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Multi-spectral imaging, which simultaneously captures the spatial and spectral information of a scene, is widely used across diverse fields, including remote sensing, biomedical imaging, and agricultural monitoring. Here, we introduce a snapshot multi-spectral imaging approach employing a standard monochrome image sensor with no additional spectral filters or customized components. Our system leverages the inherent chromatic aberration of wavelength-dependent defocusing as a natural source of physical encoding of multi-spectral information; this encoded image information is rapidly decoded via a deep learning-based multi-spectral Fourier Imager Network (mFIN). We experimentally tested our method with six illumination bands and demonstrated an overall accuracy of 92.98% for predicting the illumination channels at the input and achieved a robust multi-spectral image reconstruction on various test objects. This deep learning-powered framework achieves high-quality multi-spectral image reconstruction using snapshot image acquisition with a monochrome image sensor and could be useful for applications in biomedicine, industrial quality control, and agriculture, among others., Comment: 22 Pages, 7 Figures

Large Language Models (LLMs) have demonstrated impressive capabilities across a range of natural language processing tasks. In particular, improvements in reasoning abilities and the expansion of context windows have opened new avenues for leveraging these powerful models. NL2SQL is challenging in that the natural language question is inherently ambiguous, while the SQL generation requires a precise understanding of complex data schema and semantics. One approach to this semantic ambiguous problem is to provide more and sufficient contextual information. In this work, we explore the performance and the latency trade-offs of the extended context window (a.k.a., long context) offered by Google's state-of-the-art LLM (\textit{gemini-1.5-pro}). We study the impact of various contextual information, including column example values, question and SQL query pairs, user-provided hints, SQL documentation, and schema. To the best of our knowledge, this is the first work to study how the extended context window and extra contextual information can help NL2SQL generation with respect to both accuracy and latency cost. We show that long context LLMs are robust and do not get lost in the extended contextual information. Additionally, our long-context NL2SQL pipeline based on Google's \textit{gemini-pro-1.5} achieve a strong performance with 67.41\% on BIRD benchmark (dev) without finetuning and expensive self-consistency based techniques., Comment: 14 pages, 10 figures

This roadmap consolidates recent advances while exploring emerging applications, reflecting the remarkable diversity of hardware platforms, neuromorphic concepts, and implementation philosophies reported in the field. It emphasizes the critical role of cross-disciplinary collaboration in this rapidly evolving field.

We study relatively uniformly continuous operator semigroups on ordered vector spaces and extend several recent results obtained by M. Kramar Fijavz, M. Kandic, M. Kaplin, and J. Gluck in the vector lattice setting to ordered vector spaces with generating cones.

This paper investigates cash productivity as a signal for future stock performance, building on the cash-return framework of Faulkender and Wang (2006). Using financial and market data from WRDS, we calculate cash returns as a proxy for operational efficiency and evaluate a long-only strategy applied to Nasdaq-listed non-financial firms. Results show limited predictive power across the broader Nasdaq universe but strong performance in a handpicked portfolio, which achieves significant positive alpha after controlling for the Fama-French three factors. These findings underscore the importance of refined universe selection. While promising, the strategy requires further validation, including the incorporation of transaction costs and performance testing across economic cycles. Our results suggest that cash productivity, when combined with other complementary signals and careful universe selection, can be a valuable tool for generating excess returns.

We present a broadband and polarization-insensitive unidirectional imager that operates at the visible part of the spectrum, where image formation occurs in one direction while in the opposite direction, it is blocked. This approach is enabled by deep learning-driven diffractive optical design with wafer-scale nano-fabrication using high-purity fused silica to ensure optical transparency and thermal stability. Our design achieves unidirectional imaging across three visible wavelengths (covering red, green and blue parts of the spectrum), and we experimentally validated this broadband unidirectional imager by creating high-fidelity images in the forward direction and generating weak, distorted output patterns in the backward direction, in alignment with our numerical simulations. This work demonstrates the wafer-scale production of diffractive optical processors, featuring 16 levels of nanoscale phase features distributed across two axially aligned diffractive layers for visible unidirectional imaging. This approach facilitates mass-scale production of ~0.5 billion nanoscale phase features per wafer, supporting high-throughput manufacturing of hundreds to thousands of multi-layer diffractive processors suitable for large apertures and parallel processing of multiple tasks. Our design can seamlessly integrate into conventional optical systems, broadening its applicability in fields such as security, defense, and telecommunication. Beyond broadband unidirectional imaging in the visible spectrum, this study establishes a pathway for artificial-intelligence-enabled diffractive optics with versatile applications, signaling a new era in optical device functionality with industrial-level massively scalable fabrication., Comment: 23 Pages, 6 Figures

