1,735 results on '"Octet"'
Search Results
2. Perfecting the Puzzle of Pathophysiology: Exploring Combination Therapy in the Treatment of Type 2 Diabetes
- Author
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Ridhi Gudoor, Austen Suits, and Jay H. Shubrook
- Subjects
diabetes ,combination therapy ,octet ,Diseases of the blood and blood-forming organs ,RC633-647.5 - Abstract
Type 2 diabetes mellitus (T2DM) is a debilitating, lifelong condition with a rising incidence. A wide variety of antihyperglycemic agents are available on the market to treat diabetes. However, the number of patients living with diabetes under suboptimal control remains relatively high. This calls into question whether the application of the current treatment standards is effective and durable to truly manage the disease well. This paper aims to highlight the various classes of antihyperglycemic agents from a pathophysiologic perspective and explore the best possible combination that can have a durable effect on diabetes management. To determine this, an eight-piece pathophysiologic puzzle was created, each piece representing an organ system affected by the disease—liver, pancreas (alpha and beta cells), muscle, adipose tissue, gut, brain, and kidneys. Choosing a combination therapy that is both durable and can effectively address all eight pieces of the puzzle can theoretically create sustainable ameliorating effects. This combination can potentially lead to reduced microvascular and macrovascular complications, as well as work towards creating an ideal long-term, affordable diabetes care plan.
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- 2023
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3. Conjugate heat transfer in lattice frame materials based on novel unit cell topologies.
- Author
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Kaur, Inderjot and Singh, Prashant
- Subjects
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HEAT transfer , *UNIT cell , *HEAT transfer coefficient , *THERMAL resistance , *PRESSURE drop (Fluid dynamics) - Abstract
This article presents conjugate heat transfer characteristics of strut-based sandwich-type configurations obtained through reticulation of unit cell topologies of Tetrakaidecahedron, Octet and Rhombic dodecahedron shapes (porosity ∼0.90) with water as working fluid. Tetrakaidecahedron lattice exhibited the highest overall heat transfer coefficient, followed by Octet and Rhombic dodecahedron, respectively. Pressure drop was the highest for Octet, followed by Rhombic dodecahedron, and Tetrakaidecahedron, respectively. Thickness of struts in contact with endwall played a dominant role in conjugate thermal exchange of sandwich configurations. For the investigated conditions, Tetrakaidecahedron-shape based lattice provided the least thermal resistance value at any given pumping power condition. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
4. Viscoelastic Damping and Wave Cutoff of Titanium Alloy and Lattices.
- Author
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Goyal, Karan, Rueger, Zach, Davis, Evan, and Lakes, Roderic S.
- Subjects
RESONANT ultrasound spectroscopy ,FREE vibration ,METAMATERIALS ,THREE-dimensional printing - Abstract
The 3D‐printed titanium alloy Ti5553 solid and octet truss lattice specimens are studied via resonant ultrasound spectroscopy, free decay of vibration and quasi‐static methods to determine viscoelastic damping. Damping in solid alloy and a lattice is between 10−4 and10−3. Much of the damping at high sonic frequency is attributed to stress‐induced heat flow between heterogeneities due to 3D printing. Pulsed wave ultrasound experiments disclose reverberation in the cell structure of the lattice. Continuous wave ultrasound experiments show that the transmissibility in the lattice rolls off beginning at about 50 kHz and becomes negligible above 110 kHz. By contrast, the polymer polymethyl methacrylate (PMMA), though it is viscoelastic, readily transmits waves up to 1 MHz. The cutoff frequency in the lattice is associated with the structure size, not intrinsic damping in the alloy. The octet truss lattice, in addition to providing good mechanical performance, is also an ultrasonic metamaterial. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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5. Biolayer Interferometry Analysis for a Higher Throughput Quantification of In-Process Samples of a Rotavirus Vaccine.
- Author
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Carvalho, Sofia B., Dias, Mafalda M., Matheise, Jean-Philippe, Knott, Isabelle, Gomes-Alves, Patrícia, and Alves, Paula M.
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ROTAVIRUS vaccines ,ROTAVIRUS diseases ,INTERFEROMETRY ,VACCINE manufacturing ,VACCINATION ,GLYCOCALYX - Abstract
Rotavirus A infection is a global leading cause of severe acute gastroenteritis associated with life-threatening diarrheal episodes in infants and young children. The disease burden is being reduced, namely due to a wider access to rotavirus vaccines. However, there is a demand to expand rotavirus vaccination programs, and to achieve this, it is critical to improve high-throughput in-process product quality control and vaccine manufacturing monitoring. Here, we present the development of an analytical method for the quantification of rotavirus particles contained in a licensed vaccine. The binding of rotavirus proteins to distinct glycoconjugate receptors and monoclonal antibodies was evaluated using biolayer interferometry analysis, applied on an Octet platform. The antibody strategy presented the best results with a linear response range within 2.5 × 10
7 –1.0 × 108 particles·mL−1 and limits of detection and quantification of 2.5 × 106 and 7.5 × 106 particles·mL−1 , respectively. Method suitability for the quantification of in-process samples was shown using samples from different manufacturing stages and their titers were comparable with the approved CCID(50) method. This cell-free method enables a fast and high-throughput analysis, compatible with time constraints during bioprocess development and it is suitable to be adapted to other viral particle-based drug products. [ABSTRACT FROM AUTHOR]- Published
- 2022
- Full Text
- View/download PDF
6. Direct Pore-Scale Simulations of Fully Periodic Unit Cells of Different Regular Lattices.
- Author
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Kaur, Inderjot and Singh, Prashant
- Subjects
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HEAT transfer coefficient , *FOAM , *METAL foams , *UNIT cell , *REYNOLDS number , *HEAT exchangers , *PRESSURE drop (Fluid dynamics) , *NUSSELT number - Abstract
Open-cell metal foams are known for their superior heat dissipation capabilities. The morphological, pressure drop, and heat transfer characteristics of stochastic metal foams manufactured through traditional "foaming" processes are well established in the literature. However, employment of stochastic metal foams in next-generation heat exchangers is challenged by the irregularity in the pore- and fiber-geometries, limited control on the pore-volume, and an inherent necessity of a bonding agent between foam and the heat source. On the other hand, additive manufacturing (AM) is capable of printing complex user-defined unit cell topologies with customized fiber shapes directly on the substrates subjected to heat load. Moreover, the user-defined regular lattices are capable of exhibiting better thermal and mechanical properties than stochastic metal foams. In this paper, we present a numerical investigation on fully periodic unit-cells of three different topologies, that is, tetrakaidecahedron (TKD), rhombic-dodecahedron (DDC), and Octet with air as the working fluid. Pressure gradient, interfacial heat transfer coefficient, friction factor, and Nusselt number are reported for each topology. Rhombic-dodecahedron yielded the highest averaged interfacial heat transfer coefficient whereas Octet incurred the highest flow losses. Pore diameter, defined as the maximum diameter of a sphere passing through the polygonal openings of the structures, when used as the characteristic length scale for the presentation of Nusselt number and Reynolds number, resulted in a single trendline for all the three topologies. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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7. Heavy color-octet particles at the LHC
- Author
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Lee, Keith [Perimeter Inst. for Theoretical Physics, Waterloo, ON (Canada); Univ. of Waterloo, ON (Canada). Dept. of Physics & Astronomy]
- Published
- 2015
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8. High-Throughput Process Development for Biopharmaceuticals
- Author
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Shukla, Abhinav A., Rameez, Shahid, Wolfe, Leslie S., Oien, Nathan, Belkin, Shimshon, Editorial Board Member, Bley, Thomas, Editorial Board Member, Bohlmann, Jörg, Editorial Board Member, Gu, Man Bock, Editorial Board Member, Hu, Wei Shou, Editorial Board Member, Mattiasson, Bo, Editorial Board Member, Seitz, Harald, Editorial Board Member, Zeng, An-Ping, Editorial Board Member, Zhong, Jian-Jiang, Editorial Board Member, Kiss, Bob, editor, Gottschalk, Uwe, editor, and Pohlscheidt, Michael, editor
- Published
- 2018
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9. Biolayer Interferometry Analysis for a Higher Throughput Quantification of In-Process Samples of a Rotavirus Vaccine
- Author
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Sofia B. Carvalho, Mafalda M. Dias, Jean-Philippe Matheise, Isabelle Knott, Patrícia Gomes-Alves, and Paula M. Alves
- Subjects
rotavirus vaccine ,Octet ,in-process samples ,quantification ,bioanalytics ,Medicine - Abstract
Rotavirus A infection is a global leading cause of severe acute gastroenteritis associated with life-threatening diarrheal episodes in infants and young children. The disease burden is being reduced, namely due to a wider access to rotavirus vaccines. However, there is a demand to expand rotavirus vaccination programs, and to achieve this, it is critical to improve high-throughput in-process product quality control and vaccine manufacturing monitoring. Here, we present the development of an analytical method for the quantification of rotavirus particles contained in a licensed vaccine. The binding of rotavirus proteins to distinct glycoconjugate receptors and monoclonal antibodies was evaluated using biolayer interferometry analysis, applied on an Octet platform. The antibody strategy presented the best results with a linear response range within 2.5 × 107–1.0 × 108 particles·mL−1 and limits of detection and quantification of 2.5 × 106 and 7.5 × 106 particles·mL−1, respectively. Method suitability for the quantification of in-process samples was shown using samples from different manufacturing stages and their titers were comparable with the approved CCID(50) method. This cell-free method enables a fast and high-throughput analysis, compatible with time constraints during bioprocess development and it is suitable to be adapted to other viral particle-based drug products.
