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4. Burden and outcomes of postpartum haemorrhage in Nigerian referral‐level hospitals

Author

Adebayo, Tajudeen, primary, Adefemi, Ayodeji, additional, Adewumi, Idowu, additional, Akinajo, Opeyemi, additional, Akinkunmi, Bola, additional, Awonuga, David, additional, Aworinde, Olufemi, additional, Ayegbusi, Ekundayo, additional, Dedeke, Iyabode, additional, Fajolu, Iretiola, additional, Imam, Zainab, additional, Jagun, Olusoji, additional, Kuku, Olumide, additional, Ogundare, Ezra, additional, Oluwasola, Timothy, additional, Oyeneyin, Lawal, additional, Adebanjo‐Aina, Damilola, additional, Adenuga, Emmanuel, additional, Adeyanju, Alaruru, additional, Akinsanya, Olufemi, additional, Campbell, Ibijoke, additional, Kuti, Bankole, additional, Olofinbiyi, Babatunde, additional, Salau, Qasim, additional, Tongo, Olukemi, additional, Ezekwe, Bosede, additional, Lavin, Tina, additional, Oladapo, Olufemi T., additional, Tukur, Jamilu, additional, and Adesina, Olubukola, additional

Published
2024
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5. Determinants and outcomes of preterm births in Nigerian tertiary facilities.

Author

Fajolu, Iretiola Bamikeolu, Dedeke, Iyabode Olabisis Florence, Oluwasola, Timothy A., Oyeneyin, Lawal, Imam, Zainab, Ogundare, Ezra, Campbell, Ibijoke, Akinkunmi, Bola, Ayegbusi, Ekundayo O., Agelebe, Efeturi, Adefemi, Ayodeji K., Awonuga, David, Jagun, Olusoji, Salau, Qasim, Kuti, Bankole, Tongo, Olukemi Oluwatoyin, Adebayo, Tajudeen, Adebanjo‐Aina, Damilola, Adenuga, Emmanuel, and Adewumi, Idowu

Subjects
PREMATURE labor, MEDICAL quality control, PRENATAL care, PERINATAL death, MATERNAL age, NEONATAL mortality
Abstract

Objective: To describe the incidence, and sociodemographic and clinical factors associated with preterm birth and perinatal mortality in Nigeria. Design: Secondary analysis of data collected through the Maternal Perinatal Database for Quality, Equity and Dignity (MPD‐4‐QED) Programme. Setting: Data from births in 54 referral‐level hospitals across Nigeria between 1 September 2019 and 31 August 2020. Population: A total of 69 698 births. Methods: Multilevel modelling was used to determine the factors associated with preterm birth and perinatal mortality. Outcome measures: Preterm birth and preterm perinatal mortality. Results: Of 62 383 live births, 9547 were preterm (153 per 1000 live births). Maternal age (<20 years – adjusted odds ratio [aOR] 1.52, 95% CI 1.36–1.71; >35 years – aOR 1.23, 95% CI 1.16–1.30), no formal education (aOR 1.68, 95% CI 1.54–1.84), partner not gainfully employed (aOR 1.94, 95% CI 1.61–2.34) and no antenatal care (aOR 2.62, 95% CI 2.42–2.84) were associated with preterm births. Early neonatal mortality for preterm neonates was 47.2 per 1000 preterm live births (451/9547). Father's occupation (manual labour aOR 1.52, 95% CI 1.20–1.93), hypertensive disorders of pregnancy (aOR 1.37, 95% CI 1.02–1.83), no antenatal care (aOR 2.74, 95% CI 2.04–3.67), earlier gestation (28 to <32 weeks – aOR 2.94, 95% CI 2.15–4.10; 32 to <34 weeks – aOR 1.80, 95% CI 1.3–2.44) and birthweight <1000 g (aOR 21.35, 95% CI 12.54–36.33) were associated with preterm perinatal mortality. Conclusions: Preterm birth and perinatal mortality in Nigeria are high. Efforts should be made to enhance access to quality health care during pregnancy, delivery and the neonatal period, and improve the parental socio‐economic status. [ABSTRACT FROM AUTHOR]

Published
2024
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7. Neonatal Jaundice: Perception of Pregnant Women Attending Antenatal Clinic at a Tertiary Hospital in Southwest, Nigeria

Author

Ogundare Ezra Olatunde, Omoyajowo Adefunke Christianah, Babatola Adefunke Olarinre, Ajite Adebukola Bidemi, Adeniyi Adewuyi Temidayo, Fatunla Odunayo Adebukola, Agaja Oyinkansola Tolulope, Taiwo Adekunle Bamidele, Oluwayemi Isaac Oludare, and Olatunya Oladele Simeon

