80 results on '"O'uchi T"'
Search Results
2. High signal of the striatum in sporadic Creutzfeldt-Jakob disease: sequential change on T2-weighted MRI
- Author
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Uemura, A., O'uchi, T., Sakamoto, T., and Yashiro, N.
- Published
- 2002
- Full Text
- View/download PDF
3. A case of bilateral reversible thalamic lesions
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Miyakawa, E., Tokumaru, A. M., O'uchi, T., Miyakawa, K., Hirata, T., Odani, Y., Ogata, H., and Nagashima, T.
- Published
- 1997
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- View/download PDF
4. Diagnosis of peanut inhalation by MRI
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Kitanaka, S., Mikami, I., Tokumaru, A., and O'Uchi, T.
- Published
- 1992
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- View/download PDF
5. Characteristics of Intravascular Large B-Cell Lymphoma on Cerebral MR Imaging
- Author
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Yamamoto, A., primary, Kikuchi, Y., additional, Homma, K., additional, O'uchi, T., additional, and Furui, S., additional
- Published
- 2011
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- View/download PDF
6. MR findings of granulocytic sarcoma of the breasts
- Author
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Nishida, H, primary, Kinoshita, T, additional, Yashiro, N, additional, Ikeda, Y, additional, and O'Uchi, T, additional
- Published
- 2006
- Full Text
- View/download PDF
7. Application of Diffusion-Weighted EPI to Cerebrovascular Disease
- Author
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O'Uchi, T., primary, Kuru, Y., additional, Honda, S., additional, Hayashi, T., additional, and Yasuda, R., additional
- Published
- 1998
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- View/download PDF
8. Cross sectional observation of the effects of carbon disulphide on arteriosclerosis in rayon manufacturing workers
- Author
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Omae, K., primary, Takebayashi, T., additional, Nomiyama, T., additional, Ishizuka, C., additional, Nakashima, H., additional, Uemura, T., additional, Tanaka, S., additional, Yamauchi, T., additional, O'Uchi, T., additional, Horichi, Y., additional, and Sakurai, H., additional
- Published
- 1998
- Full Text
- View/download PDF
9. Intracranial aneurysms: diagnostic accuracy of MR angiography with evaluation of maximum intensity projection and source images.
- Author
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Korogi, Y, primary, Takahashi, M, additional, Mabuchi, N, additional, Nakagawa, T, additional, Fujiwara, S, additional, Horikawa, Y, additional, Miki, H, additional, O'Uchi, T, additional, Shiga, H, additional, Shiokawa, Y, additional, Watabe, T, additional, and Furuse, M, additional
- Published
- 1996
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- View/download PDF
10. Intracranial aneurysms: diagnostic accuracy of three-dimensional, Fourier transform, time-of-flight MR angiography.
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Korogi, Y, primary, Takahashi, M, additional, Mabuchi, N, additional, Miki, H, additional, Fujiwara, S, additional, Horikawa, Y, additional, Nakagawa, T, additional, O'Uchi, T, additional, Watabe, T, additional, and Shiga, H, additional
- Published
- 1994
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11. Intracranial vascular stenosis and occlusion: diagnostic accuracy of three-dimensional, Fourier transform, time-of-flight MR angiography.
- Author
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Korogi, Y, primary, Takahashi, M, additional, Mabuchi, N, additional, Miki, H, additional, Shiga, H, additional, Watabe, T, additional, O'Uchi, T, additional, Nakagawa, T, additional, Horikawa, Y, additional, and Fujiwara, S, additional
- Published
- 1994
- Full Text
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12. Ischemic Brain Lesions in Aged Patients With Dizziness
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Yamasoba, T., primary, Kikuchi, S., additional, Higo, R., additional, Kaga, K., additional, O'uchi, T., additional, and Tokumaru, A., additional
- Published
- 1993
- Full Text
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13. Value of MR imaging in detecting a peanut causing bronchial obstruction.
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O'Uchi, T, primary, Tokumaru, A, additional, Mikami, I, additional, Yamasoba, T, additional, and Kikuchi, S, additional
- Published
- 1992
- Full Text
- View/download PDF
14. Brain magnetic resonance findings in infective endocarditis with neurological complications.
- Author
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Azuma A, Toyoda K, O'uchi T, Azuma, Asako, Toyoda, Keiko, and O'uchi, Toshihiro
- Abstract
Purpose: Diagnosing infective endocarditis and its complications can be difficult because of the nonspecific symptoms. We reviewed findings of intracranial abnormalities on magnetic resonance imaging (MRI) in 14 patients with neurological complications and herein discuss the overall intracranial MRI findings.Materials and Methods: We retrospectively reviewed patients with infective endocarditis from August 2004 to August 2006. Brain MRI, the causative bacteria, and abnormal neurological symptoms were reviewed for 14 patients with neurological complications.Results: Of the 14 patients, 13 showed intracranial abnormalities on MRI. Embolization was seen in 10 patients, hemorrhage in 3, abscess formation in 3, and encephalitis in 2. Hyperintense lesions with a central hypointense area on T2-weighted and/or T2*-weighted imaging (Bull's-eye-like lesion) were seen in four patients. A combination of these intracranial abnormalities was observed in 6 patients.Conclusion: The MRI findings associated with infective endocarditis are wide-ranging: embolization, hemorrhage, meningitis, cerebritis, abscess, the bull's-eye-like lesion. Clinicians should consider the possibility of infective endocarditis in patients with unknown fever and neurological abnormality. Brain MRI should be promptly performed for those patients, and T2*-weighted imaging is recommended for an early diagnosis of infective endocarditis. [ABSTRACT FROM AUTHOR]- Published
- 2009
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15. Assessment of brain death in children by means of P-31 MR spectroscopy: preliminary note. Work in progress.
- Author
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Kato, T, primary, Tokumaru, A, additional, O'uchi, T, additional, Mikami, I, additional, Umeda, M, additional, Nose, K, additional, Eguchi, T, additional, Hasegawa, M, additional, and Okuyama, K, additional
- Published
- 1991
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16. Monitoring of early response to neoadjuvant chemotherapy in breast cancer with (1)H MR spectroscopy: comparison to sequential 2-[18F]-fluorodeoxyglucose positron emission tomography.
- Author
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Tozaki M, Sakamoto M, Oyama Y, O'uchi T, Kawano N, Suzuki T, Yamashiro N, Ozaki S, Sakamoto N, Higa K, Abe S, Ogawa T, and Fukuma E
- Published
- 2008
- Full Text
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17. Prominent meningeal enhancement adjacent to meningioma on Gd-DTPA-enhanced MR images: histopathologic correlation.
- Author
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Tokumaru, A, primary, O'uchi, T, additional, Eguchi, T, additional, Kawamoto, S, additional, Kokubo, T, additional, Suzuki, M, additional, and Kameda, T, additional
- Published
- 1990
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18. MR Angiography of Intracranial Aneurysms: A Comparison of 0.5 T and 1.5 T
- Author
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Korogi, Y., Takahashi, M., Mabuchi, N., Watabe, T., Shiokawa, Y., Shiga, H., O'Uchi, T., Nakagawa, T., Miki, H., and Horikawa, Y.
- Published
- 1997
- Full Text
- View/download PDF
19. Brain and magnetic resonance imaging
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O'uchi, T., primary
- Published
- 1986
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20. Application of Diffusion-Weighted EPI to Cerebrovascular Disease
- Author
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O'Uchi, T., Kuru, Y., Honda, S., Hayashi, T., and Yasuda, R.
- Abstract
Diffusion-weighted EPI using Siemens Vision was applied in 276 cases with cerebral vascular disease. Acute cerebral infarction up to 22 days after the onset showed high signal on DW-EPI. DW-EPI with 20 second acquisition time is superior to CT scan and T2WI in cases of acute cerebral infarction. Intracranial hematoma showed a homogeneous high signal within one day after the onset. Marginal low signal of the hematoma afterwards. Cytotoxic edema around the hematoma was recognized in two cases out of 25.
