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Ceramic restorations on zirconia framework can be used in different areas of the dental arch, integrating perfectly and can be indicated, concomitantly, in some coronal conditions such as dyschromia, moderate dental abrasions, dystrophies, incipient carious processes, dental dwarfism, dysplasia, dental fractures in the incisal third of the dental units and other malpositions, providing patients with superior results through good marginal adaptation and restoration of interdental relationships. CAD/CAM systems are now widely used in dentistry to make dental restorations. The introduction of these systems in dentistry has made it possible to meet the expectations of patients, who, with the help of chair-side systems, can benefit from high quality and precise prosthetic restorations in a single treatment session. The aim of this study is to individualize the correlation between the clinical and technological stages, the therapeutic solutions being anchored in the non-metallic register, the treatment decision being made according to the particularity of the clinical case, in order to achieve the final clinical success through the aesthetic requirements.

The oral cavity represents an area access zone from the external environment to the internal areas of the body and saliva is at the interface between microbial ecosystems and oral immune cells. Any imbalance of saliva physiology has an impact on oral and systemic health. Elevated inflammatory cytokines in saliva, for example, activates dysbiosis (disease) of periodontal tissues, feeding forward tissue inflammation, leading to oral tissue loss. Host–microbiome interactions complex modulate pathological transitions including gingivitis, periodontal diseases, and oral cancer. However, mechanisms involving these interactions are poorly understood at the molecular level.

With a great prevalence, diseases of the oral cavity and respective tissues are a highly relevant global health issue. The common oral diseases, such as tooth loss, chewing deficiencies and quality of life impairment, oral and systemic disease interaction are apparent. It is very clear already that systemic diseases and conditions have the ability to create a risk of developing oral diseases for example periodontitis; on the other hand, oral inflammation can have an effect on cardiovascular, metabolic, respiratory or bone health. Moreover, several general diseases are related to a potential risk of complications in dental therapy.

Biomechanical induced dental problems affect a relatively high percent of the adult population. The aim of study was to determine the prevalence of specific lesions for dental wear. Material and method The study was conducted on a group of 300 subjects, selected from the 4th Medical Clinic of CFR Clinic Hospital, for which the criteria of including- excluding was respected. For evaluating the alteration degree, the TWI indicator was used, and for statistical analysis the SPSS17 program for Windows. Results and discussions The study highlights a mean variation of patients with wear lesions quantified according to the TWI indicator (3.096 of all patients present stage 1 affection; a mean of 3.066 with stage 2 affection; 3.01 for stage 3 and 2.8 with stage 4 affection). Conclusions There are correlations between sexes, age groups, general status, wear lesion patterns, associated lesions and their predominance.