Subjects
Pediatrics, RJ1-570
Abstract

Background: Severe neonatal jaundice (NNJ) remains a leading cause of preventable brain damage, mental handicap, physical disabilities, and early death among infants. Methods : Using a descriptive cross-sectional study design, information was gathered using a structured, pretested questionnaire from 518 pregnant women who attended the antenatal clinic at a tertiary Hospital in Southwest Nigeria. Results : Most (77%) of the respondents have heard about NNJ prior the survey. Most respondents (69.5%) demonstrated poor knowledge of the causes of NNJ. The majority, 98.4% had good attitude toward treatment of NNJ. Most respondents (72.1%) demonstrated poor knowledge of the correct treatment of NNJ. A quarter of the respondents knew no danger sign of NNJ. Conclusion : There is serious knowledge gap among the respondents about the causes, treatment, dangers signs and complications of NNJ. There is need for increased awareness campaign using every available means of reaching women of reproductive age group to reduce the consequences of this common neonatal problem.

Published
2020
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9. Human milk banking acceptability among pregnant and nursing mothers in Southwest Nigeria

Author

Ogundare, Ezra Olatunde, primary, Dedeke, Iyabode Olabisi Florence, additional, Babatola, Adefunke Olarinre, additional, Adeniyi, Adewuyi Temidayo, additional, Ajite, Adebukola Bidemi, additional, Lawal, Olubunmi Adeola, additional, Taiwo, Adekunle Bamidele, additional, Fatunla, Odunayo Adebukola, additional, Ajibola, Ayotunde Emmanuel, additional, Bolaji, Olufunke Bosede, additional, and Olatunya, Oladele Simeon, additional

Published
2023
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10. A Descriptive Epidemiology of Coagulase-Negative Staphylococci Bacteraemia in a Tertiary Hospital, Southwest Nigeria.

Author

Irek, Emmanuel Oladayo, primary, Fajoyegbe, Emmanuel Sunday, additional, Fatunla, Odunayo Adebukola Temitope, additional, Oyebanji, Adedayo Hakeem, additional, Kiyesi, Adekemi, additional, Adebayo, Adeshola, additional, Anuforo, Anthony Chinemere, additional, Odele, Richmond, additional, Ogundare, Ezra Olatunde, additional, Babalola, Tosin Odunayo, additional, Adebisi, Temidayo Deborah, additional, Ihetu, Josephine Chijioke, additional, Fayomi, Mosunmola Margaret, additional, Akimade, Akinola, additional, and Ogundipe, Kolawole Olubunmi, additional

Published
2023
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11. Breastfeeding: Knowledge, Perception, And Intention to Practice Among Female Students of Tertiary Institutions in Ekiti, Southwest Nigeria.

Author

Ogundare, Ezra, Babatola, Adefunke, Omoyajowo, Adefunke, Ajite, Adebukola, Adeniyi, Adewuyi, Fatunla, Odunayo, Ojo, Temitope, Agbesanwa, Tosin, Olubosede, Omolayo, Taiwo, Adekunle, Oluyi, Adedayo, Ajibola, Ayotunde, Komolafe, Akinwumi, Airemionkhale, Alfred, Oluwayemi, Isaac, and Olatunya, Oladele

Subjects
BREASTFEEDING techniques, INFERENTIAL statistics, RESEARCH evaluation, CROSS-sectional method, WOMEN, TERTIARY care, HEALTH literacy, UNDERGRADUATES, CRONBACH'S alpha, DESCRIPTIVE statistics, CHI-squared test, INTENTION, STUDENT attitudes, STATISTICAL sampling, DATA analysis software, LONGITUDINAL method
Abstract

Introduction: Breastfeeding is a public health practice that is critical for the survival of infants and young children. This study aimed at determining the knowledge, attitude, and future intention to breastfeed among female undergraduates in tertiary institutions in Ekiti State, Southwest Nigeria. Methodology: A prospective cross-sectional study was conducted among 1312 female students of the tertiary institutions in Ekiti State. By convenience sampling, female students were invited to participate in the study after giving verbal consent and those studying medical, nursing, and other courses allied to medicine were excluded. Internal consistency of the data obtained from this research instrument was determined using Cronbach's coefficient Alpha with a reliability value of 0.82. Data analysis was conducted using SPSS version 25. Descriptive as well as inferential statistics were computed. Results were summarized as frequencies and percentages. The differences in knowledge, attitude, and intention to practice breastfeeding as well as other responses among the participants were compared among age groups, faculties and the sources of information using Chi-square test. Result: Although 93% of the respondents agreed that breast milk is important for the development of the infant's brain thereby demonstrating good knowledge; 51.6% of the respondents demonstrated poor perception to breastfeeding believing breastfeeding makes the breast to sag while only 34% of the respondents indicated their intention to breastfeed their future babies. Conclusion: The intention to breastfeed among our study participants was poor. This study revealed the need to increase awareness about breastfeeding and its benefits among this huge population of future mothers. [ABSTRACT FROM AUTHOR]

Published
2023
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13. Blood pressure and electrocardiographic profile of children with sickle cell anaemia in steady-state and vaso-occlusive crisis.

