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2. Circulating plasma phospholipid fatty acid levels as a biomarker of habitual dietary fat intake: The INTERMAP/INTERLIPID Study

Author

Miyagawa, Naoko, Sekikawa, Akira, Miura, Katsuyuki, Evans, Rhobert W., Okuda, Nagako, Fujiyoshi, Akira, Yoshita, Katsushi, Chan, Queenie, Okami, Yukiko, Kadota, Aya, Willcox, Bradley, Masaki, Kamal, Rodriguez, Beatriz, Sakata, Kiyomi, Nakagawa, Hideaki, Saitoh, Shigeyuki, Okayama, Akira, Kuller, Lewis H., Elliott, Paul, Stamler, Jeremiah, and Ueshima, Hirotsugu

Published
2023
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4. Na and K Intake from Lunches Served in a Japanese Company Cafeteria and the Estimated Improvement in the Dietary Na/K Ratio Using Low-Na/K Seasonings and Dairy to Prevent Hypertension

Author

Okuda, Nagako, primary, Higashiyama, Aya, additional, Tanno, Kozo, additional, Yonekura, Yuki, additional, Miura, Makoto, additional, Kuno, Hiroshi, additional, Nakajima, Toru, additional, Nagahata, Tomomi, additional, Taniguchi, Hirokazu, additional, Kosami, Koki, additional, Kojima, Kyoko, additional, and Okayama, Akira, additional

Published
2024
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5. Association of Pro-Inflammatory Diet with Long-Term Risk of All-Cause and Cardiovascular Disease Mortality: NIPPON DATA80

Author

Ganbaatar, Gantsetseg, primary, Okami, Yukiko, additional, Kadota, Aya, additional, Ganbaatar, Namuun, additional, Yano, Yuichiro, additional, Kondo, Keiko, additional, Harada, Akiko, additional, Okuda, Nagako, additional, Yoshita, Katsushi, additional, Okamura, Tomonori, additional, Okayama, Akira, additional, Ueshima, Hirotsugu, additional, and Miura, Katsuyuki, additional

Published
2024
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9. Relationship between carbohydrate and dietary fibre intake and the risk of cardiovascular disease mortality in Japanese: 24-year follow-up of NIPPON DATA80

Author

Miyazawa, Itsuko, Miura, Katsuyuki, Miyagawa, Naoko, Kondo, Keiko, Kadota, Aya, Okuda, Nagako, and Fujiyoshi, Akira

Subjects
Risk factors, Health aspects, Carbohydrates -- Health aspects, Dietary fiber -- Health aspects, Cardiovascular diseases -- Risk factors, Fiber in human nutrition -- Health aspects
Abstract

Author(s): Itsuko Miyazawa [sup.1] , Katsuyuki Miura [sup.2] [sup.3] , Naoko Miyagawa [sup.2] [sup.4] , Keiko Kondo [sup.2] , Aya Kadota [sup.2] [sup.3] , Nagako Okuda [sup.5] , Akira Fujiyoshi [...], Background/Objectives The association between carbohydrate intake and cardiovascular disease (CVD) risk has been investigated, but whether the quality of carbohydrate is more important than its amount is not known. We examined the associations between intake of dietary fibre (DF), carbohydrate, available carbohydrate, and starch with long-term CVD mortality in a Japanese population. Subjects/Methods We prospectively followed 8925 participants (3916 men and 5009 women) aged 30-79 years without CVD at baseline who participated in the National Nutrition Survey in Japan. Cox proportional hazards models were used to estimate multivariable-adjusted hazard ratios (HRs) and their 95% confidence intervals (CIs) for CVD mortality by quartiles of exposure variables. Results During 24 years of follow-up, 823 CVD deaths were observed. In men, the multivariable-adjusted HR for CVD mortality was lower in the highest quartile of DF intake (HR: 0.64; 95% CI: 0.47-0.87; P.sub.trend = 0.007) compared with the lowest quartile. This association was not significant in women. Multivariable-adjusted HR for total stroke mortality was lower in the highest quartile of DF intake (HR: 0.61; 95% CI: 0.38-0.98; P.sub.trend = 0.046) compared with the lowest quartile in women. Carbohydrate, available carbohydrate, and starch intake were not associated with CVD mortality. Conclusions Higher intake of DF was associated significantly with a lower risk of CVD mortality in men and lower risk of stroke mortality in women. Intake of carbohydrate, available carbohydrate, and starch were not associated with the risk of CVD mortality in men or women.