Democratizing biomarker testing at the point-of-care requires innovations that match laboratory-grade sensitivity and precision in an accessible format. Here, we demonstrate high-sensitivity detection of cardiac troponin I (cTnI) through innovations in chemiluminescence-based sensing, imaging, and deep learning-driven analysis. This chemiluminescence vertical flow assay (CL-VFA) enables rapid, low-cost, and precise quantification of cTnI, a key cardiac protein for assessing heart muscle damage and myocardial infarction. The CL-VFA integrates a user-friendly chemiluminescent paper-based sensor, a polymerized enzyme-based conjugate, a portable high-performance CL reader, and a neural network-based cTnI concentration inference algorithm. The CL-VFA measures cTnI over a broad dynamic range covering six orders of magnitude and operates with 50 uL of serum per test, delivering results in 25 min. This system achieves a detection limit of 0.16 pg/mL with an average coefficient of variation under 15%, surpassing traditional benchtop analyzers in sensitivity by an order of magnitude. In blinded validation, the computational CL-VFA accurately measured cTnI concentrations in patient samples, demonstrating a robust correlation against a clinical-grade FDA-cleared analyzer. These results highlight the potential of CL-VFA as a robust diagnostic tool for accessible, rapid cardiac biomarker testing that meets the needs of diverse healthcare settings, from emergency care to underserved regions., Comment: 24 Pages, 4 Figures

Unidirectional optical systems enable selective control of light through asymmetric processing of radiation, effectively transmitting light in one direction while blocking unwanted propagation in the opposite direction. Here, we introduce a reciprocal diffractive unidirectional focusing design based on linear and isotropic diffractive layers that are structured. Using deep learning-based optimization, a cascaded set of diffractive layers are spatially engineered at the wavelength scale to focus light efficiently in the forward direction while blocking it in the opposite direction. The forward energy focusing efficiency and the backward energy suppression capabilities of this unidirectional architecture were demonstrated under various illumination angles and wavelengths, illustrating the versatility of our polarization-insensitive design. Furthermore, we demonstrated that these designs are resilient to adversarial attacks that utilize wavefront engineering from outside. Experimental validation using terahertz radiation confirmed the feasibility of this diffractive unidirectional focusing framework. Diffractive unidirectional designs can operate across different parts of the electromagnetic spectrum by scaling the resulting diffractive features proportional to the wavelength of light and will find applications in security, defense, and optical communication, among others., Comment: 20 Pages, 6 Figures

Extended Reality (XR) services are set to transform applications over 5th and 6th generation wireless networks, delivering immersive experiences. Concurrently, Artificial Intelligence (AI) advancements have expanded their role in wireless networks, however, trust and transparency in AI remain to be strengthened. Thus, providing explanations for AI-enabled systems can enhance trust. We introduce Value Function Factorization (VFF)-based Explainable (X) Multi-Agent Reinforcement Learning (MARL) algorithms, explaining reward design in XR codec adaptation through reward decomposition. We contribute four enhancements to XMARL algorithms. Firstly, we detail architectural modifications to enable reward decomposition in VFF-based MARL algorithms: Value Decomposition Networks (VDN), Mixture of Q-Values (QMIX), and Q-Transformation (Q-TRAN). Secondly, inspired by multi-task learning, we reduce the overhead of vanilla XMARL algorithms. Thirdly, we propose a new explainability metric, Reward Difference Fluctuation Explanation (RDFX), suitable for problems with adjustable parameters. Lastly, we propose adaptive XMARL, leveraging network gradients and reward decomposition for improved action selection. Simulation results indicate that, in XR codec adaptation, the Packet Delivery Ratio reward is the primary contributor to optimal performance compared to the initial composite reward, which included delay and Data Rate Ratio components. Modifications to VFF-based XMARL algorithms, incorporating multi-headed structures and adaptive loss functions, enable the best-performing algorithm, Multi-Headed Adaptive (MHA)-QMIX, to achieve significant average gains over the Adjust Packet Size baseline up to 10.7%, 41.4%, 33.3%, and 67.9% in XR index, jitter, delay, and Packet Loss Ratio (PLR), respectively., Comment: 15 pages, 14 figures, Submitted to TCCN

Imaging mass spectrometry (IMS) is a powerful tool for untargeted, highly multiplexed molecular mapping of tissue in biomedical research. IMS offers a means of mapping the spatial distributions of molecular species in biological tissue with unparalleled chemical specificity and sensitivity. However, most IMS platforms are not able to achieve microscopy-level spatial resolution and lack cellular morphological contrast, necessitating subsequent histochemical staining, microscopic imaging and advanced image registration steps to enable molecular distributions to be linked to specific tissue features and cell types. Here, we present a virtual histological staining approach that enhances spatial resolution and digitally introduces cellular morphological contrast into mass spectrometry images of label-free human tissue using a diffusion model. Blind testing on human kidney tissue demonstrated that the virtually stained images of label-free samples closely match their histochemically stained counterparts (with Periodic Acid-Schiff staining), showing high concordance in identifying key renal pathology structures despite utilizing IMS data with 10-fold larger pixel size. Additionally, our approach employs an optimized noise sampling technique during the diffusion model's inference process to reduce variance in the generated images, yielding reliable and repeatable virtual staining. We believe this virtual staining method will significantly expand the applicability of IMS in life sciences and open new avenues for mass spectrometry-based biomedical research., Comment: 33 Pages, 6 Figures

