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1. P068 Knowledge Translation for Implementation of Point-of-Care Technology (POCT) in Breast Cancer Survivors in Africa: Descriptive study

Author: Milambo, J.P.M., primary, Nyasulu, P.S., additional, Akudugu, J.M., additional, Ndirangu, J., additional, and Niyukuri, D., additional
Published: 2023
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2. Global injury morbidity and mortality from 1990 to 2017: results from the Global Burden of Disease Study 2017.

Author: James S.L., Castle C.D., Dingels Z.V., Fox J.T., Hamilton E.B., Liu Z., S Roberts N.L., Sylte D.O., Henry N.J., LeGrand K.E., Abdelalim A., Abdoli A., Abdollahpour I., Abdulkader R.S., Abedi A., Abosetugn A.E., Abushouk A.I., Adebayo O.M., Agudelo-Botero M., Ahmad T., Ahmed R., Ahmed M.B., Eddine Aichour M.T., Alahdab F., Alamene G.M., Alanezi F.M., Alebel A., Alema N.M., Alghnam S.A., Al-Hajj S., Ali B.A., Ali S., Alikhani M., Alinia C., Alipour V., Aljunid S.M., Almasi-Hashiani A., Almasri N.A., Altirkawi K., Abdeldayem Amer Y.S., Amini S., Loreche Amit A.M., Andrei C.L., Ansari-Moghaddam A., T Antonio C.A., Yaw Appiah S.C., Arabloo J., Arab-Zozani M., Arefi Z., Aremu O., Ariani F., Arora A., Asaad M., Asghari B., Awoke N., Ayala Quintanilla B.P., Ayano G., Ayanore M.A., Azari S., Azarian G., Badawi A., Badiye A.D., Bagli E., Baig A.A., Bairwa M., Bakhtiari A., Balachandran A., Banach M., Banerjee S.K., Banik P.C., Banstola A., Barker-Collo S.L., Barnighausen T.W., Barrero L.H., Barzegar A., Bayati M., Baye B.A., Bedi N., Behzadifar M., Bekuma T.T., Belete H., Benjet C., Bennett D.A., Bensenor I.M., Berhe K., Bhardwaj P., Bhat A.G., Bhattacharyya K., Bibi S., Bijani A., Bin Sayeed M.S., Borges G., Borzi A.M., Boufous S., Brazinova A., Briko N.I., Budhathoki S.S., Car J., Cardenas R., Carvalho F., Castaldelli-Maia J.M., Castaneda-Orjuela C.A., Castelpietra G., Catala-Lopez F., Cerin E., Chandan J.S., Chanie W.F., Chattu S.K., Chattu V.K., Chatziralli I., Chaudhary N., Cho D.Y., Kabir Chowdhury M.A., Chu D.-T., Colquhoun S.M., Constantin M.-M., Costa V.M., Damiani G., Daryani A., Davila-Cervantes C.A., Demeke F.M., Demis A.B., Demoz G.T., Demsie D.G., Derakhshani A., Deribe K., Desai R., Nasab M.D., da Silva D.D., Dibaji Forooshani Z.S., Doyle K.E., Driscoll T.R., Dubljanin E., Adema B.D., Eagan A.W., Eftekhari A., Ehsani-Chimeh E., Sayed Zaki M.E., Elemineh D.A., El-Jaafary S.I., El-Khatib Z., Ellingsen C.L., Emamian M.H., Endalew D.A., Eskandarieh S., Faris P.S., Faro A., Farzadfar F., Fatahi Y., Fekadu W., Ferede T.Y., Fereshtehnejad S.-M., Fernandes E., Ferrara P., Feyissa G.T., Filip I., Fischer F., Folayan M.O., Foroutan M., Francis J.M., Franklin R.C., Fukumoto T., Geberemariyam B.S., Gebre A.K., Gebremedhin K.B., Gebremeskel G.G., Gebremichael B., Gedefaw G.A., Geta B., Ghafourifard M., Ghamari F., Ghashghaee A., Gholamian A., Gill T.K., Goulart A.C., Grada A., Grivna M., Mohialdeen Gubari M.I., Guimaraes R.A., Guo Y., Gupta G., Haagsma J.A., Hafezi-Nejad N., Bidgoli H.H., Hall B.J., Hamadeh R.R., Hamidi S., Haro J.M., Hasan M.M., Hasanzadeh A., Hassanipour S., Hassankhani H., Hassen H.Y., Havmoeller R., Hayat K., Hendrie D., Heydarpour F., Hijar M., Ho H.C., Hoang C.L., Hole M.K., Holla R., Hossain N., Hosseinzadeh M., Hostiuc S., Hu G., Ibitoye S.E., Ilesanmi O.S., Ilic I., Ilic M.D., Inbaraj L.R., Indriasih E., Naghibi Irvani S.S., Shariful Islam S.M., Islam M.M., Ivers R.Q., Jacobsen K.H., Jahani M.A., Jahanmehr N., Jakovljevic M., Jalilian F., Jayaraman S., Jayatilleke A.U., Jha R.P., John-Akinola Y.O., Jonas J.B., Joseph N., Joukar F., Jozwiak J.J., Jungari S.B., Jurisson M., Kabir A., Kadel R., Kahsay A., Kalankesh L.R., Kalhor R., Kamil T.A., Kanchan T., Kapoor N., Karami M., Kasaeian A., Kassaye H.G., Kavetskyy T., Kebede H.K., Keiyoro P.N., Kelbore A.G., Kelkay B., Khader Y.S., Khafaie M.A., Khalid N., Khalil I.A., Khalilov R., Khammarnia M., Khan E.A., Khan M., Khanna T., Khazaie H., Shadmani F.K., Khundkar R., Kiirithio D.N., Kim Y.-E., Kim D., Kim Y.J., Kisa A., Kisa S., Komaki H., M Kondlahalli S.K., Korshunov V.A., Koyanagi A., G Kraemer M.U., Krishan K., Bicer B.K., Kugbey N., Kumar V., Kumar N., Kumar G.A., Kumar M., Kumaresh G., Kurmi O.P., Kuti O., Vecchia C., Lami F.H., Lamichhane P., Lang J.J., Lansingh V.C., Laryea D.O., Lasrado S., Latifi A., Lauriola P., Leasher J.L., Huey Lee S.W., Lenjebo T.L., Levi M., Li S., Linn S., Liu X., Lopez A.D., Lotufo P.A., Lunevicius R., Lyons R.A., Madadin M., El Razek M.M.A., Mahotra N.B., Majdan M., Majeed A., Malagon-Rojas J.N., Maled V., Malekzadeh R., Malta D.C., Manafi N., Manafi A., Manda A.-L., Manjunatha N., Mansour-Ghanaei F., Mansouri B., Mansournia M.A., Maravilla J.C., March L.M., Mason-Jones A.J., Masoumi S.Z., Massenburg B.B., Maulik P.K., Meles G.G., Melese A., Melketsedik Z.A., N Memiah P.T., Mendoza W., Menezes R.G., Mengesha M.B., Mengesha M.M., Meretoja T.J., Meretoja A., Merie H.E., Mestrovic T., Miazgowski B., Miazgowski T., Miller T.R., Mini G.K., Mirica A., Mirrakhimov E.M., Mirzaei-Alavijeh M., Mithra P., Moazen B., Moghadaszadeh M., Mohamadi E., Mohammad Y., Mohammad K.A., Darwesh A.M., Gholi Mezerji N.M., Mohammadian-Hafshejani A., Mohammadoo-Khorasani M., Mohammadpourhodki R., Mohammed S., Mohammed J.A., Mohebi F., Molokhia M., Monasta L., Moodley Y., Moosazadeh M., Moradi M., Moradi G., Moradi-Lakeh M., Moradpour F., Morawska L., Velasquez I.M., Morisaki N., Morrison S.D., Mossie T.B., Muluneh A.G., Murthy S., Musa K.I., Mustafa G., Nabhan A.F., Nagarajan A.J., Naik G., Naimzada M.D., Najafi F., Nangia V., Nascimento B.R., Naserbakht M., Nayak V., Ndwandwe D.E., Negoi I., Ngunjiri J.W., Nguyen C.T., Thi Nguyen H.L., Nikbakhsh R., Anggraini Ningrum D.N., Nnaji C.A., Nyasulu P.S., Ogbo F.A., Oghenetega O.B., Oh I.-H., Okunga E.W., Olagunju A.T., Olagunju T.O., Bali A.O., Onwujekwe O.E., Asante K.O., Orpana H.M., Ota E., Otstavnov N., Otstavnov S.S., A M.P., Padubidri J.R., Pakhale S., Pakshir K., Panda-Jonas S., Park E.-K., Patel S.K., Pathak A., Pati S., Patton G.C., Paulos K., Peden A.E., Filipino Pepito V.C., Pereira J., Pham H.Q., Phillips M.R., Pinheiro M., Polibin R.V., Polinder S., Poustchi H., Prakash S., Angga Pribadi D.R., Puri P., Syed Z.Q., Rabiee M., Rabiee N., Radfar A., Rafay A., Rafiee A., Rafiei A., Rahim F., Rahimi S., Rahimi-Movaghar V., Rahman M.A., Rajabpour-Sanati A., Rajati F., Rakovac I., Ranganathan K., Rao S.J., Rashedi V., Rastogi P., Rathi P., Rawaf S., Rawal L., Rawassizadeh R., Renjith V., N Renzaho A.M., Resnikoff S., Rezapour A., Ribeiro A.I., Rickard J., Rios Gonzalez C.M., Ronfani L., Roshandel G., Saad A.M., Sabde Y.D., Sabour S., Saddik B., Safari S., Safari-Faramani R., Safarpour H., Safdarian M., Sajadi S.M., Salamati P., Salehi F., Zahabi S.S., Rashad Salem M.R., Salem H., Salman O., Salz I., Samy A.M., Sanabria J., Riera L.S., Santric Milicevic M.M., Sarker A.R., Sarveazad A., Sathian B., Sawhney M., Sawyer S.M., Saxena S., Sayyah M., Schwebel D.C., Seedat S., Senthilkumaran S., Sepanlou S.G., Seyedmousavi S., Sha F., Shaahmadi F., Shahabi S., Shaikh M.A., Shams-Beyranvand M., Shamsizadeh M., Sharif-Alhoseini M., Sharifi H., Sheikh A., Shigematsu M., Shin J.I., Shiri R., Siabani S., Sigfusdottir I.D., Singh P.K., Singh J.A., Sinha D.N., Smarandache C.-G., R Smith E.U., Soheili A., Soleymani B., Soltanian A.R., Soriano J.B., Sorrie M.B., Soyiri I.N., Stein D.J., Stokes M.A., Sufiyan M.B., Rasul Suleria H.A., Sykes B.L., Tabares-Seisdedos R., Tabb K.M., Taddele B.W., Tadesse D.B., Tamiru A.T., Tarigan I.U., Tefera Y.M., Tehrani-Banihashemi A., Tekle M.G., Tekulu G.H., Tesema A.K., Tesfay B.E., Thapar R., Tilahune A.B., Tlaye K.G., Tohidinik H.R., Topor-Madry R., Tran B.X., Tran K.B., Tripathy J.P., Tsai A.C., Car L.T., Ullah S., Ullah I., Umar M., Unnikrishnan B., Upadhyay E., Uthman O.A., Valdez P.R., Vasankari T.J., Venketasubramanian N., Violante F.S., Vlassov V., Waheed Y., Weldesamuel G.T., Werdecker A., Wiangkham T., Wolde H.F., Woldeyes D.H., Wondafrash D.Z., Wondmeneh T.G., Wondmieneh A.B., Wu A.-M., Yadav R., Yadollahpour A., Yano Y., Yaya S., Yazdi-Feyzabadi V., Yip P., Yisma E., Yonemoto N., Yoon S.