Author

Adeniyi, Adewuyi T., Adegoke, Samuel A., Olatunya, Oladele S., Babatola, Adefunke O., Ajite, Adebukola B., Ogundare, Ezra O., Oluwayemi, Isaac O., Abe-Dada, Adedolapo A., and Okeniyi, John A. O.

Subjects
SICKLE cell anemia, BLOOD pressure, HEALTH facilities, CARDIOVASCULAR diseases, HYPERTENSIVE crisis, PEDIATRIC clinics, HEART block
Abstract

Objective: To compare the cardiovascular features of patients with sickle cell anaemia (SCA) in steady-state with those in vaso-occlusive crisis (VOC) at the Wesley Guild Hospital (WGH). Design: A descriptive cross-sectional, matched, case-control study among children with SCA at the WGH, a tertiary health facility in southwest Nigeria. Setting: The participants were recruited from the children's emergency unit and paediatric haematology clinic of the WGH. Participants: Consisted of 93 children with VOC (cases) and 93 age and sex-matched in steady state (controls), aged 5 - 15 years. Main outcome measures: Cardiovascular parameters, including pulse rate, blood pressure, and electrocardiographic profile, were assessed and compared using the appropriate statistical tests. Results: The mean (SD) age of the cases and controls were 8.8 (3.2) years and 9.0 (3.1) years, respectively (p= 0.106). There was no significant difference in the mean height of the groups. The mean pulse rate, diastolic, systolic, and mean arterial pressures were significantly higher in the cases than in the controls. A significantly higher proportion of the cases than the controls also had a higher frequency of heart blocks, prolonged QTc interval, ST elevation or depression, and T wave abnormality (p = 0.018, 0.039, 0.041, 0.009, respectively). The prevalence of chamber enlargements was not significantly different between the two groups. Conclusion: Cardiovascular dysfunction is worse during VOC when compared with steady state. Physicians should look for these dysfunctions in SCA children with VOC to reduce mortality from the disease. [ABSTRACT FROM AUTHOR]

Published
2023
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14. Incidence of Catastrophic Health Expenditures Amongst Hospitalized Neonates in Ekiti, Southwest Nigeria

Author

Ogundare,Ezra Olatunde, Taiwo,Adekunle, Olatunya,Oladele Simeon, Afolabi,Muhammed Olarewaju, Ogundare,Ezra Olatunde, Taiwo,Adekunle, Olatunya,Oladele Simeon, and Afolabi,Muhammed Olarewaju

Abstract

Ezra O Ogundare,1,2 Adekunle B Taiwo,3 Oladele S Olatunya,1,2 Muhammed O Afolabi4 1Department of Paediatrics, Ekiti State University, Ado-Ekiti, Nigeria; 2Department of Paediatrics and Child Health, Ekiti State University Teaching Hospital, Ado Ekiti, Nigeria; 3Department of Paediatrics, Zankli Medical Services, Abuja, Nigeria; 4Department of Disease Control, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UKCorrespondence: Ezra O Ogundare, Department of Paediatrics, Ekiti State University, Ado-Ekiti, Nigeria, Tel +234-803-501-7416, Email ogundarezra@gmail.comBackground: Neonatal illnesses require huge spending due to prolonged hospital stay. The management of these illnesses is usually financed by individual families which in most instances are living below the poverty line. This healthcare financing method can readily push families into catastrophic spending on health.Aim: To ascertain the average cost of managing common neonatal illnesses and the financial burden, it constitutes to families in Ekiti State, southwest Nigeria.Methods: We conducted a cross-sectional study on the out-of-pocket spending involved in managing neonates admitted into and discharged from the SCBU of the Ekiti State University Teaching Hospital, Ado-Ekiti, southwest Nigeria. Data collected included the monthly family income, the money spent on drugs, laboratory investigations and the hospital bill using a purposely designed structured questionnaire. Healthcare spending greater than 10% of the overall family income was described as catastrophic health spending (CHS).Results: The medical bills for most (95%) of the 119 study participants were paid through the out-of-pocket means and 81.5% of the families spent more than 10% of their monthly earnings (CHS) to settle medical bills. Close to 50% of the families belonged to the lower social economic class. The median (IQR) duration of hospital stay was 2.75 days (3.0– 8.0). The median (IQR)