Noninvasive optical imaging modalities can probe patient's tissue in 3D and over time generate gigabytes of clinically relevant data per sample. There is a need for AI models to analyze this data and assist clinical workflow. The lack of expert labelers and the large dataset required (>100,000 images) for model training and tuning are the main hurdles in creating foundation models. In this paper we introduce FoundationShift, a method to apply any AI model from computational pathology without retraining. We show our method is more accurate than state of the art models (SAM, MedSAM, SAM-Med2D, CellProfiler, Hover-Net, PLIP, UNI and ChatGPT), with multiple imaging modalities (OCT and RCM). This is achieved without the need for model retraining or fine-tuning. Applying our method to noninvasive in vivo images could enable physicians to readily incorporate optical imaging modalities into their clinical practice, providing real time tissue analysis and improving patient care.

Coronary artery disease (CAD), one of the leading causes of mortality worldwide, necessitates effective risk assessment strategies, with coronary artery calcium (CAC) scoring via computed tomography (CT) being a key method for prevention. Traditional methods, primarily based on UNET architectures implemented on pre-built models, face challenges like the scarcity of annotated CT scans containing CAC and imbalanced datasets, leading to reduced performance in segmentation and scoring tasks. In this study, we address these limitations by incorporating the self-supervised learning (SSL) technique of DINO (self-distillation with no labels), which trains without requiring CAC-specific annotations, enhancing its robustness in generating distinct features. The DINO-LG model, which leverages label guidance to focus on calcified areas, achieves significant improvements, with a sensitivity of 89% and specificity of 90% for detecting CAC-containing CT slices, compared to the standard DINO model's sensitivity of 79% and specificity of 77%. Additionally, false-negative and false-positive rates are reduced by 49% and 59%, respectively, instilling greater confidence in clinicians when ruling out calcification in low-risk patients and minimizing unnecessary imaging reviews by radiologists. Further, CAC scoring and segmentation tasks are conducted using a basic UNET architecture, applied specifically to CT slices identified by the DINO-LG model as containing calcified areas. This targeted approach enhances CAC scoring accuracy by feeding the UNET model with relevant slices, significantly improving diagnostic precision, reducing both false positives and false negatives, and ultimately lowering overall healthcare costs by minimizing unnecessary tests and treatments, presenting a valuable advancement in CAD risk assessment., Comment: Developed by Center for Applied Artificial Intelligence (CAAI), University of Kentucky

Federated learning (FL) is an innovative distributed artificial intelligence (AI) technique. It has been used for interdisciplinary studies in different fields such as healthcare, marketing and finance. However the application of FL in wireless networks is still in its infancy. In this work, we first overview benefits and concerns when applying FL to wireless networks. Next, we provide a new perspective on existing personalized FL frameworks by analyzing the relationship between cooperation and personalization in these frameworks. Additionally, we discuss the possibility of tuning the cooperation level with a choice-based approach. Our choice-based FL approach is a flexible and safe FL framework that allows participants to lower the level of cooperation when they feel unsafe or unable to benefit from the cooperation. In this way, the choice-based FL framework aims to address the safety and fairness concerns in FL and protect participants from malicious attacks.

Virtual staining of tissue offers a powerful tool for transforming label-free microscopy images of unstained tissue into equivalents of histochemically stained samples. This study presents a diffusion model-based super-resolution virtual staining approach utilizing a Brownian bridge process to enhance both the spatial resolution and fidelity of label-free virtual tissue staining, addressing the limitations of traditional deep learning-based methods. Our approach integrates novel sampling techniques into a diffusion model-based image inference process to significantly reduce the variance in the generated virtually stained images, resulting in more stable and accurate outputs. Blindly applied to lower-resolution auto-fluorescence images of label-free human lung tissue samples, the diffusion-based super-resolution virtual staining model consistently outperformed conventional approaches in resolution, structural similarity and perceptual accuracy, successfully achieving a super-resolution factor of 4-5x, increasing the output space-bandwidth product by 16-25-fold compared to the input label-free microscopy images. Diffusion-based super-resolved virtual tissue staining not only improves resolution and image quality but also enhances the reliability of virtual staining without traditional chemical staining, offering significant potential for clinical diagnostics., Comment: 26 Pages, 5 Figures