Published
2020
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11. Re-evaluation of the associations of egg intake with serum total cholesterol and cause-specific and total mortality in Japanese women

Author

Nakamura, Yasuyuki, Okamura, Tomonori, Kita, Yoshikuni, Okuda, Nagako, Kadota, Aya, Miura, Katsuyuki, and Okayama, Akira

Subjects
Prevention, Risk factors, Methods, Health aspects, Mortality -- Analysis -- Prevention -- Japan, Chronic diseases -- Risk factors, Women's health -- Analysis -- Health aspects -- Methods, Eggs (Food) -- Evaluation -- Analysis -- Health aspects, Cholesterol, Heart attack, Cancer, Retirement benefits, Women
Abstract

Author(s): Yasuyuki Nakamura [sup.1] [sup.2] , Tomonori Okamura [sup.3] , Yoshikuni Kita [sup.4] , Nagako Okuda [sup.5] , Aya Kadota [sup.2] [sup.6] , Katsuyuki Miura [sup.2] [sup.6] , Akira Okayama [...], Background/objective Egg intake was associated with serum total cholesterol adjusted for age (aTCH) and total mortality in women, but not in men, using data from NIPPON DATA (ND) 80 which followed up for 14 years. Re-evaluation of these associations in a different cohort is needed. Subject/methods We analyzed the associations of egg intake with aTCH and cause-specific and total mortality using the ND90 data set with a 15-year follow-up. A nutritional examination was done at the baseline in 1990 using the food-frequency method and by weighed food records. We followed 4686 female participants (ages [greater than or equal to]30 years), with no history of stroke or myocardial infarction (mean age 52.8 years) for 15 years. Results The participants were divided into 5 egg intake groups ( Conclusions Egg intake was associated with cancer and total mortality. Reducing egg intake may have some definitive health benefits in women in Japan, at least.

Published
2018
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12. Associations of serum LDL particle concentration with carotid intima-media thickness and coronary artery calcification

Author

Ueshima, Hirotsugu, Miura, Katsuyuki, Horie, Minoru, Nakano, Yasutaka, Yamamoto, Takashi, Ogawa, Emiko, Maegawa, Hiroshi, Miyazawa, Itsuko, Murata, Kiyoshi, Mitsunami, Kenichi, Nozaki, Kazuhiko, Shiino, Akihiko, Araki, Isao, Tsuru, Teruhiko, Toyama, Ikuo, Ogita, Hisakazu, Kurita, Souichi, Maeda, Toshinaga, Miyamatsu, Naomi, Kita, Toru, Kimura, Takeshi, Nishio, Yoshihiko, Nakamura, Yasuyuki, Okamura, Tomonori, Sekikawa, Akira, Barinas-Mitchell, Emma J.M., Edmundowicz, Daniel, Ohkubo, Takayoshi, Hozawa, Atsushi, Okuda, Nagako, Higashiyama, Aya, Nagasawa, Shinya, Kita, Yoshikuni, Murakami, Yoshitaka, Kadota, Aya, Fujiyoshi, Akira, Takashima, Naoyuki, Kadowaki, Takashi, Kadowaki, Sayaka, Abbott, Robert D., Ohno, Seiko, Arima, Hisatomi, Hisamatsu, Takashi, Miyagawa, Naoko, Torii, Sayuki, Saito, Yoshino, Zaid, Maryam, Suzuki, Sentaro, and Ito, Takahiro

Published
2016
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13. Effect of diabetes and prediabetes on the development of disability and mortality among middle‐aged Japanese adults: A 22‐year follow up of <scp>NIPPON DATA90</scp>

Author

HOANG, Phap Tran Ngoc, KADOTA, Aya, YANO, Yuichiro, HARADA, Akiko, HAYAKAWA, Takehito, OKAMOTO, Shohei, MIYAGAWA, Naoko, KONDO, Keiko, OKUDA, Nagako, KITA, Yoshikuni, OKAYAMA, Akira, FUJITA, Yukihiro, MAEGAWA, Hiroshi, MIURA, Katsuyuki, OKAMURA, Tomonori, UESHIMA, Hirotsugu, and NIPPON DATA90 Research Group

Subjects
Adult, Disability, Endocrinology, Diabetes and Metabolism, General Medicine, Middle Aged, Prediabetic State, Cohort Studies, Japan, Risk Factors, Activities of Daily Living, Diabetes Mellitus, Internal Medicine, Humans, Prospective Studies, Mortality, Prediabetes, Follow-Up Studies
Abstract

