205 results on '"Ohgaki, Ryuichi"'
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2. LAT1 expression in colorectal cancer cells is unresponsive to HIF-1/2α accumulation under experimental hypoxia
3. Structure–activity characteristics of phenylalanine analogs selectively transported by L-type amino acid transporter 1 (LAT1)
4. Upregulation of ATF4 mediates the cellular adaptation to pharmacologic inhibition of amino acid transporter LAT1 in pancreatic ductal adenocarcinoma cells
5. Identification of tumor-suppressive miRNAs that target amino acid transporter LAT1 and exhibit anti-proliferative effects on cholangiocarcinoma cells
6. Inhibition of amino acid transporter LAT1 in cancer cells suppresses G0/G1-S transition by downregulating cyclin D1 via p38 MAPK activation
7. LAT1 expression influences Paneth cell number and tumor development in ApcMin/+ mice
8. Inhibition of cancer-type amino acid transporter LAT1 suppresses B16-F10 melanoma metastasis in mouse models
9. Evaluation of LAT1 Expression in Patients With Lung Cancer and Mediastinal Tumors: 18F-FBPA PET Study With Immunohistological Comparison
10. Functional coupling of organic anion transporter OAT10 (SLC22A13) and monocarboxylate transporter MCT1 (SLC16A1) influencing the transport function of OAT10
11. Structural insights into inhibitory mechanism of human excitatory amino acid transporter EAAT2
12. Phosphoproteomics revealed cellular signals immediately responding to disruption of cancer amino acid homeostasis induced by inhibition of l-type amino acid transporter 1
13. Correction: LAT1 expression influences Paneth cell number and tumor development in ApcMin/+ mice
14. Boron delivery for boron neutron capture therapy targeting a cancer-upregulated oligopeptide transporter
15. Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc
16. The Clinical Potential of FBPA-PET/CT Imaging for Colorectal Cancer and its Liver Metastases Expressing LAT1
17. Structure-activity relationship of a novel series of inhibitors for cancer type transporter L-type amino acid transporter 1 (LAT1)
18. Impaired Amino Acid Transport at the Blood Brain Barrier Is a Cause of Autism Spectrum Disorder
19. Transport of 3-fluoro-l-α-methyl-tyrosine (FAMT) by organic ion transporters explains renal background in [18F]FAMT positron emission tomography
20. Novel cystine transporter in renal proximal tubule identified as a missing partner of cystinuria-related plasma membrane protein rBAT/SLC3A1
21. Functional coupling with endogenous monocarboxylic acid transporter MCT1 influences on transport function of exogenously expressed organic anion transporter OAT10 in HEK293 cells: a warning on transporter assays
22. 低酸素誘導因子の蓄積が大腸がん細胞におけるアミノ酸トランスポーターLAT1の発現に与える影響
23. Mechanisms of the inhibition of cancer cell proliferation by LAT1 inhibitors revealed by the changes in the intracellular concentrations and function of individual amino acids
24. Structure–activity relations of leucine derivatives reveal critical moieties for cellular uptake and activation of mTORC1-mediated signaling
25. Pharmacologic inhibition of LAT1 predominantly suppresses transport of large neutral amino acids and downregulates global translation in cancer cells
26. Combination effects of amino acid transporter LAT1 inhibitor nanvuranlat and cytotoxic anticancer drug gemcitabine on pancreatic and biliary tract cancer cells.
27. LAT1 expression influences Paneth cell number and tumor development in ApcMin/+ mice.
28. Linkage of N-cadherin to multiple cytoskeletal elements revealed by a proteomic approach in hippocampal neurons
29. Establishment of Stable Cell Lines With High Expression of Heterodimers of Human 4F2hc and Human Amino Acid Transporter LAT1 or LAT2 and Delineation of Their Differential Interaction With α-Alkyl Moieties
30. Additional file 1 of Phosphoproteomics revealed cellular signals immediately responding to disruption of cancer amino acid homeostasis induced by inhibition of l-type amino acid transporter 1
31. Amino acid transporter LAT1 (SLC7A5) on cancer cell-derived exosomes as a potential prognostic- and diagnostic biomarker.
32. Inhibition of amino acid transporter LAT1 drastically suppresses the transport of large neutral amino acids and induces the downregulation of global translation in cancer cells
33. Contribution of LAT1 to amino acid uptake in cancer cells and suppression of cellular protein synthesis by LAT1 inhibitor
34. Structural insights into human excitatory amino acid transporter EAAT2
35. Boronophenylalanine, a boron delivery agent for boron neutron capture therapy, is transported by ATB0,+, LAT1 and LAT2
36. Cell Surface Levels of Organellar Na+/H+ Exchanger Isoform 6 Are Regulated by Interaction with RACK1
37. A Membrane-Proximal Region in the C-Terminal Tail of NHE7 Is Required for Its Distribution in the Trans-Golgi Network, Distinct from NHE6 Localization at Endosomes
38. FC 014INFLUENCE OF GENETIC VARIATION IN SLC7A13/AGT1 IN HUMAN CYSTINURIA
39. Correction: A novel mutation in the SLCO2A1 gene, encoding a prostaglandin transporter, induces chronic enteropathy
40. Nicotine induces dendritic spine remodeling in cultured hippocampal neurons
41. Amino acid transporter LAT1 is upregulated in tumor-associated vascular endothelial cells and plays essential roles in tumor angiogenesis by promoting proliferation and regulating VEGF-A-dependent pro-angiogenic mTORC1 activation.
42. Proteomics and phosphoproteomics reveal key regulators associated with cytostatic effect of amino acid transporter LAT1 inhibitor
43. Amino acid transporter LAT1 in tumor-associated vascular endothelium promotes angiogenesis by regulating cell proliferation and VEGF-A-dependent mTORC1 activation
44. A novel mutation in the SLCO2A1 gene, encoding a prostaglandin transporter, induces chronic enteropathy
45. Interaction of Halogenated Tyrosine/Phenylalanine Derivatives with Organic Anion Transporter 1 in the Renal Handling of Tumor Imaging Probes
46. Characterization of the ion transport activity of the budding yeast Na +/H + antiporter, Nha1p, using isolated secretory vesicles
47. Additional file 1 of Amino acid transporter LAT1 in tumor-associated vascular endothelium promotes angiogenesis by regulating cell proliferation and VEGF-A-dependent mTORC1 activation
48. Critical moieties of aromatic amino acid probes causing renal accumulation in tumor imaging
49. Suppression of LAT1 in endothelial cells of tumor tissues exhibits an anti-angiogenesis effect
50. Time-course analysis of the changes in intracellular amino acid concentrations and amino acid-related signaling pathways in cancer cells induced by the inhibition of cancer-type amino acid transporter LAT1
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