-J., Youm Y., Younis M.Z., Yousefi Z., Yu Y., Yu C., Yusefzadeh H., Moghadam T.Z., Zaidi Z., Zaman S.B., Zamani M., Zamanian M., Zandian H., Zarei A., Zare F., Zhang Z.-J., Zhang Y., Zodpey S., Dandona L., Dandona R., Degenhardt L., Dharmaratne S.D., Hay S.I., Mokdad A.H., Reiner R.C., Sartorius B., Vos T., James S.L., Castle C.D., Dingels Z.V., Fox J.T., Hamilton E.B., Liu Z., S Roberts N.L., Sylte D.O., Henry N.J., LeGrand K.E., Abdelalim A., Abdoli A., Abdollahpour I., Abdulkader R.S., Abedi A., Abosetugn A.E., Abushouk A.I., Adebayo O.M., Agudelo-Botero M., Ahmad T., Ahmed R., Ahmed M.B., Eddine Aichour M.T., Alahdab F., Alamene G.M., Alanezi F.M., Alebel A., Alema N.M., Alghnam S.A., Al-Hajj S., Ali B.A., Ali S., Alikhani M., Alinia C., Alipour V., Aljunid S.M., Almasi-Hashiani A., Almasri N.A., Altirkawi K., Abdeldayem Amer Y.S., Amini S., Loreche Amit A.M., Andrei C.L., Ansari-Moghaddam A., T Antonio C.A., Yaw Appiah S.C., Arabloo J., Arab-Zozani M., Arefi Z., Aremu O., Ariani F., Arora A., Asaad M., Asghari B., Awoke N., Ayala Quintanilla B.P., Ayano G., Ayanore M.A., Azari S., Azarian G., Badawi A., Badiye A.D., Bagli E., Baig A.A., Bairwa M., Bakhtiari A., Balachandran A., Banach M., Banerjee S.K., Banik P.C., Banstola A., Barker-Collo S.L., Barnighausen T.W., Barrero L.H., Barzegar A., Bayati M., Baye B.A., Bedi N., Behzadifar M., Bekuma T.T., Belete H., Benjet C., Bennett D.A., Bensenor I.M., Berhe K., Bhardwaj P., Bhat A.G., Bhattacharyya K., Bibi S., Bijani A., Bin Sayeed M.S., Borges G., Borzi A.M., Boufous S., Brazinova A., Briko N.I., Budhathoki S.S., Car J., Cardenas R., Carvalho F., Castaldelli-Maia J.M., Castaneda-Orjuela C.A., Castelpietra G., Catala-Lopez F., Cerin E., Chandan J.S., Chanie W.F., Chattu S.K., Chattu V.K., Chatziralli I., Chaudhary N., Cho D.Y., Kabir Chowdhury M.A., Chu D.-T., Colquhoun S.M., Constantin M.-M., Costa V.M., Damiani G., Daryani A., Davila-Cervantes C.A., Demeke F.M., Demis A.B., Demoz G.T., Demsie D.G., Derakhshani A., Deribe K., Desai R., Nasab M.D., da Silva D.D., Dibaji Forooshani Z.S., Doyle K.E., Driscoll T.R., Dubljanin E., Adema B.D., Eagan A.W., Eftekhari A., Ehsani-Chimeh E., Sayed Zaki M.E., Elemineh D.A., El-Jaafary S.I., El-Khatib Z., Ellingsen C.L., Emamian M.H., Endalew D.A., Eskandarieh S., Faris P.S., Faro A., Farzadfar F., Fatahi Y., Fekadu W., Ferede T.Y., Fereshtehnejad S.-M., Fernandes E., Ferrara P., Feyissa G.T., Filip I., Fischer F., Folayan M.O., Foroutan M., Francis J.M., Franklin R.C., Fukumoto T., Geberemariyam B.S., Gebre A.K., Gebremedhin K.B., Gebremeskel G.G., Gebremichael B., Gedefaw G.A., Geta B., Ghafourifard M., Ghamari F., Ghashghaee A., Gholamian A., Gill T.K., Goulart A.C., Grada A., Grivna M., Mohialdeen Gubari M.I., Guimaraes R.A., Guo Y., Gupta G., Haagsma J.A., Hafezi-Nejad N., Bidgoli H.H., Hall B.J., Hamadeh R.R., Hamidi S., Haro J.M., Hasan M.M., Hasanzadeh A., Hassanipour S., Hassankhani H., Hassen H.Y., Havmoeller R., Hayat K., Hendrie D., Heydarpour F., Hijar M., Ho H.C., Hoang C.L., Hole M.K., Holla R., Hossain N., Hosseinzadeh M., Hostiuc S., Hu G., Ibitoye S.E., Ilesanmi O.S., Ilic I., Ilic M.D., Inbaraj L.R., Indriasih E., Naghibi Irvani S.S., Shariful Islam S.M., Islam M.M., Ivers R.Q., Jacobsen K.H., Jahani M.A., Jahanmehr N., Jakovljevic M., Jalilian F., Jayaraman S., Jayatilleke A.U., Jha R.P., John-Akinola Y.O., Jonas J.B., Joseph N., Joukar F., Jozwiak J.J., Jungari S.B., Jurisson M., Kabir A., Kadel R., Kahsay A., Kalankesh L.R., Kalhor R., Kamil T.A., Kanchan T., Kapoor N., Karami M., Kasaeian A., Kassaye H.G., Kavetskyy T., Kebede H.K., Keiyoro P.N., Kelbore A.G., Kelkay B., Khader Y.S., Khafaie M.A., Khalid N., Khalil I.A., Khalilov R., Khammarnia M., Khan E.A., Khan M., Khanna T., Khazaie H., Shadmani F.K., Khundkar R., Kiirithio D.N., Kim Y.-E., Kim D., Kim Y.J., Kisa A., Kisa S., Komaki H., M Kondlahalli S.K., Korshunov V.A., Koyanagi A., G Kraemer M.U., Krishan K., Bicer B.K., Kugbey N., Kumar V., Kumar N., Kumar G.A., Kumar M., Kumaresh G., Kurmi O.P., Kuti O., Vecchia C., Lami F.H., Lamichhane P., Lang J.J., Lansingh V.C., Laryea D.O., Lasrado S., Latifi A., Lauriola P., Leasher J.L., Huey Lee S.W., Lenjebo T.L., Levi M., Li S., Linn S., Liu X., Lopez A.D., Lotufo P.A., Lunevicius R., Lyons R.A., Madadin M., El Razek M.M.A., Mahotra N.B., Majdan M., Majeed A., Malagon-Rojas J.N., Maled V., Malekzadeh R., Malta D.C., Manafi N., Manafi A., Manda A.-L., Manjunatha N., Mansour-Ghanaei F., Mansouri B., Mansournia M.A., Maravilla J.C., March L.M., Mason-Jones A.J., Masoumi S.Z., Massenburg B.B., Maulik P.K., Meles G.G., Melese A., Melketsedik Z.A., N Memiah P.T., Mendoza W., Menezes R.G., Mengesha M.B., Mengesha M.M., Meretoja T.J., Meretoja A., Merie H.E., Mestrovic T., Miazgowski B., Miazgowski T., Miller T.R., Mini G.K., Mirica A., Mirrakhimov E.M., Mirzaei-Alavijeh M., Mithra P., Moazen B., Moghadaszadeh M., Mohamadi E., Mohammad Y., Mohammad K.A., Darwesh A.M., Gholi Mezerji N.M., Mohammadian-Hafshejani A., Mohammadoo-Khorasani M., Mohammadpourhodki R., Mohammed S., Mohammed J.A., Mohebi F., Molokhia M., Monasta L., Moodley Y., Moosazadeh M., Moradi M., Moradi G., Moradi-Lakeh M., Moradpour F., Morawska L., Velasquez I.M., Morisaki N., Morrison S.D., Mossie T.B., Muluneh A.G., Murthy S., Musa K.I., Mustafa G., Nabhan A.F., Nagarajan A.J., Naik G., Naimzada M.D., Najafi F., Nangia V., Nascimento B.R., Naserbakht M., Nayak V., Ndwandwe D.E., Negoi I., Ngunjiri J.W., Nguyen C.T., Thi Nguyen H.L., Nikbakhsh R., Anggraini Ningrum D.N., Nnaji C.A., Nyasulu P.S., Ogbo F.A., Oghenetega O.B., Oh I.-H., Okunga E.W., Olagunju A.T., Olagunju T.O., Bali A.O., Onwujekwe O.E., Asante K.O., Orpana H.M., Ota E., Otstavnov N., Otstavnov S.S., A M.P., Padubidri J.R., Pakhale S., Pakshir K., Panda-Jonas S., Park E.-K., Patel S.K., Pathak A., Pati S., Patton G.C., Paulos K., Peden A.E., Filipino Pepito V.C., Pereira J., Pham H.Q., Phillips M.R., Pinheiro M., Polibin R.V., Polinder S., Poustchi H., Prakash S., Angga Pribadi D.R., Puri P., Syed Z.Q., Rabiee M., Rabiee N., Radfar A., Rafay A., Rafiee A., Rafiei A., Rahim F., Rahimi S., Rahimi-Movaghar V., Rahman M.A., Rajabpour-Sanati A., Rajati F., Rakovac I., Ranganathan K., Rao S.J., Rashedi V., Rastogi P., Rathi P., Rawaf S., Rawal L., Rawassizadeh R., Renjith V., N Renzaho A.M., Resnikoff S., Rezapour A., Ribeiro A.I., Rickard J., Rios Gonzalez C.M., Ronfani L., Roshandel G., Saad A.M., Sabde Y.D., Sabour S., Saddik B., Safari S., Safari-Faramani R., Safarpour H., Safdarian M., Sajadi S.M., Salamati P., Salehi F., Zahabi S.S., Rashad Salem M.R., Salem H., Salman O., Salz I., Samy A.M., Sanabria J., Riera L.S., Santric Milicevic M.M., Sarker A.R., Sarveazad A., Sathian B., Sawhney M., Sawyer S.M., Saxena S., Sayyah M., Schwebel D.C., Seedat S., Senthilkumaran S., Sepanlou S.G., Seyedmousavi S., Sha F., Shaahmadi F., Shahabi S., Shaikh M.A., Shams-Beyranvand M., Shamsizadeh M., Sharif-Alhoseini M., Sharifi H., Sheikh A., Shigematsu M., Shin J.I., Shiri R., Siabani S., Sigfusdottir I.D., Singh P.K., Singh J.A., Sinha D.N., Smarandache C.-G., R Smith E.U., Soheili A., Soleymani B., Soltanian A.R., Soriano J.B., Sorrie M.B., Soyiri I.N., Stein D.J., Stokes M.A., Sufiyan M.B., Rasul Suleria H.A., Sykes B.L., Tabares-Seisdedos R., Tabb K.M., Taddele B.W., Tadesse D.B., Tamiru A.T., Tarigan I.U., Tefera Y.M., Tehrani-Banihashemi A., Tekle M.G., Tekulu G.H., Tesema A.K., Tesfay B.E., Thapar R., Tilahune A.B., Tlaye K.G., Tohidinik H.R., Topor-Madry R., Tran B.X., Tran K.B., Tripathy J.P., Tsai A.C., Car L.T., Ullah S., Ullah I., Umar M., Unnikrishnan B., Upadhyay E., Uthman O.A., Valdez P.R., Vasankari T.J., Venketasubramanian N., Violante F.S., Vlassov V., Waheed Y., Weldesamuel G.T., Werdecker A., Wiangkham T., Wolde H.F., Woldeyes D.H., Wondafrash D.Z., Wondmeneh T.G., Wondmieneh A.B., Wu A.-M., Yadav R., Yadollahpour A., Yano Y., Yaya S., Yazdi-Feyzabadi V., Yip P., Yisma E., Yonemoto N., Yoon S.-J., Youm Y., Younis M.Z., Yousefi Z., Yu Y., Yu C., Yusefzadeh H., Moghadam T.Z., Zaidi Z., Zaman S.B., Zamani M., Zamanian M., Zandian H., Zarei A., Zare F., Zhang Z.-J., Zhang Y., Zodpey S., Dandona L., Dandona R., Degenhardt L., Dharmaratne S.D., Hay S.I., Mokdad A.H., Reiner R.C., Sartorius B., and Vos T.