Published
2022

17. A ten-year review of neonatal tetanus cases managed at a tertiary health facility in a resource poor setting: The trend, management challenges and outcome

Author

Ogundare, Ezra Olatunde, primary, Ajite, Adebukola Bidemi, additional, Adeniyi, Adewuyi Temidayo, additional, Babatola, Adefunke Olarinre, additional, Taiwo, Adekunle Bamidele, additional, Fatunla, Odunayo Adebukola, additional, Airemionkhale, Alfred, additional, Odeyemi, Oluwapelumi Adeyosola, additional, Olatunya, Oladele Simeon, additional, and Oyelami, Oyeku Akibu, additional

Published
2021
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18. Paediatric brought-in-dead at a tertiary health facility in South western Nigeria: Patterns and drivers

Author

Olatunya, Oladele S., primary, Babatola, Adefunke O., additional, Adeniyi, Adewuyi T., additional, Ajite, Adebukola B., additional, Oluwayemi, Isaac O., additional, Ogundare, Ezra O., additional, Fatunla, Odunayo A., additional, Komolafe, Akinwumi K., additional, Taiwo, Adekunle B., additional, Airemionkhale, Alfred, additional, Ajibola, Ayotunde E., additional, Sola-Oniyide, Boluwatife A., additional, Adebisi, Adewale O., additional, Ilori, Benjamin F., additional, and Oyelami, Oyeku A., additional

Published
2021
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20. Pediatric Discharges Against Medical Advice: A Review of Cases in Ado-Ekiti, Nigeria

Author

Babatola, Adefunke Olarinre, primary, Olatunya, Oladele Simeon, additional, Ogundare, Ezra Olatunde, additional, Ajibola, Ayotunde Emmanuel, additional, Ojo, Temitope Olumuyiwa, additional, Oluwayemi, Isaac Oludare, additional, Ajite, Adebukola Bidemi, additional, Adeniyi, Adewuyi Temidayo, additional, Komolafe, Akinwumi Kolawole, additional, Fadare, Joseph Olusesan, additional, and Oyelami, Oyeku Akibu, additional

Published
2021
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21. Breastfeeding: Knowledge, Perception, And Intention to Practice Among Female Students of Tertiary Institutions in Ekiti, Southwest Nigeria

Author

Ogundare, Ezra, primary, Babatola, Adefunke, additional, Omoyajowo, Adefunke, additional, Ajite, Adebukola, additional, Adeniyi, Adewuyi, additional, Fatunla, Odunayo, additional, Ojo, Temitope, additional, Agbesanwa, Tosin, additional, Olubosede, Omolayo, additional, Taiwo, Adekunle, additional, Oluyi, Adedayo, additional, Ajibola, Ayotunde, additional, Komolafe, Akinwumi, additional, Airemionkhale, Alfred, additional, Oluwayemi, Isaac, additional, and Olatunya, Oladele, additional

Published
2021
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22. sj-pdf-1-qch-10.1177_0272684X211034349 - Supplemental material for BREASTFEEDING: KNOWLEDGE, PERCEPTION, AND INTENTION TO PRACTICE AMONG FEMALE STUDENTS OF TERTIARY INSTITUTIONS IN EKITI, SOUTHWEST NIIGERIA

Author

Ogundare, Ezra, Babatola, Adefunke, Omoyajowo, Adefunke, Ajite, Adebukola, Adeniyi, Adewuyi, Fatunla, Odunayo, Ojo, Tope, Agbesanwa, Tosin, Olubosede, Omolayo, Taiwo, Adekunle, Oluyi, Adedayo, Ajibola, Ayotunde, Komolafe, Akinwumi, Airemionkhale, Alfred, Oluwayemi, Isaac, and Olatunya, Oladele

Subjects
111799 Public Health and Health Services not elsewhere classified, FOS: Health sciences
Abstract

Supplemental material, sj-pdf-1-qch-10.1177_0272684X211034349 for BREASTFEEDING: KNOWLEDGE, PERCEPTION, AND INTENTION TO PRACTICE AMONG FEMALE STUDENTS OF TERTIARY INSTITUTIONS IN EKITI, SOUTHWEST NIIGERIA. by Ezra Ogundare, Adefunke Babatola, Adefunke Omoyajowo, Adebukola Ajite, Adewuyi Adeniyi, Odunayo Fatunla, Tope Ojo, Tosin Agbesanwa, Omolayo Olubosede, Adekunle Taiwo, Adedayo Oluyi, Ayotunde Ajibola, Akinwumi Komolafe, Alfred Airemionkhale, Isaac Oluwayemi and Oladele Olatunya in International Quarterly of Community Health Education

Published
2021
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23. Neonatal Jaundice: Perception of Pregnant Women Attending Antenatal Clinic at a Tertiary Hospital in Southwest, Nigeria

