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4,160 results on '"O'Donnell, Michael A"'

8. Inflammatory myofibroblastic tumor of the urinary bladder: A systematic review of the literature and report of a case

Author

Hage, Lory, O'Donnell, Michael A, Abou Chakra, Mohamad, Kime, Amel, Sibony, Mathilde, Peyromaure, Michaël, and Duquesne, Igor

Subjects
Sarcoma, Metastasis, Crizotinib, Health
Abstract

Introduction: Inflammatory myofibroblastic tumors (IMTs) are intermediate-grade lesions that frequently recur and rarely metastasize. There are currently no guidelines on the management of bladder IMTs. This systematic review aims to describe the clinical presentation and compare the management options for bladder IMTs. Methods: A PubMed/Medline search was conducted, according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, using the following Mesh terms: ('inflammatory myofibroblastic') AND ('tumor') OR ('tumor') AND ('bladder') AND ('case report'). A total of 75 case reports were included in the analysis. Results: The mean age of the patients was 36 years. 65 of the cases initially presented with hematuria. 68 of the tumors stained positive for anaplastic lymphoma kinase, and 20 invaded the muscularis. Patients underwent either transurethral resection of the bladder tumor (TURBT) only (34), TURBT followed by complementary partial cystectomy (16), or TURBT followed by radical cystectomy (4). 36 and 9 of the cases underwent partial and radical cystectomy after the initial diagnosis, respectively. Cystectomies were performed using an open (74), laparoscopic (14), robotic-assisted (10), or unknown (2) approach. At a mean follow-up of 14 months, the recurrence and metastasis rates were about 9 and 4, respectively. In addition, we present the case of a 49-year-old woman with a bladder IMT who underwent TURBT followed by laparoscopic partial cystectomy. The patient remains tumor free postoperatively (follow-up period of 12 months). Conclusion: A complete surgical excision of the bladder IMT is crucial for the optimal management of these cases. Proper differentiation of this tumor from sarcoma or leiomyosarcoma leads to the best outcomes., Author(s): Lory Hage [1]; Michael A O'Donnell [2]; Mohamad Abou Chakra (corresponding author) [2]; Amel Kime [3]; Mathilde Sibony [3]; Michaël Peyromaure [1]; Igor Duquesne [1] INTRODUCTION Inflammatory myofibroblastic tumors [...]

Published
2024
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12. Bladder-sparing Therapy for Bacillus Calmette-Guérin–unresponsive Non–muscle-invasive Bladder Cancer: International Bladder Cancer Group Recommendations for Optimal Sequencing and Patient Selection

Author

Li, Roger, Hensley, Patrick J., Gupta, Shilpa, Al-Ahmadie, Hikmat, Babjuk, Marko, Black, Peter C., Brausi, Maurizio, Bree, Kelly K., Fernández, Mario I., Guo, Charles C., Horowitz, Amir, Lamm, Donald L., Lerner, Seth P., Lotan, Yair, Mariappan, Paramananthan, McConkey, David, Mertens, Laura S., Mir, Carmen, Ross, Jeffrey S., O’Donnell, Michael, Palou, Joan, Pohar, Kamal, Steinberg, Gary, Soloway, Mark, Spiess, Philippe E., Svatek, Robert S., Tan, Wei Shen, Taoka, Rikiya, Buckley, Roger, and Kamat, Ashish M.

Published
2024
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14. Correction for O’Donnell et al., Empirical audit and review and an assessment of evidentiary value in research on the psychological consequences of scarcity

Author

O'Donnell, Michael, Dev, Amelia S, Antonoplis, Stephen, Baum, Stephen M, Benedetti, Arianna H, Brown, N Derek, Carrillo, Belinda, Choi, Andrew L, Connor, Paul, Donnelly, Kristin, Ellwood-Lowe, Monica E, Foushee, Ruthe, Jansen, Rachel, Jarvis, Shoshana N, Lundell-Creagh, Ryan, Ocampo, Joseph M, Okafor, Gold N, Azad, Zahra Rahmani, Rosenblum, Michael, Schatz, Derek, Stein, Daniel H, Wang, Yilu, Moore, Don A, and Nelson, Leif D

Subjects
Accounting, Auditing and Accountability, Commerce, Management, Tourism and Services, Good Health and Well Being, Clean Water and Sanitation
Published
2022

20. Summary Judgment Motion Denied When Record Lacks Material Facts

Author

O'Donnell, Michael

Subjects
Summary judgments -- Laws, regulations and rules, Fraudulent conveyances -- Cases, Material facts (Law) -- Laws, regulations and rules, Company legal issue, Government regulation, Business, international
Abstract

What You Need to Know Adherence to Local Rules is Essential: The court emphasized the importance of compliance with local procedural rules, including the requirement to file a separate Statement [...]