Abstract: BACKGROUND: Past research in population health trends has shown that injuries form a substantial burden of population health loss. Regular updates to injury burden assessments are critical. We report Global Burden of Disease (GBD) 2017 Study estimates on morbidity and mortality for all injuries. METHOD(S): We reviewed results for injuries from the GBD 2017 study. GBD 2017 measured injury-specific mortality and years of life lost (YLLs) using the Cause of Death Ensemble model. To measure non-fatal injuries, GBD 2017 modelled injury-specific incidence and converted this to prevalence and years lived with disability (YLDs). YLLs and YLDs were summed to calculate disability-adjusted life years (DALYs). FINDINGS: In 1990, there were 4 260 493 (4 085 700 to 4 396 138) injury deaths, which increased to 4 484 722 (4 332 010 to 4 585 554) deaths in 2017, while age-standardised mortality decreased from 1079 (1073 to 1086) to 738 (730 to 745) per 100000. In 1990, there were 354064302 (95% uncertainty interval: 338174876 to 371 610 802) new cases of injury globally, which increased to 520 710 288 (493 430 247 to 547 988 635) new cases in 2017. During this time, age-standardised incidence decreased non-significantly from 6824 (6534 to 7147) to 6763 (6412 to 7118) per 100000. Between 1990 and 2017, age-standardised DALYs decreased from 4947 (4655 to 5233) per 100000 to 3267 (3058 to 3505). INTERPRETATION: Injuries are an important cause of health loss globally, though mortality has declined between 1990 and 2017. Future research in injury burden should focus on prevention in high-burden populations, improving data collection and ensuring access to medical care.Copyright © Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ.
Published: 2021

3. Global injury morbidity and mortality from 1990 to 2017: Results from the global burden of disease study 2017

Author: James, S.L. Castle, C.D. Dingels, Z.V. Fox, J.T. Hamilton, E.B. Liu, Z. Roberts, N.L.S. Sylte, D.O. Henry, N.J. LeGrand, K.E. Abdelalim, A. Abdoli, A. Abdollahpour, I. Abdulkader, R.S. Abedi, A. Abosetugn, A.E. Abushouk, A.I. Adebayo, O.M. Agudelo-Botero, M. Ahmad, T. Ahmed, R. Ahmed, M.B. Aichour, M.T.E. Alahdab, F. Alamene, G.M. Alanezi, F.M. Alebel, A. Alema, N.M. Alghnam, S.A. Al-Hajj, S. Ali, B.A. Ali, S. Alikhani, M. Alinia, C. Alipour, V. Aljunid, S.M. Almasi-Hashiani, A. Almasri, N.A. Altirkawi, K. Amer, Y.S.A. Amini, S. Amit, A.M.L. Andrei, C.L. Ansari-Moghaddam, A. Antonio, C.A.T. Appiah, S.C.Y. Arabloo, J. Arab-Zozani, M. Arefi, Z. Aremu, O. Ariani, F. Arora, A. Asaad, M. Asghari, B. Awoke, N. Quintanilla, B.P.A. Ayano, G. Ayanore, M.A. Azari, S. Azarian, G. Badawi, A. Badiye, A.D. Bagli, E. Baig, A.A. Bairwa, M. Bakhtiari, A. Balachandran, A. Banach, M. Banerjee, S.K. Banik, P.C. Banstola, A. Barker-Collo, S.L. Bärnighausen, T.W. Barrero, L.H. Barzegar, A. Bayati, M. Baye, B.A. Bedi, N. Behzadifar, M. Bekuma, T.T. Belete, H. Benjet, C. Bennett, D.A. Bensenor, I.M. Berhe, K. Bhardwaj, P. Bhat, A.G. Bhattacharyya, K. Bibi, S. Bijani, A. Sayeed, M.S.B. Borges, G. Borzì, A.M. Boufous, S. Brazinova, A. Briko, N.I. Budhathoki, S.S. Car, J. Cárdenas, R. Carvalho, F. Castaldelli-Maia, J.M. Castañeda-Orjuela, C.A. Castelpietra, G. Catalá-López, F. Cerin, E. Chandan, J.S. Chanie, W.F. Chattu, S.K. Chattu, V.K. Chatziralli, I. Chaudhary, N. Cho, D.Y. Chowdhury, M.A.K. Chu, D.-T. Colquhoun, S.M. Constantin, M.-M. Costa, V.M. Damiani, G. Daryani, A. Dávila-Cervantes, C.A. Demeke, F.M. Demis, A.B. Demoz, G.T. Demsie, D.G. Derakhshani, A. Deribe, K. Desai, R. Nasab, M.D. Dias da Silva, D. Forooshani, Z.S.D. Doyle, K.E. Driscoll, T.R. Dubljanin, E. Adema, B.D. Eagan, A.W. Eftekhari, A. Ehsani-Chimeh, E. El Sayed Zaki, M. Elemineh, D.A. El-Jaafary, S.I. El-Khatib, Z. Ellingsen, C.L. Emamian, M.H. Endalew, D.A. Eskandarieh, S. Faris, P.S. Faro, A. Farzadfar, F. Fatahi, Y. Fekadu, W. Ferede, T.Y. Fereshtehnejad, S.-M. Fernandes, E. Ferrara, P. Feyissa, G.T. Filip, I. Fischer, F. Folayan, M.O. Foroutan, M. Francis, J.M. Franklin, R.C. Fukumoto, T. Geberemariyam, B.S. Gebre, A.K. Gebremedhin, K.B. Gebremeskel, G.G. Gebremichael, B. Gedefaw, G.A. Geta, B. Ghafourifard, M. Ghamari, F. Ghashghaee, A. Gholamian, A. Gill, T.K. Goulart, A.C. Grada, A. Grivna, M. Gubari, M.I.M. Guimarães, R.A. Guo, Y. Gupta, G. Haagsma, J.A. Hafezi-Nejad, N. Bidgoli, H.H. Hall, B.J. Hamadeh, R.R. Hamidi, S. Haro, J.M. Hasan, M.M. Hasanzadeh, A. Hassanipour, S. Hassankhani, H. Hassen, H.Y. Havmoeller, R. Hayat, K. Hendrie, D. Heydarpour, F. Híjar, M. Ho, H.C. Hoang, C.L. Hole, M.K. Holla, R. Hossain, N. Hosseinzadeh, M. Hostiuc, S. Hu, G. Ibitoye, S.E. Ilesanmi, O.S. Ilic, I. Ilic, M.D. Inbaraj, L.R. Indriasih, E. Irvani, S.S.N. Islam, S.M.S. Mofizul Islam, M. Ivers, R.Q. Jacobsen, K.H. Jahani, M.A. Jahanmehr, N. Jakovljevic, M. Jalilian, F. Jayaraman, S. Jayatilleke, A.U. Jha, R.P. John-Akinola, Y.O. Jonas, J.B. Joseph, N. Joukar, F. Jozwiak, J.J. Jungari, S.B. Jürisson, M. Kabir, A. Kadel, R. Kahsay, A. Kalankesh, L.R. Kalhor, R. Kamil, T.A. Kanchan, T. Kapoor, N. Karami, M. Kasaeian, A. Kassaye, H.G. Kavetskyy, T. Kebede, H.K. Keiyoro, P.N. Kelbore, A.G. Kelkay, B. Khader, Y.S. Khafaie, M.A. Khalid, N. Khalil, I.A. Khalilov, R. Khammarnia, M. Khan, E.A. Khan, M. Khanna, T. Khazaie, H. Shadmani, F.K. Khundkar, R. Kiirithio, D.N. Kim, Y.-E. Kim, D. Kim, Y.J. Kisa, A. Kisa, S. Komaki, H. Kondlahalli, S.K.M. Korshunov, V.A. Koyanagi, A. Kraemer, M.U.G. Krishan, K. Bicer, B.K. Kugbey, N. Kumar, V. Kumar, N. Anil Kumar, G. Kumar, M. Kumaresh, G. Kurmi, O.P. Kuti, O. Vecchia, C.L. Lami, F.H. Lamichhane, P. Lang, J.J. Lansingh, V.C. Laryea, D.O. Lasrado, S. Latifi, A. Lauriola, P. Leasher, J.L. Lee, S.W.H. Lenjebo, T.L. Levi, M. Li, S. Linn, S. Liu, X. Lopez, A.D. Lotufo, P.A. Lunevicius, R. Lyons, R.A. Madadin, M. El Razek, M.M.A. Mahotra, N.B. Majdan, M. Majeed, A. Malagon-Rojas, J.N. Maled, V. Malekzadeh, R. Malta, D.C. Manafi, N. Manafi, A. Manda, A.-L. Manjunatha, N. Mansour-Ghanaei, F. Mansouri, B. Mansournia, M.A. Maravilla, J.C. March, L.M. Mason-Jones, A.J. Masoumi, S.Z. Massenburg, B.B. Maulik, P.K. Meles, G.G. Melese, A. Melketsedik, Z.A. Memiah, P.T.N. Mendoza, W. Menezes, R.G. Mengesha, M.B. Mengesha, M.M. Meretoja, T.J. Meretoja, A. Merie, H.E. Mestrovic, T. Miazgowski, B. Miazgowski, T. Miller, T.R. Mini, G.K. Mirica, A. Mirrakhimov, E.M. Mirzaei-Alavijeh, M. Mithra, P. Moazen, B. Moghadaszadeh, M. Mohamadi, E. Mohammad, Y. Mohammad, K.A. Darwesh, A.M. Mezerji, N.M.G. Mohammadian-Hafshejani, A. Mohammadoo-Khorasani, M. Mohammadpourhodki, R. Mohammed, S. Mohammed, J.A. Mohebi, F. Molokhia, M. Monasta, L. Moodley, Y. Moosazadeh, M. Moradi, M. Moradi, G. Moradi-Lakeh, M. Moradpour, F. Morawska, L. Velásquez, I.M. Morisaki, N. Morrison, S.D. Mossie, T.B. Muluneh, A.G. Murthy, S. Musa, K.I. Mustafa, G. Nabhan, A.F. Nagarajan, A.J. Naik, G. Naimzada, M.D. Najafi, F. Nangia, V. Nascimento, B.R. Naserbakht, M. Nayak, V. Ndwandwe, D.E. Negoi, I. Ngunjiri, J.W. Nguyen, C.T. Nguyen, H.L.T. Nikbakhsh, R. Ningrum, D.N.A. Nnaji, C.A. Nyasulu, P.S. Ogbo, F.A. Oghenetega, O.B. Oh, I.-H. Okunga, E.W. Olagunju, A.T. Olagunju, T.O. Bali, A.O. Onwujekwe, O.E. Asante, K.O. Orpana, H.M. Ota, E. Otstavnov, N. Otstavnov, S.S. Mahesh, P.A. Padubidri, J.R. Pakhale, S. Pakshir, K. Panda-Jonas, S. Park, E.