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18 results on '"Ocejo-Vinyals, Gonzalo"'

2. The age again in the eye of the COVID-19 storm: evidence-based decision making

Author

Martín, María C., Jurado, Aurora, Abad-Molina, Cristina, Orduña, Antonio, Yarce, Oscar, Navas, Ana M., Cunill, Vanesa, Escobar, Danilo, Boix, Francisco, Burillo-Sanz, Sergio, Vegas-Sánchez, María C., Jiménez-de las Pozas, Yesenia, Melero, Josefa, Aguilar, Marta, Sobieschi, Oana Irina, López-Hoyos, Marcos, Ocejo-Vinyals, Gonzalo, San Segundo, David, Almeida, Delia, Medina, Silvia, Fernández, Luis, Vergara, Esther, Quirant, Bibiana, Martínez-Cáceres, Eva, Boiges, Marc, Alonso, Marta, Esparcia-Pinedo, Laura, López-Sanz, Celia, Muñoz-Vico, Javier, López-Palmero, Serafín, Trujillo, Antonio, Álvarez, Paula, Prada, Álvaro, Monzón, David, Ontañón, Jesús, Marco, Francisco M., Mora, Sergio, Rojo, Ricardo, González-Martínez, Gema, Martínez-Saavedra, María T., Gil-Herrera, Juana, Cantenys-Molina, Sergi, Hernández, Manuel, Perurena-Prieto, Janire, Rodríguez-Bayona, Beatriz, Martínez, Alba, Ocaña, Esther, and Molina, Juan

Published
2021
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3. COVID-19: age, Interleukin-6, C-reactive protein, and lymphocytes as key clues from a multicentre retrospective study

Author

Jurado, Aurora, Martín, María C., Abad-Molina, Cristina, Orduña, Antonio, Martínez, Alba, Ocaña, Esther, Yarce, Oscar, Navas, Ana M., Trujillo, Antonio, Fernández, Luis, Vergara, Esther, Rodríguez, Beatriz, Quirant, Bibiana, Martínez-Cáceres, Eva, Hernández, Manuel, Perurena-Prieto, Janire, Gil, Juana, Cantenys, Sergi, González-Martínez, Gema, Martínez-Saavedra, María T., Rojo, Ricardo, Marco, Francisco M., Mora, Sergio, Ontañón, Jesús, López-Hoyos, Marcos, Ocejo-Vinyals, Gonzalo, Melero, Josefa, Aguilar, Marta, Almeida, Delia, Medina, Silvia, Vegas, María C., Jiménez, Yesenia, Prada, Álvaro, Monzón, David, Boix, Francisco, Cunill, Vanesa, and Molina, Juan

Published
2020
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4. Clinical and immunological study of Tofacitinib and Baricitinib in refractory Blau syndrome: case report and literature review

Author

Álvarez-Reguera, Carmen, primary, Prieto-Peña, Diana, additional, Herrero-Morant, Alba, additional, Sánchez-Bilbao, Lara, additional, Martín-Varillas, José Luis, additional, González-López, Elena, additional, Gutiérrez-Larrañaga, María, additional, San Segundo, David, additional, Demetrio-Pablo, Rosalía, additional, Ocejo-Vinyals, Gonzalo, additional, González-Gay, Miguel A., additional, and Blanco, Ricardo, additional

Published
2022
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5. Brief Report: Association of HLA–DRB1*01 With IgA Vasculitis (Henoch-Schönlein)

Author

López-Mejías, Raquel, Genre, Fernanda, Pérez, Belén Sevilla, Castañeda, Santos, Ortego-Centeno, Norberto, Llorca, Javier, Ubilla, Begoña, Remuzgo-Martínez, Sara, Mijares, Verónica, Pina, Trinitario, Calvo-Río, Vanesa, Márquez, Ana, Sala-Icardo, Luis, Miranda-Filloy, José A., Conde-Jaldón, Marta, Ortiz-Fernández, Lourdes, Rubio, Esteban, Luque, Manuel León, Blanco-Madrigal, Juan M., Galíndez-Aguirregoikoa, Eva, González-Vela, Carmen M., Ocejo-Vinyals, Gonzalo J., Escribano, Francisca González, Martín, Javier, Blanco, Ricardo, and González-Gay, Miguel A.

