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302 results on '"Ohi Y"'

3. 180P Development of prognosis prediction model using cytokeratin 19 mRNA copy number of sentinel lymph node metastasis in breast cancer: A multicenter study in Japan

Author

Yotsumoto, D., primary, Osako, T., additional, Matsuura, M., additional, Takayama, S., additional, Kaneko, K., additional, Takahashi, M., additional, Shimazu, K., additional, Yoshidome, K., additional, Kuraoka, K., additional, Itakura, M., additional, Tani, M., additional, Ishikawa, T., additional, Ohi, Y., additional, Kinoshita, T., additional, Sato, N., additional, Tsujimoto, M., additional, Tsuda, H., additional, Nakamura, S., additional, Noguchi, S., additional, and Akiyama, F., additional

Published
2020
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7. Effectiveness of Neo-Adjuvant Systemic Therapy for Basal HER2 type Breast Cancer – Results from Retrospective Cohort Study of Japan Breast Cancer Research Group (JBCRG) – C03

Author

Ohtani, S., primary, Yasuaki, S., additional, Takada, M., additional, Ohi, Y., additional, Kurozumi, S., additional, Inoue, K., additional, Kosaka, Y., additional, Hattori, M., additional, Yamashita, T., additional, Takao, S., additional, Sato, N., additional, Iwata, H., additional, Kurosumi, M., additional, and Toi, M., additional

Published
2018
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9. Abstract P4-21-25: The importance of hormone receptor status on biomarker expression and the efficacy of lapatinib plus capecitabine therapy after progression on trastuzumab in HER2 positive recurrent and advanced breast cancer

Author

Arima, N, primary, Nishimura, R, additional, Toh, U, additional, Tanaka, M, additional, Saimura, M, additional, Okumura, Y, additional, Saito, T, additional, Tanaka, T, additional, Teraoka, M, additional, Shimada, K, additional, Koga, T, additional, Kurashita, K, additional, Todoroki, H, additional, Ueo, H, additional, Ohi, Y, additional, Toyoshima, S, additional, Mitsuyama, S, additional, and Tamura, K, additional

Published
2017
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16. Observations of solar energetic particles at a synchronous orbit

Author

Takenaka, T, Ohi, Y, Yanagimachi, T, Ito, K, Kohno, T, and Sakurai, K

Subjects
Solar Physics
Abstract

The Space Environment Monitors (SEM) on board the Japanese geostationary meteorological satellites (GMS-1 and GMS-2) observed energetic protons, alpha particles and electrons continuously for February 1978 to September 1984. The satellites were at 6.6 Earth radii above 140 deg E equator.

Published
1985

17. Human papillomavirus detected in female breast carcinomas in Japan

Author

Khan, N A, primary, Castillo, A, additional, Koriyama, C, additional, Kijima, Y, additional, Umekita, Y, additional, Ohi, Y, additional, Higashi, M, additional, Sagara, Y, additional, Yoshinaka, H, additional, Tsuji, T, additional, Natsugoe, S, additional, Douchi, T, additional, Eizuru, Y, additional, and Akiba, S, additional

Published
2008
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34. Inhibition of spontaneous excitatory transmission induced by codeine is independent on presynaptic K+ channels and novel voltage-dependent Ca2+ channels in the guinea-pig nucleus tractus solitarius

Author

Haji, A. and Ohi, Y.

Subjects
*SOLITARY nucleus, *CODEINE, *BRAIN stem, *POTASSIUM channels, *LABORATORY swine, *NEURAL transmission, *TETRODOTOXIN, *AMINOPYRIDINES, *CEREBROSPINAL fluid
Abstract

Abstract: The nucleus tractus solitarius (NTS) constitutes the cough reflex arc and is thought to be one of the main sites of codeine''s action. We have previously demonstrated using the guinea-pig brainstem slice that codeine inhibits the solitary tract-evoked excitatory postsynaptic currents (EPSCs) in the second-order NTS neurons through activating the presynaptic K+ channels. For further understanding of modulation of synaptic transmission by the antitussive, the effects of codeine (0.3–3.0 mM) on spontaneous EPSCs (sEPSCs) and miniature EPSCs (mEPSCs) were investigated in the NTS neurons of guinea-pigs. Codeine decreased the frequency and amplitude of sEPSCs. This action of codeine was mimicked by specific μ and κ receptor agonists, and blocked by μ and κ receptor antagonists. An agonist of δ receptors was ineffective on sEPSCs. The inhibitory effect of codeine on sEPSCs persisted under perfusion of a K+ channel blocker, 4-aminopyridine. In the presence of tetrodotoxin or Cd2+ which blocks, respectively, the action potential-induced or voltage-dependent Ca2+ entry-induced transmitter release, codeine still had an inhibitory effect on the frequency of mEPSCs without any considerable effect on their amplitude. The present study demonstrates that codeine depresses spontaneous excitatory synaptic transmission in the NTS neurons via presynaptic μ and κ receptors that do not couple with K+ and Ca2+ channels. These results suggest inhibitory modulation of the local circuit activity of NTS neurons by codeine, resulting in suppression of cough reflex. [Copyright &y& Elsevier]

Published
2010
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35. Ryanodine receptor/Ca2+ release mechanisms in rhythmically active respiratory neurons of cats in vivo

Author

Haji, A. and Ohi, Y.