-K. Patel, S.K. Pathak, A. Pati, S. Patton, G.C. Paulos, K. Peden, A.E. Pepito, V.C.F. Pereira, J. Pham, H.Q. Phillips, M.R. Pinheiro, M. Polibin, R.V. Polinder, S. Poustchi, H. Prakash, S. Pribadi, D.R.A. Puri, P. Syed, Z.Q. Rabiee, M. Rabiee, N. Radfar, A. Rafay, A. Rafiee, A. Rafiei, A. Rahim, F. Rahimi, S. Rahimi-Movaghar, V. Rahman, M.A. Rajabpour-Sanati, A. Rajati, F. Rakovac, I. Ranganathan, K. Rao, S.J. Rashedi, V. Rastogi, P. Rathi, P. Rawaf, S. Rawal, L. Rawassizadeh, R. Renjith, V. Renzaho, A.M.N. Resnikoff, S. Rezapour, A. Ribeiro, A.I. Rickard, J. González, C.M.R. Ronfani, L. Roshandel, G. Saad, A.M. Sabde, Y.D. Sabour, S. Saddik, B. Safari, S. Safari-Faramani, R. Safarpour, H. Safdarian, M. Mohammad Sajadi, S. Salamati, P. Salehi, F. Zahabi, S.S. Rashad Salem, M.R. Salem, H. Salman, O. Salz, I. Samy, A.M. Sanabria, J. Riera, L.S. Santric Milicevic, M.M. Sarker, A.R. Sarveazad, A. Sathian, B. Sawhney, M. Sawyer, S.M. Saxena, S. Sayyah, M. Schwebel, D.C. Seedat, S. Senthilkumaran, S. Sepanlou, S.G. Seyedmousavi, S. Sha, F. Shaahmadi, F. Shahabi, S. Shaikh, M.A. Shams-Beyranvand, M. Shamsizadeh, M. Sharif-Alhoseini, M. Sharifi, H. Sheikh, A. Shigematsu, M. Shin, J.I. Shiri, R. Siabani, S. Sigfusdottir, I.D. Singh, P.K. Singh, J.A. Sinha, D.N. Smarandache, C.-G. Smith, E.U.R. Soheili, A. Soleymani, B. Soltanian, A.R. Soriano, J.B. Sorrie, M.B. Soyiri, I.N. Stein, D.J. Stokes, M.A. Mu'awiyyah, B.S. Suleria, H.A.R. Sykes, B.L. Tabarés-Seisdedos, R. Tabb, K.M. Taddele, B.W. Tadesse, D.B. Tamiru, A.T. Tarigan, I.U. Tefera, Y.M. Tehrani-Banihashemi, A. Tekle, M.G. Tekulu, G.H. Tesema, A.K. Tesfay, B.E. Thapar, R. Tilahune, A.B. Tlaye, K.G. Tohidinik, H.R. Topor-Madry, R. Tran, B.X. Tran, K.B. Tripathy, J.P. Tsai, A.C. Car, L.T. Ullah, S. Ullah, I. Umar, M. Unnikrishnan, B. Upadhyay, E. Uthman, O.A. Valdez, P.R. Vasankari, T.J. Venketasubramanian, N. Violante, F.S. Vlassov, V. Waheed, Y. Weldesamuel, G.T. Werdecker, A. Wiangkham, T. Wolde, H.F. Woldeyes, D.H. Wondafrash, D.Z. Wondmeneh, T.G. Wondmieneh, A.B. Wu, A.-M. Yadav, R. Yadollahpour, A. Yano, Y. Yaya, S. Yazdi-Feyzabadi, V. Yip, P. Yisma, E. Yonemoto, N. Yoon, S.-J. Youm, Y. Younis, M.Z. Yousefi, Z. Yu, Y. Yu, C. Yusefzadeh, H. Moghadam, T.Z. Zaidi, Z. Zaman, S.B. Zamani, M. Zamanian, M. Zandian, H. Zarei, A. Zare, F. Zhang, Z.-J. Zhang, Y. Zodpey, S. Dandona, L. Dandona, R. Degenhardt, L. Dharmaratne, S.D. Hay, S.I. Mokdad, A.H. Reiner, R.C., Jr. Sartorius, B. Vos, T.
Abstract: Background Past research in population health trends has shown that injuries form a substantial burden of population health loss. Regular updates to injury burden assessments are critical. We report Global Burden of Disease (GBD) 2017 Study estimates on morbidity and mortality for all injuries. methods We reviewed results for injuries from the GBD 2017 study. GBD 2017 measured injury-specific mortality and years of life lost (YLLs) using the Cause of Death Ensemble model. To measure non-fatal injuries, GBD 2017 modelled injury-specific incidence and converted this to prevalence and years lived with disability (YLDs). YLLs and YLDs were summed to calculate disability-adjusted life years (DALYs). Findings In 1990, there were 4 260 493 (4 085 700 to 4 396 138) injury deaths, which increased to 4 484 722 (4 332 010 to 4 585 554) deaths in 2017, while age-standardised mortality decreased from 1079 (1073 to 1086) to 738 (730 to 745) per 100 000. In 1990, there were 354 064 302 (95% uncertainty interval: 338 174 876 to 371 610 802) new cases of injury globally, which increased to 520 710 288 (493 430 247 to 547 988 635) new cases in 2017. During this time, age-standardised incidence decreased non-significantly from 6824 (6534 to 7147) to 6763 (6412 to 7118) per 100 000. Between 1990 and 2017, age-standardised DALYs decreased from 4947 (4655 to 5233) per 100 000 to 3267 (3058 to 3505). Interpretation Injuries are an important cause of health loss globally, though mortality has declined between 1990 and 2017. Future research in injury burden should focus on prevention in high-burden populations, improving data collection and ensuring access to medical care. © Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ.
Published: 2020

4. Mapping child growth failure across low- and middle-income countries.

Author: Faro A., Renzaho A.M.N., Rios-Gonzalez C., Roever L., Ross J.M., Rostami A., Sadat N., Safari Y., Safdarian M., Sahebkar A., Salam N., Salamati P., Salimi Y., Salimzadeh H., Samy A.M., Sartorius B., Sathian B., Schipp M.F., Schwebel D.C., Senbeta A.M., Sepanlou S.G., Shaikh M.A., Levy T.S., Shamsi M., Sharafi K., Sharma R., Sheikh A., Shil A., Silva D.A.S., Singh J.A., Sinha D.N., Soofi M., Sudaryanto A., Sufiyan M.B., Tabares-Seisdedos R., Tadesse B.T., Temsah M.-H., Terkawi A.S., Tessema Z.T., Thorne-Lyman A.L., Tovani-Palone M.R., Tran B.X., Tran K.B., Ullah I., Uthman O.A., Vaezghasemi M., Vaezi A., Valdez P.R., Vanderheide J., Veisani Y., Violante F.S., Vlassov V., Vu G.T., Vu L.G., Waheed Y., Walson J.L., Wang Y., Wang Y.-P., Wangia E.N., Werdecker A., Xu G., Yamada T., Yisma E., Yonemoto N., Younis M.Z., Yousefifard M., Yu C., Zaman S.B., Zamani M., Zhang Y., Kassebaum N.J., Hay S.I., Hamidi S., Kinyoki D.K., Osgood-Zimmerman A.E., Pickering B.V., Schaeffer L.E., Marczak L.B., Lazzar-Atwood A., Collison M.L., Henry N.J., Abebe Z., Adamu A.A., Adekanmbi V., Ahmadi K., Ajumobi O., Al-Eyadhy A., Al-Raddadi R.M., Alahdab F., Alijanzadeh M., Alipour V., Altirkawi K., Amini S., Andrei C.L., Antonio C.A.T., Arabloo J., Aremu O., Asadi-Aliabadi M., Atique S., Ausloos M., Avila M., Awasthi A., Quintanilla B.P.A., Azari S., Badawi A., Barnighausen T.W., Bassat Q., Baye K., Bedi N., Bekele B.B., Bell M.L., Bhattacharjee N.V., Bhattacharyya K., Bhattarai S., Bhutta Z.A., Biadgo B., Bikbov B., Briko A.N., Britton G., Burstein R., Butt Z.A., Car J., Castaneda-Orjuela C.A., Castro F., Cerin E., Chipeta M.G., Chu D.-T., Cork M.A., Cromwell E.A., Cuevas-Nasu L., Dandona L., Dandona R., Daoud F., Gupta R.D., Weaver N.D., Leo D.D., Neve J.-W.D., Deribe K., Desalegn B.B., Deshpande A., Desta M., Diaz D., Dinberu M.T., Doku D.T., Dubey M., Duraes A.R., Dwyer-Lindgren L., Earl L., Effiong A., Zaki M.E.S., Tantawi M.E., El-Khatib Z., Eshrati B., Fareed M., Fereshtehnejad S.