Search

Your search keyword '"Ohga, Takefumi"' showing total 222 results
Start Over Author "Ohga, Takefumi"
222 results on '"Ohga, Takefumi"'

5. New technique for the retraction of the liver in laparoscopic gastrectomy

Author

Sakaguchi, Yoshihisa, Ikeda, Osamu, Toh, Yasushi, Aoki, Yoshiro, Harimoto, Norifumi, Taomoto, Junya, Masuda, Takaaki, Ohga, Takefumi, Adachi, Eisuke, and Okamura, Takeshi

Abstract

Abstract: We developed a new technique for the retraction of the liver using a Penrose drain and a J-shaped retractor, which is both an easy and time-saving method that provides a good view during laparoscopic gastrectomy without damaging the liver.

Published
2024
Full Text
View/download PDF

8. Spindle cell carcinoma of the breast : A case report

Author

Nozoe, Emiko, Nozoe, Tadahiro, Tanaka, Junko, Ohga, Takefumi, Fujita, Aya, and Sueishi, Katsuo

Subjects
malignant potential, spindle cell carcinoma, skin and connective tissue diseases, breast
Abstract

Spindle cell carcinoma (SpCC) of the breast is quite a rare modality classified to the metaplastic carcinoma of the breast. Regarding its biological behavior and the prognosis of the patients with this rare tumor, it has been remaining controversial. We herein report an 88 year-old woman who had a huge bleeding tumor on the right breast. She was a high-aged woman with low activities of daily life, even with some suspicion of distant organ metastasis. While the tumor proved to drastically bleed due to the tumor disintegration, a right simple mastectomy was performed. According to the histopathologic examinations, sarcomatoid spindle cells with severe atypia were observed. By an immunohistochemical examination, the tumor had proved to express neither estrogen receptor, progesterone receptor nor HER2 receptor. Moreover an immunohistochemical expression of AE1/3 and CAM5.2, defining an epithelial neoplasm were observed in addition to an expression of vimentin. From these findings, this bleeding tumor was diagnosed as spindle cell carcinoma of the breast.

Published
2020

13. A multicenter phase II clinical study of oxaliplatin, folinic acid, and 5-fluorouracil combination chemotherapy as first-line treatment for advanced colorectal cancer: A Japanese experience

Author

Baba, Hideo, Hayashi, Naoko, Emi, Yasunori, Kakeji, Yoshihiro, Egashira, Akinori, Oki, Eiji, Shirabe, Ken, Toyama, Tetsuo, Ohga, Takefumi, Yamamoto, Manabu, Hasegawa, Hirofumi, Kohakura, Fumiko, Higashi, Hidefumi, Niwa, Kiyoshi, Fujita, Fumihiko, Ogata, Yutaka, Kohnoe, Shunji, Inomata, Masafumi, Samura, Hironori, Tokunaga, Shoji, Maehara, Yoshihiko, and Kyushu Study Group of Clinical Cancer (KSCC)

Published
2011
Full Text
View/download PDF

26. A case of adenoid cystic carcinoma of the breast

Author

Nozoe, Tadahiro, Nozoe, Emiko, Ohga, Takefumi, Ezaki, Takahiro, and Sueishi, Katsuo

Subjects
breast cancer, adenoid cystic carcinoma, skin and connective tissue diseases, pulmonary metastasis
Abstract

An 85-year old woman who had a large tumor in the left breast came to our out-patient clinic. Computed tomography showed multiple lung tumors in addition to a huge tumor in the left breast. A needle biopsy brought about a histological diagnosis of ductal carcinoma. A simple mastectomy was performed and a histological examination using the resected specimen demonstrated a coexistence of an adenoid structure and a false ductal structure according the histologic characteristics of adenoid cystic carcinoma, which is quite rare among breast tumors.