Published
2024

21. Arizona Appeals Court Affirms Dismissal Of Negligence And Breach Of Duty Claims Against Settlement/Escrow Agent

Author

O'Donnell, Michael

Subjects
Arizona. Court of Appeals -- Powers and duties, Summary judgments -- Laws, regulations and rules, Disclosure of information -- Laws, regulations and rules, Escrows -- Laws, regulations and rules, Negligence -- Cases, Compromise and settlement -- Laws, regulations and rules, Company legal issue, Government regulation, Business, international
Abstract

Introduction In a recent case from the Arizona Court of Appeals, the Court affirmed a grant of summary judgment in favor of a settlement/escrow agent, finding no breach of duty [...]

Published
2024

24. Opportunities for Regulatory Changes to Promote Pediatric Device Innovation in the United States: Joint Recommendations From Pediatric Innovator Roundtables.

Author

Sanger, Terence, Chang, Anthony, Feaster, William, Taraman, Sharief, Afari, Nadine, Beauregard, Debra, Dethlefs, Brent, Ghere, Tiffani, Kabeer, Mustafa, Tolomiczenko, George, Billig, Michael, Brophy, Jon, Eskandanian, Kolaleh, Espinoza, Juan, Farrugia, Sherry, Harrison, Michael, Horvat, Christopher, Hoyen, Claudia, Koh, Chester, Komiyama, Allison, Nelson, Krista, Kulkarni, Omkar, Levy, Robert, Maher, Kevin, O'Donnell, Michael, Ponsky, Todd, Richmond, Frances, Richter, Jessica, Roy, Shuvo, Samir, Shreim, Suresh, Srinivasan, Stallworth, Charlette, Thekkedath, Usha, Toman, Kara, Wall, James, West, Leanne, and Wolff, Dawn

Subjects
Device, FDA, guidelines, pediatric, regulatory
Abstract

ObjectiveThe purpose of this report is to provide insight from pediatric stakeholders with a shared desire to facilitate a revision of the current United States regulatory pathways for the development of pediatric healthcare devices.MethodsOn August 5, 2020, a group of innovators, engineers, professors and clinicians met to discuss challenges and opportunities for the development of new medical devices for pediatric health and the importance of creating a regulatory environment that encourages and accelerates the research and development of such devices. On January 6, 2021, this group joined regulatory experts at a follow-up meeting.ResultsOne of the primary issues identified was the need to present decision-makers with opportunities that change the return-on-investment balance between adult and pediatric devices to promote investment in pediatric devices.Discussion/conclusionSeveral proposed strategies were discussed, and these strategies can be divided into two broad categories: 1. Removal of real and perceived barriers to pediatric device innovation; 2. Increasing incentives for pediatric device innovation.

Published
2021

28. A Phase 1 Trial of Durvalumab in Combination with Bacillus Calmette-Guerin (BCG) or External Beam Radiation Therapy in Patients with BCG-unresponsive Non-muscle-Invasive Bladder Cancer: The Hoosier Cancer Research Network GU16-243 ADAPT-BLADDER Study

Author

Hahn, Noah M., O'Donnell, Michael A., Efstathiou, Jason A., Zahurak, Marianna, Rosner, Gary L., Smith, Jeff, Kates, Max R., Bivalacqua, Trinity J., Tran, Phuoc T., Song, Daniel Y., Baras, Alex S., Matoso, Andres, Choi, Woonyoung, Smith, Kellie N., Pardoll, Drew M., Marchionni, Luigi, McGuire, Bridget, Grace Phelan, Mary, Johnson, Burles A., III, O'Neal, Tanya, McConkey, David J., Rose, Tracy L., Bjurlin, Marc, Lim, Emerson A., Drake, Charles G., McKiernan, James M., Deutsch, Israel, Anderson, Christopher B., Lamm, Donald L., Geynisman, Daniel M., Plimack, Elizabeth R., Hallman, Mark A., Horwitz, Eric M., Al-Saleem, Essel, Chen, David Y.T., Greenberg, Richard E., Kutikov, Alexander, Guo, Gordon, Masterson, Timothy A., Adra, Nabil, and Kaimakliotis, Hristos Z.