Generative models cover various application areas, including image, video and music synthesis, natural language processing, and molecular design, among many others. As digital generative models become larger, scalable inference in a fast and energy-efficient manner becomes a challenge. Here, we present optical generative models inspired by diffusion models, where a shallow and fast digital encoder first maps random noise into phase patterns that serve as optical generative seeds for a desired data distribution; a jointly-trained free-space-based reconfigurable decoder all-optically processes these generative seeds to create novel images (never seen before) following the target data distribution. Except for the illumination power and the random seed generation through a shallow encoder, these optical generative models do not consume computing power during the synthesis of novel images. We report the optical generation of monochrome and multi-color novel images of handwritten digits, fashion products, butterflies, and human faces, following the data distributions of MNIST, Fashion MNIST, Butterflies-100, and Celeb-A datasets, respectively, achieving an overall performance comparable to digital neural network-based generative models. To experimentally demonstrate optical generative models, we used visible light to generate, in a snapshot, novel images of handwritten digits and fashion products. These optical generative models might pave the way for energy-efficient, scalable and rapid inference tasks, further exploiting the potentials of optics and photonics for artificial intelligence-generated content., Comment: 24 Pages, 9 Figures

We developed a rapid scanning optical microscope, termed "BlurryScope", that leverages continuous image acquisition and deep learning to provide a cost-effective and compact solution for automated inspection and analysis of tissue sections. BlurryScope integrates specialized hardware with a neural network-based model to quickly process motion-blurred histological images and perform automated pathology classification. This device offers comparable speed to commercial digital pathology scanners, but at a significantly lower price point and smaller size/weight, making it ideal for fast triaging in small clinics, as well as for resource-limited settings. To demonstrate the proof-of-concept of BlurryScope, we implemented automated classification of human epidermal growth factor receptor 2 (HER2) scores on immunohistochemically (IHC) stained breast tissue sections, achieving concordant results with those obtained from a high-end digital scanning microscope. We evaluated this approach by scanning HER2-stained tissue microarrays (TMAs) at a continuous speed of 5 mm/s, which introduces bidirectional motion blur artifacts. These compromised images were then used to train our network models. Using a test set of 284 unique patient cores, we achieved blind testing accuracies of 79.3% and 89.7% for 4-class (0, 1+, 2+, 3+) and 2-class (0/1+ , 2+/3+) HER2 score classification, respectively. BlurryScope automates the entire workflow, from image scanning to stitching and cropping of regions of interest, as well as HER2 score classification. We believe BlurryScope has the potential to enhance the current pathology infrastructure in resource-scarce environments, save diagnostician time and bolster cancer identification and classification across various clinical environments., Comment: 18 Pages, 6 Figures

It is proved that: each collectively order continuous set of operators from an Archimedean OVS with a generating cone to an OVS is collectively order bounded; and each collectively order to norm bounded set of operators from an ordered Banach space with a closed generating cone to a normed space is norm bounded. Several applications to commutative operator semigroups on ordered vector spaces are given.

We introduce an all-optical system, termed the "lying mirror", to hide input information by transforming it into misleading, ordinary-looking patterns that effectively camouflage the underlying image data and deceive the observers. This misleading transformation is achieved through passive light-matter interactions of the incident light with an optimized structured diffractive surface, enabling the optical concealment of any form of secret input data without any digital computing. These lying mirror designs were shown to camouflage different types of input image data, exhibiting robustness against a range of adversarial manipulations, including random image noise as well as unknown, random rotations, shifts, and scaling of the object features. The feasibility of the lying mirror concept was also validated experimentally using a structured micro-mirror array along with multi-wavelength illumination at 480, 550 and 600 nm, covering the blue, green and red image channels. This framework showcases the power of structured diffractive surfaces for visual information processing and might find various applications in defense, security and entertainment., Comment: 21 Pages, 8 Figures

Distinguishing between swarming and swimming, the two principal forms of bacterial movement, holds significant conceptual and clinical relevance. This is because bacteria that exhibit swarming capabilities often possess unique properties crucial to the pathogenesis of infectious diseases and may also have therapeutic potential. Here, we report a deep learning-based swarming classifier that rapidly and autonomously predicts swarming probability using a single blurry image. Compared with traditional video-based, manually-processed approaches, our method is particularly suited for high-throughput environments and provides objective, quantitative assessments of swarming probability. The swarming classifier demonstrated in our work was trained on Enterobacter sp. SM3 and showed good performance when blindly tested on new swarming (positive) and swimming (negative) test images of SM3, achieving a sensitivity of 97.44% and a specificity of 100%. Furthermore, this classifier demonstrated robust external generalization capabilities when applied to unseen bacterial species, such as Serratia marcescens DB10 and Citrobacter koseri H6. It blindly achieved a sensitivity of 97.92% and a specificity of 96.77% for DB10, and a sensitivity of 100% and a specificity of 97.22% for H6. This competitive performance indicates the potential to adapt our approach for diagnostic applications through portable devices or even smartphones. This adaptation would facilitate rapid, objective, on-site screening for bacterial swarming motility, potentially enhancing the early detection and treatment assessment of various diseases, including inflammatory bowel diseases (IBD) and urinary tract infections (UTI)., Comment: 17 Pages, 4 Figures