-M., Filip I., Fischer F., Foigt N.A., Folayan M.O., Fukumoto T., Gebrehiwot T.T., Gezae K.E., Ghajar A., Gill P.S., Gona P.N., Gopalani S.V., Grada A., Guo Y., Haj-Mirzaian A., Hall J.B., Henok A., Prado B.H., Herrero M., Herteliu C., Hoang C.L., Hole M.K., Hossain N., Hosseinzadeh M., Hu G., Islam S.M.S., Jakovljevic M., Jha R.P., Jonas J.B., Jozwiak J.J., Kahsay A., Kanchan T., Karami M., Kasaeian A., Khader Y.S., Khan E.A., Khater M.M., Kim Y.J., Kimokoti R.W., Kisa A., Kochhar S., Kosen S., Koyanagi A., Krishan K., Defo B.K., Kumar G.A., Kumar M., Lad S.D., Lami F.H., Lee P.H., Levine A.J., Li S., Linn S., Lodha R., El Razek H.M.A., Abd El Razek M.M., Majdan M., Majeed A., Malekzadeh R., Malta D.C., Mamun A.A., Mansournia M.A., Martins-Melo F.R., Masaka A., Massenburg B.B., Mayala B.K., Mejia-Rodriguez F., Melku M., Mendoza W., Mensah G.A., Miazgowski T., Miller T.R., Mini G.K., Mirrakhimov E.M., Moazen B., Darwesh A.M., Mohammed S., Mohebi F., Mokdad A.H., Moodley Y., Moradi G., Moradi-Lakeh M., Moraga P., Morrison S.D., Mosser J.F., Mousavi S.M., Mueller U.O., Murray C.J.L., Mustafa G., Naderi M., Naghavi M., Najafi F., Nangia V., Ndwandwe D.E., Negoi I., Ngunjiri J.W., Nguyen H.L.T., Nguyen L.H., Nguyen S.H., Nie J., Nnaji C.A., Noubiap J.J., Shiadeh M.N., Nyasulu P.S., Ogbo F.A., Olagunju A.T., Olusanya B.O., Olusanya J.O., Ortiz-Panozo E., Otstavnov S.S., P. A M., Pana A., Pandey A., Pati S., Patil S.T., Patton G.C., Perico N., Pigott D.M., Pirsaheb M., Piwoz E.G., Postma M.J., Pourshams A., Prakash S., Quintana H., Radfar A., Rafiei A., Rahimi-Movaghar V., Rai R.K., Rajati F., Rawaf D.L., Rawaf S., Rawat R., Remuzzi G., Faro A., Renzaho A.M.N., Rios-Gonzalez C., Roever L., Ross J.M., Rostami A., Sadat N., Safari Y., Safdarian M., Sahebkar A., Salam N., Salamati P., Salimi Y., Salimzadeh H., Samy A.M., Sartorius B., Sathian B., Schipp M.F., Schwebel D.C., Senbeta A.M., Sepanlou S.G., Shaikh M.A., Levy T.S., Shamsi M., Sharafi K., Sharma R., Sheikh A., Shil A., Silva D.A.S., Singh J.A., Sinha D.N., Soofi M., Sudaryanto A., Sufiyan M.B., Tabares-Seisdedos R., Tadesse B.T., Temsah M.-H., Terkawi A.S., Tessema Z.T., Thorne-Lyman A.L., Tovani-Palone M.R., Tran B.X., Tran K.B., Ullah I., Uthman O.A., Vaezghasemi M., Vaezi A., Valdez P.R., Vanderheide J., Veisani Y., Violante F.S., Vlassov V., Vu G.T., Vu L.G., Waheed Y., Walson J.L., Wang Y., Wang Y.-P., Wangia E.N., Werdecker A., Xu G., Yamada T., Yisma E., Yonemoto N., Younis M.Z., Yousefifard M., Yu C., Zaman S.B., Zamani M., Zhang Y., Kassebaum N.J., Hay S.I., Hamidi S., Kinyoki D.K., Osgood-Zimmerman A.E., Pickering B.V., Schaeffer L.E., Marczak L.B., Lazzar-Atwood A., Collison M.L., Henry N.J., Abebe Z., Adamu A.A., Adekanmbi V., Ahmadi K., Ajumobi O., Al-Eyadhy A., Al-Raddadi R.M., Alahdab F., Alijanzadeh M., Alipour V., Altirkawi K., Amini S., Andrei C.L., Antonio C.A.T., Arabloo J., Aremu O., Asadi-Aliabadi M., Atique S., Ausloos M., Avila M., Awasthi A., Quintanilla B.P.A., Azari S., Badawi A., Barnighausen T.W., Bassat Q., Baye K., Bedi N., Bekele B.B., Bell M.L., Bhattacharjee N.V., Bhattacharyya K., Bhattarai S., Bhutta Z.A., Biadgo B., Bikbov B., Briko A.N., Britton G., Burstein R., Butt Z.A., Car J., Castaneda-Orjuela C.A., Castro F., Cerin E., Chipeta M.G., Chu D.-T., Cork M.A., Cromwell E.A., Cuevas-Nasu L., Dandona L., Dandona R., Daoud F., Gupta R.D., Weaver N.D., Leo D.D., Neve J.-W.D., Deribe K., Desalegn B.B., Deshpande A., Desta M., Diaz D., Dinberu M.T., Doku D.T., Dubey M., Duraes A.R., Dwyer-Lindgren L., Earl L., Effiong A., Zaki M.E.S., Tantawi M.E., El-Khatib Z., Eshrati B., Fareed M., Fereshtehnejad S.-M., Filip I., Fischer F., Foigt N.A., Folayan M.O., Fukumoto T., Gebrehiwot T.T., Gezae K.E., Ghajar A., Gill P.S., Gona P.N., Gopalani S.V., Grada A., Guo Y., Haj-Mirzaian A., Hall J.B., Henok A., Prado B.H., Herrero M., Herteliu C., Hoang C.L., Hole M.K., Hossain N., Hosseinzadeh M., Hu G., Islam S.M.S., Jakovljevic M., Jha R.P., Jonas J.B., Jozwiak J.J., Kahsay A., Kanchan T., Karami M., Kasaeian A., Khader Y.S., Khan E.A., Khater M.M., Kim Y.J., Kimokoti R.W., Kisa A., Kochhar S., Kosen S., Koyanagi A., Krishan K., Defo B.K., Kumar G.A., Kumar M., Lad S.D., Lami F.H., Lee P.H., Levine A.J., Li S., Linn S., Lodha R., El Razek H.M.A., Abd El Razek M.M., Majdan M., Majeed A., Malekzadeh R., Malta D.C., Mamun A.A., Mansournia M.A., Martins-Melo F.R., Masaka A., Massenburg B.B., Mayala B.K., Mejia-Rodriguez F., Melku M., Mendoza W., Mensah G.A., Miazgowski T., Miller T.R., Mini G.K., Mirrakhimov E.M., Moazen B., Darwesh A.M., Mohammed S., Mohebi F., Mokdad A.H., Moodley Y., Moradi G., Moradi-Lakeh M., Moraga P., Morrison S.D., Mosser J.F., Mousavi S.M., Mueller U.O., Murray C.J.L., Mustafa G., Naderi M., Naghavi M., Najafi F., Nangia V., Ndwandwe D.E., Negoi I., Ngunjiri J.W., Nguyen H.L.T., Nguyen L.H., Nguyen S.H., Nie J., Nnaji C.A., Noubiap J.J., Shiadeh M.N., Nyasulu P.S., Ogbo F.A., Olagunju A.T., Olusanya B.O., Olusanya J.O., Ortiz-Panozo E., Otstavnov S.S., P. A M., Pana A., Pandey A., Pati S., Patil S.T., Patton G.C., Perico N., Pigott D.M., Pirsaheb M., Piwoz E.G., Postma M.J., Pourshams A., Prakash S., Quintana H., Radfar A., Rafiei A., Rahimi-Movaghar V., Rai R.K., Rajati F., Rawaf D.L., Rawaf S., Rawat R., and Remuzzi G.
Abstract: Childhood malnutrition is associated with high morbidity and mortality globally1. Undernourished children are more likely to experience cognitive, physical, and metabolic developmental impairments that can lead to later cardiovascular disease, reduced intellectual ability and school attainment, and reduced economic productivity in adulthood2. Child growth failure (CGF), expressed as stunting, wasting, and underweight in children under five years of age (0-59 months), is a specific subset of undernutrition characterized by insufficient height or weight against age-specific growth reference standards3-5. The prevalence of stunting, wasting, or underweight in children under five is the proportion of children with a height-for-age, weight-for-height, or weight-for-age z-score, respectively, that is more than two standard deviations below the World Health Organization's median growth reference standards for a healthy population6. Subnational estimates of CGF report substantial heterogeneity within countries, but are available primarily at the first administrative level (for example, states or provinces)7; the uneven geographical distribution of CGF has motivated further calls for assessments that can match the local scale of many public health programmes8. Building from our previous work mapping CGF in Africa9, here we provide the first, to our knowledge, mapped high-spatial-resolution estimates of CGF indicators from 2000 to 2017 across 105 low- and middle-income countries (LMICs), where 99% of affected children live1, aggregated to policy-relevant first and second (for example, districts or counties) administrative-level units and national levels. Despite remarkable declines over the study period, many LMICs remain far from the ambitious World Health Organization Global Nutrition Targets to reduce stunting by 40% and wasting to less than 5% by 2025. Large disparities in prevalence and progress exist across and within countries; our maps identify high-prevalence areas e
Published: 2020

5. Mapping child growth failure across low- and middle-income countries