Published
2023
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34. Empirical audit and review and an assessment of evidentiary value in research on the psychological consequences of scarcity

Author

O’Donnell, Michael, Dev, Amelia S., Antonoplis, Stephen, Baum, Stephen M., Benedetti, Arianna H., Brown, N. Derek, Carrillo, Belinda, Choi, Andrew L., Connor, Paul, Donnelly, Kristin, Ellwood-Lowe, Monica E., Foushee, Ruthe, Jansen, Rachel, Jarvis, Shoshana N., Lundell-Creagh, Ryan, Ocampo, Joseph M., Okafor, Gold N., Azad, Zahra Rahmani, Rosenblum, Michael, Schatz, Derek, Stein, Daniel H., Wang, Yilu, Moore, Don A., and Nelson, Leif D.

Published
2021

35. Educational inequality : race, schools and urban development in Phoenix, 1968-1982

Author

O'Donnell, Michael and Collins, Bruce

Subjects
379.2
Abstract

This thesis argues that to understand why bilingual education did not achieve its aims, the program must be analysed within an urban history context of residential and school segregation in Phoenix. When passed by Congress in 1968, the Bilingual Education Act (BEA) was considered the signature civil rights achievement for Latinos of that era. Ten years later, bilingual education was increasingly considered ineffectual and failed to effect a meaningful change in the attainment gap between Latinos and their Anglo classmates, as was the main objective of the BEA 1968. By focusing upon Phoenix, Arizona between 1968 and 1982, this thesis argues that bilingual education and the place of Mexican Americans in the southwest was fundamentally contested in ways that historians have not fully captured in previous works. This thesis contributes to knowledge by showing that unlike in other Sunbelt locations, in Arizona bilingual education was opposed by conservative politicians throughout this period and its survival remained uncertain. Although hopes for accessing the opportunities granted by Great Society legislation were curtailed by this opposition, it was a series of urban development, school site selection and school desegregation policies which undermined the effectiveness of Phoenix schools in ways that bilingual education could not remedy. These policies created an unequal metropolitan landscape that was reflected in the increasingly racially imbalanced enrolments in Phoenix schools. Ultimately, they caused the closure of inner-city high schools and, by 1982, the creation of a thirty square mile radius without a school. This narrative of underlying discrimination against Mexican Americans also contributes to knowledge by challenging the contemporary marketing of Phoenix as a modern, racially tolerant city. In many cases, Mexican Americans were subject to many of the same prejudiced practices that African Americans were subject to in other Sunbelt cities. Yet, some Mexican American public figures were able to escape the worst excesses of racism. This thesis, therefore, examines the complex environment in which Mexican American racial identities evolved during this period, as the community attempted to navigate the challenges of race4 making state practices and the opportunities that the introduction of bilingual education brought with it.

Published
2019

36. Title Nerds Season 3, Episode 3

Author

O'Donnell, Michael

Subjects
Business, international
Abstract

Co-hosts Michael R. O'Donnell and Bethany A. Abele welcomed special guest Scott Sumner, Vice President and Underwriting Counsel of Fidelity National Financial, who has played various roles in his 21-year [...]

Published
2024

37. Doctrine Of Lis Pendens And Overall Delay Render Motion To Intervene In An Ohio Foreclosure Untimely

Author

O'Donnell, Michael

Subjects
Foreclosure -- Cases, Intervention (Civil procedure) -- Cases, Lis pendens -- Cases, Judgments -- Cases, Company legal issue, Business, international
Abstract

Introduction In a recent case from the Court of Appeals of Ohio, the Court assessed the timeliness of a third-party's motion to intervene in a foreclosure litigation. The court ultimately [...]

Published
2024

38. Failure To Disclose Right Of First Refusal Dooms Home Sale

Author

O'Donnell, Michael

Subjects
Right of first refusal -- Cases -- Laws, regulations and rules, Disclosure of information -- Cases -- Laws, regulations and rules, House selling -- Cases -- Laws, regulations and rules, Company legal issue, Government regulation, Business, international
Abstract

Introduction In a recent decision, the New Jersey Appellate Division decided whether a right of first refusal clause in a prior deed constituted a restriction on the alienability of a [...]

Published
2024

39. Colorado Federal Court Rejects Insured's Claim For Defense And Indemnity For Mechanic's Liens

Author

O'Donnell, Michael

Subjects
Mechanics' liens -- Cases, Company legal issue, Business, international
Abstract

Introduction Northmarq Finance, a Nebraska limited liability company, had a title insurance policy with Fidelity National Title Insurance Company. Northmarq sued Fidelity seeking coverage under the policy after several subcontractors [...]