Aims/introduction:To examine the association between diabetes and prediabetes at baseline, and disability, mortality over a 22-year period among middle-aged Japanese adults., Materials and methods:Participants consisted of 1,788 adults aged 45-64 years at baseline from the cohort study National Integrated Project for Prospective Observation of Non-communicable Disease and its Trends in the Aged 1990 (NIPPON DATA90). Disability, defined as having a decline in activities of daily living (ADL), was assessed by a modified Katz questionnaire at four time points. Disability and death without disability for 22-year follow up were used as outcomes to test the association with a diagnosis of diabetes or prediabetes at baseline, using multinomial logistic regression. Adjusted odds ratios (ORs) were obtained from four models that contained appropriate adjustment factors, such as age, sex, smoking status, drinking status, body mass index and cardiovascular risk factors (hypertension, hypercholesterolemia, triglycerides, low serum high-density lipoprotein), at baseline., Results:In the present study, 334 participants (18.7%) reported at least one disability, and 350 (19.6%) were reported dead without observation of disability during follow up. Adjusting sex and other risk factors, participants with diabetes and prediabetes had a higher risk for disability (OR 1.43, 95% confidence interval [CI] 1.07-1.91 and OR 1.66, 95% CI 1.10-2.50, respectively) and for mortality (OR 1.56, 95% CI 1.16-2.08 and OR 1.77, 95% CI 1.18-2.65, respectively) than individuals with normal glucose tolerance., Conclusions:In middle-aged Japanese adults, individuals with diabetes and prediabetes were more likely to be associated with disability and mortality. Our findings suggest that prediabetes and diabetes in middle-aged adults should be paid more attention, and requires more intervention to prevent disability and mortality in later life.

Published
2022
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16. Socioeconomic and lifestyle factors associated with depressive tendencies in general Japanese men and women: NIPPON DATA2010

Author

Suzuki, Harumitsu, Kadota, Aya, Okuda, Nagako, Hayakawa, Takehito, Nishi, Nobuo, Nakamura, Yasuyuki, Arima, Hisatomi, Miyagawa, Naoko, Satoh, Atsushi, Miyamatsu, Naomi, Yanagita, Masahiko, Yatsuya, Hiroshi, Yamagata, Zentaro, Ohkubo, Takayoshi, Okamura, Tomonori, Ueshima, Hirotsugu, Okayama, Akira, Miura, Katsuyuki, and for the NIPPON DATA2010 Research Group

Published
2019
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18. High long-chain n-3 fatty acid intake attenuates the effect of high resting heart rate on cardiovascular mortality risk: A 24-year follow-up of Japanese general population

Author

Hisamatsu, Takashi, Miura, Katsuyuki, Ohkubo, Takayoshi, Yamamoto, Takashi, Fujiyoshi, Akira, Miyagawa, Naoko, Kadota, Aya, Takashima, Naoyuki, Okuda, Nagako, Yoshita, Katsushi, Kita, Yoshikuni, Murakami, Yoshitaka, Nakamura, Yasuyuki, Okamura, Tomonori, Horie, Minoru, Okayama, Akira, and Ueshima, Hirotsugu

Published
2014
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19. Long-chain n-3 polyunsaturated fatty acids intake and cardiovascular disease mortality risk in Japanese: A 24-year follow-up of NIPPON DATA80

Author

Miyagawa, Naoko, Miura, Katsuyuki, Okuda, Nagako, Kadowaki, Takashi, Takashima, Naoyuki, Nagasawa, Shin-ya, Nakamura, Yasuyuki, Matsumura, Yasuhiro, Hozawa, Atsushi, Fujiyoshi, Akira, Hisamatsu, Takashi, Yoshita, Katsushi, Sekikawa, Akira, Ohkubo, Takayoshi, Abbott, Robert D., Okamura, Tomonori, Okayama, Akira, and Ueshima, Hirotsugu

Published
2014
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20. Relationship of three different types of low-carbohydrate diet to cardiometabolic risk factors in a Japanese population: the INTERMAP/INTERLIPID Study

Author

Nakamura, Yasuyuki, Ueshima, Hirotsugu, Okuda, Nagako, Miura, Katsuyuki, Kita, Yoshikuni, Miyagawa, Naoko, Yoshita, Katsushi, Nakagawa, Hideaki, Sakata, Kiyomi, Saitoh, Shigeyuki, Okamura, Tomonori, Okayama, Akira, Choudhry, Sohel R., Rodriguez, Beatriz, Masaki, Kamal H., Chan, Queenie, Elliott, Paul, and Stamler, Jeremiah

Published
2016
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21. Circulating plasma phospholipid fatty acid levels as a biomarker of habitual dietary fat intake: The INTERMAP/INTERLIPID Study

Author

Miyagawa, Naoko, primary, Sekikawa, Akira, additional, Miura, Katsuyuki, additional, Evans, Rhobert W., additional, Okuda, Nagako, additional, Fujiyoshi, Akira, additional, Yoshita, Katsushi, additional, Chan, Queenie, additional, Okami, Yukiko, additional, Kadota, Aya, additional, Willcox, Bradley, additional, Masaki, Kamal, additional, Rodriguez, Beatriz, additional, Sakata, Kiyomi, additional, Nakagawa, Hideaki, additional, Saitoh, Shigeyuki, additional, Okayama, Akira, additional, Kuller, Lewis H., additional, Elliott, Paul, additional, Stamler, Jeremiah, additional, and Ueshima, Hirotsugu, additional