Author: Kinyoki, D.K. (Damaris K.), Osgood-Zimmerman, A.E. (Aaron E.), Pickering, B.V. (Brandon V.), Schaeffer, L.E. (Lauren E.), Marczak, L.B. (Laurie B.), Lazzar-Atwood, A. (Alice), Collison, M.L. (Michael L.), Henry, N.J. (Nathaniel J.), Abebe, Z. (Zegeye), Adamu, A.A. (Abdu A.), Adekanmbi, V. (Victor), Ahmadi, K. (Keivan), Ajumobi, O. (Olufemi), Al-Eyadhy, A. (Ayman), Al-Raddadi, R.M. (Rajaa M.), Alahdab, F. (Fares), Alijanzadeh, M. (Mehran), Alipour, V. (Vahid), Altirkawi, K. (Khalid), Amini, S. (Saeed), Andrei, C.L. (Catalina Liliana), Antonio, C.A.T. (Carl Abelardo T), Arabloo, J. (Jalal), Aremu, O. (Olatunde), Asadi-Aliabadi, M. (Mehran), Atique, S. (Suleman), Ausloos, M. (Marcel), Avila, M. (Marco), Awasthi, A. (Ashish), Quintanilla, B.P.A. (Beatriz Paulina Ayala), Azari, S. (Samad), Badawi, A. (Alaa), Bärnighausen, T. (Till), Bassat, Q. (Quique), Baye, K. (Kaleab), Bedi, N. (Neeraj), Bekele, B.B. (Bayu Begashaw), Bell, M.L. (Michelle L.), Bhattacharjee, N.V. (Natalia V.), Bhattacharyya, K. (Krittika), Bhattarai, S. (Suraj), Bhutta, Z.A. (Zulfiqar A), Biadgo, B. (Belete), Bikbov, B. (Boris), Briko, A.N. (Andrey Nikolaevich), Britton, G. (Gabrielle), Burstein, D. (David), Butt, Z.A. (Zahid A.), Car, J. (Josip), Castañeda-Orjuela, C.A. (Carlos A), Castro, F. (Franz), Cerin, E. (Ester), Chipeta, M.G. (Michael G.), Chu, D.-T. (Dinh-Toi), Cork, M.A. (Michael A.), Cromwell, E.A. (Elizabeth A.), Cuevas-Nasu, L. (Lucía), Dandona, L. (Lalit), Dandona, R. (Rakhi), Daoud, F. (Farah), Gupta, R.D. (Rajat Das), Weaver, N.D. (Nicole Davis), Leo, D.D. (Diego De), Neve, J.-W.D. (Jan-Walter De), Deribe, K. (Kebede), Desalegn, B.B. (Beruk Berhanu), Deshpande, A. (Aniruddha), Desta, M. (Melaku), Diaz, D. (Daniel), Dinberu, M.T. (Mesfin Tadese), Doku, D.T. (David Teye), Dubey, M. (Manisha), Durães, A.R. (Andre R.), Dwyer-Lindgren, L.A. (Laura), Earl, L. (Lucas), Effiong, A. (Andem), Zaki, M.E.S. (Maysaa El Sayed), Tantawi, M.E. (Maha El), El-Khatib, Z. (Ziad), Eshrati, B. (Babak), Fareed, M. (Mohammad), Faro, A. (Andre), Fereshtehnejad, S.-M. (Seyed-Mohammad), Filip, I. (Irina), Fischer, F. (Florian), Foigt, N.A. (Nataliya A.), Folayan, M.O. (Morenike Oluwatoyin), Fukumoto, T. (Takeshi), Gebrehiwot, T.T. (Tsegaye Tewelde), Gezae, K.E. (Kebede Embaye), Ghajar, A. (Alireza), Gill, P.S. (Paramjit Singh), Gona, P.N. (Philimon N.), Gopalani, S.V. (Sameer Vali), Grada, A. (Ayman), Guo, Y. (Yuming), Haj-Mirzaian, A. (Arvin), Haj-Mirzaian, A. (Arya), Hall, J.B. (Jason B.), Hamidi, S. (Samer), Henok, A. (Andualem), Prado, B.H. (Bernardo Hernández), Herrero, M. (Mario), Herteliu, C. (Claudiu), Hoang, C.L. (Chi Linh), Hole, M.K. (Michael K.), Hossain, N. (Naznin), Hosseinzadeh, M. (Mehdi), Hu, G. (Guoqing), Islam, S.M.S. (Sheikh Mohammed Shariful), Jakovljevic, M. (Mihajlo), Jha, R.P. (Ravi Prakash), Jonas, J.B. (Jost B.), Jozwiak, J.J. (Jacek Jerzy), Kahsay, A. (Amaha), Kanchan, T. (Tanuj), Karami, M. (Manoochehr), Kasaeian, A. (Amir), Khader, Y.S. (Yousef Saleh), Khan, E.A. (Ejaz Ahmad), Khater, M.M. (Mona M.), Kim, Y.J. (Yun Jin), Kimokoti, R.W. (Ruth W.), Kisa, A. (Adnan), Kochhar, S. (Sonali), Kosen, S. (Soewarta), Koyanagi, A. (Ai), Krishan, K. (Kewal), Defo, B.K. (Barthelemy Kuate), Kumar, G.A. (G. Anil), Kumar, M. (Manasi), Lad, S.D. (Sheetal D.), Lami, F.H. (Faris Hasan), Lee, P.H. (Paul H.), Levine, A.J. (Aubrey J.), Li, S. (Shanshan), Linn, S. (Shai), Lodha, R. (Rakesh), El Razek, H.M.A. (Hassan Magdy Abd), Abd El Razek, M.M. (Muhammed Magdy), Hosgood, H.D. (H Dean), Majeed, A. (Azeem), Malekzadeh, R. (Reza), Malta, D.C. (Deborah Carvalho), Mamun, A.A. (Abdullah A.), Mansournia, M.A. (Mohammad Ali), Martins-Melo, F.R. (Francisco Rogerlândio), Masaka, A. (Anthony), Massenburg, B.B. (Benjamin Ballard), Mayala, B.K. (Benjamin K.), Mejia-Rodriguez, F. (Fabiola), Melku, M. (Mulugeta), Mendoza, W. (Walter), Mensah, G.A. (George A.), Miazgowski, T. (T.), Miller, T.R. (Ted R.), Mini, G.K. (G. K.), Mirrakhimov, E.M. (Erkin M.), Moazen, B. (Babak), Darwesh, A.M. (Aso Mohammad), Mohammed, S. (Shafiu), Mohebi, F. (Farnam), Mokdad, A.H. (Ali H.), Moodley, Y. (Yoshan), Moradi, G. (Ghobad), Moradi-Lakeh, M. (Maziar), Moraga, P. (Paula), Morrison, S.D. (Shane Douglas), Mosser, J.F. (Jonathan F.), Mousavi, S.M. (Seyyed Meysam), Mueller, U.O. (Ulrich Otto), Murray, C.J.L. (Christopher J. L.), Mustafa, G. (Ghulam), Naderi, M. (Mehdi), Naghavi, M. (Morteza), Najafi, F. (Farid), Nangia, V. (Vinay), Ndwandwe, D.E. (Duduzile Edith), Negoi, I. (Ionut), Ngunjiri, J.W. (Josephine W.), Nguyen, H.L.T. (Huong Lan Thi), Nguyen, L.H. (Long Hoang), Nguyen, S.H. (Son Hoang), Nie, J. (Jing), Nnaji, C.A. (Chukwudi A.), Noubiap, J.J. (Jean Jacques), Shiadeh, M.N. (Malihe Nourollahpour), Nyasulu, P.S. (Peter S.), Ogbo, F.A. (Felix Akpojene), Olagunju, A.T. (Andrew T.), Olusanya, B.O. (Bolajoko O), Olusanya, J.O. (Jacob Olusegun), Ortiz-Panozo, E. (Eduardo), Otstavnov, S.S. (Stanislav S.), P. A, M. (Mahesh), Pana, A. (Adrian), Pandey, A. (Anamika), Pati, S. (Sanghamitra), Patil, S.T. (Snehal T.), Patton, G.C. (George C.), Perico, N. (Norberto), Pigott, D.M. (David M.), Pirsaheb, M. (Meghdad), Piwoz, E.G. (Ellen G.), Postma, M.J. (Maarten), Pourshams, A. (Akram), Prakash, S. (Swayam), Quintana, H. (Hedley), Radfar, A. (Amir), Rafiei, A. (Alireza), Rahimi-Movaghar, V. (Vafa), Rai, R.K. (Rajesh Kumar), Rajati, F. (Fatemeh), Rawaf, D.L. (David Laith), Rawaf, S. (Salman), Rawat, R. (Rahul), Remuzzi, G. (Giuseppe), Renzaho, A.M.N. (Andre M. N.), Rios-González, C. (Carlos), Roever, L. (Leonardo), Ross, J.M. (Jennifer M.), Rostami, A. (Ali), Sadat, N. (Nafis), Safari, Y. (Yahya), Safdarian, M. (Mahdi), Sahebkar, A. (Amirhossein), Salam, N. (Nasir), Salamati, P. (Payman), Salimi, Y. (Yahya), Salimzadeh, H. (Hamideh), Samy, A.M. (Abdallah M.), Sartorius, B. (Benn), Sathian, B. (Brijesh), Schipp, M.F. (Megan F.), Schwebel, D.C. (David C), Senbeta, A.M. (Anbissa Muleta), Sepanlou, S.G. (Sadaf G), Shaikh, M.A. (Masood Ali), Levy, T.S. (Teresa Shamah), Shamsi, M. (Mohammadbagher), Sharafi, K. (Kiomars), Sharma, R. (Rajesh), Sheikh, A. (Aziz), Shil, A. (Apurba), Silva, D.A.S. (Diego Augusto Santos), Singh, J.A. (Jasvinder A.), Sinha, D.N. (Dhirendra Narain), Soofi, M. (Moslem), Sudaryanto, A. (Agus), Sufiyan, M.B. (Muawiyyah Babale), Tabarés-Seisdedos, R. (Rafael), Tadesse, B.T. (Birkneh Tilahun), Temsah, M.-H. (Mohamad-Hani), Terkawi, A.S. (Abdullah Sulieman), Tessema, Z.T. (Zemenu Tadesse), Thorne-Lyman, A.L. (Andrew L.), Tovani-Palone, M.R. (Marcos Roberto), Tran, B.X. (Bach Xuan), Tran, K.B. (Khanh Bao), Ullah, I. (Irfan), Uthman, O.A. (Olalekan A.), Vaezghasemi, M. (Masoud), Vaezi, A. (Afsane), Valdez, P.R. (Pascual R.), Vanderheide, J. (John), Veisani, Y. (Yousef), Violante, F.S. (Francesco S), Vlassov, V. (Vasily), Vu, G.T. (Giang Thu), Vu, L.G. (Linh Gia), Waheed, Y. (Yasir), Walson, J.L. (Judd L.), Wang, Y. (Yafeng), Wang, Y.-P. (Yuan-Pang), Wangia, E.N. (Elizabeth N.), Werdecker, A. (Andrea), Xu, G. (Gelin), Yamada, T. (Tomohide), Yisma, E. (Engida), Yonemoto, N. (Naohiro), Younis, M.Z. (Mustafa Z.), Yousefifard, M. (Mahmoud), Yu, C. (Chuanhua), Zaman, S.B. (Sojib Bin), Zamani, M. (Mohammad), Zhang, Y. (Yunquan), Kassebaum, N.J. (Nicholas J.), Hay, S.I. (Simon), Kinyoki, D.K. (Damaris K.), Osgood-Zimmerman, A.E. (Aaron E.), Pickering, B.V. (Brandon V.), Schaeffer, L.E. (Lauren E.), Marczak, L.B. (Laurie B.), Lazzar-Atwood, A. (Alice), Collison, M.L. (Michael L.), Henry, N.J. (Nathaniel J.), Abebe, Z. (Zegeye), Adamu, A.A. (Abdu A.), Adekanmbi, V. (Victor), Ahmadi, K. (Keivan), Ajumobi, O. (Olufemi), Al-Eyadhy, A. (Ayman), Al-Raddadi, R.M. (Rajaa M.), Alahdab, F. (Fares), Alijanzadeh, M. (Mehran), Alipour, V. (Vahid), Altirkawi, K. (Khalid), Amini, S. (Saeed), Andrei, C.L. (Catalina Liliana), Antonio, C.A.T. (Carl Abelardo T), Arabloo, J. (Jalal), Aremu, O. (Olatunde), Asadi-Aliabadi, M. (Mehran), Atique, S. (Suleman), Ausloos, M. (Marcel), Avila, M. (Marco), Awasthi, A. (Ashish), Quintanilla, B.P.A. (Beatriz Paulina Ayala), Azari, S. (Samad), Badawi, A. (Alaa), Bärnighausen, T. (Till), Bassat, Q. (Quique), Baye, K. (Kaleab), Bedi, N. (Neeraj), Bekele, B.B. (Bayu Begashaw), Bell, M.L. (Michelle L.), Bhattacharjee, N.V. (Natalia V.), Bhattacharyya, K. (Krittika), Bhattarai, S. (Suraj), Bhutta, Z.A. (Zulfiqar A), Biadgo, B. (Belete), Bikbov, B. (Boris), Briko, A.N. (Andrey Nikolaevich), Britton, G. (Gabrielle), Burstein, D. (David), Butt, Z.A. (Zahid A.), Car, J. (Josip), Castañeda-Orjuela, C.A. (Carlos A), Castro, F. (Franz), Cerin, E. (Ester), Chipeta, M.G. (Michael G.), Chu, D.