- Published
- 1998
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21. Intracranial Vascular Stenosis and Occlusion.
- Author
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Korogi, Y, Takahashi, M, Nakagawa, T, Mabuchi, N, Watabe, T, Shiokawa, Y, Shiga, H, O'Uchi, T, Miki, H, Horikawa, Y, Fujiwara, S, and Furuse, M
- Published
- 1999
22. Preoperative CT Findings for Predicting Acute Exacerbation of Interstitial Pneumonia After Lung Cancer Surgery: A Multicenter Case-Control Study.
- Author
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Ozawa Y, Shibamoto Y, Hiroshima M, Nakagawa M, Ono A, Hanaoka R, Yamamoto A, Tominaga J, Kawada H, Koyama M, Takumi K, Tsubakimoto M, Egashira R, Tsushima F, Kikuchi Y, Izumi Y, Ushio T, Kimura M, Ichikawa S, Kitamura N, Matsushita S, Okauchi K, O'uchi T, Ishikawa H, and Kitase M
- Subjects
- Adult, Aged, Aged, 80 and over, Case-Control Studies, Disease Progression, Female, Humans, Logistic Models, Lung Diseases, Interstitial complications, Lung Diseases, Interstitial pathology, Lung Neoplasms complications, Lung Neoplasms pathology, Male, Middle Aged, Pneumonectomy adverse effects, Postoperative Complications diagnostic imaging, Postoperative Complications pathology, Preoperative Period, Pulmonary Artery diagnostic imaging, Pulmonary Artery pathology, Retrospective Studies, Risk Factors, Lung Diseases, Interstitial diagnostic imaging, Lung Neoplasms surgery, Tomography, X-Ray Computed
- Abstract
BACKGROUND. Acute exacerbation (AE) is a life-threatening complication of inter-stitial pneumonia (IP). Thoracic surgery may trigger AE. OBJECTIVE. The purpose of this study is to explore the role of preoperative CT findings in predicting postoperative AE in patients with IP and lung cancer. METHODS. This retrospective case-control study included patients from 22 institutions who had IP and underwent thoracic surgery for lung cancer. AE was diagnosed on the basis of symptoms and imaging findings noted within 30 days after surgery and the absence of alternate causes. For each patient with AE, two control patients without AE were identified. After exclusions, the study included 92 patients (78 men and 14 women; 31 with AE [the AE group] and 61 without AE [the no-AE group]; mean age, 72 years). Two radiologists independently reviewed preoperative thin-slice CT examinations for pulmonary findings and resolved differences by consensus. The AE and no-AE groups were compared using the Fisher exact and Mann-Whitney U tests. Multivariable logistic regression was performed. Interreader agreement was assessed by kappa coefficients. RESULTS. A total of 94% of patients in the AE group underwent segmentectomy or other surgery that was more extensive than wedge resection versus 75% in the no-AE group ( p = .046). The usual IP pattern was present in 58% of the AE group versus 74% of the no-AE group ( p = .16). According to subjective visual scoring, the mean (± SD) ground-glass opacity (GGO) extent was 6.3 ± 5.4 in the AE group versus 3.9 ± 3.8 in the no-AE group ( p = .03), and the mean consolidation extent was 0.5 ± 1.2 in the AE group versus 0.1 ± 0.3 in the no-AE group ( p = .009). Mean pulmonary trunk diameter was 28 ± 4 mm in the AE group versus 26 ± 3 mm in the no-AE group ( p = .02). In a model of CT features only, independent predictors of AE ( p < .05) were GGO extent (odds ratio [OR], 2.8), consolidation extent (OR, 9.4), and pulmonary trunk diameter (OR, 4.2); this model achieved an AUC of 0.75, a PPV of 71%, and an NPV of 77% for AE. When CT and clinical variables were combined, undergoing segmentectomy or more extensive surgery also independently predicted AE (OR, 8.2; p = .02). CONCLUSION. The presence of GGO, consolidation, and pulmonary trunk enlargement on preoperative CT predicts AE in patients with IP who are undergoing lung cancer surgery. CLINICAL IMPACT. Patients with IP and lung cancer should be carefully managed when predictive CT features are present. Wedge resection, if possible, may help reduce the risk of AE in these patients. TRIAL REGISTRATION. University Hospital Medical Information Clinical Trial Registry UMIN000029661.
- Published
- 2021
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23. Positron Emission Tomography in T3/T4 Non-Small Cell Lung Cancer After Induction Chemoradiotherapy.
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Nomori H, Shiraishi A, O'uchi T, Honma K, Shoji K, Misawa M, Sugimura H, and Oyama Y
- Subjects
- Adult, Aged, Aged, 80 and over, Carcinoma, Non-Small-Cell Lung pathology, Disease-Free Survival, Female, Fluorodeoxyglucose F18, Humans, Lung Neoplasms pathology, Male, Middle Aged, Neoplasm Staging, Radiopharmaceuticals, Retrospective Studies, Carcinoma, Non-Small-Cell Lung diagnostic imaging, Carcinoma, Non-Small-Cell Lung therapy, Chemoradiotherapy, Lung Neoplasms diagnostic imaging, Lung Neoplasms therapy, Positron-Emission Tomography methods
- Abstract
Background: To predict pathological response and survival in T3/T4 non-small cell lung cancer after induction chemoradiotherapy by assessing fluorodeoxyglucose uptake with positron emission tomography., Methods: In this retrospective observational study, standard uptake values of whole tumors and extrapulmonary involvement sites were measured after induction chemoradiotherapy. The values were then compared with pathological responses and recurrence-free survival., Results: Fifty-seven patients with clinical T3/T4 tumors were treated by chemoradiotherapy followed by surgery. Pathological complete response was observed in 33% of patients (19 of 57). With the cutoff value of 3.3 for whole tumor fluorodeoxyglucose uptake for estimating complete response, 38% patients (9 of 24) with values lower than the cutoff value were false-negative. Tumor remission at extrapulmonary involvement sites was observed in 82% patients (47 of 57), and the cutoff value of the extrapulmonary uptake was 3.0 without any false negatives. Recurrence-free survival was significantly better in patients with values lower than both the whole- and extrapulmonary-uptake cutoff values than in patients with higher values (P = .016 and P = .001, log-rank test, respectively). Among 7 patients who avoided en bloc resections of involved structures because of lowered extrapulmonary uptakes and negative findings in intraoperative frozen sections, none experienced margin recurrence., Conclusions: Even when whole tumor uptakes in patients with T3/T4 tumors markedly decrease after induction chemoradiotherapy, surgical treatment is still indicated because of possible residual tumors. Tumor remission at extrapulmonary involvement sites could be predicted by extrapulmonary uptake values. Both whole- and extrapulmonary-uptake values after induction chemoradiotherapy could be used to predict prognosis., (Copyright © 2020 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.)
- Published
- 2020
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24. Medullary Abnormalities in Appendicular Skeletons Detected With 18 F-FDG PET/CT Predict an Unfavorable Prognosis in Newly Diagnosed Multiple Myeloma Patients With High-Risk Factors.