Network slicing is a pivotal paradigm in wireless networks enabling customized services to users and applications. Yet, intelligent jamming attacks threaten the performance of network slicing. In this paper, we focus on the security aspect of network slicing over a deep transfer reinforcement learning (DTRL) enabled scenario. We first demonstrate how a deep reinforcement learning (DRL)-enabled jamming attack exposes potential risks. In particular, the attacker can intelligently jam resource blocks (RBs) reserved for slices by monitoring transmission signals and perturbing the assigned resources. Then, we propose a DRL-driven mitigation model to mitigate the intelligent attacker. Specifically, the defense mechanism generates interference on unallocated RBs where another antenna is used for transmitting powerful signals. This causes the jammer to consider these RBs as allocated RBs and generate interference for those instead of the allocated RBs. The analysis revealed that the intelligent DRL-enabled jamming attack caused a significant 50% degradation in network throughput and 60% increase in latency in comparison with the no-attack scenario. However, with the implemented mitigation measures, we observed 80% improvement in network throughput and 70% reduction in latency in comparison to the under-attack scenario.

In tackling the challenges of large language model (LLM) performance for Text-to-SQL tasks, we introduce CHASE-SQL, a new framework that employs innovative strategies, using test-time compute in multi-agent modeling to improve candidate generation and selection. CHASE-SQL leverages LLMs' intrinsic knowledge to generate diverse and high-quality SQL candidates using different LLM generators with: (1) a divide-and-conquer method that decomposes complex queries into manageable sub-queries in a single LLM call; (2) chain-of-thought reasoning based on query execution plans, reflecting the steps a database engine takes during execution; and (3) a unique instance-aware synthetic example generation technique, which offers specific few-shot demonstrations tailored to test questions.To identify the best candidate, a selection agent is employed to rank the candidates through pairwise comparisons with a fine-tuned binary-candidates selection LLM. This selection approach has been demonstrated to be more robust over alternatives. The proposed generators-selector framework not only enhances the quality and diversity of SQL queries but also outperforms previous methods. Overall, our proposed CHASE-SQL achieves the state-of-the-art execution accuracy of 73.0% and 73.01% on the test set and development set of the notable BIRD Text-to-SQL dataset benchmark, rendering CHASE-SQL the top submission of the leaderboard (at the time of paper submission).

Traffic Steering is a crucial technology for wireless networks, and multiple efforts have been put into developing efficient Machine Learning (ML)-enabled traffic steering schemes for Open Radio Access Networks (O-RAN). Given the swift emergence of novel ML techniques, conducting a timely survey that comprehensively examines the ML-based traffic steering schemes in O-RAN is critical. In this article, we provide such a survey along with a case study of hierarchical learning-enabled traffic steering in O-RAN. In particular, we first introduce the background of traffic steering in O-RAN and overview relevant state-of-the-art ML techniques and their applications. Then, we analyze the compatibility of the hierarchical learning framework in O-RAN and further propose a Hierarchical Deep-Q-Learning (h-DQN) framework for traffic steering. Compared to existing works, which focus on single-layer architecture with standalone agents, h-DQN decomposes the traffic steering problem into a bi-level architecture with hierarchical intelligence. The meta-controller makes long-term and high-level policies, while the controller executes instant traffic steering actions under high-level policies. Finally, the case study shows that the hierarchical learning approach can provide significant performance improvements over the baseline algorithms., Comment: Accepted for publication in IEEE Communications Magazine

Organ transplantation serves as the primary therapeutic strategy for end-stage organ failures. However, allograft rejection is a common complication of organ transplantation. Histological assessment is essential for the timely detection and diagnosis of transplant rejection and remains the gold standard. Nevertheless, the traditional histochemical staining process is time-consuming, costly, and labor-intensive. Here, we present a panel of virtual staining neural networks for lung and heart transplant biopsies, which digitally convert autofluorescence microscopic images of label-free tissue sections into their brightfield histologically stained counterparts, bypassing the traditional histochemical staining process. Specifically, we virtually generated Hematoxylin and Eosin (H&E), Masson's Trichrome (MT), and Elastic Verhoeff-Van Gieson (EVG) stains for label-free transplant lung tissue, along with H&E and MT stains for label-free transplant heart tissue. Subsequent blind evaluations conducted by three board-certified pathologists have confirmed that the virtual staining networks consistently produce high-quality histology images with high color uniformity, closely resembling their well-stained histochemical counterparts across various tissue features. The use of virtually stained images for the evaluation of transplant biopsies achieved comparable diagnostic outcomes to those obtained via traditional histochemical staining, with a concordance rate of 82.4% for lung samples and 91.7% for heart samples. Moreover, virtual staining models create multiple stains from the same autofluorescence input, eliminating structural mismatches observed between adjacent sections stained in the traditional workflow, while also saving tissue, expert time, and staining costs., Comment: 21 Pages, 5 Figures

