Author: "O J, Han" - Searchworks@Jio Institute Digital Library Search Results

Author: K M, Kim, O J, Han, M S, Kang, and J Y, Huh
Subjects: Adult, Base Sequence, Genotype, Histocompatibility Testing, Gene Expression, Exons, Sequence Analysis, DNA, Polymerase Chain Reaction, Polymorphism, Single Nucleotide, Tissue Donors, Amino Acid Substitution, Asian People, HLA-A2 Antigen, Humans, Female, Cord Blood Stem Cell Transplantation, Codon, Sequence Alignment, Alleles
Abstract: A*02:687 showed one nucleotide difference with A*02:01:01:01 resulting in an amino acid change.
Published: 2017

Author: K. M. Kim, J. Y. Huh, O. J. Han, and M. S. Kang
Subjects: 0301 basic medicine, Immunology, Biology, HLA-A, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Cord blood, Genetics, Immunology and Allergy, Sequence-based Typing, Allele, 030215 immunology
Published: 2017
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Author: K M, Kim, O J, Han, M S, Kang, and J Y, Huh
Subjects: Base Sequence, HLA-A Antigens, Histocompatibility Testing, Republic of Korea, Humans, Female, Exons, Fetal Blood, Alleles
Abstract: The new allele A*33:102 showed two nucleotide differences with A*33:03:01 in exon 3.
Published: 2016

Author: S S, Hong, O J, Han, M S, Kang, and J Y, Huh
Subjects: Base Sequence, Genotype, Histocompatibility Testing, Molecular Sequence Data, Exons, Sequence Analysis, DNA, Polymerase Chain Reaction, Polymorphism, Single Nucleotide, Tissue Donors, HLA-B Antigens, Republic of Korea, Humans, Female, Cord Blood Stem Cell Transplantation, Alleles
Abstract: The new allele B*59:09 showed two nucleotide differences with B*59:01:01:01 in exon 3.
Published: 2015

Author: M S Kang, J Y Huh, O J Han, and S S Hong
Subjects: Genetics, Cord blood, Immunology, Immunology and Allergy, General Medicine, Allele, Sequence-based Typing, Biology, Biochemistry, HLA-B
Published: 2015
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Author: O J, Han, K H, Joe, S W, Kim, H S, Lee, N S, Kwon, K J, Baek, and H Y, Yun
Subjects: Cell Survival, Drug Resistance, MAP Kinase Kinase Kinase 5, MAP Kinase Kinase Kinases, Nitric Oxide, PC12 Cells, p38 Mitogen-Activated Protein Kinases, Rats, Enzyme Activation, Mutation, Animals, Nitric Oxide Donors, Enzyme Inhibitors, Mitogen-Activated Protein Kinases, Phosphorylation, Genes, Dominant
Abstract: Although nitric oxide (NO) plays key signaling roles in the nervous systems, excess NO leads to cell death. In this study, the involvement of p38 mitogen-activated protein kinase (p38 MAPK) and apoptosis signal-regulating kinase-1 (ASK1) in NO-induced cell death was investigated in PC12 cells. NO donor transiently activated p38 MAPK in the wild type parental PC12 cells, whereas the p38 MAPK activation was abolished in NO-resistant PC12 cells (PC 12-NO-R). p38 MAPK inhibitors protected the cells against NO-induced death, whereas the inhibitors were not significantly protective against the cytotoxicity of reactive oxygen species. Stable transfection with dominant negative p38 MAPK mutant reduced NO-induced cell death. Stable transfection with dominant negative mutant of ASK1 attenuated NO-stimulated activation of p38 MAPK and decreased NO-induced cell death. These results suggest that p38 MAPK and its upstream regulator ASK1 are involved in NO-induced PC12 cell death.
Published: 2001

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