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1. MANUAL DA INICIAÇÃO CIENTÍFICA PARA ESTUDANTES DE MEDICINA

Author

ATARI, N. S. B., primary, Solanho, Sulzbach Gabriela, additional, SCREMIN, L. G., additional, BELTRÃO, J. R., additional, YAMASHITA, E. M., additional, NOVAIS, P. M., additional, OBLADEN, M. E., additional, ANA, M. G. S., additional, KLÜBER, I., additional, LATTMANN, L. M., additional, CARLOTTO, G., additional, BOSCO, G. B. D., additional, BARBOSA, G. F., additional, CAVASSIM, G. L., additional, NIZER, B. G. C., additional, FREITAS, G. M., additional, FREITAS, Á. C., additional, LESKO, V., additional, MECABO, A., additional, VILVERT, A., additional, MAIS, S., additional, MOTA, J., additional, PACHNICKI, J. P. A., additional, NISIHARA, R. M., additional, ANDRADE, F. A., additional, AMBROSIO, A. R., additional, and Giovanini, Allan F, additional

Published
2021
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5. Transport

Author

Obladen, M., Obladen, Michael, editor, and Maier, Rolf F., editor

Published
2006
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18. Künstliche Beatmung

Author

Obladen, M., Obladen, Michael, Bein, Georg, editor, Maier, Rolf F., editor, and Waldschmidt, Jürgen, editor

Published
2002
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19. Ernährung

Author

Obladen, M., Obladen, Michael, Bein, Georg, editor, Maier, Rolf F., editor, and Waldschmidt, Jürgen, editor

Published
2002
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23. Transport

Author

Obladen, M., Obladen, Michael, Bein, Georg, editor, Maier, Rolf F., editor, and Waldschmidt, Jürgen, editor

Published
2002
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29. Infektionen

Author

Obladen, M., Obladen, Michael, Bein, Georg, editor, Maier, Rolf F., editor, and Waldschmidt, Jürgen, editor

Published
2002
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33. Characterization of the vitamin A transport in preterm infants after repeated high-dose vitamin A injections

Author

Longardt, A.C., Schmiedchen, B., Raila, J., Schweigert, F.J., Obladen, M., Buhrer, C., and Loui, A.

Subjects
Biological transport -- Research, Vitamin A -- Health aspects -- Physiological aspects, Pediatric research, Infants (Premature) -- Physiological aspects -- Food and nutrition, Food/cooking/nutrition, Health
Abstract

BACKGROUND/OBJECTIVES: Preterm infants have low vitamin A stores at birth, and parenteral administration of high-dose vitamin A reduces pulmonary morbidity. The aim was to characterize vitamin A transport and status. SUBJECTS/METHODS: Prospective study of 69 preterm infants (median birth weight 995 g, gestational age 28 weeks), in which 51 received 5000 IU vitamin A three times per week intramuscular (i.m.) for 4 weeks and 18 infants without i.m. vitamin A served as controls. Serum retinol, retinyl palmitate, total retinol-binding protein 4 (RBP4), retinol-unbound RBP4 (apo-RBP4) and transthyretin concentrations were determined at days 3 (D3) and 28 (D28) of life. RESULTS: D3 retinol concentrations were low for the entire group (382 (285/531) nmol/l; median/interquartile range) and unrelated to gestational age. D28 retinol was unchanged in controls (382 (280/471) nmol/l), but increased in the vitamin A group (596 (480/825) nmol/l; P < 0.001). A similar pattern was observed for RBP4. The calculated retinol-to-RBP4 ratio rose in vitamin A infants (D3: 0.81 (0.57/0.94), D28: 0.98 (0.77/1.26); P < 0.01) but not in controls. In the vitamin A group, the retinol-to- RBP4 ratio was > 1 in 15% of all infants on D3 and in 45% of infants on D28, but was ≤ 1 in all, but one, controls on D28. CONCLUSIONS: In preterm infants receiving a 4-week course of high-dose i.m. vitamin A, serum retinol concentrations increased by 55%, with molar concentrations of retinol exceeding those of RBP4 in 45% of the infants suggesting transport mechanisms other than RBP4. European Journal of Clinical Nutrition (2014) 68, 1300-1304; doi: 10.1038/ejcn.2014.202; published online 15 October 2014, INTRODUCTION An adequate vitamin A supply is essential for normal fetal and postnatal development. During pregnancy, retinol reaches the fetus via the placenta, whereas after birth it is ingested as [...]

Published
2014
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34. Künstliche Beatmung

Author

Obladen, M., Obladen, Michael, Bein, Georg, editor, Kattner, Evelyn, editor, and Waldschmidt, Jürgen, editor

Published
1995
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39. Transport

Author

Obladen, M., Obladen, Michael, Bein, Georg, editor, Kattner, Evelyn, editor, and Waldschmidt, Jürgen, editor

Published
1995
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45. Infektionen

Author

Obladen, M., Obladen, Michael, Bein, Georg, editor, Kattner, Evelyn, editor, and Waldschmidt, Jürgen, editor

Published
1995
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48. Audiologie, Varia

Author

Gobsch, H., Tietze, G., Böhnke, F., Koch, A., Kiefer, A., Klein, B., Delb, W., Hauser, R., Probst, R., Richter, B., Plinkert, P. K., Harris, F. P., Hoth, S., Bönnhoff, S., Schultze, J. M., Kühn, A. G., Kau, R. J., Welzl-Müller, K., Stephan, K., Kronthaler, M., Rödel, R., Schuster, B., Raatz, H., Beck, E., Berg, M., Ernst, A., Lenarz, Th., Issing, P. R., Zenner, H. P., Aust, G., Obladen, M., Lohrer, R., Marangos, N., Lehnhardt, E., Lütkenhöner, B., Panter, C., Hoke, M., Moser, L. M., Müller, E., Wetzel, S., Möckel, U., Pilgramm, M., Köchy, H.-P., Ising, H., Gstöttner, W., Steurer, M., Baumgartner, W., Brügel, F. J., Schorn, K., von Wedel, H., von Wedel, U.-Ch., Feldmann, Harald, and Herberhold, Claus

Published
1993
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