- Author
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Abe Y, Narita K, Kobayashi H, Kitadate A, Takeuchi M, O'uchi T, and Matsue K
- Subjects
- Aged, Aged, 80 and over, Female, Fluorodeoxyglucose F18, Humans, Male, Prognosis, Radiopharmaceuticals, Retrospective Studies, Risk Factors, Survival Rate, Bone Neoplasms diagnostic imaging, Multiple Myeloma diagnostic imaging, Positron Emission Tomography Computed Tomography
- Abstract
OBJECTIVE. The prognostic value of medullary abnormalities in the appendicular skeleton (AS) of patients with multiple myeloma (MM) has recently been suggested. However, functional evaluation of these abnormalities using PET/CT has not been investigated to date. This study aimed to explore the prevalence and prognostic relevance of AS medullary abnormalities depicted by PET/CT in patients with MM. MATERIALS AND METHODS. This retrospective study included 228 consecutive patients with newly diagnosed, symptomatic MM who were treated with novel agents. All patients underwent pretreatment
18 F-FDG PET/CT. RESULTS. There were 157 (68.9%) patients with zero AS focal lesions, 33 (14.5%) with one to three AS focal lesions, and 38 (16.7%) with more than three AS focal lesions on pre-treatment PET/CT. Patients with more than three AS focal lesions showed significantly shorter progression-free survival (PFS) and overall survival (OS) than did those with fewer lesions (both, p < 0.001). In multivariate analysis, the presence of more than three AS focal lesions remained prognostic for both PFS and OS (both, p < 0.001). Furthermore, the presence of more than three AS focal lesions discriminated patients with both significantly shorter PFS and significantly shorter OS even among patients with established high-risk parameters, including high-risk cytogenetic abnormalities, advanced disease stage, and established high-risk PET/CT findings. CONCLUSION. The presence of more than three focal lesions in the AS on pretreatment PET/CT was an independent predictor of poor survival in patients with newly diagnosed MM. Remarkably, this finding discriminated patients with shorter survival from among those with established high-risk factors. Evaluation of findings in the AS may complement and improve the prognostic performance of known stratification systems as well as PET/CT.- Published
- 2019
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25. Pretreatment 18 F-FDG PET/CT combined with quantification of clonal circulating plasma cells as a potential risk model in patients with newly diagnosed multiple myeloma.
- Author
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Abe Y, Narita K, Kobayashi H, Kitadate A, Miura D, Takeuchi M, O'uchi E, O'uchi T, and Matsue K
- Subjects
- Aged, Aged, 80 and over, Female, Humans, Male, Middle Aged, Multivariate Analysis, Neoplasm Staging methods, Prognosis, Radiopharmaceuticals, Retrospective Studies, Risk Assessment, Risk Factors, Whole Body Imaging, Fluorodeoxyglucose F18 analysis, Multiple Myeloma diagnostic imaging, Plasma Cells cytology, Positron Emission Tomography Computed Tomography
- Abstract
Purpose: Both
18 F-FDG PET/CT and clonal circulating plasma cell (CPC) quantification are emerging tools for multiple myeloma (MM) prognostication that have been validated in recent studies. This study investigated the value of PET/CT coupled with CPC quantification for MM prognostication that may contribute to future risk-adapted treatment., Methods: We retrospectively analysed the prognostic relevance of a combination of pretreatment PET/CT findings and CPC levels in 163 consecutive patients with newly diagnosed, symptomatic MM receiving novel agents during induction therapies., Results: High-risk PET/CT findings and elevated CPC levels were defined by the presence of >3 focal lesions with or without extramedullary disease and CPCs ≥0.10% of the total mononuclear cells evaluated, respectively. Subsequently, patients were divided into three groups: PET-CPC stage I included patients with no high-risk PET/CT findings and low CPC levels; stage III included patients with high-risk PET/CT findings and high CPC levels; and stage II included the remaining patients. The three groups of patients differed significantly in terms of both progression-free survival (PFS) and overall survival (OS) (median PFS: not reached [NR] and 36.4 and 15.9 months, and median OS: NR, NR, and 40.4 months for stages I, II, and III, respectively; P < 0.001 for both PFS and OS). This system discriminated both PFS and OS even among younger (age < 75 years) or older (≥ 75 years) patients, patients with Revised International Staging System stage II or III, and patients with or without high-risk cytogenetic characteristics. In the multivariate analysis, the PET-CPC staging system remained prognostic for both PFS and OS., Conclusions: The PET-CPC staging system predicted survival outcomes independently of established risk factors in patients with newly diagnosed MM. Pretreatment18 F-FDG PET/CT assessment combined with CPC quantification may improve the prognostication of MM and facilitate the development of novel risk-adapted approaches for MM.- Published
- 2019
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26. Low hexokinase-2 expression-associated false-negative 18 F-FDG PET/CT as a potential prognostic predictor in patients with multiple myeloma.
- Author
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Abe Y, Ikeda S, Kitadate A, Narita K, Kobayashi H, Miura D, Takeuchi M, O'uchi E, O'uchi T, and Matsue K
- Subjects
- Aged, Aged, 80 and over, False Negative Reactions, Female, Humans, Male, Middle Aged, Multiple Myeloma enzymology, Prognosis, Radiopharmaceuticals, Retrospective Studies, Treatment Outcome, Diffusion Magnetic Resonance Imaging, Fluorodeoxyglucose F18 analysis, Hexokinase metabolism, Multiple Myeloma diagnostic imaging, Positron Emission Tomography Computed Tomography
- Abstract
Purpose: False-negative
18 F-FDG PET/CT, which is associated with low hexokinase-2 (HK2) expression in multiple myeloma (MM), is a new concept that is relevant for diagnosis and treatment response assessment. This study aimed to investigate the prognostic relevance of low HK2 expression-associated false-negative PET/CT in patients with MM., Methods: Ninety consecutive patients, with newly diagnosed MM, receiving novel agents during induction therapy were enrolled in this retrospective study. Patients were divided into three groups according to the combination of the positivity of PET/CT and whole-body diffusion-weighted magnetic resonance imaging (DWMRI), namely, negative DWMRI, false-negative PET/CT, and positive PET/CT., Results: False-negative PET/CT was observed in 12% patients who were older, had documented clinical history of smouldering MM, and showed lower HK2 expression levels than the positive PET/CT patients. False-negative PET/CT patients showed a clear trend of longer time to next treatment (TTNT) and progression-free survival (PFS) than the positive PET/CT patients (P = 0.035 and 0.071, respectively). Furthermore, TTNT and PFS of false-negative PET/CT patients were similar to those of patients without established high-risk PET/CT findings and significantly longer than those of high-risk PET/CT patients (P = 0.013 and 0.047, respectively)., Conclusions: This study showed, for the first time, that low HK2 expression-associated false-negative PET/CT was associated with relatively better prognosis in patients with newly diagnosed MM, suggesting that this phenomenon may not undermine the established PET/CT-based prognostication. Furthermore, this phenomenon may be useful for identifying patients at lower risk of disease progression among those with myelomatous lesions on DWMRI.- Published
- 2019
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27. Arterial inflammation measured by 18 F-FDG-PET-CT to predict coronary events in older subjects.
- Author
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Iwatsuka R, Matsue Y, Yonetsu T, O'uchi T, Matsumura A, Hashimoto Y, and Hirao K
- Subjects
- Age Factors, Aged, Aged, 80 and over, Aging, Aortitis complications, Coronary Artery Disease diagnostic imaging, Female, Humans, Male, Predictive Value of Tests, Prognosis, Retrospective Studies, Risk Assessment, Risk Factors, Time Factors, Aortitis diagnostic imaging, Coronary Artery Disease etiology, Fluorodeoxyglucose F18 administration & dosage, Positron Emission Tomography Computed Tomography, Radiopharmaceuticals administration & dosage
- Abstract
Background and Aims: Although
18 F-fluorodeoxyglucose (FDG) uptake has emerged as a sensitive and reliable marker of atherosclerotic inflammation, its additive predictive value for future coronary disease in older subjects is unknown. The aim of this study was to test the prognostic value of aortic inflammation detected via FDG-positron emission tomography (PET)-computed tomography (CT) in older subjects., Methods: We retrospectively utilized the records of 309 subjects aged over 65 years, without a history of coronary artery disease, who underwent18 F-FDG-PET-CT mostly due to the clinical suspicion of cancer, but eventually turned out to be cancer-free. Target-to-background ratio (TBR) was calculated at the ascending aorta. The endpoint was occurrence of coronary heart disease (CHD) events., Results: During a median follow-up of 3.9 years, 28 subjects experienced CHD events and 12 patients died due to non-CHD causes. The highest TBR tertile was associated with a high CHD event rate, accounting for death due to non-CHD causes as a competing risk (Gray test, p = 0.005). In a Fine and Gray competing risk proportional hazard regression model, TBR was associated with significantly high CHD events independently of FRS, with a hazard ratio (HR) of 1.19 per 0.1 TBR increase (p < 0.001). Likewise, a significant increase in the area under the curve (from 0.57 to 0.73, p = 0.028) and a significant improvement in net reclassification (0.42, p = 0.038) were observed when TBR was added to the model with FRS alone., Conclusions: In older subjects with no history of malignant disease or overt coronary artery disease, arterial inflammation evaluated by FDG uptake provides information on future occurrence of coronary artery events., (Copyright © 2017 Elsevier B.V. All rights reserved.)- Published
- 2018
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28. Imaging characteristics of the postoperative globe: a pictorial essay.