- Published
- 2022
- Full Text
- View/download PDF
10. Architected Conducting Polymers
- Author
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Frye, Jacob
- Subjects
Materials Science ,3D printing ,conducting polymers ,lattice ,materials science ,metamaterials ,octet - Abstract
Conducting polymers offer the ability to create electronic devices that are lightweight with relatively simple processing compared to their inorganic counterparts. They have recently gained attention in the wearable electronics field due their ability to exhibit flexibility and low stiffness while conducting electricity. However, conducting polymers are not intrinsically flexible and must be modified, usually at the expense of electrical performance, or through the use of expensive and toxic additives. Here, we explore the use of architected materials to tune a conductive polymer's mechanical properties without chemical modification. To do so, a reliable and high-throughput 3D printing system for a conducting polymer-based hydrogel was established. The system utilizes a stereolithography apparatus (SLA) to 3D print a hydrogel of almost any 3D shape. The hydrogel acts as a dopant and structural component for a subsequently grown conducting polymer. This means a conducting polymer, which is usually limited to being a thin film or a stochastic foam, can be made into specific and complex geometries, enabling the tailoring of its mechanical properties through architecture, without compositing or chemical modification. When architected into a lattice, the conducting polymers can withstand compressive strain up to 80% without failure, whereas their bulk counterpart reaches just 25% strain before undergoing brittle fracture. The architected conducting polymers also exhibit a strain rate invariant stress-strain curve, suggesting that a potential strain rate invariant electrical resistance behavior may exist, but further investigation is required.
- Published
- 2020
11. Coulomb force on a line charge in an anisotropic piezoelectric bimaterial
- Author
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Xu Wang and Peter Schiavone
- Subjects
Physics ,Surface (mathematics) ,010304 chemical physics ,Condensed matter physics ,Octet ,General Physics and Astronomy ,Charge (physics) ,010402 general chemistry ,01 natural sciences ,Piezoelectricity ,0104 chemical sciences ,Coulomb's law ,symbols.namesake ,Mechanics of Materials ,Orientation (geometry) ,0103 physical sciences ,Line (geometry) ,symbols ,General Materials Science ,Anisotropy - Abstract
We employ the Stroh octet formalism to develop a real-form expression of the Coulomb force acting on a line charge in an anisotropic piezoelectric bimaterial. The Coulomb force is derived using two different approaches and is expressed in terms of the generalized Barnett–Lothe tensors for the two piezoelectric half-spaces. Interestingly, we find that the Coulomb force is independent of the orientation of the bimaterial interface provided that the interface is parallel to the $$x_{3}$$ -axis and the distance between the charge and the interface remains unchanged. The Coulomb force on a line charge in a piezoelectric half-space with a rigid conducting surface or a traction-free insulating surface is deduced from the Coulomb force for two jointed piezoelectric half-spaces. In the case of a rigid conducting surface, we find that the Coulomb force always tends to attract the line charge to the surface. This is in contract to the case of a traction-free insulating surface for which we find that the Coulomb force can be either repulsive or attractive due to the piezoelectric effect.
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- 2021
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12. Another Way of Handling Strangers
- Author
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Al-Haj Baddar, Sherenaz W., Batcher, Kenneth E., Al-Haj Baddar, Sherenaz W., and Batcher, Kenneth E.
- Published
- 2011
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13. Sorting Networks For Large N
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Al-Haj Baddar, Sherenaz W., Batcher, Kenneth E., Al-Haj Baddar, Sherenaz W., and Batcher, Kenneth E.
- Published
- 2011
- Full Text
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14. Primerjava analiznih metod za določanje koncentracij monoklonskih protiteles in fuzijskih proteinov
- Author
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Modrijan, Tina and Narat, Mojca
- Subjects
Octet ,Cedex ,monoklonsko protitelo ,monoclonal antibody ,CHO ,fuzijski protein ,fusion protein ,HPLC ,ValitaTiter - Abstract
Koncentracijo monoklonskih protiteles (mAb) in fuzijskih proteinov lahko določamo z različnimi bioanalitskimi metodami in napravami. Med slednjimi afinitetna tekočinska kromatografija visoke ločljivosti (HPLC) velja za zlati standard. Ker je pridobivanje rezultatov s HPLC zelo zamudno, so se na trgu začele pojavljati številne alternativne visokozmogljive bioanalitske metode in naprave. Mednje lahko uvrstimo naprave družine Cedex, kjer določanje koncentracije produkta poteka z metodo imunske turbidimetrije, in Octet, ki temelji na interferometriji bioloških plasti, ter metodo ValitaTiter, s katero koncentracijo mAb in fuzijskih proteinov določamo na podlagi sprememb v polarizaciji svetlobe. Namen magistrske naloge je bil raziskati odstopanja med meritvami na HPLC in preostalimi visokozmogljivimi metodami oziroma napravami. Poleg tega smo želeli preveriti, ali proces ločevanja produktov od večjih nečistoč in zamrzovanje vzorcev vplivata na meritve naprav Cedex Bio HT. Za proučevanje potencialnega vpliva strukture molekul rekombinantnih proteinov na razlike med meritvami naprav, smo v eksperiment vključili štiri celične linije CHO, ki proizvajajo IgG1, IgG2, IgG4 in Fc-fuzijski protein. Tekom 14-dnevne produkcijske faze je potekalo dnevno vzorčenje bioprocesnih brozg. Ugotovili smo, da zamrzovanje vzorcev in postopek primarnega ločevanja nimata vplivata na meritve koncentracije produktov in da je odstopanje meritev na preučevanih visokozmogljivih napravah od meritev na HPLC predvsem odvisno od koncentracije produkta v vzorcu, umeritvenih krivulj ter od strukture rekombinantnega proteina. Med vsemi preučevanimi napravami oziroma metodami smo največje ujemanje s HPLC zabeležili pri analizatorju Octet QK. The concentration of monoclonal antibodies (mAbs) and fusion proteins can be determined by various bioanalytical methods and devices. Among these, affinity high-performance liquid chromatography (HPLC) is considered as the gold standard. As obtaining HPLC results can be very time-consuming, many high-performance alternatives have started to appear on the market. These include the Cedex family of analysers, where product concentration measurements are based on immunoturbidimetry, Octet analysis systems, which are based on bio-layer interferometry, and ValitaTiter IgG quantification assay, which detects changes in light polarization. The purpose of the master’s thesis was to investigate possible discrepancies in measurements between the before-mentioned high-throughput alternatives and HPLC. In addition, we wanted to check whether the separation of the product from larger impurities and whether the freezing of samples affects the measurements of Cedex Bio HT devices. To study the potential influence of recombinant protein molecule structures on device measurements, four CHO cell lines producing IgG1, IgG2, IgG4, and Fc-fusion protein were included in the experiment. During the 14-day production phase, daily sampling of bioprocess slurries took place. We found that the primary separation process and the freezing of the samples prior to analysis does not affect product concentration measurements and that deviations between measurements mainly depend on product concentration, calibration curves, and the structure of the recombinant protein. Among all studied devices or methods, the lowest discrepancies from HPLC were observed on the Octet QK analyser.
- Published
- 2022
15. Compressive fatigue characteristics of octet-truss lattices in different orientations
- Author
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Martyn J Pavier, Harry Coules, and Yifan Li
- Subjects
Materials science ,Condensed matter physics ,Octet ,High Energy Physics::Lattice ,Mechanical Engineering ,General Mathematics ,Nuclear Theory ,High Energy Physics::Phenomenology ,Stiffness ,Truss ,Computer Science::Numerical Analysis ,Mechanics of Materials ,Lattice (order) ,Physics::Space Physics ,medicine ,Lattice materials ,Relative density ,General Materials Science ,medicine.symptom ,Civil and Structural Engineering - Abstract
Octet-truss lattice materials have excellent potential for use as lightweight structures due to their high strength and stiffness, but low relative density. Octet-truss lattice specimens fabricated...
- Published
- 2021
- Full Text
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16. Machine learning assisted design of new lattice core for sandwich structures with superior load carrying capacity
- Author
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Adithya Challapalli and Guoqiang Li
- Subjects
Multidisciplinary ,Materials science ,Octet ,business.industry ,Mathematics and computing ,Science ,Bending ,Machine learning ,computer.software_genre ,Article ,Engineering ,Flexural strength ,Buckling ,Lattice (order) ,Representative elementary volume ,Tetrahedron ,Medicine ,Artificial intelligence ,Cube ,business ,computer - Abstract
Herein new lattice unit cells with buckling load 261–308% higher than the classical octet unit cell were reported. Lattice structures have been widely used in sandwich structures as lightweight core. While stretching dominated and bending dominated cells such as octahedron, tetrahedron and octet have been designed for lightweight structures, it is plausible that other cells exist which might perform better than the existing counterparts. Machine learning technique was used to discover new optimal unit cells. An 8-node cube containing a maximum of 27 elements, which extended into an eightfold unit cell, was taken as representative volume element (RVE). Numerous possible unit cells within the RVE were generated using permutations and combinations through MATLAB coding. Uniaxial compression tests using ANSYS were performed to form a dataset, which was used to train machine learning algorithms and form predictive model. The model was then used to further optimize the unit cells. A total of 20 optimal symmetric unit cells were predicted which showed 51–57% higher capacity than octet cell. Particularly, if the solid rods were replaced by porous biomimetic rods, an additional 130–160% increase in buckling resistance was achieved. Sandwich structures made of these 3D printed optimal symmetric unit cells showed 13–35% higher flexural strength than octet cell cored counterpart. This study opens up new opportunities to design high-performance sandwich structures.