Published
2018

28. New scoring system to create a prognostic criteria in colorectal carcinoma based on serum elevation of C-reactive protein and decrease in lymphocyte in peripheral blood

Author

Nozoe, Tadahiro, Kono, Mayuko, Kuma, Sosei, Tsujita, Eiji, Ohga, Takefumi, Nozoe, Tadahiro, Kono, Mayuko, Kuma, Sosei, Tsujita, Eiji, and Ohga, Takefumi

Abstract

BACKGROUND. Both serum elevation of C-reactive protein (CRP) and reduction of lymphocyte in the peripheral blood has been known as indicator for malignant potential of human tumors. METHODS. Whether newly devised CLS (CRP/Lymphocyte Score), based on combined data of serum elevation of CRP and of lymphocyte percentage in the peripheral blood can be an indicator for progressive potential in colorectal carcinoma was examined in 280 cases who had been surgically treated. RESULTS. Significant difference in survival was observed both between CLS 0 and 1 and between CLS 1 and 2, in both cases when analyzed among whole patients and patient who had been treated with curative resection. Multivariate analysis among patients who had been treated with curative resection demonstrated that CLS (P < 0.0001), histologic type (P = 0.0003), and tumor stage (P = 0.039) were factors independently associated with worse prognosis of the patients. CONCLUSIONS. Newly devised criteria CLS could be an independent prognostic indicator in colorectal carcinoma and would be utilized as a helpful information.

Published
2019

40. Definition of Prognosis Based on Lymph Node Metastasis and Elevation of Serum C-Reactive Protein for Patients with Gastric Carcinoma Treated with Curative Resection

Author

Nozoe, Tadahiro, Kono, Mayuko, Hashimoto, Naotaka, Tsujita, Eiji, Kuma, Sosei, Ohga, Takefumi, Nozoe, Tadahiro, Kono, Mayuko, Hashimoto, Naotaka, Tsujita, Eiji, Kuma, Sosei, and Ohga, Takefumi

Abstract

Purpose. The aim of this study was to develop prognostic criteria based on the combination of nodal metastasis and preoperative elevation of serum C-reactive protein (CRP) for patients with gastric carcinoma that have been treated with curative resection. Methods. Three hundred and twenty patients with gastric carcinoma who had been treated with curative resection were enrolled. One point was provided for each incidence of nodal metastasis and preoperative elevation of serum CRP and we examined whether this cumulative score system could provide a strict stratification of survival. Results. Significant differences regarding survival were observed both between patients with scores of 0 and 1 (P < 0.0001) and between patients with scores of 1 and 2 (P < 0.0001). Multivariate analysis showed that the cumulative score (P = 0.0003) and the depth of the tumor (P = 0.016) were independent prognostic indicators. Conclusions. Criteria for the prediction of prognosis in gastric carcinoma treated with curative resection based on tumor-related and host-related factors could provide a strict stratification.

Published
2018

42. Pancreatic cancer arising from the remnant pancreas after pancreatectomy: a multicenter retrospective study by the Kyushu Study Group of Clinical Cancer

Author

Hashimoto, Daisuke, primary, Arima, Kota, additional, Nakagawa, Shigeki, additional, Negoro, Yuji, additional, Hirata, Toshihiko, additional, Hirota, Masahiko, additional, Inomata, Masafumi, additional, Fukuzawa, Kengo, additional, Ohga, Takefumi, additional, Saeki, Hiroshi, additional, Oki, Eiji, additional, Yamashita, Yo-ichi, additional, Chikamoto, Akira, additional, Baba, Hideo, additional, and Maehara, Yoshihiko, additional

Published
2018
Full Text
View/download PDF

47. Further evidence to demonstrate the significance of serum appearance of anti-p53 antibody as a marker for progressive potential in invasive ductal carcinoma of the breast

Author

Nozoe, Tadahiro, Nozoe, Emiko, Kono, Mayuko, Ohga, Takefumi, Ezaki, Takahiro, Nozoe, Tadahiro, Nozoe, Emiko, Kono, Mayuko, Ohga, Takefumi, and Ezaki, Takahiro