Subjects
*RYANODINE receptors, *NEURAL physiology, *PROTEIN kinases, *NEUROSCIENCES
Abstract

Abstract: The cytosolic Ca2+ released from internal stores is important for distinctive cell functions. To assess the role of ryanodine/Ca2+ releasing mechanisms in the rhythmic activity of respiratory neurons, effects of intracellular injection of ryanodine on the membrane potential trajectory of postinspiratory and augmenting inspiratory neurons were investigated in unanesthetized, decerebrate, paralyzed and artificially ventilated cats. Ryanodine injection hyperpolarized the membrane and decreased input resistance throughout the respiratory cycle in both types of respiratory neurons. Specifically, membrane repolarization during postinspiration was accelerated in postinspiratory neurons, and the large hyperpolarization at the onset of postinspiration was increased in augmenting inspiratory neurons. Spike-afterhyperpolarization consisting of a fast, early component and slow, late component increased in size after ryanodine, resulting in prolongation of inter-spike intervals and decrease of burst discharge. Intracellular injection of caffeine produced similar effects on these respiratory neurons, and Ruthenium Red, an antagonist of ryanodine receptors, had opposite effects. Immunoreactivity for ryanodine receptors was detected in all respiratory neurons labeled intracellularly with neurobiotin. These results demonstrate that ryanodine-sensitive Ca2+ stores modulate the periodic membrane potential fluctuations and spike activity in respiratory neurons. [Copyright &y& Elsevier]

Published
2006
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36. From Necessity to Choice: Social Change in Norway 1930-1980.

Author

Rams&ohi;y, Natalie Rogoff

Subjects
*SOCIAL change, *WORLD War I, *ECONOMISTS, *SOCIAL history, *ECONOMIC history
Abstract

The article comments on social change in Norway during 1930-1980. A major difficulty arises in tracing social change over a given historical period. People must step into history at what will inevitably be an arbitrary point in time in the sense that conditions at the beginning of a period inevitably will be colored by what went on before. This is particularly striking in the case of Norway in and around 1930. The years corresponding to the First World War represented an economic boom in Norway, since its exports were in great demand by the warring nations. But the bubble burst in 1920 and from then until well into the 1930s, the economy went into a decline. During the late 1920s and 1930s, Norway experienced a return to the primary sector, after an earlier period during which industry and services had grown at the expense of the primary sector. Here it is important to distinguish between what the figures used by economists in their construction of economic history show, and what people learn by looking at information concerning individuals and households. The growth in the Norwegian economy, when measured in monetary units, continued to take place in industry and services, but the primary sector did not lose population to the rest of the economy in a corresponding fashion.

Published
1986

37. The binding site for fucose-binding proteins of Lotus tetragonolobus is a prognostic marker for transitional cell carcinoma of the human urinary bladder.

Author

Shirahama, Tsutomu, Ikoma, Michiaki, Muramatsu, Takashi, Kayajima, Tsuneyoshi, Ohi, Yoshitada, Tsushima, Tomoyasu, Akebi, Naoki, Ohmori, Hiroyuki, Hirao, Yoshihiko, Okajima, Eigorou, Shirahama, T, Ikoma, M, Muramatsu, T, Kayajima, T, Ohi, Y, Tsushima, T, Akebi, N, Ohmori, H, Hirao, Y, and Okajima, E

Published
1993
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42. Goserelin acetate with or without antiandrogen or estrogen in the treatment of patients with advanced prostate cancer: a multicenter, randomized, controlled trial in Japan. Zoladex Study Group.

Author

Kotake, T, Usami, M, Akaza, H, Koiso, K, Homma, Y, Kawabe, K, Aso, Y, Orikasa, S, Shimazaki, J, Isaka, S, Yoshida, O, Hirao, Y, Okajima, E, Naito, S, Kumazawa, J, Kanetake, H, Saito, Y, Ohi, Y, and Ohashi, Y

Abstract

The aims of this randomized, controlled study were to investigate the efficacy and safety of long-term monotherapy with the luteinizing hormone-releasing hormone agonist goserelin acetate compared with both short- and long-term combined androgen blockade.

Published
1999
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46. A new dynamical approach to auditory evoked magnetic field by blind identification

Author

Kishida K, Ohi Y, Mitsuo Tonoike, and Iwaki S

Subjects
Acoustic Stimulation, Statistics as Topic, Evoked Potentials, Auditory, Humans, Magnetoencephalography
Abstract

A new approach to understand neural dynamics underlying the generation of auditory evoked magnetic field is proposed. MEG time series data are temporally decorrelated by using a blind signal separation method. Two components are selected from their periodical property and a remixing matrix is applied to the two selected components to retrieve MEG signals of auditory evoked magnetic field. After principal component data for each sensor pairs are calculated, a minimum phase innovation model is identified from the viewpoint of statistical inverse problem. By using a blind identification method based on feedback system theory transfer functions can be evaluated to get a dynamical understanding of brain auditory functions. It is reported that all changes of their impulse responses between right and left hemisphere decay within about 40 ms, and that directional differences in transfer functions can be found.

47. Clinical Evaluation of Urethral Tumors Based on a Simple Classification System

Author

Akaza, H., primary, Homma, Y., additional, Koiso, K., additional, Yoshida, O., additional, Suzuki, K., additional, Hisazumi, H., additional, Tsugawa, R., additional, Matsumoto, K., additional, Kawai, T., additional, Nagayama, T., additional, Obata, K., additional, Sonoda, T., additional, Kotake, T., additional, Okajima, E., additional, Matsumura, Y., additional, Kumazawa, J., additional, Ohi, Y., additional, Ogata, J., additional, Uyama, K., additional, Maru, A., additional, Machida, T., additional, Tazaki, H., additional, Satomi, Y., additional, Aso, Y., additional, and Niijima, T., additional

Published
1988
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