- Published
- 2021
17. The axion-baryon coupling in SU(3) heavy baryon chiral perturbation theory
- Author
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Feng-Kun Guo, Thomas Vonk, and Ulf-G. Meißner
- Subjects
High Energy Physics - Theory ,Nuclear and High Energy Physics ,Particle physics ,Nuclear Theory ,Heavy baryon chiral perturbation theory ,Octet ,High Energy Physics::Lattice ,FOS: Physical sciences ,QC770-798 ,Nuclear Theory (nucl-th) ,High Energy Physics - Lattice ,High Energy Physics - Phenomenology (hep-ph) ,Nuclear and particle physics. Atomic energy. Radioactivity ,ddc:530 ,Nuclear Experiment ,Axion ,Physics ,High Energy Physics - Lattice (hep-lat) ,High Energy Physics::Phenomenology ,Hyperon ,Effective Field Theories ,Nuclear matter ,Cosmology of Theories beyond the SM ,Symmetry (physics) ,Baryon ,High Energy Physics - Phenomenology ,Neutron star ,High Energy Physics - Theory (hep-th) ,Chiral Lagrangians - Abstract
In the past, the axion-nucleon coupling has been calculated in the framework of SU(2) heavy baryon chiral perturbation theory up to third order in the chiral power counting. Here, we extend these earlier studies to the case of heavy baryon chiral perturbation theory with SU(3) flavor symmetry and derive the axion coupling to the full SU(3) baryon octet, showing that the axion also significantly couples to hyperons. As studies on dense nuclear matter suggest the possible existence of hyperons in stellar objects such as neutron stars, our results should have phenomenological implications related to the so-called axion window., Comment: 45 pages, 1 figure
- Published
- 2021
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18. Photoproduction of the J/ψ-pair at the LHC with Forward Detector Acceptances
- Author
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Li Gang, Song Mao, Li Ming, Guo Jian-You, and Zhang Yu
- Subjects
Scattering cross-section ,Physics ,Particle physics ,Large Hadron Collider ,Muon ,Physics and Astronomy (miscellaneous) ,Octet ,General Mathematics ,Transverse momentum ,Detector ,Rapidity ,Fock space - Abstract
LHC provides a chance to study the physical processes of γγ collision and γ p collision mode by adding a forward detector. In this paper, we investigate J/ψ-pair photoproduction in NRQCD framework at the LHC with γγ collision mode. We calculate the contributions from ${~}^{3}S_{1}^{1}$ , ${~}^{3}S_{1}^{(8)}$ , ${{~}^{1}}S_{0}^{(8)}$ , ${~}^{3}P_{J}^{(8)}$ Fock states, and find that contribution from the colour octet ${{~}^{1}}{S_{0}^{8}}$ ${~}^{3}P_{J}^{(8)}$ and ${~}^{3} P_{J}^{(8)}{~}^{3}P_{J}^{(8)}$ channels dominates this process with forward detector acceptance 0.0015 < ξ
- Published
- 2021
- Full Text
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19. Designing binding kinetic assay on the bio-layer interferometry (BLI) biosensor to characterize antibody-antigen interactions.
- Author
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Kamat, Vishal and Rafique, Ashique
- Subjects
- *
ANTIGEN-antibody reactions , *BIOSENSORS , *INTERFEROMETRY , *MONOCLONAL antibodies , *SURFACE plasmon resonance - Abstract
The Octet biosensors provide a high-throughput alternative to the well-established surface plasmon resonance (SPR) and SPR imaging (SPRi) biosensors to characterize antibody-antigen interactions. However, the utility of the Octet biosensors for accurate and reproducible measurement of binding rate constants of monoclonal antibodies (mAbs) is limited due to challenges such as analyte rebinding, and mass transport limitation (MTL). This study focuses on addressing these challenges and provides experimental conditions to reliably measure kinetics of mAb-antigen interactions. The mAb capture density of less than 0.6 nm was found to be optimal to measure a wide range of binding affinities on Octet HTX biosensor. The titration kinetic and single cycle kinetic assays performed on Octet HTX generated reproducible binding kinetic parameters and correlated with the values measured on Biacore 4000 and MASS-1. Kinetic assays performed on 0.1 nm density mAb surfaces significantly reduced MTL and enabled characterization of picomolar affinity mAbs. Finally, kinetic analysis performed on 150 antibodies to 10 antigens with molecular weights ranging from 21kD to 105kD showed concordance between Octet HTX, Biacore 4000 and MASS-1 (R 2 > 0.90). The data presented in this study suggest that under optimal experimental conditions, Octet biosensor is capable of generating kinetic values comparable to SPR/SPRi biosensors. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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20. An approach for liposome immobilization using sterically stabilized micelles (SSMs) as a precursor for bio-layer interferometry-based interaction studies.
- Author
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Wallner, Jakob, Lhota, Gabriele, Schosserer, Markus, and Vorauer-Uhl, Karola
- Subjects
- *
LIPOSOMES , *MICELLES , *INTERFEROMETRY , *BIOSENSORS , *CYTOCHROME c - Abstract
Non-fluidic bio-layer interferometry (BLI) has rapidly become a standard tool for monitoring almost all biomolecular interactions in a label-free, real-time and high-throughput manner. High-efficiency screening methods which measure the kinetics of liposomes with a variety of compounds require the immobilization of liposomes. In this work, a method is described for immobilizing liposomes for interaction studies, based on the biophysical principles of this biosensor platform. The immobilization approach includes the loading of DSPE-PEG (2000) -biotin containing sterically stabilized micelles (SSMs) which are restructured in a buffer change step, resulting in an accessible substrate for liposome immobilization. Liposomes in a concentration of 5 mM of varying composition and fluidity were immobilized on the sensor surface by inserting the hydrophobic residues of the former loaded SSMs. This proof of principle was carried out using Cytochrome C as a membrane-interacting model protein. The binding of Cytochrome C to the immobilized liposomes was demonstrated, and the derived kinetic and affinity constants were similar to values given in the literature. In order to obtain a detailed understanding of this surface, and to show the integrity of the liposomes, confocal fluorescence microscopy was used. Images of immobilized liposomes containing calcein in the aqueous core indicated intact vesicles. A combination of this simple liposome immobilization approach, the possibility of automation on BLI systems with high throughput within an acceptable timescale and excellent reproducibility makes this assay suitable for basic research as well as for industrial and regulatory applications. [ABSTRACT FROM AUTHOR]
- Published
- 2017
- Full Text
- View/download PDF
21. Design and optimization of crashworthy components based on lattice structure configuration
- Author
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Alvian Iqbal Hanif Nasrullah, Sigit Puji Santosa, and Tatacipta Dirgantara
- Subjects
Materials science ,Octet ,High Energy Physics::Lattice ,Topology optimization ,0211 other engineering and technologies ,020101 civil engineering ,02 engineering and technology ,Building and Construction ,Crystal structure ,Molecular physics ,0201 civil engineering ,Rhombic dodecahedron ,Honeycomb structure ,Lattice (order) ,021105 building & construction ,Architecture ,Tetrahedron ,Rhombicuboctahedron ,Safety, Risk, Reliability and Quality ,Civil and Structural Engineering - Abstract
Designing crashworthy components requires a special structural configuration that provides effective crushing deformation to absorb crash impact energy. Recent developments in crash impact energy absorption for crashworthy components include thin wall structures, honeycomb structures, and metallic foam sandwich structures. The honeycomb and metallic foam structures appear to have high specific energy absorption capability. However, both structural configurations have a shortcoming, i.e. honeycomb structures only have the unidirectional capability, while the metallic foam structures have highly irregular (random) three-dimensional cell configuration. The advanced development of additive manufacturing has paved the way for the developments of complicated geometry that will support the development of crashworthy components in the form of lattice structures. The lattice structures provide both three-dimensional and regular structural configurations that are able to absorb crash impact energy efficiently. Therefore, lattice structures have excellent potential to be used for energy management of crash impact structures. Eleven types of lattice configurations were examined to determine the highest specific energy absorption capability, i.e. kagome, tetrahedron, pyramid, cube, truncated-pyramid, octahedron, rhombicuboctahedron, rhombic dodecahedron, open-cell, and octet lattice structures. Numerical analysis and design optimization were performed on a single cell unit of each lattice configuration. It was found that the optimum lattice configuration for crashworthy components was the octet lattice structure. Further topology optimization of the octet lattice configuration resulted in an optimum solution of the octet structure in the form of a twisted octet lattice structure. The twisted lattice structure with 20% relative density was able to generate the highest specific energy absorption. A case study on an aircraft subfloor surface structures showed that the twisted lattice structure was able to absorb aircraft grounding impact energy efficiently. General buckling failure in the twisted lattice structure can be avoided by using a tapered configuration. This tapered lattice structure has a high potential to provide specific energy absorption of up to 127 kJ/kg. These results show the potential applicability of the lattice structure for aircraft crashworthy components.
- Published
- 2020
- Full Text
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22. Density Functional Theoretical Study on the Electronic Structure of Rh2O7+ with Low Oxidation States
- Author
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Yanying Zhao and Yaping Quan
- Subjects
Materials science ,Octet ,General Chemical Engineering ,chemistry.chemical_element ,General Chemistry ,Electronic structure ,Mass spectrometry ,Oxygen ,Lower energy ,Article ,Rhodium ,Crystallography ,Chemistry ,chemistry ,Density functional theory ,QD1-999 - Abstract
Rh2O n + (n = 2-10) species are prepared by the reaction of the laser-ablated rhodium atoms with oxygen; furthermore, they are characterized by employing time-of-flight mass spectroscopy. To reveal the stable electronic structure, in this study, we performed the density functional theory calculations for the possible isomers of Rh2O7 +. A total of 29 geometries were obtained including cyclic Rh2O3, cyclic Rh2O2, and ring-opening structures with doublet, quartet, sextet, and octet states. It is noteworthy that no Rh-Rh bond was observed for all the optimized Rh2O7 + isomers including oxides, peroxides, superoxides, and oxygen groups. The optimized geometries were also confirmed to exhibit minimum structural energies by employing harmonic frequency analysis at the same energy level. Generally, two types of oxygen-bridged geometries were discovered with cyclic and pseudo-linear Rh2O7 +, which contained one or more than one O2 groups. It is concluded that the cyclic structure comprises a lower energy than that observed in pseudo-linear structures. In addition, Rh2O7 + tends to be unstable when the coordination groups change from O2 to O2 - unit. Finally, the localized orbital bonding analysis indicates that Rh has oxidation states of 1 or 2 in cyclic Rh2O7 + structures; this is true even in the presence of O2-, O2 -, and O2 2- groups.