-T. (Dinh-Toi), Cork, M.A. (Michael A.), Cromwell, E.A. (Elizabeth A.), Cuevas-Nasu, L. (Lucía), Dandona, L. (Lalit), Dandona, R. (Rakhi), Daoud, F. (Farah), Gupta, R.D. (Rajat Das), Weaver, N.D. (Nicole Davis), Leo, D.D. (Diego De), Neve, J.-W.D. (Jan-Walter De), Deribe, K. (Kebede), Desalegn, B.B. (Beruk Berhanu), Deshpande, A. (Aniruddha), Desta, M. (Melaku), Diaz, D. (Daniel), Dinberu, M.T. (Mesfin Tadese), Doku, D.T. (David Teye), Dubey, M. (Manisha), Durães, A.R. (Andre R.), Dwyer-Lindgren, L.A. (Laura), Earl, L. (Lucas), Effiong, A. (Andem), Zaki, M.E.S. (Maysaa El Sayed), Tantawi, M.E. (Maha El), El-Khatib, Z. (Ziad), Eshrati, B. (Babak), Fareed, M. (Mohammad), Faro, A. (Andre), Fereshtehnejad, S.-M. (Seyed-Mohammad), Filip, I. (Irina), Fischer, F. (Florian), Foigt, N.A. (Nataliya A.), Folayan, M.O. (Morenike Oluwatoyin), Fukumoto, T. (Takeshi), Gebrehiwot, T.T. (Tsegaye Tewelde), Gezae, K.E. (Kebede Embaye), Ghajar, A. (Alireza), Gill, P.S. (Paramjit Singh), Gona, P.N. (Philimon N.), Gopalani, S.V. (Sameer Vali), Grada, A. (Ayman), Guo, Y. (Yuming), Haj-Mirzaian, A. (Arvin), Haj-Mirzaian, A. (Arya), Hall, J.B. (Jason B.), Hamidi, S. (Samer), Henok, A. (Andualem), Prado, B.H. (Bernardo Hernández), Herrero, M. (Mario), Herteliu, C. (Claudiu), Hoang, C.L. (Chi Linh), Hole, M.K. (Michael K.), Hossain, N. (Naznin), Hosseinzadeh, M. (Mehdi), Hu, G. (Guoqing), Islam, S.M.S. (Sheikh Mohammed Shariful), Jakovljevic, M. (Mihajlo), Jha, R.P. (Ravi Prakash), Jonas, J.B. (Jost B.), Jozwiak, J.J. (Jacek Jerzy), Kahsay, A. (Amaha), Kanchan, T. (Tanuj), Karami, M. (Manoochehr), Kasaeian, A. (Amir), Khader, Y.S. (Yousef Saleh), Khan, E.A. (Ejaz Ahmad), Khater, M.M. (Mona M.), Kim, Y.J. (Yun Jin), Kimokoti, R.W. (Ruth W.), Kisa, A. (Adnan), Kochhar, S. (Sonali), Kosen, S. (Soewarta), Koyanagi, A. (Ai), Krishan, K. (Kewal), Defo, B.K. (Barthelemy Kuate), Kumar, G.A. (G. Anil), Kumar, M. (Manasi), Lad, S.D. (Sheetal D.), Lami, F.H. (Faris Hasan), Lee, P.H. (Paul H.), Levine, A.J. (Aubrey J.), Li, S. (Shanshan), Linn, S. (Shai), Lodha, R. (Rakesh), El Razek, H.M.A. (Hassan Magdy Abd), Abd El Razek, M.M. (Muhammed Magdy), Hosgood, H.D. (H Dean), Majeed, A. (Azeem), Malekzadeh, R. (Reza), Malta, D.C. (Deborah Carvalho), Mamun, A.A. (Abdullah A.), Mansournia, M.A. (Mohammad Ali), Martins-Melo, F.R. (Francisco Rogerlândio), Masaka, A. (Anthony), Massenburg, B.B. (Benjamin Ballard), Mayala, B.K. (Benjamin K.), Mejia-Rodriguez, F. (Fabiola), Melku, M. (Mulugeta), Mendoza, W. (Walter), Mensah, G.A. (George A.), Miazgowski, T. (T.), Miller, T.R. (Ted R.), Mini, G.K. (G. K.), Mirrakhimov, E.M. (Erkin M.), Moazen, B. (Babak), Darwesh, A.M. (Aso Mohammad), Mohammed, S. (Shafiu), Mohebi, F. (Farnam), Mokdad, A.H. (Ali H.), Moodley, Y. (Yoshan), Moradi, G. (Ghobad), Moradi-Lakeh, M. (Maziar), Moraga, P. (Paula), Morrison, S.D. (Shane Douglas), Mosser, J.F. (Jonathan F.), Mousavi, S.M. (Seyyed Meysam), Mueller, U.O. (Ulrich Otto), Murray, C.J.L. (Christopher J. L.), Mustafa, G. (Ghulam), Naderi, M. (Mehdi), Naghavi, M. (Morteza), Najafi, F. (Farid), Nangia, V. (Vinay), Ndwandwe, D.E. (Duduzile Edith), Negoi, I. (Ionut), Ngunjiri, J.W. (Josephine W.), Nguyen, H.L.T. (Huong Lan Thi), Nguyen, L.H. (Long Hoang), Nguyen, S.H. (Son Hoang), Nie, J. (Jing), Nnaji, C.A. (Chukwudi A.), Noubiap, J.J. (Jean Jacques), Shiadeh, M.N. (Malihe Nourollahpour), Nyasulu, P.S. (Peter S.), Ogbo, F.A. (Felix Akpojene), Olagunju, A.T. (Andrew T.), Olusanya, B.O. (Bolajoko O), Olusanya, J.O. (Jacob Olusegun), Ortiz-Panozo, E. (Eduardo), Otstavnov, S.S. (Stanislav S.), P. A, M. (Mahesh), Pana, A. (Adrian), Pandey, A. (Anamika), Pati, S. (Sanghamitra), Patil, S.T. (Snehal T.), Patton, G.C. (George C.), Perico, N. (Norberto), Pigott, D.M. (David M.), Pirsaheb, M. (Meghdad), Piwoz, E.G. (Ellen G.), Postma, M.J. (Maarten), Pourshams, A. (Akram), Prakash, S. (Swayam), Quintana, H. (Hedley), Radfar, A. (Amir), Rafiei, A. (Alireza), Rahimi-Movaghar, V. (Vafa), Rai, R.K. (Rajesh Kumar), Rajati, F. (Fatemeh), Rawaf, D.L. (David Laith), Rawaf, S. (Salman), Rawat, R. (Rahul), Remuzzi, G. (Giuseppe), Renzaho, A.M.N. (Andre M. N.), Rios-González, C. (Carlos), Roever, L. (Leonardo), Ross, J.M. (Jennifer M.), Rostami, A. (Ali), Sadat, N. (Nafis), Safari, Y. (Yahya), Safdarian, M. (Mahdi), Sahebkar, A. (Amirhossein), Salam, N. (Nasir), Salamati, P. (Payman), Salimi, Y. (Yahya), Salimzadeh, H. (Hamideh), Samy, A.M. (Abdallah M.), Sartorius, B. (Benn), Sathian, B. (Brijesh), Schipp, M.F. (Megan F.), Schwebel, D.C. (David C), Senbeta, A.M. (Anbissa Muleta), Sepanlou, S.G. (Sadaf G), Shaikh, M.A. (Masood Ali), Levy, T.S. (Teresa Shamah), Shamsi, M. (Mohammadbagher), Sharafi, K. (Kiomars), Sharma, R. (Rajesh), Sheikh, A. (Aziz), Shil, A. (Apurba), Silva, D.A.S. (Diego Augusto Santos), Singh, J.A. (Jasvinder A.), Sinha, D.N. (Dhirendra Narain), Soofi, M. (Moslem), Sudaryanto, A. (Agus), Sufiyan, M.B. (Muawiyyah Babale), Tabarés-Seisdedos, R. (Rafael), Tadesse, B.T. (Birkneh Tilahun), Temsah, M.-H. (Mohamad-Hani), Terkawi, A.S. (Abdullah Sulieman), Tessema, Z.T. (Zemenu Tadesse), Thorne-Lyman, A.L. (Andrew L.), Tovani-Palone, M.R. (Marcos Roberto), Tran, B.X. (Bach Xuan), Tran, K.B. (Khanh Bao), Ullah, I. (Irfan), Uthman, O.A. (Olalekan A.), Vaezghasemi, M. (Masoud), Vaezi, A. (Afsane), Valdez, P.R. (Pascual R.), Vanderheide, J. (John), Veisani, Y. (Yousef), Violante, F.S. (Francesco S), Vlassov, V. (Vasily), Vu, G.T. (Giang Thu), Vu, L.G. (Linh Gia), Waheed, Y. (Yasir), Walson, J.L. (Judd L.), Wang, Y. (Yafeng), Wang, Y.-P. (Yuan-Pang), Wangia, E.N. (Elizabeth N.), Werdecker, A. (Andrea), Xu, G. (Gelin), Yamada, T. (Tomohide), Yisma, E. (Engida), Yonemoto, N. (Naohiro), Younis, M.Z. (Mustafa Z.), Yousefifard, M. (Mahmoud), Yu, C. (Chuanhua), Zaman, S.B. (Sojib Bin), Zamani, M. (Mohammad), Zhang, Y. (Yunquan), Kassebaum, N.J. (Nicholas J.), and Hay, S.I. (Simon)
Abstract: Childhood malnutrition is associated with high morbidity and mortality globally1. Undernourished children are more likely to experience cognitive, physical, and metabolic developmental impairments that can lead to later cardiovascular disease, reduced intellectual ability and school attainment, and reduced economic productivity in adulthood2. Child growth failure (CGF), expressed as stunting, wasting, and underweight in children under five years of age (0–59 months), is a specific subset of undernutrition characterized by insufficient height or weight against age-specific growth reference standards3–5. The prevalence of stunting, wasting, or underweight in children under five is the proportion of children with a height-for-age, weight-for-height, or weight-for-age z-score, respectively, that is more than two standard deviations below the World Health Organization’s median growth reference standards for a healthy population6. Subnational estimates of CGF report substantial heterogeneity within countries, but are available primarily at the first administrative level (for example, states or provinces)7; the uneven geographical distribution of CGF has motivated further calls for assessments that can match the local scale of many public health programmes8. Building from our previous work mapping CGF in Africa9, here we provide the first, to our knowledge, mapped high-spatial-resolution estimates of CGF indicators from 2000 to 2017 across 105 low- and middle-income countries (LMICs), where 99% of affected children live1, aggregated to policy-relevant first and second (for example, districts or counties) administrative-level units and national levels. Despite remarkable declines over the study period, many LMICs remain far from the ambitious World Health Organization Global Nutrition Targets to reduce stunting by 40% and wasting to less than 5% by 2025. Large disparities in prevalence and progress exist across and within countries; our maps identify high-prevalence areas e