Snell's law dictates the phenomenon of light refraction at the interface between two media. Here, we demonstrate, for the first time, arbitrary programming of light refraction through an engineered material where the direction of the output wave can be set independently for different directions of the input wave, covering arbitrarily selected permutations of light refraction between the input and output apertures. Formed by a set of cascaded transmissive layers with optimized phase profiles, this refractive function generator (RFG) spans only a few tens of wavelengths in the axial direction. In addition to monochrome RFG designs, we also report wavelength-multiplexed refractive functions, where a distinct refractive function is implemented at each wavelength through the same engineered material volume, i.e., the permutation of light refraction is switched from one desired function to another function by changing the illumination wavelength. As an experimental proof of concept, we demonstrate negative refractive function at the terahertz part of the spectrum using a 3D-printed material. Arbitrary programming of refractive functions enables new design capabilities for optical materials, devices and systems., Comment: 22 Pages, 10 Figures

In 5G networks, network slicing has emerged as a pivotal paradigm to address diverse user demands and service requirements. To meet the requirements, reinforcement learning (RL) algorithms have been utilized widely, but this method has the problem of overestimation and exploration-exploitation trade-offs. To tackle these problems, this paper explores the application of self-play ensemble Q-learning, an extended version of the RL-based technique. Self-play ensemble Q-learning utilizes multiple Q-tables with various exploration-exploitation rates leading to different observations for choosing the most suitable action for each state. Moreover, through self-play, each model endeavors to enhance its performance compared to its previous iterations, boosting system efficiency, and decreasing the effect of overestimation. For performance evaluation, we consider three RL-based algorithms; self-play ensemble Q-learning, double Q-learning, and Q-learning, and compare their performance under different network traffic. Through simulations, we demonstrate the effectiveness of self-play ensemble Q-learning in meeting the diverse demands within 21.92% in latency, 24.22% in throughput, and 23.63\% in packet drop rate in comparison with the baseline methods. Furthermore, we evaluate the robustness of self-play ensemble Q-learning and double Q-learning in situations where one of the Q-tables is affected by a malicious user. Our results depicted that the self-play ensemble Q-learning method is more robust against adversarial users and prevents a noticeable drop in system performance, mitigating the impact of users manipulating policies.

We discuss the geometric formulation of continuum defects consisting of dislocations and disclinations. After reviewing the metric affine geometry and the present geometric formulation of dislocation and disclination written in terms of torsion and full curvature (together with vanishing non-metricity), we give a new theory of them in a novel way in terms of torsion and non-metricity (together with vanishing full curvature), the so-called general teleparallel geometry. All calculations are performed by using the exterior algebra. We obtain continuity equations explicitly for dislocation density and disclination density.

Unidirectional imagers form images of input objects only in one direction, e.g., from field-of-view (FOV) A to FOV B, while blocking the image formation in the reverse direction, from FOV B to FOV A. Here, we report unidirectional imaging under spatially partially coherent light and demonstrate high-quality imaging only in the forward direction (A->B) with high power efficiency while distorting the image formation in the backward direction (B->A) along with low power efficiency. Our reciprocal design features a set of spatially engineered linear diffractive layers that are statistically optimized for partially coherent illumination with a given phase correlation length. Our analyses reveal that when illuminated by a partially coherent beam with a correlation length of ~1.5 w or larger, where w is the wavelength of light, diffractive unidirectional imagers achieve robust performance, exhibiting asymmetric imaging performance between the forward and backward directions - as desired. A partially coherent unidirectional imager designed with a smaller correlation length of less than 1.5 w still supports unidirectional image transmission, but with a reduced figure of merit. These partially coherent diffractive unidirectional imagers are compact (axially spanning less than 75 w), polarization-independent, and compatible with various types of illumination sources, making them well-suited for applications in asymmetric visual information processing and communication., Comment: 25 Pages, 8 Figures

Waveguide design is crucial in developing efficient light delivery systems, requiring meticulous material selection, precise manufacturing, and rigorous performance optimization, including dispersion engineering. Here, we introduce universal diffractive waveguide designs that can match the performance of any conventional dielectric waveguide and achieve various functionalities. Optimized using deep learning, our diffractive waveguide designs can be cascaded to each other to form any desired length and are comprised of transmissive diffractive surfaces that permit the propagation of desired guided modes with low loss and high mode purity. In addition to guiding the targeted modes along the propagation direction through cascaded diffractive units, we also developed various waveguide components and introduced bent diffractive waveguides, rotating the direction of mode propagation, as well as programmable mode filtering and mode splitting diffractive waveguide designs, showcasing the versatility of this platform. This diffractive waveguide framework was experimentally validated in the terahertz (THz) spectrum using 3D-printed diffractive layers to selectively pass certain spatial modes while rejecting others. Diffractive waveguides can be scaled to operate at different wavelengths, including visible and infrared parts of the spectrum, without the need for material dispersion engineering, providing an alternative to traditional waveguide components. This advancement will have potential applications in telecommunications, imaging, sensing and spectroscopy, among others., Comment: 38 Pages, 8 Figures