- Published
- 2020
23. Experimental and numerical investigation of selective laser melting–induced defects in Ti–6Al–4V octet truss lattice material: the role of material microstructure and morphological variations
- Author
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Lu Liu, Meisam Asgari, Damiano Pasini, Asma El Elmi, and David Melancon
- Subjects
Work (thermodynamics) ,Materials science ,Octet ,Atomic force microscopy ,Mechanical Engineering ,Truss ,02 engineering and technology ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,Microstructure ,020303 mechanical engineering & transports ,0203 mechanical engineering ,Mechanics of Materials ,Lattice materials ,General Materials Science ,Ti 6al 4v ,Selective laser melting ,Composite material ,0210 nano-technology - Abstract
The remarkable progress in additive manufacturing has promoted the design of architected materials with mechanical properties that go beyond those of conventional solids. Their realization, however, leads to architectures with process-induced defects that can jeopardize mechanical and functional performance. In this work, we investigate experimentally and numerically as-manufactured defects in Ti–6Al–4V octet truss lattice materials fabricated with selective laser melting. Four sets of as-manufactured defects, including surface, microstructural, morphological, and material property imperfections, are characterized experimentally at given locations and orientations. Within the characterized defects, material property and morphological defects are quantified statistically using a combination of atomic force microscopy and micro–computed tomography to generate representative models that incorporate individual defects and their combination. The models are used to assess the sensitivity to as-manufactured defects. Then, the study is expanded by tuning defects amplitude to elucidate the role of the magnitude of as-designed defects on the mechanical properties of the lattice material.
- Published
- 2020
- Full Text
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24. Continuum model for effective properties of orthotropic octet-truss lattice through additive manufacturing
- Author
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Adithya Challapalli
- Subjects
Materials science ,Octet ,Continuum (measurement) ,Constitutive equation ,Computational Mechanics ,Truss ,02 engineering and technology ,Orthotropic material ,01 natural sciences ,010101 applied mathematics ,Specific strength ,Computational Mathematics ,020303 mechanical engineering & transports ,0203 mechanical engineering ,Lattice (order) ,Lattice materials ,0101 mathematics ,Composite material - Abstract
Cellular materials, often called lattice materials, are increasingly receiving attention for their ultralight structures with high specific strength, excellent impact absorption, acoustic i...
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- 2020
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25. Peculiar bond characters of fivefold coordinated octet compound crystals
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Shang-Peng Gao, An-An Sun, and Gong Gu
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Wannier function ,Materials science ,Octet ,Graphene ,Context (language use) ,02 engineering and technology ,General Chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,law.invention ,Chemistry ,Delocalized electron ,Chemical bond ,Atomic orbital ,Chemical physics ,law ,0103 physical sciences ,Monolayer ,010306 general physics ,0210 nano-technology - Abstract
The present work exemplifies complementary perspectives offered by the band and bond pictures of solids, with an emphasis on the chemical intuition pertaining to the latter, especially in the presence of interfaces. The modern computational method of constructing a unique set of maximally localized Wannier functions from delocalized band states imparts new interpretations to the familiar concept of chemical bonds in the context of crystalline solids. By bridging the band and bond pictures using advanced computational tools, we reveal for the first time the unusual bond characters of a long-predicted fivefold coordinated structure of binary octet compounds ANB8−N consisting of AA′ stacked planar AB honeycombs. While the isolated monolayer retains the familiar pz–π bonding in a honeycomb framework as in graphene and hexagonal boron nitride, the bulk foregoes in-plane π bonding and embraces out-of-plane ⋯A–B–A–B⋯ chain bonding via overlapping pz orbitals. Not only does the chemical intuition gained by invoking the bond picture clarify the chemical nature of the fivefold coordination, but it also facilely explains a salient discrepancy in theoretical predictions in otherwise sound ample experimental evidence in the form of epitaxial thin films, paving the way towards rational synthesis of such thin films for optoelectronic applications. On the other hand, we show that the conduction band minimum, important in determining the electrical and optical properties, is a distinctly extended state that can only be properly described within the band picture., A refreshed view of chemical bonds in solids unveils unusual bonding in fivefold coordinated bulk crystals of octet compounds: out-of-plane cation–anion chain bonding via overlapping pz orbitals replaces in-plane π bonding of the isolated monolayer.
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- 2020
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26. Probing Fractional Quantum Hall Sheets in Dense Baryonic Matter
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Rho, Mannque, Institut de Physique Théorique - UMR CNRS 3681 (IPHT), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), and HEP, INSPIRE
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[PHYS.NUCL] Physics [physics]/Nuclear Theory [nucl-th] ,Nuclear Theory ,[PHYS.NUCL]Physics [physics]/Nuclear Theory [nucl-th] ,color flavor locked phase ,Chern-Simons term ,nucleus ,anomaly ,FOS: Physical sciences ,critical phenomena ,meson ,[PHYS.HPHE] Physics [physics]/High Energy Physics - Phenomenology [hep-ph] ,baryon ,quark ,Nuclear Theory (nucl-th) ,High Energy Physics - Phenomenology ,effective field theory ,High Energy Physics - Phenomenology (hep-ph) ,star ,nuclear matter ,[PHYS.HPHE]Physics [physics]/High Energy Physics - Phenomenology [hep-ph] ,local ,fractional ,droplet ,symmetry ,octet - Abstract
Unlike the octet baryons for $N_f=3$, there is no skyrmion coming from the $\eta^\prime$ meson. It is instead described as a fractional quantum Hall droplet, a pancake or a pita involving a singular $\eta^\prime$ ring in which Chern-Simons fields live. By incorporating hidden local symmetry and hidden scale symmetry in nuclear dynamics, I describe how to access baryon-charged quantum Hall droplets in dense nuclear matter in terms of the nuclear scale-chiral effective field theory approach ``G$n$EFT" with the $U_A(1)$ anomaly taken into account. I discuss how the single-flavor baryon that I will call ${\cal B}^s$ could be exposed in superdense baryonic matter, figuring, perhaps, in ``quark stars" associated with the baryon-quark continuity involving CFL or phase transitions., Comment: 8 pages, no figures
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- 2022
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27. Evolution of global and local deformation in additively manufactured octet truss lattice structures
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Christopher Saldana, David G. Moore, and Elliott W. Jost
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Surface (mathematics) ,Fusion ,Materials science ,Octet ,business.industry ,Additive manufacturing ,Lattice structure ,Industrial engineering. Management engineering ,Process (computing) ,Truss ,Structural engineering ,T55.4-60.8 ,Compression (physics) ,Lattice (module) ,Octet truss ,Deformation (engineering) ,business ,Computed tomography - Abstract
Additively manufactured lattice truss structures, often referred to as architected cellular materials, present significant advantages over conventional structures due to their unique characteristics such as high strength-to-weight ratios and surface area-to-volume ratios. These geometrically complex structures, however, come with concomitant challenges for qualification and inspection. In this study, compression testing interrupted with micro-computed tomography inspection was conducted to monitor the evolution of global and local deformation throughout the loading process of 304 L stainless steel octet truss lattice structures. Both two- and three-dimensional image analysis techniques were leveraged to characterize geometric heterogeneities resulting from the laser powder bed fusion manufacturing process as well as track the structure throughout deformation. Variations from model-predicted behavior resulting from these heterogeneities are considered relative to the predicted and actual responses of the structures during compression to better understand, model, and predict the octet truss lattice structure compression response.
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- 2021
28. Cos(2ϕh) asymmetry in J/ψ production in unpolarized ep collision
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Mariyah Siddiqah, Asmita Mukherjee, and Raj Kishore
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Quantum chromodynamics ,Physics ,Particle physics ,Proton ,Octet ,media_common.quotation_subject ,Nuclear Theory ,High Energy Physics::Phenomenology ,Parton ,Asymmetry ,Gluon ,Distribution function ,High Energy Physics::Experiment ,Production (computer science) ,Nuclear Experiment ,media_common - Abstract
We present a calculation of the $\mathrm{cos}(2{\ensuremath{\phi}}_{h})$ asymmetry in $J/\ensuremath{\psi}$ production in electron-proton collisions at the future electron-ion collider (EIC), a useful channel to probe the transverse momentum dependent gluon distribution functions also known as gluon transverse momentum dependent parton distributions (TMDs). The dominant subprocess for the $J/\ensuremath{\psi}$ production is the virtual-photon-gluon fusion process ${\ensuremath{\gamma}}^{*}+g\ensuremath{\rightarrow}J/\ensuremath{\psi}+g$. The production of $J/\ensuremath{\psi}$ is calculated in the nonrelativistic quantum chromodynamics framework with the inclusion of both color singlet and color octet contributions. Numerical estimates of the $\mathrm{cos}(2{\ensuremath{\phi}}_{h})$ asymmetry are given in the kinematical region to be accessed by the future EIC. The asymmetry depends on the parametrization of the gluon TMDs, as well as on the long distance matrix elements. We use both Gaussian-type parametrization and the McLerran-Venugopalan model for the TMDs in the kinematical region of small $x$, where the gluons play a dominant role. The asymmetry may be useful to probe the ratio of the linearly-polarized and the unpolarized gluon distribution in the proton.