Published
2022
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22. Body weight and lifestyle changes under the COVID-19 pandemic in Japan: a cross-sectional study from NIPPON DATA2010

Author

Taniguchi, Hirokazu, primary, Okuda, Nagako, additional, Arima, Hisatomi, additional, Satoh, Atsushi, additional, Abe, Makiko, additional, Nishi, Nobuo, additional, Higashiyama, Aya, additional, Suzuki, Harumitsu, additional, Ohkubo, Takayoshi, additional, Kadota, Aya, additional, Miura, Katsuyuki, additional, Ueshima, Hirotsugu, additional, and Okayama, Akira, additional

Published
2022
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28. Relationship Between Non-fasting Triglycerides and Cardiovascular Disease Mortality in a 20-year Follow-up Study of a Japanese General Population: NIPPON DATA90

Author

Hirata, Aya, primary, Okamura, Tomonori, additional, Hirata, Takumi, additional, Sugiyama, Daisuke, additional, Ohkubo, Takayoshi, additional, Okuda, Nagako, additional, Kita, Yoshikuni, additional, Hayakawa, Takehito, additional, Kadota, Aya, additional, Kondo, Keiko, additional, Miura, Katsuyuki, additional, Okayama, Akira, additional, and Ueshima, Hirotsugu, additional

Published
2022
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31. Marital status, household size, and lifestyle changes during the first COVID-19 pandemic: NIPPON DATA2010.

Author

Abe, Makiko, Arima, Hisatomi, Satoh, Atsushi, Okuda, Nagako, Taniguchi, Hirokazu, Nishi, Nobuo, Higashiyama, Aya, Suzuki, Harumitsu, Kadota, Aya, Ohkubo, Takayoshi, Ueshima, Hirotsugu, Miura, Katsuyuki, and Okayama, Akira

Subjects
COVID-19 pandemic, MARITAL status, LIVING alone, HOUSEHOLDS, AGE groups, LOGISTIC regression analysis
Abstract

Stay-at-home strategies taken during the COVID-19 pandemic changed our lifestyle drastically. Although marital status and household size are important social determinants of health that affect lifestyle, their impacts on lifestyle during the pandemic are still unclear. We aimed to evaluate the association between marital status, household size, and lifestyle changes during the first pandemic in Japan. Questionnaire surveys on lifestyle changes from before to during the first COVID-19 pandemic were conducted on October 2020 in Japan. Classified into age groups, multivariable logistic regression analysis was performed to examine the combined association of marital status and household size on lifestyle, adjusted for potential confounders including socioeconomic factors. In our prospective cohort study, 1928 participants were included. Among older participants, the singles living alone were likely to perceive more unhealthy lifestyle changes (45.8%), compared with the married (33.2%), and significantly associated with at least one unhealthy change [adjusted odds ratio (OR): 1.81, 95% confidence interval (CI): 1,18–2.78], mainly due to decreased physical activity and increased alcohol consumption. Meanwhile, the younger participants showed no significant association between marital status, household size, and unhealthy changes, while those living alone had 2.87 times higher odds of weight gain (≥ 3 kg) than the married (adjusted OR: 2.87, 95% CI: 0.96–8.54) during the pandemic. Our findings suggest that older singles living alone are potentially vulnerable subgroups to drastic social changes which warrant special attention to prevent adverse health outcomes and additional burden on health systems in the following future. [ABSTRACT FROM AUTHOR]

Published
2023
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34. Association of Alcohol Consumption With Fat Deposition in a Community-Based Sample of Japanese Men: The Shiga Epidemiological Study of Subclinical Atherosclerosis (SESSA)

