, Lee, J, Kim, S, Ahn, M, Chang, J, Kim, Y, Nam, D, Park, J, Paz-Ares, L, Moreno, V, Cervantes, A, Calvo, M, Falcon, A, Gonzalez, A, Martinez Bueno, A, Garcia-Corbacho, J, Longo, F, Yen, C, Chen, J, Hou, M, Chao, Y, Rau, K, Chiu, T, Feng, Y, Hsu, C, Huang, W, Lai, K, Yeh, S, Palmer, D, Welsh, L, Plummer, R, Bilen, M, Arrowsmith, E, Spigel, D, Zandberg, D, Doroshow, D, Lu-Emerson, C, Moezi, M, Paulson, S, Ward, P, Chaves, J, Grigg, C, Hussein, A, Manda, S, Monticelli, M, Qamar, R, Richey, S, Tamura, D, Wilks, S, Pant S., Schuler M., Iyer G., Witt O., Doi T., Qin S., Tabernero J., Reardon D. A., Massard C., Minchom A., Lugowska I., Carranza O., Arnold D., Gutierrez M., Winter H., Stuyckens K., Crow L., Najmi S., Hammond C., Thomas S., Santiago-Walker A., Triantos S., Sweiti H., Loriot Y., Greco M. A., Coward J., Joshua A., Karapetis C., Hart C., Zhang A., Prenen H., Goeminne J. -C., Machiels J. -P., Rottey S., Corassa M., Molin G. Z. D., Tiscoski K., Jardim D. L. F., Mak M., Fu W., Yao H., Huang J., Jiang H., Chen B., Yan D., Yang Y., Le Tourneau C., Penel N., Salas S., Blay J. -Y., Brachet P. -E., Durando X., Emambux S., Ravaud A., Folprecht G., Ahrens M., Golf A., Haag G. M., Lordick F., Desuki A., Cazzaniga M., Ciardiello F., Milella M., Koyama T., Hirooka Y., Okamoto W., Aogi K., Kuboki Y., Lee J., Kim S. -B., Ahn M. -J., Chang J. H., Kim Y. -M., Nam D. -H., Park J. -S., Paz-Ares L., Moreno V., Cervantes A., Calvo M., Falcon A., Gonzalez A., Martinez Bueno A., Garcia-Corbacho J., Longo F., Yen C. -J., Chen J. -S., Hou M. -F., Chao Y., Rau K. -M., Chiu T. -J., Feng Y. -H., Hsu C. -H., Huang W. -T., Lai K. -M., Yeh S. -P., Palmer D., Welsh L., Plummer R., Bilen M., Arrowsmith E., Spigel D. R., Zandberg D. P., Doroshow D., Lu-Emerson C., Moezi M., Paulson S., Reardon D., Ward P., Chaves J., Grigg C., Hussein A., Manda S., Monticelli M., Qamar R., Richey S. L., Tamura D., Wilks S., Pant, S, Schuler, M, Iyer, G, Witt, O, Doi, T, Qin, S, Tabernero, J, Reardon, D, Massard, C, Minchom, A, Lugowska, I, Carranza, O, Arnold, D, Gutierrez, M, Winter, H, Stuyckens, K, Crow, L, Najmi, S, Hammond, C, Thomas, S, Santiago-Walker, A, Triantos, S, Sweiti, H, Loriot, Y, Greco, M, Coward, J, Joshua, A, Karapetis, C, Hart, C, Zhang, A, Prenen, H, Goeminne, J, Machiels, J, Rottey, S, Corassa, M, Molin, G, Tiscoski, K, Jardim, D, Mak, M, Fu, W, Yao, H, Huang, J, Jiang, H, Chen, B, Yan, D, Yang, Y, Le Tourneau, C, Penel, N, Salas, S, Blay, J, Brachet, P, Durando, X, Emambux, S, Ravaud, A, Folprecht, G, Ahrens, M, Golf, A, Haag, G, Lordick, F, Desuki, A, Cazzaniga, M, Ciardiello, F, Milella, M, Koyama, T, Hirooka, Y, Okamoto, W, Aogi, K, Kuboki, Y, Lee, J, Kim, S, Ahn, M, Chang, J, Kim, Y, Nam, D, Park, J, Paz-Ares, L, Moreno, V, Cervantes, A, Calvo, M, Falcon, A, Gonzalez, A, Martinez Bueno, A, Garcia-Corbacho, J, Longo, F, Yen, C, Chen, J, Hou, M, Chao, Y, Rau, K, Chiu, T, Feng, Y, Hsu, C, Huang, W, Lai, K, Yeh, S, Palmer, D, Welsh, L, Plummer, R, Bilen, M, Arrowsmith, E, Spigel, D, Zandberg, D, Doroshow, D, Lu-Emerson, C, Moezi, M, Paulson, S, Ward, P, Chaves, J, Grigg, C, Hussein, A, Manda, S, Monticelli, M, Qamar, R, Richey, S, Tamura, D, Wilks, S, Pant S., Schuler M., Iyer G., Witt O., Doi T., Qin S., Tabernero J., Reardon D. A., Massard C., Minchom A., Lugowska