- Author
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Ito Y, Yamazaki I, Kikuchi Y, O'uchi E, O'uchi T, Kato H, and Hotta K
- Subjects
- Balloon Occlusion, Cataract Extraction, Glaucoma surgery, Humans, Retinal Detachment, Scleral Buckling, Eye diagnostic imaging, Magnetic Resonance Imaging methods, Ophthalmologic Surgical Procedures methods, Postoperative Care methods, Tomography, X-Ray Computed methods
- Abstract
Recognizing imaging characteristics after ophthalmic surgery is necessary for radiologists to prevent misdiagnosis. We review typical appearances of intraorbital implanted devices and materials on CT and MRI with demonstration of the common surgical procedures. EX-PRESS glaucoma filtration devices appear as punctate areas of metal attenuation on CT and are typically placed at the corneoscleral junction. The imaging manifestations after cataract extraction are absence of the native lens of ovoid mass and the intraocular lens with high attenuation on CT and low signal intensity on MRI. The treatment of retinal detachment is achieved with intraocular tamponade or scleral buckling. In intraocular tamponade, the eye is filled with a bubble of gas or silicone oil. Gas results in air attenuation on CT and low signal intensity on MRI in the vitreous cavity. Silicone oil is hyperattenuating on CT and has variable intensity on MRI. In scleral buckling, the eye wall is indented with silicone buckling elements that show high or low attenuation on CT and low T1- and T2-weighted intensity on MRI. Degraded hydrogel buckling elements appear as swollen masses showing low attenuation on CT and high T2-weighted intensity on MRI.
- Published
- 2016
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29. Fenestrations of the basilar artery demonstrated on magnetic resonance angiograms: an analysis of 212 cases.
- Author
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Sogawa K, Kikuchi Y, O'uchi T, Tanaka M, and Inoue T
- Subjects
- Comorbidity, Female, Humans, Japan epidemiology, Male, Middle Aged, Prevalence, Radiography, Reproducibility of Results, Risk Factors, Sensitivity and Specificity, Basilar Artery abnormalities, Basilar Artery diagnostic imaging, Intracranial Aneurysm diagnostic imaging, Intracranial Aneurysm epidemiology, Intracranial Arteriovenous Malformations diagnostic imaging, Intracranial Arteriovenous Malformations epidemiology, Magnetic Resonance Angiography statistics & numerical data
- Abstract
Fenestration of the basilar artery (BA) is a rare variant of the intracranial artery, well demonstrated in autopsy and angiographic studies. Some angiographic series show a high incidence of associated aneurysms at the basilar fenestration site. The purpose of this study is to report the incidence of BA fenestration, its configurations, associated aneurysms, and arterial anomalies in a large series of intracranial MR angiograms (MRAs). A total of 16,416 MRAs were retrospectively reviewed to identify the location, size and associated intracranial arterial anomalies of BA fenestrations. All images were obtained with the time-of-flight (TOF) technique. Of the 16,416 MRAs, 215 fenestrations were found in 212 cases (1.29%). Most fenestrations were located in the proximal BA. The average length of the fenestration was 4.6 mm; the largest was 15.6 mm. No aneurysm was found at the site of the fenestration. Thirteen aneurysms were found in nine cases at locations other than the BA: seven in the middle cerebral artery (MCA), one in the anterior cerebral artery (ACA), one in the anterior communicating artery (Acom), one in the vertebral artery (VA), one at the carotid siphon, and two at the internal carotid-posterior communicating artery (IC-PC). Arterial anomalies in other locations were found in 26 cases. BA fenestrations were found in 1.29% of the 16,416 cases studied. There were no aneurysms at the BA fenestration site. Aneurysms at the BA fenestration site may be an exceedingly rare phenomenon.
- Published
- 2013
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30. Is emphysema a risk factor for pneumothorax in CT-guided lung biopsy?
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Asai N, Kawamura Y, Yamazaki I, Sogawa K, Ohkuni Y, O'uchi T, Kubo A, Yamaguchi E, and Kaneko N
- Abstract
Introduction: Computed tomography (CT)-guided lung biopsy is commonly used to make a histological diagnosis for pulmonary lesions. Its most common complication is pneumothorax. While it is thought that CT-guided lung biopsy should be avoided in patients with emphysema, however, there is no scientific report documenting the relationship the occurrence of pneumothorax and the severity of emphysema., Purpose and Methods: To investigate the relationship between the severity of emphysema and the frequency of pneumothorax, we retrospectively reviewed all the patients who received CT-guided lung biopsy. Severity of emphysema is evaluated by Goddard classification, a visual scale by which areas of vascular disruption and low attenuation value were scored for each lung field of high resolution CT. Patients' characteristics, prognostic accuracy of this method, size and location of the lesion, length of intrapulmonary biopsy paths, and frequency of complications such as pneumothorax or intrapulmonary hemorrhage were evaluated., Results: One hundred-two patients (69 males and 33 females) received 102 procedures. Diagnostic accuracy was 90.2%. Pneumothorax occurred in 41 of 102 biopsies (40.2%). Chest tube placement was required in 3 out of the 41 cases (7.3%) complicated by pneumothorax (2.9% of all the biopsies). The longer lesion depths from pleura were, the more frequently pneumothorax occurred (6.67 vs 3.66 mm, p=0.019). No correlation was found between location of lesions and frequency of pneumothorax. No significant differences of COPD staging or LAA score were seen between the patients with and without pneumothorax (5.73 vs 4.32 points, p=0.339)., Conclusion: We suggest that severity of emphysema such as stage I or II COPD may not be related to the frequency of pneumothorax.
- Published
- 2013
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31. A case of Proteus syndrome with severe spinal canal stenosis, scoliosis, and thoracic deformity associated with tethered cord.
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Yamamoto A, Kikuchi Y, Yuzurihara M, Kubota M, and O'uchi T
- Subjects
- Child, Diagnosis, Differential, Fatal Outcome, Humans, Magnetic Resonance Imaging, Male, Radiography, Thoracic, Tomography, X-Ray Computed, Proteus Syndrome diagnosis, Scoliosis diagnosis, Spinal Stenosis diagnosis, Thoracic Vertebrae abnormalities
- Abstract
Proteus syndrome is a rare, sporadic, hamartomatous disorder manifesting with multifocal overgrowth of tissue. The features seem to develop most often during childhood. Vertebral overgrowth with severe spinal canal stenosis is unusual, although scoliosis with abnormal vertebral bodies is one of the typical features of Proteus syndrome. We report a case of Proteus syndrome with severe spinal canal stenosis, scoliosis, cervical kyphosis, and thoracic deformity with airway obstruction because of asymmetrical overgrowth of vertebrae and ribs associated with a tethered cord, lipomas, strawberry hemangioma, flat nasal bridge, and bilateral hypoplasty of the first metatarsal bones with hyperplasty of soft tissue.