Author

Sumi, Masaki, Hisamatsu, Takashi, Fujiyoshi , Akira, Kadota, Aya, Miyagawa, Naoko, Kondo, Keiko, Kadowaki, Sayaka, Suzuki , Sentaro, Torii, Sayuki, Zaid Maryam, Sato, Atsushi, Arima, Hisatomi, Terada, Tomohiro, Miura, Katsuyuki, Ueshima , Hirotsugu, Horie Minoru, Nakano Yasutaka, Yamamoto Takashi, Hayashi Hideki, Ogawa Emiko, Maegawa Hiroshi, Miyazawa Itsuko, Murata Kiyoshi, Mitsunami Kenichi, Nozaki Kazuhiko, Tooyama Ikuo, Shiino Akihiko, Tsuru Teruhiko, Ogita Hisakazu, Shimizu Akio, Miyamatsu Naomi, Kita Toru, Kimura Takeshi, Nishio Yoshihiko, Nakamura Yasuyuki, Okamura Tomonori, Sekikawa Akira, Barinas-Mitchell Emma J. M., Edmundowicz Daniel, Ohkubo Takayoshi, Hozawa Atsushi, Murakami Yoshitaka, Okuda Nagako, Arima Hisatomi, Kita Yoshikuni, Hisamatsu Takashi, Higashiyama Aya, Nagasawa Shinya, Azuma Koichiro, Yanagita Masahiko, Abbott Robert D., Kadota Aya, Ohno Seiko, Fujiyoshi Akira, Takashima Naoyuki, Kadowaki Takashi, Kadowaki Sayaka, Miyagawa Naoko, Kondo Keiko, Torii Sayuki, Saito Yoshino, Suzuki Sentaro, Ito Takahiro, Satoh Atsushi, and Yamazoe Masahiro

Subjects
Adult, Male, medicine.medical_specialty, Alcohol Drinking, Epidemiology, alcohol consumption, Population, Adipose tissue, 030209 endocrinology & metabolism, Intra-Abdominal Fat, 03 medical and health sciences, 0302 clinical medicine, Japan, Internal medicine, medicine, Humans, 030212 general & internal medicine, visceral adipose tissue, Adverse effect, education, Nutrition, Aged, lcsh:R5-920, education.field_of_study, Anthropometry, business.industry, anthropometric obesity indice, Confounding, nutritional and metabolic diseases, General Medicine, Middle Aged, medicine.disease, fat deposition, Obesity, Subcutaneous Fat, Abdominal, Epidemiologic Studies, Cross-Sectional Studies, Population Surveillance, Original Article, lcsh:Medicine (General), Tomography, X-Ray Computed, business, Body mass index
Abstract

Background: Excessive alcohol intake has been shown to be associated with cardiovascular disease via metabolic pathways. However, the relationship between alcohol intake and obesity has not been fully elucidated. We aimed to examine the association of alcohol consumption with fat deposition and anthropometric measures. Methods: From 2006–2008, we conducted a cross-sectional study in a population-based sample of Japanese men aged 40 through 79 years. Areas of abdominal visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) were calculated using computed tomography imaging. Based on a questionnaire, we classified participants into five groups according to weekly alcohol consumption, excluding former drinkers: non-drinkers (0 g/week), 0.1–160.9, 161–321.9, 322–482.9, and ≥483 g/week. Multivariable linear regression was used to estimate adjusted means of obesity indices for each group. Results: We analyzed 998 men (mean age and body mass index [BMI], 63.8 years and 23.6 kg/m2, respectively). Higher weekly alcohol consumption was strongly and significantly associated with higher abdominal VAT area, percentage of VAT, and VAT-to-SAT ratio (all P for trend

Published
2019
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36. Predictors of lower limb fractures in general Japanese: NIPPON DATA90

Author

SAITO, Yoshino, MIURA, Katsuyuki, ARIMA, Hisatomi, HAYAKAWA, Takehito, TAKASHIMA, Naoyuki, KITA, Yoshikuni, OKUDA, Nagako, FUJIYOSHI, Akira, IWAHORI, Toshiyuki, MIYAGAWA, Naoko, KONDO, Keiko, TORII, Sayuki, KADOTA, Aya, OHKUBO, Takayoshi, OKAYAMA, Akira, OKAMURA, Tomonori, UESHIMA, Hirotsugu, and NIPPON DATA90 Research Group

Subjects
Male, Asia, Databases, Factual, Epidemiology, Physiology, Science, Body Mass Index, Geographical Locations, Fractures, Bone, Japan, Risk Factors, Medicine and Health Sciences, Humans, Public and Occupational Health, Prospective Studies, Femur, Musculoskeletal System, Skeleton, Aged, Proportional Hazards Models, Nutrition, Multidisciplinary, Incidence, Traumatic Injury Risk Factors, Body Weight, Age Factors, Biology and Life Sciences, Middle Aged, Nutrition Surveys, Diet, Lower Extremity, Physiological Parameters, Food, Body Limbs, Medical Risk Factors, People and Places, Medicine, Female, Anatomy, Femoral Fractures, Research Article
Abstract