Author

Fatunla Odunayo Adebukola, Omoyajowo Adefunke Christianah, Ajite Adebukola Bidemi, Olatunya Oladele Simeon, Ogundare Ezra Olatunde, Oluwayemi Isaac Oludare, Taiwo Adekunle Bamidele, Babatola Adefunke Olarinre, Adeniyi Adewuyi Temidayo, and Agaja Oyinkansola Tolulope

Subjects
medicine.medical_specialty, media_common.quotation_subject, Good attitude, Reproductive age, Early death, perception, Pediatrics, Danger sign, Awareness campaign, 03 medical and health sciences, 0302 clinical medicine, 030225 pediatrics, Perception, Medicine, 030212 general & internal medicine, media_common, Antenatal clinic, business.industry, Pregnant women, lcsh:RJ1-570, Maternal, Newborn, and Child Morbidity and Mortality, lcsh:Pediatrics, Jaundice, Mental handicap, Family medicine, Pediatrics, Perinatology and Child Health, Original Article, Neonatal jaundice, medicine.symptom, business
Abstract

Background: Severe neonatal jaundice (NNJ) remains a leading cause of preventable brain damage, mental handicap, physical disabilities, and early death among infants. Methods: Using a descriptive cross-sectional study design, information was gathered using a structured, pretested questionnaire from 518 pregnant women who attended the antenatal clinic at a tertiary Hospital in Southwest Nigeria. Results: Most (77%) of the respondents have heard about NNJ prior the survey. Most respondents (69.5%) demonstrated poor knowledge of the causes of NNJ. The majority, 98.4% had good attitude toward treatment of NNJ. Most respondents (72.1%) demonstrated poor knowledge of the correct treatment of NNJ. A quarter of the respondents knew no danger sign of NNJ. Conclusion: There is serious knowledge gap among the respondents about the causes, treatment, dangers signs and complications of NNJ. There is need for increased awareness campaign using every available means of reaching women of reproductive age group to reduce the consequences of this common neonatal problem.

Published
2020

24. A Ten-Year Review of the Pattern and Outcome of Childhood Diabetes in Two State Teaching Hospitals in South-West Nigeria

Author

Oluwayemi,Isaac Oludare, Oyedeji,Olusola Adetunji, Adeniji,Emmanuel Oluwatosin, Ajite,Adebukola Bidemi, Babatola,Adefunke Olarinre, Adeniyi,Adewuyi Temidayo, Ogundare,Ezra Olatunde, Olatunya,Oladele Simeon, Ayeni,Temitope Opeyemi, and Ajibola,Ayotunde Emmanuel

Subjects
Targets and Therapy [Diabetes, Metabolic Syndrome and Obesity]
Abstract

Isaac Oludare Oluwayemi,1 Olusola Adetunji Oyedeji,2 Emmanuel Oluwatosin Adeniji,2 Adebukola Bidemi Ajite,1 Adefunke Olarinre Babatola,1 Adewuyi Temidayo Adeniyi,1,2 Ezra Olatunde Ogundare,1 Oladele Simeon Olatunya,1 Temitope Opeyemi Ayeni,3 Ayotunde Emmanuel Ajibola4 1Department of Paediatrics, Faculty of Clinical Sciences, College of Medicine, Ekiti State University, Ado-Ekiti, Ekiti State, Nigeria; 2Department of Paediatrics, Faculty of Clinical Sciences, College of Health Science, LAUTECH, Osogbo, Osun State, Nigeria; 3Department of Paediatrics, LAUTECH Teaching Hospital, Osogbo, Osun State, Nigeria; 4Department of Paediatrics, Ekiti State University Teaching Hospital, Ado-Ekiti, Ekiti State, NigeriaCorrespondence: Isaac Oludare OluwayemiDepartment of Paediatrics, Faculty of Clinical Sciences, College of Medicine, Ekiti State University, Ado-Ekiti, Ekiti State, NigeriaTel +2348034052536Email isaac.oluwayemi@eksu.edu.ngBackground: Childhood diabetes mellitus is a poorly researched topic in Nigeria. Its contribution to morbidity and mortality is vague. This study intends to provide additional information to the background data in Nigeria and hopefully proffers strategies to improving the outcome of this disease.Methods: This is a retrospective descriptive study of all children managed for childhood diabetes mellitus at the Ekiti State University Teaching Hospital (EKSUTH) and LAUTECH Teaching Hospital (LTH), South West Nigeria, over a 10 year period. Relevant information was obtained from the case notes of all affected children. Data obtained were analysed with SPSS version 20 software.Results: A total of 20 children were treated for diabetes mellitus (DM); there were 7 (35.0%) boys and 13 (65.0%) girls giving a M:F ratio of 1.0:1.9. Age range at presentation was 5 to 16 years and the mean age at presentation was 12.7 ± 2.89 years. Diabetic ketoacidosis (DKA) was the most common form of presentation in 13 (65.0%). Most [18 (90.0%)] of the patients had type 1 DM. Type 2 DM and glucocorticoid-induced diabetes mellitus were recorded in a case each, Eighteen (90%)patients had not been previously diagnosed by any form of screening prior to their presentation and admission in the hospital. Seven (35.0%) of the patient’s care were affected by parental financial constraints. Five mortalities were recorded and one left against medical advice while the majority [14 (70.4%)] were discharged well and alive. The association between the greater numbers of deaths recorded in children with financial constraints was statistically significant (p < 0.05).Conclusion: Type 1 DM remains the most predominant form of diabetes in children and most of the patients presented in DKA. The proportion of deaths in this study is unacceptably high. There is a need to proffer strategies for earlier detection and management of children with diabetes mellitus prior to the onset or development of DKA and there is a need to assist with the funding of the care of children with diabetes mellitus.Keywords: pattern, outcome, childhood diabetes, Nigeria