Published
2024

40. 5-Year Failure To Provide Title Claim Notice Relieves Underwriter Of Duty To Defend

Author

O'Donnell, Michael

Subjects
Duty to defend (Insurance law) -- Cases, Notice (Law) -- Cases, Company legal issue, Business, international, Federal Rules of Civil Procedure
Abstract

Introduction In a recent case from the United States District Court for the District of Nevada, the Court examined whether the duty to defend is triggered when a lender fails [...]

Published
2024

48. Cilia structure and intraflagellar transport differentially regulate sensory response dynamics within and between C. elegans chemosensory neurons.

Author

Philbrook, Alison, O'Donnell, Michael P., Grunenkovaite, Laura, and Sengupta, Piali

Subjects
*SENSORY neurons, *CAENORHABDITIS elegans, *CYTOSKELETAL proteins, *CILIA & ciliary motion, *NEURONS, *OLFACTORY receptors
Abstract

Sensory neurons contain morphologically diverse primary cilia that are built by intraflagellar transport (IFT) and house sensory signaling molecules. Since both ciliary structural and signaling proteins are trafficked via IFT, it has been challenging to decouple the contributions of IFT and cilia structure to neuronal responses. By acutely inhibiting IFT without altering cilia structure and vice versa, here we describe the differential roles of ciliary trafficking and sensory ending morphology in shaping chemosensory responses in Caenorhabditis elegans. We show that a minimum cilium length but not continuous IFT is necessary for a subset of responses in the ASH nociceptive neurons. In contrast, neither cilia nor continuous IFT are necessary for odorant responses in the AWA olfactory neurons. Instead, continuous IFT differentially modulates response dynamics in AWA. Upon acute inhibition of IFT, cilia-destined odorant receptors are shunted to ectopic branches emanating from the AWA cilia base. Spatial segregation of receptors in these branches from a cilia-restricted regulatory kinase results in odorant desensitization defects, highlighting the importance of precise organization of signaling molecules at sensory endings in regulating response dynamics. We also find that adaptation of AWA responses upon repeated exposure to an odorant is mediated by IFT-driven removal of its cognate receptor, whereas adaptation to a second odorant is regulated via IFT-independent mechanisms. Our results reveal unexpected complexity in the contribution of IFT and cilia organization to the regulation of responses even within a single chemosensory neuron type and establish a critical role for these processes in the precise modulation of olfactory behaviors. The relative contributions of intraflagellar transport (IFT) and cilia structure to sensory neuron responses remains unclear. This study reveals unexpected complexity in the contribution of IFT and cilia organization to C. elegans chemosensory neuron responses and the precise modulation of olfactory behavior. [ABSTRACT FROM AUTHOR]

Published
2024
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49. A Multinational, Multi-Institutional Study Assessing the Impact of Diabetes Mellitus on the Prognosis of Patients with Non-Muscle Invasive Bladder Cancer Treated with Bacillus Calmette-Guérin.

Author

Abou Chakra, Mohamad, Duquesne, Igor, Peyromaure, Michael, Mott, Sarah L., Moussa, Mohamad, and O'Donnell, Michael A

Subjects
NON-muscle invasive bladder cancer, INTRAVESICAL administration, BCG vaccines, TERTIARY care, DESCRIPTIVE statistics, MULTIVARIATE analysis, LONGITUDINAL method, TYPE 2 diabetes, RESEARCH, PROPORTIONAL hazards models, DISEASE complications
Abstract

The study aimed to examine the impact of diabetes mellitus type 2 (DMII) on the oncological outcomes of non-muscle invasive bladder cancer (NMIBC) treated with Bacillus Calmette-Guérin (BCG) using comprehensive real-world data. We performed an analysis of data on NMIBC patients treated with BCG from the United States (US) National Phase II BCG/Interferon (IFN) trial database (125 centers) and pooled databases from three tertiary care institutions: France (FR), Lebanon (LB) (2000–2021), and the US (University of Iowa) (2011–2021). There were 867 patients from the Phase II trial, 1232 from the FR/LB cohort, and 233 from the US (Iowa) cohort (n = 2332). DM II was reported in 13% of the Phase II trial cohort, 14.4% of the FR/LB cohort, and 33.5% of the US (Iowa) cohort. The median follow-up was 24 months in the Phase II trial cohort, 25 months in the FR/LB cohort, and 48 months in the US (Iowa) cohort. In multivariable Cox regression analyses, DMII was not significantly associated with recurrence or progression of the tumor in any of the cohorts included in this study. DMII may not be a clinical prognostic factor for NMIBC patients treated with BCG. Prospective evaluation is needed. [ABSTRACT FROM AUTHOR]

Published
2024
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