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1. Time elapsed from definitive diagnosis to surgery for osteonecrosis of the femoral head: a nationwide observational study in Japan

Author: Nakamura, Junichi, primary, Fukushima, Wakaba, additional, Ando, Wataru, additional, Hagiwara, Shigeo, additional, Kawarai, Yuya, additional, Shiko, Yuki, additional, Kawasaki, Yohei, additional, Sakai, Takashi, additional, Ito, Kazuya, additional, Arishima, Yoshiya, additional, Chosa, Etsuo, additional, Fujimoto, Yusuke, additional, Fujiwara, Kazuo, additional, Hasegawa, Yukiharu, additional, Hayashi, Shinya, additional, Imagama, Takashi, additional, Inaba, Yutaka, additional, Ishibashi, Yasuyuki, additional, Ishidou, Yasuhiro, additional, Ito, Hideya, additional, Ito, Hiroshi, additional, Ito, Juji, additional, Jinno, Tetsuya, additional, Kabata, Tamon, additional, Kaku, Nobuhiro, additional, Kaneuji, Ayumi, additional, Kishida, Shunji, additional, Kobayashi, Seneki, additional, Komiya, Setsuro, additional, Kubo, Toshikazu, additional, Majima, Tokifumi, additional, Mashima, Naohiko, additional, Mawatari, Masaaki, additional, Miki, Hidenobu, additional, Miyatake, Kazumasa, additional, Motomura, Goro, additional, Nagoya, Satoshi, additional, Nakamura, Hiroaki, additional, Nakamura, Yoshihide, additional, Nakanishi, Ryosuke, additional, Nakashima, Yasuharu, additional, Nakasone, Satoshi, additional, Nishii, Takashi, additional, Nishiyama, Takayuki, additional, Ohta, Yoichi, additional, Ohzono, Kenji, additional, Osaki, Makoto, additional, Sasaki, Kan, additional, Seki, Taisuke, additional, Shishido, Takaaki, additional, Shoji, Takeshi, additional, Sudo, Akihiro, additional, Takagi, Michiaki, additional, Takahashi, Daisuke, additional, Takao, Masaki, additional, Tanaka, Sakae, additional, Tanaka, Takeyuki, additional, Tetsunaga, Tomonori, additional, Ueshima, Keiichiro, additional, Yamamoto, Kengo, additional, Yamamoto, Takuaki, additional, Yamamoto, Yuji, additional, Yamasaki, Takuma, additional, Yasunaga, Yuji, additional, and Sugano, Nobuhiko, additional
Published: 2024
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2. Progressive Bone Destruction in Rapidly Destructive Coxopathy Is Characterized by Elevated Serum Levels of Matrix Metalloprotease-3 and C-Reactive Protein

Author: Ando, Wataru, Hashimoto, Yoshichika, Yasui, Hirohiko, Ogawa, Takeshi, Koyama, Tsuyoshi, Tsuda, Takayuki, and Ohzono, Kenji
Published: 2022
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3. Excellent bone plug–socket integration at 8 weeks after anterior cruciate ligament reconstruction using an adjustable-length loop cortical fixation device

Author: Uchida, Ryohei, Nakamura, Norimasa, Suzuki, Tomoyuki, Kusano, Masashi, Mae, Tatsuo, Ohzono, Kenji, and Toritsuka, Yukiyoshi
Published: 2019
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4. Long-term results of Birmingham hip resurfacing arthroplasty in Asian patients

Author: Uemura, Keisuke, Takao, Masaki, Hamada, Hidetoshi, Sakai, Takashi, Ohzono, Kenji, and Sugano, Nobuhiko
Published: 2018
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5. Healing of tibial bone tunnels after bone grafting for staged revision anterior cruciate ligament surgery: A prospective computed tomography analysis

Author: Uchida, Ryohei, Toritsuka, Yukiyoshi, Mae, Tatsuo, Kusano, Masashi, and Ohzono, Kenji
Published: 2016
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6. Natural Course and the JIC Classification of Osteonecrosis of the Femoral Head