Published
2020

25. Teething Beliefs, Misconceptions, and Practices Among Mothers Attending a Tertiary Hospital in Nigeria: Implications for Child Health and Clinical Practice

Author

Olatunya, Oladele Simeon, primary, Adeniyi, Adewuyi Temidayo, primary, Babatola, Adefunke Olarinre, primary, Fatunla, Odunayo Tolulope, primary, Olajuyin, Oyebanji Anthony, primary, Ogundare, Ezra Olatunde, primary, Komolafe, Akinwumi Kolawole, primary, Fadare, Joseph Olusesan, primary, and Oyelami, Oyeku Akibu, primary

Published
2020
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26. Perceptions and Practice of Early Diagnosis of Sickle Cell Disease by Parents and Physicians in a Southwestern State of Nigeria

Author

Olatunya, Oladele Simeon, primary, Babatola, Adefunke Olarinre, additional, Ogundare, Ezra Olatunde, additional, Olofinbiyi, Babatunde Ajayi, additional, Lawal, Olubunmi Adeola, additional, Awoleke, Jacob Olumuyiwa, additional, Aduloju, Olusola Peter, additional, Daramola, Alaba Olanrewaju, additional, Emmanuel, Eyitayo Ebenezer, additional, Olajuyin, Oyebanji Anthony, additional, Komolafe, Akinwumi Kolawole, additional, and Olaleye, Abiola Olukayode, additional

Published
2020
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27. Neonatal Jaundice: Perception of Pregnant Women Attending Antenatal Clinic at a Tertiary Hospital in Southwest, Nigeria

Author

Olatunde, Ogundare Ezra, primary, Christianah, Omoyajowo Adefunke, additional, Olarinre, Babatola Adefunke, additional, Bidemi, Ajite Adebukola, additional, Temidayo, Adeniyi Adewuyi, additional, Adebukola, Fatunla Odunayo, additional, Tolulope, Agaja Oyinkansola, additional, Bamidele, Taiwo Adekunle, additional, Oludare, Oluwayemi Isaac, additional, and Simeon, Olatunya Oladele, additional

Published
2020
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30. Within-Host Diversity and Vertical Transmission of Group B Streptococcus Among Mother-infant Dyads in The Gambia

Author

Foster-Nyarko, Ebenezer, primary, Senghore, Madikay, additional, Kwambana-Adams, Brenda A., additional, Alikhan, Nabil-Fareed, additional, Ravi, Anuradha, additional, Jafali, James, additional, Jawneh, Kaddijatou, additional, Jah, Amara, additional, Jarju, Maimuna, additional, Ceesay, Fatima, additional, Bojang, Sainabou, additional, Worwui, Archibald, additional, Odutola, Aderonke, additional, Ogundare, Ezra, additional, Pallen, Mark J., additional, Ota, Martin, additional, and Antonio, Martin, additional

Published
2019
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31. Immunogenicity of pneumococcal conjugate vaccine formulations containing pneumococcal proteins, and immunogenicity and reactogenicity of co-administered routine vaccines – A phase II, randomised, observer-blind study in Gambian infants

Author

Odutola, Aderonke, primary, Ota, Martin O.C., additional, Antonio, Martin, additional, Ogundare, Ezra O., additional, Saidu, Yauba, additional, Owiafe, Patrick K., additional, Worwui, Archibald, additional, Idoko, Olubukola T., additional, Owolabi, Olumuyiwa, additional, Kampmann, Beate, additional, Greenwood, Brian M., additional, Alderson, Mark, additional, Traskine, Magali, additional, Swinnen, Kristien, additional, Verlant, Vincent, additional, Dobbelaere, Kurt, additional, and Borys, Dorota, additional