Published: 2020
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6. Erratum: Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 (The Lancet (2018) 392(10159) (1923–1994), (S0140673618322256), (10.1016/S0140-6736(18)32225-6))

Author: Stanaway, J.D. Afshin, A. Gakidou, E. Lim, S.S. Abate, D. Abate, K.H. Abbafati, C. Abbasi, N. Abbastabar, H. Abd-Allah, F. Abdela, J. Abdelalim, A. Abdollahpour, I. Abdulkader, R.S. Abebe, M. Abebe, Z. Abera, S.F. Abil, O.Z. Abraha, H.N. Abrham, A.R. Abu-Raddad, L.J. Abu-Rmeileh, N.M.E. Accrombessi, M.M.K. Acharya, D. Acharya, P. Adamu, A.A. Adane, A.A. Adebayo, O.M. Adedoyin, R.A. Adekanmbi, V. Ademi, Z. Adetokunboh, O.O. Adib, M.G. Admasie, A. Adsuar, J.C. Afanvi, K.A. Afarideh, M. Agarwal, G. Aggarwal, A. Aghayan, S.A. Agrawal, A. Agrawal, S. Ahmadi, A. Ahmadi, M. Ahmadieh, H. Ahmed, M.B. Aichour, A.N. Aichour, I. Aichour, M.T.E. Akbari, M.E. Akinyemiju, T. Akseer, N. Al-Aly, Z. Al-Eyadhy, A. Al-Mekhlafi, H.M. Alahdab, F. Alam, K. Alam, S. Alam, T. Alashi, A. Alavian, S.M. Alene, K.A. Ali, K. Ali, S.M. Alijanzadeh, M. Alizadeh-Navaei, R. Aljunid, S.M. Alkerwi, A. Alla, F. Alsharif, U. Altirkawi, K. Alvis-Guzman, N. Amare, A.T. Ammar, W. Anber, N.H. Anderson, J.A. Andrei, C.L. Androudi, S. Animut, M.D. Anjomshoa, M. Ansha, M.G. Antó, J.M. Antonio, C.A.T. Anwari, P. Appiah, L.T. Appiah, S.C.Y. Arabloo, J. Aremu, O. Ärnlöv, J. Artaman, A. Aryal, K.K. Asayesh, H. Ataro, Z. Ausloos, M. Avokpaho, E.F.G.A. Awasthi, A. Ayala Quintanilla, B.P. Ayer, R. Ayuk, T.B. Azzopardi, P.S. Babazadeh, A. Badali, H. Badawi, A. Balakrishnan, K. Bali, A.G. Ball, K. Ballew, S.H. Banach, M. Banoub, J.A.M. Barac, A. Barker-Collo, S.L. Bärnighausen, T.W. Barrero, L.H. Basu, S. Baune, B.T. Bazargan-Hejazi, S. Bedi, N. Beghi, E. Behzadifar, M. Behzadifar, M. Béjot, Y. Bekele, B.B. Bekru, E.T. Belay, E. Belay, Y.A. Bell, M.L. Bello, A.K. Bennett, D.A. Bensenor, I.M. Bergeron, G. Berhane, A. Bernabe, E. Bernstein, R.S. Beuran, M. Beyranvand, T. Bhala, N. Bhalla, A. Bhattarai, S. Bhutta, Z.A. Biadgo, B. Bijani, A. Bikbov, B. Bilano, V. Bililign, N. Bin Sayeed, M.S. Bisanzio, D. Biswas, T. Bjørge, T. Blacker, B.F. Bleyer, A. Borschmann, R. Bou-Orm, I.R. Boufous, S. Bourne, R. Brady, O.J. Brauer, M. Brazinova, A. Breitborde, N.J.K. Brenner, H. Briko, A.N. Britton, G. Brugha, T. Buchbinder, R. Burnett, R.T. Busse, R. Butt, Z.A. Cahill, L.E. Cahuana-Hurtado, L. Campos-Nonato, I.R. Cárdenas, R. Carreras, G. Carrero, J.J. Carvalho, F. Castañeda-Orjuela, C.A. Castillo Rivas, J. Castro, F. Catalá-López, F. Causey, K. Cercy, K.M. Cerin, E. Chaiah, Y. Chang, H.-Y. Chang, J.-C. Chang, K.-L. Charlson, F.J. Chattopadhyay, A. Chattu, V.K. Chee, M.L. Cheng, C.-Y. Chew, A. Chiang, P.P.-C. Chimed-Ochir, O. Chin, K.L. Chitheer, A. Choi, J.-Y.J. Chowdhury, R. Christensen, H. Christopher, D.J. Chung, S.-C. Cicuttini, F.M. Cirillo, M. Cohen, A.J. Collado-Mateo, D. Cooper, C. Cooper, O.R. Coresh, J. Cornaby, L. Cortesi, P.A. Cortinovis, M. Costa, M. Cousin, E. Criqui, M.H. Cromwell, E.A. Cundiff, D.K. Daba, A.K. Dachew, B.A. Dadi, A.F. Damasceno, A.A.M. Dandona, L. Dandona, R. Darby, S.C. Dargan, P.I. Daryani, A. Das Gupta, R. Das Neves, J. Dasa, T.T. Dash, A.P. Davitoiu, D.V. Davletov, K. De la Cruz-Góngora, V. De La Hoz, F.P. De Leo, D. De Neve, J.-W. Degenhardt, L. Deiparine, S. Dellavalle, R.P. Demoz, G.T. Denova-Gutiérrez, E. Deribe, K. Dervenis, N. Deshpande, A. Des Jarlais, D.C. Dessie, G.A. Deveber, G.A. Dey, S. Dharmaratne, S.D. Dhimal, M. Dinberu, M.T. Ding, E.L. Diro, H.D. Djalalinia, S. Do, H.P. Dokova, K. Doku, D.T. Doyle, K.E. Driscoll, T.R. Dubey, M. Dubljanin, E. Duken, E.E. Duncan, B.B. Duraes, A.R. Ebert, N. Ebrahimi, H. Ebrahimpour, S. Edvardsson, D. Effiong, A. Eggen, A.E. El Bcheraoui, C. El-Khatib, Z. Elyazar, I.R. Enayati, A. Endries, A.Y. Er, B. Erskine, H.E. Eskandarieh, S. Esteghamati, A. Estep, K. Fakhim, H. Faramarzi, M. Fareed, M. Farid, T.A. Sá Farinha, C.S.E. Farioli, A. Faro, A. Farvid, M.S. Farzaei, M.H. Fatima, B. Fay, K.A. Fazaeli, A.A. Feigin, V.L. Feigl, A.B. Fereshtehnejad, S.-M. Fernandes, E. Fernandes, J.C. Ferrara, G. Ferrari, A.J. Ferreira, M.L. Filip, I. Finger, J.D. Fischer, F. Foigt, N.A. Foreman, K.J. Fukumoto, T. Fullman, N. Fürst, T. Furtado, J.M. Futran, N.D. Gall, S. Gallus, S. Gamkrelidze, A. Ganji, M. Garcia-Basteiro, A.L. Gardner, W.M. Gebre, A.K. Gebremedhin, A.T. Gebremichael, T.G. Gelano, T.F. Geleijnse, J.M. Geramo, Y.C.D. Gething, P.W. Gezae, K.E. Ghadimi, R. Ghadiri, K. Ghasemi Falavarjani, K.G. Ghasemi-Kasman, M. Ghimire, M. Ghosh, R. Ghoshal, A.G. Giampaoli, S. Gill, P.S. Gill, T.K. Gillum, R.F. Ginawi, I.A. Giussani, G. Gnedovskaya, E.V. Godwin, W.W. Goli, S. Gómez-Dantés, H. Gona, P.N. Gopalani, S.V. Goulart, A.C. Grada, A. Grams, M.E. Grosso, G. Gugnani, H.C. Guo, Y. Gupta, R. Gupta, R. Gupta, T. Gutiérrez, R.A. Gutiérrez-Torres, D.S. Haagsma, J.A. Habtewold, T.D. Hachinski, V. Hafezi-Nejad, N. Hagos, T.B. Hailegiyorgis, T.T. Hailu, G.B. Haj-Mirzaian, A. Haj-Mirzaian, A. Hamadeh, R.R. Hamidi, S. Handal, A.J. Hankey, G.J. Hao, Y. Harb, H.L. Harikrishnan, S. Haro, J.M. Hassankhani, H. Hassen, H.Y. Havmoeller, R. Hawley, C.N. Hay, S.I. Hedayatizadeh-Omran, A. Heibati, B. Heidari, B. Heidari, M. Hendrie, D. Henok, A. Heredia-Pi, I. Herteliu, C. Heydarpour, F. Heydarpour, S. Hibstu, D.T. Higazi, T.B. Hilawe, E.H. Hoek, H.W. Hoffman, H.J. Hole, M.K. Homaie Rad, E. Hoogar, P. Hosgood, H.D. Hosseini, S.M. Hosseinzadeh, M. Hostiuc, M. Hostiuc, S. Hoy, D.G. Hsairi, M. Hsiao, T. Hu, G. Hu, H. Huang, J.J. Hussen, M.A. Huynh, C.K. Iburg, K.M. Ikeda, N. Ilesanmi, O.S. Iqbal, U. Irvani, S.S.N. Irvine, C.M.S. Islam, S.M.S. Islami, F. Jackson, M.D. Jacobsen, K.H. Jahangiry, L. Jahanmehr, N. Jain, S.K. Jakovljevic, M. James, S.L. Jassal, S.K. Jayatilleke, A.U. Jeemon, P. Jha, R.P. Jha, V. Ji, J.S. Jonas, J.B. Jonnagaddala, J. Jorjoran Shushtari, Z.J. Joshi, A. Jozwiak, J.J. Jürisson, M. Kabir, Z. Kahsay, A. Kalani, R. Kanchan, T. Kant, S. Kar, C. Karami, M. Karami Matin, B.K. Karch, A. Karema, C. Karimi, N. Karimi, S.M. Kasaeian, A. Kassa, D.H. Kassa, G.M. Kassa, T.D. Kassebaum, N.J. Katikireddi, S.V. Kaul, A. Kawakami, N. Kazemi, Z. Kazemi Karyani, A. Kefale, A.T. Keiyoro, P.N. Kemp, G.R. Kengne, A.P. Keren, A. Kesavachandran, C.N. Khader, Y.S. Khafaei, B. Khafaie, M.A. Khajavi, A. Khalid, N. Khalil, I.A. Khan, G. Khan, M.S. Khan, M.A. Khang, Y.-H. Khater, M.M. Khazaei, M. Khazaie, H. Khoja, A.T. Khosravi, A. Khosravi, M.H. Kiadaliri, A.A. