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Your search keyword '"O. Tobaldini"' showing total 4 results
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4 results on '"O. Tobaldini"'

1. Pathophysiology CKD 5D

Author

M. Adamczak, A. Wiecek, L. Nowak, A. E. Grzegorzewska, L. Niepolski, D. Pajzderski, W. A. A. A. Mohamed, F. M. Khamis Zaki, W. H. M. Bekhit, I. S. Sherif, C.-C. Lin, H.-Y. Chen, Y.-L. Chiu, S.-P. Hsu, M.-F. Pai, J.-Y. Yang, Y.-S. Peng, T.-J. Tsai, K.-D. Wu, S. Shojai, U. Udayaraj, P. Shojai, R. Zwiech, A. Bruzda-Zwiech, K. Musial, D. Zwolinska, W. Piotr M., A. Mostowska, P. P. Jagodzinski, V. Ortalda, P. Tomei, T. Yabarek, O. Tobaldini, C. Gangemi, M. G. Messa, A. Lupo, L. Ebah, M. Nikam, A. Summers, I. Dawidowska, A. Jayanti, H. Wiig, P. Brenchley, S. Mitra, S. Mikami, T. Hamano, O. Iba, M. Toki, H. Mikami, Y. Takamitsu, M. Fujii, P. Dzekova-Vidimliski, A. Sikole, S. Gelev, G. Selim, L. Trajceska, S. Fujimoto, H. Inagaki, K. Fukudome, F. Ebihara, N. Yokota, Y. Sato, T. Akiba, S. Otsubo, K. Nitta, A. Rydzewska-Rosolowska, J. Gozdzikiewicz, J. Borawski, T. Hryszko, E. Koc-Zorawska, M. Mysliwiec, M. Arias, E. Banon-Maneus, A. Sole, N. Hierro-Garcia, J. Rovira, M. J. Ramirez-Bajo, L. F. Quintana, F. Diekmann, D. Moya-Rull, F. Maduell, J. M. Campistol, M. Erkmen Uyar, S. K. Toprak, H. Saglam, E. Tutal, M. Bay, O. Ilhan, S. Sezer, J. Malyszko, P. Kozminski, and E. Zbroch

Subjects
Transplantation, medicine.medical_specialty, Nephrology, business.industry, Medicine, business, Intensive care medicine, Pathophysiology
Published
2012

2. [Treatment of uremia in frail elderly patients: the issue of prolonged conservative management]

Author

V, De Biase, O, Tobaldini, S, Casarotti-Todeschini, and G, Gambaro

Subjects
Renal Dialysis, Frail Elderly, Humans, Kidney Failure, Chronic, Aged, Uremia
Abstract

The chronic use of renal replacement therapy in frail elderly patients sometimes provides no tangible benefits and may even have a negative fallout on their quality of life, making prolonged conservative management a reasonable option. However, this is mostly a feeling, since very few papers have addressed this issue and there is no evidence-based medicine related to it. On the other hand, ethical issues are extraordinarily relevant and in this clinical setting extend beyond topics such as end-of-life care and advance care planning. It is evident that clinical decision-making in frail elderly patients with endstage renal disease may be very difficult and needs to be supported by ad hoc clinical trials. In the meantime, the ethical issues must be discussed in society.

Published
2007

3. Prolonged conservative treatment for frail elderly patients with end-stage renal disease: the Verona experience.

Author

De Biase V, Tobaldini O, Boaretti C, Abaterusso C, Pertica N, Loschiavo C, Trabucco G, Lupo A, and Gambaro G

Subjects
Aged, Aged, 80 and over, Female, Follow-Up Studies, Glomerular Filtration Rate, Guideline Adherence, Humans, Italy epidemiology, Kidney Failure, Chronic epidemiology, Kidney Failure, Chronic physiopathology, Length of Stay trends, Male, Morbidity trends, Quality of Life, Retrospective Studies, Survival Rate trends, Time Factors, Treatment Outcome, Diuretics therapeutic use, Erythropoietin therapeutic use, Frail Elderly, Furosemide therapeutic use, Kidney Failure, Chronic therapy, Renal Dialysis methods
Abstract

Background: In frail elderly patients, the chronic use of renal replacement therapy sometimes affords no tangible benefits and may even negatively affect their quality of life (Qol), making prolonged conservative management a reasonable option., Methods: This observational, uncontrolled study was conducted on 11 end-stage renal disease patients over 75 years of age, on prolonged conservative treatment with a follow-up of at least 6 months, to assess compliance with the Italian clinical guidelines concerning the treatment of renal failure, comorbidities, hospital stays, and several psychometric and Qol indicators in the patients and their caregivers., Results: We found a substantial compliance with the targets recommended in the guidelines, a moderate tendency for disease progression and satisfactory psychometric and Qol parameters, which proved much the same as those observed in a parallel (uncontrolled) group of patients on haemodialysis., Conclusions: Our study shows that a conservative strategy is feasible for frail uraemic patients, achieving acceptable clinical results and a Qol comparable with patients on haemodialysis. The study also provides indications on how to plan trials on this topic, to obtain the evidence needed to guide the difficult choice of whether to recommend dialysis or conservative treatment for such frail patients.

Published
2008
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4. [Treatment of uremia in frail elderly patients: the issue of prolonged conservative management].

Author

De Biase V, Tobaldini O, Casarotti-Todeschini S, and Gambaro G

Subjects
Aged, Humans, Frail Elderly, Kidney Failure, Chronic therapy, Renal Dialysis ethics, Uremia therapy
Abstract

The chronic use of renal replacement therapy in frail elderly patients sometimes provides no tangible benefits and may even have a negative fallout on their quality of life, making prolonged conservative management a reasonable option. However, this is mostly a feeling, since very few papers have addressed this issue and there is no evidence-based medicine related to it. On the other hand, ethical issues are extraordinarily relevant and in this clinical setting extend beyond topics such as end-of-life care and advance care planning. It is evident that clinical decision-making in frail elderly patients with endstage renal disease may be very difficult and needs to be supported by ad hoc clinical trials. In the meantime, the ethical issues must be discussed in society.

Published
2007

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