Published
2019
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35. Prescription audit in a paediatric sickle cell clinic in South-West Nigeria: A cross-sectional retrospective study

Author

Olatunya Oladele Simeon, Fadare Joseph Olusesan, Oluwayemi Isaac Oludare, Agaja Oyinkansola Tolulope, and Ogundare Ezra Olatunde

Subjects
Male, Pediatrics, medicine.medical_specialty, Adolescent, Anemia, Cross-sectional study, medicine.drug_class, Antibiotics, Nigeria, Anemia, Sickle Cell, Ambulatory Care Facilities, Drug Prescriptions, medicine, Humans, Outpatient clinic, Medical prescription, Child, Hospitals, Teaching, Original Research, Retrospective Studies, Analgesics, business.industry, Standard treatment, Medical record, Infant, Retrospective cohort study, General Medicine, medicine.disease, Anti-Bacterial Agents, Cross-Sectional Studies, Child, Preschool, Female, business
Abstract

Background: Sickle cell disease (SCD) is a genetic haematological disorder that affects millions of people around the world especially people of African heritage. The treatment of the symptoms of SCD includes the use of analgesics, antibiotics, and anti-malarial drugs. Studying the pattern of drug prescription is a veritable tool for establishing the current practice and how it conforms to existing guidelines. Objectives: The main objective of this study was to assess the pattern of drug prescription in children with sickle cell disease (SCD) attending the paediatric outpatients’ clinic of a tertiary care centre in Ado-Ekiti, South-West Nigeria. Methods: This was a cross-sectional retrospective study carried out using the medical records of all patients with SCD who attended the paediatric outpatient clinic of the teaching hospital between January 1 and December 31, 2014. The information retrieved from the case notes included the bio-demographic data, associated co-morbid conditions and the list of prescribed drugs. Results: A total of 202 SCD patients aged below 18 years were seen in the clinic during the study period with males accounting for 61.9% of them. The mean age of all patients was 6.9 ±3.8 yrs. A total of 1015 medications were prescribed during the study period giving a mean of 5.02 ± 1.9. Vitamins/micronutrients, anti-malarial drugs, antibiotics and analgesics accounted for 41.4%, 29.0%, 15.7% and 13.9% of all prescribed drugs respectively. Antibiotics from the penicillin group were the most commonly prescribed followed by macrolides and cephalosporins while Ibuprofen (60.3%) and Acetaminophen (32.6%) were the commonly prescribed analgesics. Conclusion: High rate of antibiotic prescription, low use of opioid analgesics and non- prescription of prophylactic penicillin/ pneumococcal vaccination were the main findings in this study. There is need for the introduction of standard treatment protocols for this group of patients.

Published
2018
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36. Congenital Diaphragmatic Hernia

Author

Ogundare, Ezra Olatunde, primary, Olatunya, Oladele Simeon, primary, Ajite, Adebukola Abidemi, primary, Oluwayemi, Isaac Oludare, primary, Fatunla, Odunayo Adebukola, primary, Omoniyi, Evelyn Omosede, primary, Odiase, Oboite, primary, and Ige, Joshua Taye, primary

Published
2017
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37. Efficacy of a novel, protein-based pneumococcal vaccine against nasopharyngeal carriage of Streptococcus pneumoniae in infants: A phase 2, randomized, controlled, observer-blind study

Author

Odutola, Aderonke, primary, Ota, Martin O.C., additional, Antonio, Martin, additional, Ogundare, Ezra O., additional, Saidu, Yauba, additional, Foster-Nyarko, Ebenezer, additional, Owiafe, Patrick K., additional, Ceesay, Fatima, additional, Worwui, Archibald, additional, Idoko, Olubukola T., additional, Owolabi, Olumuyiwa, additional, Bojang, Abdoulie, additional, Jarju, Sheikh, additional, Drammeh, Isatou, additional, Kampmann, Beate, additional, Greenwood, Brian M., additional, Alderson, Mark, additional, Traskine, Magali, additional, Devos, Nathalie, additional, Schoonbroodt, Sonia, additional, Swinnen, Kristien, additional, Verlant, Vincent, additional, Dobbelaere, Kurt, additional, and Borys, Dorota, additional

Published
2017
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39. Knowledge, attitudes and screening practices regarding prostatic diseases among men older than 40 years: a population-based study in Southwest Nigeria

Author

Ojewola, Rufus Wale, primary, Oridota, Ezekiel Sofela, additional, Balogun, Olanrewaju Samuel, additional, Ogundare, Ezra Olatunde, additional, Alabi, Taiwo Opeyemi, additional, Banjo, Oluseyi Omotola, additional, Laoye, Adeyinka, additional, Adetunmbi, Babatunde, additional, Adebayo, Bamidele Oludele, additional, and Oluyombo, Rotimi, additional

Published
2017
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41. Acute hypervitaminosis A misdiagnosed as malaria in a 7-year-old Nigerian boy.