I., Carranza O., Arnold D., Gutierrez M., Winter H., Stuyckens K., Crow L., Najmi S., Hammond C., Thomas S., Santiago-Walker A., Triantos S., Sweiti H., Loriot Y., Greco M. A., Coward J., Joshua A., Karapetis C., Hart C., Zhang A., Prenen H., Goeminne J. -C., Machiels J. -P., Rottey S., Corassa M., Molin G. Z. D., Tiscoski K., Jardim D. L. F., Mak M., Fu W., Yao H., Huang J., Jiang H., Chen B., Yan D., Yang Y., Le Tourneau C., Penel N., Salas S., Blay J. -Y., Brachet P. -E., Durando X., Emambux S., Ravaud A., Folprecht G., Ahrens M., Golf A., Haag G. M., Lordick F., Desuki A., Cazzaniga M., Ciardiello F., Milella M., Koyama T., Hirooka Y., Okamoto W., Aogi K., Kuboki Y., Lee J., Kim S. -B., Ahn M. -J., Chang J. H., Kim Y. -M., Nam D. -H., Park J. -S., Paz-Ares L., Moreno V., Cervantes A., Calvo M., Falcon A., Gonzalez A., Martinez Bueno A., Garcia-Corbacho J., Longo F., Yen C. -J., Chen J. -S., Hou M. -F., Chao Y., Rau K. -M., Chiu T. -J., Feng Y. -H., Hsu C. -H., Huang W. -T., Lai K. -M., Yeh S. -P., Palmer D., Welsh L., Plummer R., Bilen M., Arrowsmith E., Spigel D. R., Zandberg D. P., Doroshow D., Lu-Emerson C., Moezi M., Paulson S., Reardon D., Ward P., Chaves J., Grigg C., Hussein A., Manda S., Monticelli M., Qamar R., Richey S. L., Tamura D., and Wilks S.
Abstract: Background: FGFR alterations are reported across various malignancies and might act as oncogenic drivers in multiple histologies. Erdafitinib is an oral, selective pan-FGFR tyrosine kinase inhibitor with activity in FGFR-altered advanced urothelial carcinoma. We aimed to evaluate the safety and activity of erdafitinib in previously treated patients with FGFR-altered advanced solid tumours. Methods: The single-arm, phase 2 RAGNAR study was conducted at 156 investigative centres (hospitals or oncology practices that are qualified oncology study centres) across 15 countries. The study consisted of four cohorts based on tumour histology and patient age; the results reported in this Article are for the primary cohort of the study, defined as the Broad Panel Cohort, which was histology-agnostic. We recruited patients aged 12 years or older with advanced or metastatic tumours of any histology (except urothelial cancer) with predefined FGFR1–4 alterations (mutations or fusions according to local or central testing). Eligible patients had disease progression on at least one previous line of systemic therapy and no alternative standard therapy available to them, and an Eastern Cooperative Oncology Group performance status of 0–1 (or equivalent for adolescents aged 12–17 years). Patients received once-daily oral erdafitinib (8 mg/day with provision for pharmacodynamically guided up-titration to 9 mg/day) on a continuous 21-day cycle until disease progression or intolerable toxicity. The primary endpoint was objective response rate by independent review committee according to Response Evaluation Criteria In Solid Tumors (RECIST), version 1.1, or Response Assessment In Neuro-Oncology (RANO). The primary analysis was conducted on the treated population of the Broad Panel Cohort. This ongoing study is registered with ClinicalTrials.gov, number NCT04083976. Findings: Patients were recruited between Dec 5, 2019, and Feb 15, 2022. Of 217 patients treated with erdafitinib, 97 (45%) pa
Published: 2023