Author: Sugano, Nobuhiko, Ohzono, Kenji, Koo, Kyung-Hoi, editor, Mont, Michael A., editor, and Jones, Lynne C., editor
Published: 2014
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7. Comparison between component designs with different femoral head size in metal-on-metal total hip arthroplasty; multicenter randomized prospective study

Author: Ando, Wataru, Yamamoto, Kengo, Atsumi, Takashi, Tamaoki, Satoshi, Oinuma, Kazuhiro, Shiratsuchi, Hideaki, Tokunaga, Hirohiko, Inaba, Yutaka, Kobayashi, Naomi, Aihara, Masaharu, and Ohzono, Kenji
Published: 2015
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8. Virtual Implantation Using the ROBODOC Preoperative Planning Workstation

Author: Koyama, Tsuyoshi, Sugano, Nobuhiko, Nishii, Takashi, Sakai, Takashi, Haraguchi, Keiji, Nishihara, Shunsaku, Hagio, Keisuke, Nakamura, Nobuo, Ohzono, Kenji, Ochi, Takahiro, Matsui, Nobuo, editor, Taneda, Yoichi, editor, and Yoshida, Yukio, editor
Published: 2001
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9. A Novel Combined Acetabular and Femoral Computer Navigation System

Author: Sugano, Nobuhiko, Nishii, Takashi, Sakai, Takashi, Nishihara, Shunsaku, Ohzono, Kenji, Yonenobu, Kazuo, Sato, Yoshinobu, Sasama, Toshihiko, Nakahodo, Kei, Tamura, Shinichi, Ochi, Takahiro, Matsui, Nobuo, editor, Taneda, Yoichi, editor, and Yoshida, Yukio, editor
Published: 2001
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10. Cementless Total Hip Arthroplasty Using a Custom-Made Femoral Component with Sand-Blasted Surface

Author: Sakai, Takashi, Sugano, Nobuhiko, Matsui, Minoru, Lee, Seung-Bak, Nishii, Takashi, Haraguchi, Keiji, Nakata, Katsuya, Ochi, Takahiro, Yoshikawa, Hideki, Ohzono, Kenji, Matsui, Nobuo, editor, Taneda, Yoichi, editor, and Yoshida, Yukio, editor
Published: 2001
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11. Three-Dimensional Reconstruction and Quantification of Hip Joint Cartilages from Magnetic Resonance Images

Author: Sato, Yoshinobu, Kubota, Tetsuya, Nakanishi, Katsuyuki, Tanaka, Hisashi, Sugano, Nobuhiko, Nishii, Takashi, Ohzono, Kenji, Nakamura, Hironobu, Ochi, Takahiro, Tamura, Shinichi, Goos, Gerhard, editor, Hartmanis, Juris, editor, van Leeuwen, Jan, editor, Taylor, Chris, editor, and Colchester, Alain, editor
Published: 1999
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12. Effects of Stem Loosening on Periprosthetic Bone Remodeling After Cementless Hip Replacement

Author: Nishii, Takashi, Tanaka, Masao, Sugano, Nobuhiko, Tamura, Shinichi, Ohzono, Kenji, Ochi, Takahiro, and Takahashi, Hideaki E., editor
Published: 1999
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13. The intraoperative gap difference (flexion gap minus extension gap) is altered by insertion of the trial femoral component

Author: Hananouchi, Takehito, Yamamoto, Kengo, Ando, Wataru, Fudo, Kazumasa, and Ohzono, Kenji
Published: 2012
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14. Outcome of anatomical double-bundle ACL reconstruction using hamstring tendons via an outside-in approach

Author: Amano, Hiroshi, Toritsuka, Yukiyoshi, Uchida, Ryohei, Mae, Tatsuo, Ohzono, Kenji, and Shino, Konsei
Published: 2015
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15. Dual tunnel medial patellofemoral ligament reconstruction for patients with patellar dislocation using a semitendinosus tendon autograft