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- 2021
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29. Single-parameter mechanical design of a 3D-printed octet truss topological scaffold to match natural cancellous bones
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Feipeng Zhu, Zhiyong Li, Qiang Chen, Luping Wang, Qiwei Li, and Prasad Yarlagadda
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Scaffold ,Materials science ,3D-printing ,Octet ,Modulus ,Truss ,Young's modulus ,02 engineering and technology ,Topology ,03 medical and health sciences ,symbols.namesake ,Mathematical model ,General Materials Science ,Young’s modulus ,Porosity ,Bone regeneration ,Materials of engineering and construction. Mechanics of materials ,030304 developmental biology ,0303 health sciences ,Mechanical Engineering ,021001 nanoscience & nanotechnology ,Structure design ,Finite element method ,3. Good health ,Mechanics of Materials ,Cellular solid ,symbols ,TA401-492 ,Strength ,0210 nano-technology - Abstract
Designing a suitable scaffold matching the mechanical properties of natural bones to optimize the bone regeneration is required in bone tissue engineering. The present work developed a single-parameter design method for the octet truss topological scaffold to achieve the accurate prediction and flexible adjustment of its Young’s modulus and strength. A theoretical model that formulated the normalized Young’s modulus and normalized yield strength of the octet truss scaffold by the single parameter (d/O) was proposed and further validated by uniaxial compression tests and FEA simulations. On the basis of the proposed model, the Young's modulus and yield strength of the octet truss scaffold made of different polymers with different d/O were mapped, and the ranges of suitable d/O that match the different natural cancellous bones were suggested. The results showed that the design method could accurately predict the porosity, specific area, normalized Young’s modulus and normalized yield strength, and adjust the mechanical properties of the scaffold in a wide range. The present work can be used for the design of scaffolds and the selection of constituent materials to obtain a suitable scaffold with desired mechanical properties, and has application prospects in the fields of bone tissue engineering and regenerative medicine.
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- 2021
30. Comparison of biosensor platforms in the evaluation of high affinity antibody-antigen binding kinetics.
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Yang, Danlin, Singh, Ajit, Wu, Helen, and Kroe-Barrett, Rachel
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- *
BIOSENSORS , *IMMUNE complexes , *CHEMICAL affinity , *DRUG development , *MONOCLONAL antibodies , *LIQUID chromatography - Abstract
The acquisition of reliable kinetic parameters for the characterization of biomolecular interactions is an important component of the drug discovery and development process. While several benchmark studies have explored the variability of kinetic rate constants obtained from multiple laboratories and biosensors, a direct comparison of these instruments' performance has not been undertaken, and systematic factors contributing to data variability from these systems have not been discussed. To address these questions, a panel of ten high-affinity monoclonal antibodies was simultaneously evaluated for their binding kinetics against the same antigen on four biosensor platforms: GE Healthcare's Biacore T100, Bio-Rad's ProteOn XPR36, ForteBio's Octet RED384, and Wasatch Microfluidics's IBIS MX96. We compared the strengths and weaknesses of these systems and found that despite certain inherent systematic limitations in instrumentation, the rank orders of both the association and dissociation rate constants were highly correlated between these instruments. Our results also revealed a trade-off between data reliability and sample throughput. Biacore T100, followed by ProteOn XPR36, exhibited excellent data quality and consistency, whereas Octet RED384 and IBIS MX96 demonstrated high flexibility and throughput with compromises in data accuracy and reproducibility. Our results support the need for a “fit-for-purpose” approach in instrument selection for biosensor studies. [ABSTRACT FROM AUTHOR]
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- 2016
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31. A biolayer interferometry-based assay for rapid and highly sensitive detection of biowarfare agents.
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Mechaly, Adva, Cohen, Hila, Cohen, Ofer, and Mazor, Ohad
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- *
INTERFEROMETRY , *BIOLOGICAL warfare , *OPTICAL sensors , *PROTEIN-protein interactions , *IMMUNOASSAY - Abstract
Biolayer interferometry (BLI) is an optical technique that uses fiber-optic biosensors for label-free real-time monitoring of protein–protein interactions. In this study, we coupled the advantages of the Octet Red BLI system (automation, fluidics-free, and on-line monitoring) with a signal enhancement step and developed a rapid and sensitive immunological-based method for detection of biowarfare agents. As a proof of concept, we chose to demonstrate the efficacy of this novel assay for the detection of agents representing two classes of biothreats, proteinaceous toxins, and bacterial pathogens: ricin, a lethal plant toxin, and the gram-negative bacterium Francisella tularensis , the causative agent of tularemia. The assay setup consisted of biotinylated antibodies immobilized to the biosensor coupled with alkaline phosphatase-labeled antibodies as the detection moiety to create nonsoluble substrate crystals that precipitate on the sensor surface, thereby inducing a significant wavelength interference. It was found that this BLI-based assay enables sensitive detection of these pathogens (detection limits of 10 pg/ml and 1 × 10 4 pfu/ml ricin and F. tularensis , respectively) within a very short time frame (17 min). Owing to its simplicity, this assay can be easily adapted to detect other analytes in general, and biowarfare agents in particular, in a rapid and sensitive manner. [ABSTRACT FROM AUTHOR]
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- 2016
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32. Design of Hierarchical Architected Lattices for Enhanced Energy Absorption
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Alok Sutradhar and Mohamad Al Nashar
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Technology ,Materials science ,Octet ,High Energy Physics::Lattice ,Molecular physics ,Article ,Dodecahedron ,Truncated octahedron ,Lattice (order) ,General Materials Science ,energy absorption ,Elastic modulus ,Microscopy ,QC120-168.85 ,Range (particle radiation) ,QH201-278.5 ,Metamaterial ,Engineering (General). Civil engineering (General) ,simulation ,Finite element method ,TK1-9971 ,hierarchical structures ,Descriptive and experimental mechanics ,lattices ,architected materials ,Electrical engineering. Electronics. Nuclear engineering ,TA1-2040 - Abstract
Hierarchical lattices are structures composed of self-similar or dissimilar architected metamaterials that span multiple length scales. Hierarchical lattices have superior and tunable properties when compared to conventional lattices, and thus, open the door for a wide range of material property manipulation and optimization. Using finite element analysis, we investigate the energy absorption capabilities of 3D hierarchical lattices for various unit cells under low strain rates and loads. In this study, we use fused deposition modeling (FDM) 3D printing to fabricate a dog bone specimen and extract the mechanical properties of thermoplastic polyurethane (TPU) 85A with a hundred percent infill printed along the direction of tensile loading. With the numerical results, we observed that the energy absorption performance of the octet lattice can be enhanced four to five times by introducing a hierarchy in the structure. Conventional energy absorption structures such as foams and lattices have demonstrated their effectiveness and strengths, this research aims at expanding the design domain of energy absorption structures by exploiting 3D hierarchical lattices. The result of introducing a hierarchy to a lattice on the energy absorption performance is investigated by varying the hierarchical order from a first-order octet to a second-order octet. In addition, the effect of relative density on the energy absorption is isolated by creating a comparison between a first-order octet lattice with an equivalent relative density as a second-order octet lattice. The compression behaviors for the second order octet, dodecahedron, and truncated octahedron are studied. The effect of changing the cross-sectional geometry of the lattice members with respect to the energy absorption performance is investigated. Changing the orientation of the second-order cells from 0 to 45 degrees has a considerable impact on the force–displacement curve, providing a 20% increase in energy absorption for the second-order octet. Analytical solutions of the effective elasticity modulus for the first- and second-order octet lattices are compared to validate the simulations. The findings of this paper and the provided understanding will aid future works in lattice design optimization for energy absorption.
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- 2021
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33. A Study of J/$\psi$ Decays into baryon-antibaryon pairs
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Nikolai Kivel
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Quantum chromodynamics ,Baryon ,Physics ,Particle physics ,Amplitude ,Factorization ,Octet ,High Energy Physics::Phenomenology ,Effective field theory ,High Energy Physics::Experiment ,Observable ,Twist - Abstract
We perform an analysis of $J/\psi$ decays into octet baryons using the QCD factorisation framework. All decay amplitudes are calculated within the effective field theory approach. The subleading amplitude, which describes the decay of longitudinally polarised charmonia, is obtained for the first time using higher twist three-quark distribution amplitudes. A qualitative analysis of the experimental data is performed. It is found that the polarisation parameter $\alpha_B$ can be described with an accuracy $10-30\%$, which indicates that the pQCD contribution provides the dominant part for this observable.
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- 2021
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34. The Musical-Acoustical Development of the Violin Octet
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Carleen M. Hutchins
- Subjects
Violin ,Octet ,media_common.quotation_subject ,Musical ,Art ,Visual arts ,media_common - Published
- 2021
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35. Inertial focusing and zeta potential measurements of single-nanoparticles using octet-nanochannels
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Shohei Kishimoto, Kazumichi Yokota, Makusu Tsutsui, and Masateru Taniguchi
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Physics ,Electrophoresis ,Ions ,Resistive touchscreen ,Inertial frame of reference ,Octet ,Biomedical Engineering ,Degrees of freedom (statistics) ,Bioengineering ,02 engineering and technology ,General Chemistry ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,Biochemistry ,Molecular physics ,0104 chemical sciences ,Pulse (physics) ,Exponential function ,Ion ,Zeta potential ,Nanoparticles ,0210 nano-technology - Abstract
Capture-to-translocation dynamics control is an important issue for single-particle and -molecule analyses by resistive pulse waveforms. Here, we report on regulated motions for accurate zeta-potential assessments of single nanoscale objects passing through an octet-nanochannel. We observed ionic spike signals consisting of eight consecutive sub-pulses signifying the ion blockage at the eight sensing zones in series upon electrophoretic translocation of individual nanoparticles. We find an exponential decrease to saturation of the channel-to-channel translocation duration as a nanobead moves forward, reflecting the more restricted radial motion degrees of freedom via inertial effects at the downstream side of the octet channel. This finding enabled a protocol for single-nanoparticle zeta potential estimation impervious to the uncertainty stemming from the stochastic nature of the translocation dynamics. The multi-channel approach presented in this study may be used as a useful tool for analyzing particles and molecules of variable sizes.