Abstract

Background : Serum appearance of anti-p53 antibody (p53Ab) has been reported as an indicator for progressive potential of human tumor tumors including breast cancer. But its significance in breast cancer has not been discussed fully.Methods : Relationship between serumappearance of p53Abs and representative data accounting for progressive potential in breast cancer, nuclear grade (NG), triple negative cancer, and the cumulative score based on these two data (TGS) was investigated among 129 women with invasive ductal carcinoma (IDC) of the breast, who had been treated with surgical resection. Results : There was a significant correlation between appearance of p53Abs and recurrence of the tumors (P = 0.035). Significant correlation of serum appearance of p53Abs with negative expression of ER (P = 0.011), the proportion of TNBC (P = 0.013), NG (P = 0.017), and TGS (P = 0.0005). Conclusions : Preoperative serum appearance of p53Abs can be correlated with pathological nuclear grade, incidence of triple negative breast cancer, and TGS. These resultsmight demonstrate more powerful significance of serum appearance of p53Abs as an indicator of progressive potential in IDC of the breast.

Published
2017

50. Impact of high preoperative steroid doses on postoperative complications among patients on prolonged preoperative steroid therapy

Author

Iguchi, Tomohiro, Shirabe, Ken, Inoue, Kentaro, Ito, Shuhei, Ohga, Takefumi, Nozoe, Tadahiro, Ezaki, Takahiro, Yoshizumi, Tomoharu, Uchiyama, Hideaki, Soejima, Yuji, Ikegami, Toru, Yamashita, Yo-ichi, Kawanaka, Hirofumi, Ikeda, Tetsuo, Saeki, Hiroshi, Morita, Masaru, and Maehara, Yoshihiko

Subjects
Aged, 80 and over, Male, Time Factors, Dose-Response Relationship, Drug, Hydrocortisone, Anti-Inflammatory Agents, Anesthesia, General, Middle Aged, Severity of Illness Index, Postoperative Complications, Surgical Procedures, Operative, Preoperative Care, Humans, Female, Morbidity, Steroid, Complication, Aged
Abstract

Corticosteroids are essential to maintain the organic homeostasis. Steroid, glucocorticoid or its synthetic analog is widely used for inflammatory and autoimmune diseases. Prolonged steroid therapy is reported to cause the susceptibility to infection, impaired wound healing and psychoneurosis, however whether the quantity of taking the preoperative steroid is associated the postoperative complication is still unknown. The aim of this study was to elucidate whether the steroid dose in patients on prolonged preoperative steroid therapy is associated postoperative morbidity and mortality. Twenty-five patients taking steroid for various illnesses and underwent the surgery under general anesthesia were selected in this study. The mean ± standard deviation and the median of the steroid dose converted into hydrocortisone (mg/day) were 39.2 ± 31.0 and 20, respectively. Of 25 cases, postoperative complications were seen in 10 cases. The postoperative complication was severe based on the grade of Clavien and Dindo by ANOVA as the doses of taking steroid increased (p = 0.0171). The grave postoperative complication classified as Clavien and Dindo grade III occurred with 100% sensitivity and 87% specificity for the steroid dose converted into hydrocortisone > 80mg/day. Preoperative taking the large amount of steroid (> 80mg/day) could cause a grave complication. More careful selection of the operative procedure might improve the mobidity rate., コルチコステロイドは生体の恒常性を維持するのに必須なホルモンである．グルココルチコイドやその合成アナログであるステロイドは炎症性疾患や自己免疫性疾患に対して広く使用されている．長期間のステロイド治療により易感染，創傷治癒遷延，精神症状を引き起こすと報告されているが，術前のステロイド内服量と術後合併症との関連については言及されていない．種々の疾患に対し長期間ステロイド治療が行われ，全身麻酔下に外科手術を施行された25例を対象とした．ヒドロコルチゾンに換算したステロイド内服量(mg/day)の平均±標準偏差および中央値はそれぞれ39.2 ± 31.0，20であった．25例中10例に術後合併症を認めた．ステロイド内服量とClavien-Dindo分類による術後合併症の重症度は有意に正の相関を示した(p=0.0171)．ヒドロコルチゾンに換算したステロイド内服量のcut-off値を80mg/day以上とした場合のClavien-Dindo分類III度の合併症の発生は感度100%，特異度87%であった．術前ステロイド内服量が80mg/day以上の患者では，術後重篤な合併症を引き起こしうる．より慎重な術式の選択などの工夫が肝要である．

Published
2014

Catalog

Books, media, physical & digital resources
See catalog results