Author: Toritsuka, Yukiyoshi, Amano, Hiroshi, Mae, Tatsuo, Uchida, Ryohei, Hamada, Masayuki, Ohzono, Kenji, and Shino, Konsei
Published: 2011
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16. Novel susceptibility loci for steroid-associated osteonecrosis of the femoral head in systemic lupus erythematosus

Author: Suetsugu, Hiroyuki, primary, Kim, Kwangwoo, additional, Yamamoto, Takuaki, additional, Bang, So-Young, additional, Sakamoto, Yuma, additional, Shin, Jung-Min, additional, Sugano, Nobuhiko, additional, Kim, Ji Soong, additional, Mukai, Masaya, additional, Lee, Yeon-Kyung, additional, Ohmura, Koichiro, additional, Park, Dae Jin, additional, Takahashi, Daisuke, additional, Ahn, Ga-Young, additional, Karino, Kohei, additional, Kwon, Young-Chang, additional, Miyamura, Tomoya, additional, Kim, Jihye, additional, Nakamura, Junichi, additional, Motomura, Goro, additional, Kuroda, Takeshi, additional, Niiro, Hiroaki, additional, Miyamoto, Takeshi, additional, Takeuchi, Tsutomu, additional, Ikari, Katsunori, additional, Amano, Koichi, additional, Tada, Yoshifumi, additional, Yamaji, Ken, additional, Shimizu, Masato, additional, Atsumi, Takashi, additional, Seki, Taisuke, additional, Tanaka, Yoshiya, additional, Kubo, Toshikazu, additional, Hisada, Ryo, additional, Yoshioka, Tomokazu, additional, Yamazaki, Mihoko, additional, Kabata, Tamon, additional, Kajino, Tomomichi, additional, Ohta, Yoichi, additional, Okawa, Takahiro, additional, Naito, Yohei, additional, Kaneuji, Ayumi, additional, Yasunaga, Yuji, additional, Ohzono, Kenji, additional, Tomizuka, Kohei, additional, Koido, Masaru, additional, Matsuda, Koichi, additional, Okada, Yukinori, additional, Suzuki, Akari, additional, Kim, Bong-Jo, additional, Kochi, Yuta, additional, Lee, Hye-Soon, additional, Ikegawa, Shiro, additional, Bae, Sang-Cheol, additional, and Terao, Chikashi, additional
Published: 2021
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17. Compared Microangiographic Images of Osteonecrosis of the Femoral Head and Osteoarthritis of the Hip

Author: Ohzono, Kenji, Sugano, Nobuhiko, Nakamura, Nobuo, Ono, Keiro, Schoutens, A., editor, Arlet, J., editor, Gardeniers, J. W. M., editor, and Hughes, S. P. F., editor
Published: 1993
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18. Comparison between highly cross-linked and conventional polyethylene in total knee arthroplasty

Author: Minoda, Yukihide, Aihara, Masaharu, Sakawa, Akira, Fukuoka, Shinichi, Hayakawa, Keiko, Tomita, Masuhiro, Umeda, Naoya, and Ohzono, Kenji
Published: 2009
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19. Clinical Efficacy of Mechanical Thromboprophylaxis Without Anticoagulant Drugs for Elective Hip Surgery in an Asian Population

Author: Sugano, Nobuhiko, Miki, Hidenobu, Nakamura, Nobuo, Aihara, Masaharu, Yamamoto, Kengo, and Ohzono, Kenji
Published: 2009
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20. Range of Motion of Standard and High-Flexion Cruciate Retaining Total Knee Prostheses

Author: Minoda, Yukihide, Aihara, Masaharu, Sakawa, Akira, Fukuoka, Shinichi, Hayakawa, Keiko, and Ohzono, Kenji
Published: 2009
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21. Modular acetabular reconstructive cup in acetabular revision total hip arthroplasty at a minimum ten year follow-up