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- 2021
36. A New Look on Octet‐Compliant Macrocyclic Organoaluminum Carboxylates as Dormant Poly‐Lewis Acids
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Daniel Prochowicz, Iwona Justyniak, Janusz Lewiński, and Michał Terlecki
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Inorganic Chemistry ,Octet ,Chemistry ,Polymer chemistry ,Supramolecular chemistry ,Lewis acids and bases - Published
- 2019
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37. A fuzzy optimization method for octet-truss lattices
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Libin Zhao, Meijuan Shan, Yunhui Yang, Jianyu Zhang, and Dexuan Qi
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Normalization (statistics) ,Octet ,Mechanical Engineering ,Isotropy ,Process (computing) ,Truss ,02 engineering and technology ,01 natural sciences ,Fuzzy logic ,Industrial and Manufacturing Engineering ,010101 applied mathematics ,020303 mechanical engineering & transports ,0203 mechanical engineering ,Representative elementary volume ,Applied mathematics ,0101 mathematics ,Unit (ring theory) ,Mathematics - Abstract
Purpose This paper aims to present a multiscale fuzzy optimization (FO) method to optimize both the density distribution and macrotopology of a uniform octet-truss lattice structure. Design/methodology/approach The design formulae for the strut radii are presented based on the effective mechanical properties obtained from the representative volume element. The proposed basic lattice material is applied in a normalization process to determine the material model with penalization. The solid isotropic material with penalization (SIMP) method is extended to solve the minimum compliance problem using the optimality criteria. The evolutionary deletion process is proposed to delete elements corresponding to thin-strut unit cells and to obtain the optimal macrotopology. Findings Both numerical cases indicate that the FO results significantly improved in structural performance compared with the results of the conventional SIMP. The deleting threshold controls the macrotopology of the graded-density lattice structures with negligible effects on the mechanical properties. Originality/value This paper presents one of the first multiscale optimization methods to optimize both the relative density and macrotopology of uniform octet-truss lattices. The material model and corresponding optimality criteria of octet-truss lattices are proposed and implemented in the optimization.
- Published
- 2019
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38. Systematic Procedure for Drawing Lewis Structures Based on Electron Pairing Priority and the Explicit Use of Donor Bonds: An Alternative to the Normal Procedure Which Can Be Pen and Paper Based or Automated on a PC in User Interactive 3D
- Author
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Patrick McArdle
- Subjects
Electron pair ,Octet ,010405 organic chemistry ,05 social sciences ,050301 education ,General Chemistry ,01 natural sciences ,0104 chemical sciences ,Education ,Lewis structure ,Theoretical physics ,symbols.namesake ,Oxidation state ,Covalent bond ,Pairing ,symbols ,Octet rule ,Valence electron ,0503 education - Abstract
This article contrasts the normal method for drawing Lewis structures with a two-step systematic approach. The latter approach uses a known molecular connectivity and a knowledge of the number of valence electrons that each atom possesses to visualize bonds that are formed by pairing electrons, one from each atom. This process is repeated until at least one of the non-hydrogen atoms in each bond has an octet. Donor bonds are added when atoms with six and eight electrons are adjacent. In forming donor bonds charges are added to the atoms involved to maintain electron accounting and there is no need to use a formula to calculate formal charges. The general importance of adhering to the octet rule for p-block compounds is stressed and the difference between covalent and donor bonds and the use of the recent IUPAC definition of oxidation state which is based on Lewis structures is included in the discussion. When students are able to draw Lewis structures they can be given access to PC software, available on an academic free basis, which will draw rotatable Lewis structures in 3D for p-block compounds. The software allows the user to move electron pairs in a bow and arrow fashion within the structures and atoms are highlighted when the octet is exceeded.
- Published
- 2019
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- View/download PDF
39. Semileptonic decays of anti-triplet charmed baryons
- Author
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Chia-Wei Liu, Chao-Qiang Geng, Shu-Wei Yeh, and Tien-Hsueh Tsai
- Subjects
Physics ,Quark ,Nuclear and High Energy Physics ,Particle physics ,Octet ,010308 nuclear & particles physics ,media_common.quotation_subject ,FOS: Physical sciences ,01 natural sciences ,Asymmetry ,Helicity ,lcsh:QC1-999 ,High Energy Physics - Experiment ,Baryon ,Charmed baryons ,Formalism (philosophy of mathematics) ,High Energy Physics - Experiment (hep-ex) ,High Energy Physics - Phenomenology ,High Energy Physics - Phenomenology (hep-ph) ,0103 physical sciences ,010306 general physics ,lcsh:Physics ,media_common - Abstract
We study the semileptonic decays ${\bf B_c} \to {\bf B_n} \ell^+ \nu_{\ell}$ where ${\bf B_{c(n)}}$ is the anti-triplet-charmed (octet) baryon with the $SU(3)_f$ flavor symmetry and helicity formalism. In particular, we present the decay branching ratios of $ {\bf B_c} \to {\bf B_n}\ell^+ \nu_\ell$ in three scenarios: (a) an exact $SU(3)_f$ symmetry with equal masses for the anti-triplet-charmed (octet) baryon states of ${\bf B_c}$ (${\bf B_n}$), (b) $SU(3)_f$ parameters without the baryonic momentum-transfer dependence, and (c) $SU(3)_f$ with baryonic transition form factors in the heavy quark limit. We show that our results are all consistent with the existing data. Explicitly, we predict that ${\cal B}( \Xi_c^+ \to \Xi^0 e^+ \nu_{e})=(11.9\pm1.3, 9.8\pm 1.1, 10.7\pm 0.9)\times 10^{-2}$ and ${\cal B}( \Xi_c^0 \to \Xi^- e^+ \nu_{e})=(3.0\pm0.3, 2.4\pm 0.3, 2.7\pm 0.2)\times 10^{-2}$ in the scenarios (a), (b) and (c) agree with the data of $(14.0^{+8.3}_{-8.7})\times 10^{-2}$ and $(5.6\pm2.6)\times 10^{-2}$ from the CLEO Collaboration, respectively. In addition, we obtain that ${\cal B}(\Lambda_c^+\to n e^+ \nu_e)=(2.8\pm 0.4, 4.9\pm0.4, 5.1\pm0.4)\times 10^{-3}$ in (a), (b) and (c). We also examine the longitudinal asymmetry parameters of $\alpha({\bf B_c} \to {\bf B_n} \ell^+ \nu_{\ell})$, which are sensitive to the different scenarios with $SU(3)_f$. Some of the decay branching ratios and asymmetries can be observed by the ongoing experiments at BESIII and LHCb as well as the future searches by BELLEII., Comment: 11 pages, 1 figure, revised version accepted by PLB
- Published
- 2019
40. Singly Cabibbo suppressed decays of Λc+ with SU(3) flavor symmetry
- Author
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Chao-Qiang Geng, Tien-Hsueh Tsai, and Chia-Wei Liu
- Subjects
Physics ,Quark ,Nuclear and High Energy Physics ,Particle physics ,Octet ,Meson ,010308 nuclear & particles physics ,High Energy Physics::Phenomenology ,01 natural sciences ,Baryon ,Charmed baryons ,0103 physical sciences ,High Energy Physics::Experiment ,010306 general physics ,Flavor - Abstract
We analyze the weak processes of anti-triplet charmed baryons decaying to octet baryons and mesons with the SU(3) flavor symmetry and topological quark diagram scheme. We study the decay branching ratios without neglecting the contributions from O ( 15 ‾ ) for the first time in the SU(3) flavor symmetry approach. The fitting results for the Cabibbo allowed and suppressed decays of Λ c + are all consistent with the experimental data. We predict all singly Cabibbo suppressed decays. In particular, we find that B ( Λ c + → p π 0 ) = ( 1.3 ± 0.7 ) × 10 − 4 , which is slightly below the current experimental upper limit of 2.7 × 10 − 4 and can be tested by the ongoing experiment at BESIII as well as the future one at Belle-II.