- Published
- 2012
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32. Characteristics of intravascular large B-cell lymphoma on cerebral MR imaging.
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Yamamoto A, Kikuchi Y, Homma K, O'uchi T, and Furui S
- Subjects
- Aged, Aged, 80 and over, Female, Humans, Male, Middle Aged, Retrospective Studies, Brain pathology, Lymphoma, Large B-Cell, Diffuse pathology, Magnetic Resonance Imaging, Neuroimaging, Vascular Neoplasms pathology
- Abstract
IVL is characterized by a propensity for intravascular tumor cell proliferation. Premortem diagnosis of IVL is difficult because of its nonspecific clinical, laboratory, and imaging manifestations. This study examined cerebral MR imaging patterns of IVL and their changes with and without chemotherapy. Nine of 11 patients studied presented with abnormal findings. We define 5 patterns of abnormal MR imaging findings: 1) infarctlike lesions, 2) nonspecific white matter lesions, 3) meningeal enhancement, 4) masslike lesions, and 5) hyperintense lesions in the pons on T2WI. Seven patients presented with only 1 pattern, while 2 patients presented with multiple patterns. Lesions in 7 treated patients responded to chemotherapy. Pathologic specimens revealed intravascular tumor cell infiltration with associated infarctions, necrosis, congestion, demyelination, vasculitis, and tumor cell extravasation. We conclude that MR imaging patterns can be possible manifestations of intravascular-dominant infiltration by tumor cells with associated occlusion or inflammation, depending on the level of affected vessels.
- Published
- 2012
- Full Text
- View/download PDF
33. High frequency of neurolymphomatosis as a relapse disease of intravascular large B-cell lymphoma.
- Author
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Matsue K, Hayama BY, Iwama K, Koyama T, Fujiwara H, Yamakura M, Takeuchi M, and O'uchi T
- Subjects
- Aged, Aged, 80 and over, Animals, Cranial Nerves pathology, Female, Humans, Lymphoma, Large B-Cell, Diffuse drug therapy, Lymphoma, Large B-Cell, Diffuse pathology, Magnetic Resonance Imaging, Male, Marek Disease drug therapy, Marek Disease pathology, Medical Records, Neoplasm Staging, Positron-Emission Tomography, Prognosis, Survival Rate, Tomography, X-Ray Computed, Vascular Neoplasms drug therapy, Vascular Neoplasms pathology, Lymphoma, Large B-Cell, Diffuse complications, Marek Disease etiology, Peripheral Nerves pathology, Vascular Neoplasms complications
- Abstract
Background: Intravascular large B-cell lymphoma (IVL) is characterized by lymphoma cell proliferation in the lumina of small vessels in various organs. A high incidence of neurologic symptoms associated with the central nervous system has been reported, but peripheral nerve involvement (neurolymphomatosis [NL]) rarely has been described., Methods: The medical records from patients who were diagnosed with IVL over the past 4 years were reviewed. A diagnosis of NL was made based on the combination of neurologic symptoms and their correspondence with imaging studies, such as magnetic resonance imaging (MRI), (18) F-fluoro-2-deoxy-D-glucose (FDG)-positron emission tomography/computed tomography (PET/CT), and/or the histologic confirmation of lymphoma cells within the peripheral nerves, nerve root/plexuses, or cranial nerves., Results: Four patients with NL were identified among 11 patients who had IVL. All cases of NL occurred as relapsed disease during or shortly after the completion of chemotherapy. Although MRI studies of the brains and whole spines revealed nerve infiltration by gadolinium enhancement in 2 patients, the technology was not sensitive enough to detect such infiltration in the remaining 2 patients. In contrast, FDG-PET/CT studies successfully revealed cranial or peripheral nerve lesions in all 4 patients and was useful for evaluating therapeutic response. Patients received treatment with high-dose methotrexate with or without other systemic chemotherapy, which achieved varied success. Further studies will be needed to determine the optimal treatment., Conclusions: Considering the rarity of IVL and NL, the current observations suggested that IVL may have a predilection not only for the vessels but also for both the central and peripheral nervous systems., (Copyright © 2011 American Cancer Society.)
- Published
- 2011
- Full Text
- View/download PDF
34. Persistent primitive trigeminal arteries (PTA) and its variant (PTAV): analysis of 103 cases detected in 16,415 cases of MRA over 3 years.
- Author
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O'uchi E and O'uchi T
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Arterio-Arterial Fistula congenital, Carotid Artery Diseases congenital, Child, Child, Preschool, Female, Humans, Infant, Japan epidemiology, Male, Middle Aged, Prevalence, Risk Assessment methods, Risk Factors, Young Adult, Arterio-Arterial Fistula diagnosis, Arterio-Arterial Fistula epidemiology, Basilar Artery abnormalities, Basilar Artery pathology, Carotid Artery Diseases diagnosis, Carotid Artery Diseases epidemiology, Magnetic Resonance Angiography statistics & numerical data
- Abstract
Introduction: The primitive persistent trigeminal artery (PTA) is the most common carotid-basilar anastomosis, but because of its extremely low incidence, it is poorly understood. The purpose of this study is to clarify the features of PTA and its variants (PTAV) based on a large magnetic resonance angiography (MRA) series., Methods: MRA was performed on continuous 16,415 patients (8,610 males and 7,805 females) between October 2005 and September 2008 using two 1.5-T systems and one 1.0-T system. These all MRAs were evaluated by neuroradiologists., Results: The incidence of both PTA and PTAV was 0.68% (48 cases of PTA, 50 cases of PTAV, and five unclassified). Among them, 65 cases originated from the left internal carotid artery and 38 from the right. There were 44 cases of lateral type PTA and four cases of medial type. Hypoplasia of the basilar artery proximal to the union of PTA was recognized as follows: no hypoplasia in 12 cases, moderate hypoplasia in 22 cases, and severe hypoplasia in 13 cases. Distance from SCA and the union was an average of 6.7 mm. Four cases of pre- and postoperative cerebral aneurysms were recognized in 103 cases (3.9%)., Conclusion: We have identified details of both PTA/PTAV. The incidence of PTA was similar to previous studies, and the co-existence of cerebral aneurysm was also similar when compared to patients in the general population without PTA or PTAV.
- Published
- 2010
- Full Text
- View/download PDF
35. Neurolymphomatosis involving the trigeminal nerve and deep peroneal nerve in a patient with relapsed intravascular large B-cell lymphoma.
- Author
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Koyama T, O'uchi T, and Matsue K
- Subjects
- Female, Humans, Magnetic Resonance Imaging, Recurrence, Tomography, X-Ray Computed, Lymphoma, Large B-Cell, Diffuse pathology, Peroneal Nerve pathology, Trigeminal Nerve pathology, Vascular Neoplasms pathology
- Published
- 2010
- Full Text
- View/download PDF
36. Ductal carcinoma in situ: correlation between FDG-PET/CT and histopathology.
- Author
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Azuma A, Tozaki M, Ito K, Fukuma E, Tanaka T, and O'uchi T
- Subjects
- Adult, Aged, Aged, 80 and over, Algorithms, Breast Neoplasms diagnostic imaging, Carcinoma, Intraductal, Noninfiltrating diagnostic imaging, Female, Humans, Middle Aged, Radiopharmaceuticals, Reproducibility of Results, Retrospective Studies, Sensitivity and Specificity, Breast Neoplasms pathology, Carcinoma, Intraductal, Noninfiltrating pathology, Fluorodeoxyglucose F18, Positron-Emission Tomography, Tomography, X-Ray Computed
- Abstract
Purpose: The aim of this study was to determine if any correlation exists between tumor cell density and fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET)/CT) for pure or predominant ductal carcinoma in situ (DCIS)., Materials and Methods: Subjects in this retrospective review comprised 11 patients who underwent FDG-PET/CT for DCIS. Pathological tumor cell density and FDG-PET/CT images were compared. A tumor background count density ratio of >1.5 was defined as the detectable range for DCIS., Results: Pathological density of disease was high in eight patients, intermediate in one, and low in two. In all eight patients with a detectable intraductal component on PET/CT, the density of disease was classified as high. In three patients undetected by PET/CT, the density of disease was classified as intermediate or low. On statistical analysis, the correlation between the density of disease and tumor background count density ratio (TBCDR) on PET/CT was significant (<0.05), whereas the nuclear grade and Van Nuys grade were not significant. In the eight patients detected by PET/CT, the discrepancy between histopathological mapping and FDG-PET/CT mapping was >20 mm in four patients and represented underestimation in four patients who showed low density of disease in the peripheral area., Conclusions: Tumor cell density of intraductal carcinoma appears strongly correlated to detection by FDG-PET/CT.