Author: Sakai, Takashi, Ohzono, Kenji, Nishii, Takashi, Takao, Masaki, Miki, Hidenobu, Nakamura, Nobuo, and Sugano, Nobuhiko
Published: 2013
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22. Anterior Impingement Test for Labral Lesions Has High Positive Predictive Value

Author: Hananouchi, Takehito, Yasui, Yukihiko, Yamamoto, Kengo, Toritsuka, Yukiyoshi, and Ohzono, Kenji
Published: 2012
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23. High Survival of Dome Pelvic Osteotomy in Patients with Early Osteoarthritis from Hip Dysplasia

Author: Sakai, Takashi, Nishii, Takashi, Takao, Masaki, Ohzono, Kenji, and Sugano, Nobuhiko
Published: 2012
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24. Japanese Orthopaedic Association Hip Disease Evaluation Questionnaire (JHEQ): a patient-based evaluation tool for hip-joint disease. The Subcommittee on Hip Disease Evaluation of the Clinical Outcome Committee of the Japanese Orthopaedic Association

Author: Matsumoto, Tadami, Kaneuji, Ayumi, Hiejima, Yoshimitsu, Sugiyama, Hajime, Akiyama, Haruhiko, Atsumi, Takashi, Ishii, Masaji, Izumi, Kiyoko, Ichiseki, Toru, Ito, Hiroshi, Okawa, Takahiro, Ohzono, Kenji, Otsuka, Hiromi, Kishida, Shunji, Kobayashi, Seneki, Sawaguchi, Takeshi, Sugano, Nobuhiko, Nakajima, Ikumasa, Nakamura, Shigeru, Hasegawa, Yukiharu, Fukuda, Kanji, Fujii, Genji, Mawatari, Taro, Mori, Satoshi, Yasunaga, Yuji, and Yamaguchi, Masao
Published: 2012
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25. Acetabular component orientation in intra- and postoperative positions in total hip arthroplasty

Author: Hayakawa, Keiko, Minoda, Yukihide, Aihara, Masaharu, Sakawa, Akira, Ohzono, Kenji, and Tada, Koichi
Published: 2009
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26. Outcome of double-bundle ACL reconstruction using hamstring tendons

Author: Toritsuka, Yukiyoshi, Amano, Hiroshi, Kuwano, Masahiro, Iwai, Takao, Mae, Tatsuo, Ohzono, Kenji, and Shino, Konsei
Published: 2009
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27. Proximal bone remodelling differed between two types of titanium long femoral components after cementless revision arthroplasty

Author: Iwana, Daiki, Nishii, Takashi, Miki, Hidenobu, Sugano, Nobuhiko, Sakai, Takashi, Ohzono, Kenji, and Yoshikawa, Hideki
Published: 2008
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28. Symptomatic Adjacent Segment Pathology after Posterior Lumbar Interbody Fusion for Adult Low-Grade Isthmic Spondylolisthesis

Author: Sakaura, Hironobu, Yamashita, Tomoya, Miwa, Toshitada, Ohzono, Kenji, and Ohwada, Tetsuo
Published: 2013
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29. Synovial chondromatosis of the acromioclavicular joint

Author: Kudawara, Ikuo, Aono, Masanari, Ohzono, Kenji, and Mano, Masayuki
Published: 2004
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30. Correlation between femoral neck version and strain on the femur after insertion of femoral prosthesis

Author: Umeda, Naoya, Saito, Masanobu, Sugano, Nobuhiko, Ohzono, Kenji, Nishii, Takashi, Sakai, Takashi, Yoshikawa, Hideki, Ikeda, Daisaku, and Murakami, Atsushi
Published: 2003
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31. Bone scintigraphy screening for osteonecrosis of the shoulder in patients with non-traumatic osteonecrosis of the femoral head

Author: Sakai, Takashi, Sugano, Nobuhiko, Nishii, Takashi, Miki, Hidenobu, Ohzono, Kenji, and Yoshikawa, Hideki
Published: 2002
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32. The 2001 revised criteria for diagnosis, classification, and staging of idiopathic osteonecrosis of the femoral head