Published
2015
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6. COVID-19 in Spain: age, Interleukin-6, C Reactive Protein and lymphocytes as key clues from a multicentre retrospective study

Author

Jurado, Aurora, Martin Sr., M Carmen, Abad-Molina, Cristina, Orduna, Antonio, Martinez, Alba, Ocana, Esther, Yarce, Oscar, Navas, Ana M, Trujillo, Antonio, Fernandez-Pereira, Luis, Vergara, Esther, Rodriguez, Beatriz, Quirant, Bibiana, Martinez, Eva, Hernandez, Manuel, Perurena, Janire, Gil, Juana, Cantenys, Sergi, Gonzalez-Martinez, Gema, Martinez-Saavedra, Maria Teresa, Rojo, Ricardo, Marco, Francisco M, Mora, Sergio, Ontanon, Jesus, Lopez-Hoyos, Marcos, Ocejo-Vinyals, Gonzalo, Melero, Josefa, Aguilar, Marta, Almeida, Delia, Medina, Silvia, Vegas, Maria Carmen, Jimenez, Yesenia, Prada, Alvaro, Monzon, David, Boix, Francisco, Cunil, Vanesa, and Molina, Juan

Abstract

SARS-CoV-2 infection has widely spread to the hugest public health challenge to date, COVID-19 pandemic. Different fatality rates among countries are probably due to unstandardized records being carried out by local health authorities. Spanish case-fatality rate is 11.86%, far higher to those reported in Asia or by other European countries. A multicenter retrospective study of demographic, clinical, laboratory and immunological features of 574 Spanish COVID-19 inpatients (59.4% males) and their outcomes was performed. 27.7% cases presented a mild curse, 42% a moderate one and 30.3%, severe. Ages ranged from 18 to 98 (average 63.2). Interleukin 6 was higher as increasing severity. On the other hand, CD8 lymphocyte count was significantly lower as severity grew and subpopulations CD4, CD8, CD19 and NK showed concordant lowering trends. Severity-related natural killer percent descents were evidenced just within aged cases. A significant severity-related decrease of CD4 lymphocytes was found in males. The use of renin-angiotensin system blockers was associated with moderate or mild disease courses. Clinical course of the disease is more severe in this study than in previous literature cohorts. Age and age-related comorbidities, such as dyslipidemia, hypertension or diabetes, were also higher. Immunosenescence might be therefore a suitable explanation for immune system effectors severity-related hampering. Adaptive immunity would go exhausted and a huge ineffective and almost deleterious innate response would account for COVID-19 severity. Hypertensive patients treated with renin-angiotensin system blockers developed milder forms of the disease.

Published
2020
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7. The Age Again in The Eye of The Covid-19 Storm: Evidence-Based Decision Making.

Author

Martín, M. Carmen, primary, Jurado, Aurora, additional, Abad-Molina, Cristina, additional, Orduña, Antonio, additional, Yarce, Oscar, additional, Navas, Ana M., additional, Cunill, Vanesa, additional, Escobar, Danilo, additional, Boix, Francisco, additional, Burillo-Sanz, Sergio, additional, Vegas-Sánchez, María C., additional, Pozas, Yesenia Jiménez-de las, additional, Melero, Josefa, additional, Aguilar, Marta, additional, Sobieschi, Oana Irina, additional, López-Hoyos, Marcos, additional, Ocejo-Vinyals, Gonzalo, additional, Segundo, David San, additional, Almeida, Delia, additional, Medina, Silvia, additional, Fernández-Pereira, Luis, additional, Vergara, Esther, additional, Quirant, Bibiana, additional, Martínez-Cáceres, Eva, additional, Boigues, Marc, additional, Alonso, Marta, additional, Esparcia-Pinedo, Laura, additional, López-Sanz, Celia, additional, Muñoz-Vico, Javier, additional, López-Palmero, Serafín, additional, Trujillo, Antonio, additional, Álvarez, Paula, additional, Prada, Álvaro, additional, Monzón, David, additional, Ontañón, Jesús, additional, Marco, Francisco M., additional, Mora, Sergio, additional, Rojo, Ricardo, additional, González-Martínez, Gema, additional, Martínez-Saavedra, María T., additional, Gil-Herrera, Juana, additional, Cantenys-Molina, Sergi, additional, Hernández, Manuel, additional, Perurena-Prieto, Janire, additional, Rodríguez-Bayona, Beatriz, additional, Martínez, Alba, additional, Ocaña, Esther, additional, and Molina, Juan, additional

Published
2021
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8. Serum CGRP, VIP, and PACAP Usefulness in Migraine: A Case-Control Study in Chronic Migraine Patients in Real Clinical Practice.