3. 1259TiP Investigator-initiated phase II study of nivolumab plus low-dose ipilimumab as first-line therapy for microsatellite instability—high advanced gastric or esophagogastric junction cancer (NO LIMIT, WJOG13320G/CA209-7W7)

Author: Kawakami, H., primary, Kadowaki, S., additional, Hirata, K., additional, Tsuda, M., additional, Esaki, T., additional, Sugimoto, N., additional, Makiyama, A., additional, Machida, N., additional, Hirano, H., additional, Hara, H., additional, Kawakami, T., additional, Okamoto, W., additional, Yabusaki, H., additional, Komatsu, Y., additional, Hironaka, S., additional, and Muro, K., additional
Published: 2022
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4. 1705P HER2 intratumoral genetic and non-genetic heterogeneity in metastatic colorectal cancer

Author: Sawada, K., primary, Nitta, H., additional, Nakamura, Y., additional, Okamoto, W., additional, Taniguchi, H., additional, Komatsu, Y., additional, Hara, H., additional, Kato, T., additional, Nishina, T., additional, Ohta, T., additional, Esaki, T., additional, Yoshino, T., additional, and Fujii, S., additional
Published: 2022
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5. P-141 Lenvatinib activates potential anti-tumor immunity by increasing infiltration of immune cells and interferon response in tumor microenvironment of advanced hepatocellular carcinoma

Author: Yamauchi, M., primary, Ono, A., additional, Amioka, K., additional, Fujii, Y., additional, Uchikawa, S., additional, Fujino, H., additional, Nakahara, T., additional, Murakami, E., additional, Okamoto, W., additional, Kawaoka, T., additional, Miki, D., additional, Tsuge, M., additional, Imamura, M., additional, Nelson, H., additional, Kato, Y., additional, Kimura, M., additional, Suzuki, N., additional, Aikata, H., additional, and Chayama, K., additional
Published: 2022
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6. PD-013 Final survival results of a multicenter phase I/II study of TAS-102 with bevacizumab for metastatic colorectal cancer patients refractory to standard therapies (C-TASK FORCE)

Author: Yoshino, T., Kuboki, Y., Nishina, T., Shinozaki, E., Yamazaki, K., Shitara, K., Okamoto, W., Kajiwara, T., Matsumoto, T., Tsushima, T., Mochizuki, N., Fukutani, M., Nakamoto, M., Hasegawa, H., Sugama, A., Nomura, S., Sato, A., and Ohtsu, A.
Published: 2016
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7. Roles of BIM induction and survivin downregulation in lapatinib-induced apoptosis in breast cancer cells with HER2 amplification

Author: Tanizaki, J, Okamoto, I, Fumita, S, Okamoto, W, Nishio, K, and Nakagawa, K
Published: 2011
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8. ANTITUMOR ACTION OF THE MET TYROSINE KINASE INHIBITOR CRIZOTINIB (PF-02341066) IN GASTRIC CANCER POSITIVE FOR MET AMPLIFICATION

Author: Okamoto, W., Okamoto, I., Arao, T., Nishina, S.-i., Ueda, S., Kawakami, H., Yanagihara, K., Kurata, T., Nishio, K., and Nakagawa, K.
Published: 2012

9. ROLES OF BIM INDUCTION AND SURVIVIN DOWN-REGULATION IN LAPATINIB-INDUCED APOPTOSIS IN BREAST CANCER CELLS WITH HER2 AMPLIFICATION

Author: Tanizaki, J., Okamoto, I., Fumita, S., Okamoto, W., and Nakagawa, K.
Published: 2012

10. The crystal structure of recombinant human adult hemoglobin

Author: Kihira, K., primary, Funaki, R., additional, Okamoto, W., additional, Endo, C., additional, Morita, Y., additional, and Komatsu, T., additional
Published: 2020
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11. Microsatellite instability status in metastatic colorectal cancer and effect of immune checkpoint inhibitors on survival in MSI-high metastatic colorectal cancer