Author: Sugano, Nobuhiko, Atsumi, Takashi, Ohzono, Kenji, Kubo, Toshikazu, Hotokebuchi, Takao, and Takaoka, Kunio
Published: 2002
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33. Femoral anteversion, femoral offset, and abductor lever arm after total hip arthroplasty using a modular femoral neck system

Author: Sakai, Takashi, Sugano, Nobuhiko, Ohzono, Kenji, Nishii, Takashi, Haraguchi, Keiji, and Yoshikawa, Hideki
Published: 2002
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34. Optimizing femoral anteversion and offset after total hip arthroplasty, using a modular femoral neck system: an experimental study

Author: Sakai, Takashi, Sugano, Nobuhiko, Nishii, Takashi, Haraguchi, Keiji, Ochi, Takahiro, and Ohzono, Kenji
Published: 2000
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35. Pathology of femoral head collapse following transtrochanteric rotational osteotomy for osteonecrosis

Author: Nakai, T., Masuhara, Kensaku, Nakase, Takanobu, Sugano, Nobuhiko, Ohzono, Kenji, and Ochi, Takahiro
Published: 2000
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36. Stem length and canal filling in uncemented custom-made total hip arthroplasty

Author: Sakai, T., Sugano, Nobuhiko, Nishii, Takashi, Haraguchi, Keiji, Ochi, Takahiro, and Ohzono, Kenji
Published: 1999
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37. Cementless Modular Total Hip Arthroplasty with Subtrochanteric Shortening Osteotomy for Hips with Developmental Dysplasia

Author: Takao, Masaki, Ohzono, Kenji, Nishii, Takashi, Miki, Hidenobu, Nakamura, Nobuo, and Sugano, Nobuhiko
Published: 2011
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38. Progressive Bone Destruction in Rapidly Destructive Coxopathy Is Characterized by Elevated Serum Levels of Matrix Metalloprotease-3 and C-Reactive Protein

Author: Ando, Wataru, primary, Hashimoto, Yoshichika, additional, Yasui, Hirohiko, additional, Ogawa, Takeshi, additional, Koyama, Tsuyoshi, additional, Tsuda, Takayuki, additional, and Ohzono, Kenji, additional
Published: 2020
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39. Analysis of Germline and Tumor Mutations of p53 Gene in Familial Occurrence of Soft Tissue Sarcomas

Author: Kudawara, Ikuo, Matsumine, Akihiko, and Ohzono, Kenji
Published: 2007
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40. Treatment of Relapsed Idiopathic Clubfoot by Complete Subtalar Release Combined With the Ilizarov Method

Author: Nakase, Takanobu, Yasui, Natsuo, Ohzono, Kenji, Shimizu, Nobuyuki, and Yoshikawa, Hideki
Published: 2006

41. A case of traumatic divergent fracture-dislocation of the elbow combined with Essex-Lopresti lesion in an adult

Author: Kazuki, Kenichi, Miyamoto, Takashi, and Ohzono, Kenji
Published: 2005

42. Sciatic nerve palsy after cementless total hip arthroplasty. Treatment by modular neck and calcar shortening: a case report

Author: Sakai, Takashi, Sugano, Nobuhiko, Fujii, Masakazu, Nishii, Takashi, Ohzono, Kenji, and Yoshikawa, Hideki
Published: 2002
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43. Three-Dimensional Reconstruction and Quantification of Hip Joint Cartilages from Magnetic Resonance Images

Author: Sato, Yoshinobu, primary, Kubota, Tetsuya, additional, Nakanishi, Katsuyuki, additional, Tanaka, Hisashi, additional, Sugano, Nobuhiko, additional, Nishii, Takashi, additional, Ohzono, Kenji, additional, Nakamura, Hironobu, additional, Ochi, Takahiro, additional, and Tamura, Shinichi, additional
Published: 1999
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44. Evaluation of Periprosthetic Bone-Remodeling After Cementless Total Hip Arthroplasty: The Influence of the Extent of Porous Coating*

