381 results on '"Obika S"'
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2. Nucleic acid delivery systems based on poly(galactosyl ureaethyl methacrylate-b-dimethylamino ethyl methacrylate) diblock copolymers
3. Nucleotide Modification and Polymerase Engineering for Creating a Novel Class of Artificial Nucleic Acid Aptamers
4. Recent Advances in Medicinal Chemistry of Antisense Oligonucleotides
5. Improving Platinum Drug Resistance of Ovarian Cancer by 2′,4′-BNA antisense oligonucleotide of Annexin A4: FC 16.06
6. Crystal structure of Ag-mediated base pairs in uncanonical DNA duplex
7. Nucleotide Modification and Polymerase Engineering for Creating a Novel Class of Artificial Nucleic Acid Aptamers
8. Antisense oligonucleotides containing amido-bridged nucleic acid reduce SNCA expression and improve motor function in Parkinson's disease animal models
9. Crystal Structure Analysis of DNA Duplexes containing sulfoamide-bridged nucleic acid (SuNA-NMe)
10. Wavelength-selective light-triggered strand exchange reaction
11. Crystal structure of DNA/RNA duplex obtained in the presence of [Co(NH3)6]Cl3 and SrCl2
12. Crystal structure of DNA/RNA duplex obtained in the presence of Spermine
13. Crystal structure of DNA/RNA duplex containing 2'-4'-BNA-NC
14. C5-azobenzene-functionalized locked nucleic acid uridine: isomerization properties, hybridization ability, and enzymatic stability
15. Long term effect of bridged nucleic acid (BNA)-based antisense targeting pcsk9 on metabolism and inflammation
16. ChemInform Abstract: Novel and Chiral Hantzsch-Type 1,4-Dihydropyridines Having a p- Tolylsulfinyl Group. Synthesis and Biological Activities as Calcium Channel Antagonists.
17. ChemInform Abstract: Studies on Novel and Chiral 1,4-Dihydropyridines. Part 1. Synthesis and Conformational Analysis of Novel NADH Model Compounds, N- Substituted (S)-3-(p-Tolylsulfinyl)-1,4-dihydropyridines.
18. ChemInform Abstract: Effect of the Neighboring Oxygenated Substituent on Asymmetric Reduction with Hantzsch-Type 1,4-Dihydropyridines Having a Chiral Sulfinyl Group.
19. ChemInform Abstract: Stereospecific 4-Hydrogen Transfer in the Asymmetric Reduction Using ( SS)-3-(p-Tolylsulfinyl)-1,4-dihydropyridines, NADH Model Compounds.
20. ChemInform Abstract: Studies on Novel and Chiral 1,4-Dihydropyridines. Part 3. Asymmetric Reduction of Some Ketones with Novel NADH Model Compounds, (SS)-3-(p- Tolylsulfinyl)-1,4-dihydropyridines.
21. ChemInform Abstract: Synthesis of 2′-O,4′-C-Methyleneuridine and -cytidine. Novel Bicyclic Nucleosides Having a Fixed C3′-endo Sugar Puckering.
22. Promotion of triplex formation by 3'-amino-2'-O,4'-C-methylene bridged nucleic acid modification
23. Synthesis and properties of a novel artificial nucleoside that acts as a redox switch
24. Development of light-responsive BNA toward the spatiotemporal control of gene expression
25. Synthesis and properties of a novel 2',4'-BNA bearing a urea bridged structure
26. Promotion of Triplex Formation by 2'-O,4'-C-Aminomethylene Bridged Nucleic Acid (2',4'-BNANC) Modification
27. Biologically active 2-5A analogs containing 3'-O,4'-C-propylene adenosine as potent RNase L agonists
28. Design and Chemical Synthesis of a 2',4'-BNA Probe for 7,8-Dihydro-8-oxoguanine-containing Double Stranded DNA
29. Antisense activity of 2',4'-BNA targeted to PPAR gamma in THP-1 and HCT116 cells
30. Polymerisation of a DNA strand using oligo-DNA template with modified bases, sugars and phosphates
31. Inhibition of bcl-xLexpression by antisense oligonucleotides containing various bridged nucleic acids (BNAs)
32. Synthesis and evaluation of a novel 2',5'-bridged nucleic acid with sugar conformation fixed to S-type by N-Olinkage
33. Synthesis and properties of a 2'-deoxy analogue of trans-3',4'-BNA with an S-type sugar conformation
34. Synthesis and chemical properties of a novel 2',4'-bridged nucleic acid analogue with a seven-membered cyclic carbamate structure
35. Synthesis of 3-Benzylideneoxindoles
36. A novel nucleic acid analogue, 3'-amino-2'-deoxy-3',4'-BNA, with an N3'->P5' phosphoramidate linkage and an S-type conformation
37. trans-3',4'-BNAs, novel nucleic acid analogues with an S-type conformation: Synthesis and incorporation into oligonucleotides
38. Synthesis and properties of 5'-amino-2',4'-BNA modified oligonucleotides with P3'->N5' phosphoramidate linkages
39. Synthesis and properties of oligonucleotides containing novel 2',4'-BNA analogues (2',4'-BNACOC)
40. Triplex formation involving 2',4'-BNA with isoquinolone base analogue: Efficient and selective recognition of C:G interruption
41. Binding of threading intercalator to nucleic acids: Thermodynamic analyses
42. Triplex formation involving 2',4'-BNA with 2-pyridone base analogue: Efficient and selective recognition of C:G interruption
43. 2', 4'-BNA bearing unnatural nucleobases: Toward the expansion of the target sequence of double-stranded DNA in triplex formation
44. Inhibition of ICAM-I gene expression by antisense 2',4'-BNA oligonucleotides
45. Promotion of triplex formation by a fixed N-form sugar puckering: Thermodynamic and kinetic studies
46. Synthesis and triplex forming ability of conformationally locked oligonucleotides containing unnatural nucleobases: Efficient recognition of a C {middle dot} G interruption
47. Gene Transfer Mediated by YKS-220 Cationic Particles: Convenient and Efficient Gene Delivery Reagent
48. ChemInform Abstract: Stability and Structural Features of the Duplexes Containing Nucleoside Analogues with a Fixed N‐Type Conformation, 2′‐O,4′‐C‐Methyleneribonucleosides.
49. ChemInform Abstract: Synthesis and Conformation of 3′‐O,4′‐C‐Methyleneribonucleosides, Novel Bicyclic Nucleoside Analogues for 2′,5′‐Linked Oligonucleotide Modification.
50. ChemInform Abstract: A Symmetrical and Biodegradable Cationic Lipid. Synthesis and Application for Efficient Gene Transfection.
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