Author

Babatola, Adefunke Olarinre, Olatunya, Oladele Simeon, Ogundare, Ezra Olatunde, Ajite, Adebukola Bidemi, Oluwayemi, Isaac Oludare, Thomas, Awolowo Anthony, Taiwo, Adekunle Bamidele, Fatunla, Odunayo Adebukola, Komolafe, Akinwumi Kolawole, and Alfred, Airemionkhale

Subjects
MALARIA, DIETARY supplements
Abstract

Vitamin A supplementation program where single high-dose vitamin A supplements are provided to the qualified (infants and children) at regular intervals is operational in Nigeria as a public health initiative to control vitamin A deficiency which is prevalent in our country in accordance with the WHO recommendations. Reports of symptomatic acute hypervitaminosis A are scarce. We report a case of acute hypervitaminosis A resulting from accidental ingestion of vitamin A supplement capsules. This is to reiterate the need for caregivers to keep drugs out of the reach of children. Clinicians should also have a high index of suspicion. [ABSTRACT FROM AUTHOR]

Published
2019
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42. Evaluation of a Portable Haemoglobin Metre Performance in Children with Sickle Cell Disease and Implications for Healthcare in Resource-poor Settings

Author

Olatunya, Oladele Simeon, primary, Olu-Taiwo, Adebola, additional, Ogundare, Ezra Olatunde, additional, Oluwayemi, Isaac Oludare, additional, Olaleye, Abiola Olukayode, additional, Fadare, Joseph Olusesan, additional, Adekoya-Benson, Tolulope, additional, Fatunla, Odunayo, additional, Agaja, Oyinkansola Tolulope, additional, Omoniyi, Evenly, additional, and Oluwadiya, Kehinde Sunday, additional

Published
2016
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45. The financial burden of sickle cell disease on households in Ekiti, Southwest Nigeria

Author

Olatunya,Oladele Simeon, Ogundare,Ezra Olatunde, Fadare,Joseph Olusesan, Oluwayemi,Isaac Oludare, Agaja,Oyinkansola Tolulope, Adeyefa,Babajide Samson, Aderiye,Odunayo, Olatunya,Oladele Simeon, Ogundare,Ezra Olatunde, Fadare,Joseph Olusesan, Oluwayemi,Isaac Oludare, Agaja,Oyinkansola Tolulope, Adeyefa,Babajide Samson, and Aderiye,Odunayo

Abstract

Oladele Simeon Olatunya,1,3 Ezra Olatunde Ogundare,1,3 Joseph Olusesan Fadare,2 Isaac Oludare Oluwayemi,1,3 Oyinkansola Tolulope Agaja,3 Babajide Samson Adeyefa,3 Odunayo Aderiye3 1Department of Paediatrics, Ekiti State University, Ado Ekiti, Nigeria; 2Department of Clinical Pharmacology, Ekiti State University, Ado Ekiti, Nigeria; 3Department of Paediatrics, Ekiti State University Teaching Hospital, Ado Ekiti, Nigeria Background: Studies on economic impact of sickle cell disease (SCD) are scanty despite its being common among children in developing countries who are mostly Africans.Objective: To determine the financial burden of SCD on households in Ado Ekiti, Southwest Nigeria.Methods: A longitudinal and descriptive study of household expenditures on care of 111 children with SCD managed at the pediatric hematology unit of the Ekiti State University Teaching Hospital was conducted between January and December 2014.Results: There were 64 male and 47 female children involved, aged between 15 and 180 months. They were from 111 households, out of which only eight (7.2%) were enrolled under the National Health Insurance Scheme. The number of admissions and outpatients' consultations ranged from 1 to 5 and 1 to 10 per child, respectively. Malaria, vaso-occlusive crisis, and severe anemia were the leading comorbidities. The monthly household income ranged between ₦12,500 and ₦330,000 (US$76 and US$2,000) with a median of ₦55,000 (US$333), and health expenditure ranged between ₦2,500 and ₦215,000 (US$15 and US$1,303) with a mean of ₦39,554±35,479 (US$240±215). Parents of 63 children lost between 1 and 48 working days due to their children's ill health. Parents of 23 children took loans ranging between ₦6,500 and ₦150,000 (US$39 and US$909) to offset hospital bills. The percentage of family income spent as health expenditure on each child ranged from 0.38 to 34.4. Catastrophic health expenditure (when the health expendi

Published
2015

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