Objective:This study aimed to investigate the incidence rates and predictors of lower limb fractures in a general Japanese population., Methods:NIPPON DATA is a nationwide, long-term, prospective cohort study of individuals who participated in the National Cardiovascular Survey Japan and the National Nutrition Survey in 1990. Overall, 3,134 individuals (1,827 women, 1,307 men) who participated in follow-up assessments in 1995, 2000, and/or 2006 were included in the present analysis. The outcomes of this study were lower limb fractures (including proximal femur fractures)., Results:The mean age at baseline was 63.8 years in women and 63.1 years in men. The average body mass index (BMI) was 23.3 kg/m2 in women and 22.9 kg/m2 in men. During a mean follow-up of 12.1 years, 271 total lower limb fractures were observed. In women, older age, lower BMI, and less intake of vegetables were associated with increased risks of proximal femur fractures. With regard to the outcome of total lower limb fractures, less intake of vegetables and regular exercise were significant predictors in women. Calcium intake was not significantly associated with proximal femur or total lower limb fractures. There were no significant predictors of proximal femur or total lower limb fractures in men, except for age., Conclusions:Aging was a significant risk factor for proximal femur and total lower limb fractures in both men and women. With regard to modifiable risk factors, low BMI and low intake of vegetables were associated with increased risks of proximal femur and/or total lower limb fractures in the general population of Japanese women.

Published
2021

38. Association between Milk Intake and Incident Stroke among Japanese Community Dwellers: The Iwate-KENCO Study

Author

Tanno, Kozo, primary, Yonekura, Yuki, additional, Okuda, Nagako, additional, Kuribayashi, Toru, additional, Yabe, En, additional, Tsubota-Utsugi, Megumi, additional, Omama, Shinichi, additional, Onoda, Toshiyuki, additional, Ohsawa, Masaki, additional, Ogasawara, Kuniaki, additional, Tanaka, Fumitaka, additional, Asahi, Koichi, additional, Itabashi, Ryo, additional, Ito, Shigeki, additional, Ishigaki, Yasushi, additional, Takahashi, Fumiaki, additional, Koshiyama, Makoto, additional, Sasaki, Ryohei, additional, Fujimaki, Daisuke, additional, Takanashi, Nobuyuki, additional, Takusari, Eri, additional, Sakata, Kiyomi, additional, and Okayama, Akira, additional

Published
2021
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42. Cumulative impact of axial, structural, and repolarization ECG findings on long-term cardiovascular mortality among healthy individuals in Japan: National Integrated Project for Prospective Observation of Non-Communicable Disease and its Trends in the Aged, 1980 and 1990

Author

Inohara, Taku, Kohsaka, Shun, Okamura, Tomonori, Watanabe, Makoto, Nakamura, Yasuyuki, Higashiyama, Aya, Kadota, Aya, Okuda, Nagako, Murakami, Yoshitaka, Ohkubo, Takayoshi, Miura, Katsuyuki, Okayama, Akira, and Ueshima, Hirotsugu

Published
2014
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43. Differences Between Coronary Artery Calcification and Aortic Artery Calcification in Relation to Cardiovascular Disease Risk Factors in Japanese Men

Author

Kimani Cecilia, Kadota Aya, Miura Katsuyuki, Fujiyoshi Akira, Zaid Maryam, Kadowaki Sayaka, Hisamatsu Takashi, Arima Hisatomi, Horie Minoru, Ueshima Hirotsugu, Yamamoto Takashi, Maegawa Hiroshi, Murata Kiyoshi, Nozaki Kazuhiko, Shiino Akihiko, Toyama Ikuo, Tsuru Teruhiko, Ogita Hisakazu, Takashima Naoyuki, Kadowaki Takashi, Miyamatsu Naomi, Miyagawa Naoko, Torii Sayuki, Hayashi Hideki, Nakano Yasutaka, Ogawa Emiko, Miyazawa Itsuko, Shimizu Akio, Abbott Robert D., Kondo Keiko, Suzuki Sentaro, Ito Takahiro, Andoh Akira, Kunimura Ayako, Nishio Yoshihiko, Mitsunami Kenichi, Kita Toru, Kimura Takeshi, Tabara Yasuharu, Nakamura Yasuyuki, Okamura Tomonori, Sekikawa Akira, Barinas-Mitchell Emma J. M., Ohkubo Takayoshi, Kita Yoshikuni, Murakami Yoshitaka, Hozawa Atsushi, Okuda Nagako, Higashiyama Aya, Ohno Seiko, Nagasawa Shinya, Yamazo Masahiro, Saito Yoshino, Edmundowicz Daniel, Satoh Atsushi, Azuma Koichiro, Yanagita Masahiko, Sawamura Tatsuya, and Igase Michiya