Gram staining has been one of the most frequently used staining protocols in microbiology for over a century, utilized across various fields, including diagnostics, food safety, and environmental monitoring. Its manual procedures make it vulnerable to staining errors and artifacts due to, e.g., operator inexperience and chemical variations. Here, we introduce virtual Gram staining of label-free bacteria using a trained deep neural network that digitally transforms darkfield images of unstained bacteria into their Gram-stained equivalents matching brightfield image contrast. After a one-time training effort, the virtual Gram staining model processes an axial stack of darkfield microscopy images of label-free bacteria (never seen before) to rapidly generate Gram staining, bypassing several chemical steps involved in the conventional staining process. We demonstrated the success of the virtual Gram staining workflow on label-free bacteria samples containing Escherichia coli and Listeria innocua by quantifying the staining accuracy of the virtual Gram staining model and comparing the chromatic and morphological features of the virtually stained bacteria against their chemically stained counterparts. This virtual bacteria staining framework effectively bypasses the traditional Gram staining protocol and its challenges, including stain standardization, operator errors, and sensitivity to chemical variations., Comment: 25 Pages, 5 Figures

The advance of diffusion-based generative models in recent years has revolutionized state-of-the-art (SOTA) techniques in a wide variety of image analysis and synthesis tasks, whereas their adaptation on image restoration, particularly within computational microscopy remains theoretically and empirically underexplored. In this research, we introduce a multi-scale generative model that enhances conditional image restoration through a novel exploitation of the Brownian Bridge process within wavelet domain. By initiating the Brownian Bridge diffusion process specifically at the lowest-frequency subband and applying generative adversarial networks at subsequent multi-scale high-frequency subbands in the wavelet domain, our method provides significant acceleration during training and sampling while sustaining a high image generation quality and diversity on par with SOTA diffusion models. Experimental results on various computational microscopy and imaging tasks confirm our method's robust performance and its considerable reduction in its sampling steps and time. This pioneering technique offers an efficient image restoration framework that harmonizes efficiency with quality, signifying a major stride in incorporating cutting-edge generative models into computational microscopy workflows.

Optical imaging and sensing systems based on diffractive elements have seen massive advances over the last several decades. Earlier generations of diffractive optical processors were, in general, designed to deliver information to an independent system that was separately optimized, primarily driven by human vision or perception. With the recent advances in deep learning and digital neural networks, there have been efforts to establish diffractive processors that are jointly optimized with digital neural networks serving as their back-end. These jointly optimized hybrid (optical+digital) processors establish a new "diffractive language" between input electromagnetic waves that carry analog information and neural networks that process the digitized information at the back-end, providing the best of both worlds. Such hybrid designs can process spatially and temporally coherent, partially coherent, or incoherent input waves, providing universal coverage for any spatially varying set of point spread functions that can be optimized for a given task, executed in collaboration with digital neural networks. In this article, we highlight the utility of this exciting collaboration between engineered and programmed diffraction and digital neural networks for a diverse range of applications. We survey some of the major innovations enabled by the push-pull relationship between analog wave processing and digital neural networks, also covering the significant benefits that could be reaped through the synergy between these two complementary paradigms., Comment: 30 Pages, 6 Figures

Optical continuous glucose monitoring (CGM) systems are emerging for personalized glucose management owing to their lower cost and prolonged durability compared to conventional electrochemical CGMs. Here, we report a computational CGM system, which integrates a biocompatible phosphorescence-based insertable biosensor and a custom-designed phosphorescence lifetime imager (PLI). This compact and cost-effective PLI is designed to capture phosphorescence lifetime images of an insertable sensor through the skin, where the lifetime of the emitted phosphorescence signal is modulated by the local concentration of glucose. Because this phosphorescence signal has a very long lifetime compared to tissue autofluorescence or excitation leakage processes, it completely bypasses these noise sources by measuring the sensor emission over several tens of microseconds after the excitation light is turned off. The lifetime images acquired through the skin are processed by neural network-based models for misalignment-tolerant inference of glucose levels, accurately revealing normal, low (hypoglycemia) and high (hyperglycemia) concentration ranges. Using a 1-mm thick skin phantom mimicking the optical properties of human skin, we performed in vitro testing of the PLI using glucose-spiked samples, yielding 88.8% inference accuracy, also showing resilience to random and unknown misalignments within a lateral distance of ~4.7 mm with respect to the position of the insertable sensor underneath the skin phantom. Furthermore, the PLI accurately identified larger lateral misalignments beyond 5 mm, prompting user intervention for re-alignment. The misalignment-resilient glucose concentration inference capability of this compact and cost-effective phosphorescence lifetime imager makes it an appealing wearable diagnostics tool for real-time tracking of glucose and other biomarkers., Comment: 24 Pages, 4 Figures