Author

Pereda, Sara Pérez, primary, Toriello-Suárez, María, additional, Ocejo-Vinyals, Gonzalo, additional, Guiral-Foz, Sandra, additional, Castillo-Obeso, Jesús, additional, Montes-Gómez, Silvia, additional, Martínez-Nieto, Rosa M, additional, Iglesias, Fernando, additional, González-Quintanilla, Vicente, additional, and Oterino, Agustin, additional

Published
2020
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9. COVID-19: age, Interleukin-6, C-Reactive Protein and lymphocytes as key clues from a multicentre retrospective study in Spain

Author

Jurado, Aurora, primary, Martín, María C., additional, Abad-Molina, Cristina, additional, Orduña, Antonio, additional, Martínez, Alba, additional, Ocaña, Esther, additional, Yarce, Oscar, additional, Navas, Ana M., additional, Trujillo, Antonio, additional, Fernández, Luis, additional, Vergara, Esther, additional, Rodríguez, Beatriz, additional, Quirant, Bibiana, additional, Martínez-Cáceres, Eva, additional, Hernández, Manuel, additional, Perurena-Prieto, Janire, additional, Gil, Juana, additional, Cantenys, Sergi, additional, González-Martínez, Gema, additional, Martínez-Saavedra, María T., additional, Rojo, Ricardo, additional, Marco, Francisco M., additional, Mora, Sergio, additional, Ontañón, Jesús, additional, López-Hoyos, Marcos, additional, Ocejo-Vinyals, Gonzalo, additional, Melero, Josefa, additional, Aguilar, Marta, additional, Almeida, Delia, additional, Medina, Silvia, additional, Vegas, María C., additional, Jiménez, Yesenia, additional, Prada, Álvaro, additional, Monzón, David, additional, Boix, Francisco, additional, Cunill, Vanesa, additional, and Molina, Juan, additional

Published
2020
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10. Primary and Secondary Immunodeficiency Diseases in Oncohaematology: Warning Signs, Diagnosis, and Management

Author

Sanchez-Ramon, Silvia, Bermudez, Arancha, Ignacio Gonzalez-Granado, Luis, Rodriguez-Gallego, Carlos, Sastre, Ana, Soler-Palacin, Pere, Alonso, Laura, Allende, Luis, Alsina, Laia, Maria Bielsa, Ana, Calleja-Antolin, Sara, Camara, Carmen, Carbone, Javier, Carreras, Carmen, De Andres Martin, Ana, Deya, Angela, Diaz de Heredia, Cristina, Dieli-Crimi, Romina, Luis Diez, Jose, Dominguez-Pinilla, Nerea, Fernandez-Pereira, Luis, Ma Garcia, Jose, Gil-Herrera, Juana, Gutierrez, Antonio, Jarque, Isidro, Juan, Manel, Lendinez, Francisco, Llobet, Pilar, Lopez, Monica, Lopez de la Guia, Ana, Lopez-Hoyos, Marcos, Martin-Nalda, Andrea, Martinez, Monica, Melero, Josefa, Mendez-Echevarria, Ana, Moral, Pedro, Neth, Olaf, Nunez, Maria, Ocejo-Vinyals, Gonzalo, Ochoa-Grullon, Juliana, Olbrich, Peter, Ona, Raquel, Perez-Encinas, Manuel, Pons, Jaime, Rodriguez, Carmen, Sanchez, Berta, Luis Santos-Perez, Juan, Elena Seoane, Ma, Vlagea, Alexandru, ID Signal Oncohaematology Grp, Institut Català de la Salut, [Sánchez-Ramón S] Hospital Clínico San Carlos, Madrid, Spain. [Bermúdez A] Hospital Universitario Marqués de Valdecilla, Santander, Spain. [González-Granado LI] Hospital Universitario 12 Octubre, Madrid, Spain. [Rodríguez-Gallego C] Hospital Universitario de Gran Canaria Dr. Negrín, Las Palmas de Gran Canaria, Canary Islands, Spain. [Sastre A] Hospital Universitario La Paz, Madrid, Spain. [Soler-Palacín P] Hospital Universitari Vall d'Hebron, Barcelona, Spain., and Vall d'Hebron Barcelona Hospital Campus

