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3. Variant STAT4 and Response to Ruxolitinib in an Autoinflammatory Syndrome

4. Human germline heterozygous gain-of-function STAT6 variants cause severe allergic disease

6. Paleo-Games: Using AI and Gamification to Generate an Unguided Tour of an Open World Virtual Environment for STEM Education

11. Transcription factor EGR2 controls homing and pathogenicity of TH17 cells in the central nervous system

12. A CTCF-binding site in the Mdm1-Il22-Ifng locus shapes cytokine expression profiles and plays a critical role in early Th1 cell fate specification

13. MicroRNA-directed pathway discovery elucidates an miR-221/222–mediated regulatory circuit in class switch recombination

17. Incorporating the Dynamics of Climate Change into the Deep Dive Virtual Reality Underwater Site Prediction System

25. Using Cooperative Multi-agent Systems to Support the Generation of Student Learning Profiles in the Deep Dive Land Bridge System

28. List Of Contributors

33. A dual role of Cohesin in DNA DSB repair.

36. DeepDive: The Use of Virtual Worlds to Create an Ethnography of an Ancient Civilization

39. PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory

41. MicroRNA-221 and -222 modulate intestinal inflammatory Th17 cell response as negative feedback regulators downstream of interleukin-23

43. The contemporary factors shaping the professional identity of occupational therapy lecturers : narratives in education, representation and regulation

44. Rapid Enhancer Remodeling and Transcription Factor Repurposing Enable High Magnitude Gene Induction upon Acute Activation of NK Cells

47. An Evaluation of a Group CBT Programme for Children with a Diagnosis of Autism Spectrum Disorder in a School Age Disability Service

48. Phase 1 double-blind randomized safety trial of the Janus kinase inhibitor tofacitinib in systemic lupus erythematosus

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