Author: Okamoto, W., primary, Nakamura, Y., additional, Shiozawa, M., additional, Komatsu, Y., additional, Denda, T., additional, Hara, H., additional, Kagawa, Y., additional, Narita, Y., additional, Kawakami, H., additional, Esaki, T., additional, Nishina, T., additional, Izawa, N., additional, Ando, K., additional, Moriwaki, T., additional, Kato, T., additional, Nagashima, F., additional, Satoh, T., additional, Nomura, S., additional, Yoshino, T., additional, and Akagi, K., additional
Published: 2019
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12. Prognostic and predictive impact on FMS-like tyrosine kinase 3 (FLT3) amplification in patients with metastatic colorectal cancer

Author: Hasegawa, H., primary, Taniguchi, H., additional, Kato, T., additional, Fujii, S., additional, Ebi, H., additional, Shiozawa, M., additional, Yuki, S., additional, Masuishi, T., additional, Kato, K., additional, Izawa, N., additional, Moriwaki, T., additional, Kagawa, Y., additional, Sakamoto, Y., additional, Okamoto, W., additional, Nakamura, Y., additional, Yamazaki, K., additional, and Yoshino, T., additional
Published: 2019
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13. TRIUMPH: Primary efficacy of a phase II trial of trastuzumab (T) and pertuzumab (P) in patients (pts) with metastatic colorectal cancer (mCRC) with HER2 (ERBB2) amplification (amp) in tumour tissue or circulating tumour DNA (ctDNA): A GOZILA sub-study

Author: Nakamura, Y., primary, Okamoto, W., additional, Kato, T., additional, Hasegawa, H., additional, Kato, K., additional, Iwasa, S., additional, Esaki, T., additional, Komatsu, Y., additional, Masuishi, T., additional, Nishina, T., additional, Nomura, S., additional, Fukui, M., additional, Matsuda, S., additional, Sato, A., additional, Fujii, S., additional, Odegaard, J.I., additional, Olsen, S., additional, and Yoshino, T., additional
Published: 2019
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14. Below-gap recombination dynamics in GaN revealed by time-resolved and two-wavelength excited photoluminescence

Author: Kamata, N., Zanardi Ocampo, J.M., Okamoto, W., Hoshino, K., Someya, T., Arakawa, Y., and Yamada, K.
Published: 2002
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15. The nationwide cancer genome screening project in Japan, SCRUM-Japan GI-SCREEN: Efficient identification of cancer genome alterations in advanced esophageal cancer

Author: Kato, K., primary, Kojima, T., additional, Saeki, H., additional, Hara, H., additional, Kajiwara, T., additional, Hironaka, S., additional, Nakatsumi, H., additional, Kadowaki, S., additional, Kagawa, Y., additional, Esaki, T., additional, Moriwaki, T., additional, Kobayashi, T., additional, Izawa, N., additional, Nomura, S., additional, Kuwata, T., additional, Fujii, S., additional, Okamoto, W., additional, Shitara, K., additional, Ohtsu, A., additional, and Yoshino, T., additional
Published: 2018
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16. RET rearrangements may arise following anti-EGFR therapy in advanced colorectal cancer

Author: Rich, T.A., primary, Clifton, K., additional, Grothey, A., additional, Hendifar, A., additional, Henry, D.H., additional, Kagawa, Y., additional, Nakamura, Y., additional, Okamoto, W., additional, Tan, B.R., additional, Sherrill, G., additional, Yoshino, T., additional, Raymond, V.M., additional, Shiotsu, Y., additional, Lanman, R.B., additional, and Morris, V., additional
Published: 2018
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17. The nationwide cancer genome screening project in Japan, SCRUM Japan GISCREEN: Efficient identification of cancer genome alterations in advanced biliary tract cancer

Author: Morizane, C., primary, Komatsu, Y., additional, Takahashi, H., additional, Ueno, M., additional, Furuse, J., additional, Kudo, T., additional, Itoh, S., additional, Shimizu, S., additional, Nakamura, K., additional, Kamata, K., additional, Ohtsubo, K., additional, Mizukami, T., additional, Kagawa, Y., additional, Nomura, S., additional, Kuwata, T., additional, Fujii, S., additional, Okamoto, W., additional, Shitara, K., additional, Ohtsu, A., additional, and Yoshino, T., additional
Published: 2018
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18. The nationwide cancer genome screening project in Japan, SCRUM-Japan GI-SCREEN: Efficient identification of cancer genome alterations in advanced pancreatic cancer

