115 results on '"Ohkubo, Takayuki"'
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2. Radiosynthesis of 18F-fluoroethylated tracers via a simplified one-pot 18F-fluoroethylation method using [18F]fluoroethyl tosylate
3. Simultaneous measurements of the molar radioactivity, radiochemical purity and chemical impurity in the [11C]choline injection using radio-HPLC with a corona-charged aerosol detector
4. Automated radiosynthesis of two 18F-labeled tracers containing 3-fluoro-2-hydroxypropyl moiety, [18F]FMISO and [18F]PM-PBB3, via [18F]epifluorohydrin
5. Potential for in vivo visualization of intracellular pH gradient in the brain using PET imaging.
6. O-[18F]fluoroalkylation of phenol derivatives with [18F] epifluorohydrin in the presence of t-Bu-P4 base
7. Automated radiosynthesis of [18F]FMeNER-D2 using the simplified one-pot 18F-fluoromethylation.
8. [18F]DAA1106: Automated radiosynthesis using spirocyclic iodonium ylide and preclinical evaluation for positron emission tomography imaging of translocator protein (18 kDa)
9. Comparison between [18F]fluorination and [18F]fluoroethylation reactions for the synthesis of the PDE10A PET radiotracer [18F]MNI-659
10. Developing new PET tracers to image the growth hormone secretagogue receptor 1a (GHS-R1a)
11. In vivovisualization of intracellular pH gradient in brain using PET imaging
12. A 211At-labelled mGluR1 inhibitor induces cancer senescence to elicit long-lasting anti-tumor efficacy
13. P-054 - O-[18F]fluoroalkylation of phenol derivatives with [18F] epifluorohydrin in the presence of t-Bu-P4 base
14. P-005 - Automated radiosynthesis of [18F]FMeNER-D2 using the simplified one-pot 18F-fluoromethylation.
15. Scandium triflate-catalyzed N-[18F]Fluoroalkylation of aryl- or heteroaryl-amines with [18F]epifluorohydrin under mild condi-tions
16. Radiosynthesis and in vivo evaluation of 11C-labeled BMS-193885 and its desmethyl analog as PET tracers for neuropeptide Y1 receptors
17. Automated radiosynthesis of [11C]MTP38—a phosphodiesterase 7 imaging tracer—using [11C]hydrogen cyanide for clinical applications
18. サイクロトロンによる放射性標識薬剤の製造・開発への利用状況<R2>
19. ecDHFRイメージング用の遺伝子レポーターPETトレーサー[18F]FHP-TMPの開発
20. Automated radiosynthesis of 18F-fluoromethylated tracers using the simplified one-pot 18F-fluoromethylation via [18F]fluoromethyl tosylate
21. Development of [18F]FHP-TMP as a PET gene reporter tracer for imaging of E.coli dihydrofolate reductase in the mammalian brain
22. Demonstration of intracellular pH-weighting PET imaging using a new-type PET probe responsible for monoacylglycerol lipase activity in the brain
23. Scandium Triflate-Catalyzed N-[18F]Fluoroalkylation of Aryl- Or Heteroaryl-Amines with [18F]Epifluorohydrin under Mild Conditions
24. Demonstration of intracellular pH-weighting PET imaging using a new-type PET probe responsible for monoacylglycerol lipase activity in the brain
25. Radiosynthesis and quality control testing of the tau imaging positron emission tomography tracer [18F]PM‐PBB3 for clinical applications
26. サイクロトロンによる放射性標識薬剤の製造・開発への利用状況
27. Automated radiosynthesis of [ 11 C]MTP38—a phosphodiesterase 7 imaging tracer—using [ 11 C]hydrogen cyanide for clinical applications
28. 簡易的1ポット[18F]フルオロアルキル化標識法を用いた[18F]フルオロメチルコリンの合成検討
29. Additional file 1 of Automated radiosynthesis of two 18F-labeled tracers containing 3-fluoro-2-hydroxypropyl moiety, [18F]FMISO and [18F]PM-PBB3, via [18F]epifluorohydrin
30. Automated radiosynthesis of two 18F-labeled tracers containing 3-fluoro-2-hydroxypropyl moiety, [18F]FMISO and [18F]PM-PBB3, via [18F]epifluorohydrin
31. [11C]SL25.1188の臨床提供に向けた安定的製造法及び品質検査法の確立
32. モノアシルグリセロールリパーゼを標的としたPETプローブを用いた脳内pHイメージング法の開発
33. 多種多様な診断及び治療用放射性薬剤の安定的製造
34. 様々な標識中間体を用いた標識合成法の開発
35. Development of 2-(2-(3-(4-([18F]Fluoromethoxy- d2)phenyl)-7-methyl-4-oxo-3,4-dihydroquinazolin-2-yl)ethyl)-4-isopropoxyisoindoline-1,3-dione for Positron-Emission-Tomography Imaging of Phosphodiesterase 10A in the Brain
36. Automated Synthesis of (rac)‐, (R)‐, and (S)‐[18F]Epifluorohydrin and Their Application for Developing PET Radiotracers Containing a 3‐[18F]Fluoro‐2‐hydroxypropyl Moiety
37. Scandium Triflate-Catalyzed N‑[18F]Fluoroalkylation of Aryl- Or Heteroaryl-Amines with [18F]Epifluorohydrin under Mild Conditions.
38. Automated radiosynthesis of [11C]MTP38—a phosphodiesterase 7 imaging tracer—using [11C]hydrogen cyanide for clinical applications.
39. Formation of lamellar structure by competition in crystallization of both components for crystalline–crystalline block copolymers
40. 1つの反応容器を用いた[18F]フルオロエチル化合成法の確立―[18F]FEDAC及び[18F]FET合成について
41. 承認申請を見据えた[64Cu]Cu-ATSM注射液の品質検査法の設定
42. Additional file 1: of Radiosynthesis and in vivo evaluation of 11C-labeled BMS-193885 and its desmethyl analog as PET tracers for neuropeptide Y1 receptors
43. P-114 - Demonstration of intracellular pH-weighting PET imaging using a new-type PET probe responsible for monoacylglycerol lipase activity in the brain
44. In vivo characterizations of [11C]BMS193885 and [11C]Desmethyl-BMS193885 as a PET tracer for neuropeptide Y Y1 receptors
45. Radiosynthesis and quality control testing of the tau imaging positron emission tomography tracer [18F]PM‐PBB3 for clinical applications.
46. Synthesis and evaluation of a new 11C-labeled growth hormone secretagogue receptor 1a probe
47. Simple method for introduction of 3-[18F]fluoro-2-hydroxypropyl group and application for synthesis of 18F-labeled ligand
48. Automated Synthesis of (rac )-, (R )-, and (S )-[18 F]Epifluorohydrin and Their Application for Developing PET Radiotracers Containing a 3-[18 F]Fluoro-2-hydroxypropyl Moiety
49. Synthesis of two novel [18F]fluorobenzene-containing radiotracers via spirocyclic iodonium ylides and positron emission tomography imaging of translocator protein (18 kDa) in ischemic brain
50. Comparison between [ 18 F]fluorination and [ 18 F]fluoroethylation reactions for the synthesis of the PDE10A PET radiotracer [ 18 F]MNI-659
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