- Published
- 2008
- Full Text
- View/download PDF
37. Job strain and arteriosclerosis in three different types of arteries among male Japanese factory workers.
- Author
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Michikawa T, Nishiwaki Y, Nomiyama T, Uemura T, O'Uchi T, Sakurai H, Omae K, and Takebayashi T
- Subjects
- Adult, Aorta pathology, Aorta physiopathology, Arteriosclerosis epidemiology, Carotid Arteries pathology, Carotid Arteries physiopathology, Cerebral Arteries diagnostic imaging, Cerebral Arteries pathology, Cross-Sectional Studies, Humans, Incidence, Internal-External Control, Japan epidemiology, Magnetic Resonance Imaging, Male, Middle Aged, Prevalence, Risk Factors, Surveys and Questionnaires, Ultrasonography, Arteriosclerosis etiology, Stress, Psychological complications, Workload psychology
- Abstract
Objectives: This study evaluated the association between job strain and subclinical indicators of arteriosclerosis simultaneously in the cerebral artery, the aorta, and the carotid artery., Methods: The participants in this cross-sectional study consisted of 352 male factory workers between the ages of 24.9 to 55.8 (mean 41.7) years who had not been exposed to any hazardous chemicals in Japan. Job strain was measured using a Japanese version of the Job Content Questionnaire developed by Karasek. The following subclinical indicators of arteriosclerosis were examined by noninvasive procedures: hyperintense spots in T2-weighted images in brain magnetic resonance imaging (MRI), pulse wave velocity of the aorta, and the stiffness parameter of the carotid artery using ultrasound and systolic and diastolic blood pressure., Results: After control for potential confounders, high job strain was associated with an increased prevalence of hyperintense spots (adjusted odds ratio 2.53, 95% confidence interval 1.14-5.63), and elevated pulse-wave velocity (adjusted increase in percent 3.5, 95% confidence interval 0.0-6.9). The stiffness parameter tended to be elevated in the high job-strain group although this trend was not statistically significant. Job strain showed no relation to blood pressure., Conclusions: In this study, job strain was associated with subclinical indicators of arteriosclerosis in different arteries although the association was not statistically significant for the carotid artery. New information is offered by brain MRI for arteriosclerosis in the cerebral artery. An increase in hyperintense spots may explain the link between job strain and cerebrovascular disease.
- Published
- 2008
- Full Text
- View/download PDF
38. Diagnosis of ectopic pregnancy with MRI: efficacy of T2*-weighted imaging.
- Author
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Yoshigi J, Yashiro N, Kinoshita T, O'uchi T, and Kitagaki H
- Subjects
- Adolescent, Adult, Diagnosis, Differential, Female, Humans, Pregnancy, Sensitivity and Specificity, Magnetic Resonance Imaging methods, Pregnancy, Ectopic diagnosis
- Abstract
Purpose: To assess MRI in diagnosing ectopic pregnancy (EP), emphasizing T(2)*-weighted imaging (WI) efficacy., Methods and Materials: This is a prospective study of 24 female patients (16 to 41 years, average 29.9) clinically suspected of EP from April 1999 to June 2001. Eighteen had minimal vaginal bleeding and slight abdominal pain. All had positive pregnancy tests, and sonography showed no intrauterine pregnancy despite estimated gestational age of embryos and/or high concentrations of human chorionic gonadotrophin. MRI was performed with a 1.5T imager (Siemens, Vision VB33A) with a body-array coil. T(2)-WI (HASTE), T(1)-WI (2D FLASH), and T(2)*-WI (2D FLASH) were obtained without contrast. T(2)-WI was routinely obtained in 3 directions. T(2)*-WI orientation was determined based on the T(2)-WI. One of 4 radiologists with experience interpreting abdominal MR images interpreted images based on transvaginal ultrasonography (TVUS) and laboratory results. Abnormal adnexal mass with remarkable low signal area on T(2)*-WI was diagnosed as EP., Results: We diagnosed 19 cases as EP. Tubectomy in eighteen and abdominal total hysterectomy in one confirmed diagnosis. In one undergoing diagnostic laparoscopy, EP was denied. In 5 cases diagnosed negative based on the above criterion, no mass was detected in three, and no area of low signal was recognized on T(2)*-WI in the masses in two. EP was denied in four of five, and in one of the five, who underwent tubectomy, EP without bleeding was diagnosed. All EP were tubal pregnancies at final diagnosis, 19 were ampullar pregnancies and one, interstitial. Using MRI to diagnose EP, with T(2)*-WI as a key diagnostic factor, sensitivity was 95%, specificity 100%, and accuracy 96%., Conclusions: MRI using T(2)*-WI is a sensitive, specific, and accurate method to evaluate EP. T(2)*-WI is highly accurate for detecting and diagnosing EP because of its sensitivity to fresh hematoma.
- Published
- 2006
- Full Text
- View/download PDF
39. Prominent laterality of the posterior cerebral artery at three-dimensional time-of-flight MR angiography in M1-segment middle cerebral artery occlusion.
- Author
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Uemura A, O'uchi T, Kikuchi Y, Yashiro N, Ihara N, and Shoji K
- Subjects
- Adult, Aged, Aged, 80 and over, Angiography, Digital Subtraction, Collateral Circulation physiology, Female, Humans, Male, Middle Aged, Predictive Value of Tests, Retrospective Studies, Severity of Illness Index, Statistics as Topic, Functional Laterality physiology, Imaging, Three-Dimensional, Infarction, Middle Cerebral Artery diagnosis, Infarction, Middle Cerebral Artery physiopathology, Magnetic Resonance Angiography, Posterior Cerebral Artery diagnostic imaging, Posterior Cerebral Artery physiopathology
- Abstract
Background and Purpose: Three-dimensional time-of-flight MR angiography (3D TOF MRA) often discloses prominent posterior cerebral artery (PCA) laterality in the setting of M1-segment middle cerebral artery (MCA) occlusion. We sought to analyze the implications of prominent PCA laterality at 3D TOF MRA., Methods: We retrospectively reviewed 3D TOF MRA and digital subtraction angiography (DSA) findings in 25 patients (12 male, 13 female; mean age, 68.8 years [age range, 29-94 years]) with M1-segment occlusion. The observable laterality of the PCA, determined on the basis of 3D TOF MRA findings, was scored according to distal signal extent and compared with findings of collateral flow from the ipsilateral PCA via the leptomeningeal anastomosis (LMA) at DSA. Frequency of PCA laterality at 3D TOF MRA in patients and that in 56 healthy control subjects was also compared., Results: The positive predictive value of PCA laterality for the existence of collateral flow was 99.9% and the negative predictive value 30.7%. The distal extent of ipsilateral PCA signal at 3D TOF MRA positively correlated with the grade of collateral flow from the PCA via the LMA (r = 0.802; P <.01). PCA laterality was significantly less common in control subjects (P <.01)., Conclusion: Prominent PCA laterality at 3D TOF MRA in patients with M1-segment occlusion represents the existence of collateral flow from the PCA via the LMA.