Author: Izawa, N., primary, Morizane, C., additional, Takahashi, H., additional, Ueno, M., additional, Kawamoto, Y., additional, Okano, N., additional, Shimizu, S., additional, Sudo, K., additional, Itoh, S., additional, Asagi, A., additional, Kagawa, Y., additional, Kamata, K., additional, Kudo, T., additional, Nomura, S., additional, Kuwata, T., additional, Fujii, S., additional, Okamoto, W., additional, Shitara, K., additional, Ohtsu, A., additional, and Yoshino, T., additional
Published: 2018
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19. A clinical validation study of RASKET-B: A multiple detection kit for RAS and BRAF gene mutations in colorectal cancer

Author: Okamoto, W., primary, Muro, K., additional, Taniguchi, H., additional, Akagi, K., additional, Hara, H., additional, Nishina, T., additional, Kajiwara, T., additional, Denda, T., additional, Hironaka, S., additional, Kudo, T., additional, Satoh, T., additional, and Yoshino, T., additional
Published: 2017
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20. The nationwide cancer genome screening project in Japan SCRUM-Japan GI-SCREEN: Efficient identification of cancer genome alterations in advanced small intestine cancer

Author: Takayoshi, K., primary, Okamoto, W., additional, Hironaka, S., additional, Honma, Y., additional, Ebi, H., additional, Nakanishi, R., additional, Kajiwara, T., additional, Kudo, T., additional, Tamura, T., additional, Komatsu, Y., additional, Hara, H., additional, Naruge, D., additional, Moriwaki, T., additional, Miki, I., additional, Sudo, T., additional, Nomura, S., additional, Fujii, S., additional, Shitara, K., additional, Ohtsu, A., additional, and Yoshino, T., additional
Published: 2017
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21. Clinical utility of quasi-monomorphic variation range (QMVR) on the determination of microsatellite instability (MSI) status in patients (pts) with colorectal cancer (CRC): GI-SCREEN-CRC-MSI sub-study 01

Author: Okamoto, W., primary, Bando, H., additional, Fukui, T., additional, Yamanaka, T., additional, Akagi, K., additional, and Yoshino, T., additional
Published: 2017
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22. TRIUMPH Study: A multicenter Phase II study to evaluate efficacy and safety of combination therapy with trastuzumab and pertuzumab in patients with HER2-positive metastatic colorectal cancer (EPOC1602)

Author: Nakamura, Y., primary, Okamoto, W., additional, Sawada, K., additional, Komatsu, Y., additional, Kato, K., additional, Taniguchi, H., additional, Kato, T., additional, Nishina, T., additional, Esaki, T., additional, Nomura, H., additional, Fukutani, M., additional, Fukui, M., additional, Hasegawa, H., additional, Yonemura, M., additional, Fuse, N., additional, Sato, A., additional, Fujii, S., additional, Ohtsu, A., additional, and Yoshino, T., additional
Published: 2017
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23. 636P - Prognostic and predictive impact on FMS-like tyrosine kinase 3 (FLT3) amplification in patients with metastatic colorectal cancer

Author: Hasegawa, H., Taniguchi, H., Kato, T., Fujii, S., Ebi, H., Shiozawa, M., Yuki, S., Masuishi, T., Kato, K., Izawa, N., Moriwaki, T., Kagawa, Y., Sakamoto, Y., Okamoto, W., Nakamura, Y., Yamazaki, K., and Yoshino, T.
Published: 2019
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24. 614P - Microsatellite instability status in metastatic colorectal cancer and effect of immune checkpoint inhibitors on survival in MSI-high metastatic colorectal cancer

Author: Okamoto, W., Nakamura, Y., Shiozawa, M., Komatsu, Y., Denda, T., Hara, H., Kagawa, Y., Narita, Y., Kawakami, H., Esaki, T., Nishina, T., Izawa, N., Ando, K., Moriwaki, T., Kato, T., Nagashima, F., Satoh, T., Nomura, S., Yoshino, T., and Akagi, K.
Published: 2019
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25. 526PD - TRIUMPH: Primary efficacy of a phase II trial of trastuzumab (T) and pertuzumab (P) in patients (pts) with metastatic colorectal cancer (mCRC) with HER2 (ERBB2) amplification (amp) in tumour tissue or circulating tumour DNA (ctDNA): A GOZILA sub-study