- Published
- 2019
- Full Text
- View/download PDF
41. Fluid flow and heat transfer characteristics of octet truss lattice geometry
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Shankar Krishnan and Pawankumar Ekade
- Subjects
Materials science ,Octet ,High Energy Physics::Lattice ,020209 energy ,General Engineering ,Truss ,Geometry ,02 engineering and technology ,Metal foam ,Heat sink ,Condensed Matter Physics ,01 natural sciences ,Nusselt number ,010305 fluids & plasmas ,Thermal conductivity ,0103 physical sciences ,Heat transfer ,0202 electrical engineering, electronic engineering, information engineering ,Fluid dynamics - Abstract
Octet truss lattice structures are a potential candidate for developing multifunctional heat exchangers/sinks owing to their superior structural characteristics compared against stochastic open-cellular metal foams. Structural efficiency is achieved primarily due to increased nodal connectivity in octet-truss lattices. Designed octet trusses and periodic cellular materials, in general, lend themselves well to topology optimization and integration of multiple functions enabling a high degree of tailorability and superior performance benefits. Specific to heat transfer design, octet truss lattices can be tailored to achieve optimal strand cross-sectional area-to-length ratio for improved effective thermal conductivity while meeting surface-area per volume requirements for convective transport. In this work, we explore the heat and fluid flow characteristics using direct numerical simulations of a periodic unit-cell. Effective thermal conductivity, permeability, inertial coefficient, friction factor and Nusselt number for octet truss lattice structures are predicted and compared against stochastic foam experimental data. A range of porosities and pore densities are simulated and heat transfer and fluid flow characteristics are correlated using a single length scale in the form of Brinkman screening length, √K, as against existing literature where different geometric length scales are used. Further, octet truss lattice geometry is compared against existing stochastic metal foam heat and fluid flow empirical data. Normalized permeability of octet lattices were found to be 20–80% higher than stochastic foam for a given porosity. Similarly, for a fixed porosity, inertial coefficients of octet lattices were 50% of stochastic experimental measurements. For the range of Reynolds number considered, octet truss lattices show similar fluid and heat flow characteristics if not better performance than stochastic foams and thus making them ideally suited for tailored multifunctional heat sinks and exchangers.
- Published
- 2019
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42. Baryon axial vector current in large- Nc chiral perturbation theory: Complete analysis for Nc=3
- Author
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Rubén Flores-Mendieta, Johann Hernandez, and Carlos Isaac Garcia
- Subjects
Quark ,Physics ,Chiral perturbation theory ,Heavy baryon chiral perturbation theory ,Octet ,010308 nuclear & particles physics ,High Energy Physics::Lattice ,Nuclear Theory ,High Energy Physics::Phenomenology ,Order (ring theory) ,01 natural sciences ,Baryon ,0103 physical sciences ,010306 general physics ,Pseudovector ,Mathematical physics ,Free parameter - Abstract
The baryon axial vector current is computed in heavy baryon chiral perturbation theory in the large-${N}_{c}$ limit, where ${N}_{c}$ is the number of color charges. One-loop nonanalytic corrections of the order ${m}_{q}\mathrm{ln}{m}_{q}$ are comprised in the analysis, with contributions of both intermediate octet and decuplet baryon states, to all orders in the $1/{N}_{c}$ expansion of the axial vector current relevant for ${N}_{c}=3$. Theoretical expressions are obtained in the limit of vanishing decuplet-octet mass difference only, which allows one to carry out a full comparison with conventional heavy baryon chiral perturbation theory results for three flavors of light quarks and at the physical value ${N}_{c}=3$. Both approaches perfectly agree to all orders considered. Furthermore, a numerical analysis via a least-squares fit is performed in order to extract the values of the free parameters of the theory, using the experimental data available. The predictions of formalism are in good agreement with the experimental data.
- Published
- 2021
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- View/download PDF
43. Octet and decuplet baryon self-energies in relativistic SU(3) chiral effective theory
- Author
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Chueng-Ryong Ji, Wolodymyr Melnitchouk, and P. M. Copeland
- Subjects
Physics ,Particle physics ,Nuclear Theory ,Meson ,Octet ,010308 nuclear & particles physics ,High Energy Physics::Lattice ,Lorentz transformation ,High Energy Physics::Phenomenology ,FOS: Physical sciences ,01 natural sciences ,Nuclear Theory (nucl-th) ,Baryon ,High Energy Physics - Phenomenology ,Dipole ,symbols.namesake ,High Energy Physics - Phenomenology (hep-ph) ,Regularization (physics) ,0103 physical sciences ,Effective field theory ,symbols ,Gauge theory ,Nuclear Experiment ,010306 general physics - Abstract
The self-energies of the full set of flavor SU(3) octet and decuplet baryons are computed within a relativistic chiral effective theory framework. The leading nonanalytic chiral behavior is derived for the octet and decuplet masses, and a finite-range regularization consistent with Lorentz and gauge invariance is applied to account for the finite size of the baryons. Using a four-dimensional dipole form factor, the relative importance of various meson-baryon loop contributions to the self-energies is studied numerically as a function of the dipole range parameter and meson mass, and comparison is made between the relativistic results and earlier approximations within the heavy baryon limit., 42 pages, 7 figures
- Published
- 2021
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- View/download PDF
44. Color-octet scalars in Dirac gaugino models with broken R symmetry
- Author
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Linda M. Carpenter and Taylor Murphy
- Subjects
Physics ,Nuclear and High Energy Physics ,Particle physics ,Large Hadron Collider ,R-symmetry ,Octet ,010308 nuclear & particles physics ,Dirac (video compression format) ,Scalar (mathematics) ,Gaugino ,FOS: Physical sciences ,QC770-798 ,01 natural sciences ,Pseudoscalar ,High Energy Physics - Phenomenology ,High Energy Physics - Phenomenology (hep-ph) ,Supersymmetry Phenomenology ,Nuclear and particle physics. Atomic energy. Radioactivity ,0103 physical sciences ,010306 general physics ,Phenomenology (particle physics) ,Phenomenological Models - Abstract
In this work we study the collider phenomenology of color-octet scalars (sgluons) in supersymmetric models with Dirac gaugino masses that feature an explicitly broken $R$ symmetry ($R$-broken models). We construct such models by augmenting minimal $R$-symmetric models with a fairly general set of supersymmetric and softly supersymmetry-breaking operators that explicitly break $R$ symmetry. We then compute the rates of all significant two-body decays and highlight new features that appear as a result of $R$ symmetry breaking, including enhancements to extant decay rates, novel tree- and loop-level decays, and improved cross sections of single sgluon production. We demonstrate in some detail how the familiar results from minimal $R$-symmetric models can be obtained by restoring $R$ symmetry. In parallel to this discussion, we explore constraints on these models from the Large Hadron Collider. We find that, in general, $R$ symmetry breaking quantitatively affects existing limits on color-octet scalars, perhaps closing loopholes for light CP-odd (pseudoscalar) sgluons while opening one for a light CP-even (scalar) particle. Qualitatively, however, we find that -- much as for minimal $R$-symmetric models, despite stark differences in phenomenology -- scenarios with broken $R$ symmetry and two sgluons below the TeV scale can be accommodated by existing searches., Comment: 69 pages, 14 figures. Updated to resemble JHEP Version of Record
- Published
- 2021
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- View/download PDF
45. The Gluon Exchange Model for diffractive and inelastic collisions
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Marek Jezabek and Andrzej Rybicki
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Nuclear and High Energy Physics ,Proton ,Octet ,Nuclear Theory ,Inelastic collision ,FOS: Physical sciences ,Baryon number transport ,Inelastic diffraction ,01 natural sciences ,Hadron-nucleus collisions ,Diquark disintegration ,Nuclear Theory (nucl-th) ,Nuclear physics ,High Energy Physics - Phenomenology (hep-ph) ,0103 physical sciences ,Neutron ,Rapidity ,010306 general physics ,Nuclear Experiment ,Physics ,010308 nuclear & particles physics ,Soft gluon exchange ,High Energy Physics::Phenomenology ,lcsh:QC1-999 ,Gluon ,Diquark ,High Energy Physics - Phenomenology ,Physics::Accelerator Physics ,High Energy Physics::Experiment ,Baryon number ,lcsh:Physics - Abstract
We propose a new model for a homogeneous description of hadron-hadron and hadron-nucleus collisions, the Gluon Exchange Model, fundamentally based on color octet (gluon) exchange. In proton-proton collisions we provide an exact description of the final state proton and neutron spectrum including the proton diffractive peak. In proton-nucleus reactions we find that the projectile proton diquark cannot survive in more than about half of multiple proton-nucleon processes and consequently must be very frequently disintegrated, leading to long transfers of baryon number over rapidity space., 10 pages, 4 figures
- Published
- 2021
46. Extracting color octet NRQCD matrix elements from J /ψ production at the EIC
- Author
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Pieter Taels, Daniël Boer, Cristian Pisano, High-Energy Frontier, Van Swinderen Institute for Particle Physics and G, Centre de Physique Théorique [Palaiseau] (CPHT), and Centre National de la Recherche Scientifique (CNRS)-École polytechnique (X)
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Particle physics ,Octet ,color: octet ,High Energy Physics::Lattice ,01 natural sciences ,heavy quark: pair production ,law.invention ,Matrix (mathematics) ,law ,0103 physical sciences ,Strong Interactions ,010306 general physics ,Collider ,Physics ,quantum chromodynamics: nonrelativistic ,010308 nuclear & particles physics ,High Energy Physics::Phenomenology ,electron nucleon: colliding beams ,Upsilon(9460): production ,eRHIC ,High Energy Physics - Phenomenology ,Pair production ,kinematics ,[PHYS.HPHE]Physics [physics]/High Energy Physics - Phenomenology [hep-ph] ,Production (computer science) ,High Energy Physics::Experiment ,J/psi(3100): production - Abstract