- Published
- 2004
40. Usefulness of gradient-echo T2*-weighted MR imaging in evaluation of transorbital penetrating cerebral injury.
- Author
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Uemura A, O'uchi T, and Yashiro N
- Subjects
- Accidental Falls, Aged, Aged, 80 and over, Humans, Male, Head Injuries, Penetrating diagnosis, Magnetic Resonance Imaging methods, Orbit injuries
- Abstract
Transorbital penetrating cerebral injury can cause severe morbidity if not identified and treated. After the removal of the object and without the clinical information, even the chance of suspicion of penetrating cerebral injury might be missed in the first investigation. We report a case of transorbital penetrating cerebral injury caused by a metal rod and diagnosed by MRI including gradient-echo T2*-weighted imaging.
- Published
- 2001
- Full Text
- View/download PDF
41. Leiomyosarcoma presenting aneurysmal dilatation of the jejunum on CT.
- Author
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Kinoshita T, Yashiro N, Yasuda R, O'uchi T, and Narita M
- Subjects
- Aged, Diagnosis, Differential, Humans, Male, Aneurysm diagnostic imaging, Jejunal Diseases diagnostic imaging, Jejunal Neoplasms diagnostic imaging, Leiomyosarcoma diagnostic imaging, Tomography, X-Ray Computed
- Published
- 2000
- Full Text
- View/download PDF
42. The evolution of cerebral blood flow in the developing brain: evaluation with iodine-123 iodoamphetamine SPECT and correlation with MR imaging.
- Author
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Tokumaru AM, Barkovich AJ, O'uchi T, Matsuo T, and Kusano S
- Subjects
- Brain diagnostic imaging, Child, Preschool, Female, Humans, Infant, Infant, Newborn, Male, Retrospective Studies, Amphetamines, Brain growth & development, Cerebrovascular Circulation, Iodine Radioisotopes, Magnetic Resonance Imaging, Tomography, Emission-Computed, Single-Photon
- Abstract
Background and Purpose: Although it is well established that brain maturation correlates temporally with the functions the newborn or infant performs at various stages of development, the precise relationship between function and anatomic brain maturation remains unclear. The purpose of this study was to investigate the developmental changes of regional cerebral blood flow (rCBF) in infants and children using iodine-123 iodoamphetamine (123I-IMP) and single-photon emission computed tomography (SPECT). These findings were correlated with the MR imaging appearance of the brain and with known developmental changes., Methods: Twenty-one 123I-IMP SPECT examinations of 17 patients, ranging in age from neonates to 2 years, were reviewed retrospectively. All children had had transient neurologic events in the neonatal period that did not significantly affect subsequent neuropsychological development. MR studies were performed in 12 of these patients and the MR findings were correlated with the SPECT results., Results: SPECT studies showed a consistent pattern of evolving changes in 123I-IMP uptake, most likely reflecting evolution of rCBF. From the 34th postconceptional week until the end of the second month after term delivery, there was predominant uptake in the thalami, brain stem, and paleocerebellum, with relatively less cortical activity. Radionuclide uptake in both the perirolandic and occipital cortices was well seen around the 40th postconceptional week and increased rapidly thereafter, with a predominance of parietal activity. By 3 months, radionuclide uptake in the cerebellar hemispheres and parietofrontal cortices increased. Frontal and temporal activity increased by age 6 to 8 months. Uptake in the basal ganglia increased by 8 months. By the beginning of the second year, rCBF showed a similar topographic pattern to that in adults., Conclusion: The time course of the changes in 123I-IMP uptake in the developing brain as detected by SPECT is similar to that of myelination and most likely reflects an overall topologic maturational pattern of the brain.
- Published
- 1999
43. Intracranial vascular stenosis and occlusion: MR angiographic findings.
- Author
-
Korogi Y, Takahashi M, Nakagawa T, Mabuchi N, Watabe T, Shiokawa Y, Shiga H, O'Uchi T, Miki H, Horikawa Y, Fujiwara S, and Furuse M
- Subjects
- Adult, Aged, Cerebral Angiography, Cerebral Arteries pathology, Diagnosis, Differential, Female, Fourier Analysis, Humans, Male, Middle Aged, Observer Variation, Reference Values, Retrospective Studies, Brain Ischemia diagnosis, Cerebral Infarction diagnosis, Image Processing, Computer-Assisted instrumentation, Intracranial Aneurysm diagnosis, Magnetic Resonance Angiography instrumentation
- Abstract
Purpose: To investigate whether obtaining axial source images from three-dimensional Fourier transform (3DFT) time-of-flight MR angiography improves the detection of intracranial vascular stenosis and occlusion if added to maximum-intensity projection (MIP) images., Methods: The angiograms of 103 patients who had MR angiography for evaluation of possible intracranial vascular disease were reviewed retrospectively in a quantitative and nonquantitative fashion. Diameters of vessels on MR angiograms were measured quantitatively by two reviewers using a magnifying loupe and compared with the results from conventional angiograms. Degrees of stenoocclusive disease were categorized into five classes; an artery with stenosis of 50% or greater was considered to be diseased. Another five observers also reviewed the MIP images with and without source images in a blinded fashion by means of nonquantitative visual inspection., Results: In all, 23 stenoocclusive lesions of 50% or greater were available for review. In the quantitative analysis, with MIP images alone, 14 (78%) of 18 moderate and severe stenoses and four (80%) of five occlusions were identified correctly. The addition of the source images increased the sensitivity to 100% for moderate and severe stenoses and to 100% for occluded vessels. In the visual inspection study, however, no statistically significant differences were found between interpretations of MIP images alone and those of MIP images in combination with source images., Conclusion: In the quantitative study, interpretation of source images rather than MIP images reduced the tendency to overestimate stenosis seen with MR angiography and improved the sensitivity for detecting stenosis of 50% or greater. There was a discrepancy between the quantitative study and visual inspection. Experienced observers had a tendency to underestimate the degree of stenosis.
- Published
- 1997
44. Corticobasal degeneration: MR with histopathologic comparison.
- Author
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Tokumaru AM, O'uchi T, Kuru Y, Maki T, Murayama S, and Horichi Y
- Subjects
- Atrophy, Basal Ganglia Diseases diagnosis, Basal Ganglia Diseases pathology, Brain Diseases pathology, Humans, Middle Aged, Nerve Degeneration, Brain pathology, Brain Diseases diagnosis, Magnetic Resonance Imaging
- Abstract
The purpose of this study was to illustrate the MR findings of corticobasal degeneration and to compare those findings with pathologic specimens. MR findings of atrophy in the perirolandic gyri, atrophy of the basal ganglia, and T2 prolongation in the posterolateral putamen are useful evidence supporting the clinical diagnosis of corticobasal degeneration.