Author: Nakamura, Y., Okamoto, W., Kato, T., Hasegawa, H., Kato, K., Iwasa, S., Esaki, T., Komatsu, Y., Masuishi, T., Nishina, T., Nomura, S., Fukui, M., Matsuda, S., Sato, A., Fujii, S., Odegaard, J.I., Olsen, S., and Yoshino, T.
Published: 2019
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26. 180P Clinical outcome of anal squamous cell carcinoma treated with chemoradiotherapy with 5-fluorouracil plus mitomycin C

Author: Doi, A., primary, Bando, H., additional, Kawazoe, A., additional, Fukuoka, S., additional, Kuboki, Y., additional, Shitara, K., additional, Okamoto, W., additional, Kojima, T., additional, Doi, T., additional, Ohtsu, A., additional, and Yoshino, T., additional
Published: 2016
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27. Comparative sequence analysis between primary colorectal cancer, metastasis and recurrent metastasis after adjuvant FOLFOX chemotherapy

Author: Harada, K., primary, Okamoto, W., additional, Mimaki, S., additional, Kawamoto, Y., additional, Bando, H., additional, Yuki, S., additional, Yoshino, T., additional, Komatsu, Y., additional, Ohtsu, A., additional, Sakamoto, N., additional, and Tsuchihara, K., additional
Published: 2016
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28. 644P - The nationwide cancer genome screening project in Japan, SCRUM-Japan GI-SCREEN: Efficient identification of cancer genome alterations in advanced pancreatic cancer

Author: Izawa, N., Morizane, C., Takahashi, H., Ueno, M., Kawamoto, Y., Okano, N., Shimizu, S., Sudo, K., Itoh, S., Asagi, A., Kagawa, Y., Kamata, K., Kudo, T., Nomura, S., Kuwata, T., Fujii, S., Okamoto, W., Shitara, K., Ohtsu, A., and Yoshino, T.
Published: 2018
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29. 627P - The nationwide cancer genome screening project in Japan, SCRUM-Japan GI-SCREEN: Efficient identification of cancer genome alterations in advanced esophageal cancer

Author: Kato, K., Kojima, T., Saeki, H., Hara, H., Kajiwara, T., Hironaka, S., Nakatsumi, H., Kadowaki, S., Kagawa, Y., Esaki, T., Moriwaki, T., Kobayashi, T., Izawa, N., Nomura, S., Kuwata, T., Fujii, S., Okamoto, W., Shitara, K., Ohtsu, A., and Yoshino, T.
Published: 2018
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30. 623PD - The nationwide cancer genome screening project in Japan, SCRUM Japan GISCREEN: Efficient identification of cancer genome alterations in advanced biliary tract cancer

Author: Morizane, C., Komatsu, Y., Takahashi, H., Ueno, M., Furuse, J., Kudo, T., Itoh, S., Shimizu, S., Nakamura, K., Kamata, K., Ohtsubo, K., Mizukami, T., Kagawa, Y., Nomura, S., Kuwata, T., Fujii, S., Okamoto, W., Shitara, K., Ohtsu, A., and Yoshino, T.
Published: 2018
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31. 482P - RET rearrangements may arise following anti-EGFR therapy in advanced colorectal cancer

Author: Rich, T.A., Clifton, K., Grothey, A., Hendifar, A., Henry, D.H., Kagawa, Y., Nakamura, Y., Okamoto, W., Tan, B.R., Sherrill, G., Yoshino, T., Raymond, V.M., Shiotsu, Y., Lanman, R.B., and Morris, V.
Published: 2018
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32. 2328 Outcomes in 44 Patients with metastatic esophageal squamous cell carcinoma treated in phase 1 trials: the NCCHE Experience

Author: Noguchi, M., primary, Kojima, T., additional, Shitara, K., additional, Kawazoe, A., additional, Fukuoka, S., additional, Kuboki, Y., additional, Hatogai, K., additional, Bando, H., additional, Okamoto, W., additional, Doi, T., additional, Ohtsu, A., additional, and Yoshino, T., additional
Published: 2015
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33. 2116 A multicenter phase I/II study of TAS-102 with bevacizumab for metastatic colorectal cancer refractory to standard therapies (C-TASK FORCE)