Subjects
0301 basic medicine, inmunoglobulinas, calidad, acceso y evaluación de la atención sanitaria::calidad de la atención sanitaria::factores epidemiológicos::comorbilidad [ATENCIÓN DE SALUD], humanos, immunoglobulins/deficiency, 0302 clinical medicine, Clinical history, Other subheadings::/diagnosis [Other subheadings], Immunology and Allergy, Medicine, Child, Paediatric patients, Original Research, Hematology, autoimmunity, Immunoglobulins, Intravenous, adulto, enfermedades del sistema inmune::síndromes de inmunodeficiencia [ENFERMEDADES], Warning signs, Síndromes de deficiència immunitària - Diagnòstic, Hematologic Neoplasms, Immune System Diseases::Immunologic Deficiency Syndromes [DISEASES], antibodies/deficiency, lcsh:Immunologic diseases. Allergy, Adult, medicine.medical_specialty, Sang - Càncer, síndromes de inmunodeficiencia, Primary Immunodeficiency Diseases, Immunology, Otros calificadores::/diagnóstico [Otros calificadores], Lymphoproliferative disorders, Immunoglobulins, Primary care, Secondary immunodeficiency, 03 medical and health sciences, Comorbiditat, immunoglobulins/administration and dosage, Internal medicine, Humans, Health Care Quality, Access, and Evaluation::Quality of Health Care::Epidemiologic Factors::Comorbidity [HEALTH CARE], neoplasias::neoplasias por localización::neoplasias hematológicas [ENFERMEDADES], Intensive care medicine, Cytopenia, business.industry, Immunologic Deficiency Syndromes, Neoplasms::Neoplasms by Site::Hematologic Neoplasms [DISEASES], medicine.disease, neoplasias hematológicas, 030104 developmental biology, lcsh:RC581-607, business, 030215 immunology
Abstract

Background: Immunodeficiencies (ID), in particular primary immunodeficiencies (PID), are often associated with haematological manifestations, such as peripheral cytopenias or lymphoproliferative syndromes. Early diagnosis and management have significant prognostic implications. Secondary immunodeficiencies (SID) may also be induced by oncohaematological diseases and their treatments. Haematologists and oncologists must therefore be aware of the association between blood disorders and cancer and ID, and be prepared to offer their patients appropriate treatment without delay. Our aim was to define the warning signs of primary and secondary IDs in paediatric and adult patients with oncohaematological manifestations. Methods: A multidisciplinary group of six experts (2 haematologists, 2 immunologists, and 2 paediatricians specializing in ID) conducted a literature review and prepared a document based on agreements reached an in-person meeting. An external group of 44 IDs specialists from all over Spain assessed the document and were consulted regarding their level of agreement. Results: This document identifies the haematological and extra-haematological diseases that should prompt a suspicion of PIDs in adults and children, in both primary care and haematology and oncology departments. Cytopenia and certain lymphoproliferative disorders are key diagnostic pointers. The diagnosis must be based on a detailed clinical history, physical exploration, complete blood count and standard laboratory tests. The immunological and haematological tests included in the diagnostic process will depend on the care level. Patients who are candidates for immunoglobulin replacement therapy must be carefully selected, and treatment should be offered as soon as possible to avoid the development of complications. Finally, this document recommends procedures for monitoring these patients. Conclusions: This document combines scientific evidence with the opinion of a broad panel of experts, and emphasizes the importance of an early diagnosis and treatment to avoid complications. The resulting document is a useful tool for primary care physicians and specialists who see both adult and paediatric patients with oncohaematological diseases., This article received funding fee from CSL Behring.

Published
2019
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13. Protein tyrosine phosphatase non-receptor 22 and C-Src tyrosine kinase genes are down-regulated in patients with rheumatoid arthritis

Author

Remuzgo-Martínez, Sara, primary, Genre, Fernanda, additional, Castañeda, Santos, additional, Corrales, Alfonso, additional, Moreno-Fresneda, Pablo, additional, Ubilla, Begoña, additional, Mijares, Verónica, additional, Portilla, Virginia, additional, González-Vela, Jesús, additional, Pina, Trinitario, additional, Ocejo-Vinyals, Gonzalo, additional, Irure-Ventura, Juan, additional, Blanco, Ricardo, additional, Martín, Javier, additional, Llorca, Javier, additional, López-Mejías, Raquel, additional, and González-Gay, Miguel A., additional

Published
2017
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18. Pulmonary inflammatory pseudotumor with HHV-8.

Author

Ding Y, Saylors RL, Brown H, Parham DM, Gómez-Román JJ, Sánchez-Velasco P, Ocejo-Vinyals G, Leyva-Cobián F, and Val-Bernal JF

Subjects
Child, Female, Humans, Orbital Diseases etiology, Herpesviridae Infections complications, Herpesvirus 8, Human, Plasma Cell Granuloma, Pulmonary etiology
Published
2002
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