Subjects
Adult, Male, medicine.medical_specialty, Aortic Diseases, Renal function, Blood lipids, Coronary Artery Disease, 030204 cardiovascular system & hematology, Coronary artery, Logistic regression, Calcification, 03 medical and health sciences, 0302 clinical medicine, Japan, Internal medicine, Internal Medicine, Humans, Medicine, cardiovascular diseases, Vascular Calcification, Generalized estimating equation, Aorta, Aged, 2. Zero hunger, business.industry, Incidence, Biochemistry (medical), nutritional and metabolic diseases, Odds ratio, Middle Aged, Prognosis, medicine.disease, Coronary Vessels, Aortic artery, Cardiovascular diseases, Risk factors, 3. Good health, Blood pressure, Cardiology, Original Article, Cardiology and Cardiovascular Medicine, business, Body mass index, 030217 neurology & neurosurgery, Follow-Up Studies
Abstract

Aims: Calcification in the coronary and aortic arteries has been linked to cardiovascular morbidity and mortality. The pathophysiological influence of aortic artery calcification (AAC) differs from that of coronary artery calcification (CAC). We aimed to compare the relationships between CAC and AAC and cardiovascular disease (CVD) risk factors. Methods: We examined a random sample of 1035 Japanese men aged 40–79 years. CAC and AAC were measured by computed tomography and scored according to the Agatston method. Using a logistic regression, we calculated the odds ratio (OR) as being in the highest quintile (Q5) of the calcification score compared to the lower quintiles (Q1–Q4) per 1 standard deviation higher CVD risk factor. Models were simultaneously adjusted for age, body mass index (BMI), systolic blood pressure, smoking (pack-year), alcohol intake, hemoglobin A1c, uric acid, estimated glomerular filtration rate (eGFR), serum lipids, and C-reactive protein. Differences in ORs were investigated using a generalized estimating equation. We performed a multiple linear regression using log-transformed CAC and AAC values as dependent variables. Results: CAC and AAC were independently associated with age (OR, 95% CI: 2.30 [1.77–2.98] for CAC and 3.48 [2.57–4.73] for AAC), p for difference < 0.001), systolic blood pressure (1.29 [1.08–1.53] and 1.28 [1.07–1.54], p for difference = 0.270), and smoking (1.22, [1.04–1.43] and 1.34 [1.13–1.58]) p for difference = 0.071). Alcohol correlated with AAC only (1.17 [0.97–1.41] for CAC and 1.42 [1.16–1.73] for AAC, p for difference = 0.020). Conclusions: CAC and AAC were associated with similar CVD risk factors. The strength of association slightly differed between CAC and AAC.

Published
2019

44. Association between Milk Intake and Incident Stroke among Japanese Community Dwellers : The Iwate-KENCO Study

Author

TANNO, Kozo, YONEKURA, Yuki, OKUDA, Nagako, KURIBAYASHI, Toru, YABE, En, TSUBOTA-UTSUGI, Megumi, OMAMA, Shinichi, ONODA, Toshiyuki, OHSAWA, Masaki, OGASAWARA, Kuniaki, TANAKA, Fumitaka, ASAHI, Koichi, ITABASHI, Ryo, ITO, Shigeki, ISHIGAKI, Yasushi, TAKAHASHI, Fumiaki, KOSHIYAMA, Makoto, SASAKI, Ryohei, FUJIMAKI, Daisuke, TAKANASHI, Nobuyuki, TAKUSARI, Eri, SAKATA, Kiyomi, OKAYAMA, Akira, TANNO, Kozo, YONEKURA, Yuki, OKUDA, Nagako, KURIBAYASHI, Toru, YABE, En, TSUBOTA-UTSUGI, Megumi, OMAMA, Shinichi, ONODA, Toshiyuki, OHSAWA, Masaki, OGASAWARA, Kuniaki, TANAKA, Fumitaka, ASAHI, Koichi, ITABASHI, Ryo, ITO, Shigeki, ISHIGAKI, Yasushi, TAKAHASHI, Fumiaki, KOSHIYAMA, Makoto, SASAKI, Ryohei, FUJIMAKI, Daisuke, TAKANASHI, Nobuyuki, TAKUSARI, Eri, SAKATA, Kiyomi, and OKAYAMA, Akira

Abstract

We aimed to evaluate the association between the milk consumption and incident stroke in a Japanese population, where milk consumption is lower than that of Western countries. In total, 14,121 participants (4253 men and 9868 women) aged 40–69 years, free from cardiovascular diseases (CVD) were prospectively followed for 10.7 years. Participants were categorized into four groups according to the milk intake frequency obtained from a brief-type self-administered diet questionnaire. The adjusted HRs of total stroke, ischemic stroke and haemorrhagic stroke associated with milk intake frequency were calculated using the Cox proportional hazards model. During the follow-up, 478 stroke cases were detected (208 men and 270 women). Compared to women with a milk intake of <2 cups/week, those with an intake of 7 to <12 cups/week had a significantly low risk of ischemic stroke in a model adjusting CVD risk factors; the HR (95% CI) was 0.53 (0.32–0.88). No significant associations were found in men. This study suggested that milk intake of 7 to <12 cups/week decreased the risk of ischemic stroke in Japanese women. Milk intake of about 1 to <2 cups/day may be effective in the primary prevention of ischemic stroke in a population with low milk intake