- Published
- 1996
45. Magnetic resonance angiographic findings in vertiginous patients with slow vertebrobasilar blood flow.
- Author
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Yamasoba T, Kikuchi S, O'Uchi T, Tokumara A, Sugimura H, and Kaga K
- Subjects
- Aged, Aged, 80 and over, Blood Flow Velocity physiology, Female, Humans, Intracranial Arteriosclerosis diagnosis, Intracranial Arteriosclerosis physiopathology, Intracranial Embolism and Thrombosis diagnosis, Intracranial Embolism and Thrombosis physiopathology, Male, Middle Aged, Vertebral Artery pathology, Vertebrobasilar Insufficiency physiopathology, Vertigo physiopathology, Magnetic Resonance Angiography, Vertebrobasilar Insufficiency diagnosis, Vertigo diagnosis
- Abstract
To investigate arterial lesions underlying slow vertebrobasilar blood flow (SBF) which appears as a high intravascular signal on proton-density images, we examined 35 vertiginous patients, 15 with SBF and 20 without, using magnetic resonance angiography. Vertebrobasilar dolichoectasia, segmental stenosis with elongation and diffuse narrowing of the vertebrobasilar arteries (VBA) were found in 4, 4 and 2 patients with SBF, respectively. In one patient with SBF, the thrombi that induced SBF seemed to have embolized to distal arteries. These abnormalities were not detected in patients without SBF, although 2 patients demonstrated aneurysm in the VBA. Because SBF is frequently associated with atherosclerotic arterial lesions, patients with SBF should be treated to prevent more severe ischemic brain disease.
- Published
- 1995
- Full Text
- View/download PDF
46. Apogeotrophic type of direction-changing positional nystagmus related to slow vertebrobasilar blood flow.
- Author
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Kikuchi S, Kaga K, Yamasoba T, O'Uchi T, and Tokumaru A
- Subjects
- Adult, Aged, Blood Flow Velocity physiology, Brain Stem blood supply, Cerebral Infarction complications, Cerebral Infarction diagnosis, Electronystagmography, Female, Humans, Male, Middle Aged, Nystagmus, Pathologic diagnosis, Orientation physiology, Reference Values, Vertebrobasilar Insufficiency diagnosis, Functional Laterality physiology, Magnetic Resonance Imaging, Nystagmus, Pathologic etiology, Vertebrobasilar Insufficiency complications, Vestibular Function Tests
- Abstract
We examined the incidence of slow blood flow (SBF) in the vertebrobasilar system by magnetic resonance imaging (MRI) in 35 patients showing direction-changing positional nystagmus (DCPN). The subjects consisted of 20 patients with apogeotrophic type (group A) and 15 with geotrophic type (group B) of DCPN. Fifty-seven age-matched subjects without vestibular symptoms were examined as a control group (group C). SBF was detected in 11 (55%), 3 (20%) and 6 (11%) patients in groups A, B and C, respectively. Lacunae of the brainstem were found in 7 (35%) patients in group A and 1 (7%) in group B. The higher incidence of SBF in group A suggested a possible relationship between SBF and apogeotrophic type of DCPN. Apogeotrophic type of DCPN associated with SBF was considered to be caused by ischemia in the posterior circulation, though it was unclear whether the vestibular labyrinth or the hindbrain was mainly involved.
- Published
- 1995
- Full Text
- View/download PDF
47. Phosphorus-31 nuclear magnetic resonance in vivo spectroscopy of human liver during hepatitis A virus infection.
- Author
-
Yamane Y, Umeda M, O'uchi T, Mitsushima T, Nakata K, and Nagataki S
- Subjects
- Acute Disease, Adenosine Triphosphate metabolism, Adult, Alanine Transaminase blood, Animals, Bilirubin blood, Female, Hepatitis A diagnosis, Humans, Liver Regeneration physiology, Magnetic Resonance Spectroscopy, Male, Phosphates metabolism, Rats, Hepatitis A metabolism, Liver metabolism, Phospholipids metabolism
- Abstract
To evaluate the changes in hepatocellular phospholipid metabolism during hepatitis virus infection, 26 patients with acute viral hepatitis A were studied by means of phosphorus-31 nuclear magnetic resonance (31P-NMR) spectroscopy. The spectroscopy of liver showed six signal components in all patients as well as in the normal volunteers. During the early phase of illness, the phosphomonoester (PME)-phosphodiester (PDE) ratios in the patients became markedly greater than the ratios in the controls (P < 0.001). Within six weeks after the onset, the PME/PDE ratios returned to the level of controls. The time course analysis indicated an inverse correlation between the PME/PDE ratio and the period of time after onset (r = 0.738, P < 0.001). The spectral changes of human liver observed in acute viral hepatitis A are similar to those in the regenerating rat liver, indicating that 31P-NMR spectroscopy allows a noninvasive study of cell turnover in human liver disease associated with acute virus infection.
- Published
- 1994
- Full Text
- View/download PDF
48. Sudden sensorineural hearing loss associated with slow blood flow of the vertebrobasilar system.
- Author
-
Yamasoba T, Kikuchi S, Higo R, O'uchi T, and Tokumaru A
- Subjects
- Adolescent, Adult, Aged, Basilar Artery physiopathology, Blood Flow Velocity, Child, Female, Hearing Loss, Sudden physiopathology, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Vertebral Artery physiopathology, Vertebrobasilar Insufficiency diagnosis, Vertigo etiology, Hearing Loss, Sudden etiology, Vertebrobasilar Insufficiency complications
- Abstract
To determine the characteristics of sudden deafness associated with slow blood flow (SBF) within the vertebrobasilar arteries, we evaluated 57 patients with sudden deafness using magnetic resonance imaging (MRI). We detected SBF in 12 (21%) patients, predominantly men over 50 years of age. A second MRI performed in 5 patients 2 months after the onset of symptoms showed recovery of blood flow. All 12 patients complained of vertigo. Audiological and neurotologic tests suggested that hearing loss mainly involved the inner ear. Our findings suggest that unless central lesions are detected, headache, hypoesthesia of the external ear canal, and electronystagmographic abnormalities are signs of SBF. Because sudden deafness may recur in patients who have SBF, they should be monitored and treated to prevent recurrence.
- Published
- 1993
- Full Text
- View/download PDF
49. Slow blood flow of the vertebrobasilar system in patients with dizziness and vertigo.
- Author
-
Kikuchi S, Kaga K, Yamasoba T, Higo R, O'Uchi T, and Tokumaru A
- Subjects
- Aged, Cerebrovascular Circulation physiology, Electronystagmography, Female, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Vertebrobasilar Insufficiency diagnosis, Dizziness etiology, Vertebrobasilar Insufficiency complications, Vertigo etiology
- Abstract
We evaluated 102 patients with dizziness or vertigo who were 50 years of age and over, using magnetic resonance imaging (MRI). Slow blood flow (SBF) in the vertebrobasilar system was detected in 36 patients (35%). The patients with SBF experienced dizziness or vertigo for a longer period than those without SBF. The apogeotrophic type of direction-changing nystagmus was observed in 10 of 36 patients with SBF. No significant differences were found between patients with and without SBF with other neurotological tests. Because MRI can detect both infarcts in the hind-brain and SBF in the vertebral and basilar arteries it is recommended for evaluation of vascular disorders in older patients with vestibular symptoms.
- Published
- 1993
- Full Text
- View/download PDF
50. NMR imaging of central nervous system diseases before and after radiotherapy.
- Author
-
O'Uchi T, Steiner RE, and McKenzie CG
- Subjects
- Adult, Astrocytoma radiotherapy, Brain Neoplasms radiotherapy, Female, Glioma radiotherapy, Humans, Intracranial Arteriovenous Malformations radiotherapy, Male, Middle Aged, Radiotherapy, High-Energy, Time Factors, Astrocytoma diagnosis, Brain Neoplasms diagnosis, Glioma diagnosis, Intracranial Arteriovenous Malformations diagnosis, Magnetic Resonance Spectroscopy
- Abstract
Two brain tumors, a foramen magnum tumor and an arterio-venous malformation (AVM) were treated with radiation but without chemotherapy or surgical removal. These cases were monitored by NMR imaging for a period of 16 months after radiotherapy to detect the response of the tumors and brain tissue to radiation. The T1 and T2 of the tumors behaved independently. T1 decreased after radiation related to clinical improvement. T2 did not change to the same degree as T1. An increased T2 area around the tumors and along the lateral ventricle developed about six months in one case and 16 months in the other case after radiotherapy, without associated clinical change in either case.
- Published
- 1984
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