Author: YAMAGUCHI, KATSUYUKI, MASUHARA, KENSAKU, OHZONO, KENJI, SUGANO, NOBUHIKO, NISHII, TAKASHI, and OCHI, TAKAHIRO
Published: 2000

45. Scintigraphic Assessment of the Rotated Femoral Head After Transtrochanteric Rotational Osteotomy for Osteonecrosis*

Author: NAKAI, TSUYOSHI, MASUHARA, KENSAKU, NAKASE, TAKANOBU, SUGANO, NOBUHIKO, OHZONO, KENJI, and OCHI, TAKAHIRO
Published: 2000

46. Stem fracture of the cementless spongy metal lübeck hip prosthesis

Author: Kishida, Yuki, Sugano, Nobuhiko, Ohzono, Kenji, Sakai, Takashi, Nishii, Takashi, and Yoshikawa, Hideki
Published: 2002
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47. The Metal-Cancellous Cementless Lubeck total hip arthroplasty: FIVE-TO-NINE-YEAR RESULTS

Author: Matsui, Minoru, Nakata, Katsuya, Masuhara, Kensaku, Ohzono, Kenji, Sugano, Nobuhiko, and Ochi, Takahiro
Published: 1998

48. Acetabular Osteolysis and Migration in Bipolar Arthroplasty of the Hip: Five- to 13-Year Follow-Up Study

Author: Nakata, Katsuya, Ohzono, Kenji, Masuhara, Kensaku, Matsui, Minoru, Hiroshima, Kazuo, and Ochi, Takahiro
Published: 1997

49. Early MRI findings of rapidly destructive coxopathy

Author: Sugano, Nobuhiko, Ohzono, Kenji, Nishii, Takashi, Sakai, Takashi, Haraguchi, Keiji, Yoshikawa, Hideki, and Kubo, Toshikazu
Published: 2001
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50. Genome-wide Association Study of Idiopathic Osteonecrosis of the Femoral Head

Author: Sakamoto, Yuma, Yamamoto, Takuaki, Sugano, Nobuhiko, Takahashi, Daisuke, Watanabe, Toshiyuki, Atsumi, Takashi, Nakamura, Junichi, Hasegawa, Yukiharu, Akashi, Koichi, Narita, Ichiei, Miyamoto, Takeshi, Takeuchi, Tsutomu, Ikari, Katsunori, Amano, Koichi, Fujie, Atsuhiro, Kubo, Toshikazu, Tada, Yoshifumi, Kaneuji, Ayumi, Nakamura, Hiroaki, Miyamura, Tomoya, Kabata, Tamon, Yamaji, Ken, Okawa, Takahiro, Sudo, Akihiro, Ohzono, Kenji, Tanaka, Yoshiya, Yasunaga, Yuji, Matsuda, Shuichi, Imai, Yuuki, Akiyama, Masato, Kubo, Michiaki, Kamatani, Yoichiro, Iwamoto, Yukihide, and Ikegawa, Shiro
Subjects: Osteoarthritis, Musculoskeletal abnormalities, Bone, Genome-wide association studies
Abstract: Idiopathic osteonecrosis of the femoral head (IONFH) is an ischemic disorder that causes bone necrosis of the femoral head, resulting in hip joint dysfunction. IONFH is a polygenic disease and steroid and alcohol have already known to increase its risk; however, the mechanism of IONFH remains to be elucidated. We performed a genome-wide association study using ~60, 000 subjects and found two novel loci on chromosome 20q12 and 12q24. Big data analyses identified LINC01370 as a candidate susceptibility gene in the 20q12 locus. Stratified analysis by IONFH risk factors suggested that the 12q24 locus was associated with IONFH through drinking capacity. Our findings would shed new light on pathophysiology of IONFH.
Published: 2017

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