Published
2021

46. Interaction between dietary marine-derived n-3 fatty acids intake and J-point elevation on the risk of cardiac death: a 24-year follow-up of Japanese men

Author

Hisamatsu, Takashi, Miura, Katsuyuki, Ohkubo, Takayoshi, Yamamoto, Takashi, Fujiyoshi, Akira, Miyagawa, Naoko, Kadota, Aya, Takashima, Naoyuki, Okuda, Nagako, Matsumura, Yasuhiro, Yoshita, Katsushi, Kita, Yoshikuni, Murakami, Yoshitaka, Nakamura, Yasuyuki, Okamura, Tomonori, Horie, Minoru, Okayama, Akira, and Ueshima, Hirotsugu

Published
2013
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48. Relationship Between Calcium Intake and Impaired Activities of Daily Living in a Japanese Population: NIPPON DATA90

Author

Kogure, Mana, primary, Tsuchiya, Naho, additional, Narita, Akira, additional, Hirata, Takumi, additional, Nakaya, Naoki, additional, Nakamura, Tomohiro, additional, Hozawa, Atsushi, additional, Hayakawa, Takehito, additional, Okuda, Nagako, additional, Miyagawa, Naoko, additional, Kadota, Aya, additional, Ohkubo, Takayoshi, additional, Murakami, Yoshitaka, additional, Sakata, Kiyomi, additional, Miura, Katsuyuki, additional, Okayama, Akira, additional, Okamura, Tomonori, additional, and Ueshima, Hirotsugu, additional

Published
2021
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49. Alcohol drinking and brain morphometry in apparently healthy community-dwelling Japanese men

Author

Syaifullah, Ali Haidar, primary, Shiino, Akihiko, additional, Fujiyoshi, Akira, additional, Kadota, Aya, additional, Kondo, Keiko, additional, Ito, Takahiro, additional, Segawa, Hiroyoshi, additional, Moniruzzaman, Mohammad, additional, Waki, Takashi, additional, Miyagawa, Naoko, additional, Tooyama, Ikuo, additional, Ueshima, Hirotsugu, additional, Miura, Katsuyuki, additional, Horie, Minoru, additional, Nakagawa, Yoshihisa, additional, Yamamoto, Takashi, additional, Nakano, Yasutaka, additional, Ogawa, Emiko, additional, Maegawa, Hiroshi, additional, Morino, Katsutaro, additional, Miyazawa, Itsuko, additional, Watanabe, Yoshiyuki, additional, Nozaki, Kazuhiko, additional, Andoh, Akira, additional, Tsuru, Teruhiko, additional, Ogita, Hisakazu, additional, Miyamatsu, Naomi, additional, Nakamura, Yasuyuki, additional, Torii, Sayuki, additional, Kadowaki, Takashi, additional, Kadowaki, Sayaka, additional, Suzuki, Sentaro, additional, Kunimura, Ayako, additional, Higashiyama, Aya, additional, Okamura, Tomonori, additional, Azuma, Koichiro, additional, Sawamura, Tatsuya, additional, Igase, Michiya, additional, Tabara, Yasuharu, additional, Sekikawa, Akira, additional, Barinas-Mitchell, Emma J.M., additional, Edmundowicz, Daniel, additional, Ohkubo, Takayoshi, additional, Hozawa, Atsushi, additional, Murakami, Yoshitaka, additional, Okuda, Nagako, additional, Arima, Hisatomi, additional, Satoh, Atsushi, additional, Kita, Yoshikuni, additional, Hisamatsu, Takashi, additional, Yanagita, Masahiko, additional, Abbott, Robert D., additional, Ohno, Seiko, additional, Takashima, Naoyuki, additional, Zaid, Maryam, additional, and Saito, Yoshino, additional

Published
2021
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50. Food Sources of Dietary Potassium in the Adult Japanese Population: The International Study of Macro-/Micronutrients and Blood Pressure (INTERMAP)

Author

Okuda, Nagako, primary, Okayama, Akira, additional, Miura, Katsuyuki, additional, Yoshita, Katsushi, additional, Miyagawa, Naoko, additional, Saitoh, Shigeyuki, additional, Nakagawa, Hideaki, additional, Sakata, Kiyomi, additional, Chan, Queenie, additional, Elliott, Paul, additional, Ueshima, Hirotsugu, additional, and Stamler, Jeremiah, additional

Published
2020
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