Recently unpolarized and polarized $J/\psi \,(\Upsilon)$ production at the Electron-Ion Collider (EIC) has been proposed as a new way to extract two poorly known color-octet NRQCD long-distance matrix elements: $\langle0\vert{\cal O}_{8}^{J/\psi}(^{1}S_{0})\vert0\rangle$ and $\langle0\vert{\cal O}_{8}^{J/\psi}(^{3}P_{0})\vert0\rangle$. The proposed method is based on a comparison to open heavy-quark pair production ideally performed at the same kinematics. In this paper we analyze this proposal in more detail and provide predictions for the EIC based on the available determinations of the color-octet matrix elements. We also propose two additional methods that do not require comparison to open heavy-quark pair production., Comment: 10 pages, 9 figures; some small additions to the text, corrections to eqs. 37-38, conclusions unchanged, matches version accepted by Physical Review D
- Published
- 2021
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47. Elektron ışın eritme yöntemi kullanılarak sekizli kafes örgü yapıların mekanik ve geometrik özelliklerinin karşılaştırılması
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Bilçen Mutlu
- Subjects
Materials science ,Octet ,Cathode ray ,Engineering, Multidisciplinary ,Pharmacology (medical) ,Crystal structure ,Mühendislik, Ortak Disiplinler ,Kafes yapıları,Sekizli örgü kafes yapılar,Ti-6Al-4V,Eklemeli imalat ,Molecular physics ,Lattice structures,Octet truss,Ti-6Al-4V,Additive manufacturing - Abstract
Additive manufacturing methods allow to produce complex geometries such as lattice structures. Aim of this study is to identify octet truss lattice structure’s mechanical capabilities. Firstly, octet truss structure designed and used to fill specimens. Specimens 1, 2 and 4 with wall and lattice structure, specimen 3 only with lattice structure and also a filled specimen are modelled. Modelled tensile specimens are additively manufactured from Ti-6Al-4V with Electron Beam Melting method. A comparison between specimens having same structural design (1, 2 and 4) has been made to gain insight about consistency of EBM method. Tensile experiments have been made with all of the specimens and tensile strength difference that can be considered significant determined among specimen 1, 2&4. Specimen 3 resulted not to be a practical approach as it showed poor tensile strength values. Lastly, tensile stress results of filled specimen are shared and compared with the other types of specimens. These results are providing a good sight for assessment of both octet truss structure and EBM manufacturing technology., Katmanlı üretim yöntemleri, kafes yapıları gibi karmaşık geometrilerin üretimine izin veren yeni bir teknolojidir. Bu çalışmanın amacı sekizli kafes yapısının mekanik özelliklerini belirlemektir. İlk olarak, kafes yapısı oluşturulmamış ve tamamen dolu bir numune kullanılmıştır. 1,2 ve 4 numaralı numuneler duvar kalınlıkla kafes yapıdan modellenmiş, yalnızca 3 numaralı numune duvar kalınlıklı sekizli kafes yapısından oluşturulmuştur. Modellenen çekme numuneleri, Elektron Işını Eritme yöntemi ile Ti-6Al-4V'den malzeme kullanılarak üretilmiştir. EBM yönteminin tutarlılığı hakkında fikir edinmek için aynı yapısal tasarıma (1, 2 ve 4) sahip numuneler arasında bir karşılaştırma yapılmıştır. 1, 2 ve 4 numaralı numuneler arasında önemli sayılabilecek gerilme mukavemeti farkı belirlenmiştir. Numune 3, zayıf gerilme mukavemeti değerleri göstermiştir. Son olarak, doldurulmuş bir numunenin çekme gerilmesi sonuçları paylaşılmış ve diğer numunelerin sonuçlarıyla karşılaştırılmıştır. Bu sonuçlar hem sekizli kafes yapısı hem de EBM üretim teknolojisinin değerlendirilmesi açısından önemlidir.
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- 2021
48. Study of the $Y(4660)$ from a light-quark perspective
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Yun-Hua Chen
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Quark ,Physics ,Particle physics ,Octet ,High Energy Physics::Lattice ,Spectrum (functional analysis) ,High Energy Physics::Phenomenology ,FOS: Physical sciences ,State (functional analysis) ,Helicity ,Spectral line ,High Energy Physics - Experiment ,High Energy Physics - Experiment (hep-ex) ,High Energy Physics - Phenomenology ,High Energy Physics - Phenomenology (hep-ph) ,Invariant mass ,High Energy Physics::Experiment ,Singlet state - Abstract
In this paper, we try to reveal the structure of the $Y(4660)$ from the light-quark perspective. We study the dipion invariant mass spectrum and the helicity angular distributions of the $e^+ e^- \to Y(4660) \to \psi(2S) \pi^+\pi^-$ process. In particular, we consider the effects of different light-quark SU(3) eigenstates inside the $Y(4660)$. The strong pion-pion final-state interactions as well as the $K\bar{K}$ coupled channel in the $S$-wave are taken into account model independently by using dispersion theory. We find that the light-quark SU(3) octet state plays a significant role in this transition, implying that the $Y(4660)$ contains a large light-quark component and thus might not be a pure conventional charmonium state. In the fit scheme considering both the SU(3) singlet and SU(3) octet states, two solutions are found, and both solutions reproduce the $\pi\pi$ invariant mass spectra well. New measurement data with higher statistics in the future will be helpful to better distinguish these two solutions., Comment: 16 pages, 5 figures, discussion of the SU(3) flavor breaking effect added, calculations of the $Z$-exchange mechanism and the triangle diagrams added, version accepted for publication in PRD. arXiv admin note: substantial text overlap with arXiv:1902.10957
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- 2021
49. Comparison of 5 monoclonal antibodies for immunopurification of human butyrylcholinesterase on Dynabeads: KD values, binding pairs, and amino acid sequences.
- Author
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Peng, Hong, Brimijoin, Stephen, Hrabovska, Anna, Targosova, Katarina, Krejci, Eric, Blake, Thomas A., Johnson, Rudolph C., Masson, Patrick, and Lockridge, Oksana
- Subjects
- *
MONOCLONAL antibodies , *BUTYRYLCHOLINESTERASE , *IMMUNOGLOBULINS , *CHOLINESTERASES , *PEPTIDES - Abstract
Human butyrylcholinesterase (HuBChE) is a stoichiometric bioscavenger of nerve agents and organophosphorus pesticides. Mass spectrometry methods detect stable nerve agent adducts on the active site serine of HuBChE. The first step in sample preparation is immunopurification of HuBChE from plasma. Our goal was to identify monoclonal antibodies that could be used to immunopurify HuBChE on Dynabeads Protein G. Mouse anti-HuBChE monoclonal antibodies were obtained in the form of ascites fluid, dead hybridoma cells stored frozen at −80 °C for 30 years, or recently frozen hybridoma cells. RNA from 4 hybridoma cell lines was amplified by PCR for determination of their nucleotide and amino acid sequences. Full-length light and heavy chains were expressed, and the antibodies purified from culture medium. A fifth monoclonal was purchased. The 5 monoclonal antibodies were compared for ability to capture HuBChE from human plasma on Dynabeads Protein G. In addition, they were evaluated for binding affinity by Biacore and ELISA. Epitope mapping by pairing analysis was performed on the Octet Red96 instrument. The 5 monoclonal antibodies, B2 12-1, B2 18-5, 3E8, mAb2, and 11D8, had similar K D values of 10 −9 M for HuBChE. Monoclonal B2 18-5 outperformed the others in the Dynabeads Protein G assay where it captured 97% of the HuBChE in 0.5 ml plasma. Pairing analysis showed that 3E8 and B2 12-1 share the same epitope, 11D8 and B2 18-5 share the same epitope, but mAb2 and B2 12-1 or mAb2 and 3E8 bind to different epitopes on HuBChE. B2 18-5 was selected for establishment of a stable CHO cell line for production of mouse anti-HuBChE monoclonal. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
50. Low-energy scattering and effective interactions of two baryons at mπ∼450 MeV from lattice quantum chromodynamics
- Author
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William Detmold, Phiala E. Shanahan, Emmanuel Chang, Assumpta Parreño, Kostas Orginos, Michael L. Wagman, Zohreh Davoudi, Marc Illa, Martin J. Savage, David Murphy, Frank Winter, and Silas R. Beane
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Quantum chromodynamics ,Quark ,Physics ,Particle physics ,Octet ,010308 nuclear & particles physics ,Nuclear Theory ,Lattice QCD ,Strangeness ,01 natural sciences ,Baryon ,Pion ,0103 physical sciences ,Bound state ,010306 general physics - Abstract
The interactions between two octet baryons are studied at low energies using lattice QCD (LQCD) with larger-than-physical quark masses corresponding to a pion mass of $m_{\pi}\sim 450$ MeV and a kaon mass of $m_{K}\sim 596$ MeV. The two-baryon systems that are analyzed range from strangeness $S=0$ to $S=-4$ and include the spin-singlet and triplet $NN$, $\Sigma N$ ($I=3/2$), and $\Xi\Xi$ states, the spin-singlet $\Sigma\Sigma$ ($I=2$) and $\Xi\Sigma$ ($I=3/2$) states, and the spin-triplet $\Xi N$ ($I=0$) state. The $s$-wave scattering phase shifts, low-energy scattering parameters, and binding energies when applicable, are extracted using L\"uscher's formalism. While the results are consistent with most of the systems being bound at this pion mass, the interactions in the spin-triplet $\Sigma N$ and $\Xi\Xi$ channels are found to be repulsive and do not support bound states. Using results from previous studies at a larger pion mass, an extrapolation of the binding energies to the physical point is performed and is compared with experimental values and phenomenological predictions. The low-energy coefficients in pionless EFT relevant for two-baryon interactions, including those responsible for $SU(3)$ flavor-symmetry breaking, are constrained. The $SU(3)$ symmetry is observed to hold approximately at the chosen values of the quark masses, as well as the $SU(6)$ spin-flavor symmetry, predicted at large $N_c$. A remnant of an accidental $SU(16)$ symmetry found previously at a larger pion mass is further observed. The $SU(6)$-symmetric EFT constrained by these LQCD calculations is used to make predictions for two-baryon systems for which the low-energy scattering parameters could not be determined with LQCD directly in this study, and to constrain the coefficients of all leading $SU(3)$ flavor-symmetric interactions, demonstrating the predictive power of two-baryon EFTs matched to LQCD.
- Published
- 2021
- Full Text
- View/download PDF
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