Author: Yamazaki, K., primary, Kuboki, Y., additional, Nishina, T., additional, Shinozaki, E., additional, Shitara, K., additional, Okamoto, W., additional, Kajiwara, T., additional, Matsumoto, T., additional, Tsushima, T., additional, Mochizuki, N., additional, Fukutani, M., additional, Nakamoto, M., additional, Hasegawa, Y., additional, Sugama, A., additional, Nomura, S., additional, Sato, A., additional, Ohtsu, A., additional, and Yoshino, T., additional
Published: 2015
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34. 3430 Clinical outcomes in 21 patients with gastrointestinal stromal tumor (GIST) treated in phase I trials: The NCCHE Experience

Author: Nagatani, Y., primary, Shitara, K., additional, Bando, H., additional, Okamoto, W., additional, Kojima, T., additional, Yoshino, T., additional, Nishida, T., additional, and Doi, T., additional
Published: 2015
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35. 2107 Safety and efficacy on TAS-102 monotherapy in patients with metastatic colorectal cancer according to previous regorafenib

Author: Kotani, D., primary, Shitara, K., additional, Fukuoka, S., additional, Kuboki, Y., additional, Bando, H., additional, Okamoto, W., additional, Kojima, T., additional, Doi, T., additional, Ohtsu, A., additional, and Yoshino, T., additional
Published: 2015
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36. 465 Detection of somatic mutations and gene amplification using Oncomine Cancer Research Panel with biopsy samples from patients with advanced gastric cancer

Author: Okamoto, W., primary, Shitara, K., additional, Takahashi, H., additional, Naito, Y., additional, Kuwata, T., additional, Bando, H., additional, Kuboki, Y., additional, Matsumoto, S., additional, Miki, I., additional, Yamanaka, T., additional, Ohtsu, A., additional, Esumi, H., additional, Ochiai, A., additional, Yoshino, T., additional, and Tsuchihara, K., additional
Published: 2015
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37. PD-017 A multicenter phase I/II study of TAS-102 with bevacizumab for metastatic colorectal cancer refractory to standard therapies (C-TASK FORCE)

Author: Nishina, T., primary, Kuboki, Y., additional, Shinozaki, E., additional, Yamazaki, K., additional, Kajiwara, T., additional, Shitara, K., additional, Matsumoto, T., additional, Tsushima, T., additional, Okamoto, W., additional, Mochizuki, N., additional, Nomura, S., additional, Sato, A., additional, Ohtsu, A., additional, and Yoshino, T., additional
Published: 2015
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38. 188P - A clinical validation study of RASKET-B: A multiple detection kit for RAS and BRAF gene mutations in colorectal cancer

Author: Okamoto, W., Muro, K., Taniguchi, H., Akagi, K., Hara, H., Nishina, T., Kajiwara, T., Denda, T., Hironaka, S., Kudo, T., Satoh, T., and Yoshino, T.
Published: 2017
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39. 612TiP - TRIUMPH Study: A multicenter Phase II study to evaluate efficacy and safety of combination therapy with trastuzumab and pertuzumab in patients with HER2-positive metastatic colorectal cancer (EPOC1602)

Author: Nakamura, Y., Okamoto, W., Sawada, K., Komatsu, Y., Kato, K., Taniguchi, H., Kato, T., Nishina, T., Esaki, T., Nomura, H., Fukutani, M., Fukui, M., Hasegawa, H., Yonemura, M., Fuse, N., Sato, A., Fujii, S., Ohtsu, A., and Yoshino, T.
Published: 2017
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40. 567P - Clinical utility of quasi-monomorphic variation range (QMVR) on the determination of microsatellite instability (MSI) status in patients (pts) with colorectal cancer (CRC): GI-SCREEN-CRC-MSI sub-study 01

Author: Okamoto, W., Bando, H., Fukui, T., Yamanaka, T., Akagi, K., and Yoshino, T.
Published: 2017
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41. 765P - The nationwide cancer genome screening project in Japan SCRUM-Japan GI-SCREEN: Efficient identification of cancer genome alterations in advanced small intestine cancer