Intent-based network automation is a promising tool to enable easier network management however certain challenges need to be effectively addressed. These are: 1) processing intents, i.e., identification of logic and necessary parameters to fulfill an intent, 2) validating an intent to align it with current network status, and 3) satisfying intents via network optimizing functions like xApps and rApps in O-RAN. This paper addresses these points via a three-fold strategy to introduce intent-based automation for O-RAN. First, intents are processed via a lightweight Large Language Model (LLM). Secondly, once an intent is processed, it is validated against future incoming traffic volume profiles (high or low). Finally, a series of network optimization applications (rApps and xApps) have been developed. With their machine learning-based functionalities, they can improve certain key performance indicators such as throughput, delay, and energy efficiency. In this final stage, using an attention-based hierarchical reinforcement learning algorithm, these applications are optimally initiated to satisfy the intent of an operator. Our simulations show that the proposed method can achieve at least 12% increase in throughput, 17.1% increase in energy efficiency, and 26.5% decrease in network delay compared to the baseline algorithms., Comment: Accepted paper at WCNC 2025

Physical neural networks (PNNs) are a class of neural-like networks that leverage the properties of physical systems to perform computation. While PNNs are so far a niche research area with small-scale laboratory demonstrations, they are arguably one of the most underappreciated important opportunities in modern AI. Could we train AI models 1000x larger than current ones? Could we do this and also have them perform inference locally and privately on edge devices, such as smartphones or sensors? Research over the past few years has shown that the answer to all these questions is likely "yes, with enough research": PNNs could one day radically change what is possible and practical for AI systems. To do this will however require rethinking both how AI models work, and how they are trained - primarily by considering the problems through the constraints of the underlying hardware physics. To train PNNs at large scale, many methods including backpropagation-based and backpropagation-free approaches are now being explored. These methods have various trade-offs, and so far no method has been shown to scale to the same scale and performance as the backpropagation algorithm widely used in deep learning today. However, this is rapidly changing, and a diverse ecosystem of training techniques provides clues for how PNNs may one day be utilized to create both more efficient realizations of current-scale AI models, and to enable unprecedented-scale models., Comment: 29 pages, 4 figures

Extended Reality (XR) services will revolutionize applications over 5th and 6th generation wireless networks by providing seamless virtual and augmented reality experiences. These applications impose significant challenges on network infrastructure, which can be addressed by machine learning algorithms due to their adaptability. This paper presents a Multi- Agent Reinforcement Learning (MARL) solution for optimizing codec parameters of XR traffic, comparing it to the Adjust Packet Size (APS) algorithm. Our cooperative multi-agent system uses an Optimistic Mixture of Q-Values (oQMIX) approach for handling Cloud Gaming (CG), Augmented Reality (AR), and Virtual Reality (VR) traffic. Enhancements include an attention mechanism and slate-Markov Decision Process (MDP) for improved action selection. Simulations show our solution outperforms APS with average gains of 30.1%, 15.6%, 16.5% 50.3% in XR index, jitter, delay, and Packet Loss Ratio (PLR), respectively. APS tends to increase throughput but also packet losses, whereas oQMIX reduces PLR, delay, and jitter while maintaining goodput., Comment: 6 pages, 5 figures, 2 tables

Learning-based methods have become increasingly popular for solving vehicle routing problems due to their near-optimal performance and fast inference speed. Among them, the combination of deep reinforcement learning and graph representation allows for the abstraction of node topology structures and features in an encoder-decoder style. Such an approach makes it possible to solve routing problems end-to-end without needing complicated heuristic operators designed by domain experts. Existing research studies have been focusing on novel encoding and decoding structures via various neural network models to enhance the node embedding representation. Despite the sophisticated approaches applied, there is a noticeable lack of consideration for the graph-theoretic properties inherent to routing problems. Moreover, the potential ramifications of inter-nodal interactions on the decision-making efficacy of the models have not been adequately explored. To bridge this gap, we propose an adaptive Graph Attention Sampling with the Edges Fusion framework (GASE),where nodes' embedding is determined through attention calculation from certain highly correlated neighbourhoods and edges, utilizing a filtered adjacency matrix. In detail, the selections of particular neighbours and adjacency edges are led by a multi-head attention mechanism, contributing directly to the message passing and node embedding in graph attention sampling networks. Furthermore, we incorporate an adaptive actor-critic algorithm with policy improvements to expedite the training convergence. We then conduct comprehensive experiments against baseline methods on learning-based VRP tasks from different perspectives. Our proposed model outperforms the existing methods by 2.08\%-6.23\% and shows stronger generalization ability, achieving state-of-the-art performance on randomly generated instances and real-world datasets., Comment: 24 pages, 5figures, 4 tables