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381 results on '"Ohdaira, Hironori"'

13. Usefulness of the C-Reactive Protein (CRP)-Albumin-Lymphocyte (CALLY) Index as a Prognostic Indicator for Patients With Gastric Cancer

Author

Nakashima, Keigo, Haruki, Koichiro, Kamada, Teppei, Takahashi, Junji, Tsunematsu, Masashi, Ohdaira, Hironori, Furukawa, Kenei, Suzuki, Yutaka, and Ikegami, Toru

Abstract

Background The C-reactive protein (CRP)-albumin-lymphocyte (CALLY) index is a novel immune nutrition scoring system associated with cancer prognosis. This study investigated the association between the CALLY index and the long-term outcomes of patients with gastric cancer.Methods We included 175 patients with gastric cancer who underwent curative gastrectomies at the Department of Surgery, International University of Health and Welfare Hospital between January 2011 and October 2019. The CALLY index was calculated based on the levels of serum albumin, serum CRP, and peripheral lymphocyte count. Utilizing both univariate and multivariate analyses, the prognostic value of the CALLY index was investigated.Results In the multivariate analyses, disease stage (hazard ratio [HR], 7.85; 95% confidence interval [CI], 3.31-18.6; P< .01), microvascular invasion (HR, 2.88; 95% CI, 1.30-6.36; P< .01), and low CALLY index (HR, 2.18; 95% CI, 1.00-4.76; P= .05) were independent and significant predictors of disease-free survival. Low body mass index (HR, 4.15; 95% CI, 1.63-10.6; P< .01), advanced disease stage (HR, 8.22; 95% CI, 3.47-19.5; P< .01), and low CALLY index (HR, 3.00; 95% CI, 1.3-6.93; P= .01) were independent and significant predictors of overall survival. The low CALLY index group had a lower body mass index (P< .01), advanced disease stage (P< .01), and a higher Glasgow prognostic score (P< .01).Conclusions The CALLY index may be associated with a poor prognosis for gastric cancer, highlighting the utility of a comprehensive assessment using inflammatory, nutritional, and immunological statuses.

Published
2024
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32. Interaction of Vitamin D Supplements and Marine n -3 Fatty Acids on Digestive Tract Cancer Prognosis.

Author

Fukuzato, Soichiro, Ohdaira, Hironori, Suzuki, Yutaka, and Urashima, Mitsuyoshi

Abstract

A meta-analysis suggested that marine n-3 polyunsaturated fatty acids (PUFAs), e.g., eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), might reduce cancer mortality. However, a randomized clinical trial of marine n-3 PUFA and vitamin D supplementation failed to verify this benefit. This study aimed to investigate the potential interaction between vitamin D supplementation and serum EPA and DHA levels. This post hoc analysis of the AMATERASU trial (UMIN000001977), a randomized controlled trial (RCT), included 302 patients with digestive tract cancers divided into two subgroups stratified by median serum levels of EPA + DHA into higher and lower halves. The 5-year relapse-free survival (RFS) rate was significantly higher in the higher half (80.9%) than the lower half (67.8%; hazard ratio (HR), 2.15; 95% CI, 1.29–3.59). In the patients in the lower EPA + DHA group, the 5-year RFS was significantly higher in the vitamin D (74.9%) than the placebo group (49.9%; HR, 0.43; 95% CI, 0.24–0.78). Conversely, vitamin D had no effect in the higher half, suggesting that vitamin D supplementation only had a significant interactive effect on RFS in the lower half (p for interaction = 0.03). These results suggest that vitamin D supplementation may reduce the risk of relapse or death by interacting with marine n-3 PUFAs. [ABSTRACT FROM AUTHOR]

Published
2024
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33. Primary small‐cell carcinoma in the lung was found after the cold snare polypectomy of the small metastatic lesion in the cecum: A case report

Author

Suto, Daisuke, primary, Yoshida, Masashi, additional, Yamada, Hidehiko, additional, Akita, Takayuki, additional, Osawa, Yosuke, additional, Sato, Kiichi, additional, Otake, Takaaki, additional, Nakazato, Yoshimasa, additional, Arakawa, Nobuhito, additional, Ohdaira, Hironori, additional, Suzuki, Yutaka, additional, and Kohgo, Yutaka, additional

Published
2023
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37. A technique for esophagojejunostomy following robot assisted gastrectomy: a liner stapler and barbed suture device based technique: A case series

Author

Ohdaira, Hironori, primary, Kamada, Teppei, additional, Takahashi, Junji, additional, Nakashima, Keigo, additional, Nakaseko, Yuichi, additional, Ishigaki, Takayuki, additional, Suzuki, Norihiko, additional, Yoshida, Masashi, additional, Yamanouchi, Eigoro, additional, and Suzuki, Yutaka, additional

Published
2023
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42. Real‐time vessel navigation using indocyanine green fluorescence during robotic‐assisted gastrectomy for gastric cancer after coronary artery bypass grafting using the right gastroepiploic artery

Author

Kamada, Teppei, primary, Ohdaira, Hironori, additional, Nakashima, Keigo, additional, Nishide, Ryo, additional, Nishie, Ryosuke, additional, Takahashi, Junji, additional, Ito, Eisaku, additional, Nakaseko, Yuichi, additional, Suzuki, Norihiko, additional, Yoshida, Masahi, additional, Sumi, Makoto, additional, and Suzuki, Yutaka, additional

Published
2023
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48. Risk factors for refractory enterocutaneous fistula following button jejunostomy removal and its treatment using a novel extraperitoneal approach in patients with esophageal cancer: A retrospective cohort study

Author

Kamada, Teppei, primary, Ohdaira, Hironori, additional, Nakashima, Keigo, additional, Nishide, Ryo, additional, Takahashi, Junji, additional, Ito, Eisaku, additional, Nakaseko, Yuichi, additional, Suzuki, Norihiko, additional, Yoshida, Masashi, additional, Eto, Ken, additional, and Suzuki, Yutaka, additional

Published
2022
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