Author: Takayoshi, K., Okamoto, W., Hironaka, S., Honma, Y., Ebi, H., Nakanishi, R., Kajiwara, T., Kudo, T., Tamura, T., Komatsu, Y., Hara, H., Naruge, D., Moriwaki, T., Miki, I., Sudo, T., Nomura, S., Fujii, S., Shitara, K., Ohtsu, A., and Yoshino, T.
Published: 2017
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42. Clinical Validation of a Novel Multiplex Kit for All Ras Mutations in Colorectal Cancer: Results of Rasket(Ras Key Testing) Prospective Multicenter Study

Author: Yamaguchi, K., primary, Akagi, K., additional, Muro, K., additional, Taniguchi, H., additional, Nishina, T., additional, Kajiwara, T., additional, Denda, T., additional, Hironaka, S., additional, Kudo, T., additional, Satoh, T., additional, Okamoto, W., additional, and Yoshino, T., additional
Published: 2014
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43. 356 - Comparative sequence analysis between primary colorectal cancer, metastasis and recurrent metastasis after adjuvant FOLFOX chemotherapy

Author: Harada, K., Okamoto, W., Mimaki, S., Kawamoto, Y., Bando, H., Yuki, S., Yoshino, T., Komatsu, Y., Ohtsu, A., Sakamoto, N., and Tsuchihara, K.
Published: 2016
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44. Use of Duloxetine for Treatment of Neuropathic Pain in Cancer Patients

Author: Matsuoka, H., primary, Makimura, C., additional, Okamoto, K., additional, Okamoto, W., additional, Fujisaka, Y., additional, Tsurutani, J., additional, Ootsuka, M., additional, and Nakagawa, K., additional
Published: 2012
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45. Pharmacokinetics (PK) and Safety of Tesetaxel, a Novel Oral Taxane, in Japanese Patients (PTS) with Advanced Solid Tumors

Author: Tanaka, K., primary, Kurata, T., additional, Fujisaka, Y., additional, Kawakami, H., additional, Hayashi, H., additional, Cousin, T., additional, Okamoto, W., additional, Kudoh, T., additional, Satoh, T., additional, and Nakagawa, K., additional
Published: 2012
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46. Differential roles of STAT3 depending on the mechanism of STAT3 activation in gastric cancer cells

Author: Okamoto, W, primary, Okamoto, I, additional, Arao, T, additional, Yanagihara, K, additional, Nishio, K, additional, and Nakagawa, K, additional
Published: 2011
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47. Thymidylate synthase as a determinant of pemetrexed sensitivity in non-small cell lung cancer

Author: Takezawa, K, primary, Okamoto, I, additional, Okamoto, W, additional, Takeda, M, additional, Sakai, K, additional, Tsukioka, S, additional, Kuwata, K, additional, Yamaguchi, H, additional, Nishio, K, additional, and Nakagawa, K, additional
Published: 2011
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48. Central Japan Synchrotron Radiation Research Facility Project-(II)

Author: Yamamoto, N., primary, Takashima, Y., additional, Katoh, M., additional, Hosaka, M., additional, Takami, K., additional, Morimoto, H., additional, Hori, Y., additional, Sasaki, S., additional, Koda, S., additional, Ito, T., additional, Sakurai, I., additional, Hara, H., additional, Okamoto, W., additional, Watanabe, N., additional, Takeda, Y., additional, Garrett, R., additional, Gentle, I., additional, Nugent, K., additional, and Wilkins, S., additional
Published: 2010
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49. Phase I clinical and biomarker study of BIBF 1120, an oral multitarget tyrosine kinase inhibitor, in patients with advanced solid tumors (ST): Impact of CD133- and CD117-positive cells on a biomarker of an antiangiogenic inhibitor

Author: Okamoto, I., primary, Kaneda, H., additional, Satoh, T., additional, Okamoto, W., additional, Terashima, M., additional, Arao, T., additional, Nishio, K., additional, Nakagawa, K., additional, Konishi, K., additional, and Kaiser, R., additional
Published: 2009
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50. 3061 POSTER Phase I/II study of novel oral fluoropyrimidine S-1 in combination with oxaliplatin (SOX) as first-line chemotherapy for metastatic colorectal cancer (mCRC)

Author: Tahara, M., primary, Yamada, Y., additional, Ohtsu, A., additional, Shirao, K., additional, Shimada, Y., additional, Sasaki, Y., additional, Yamamoto, W., additional, Satoh, T., additional, Okamoto, W., additional, and Tanigawara, Y., additional
Published: 2007
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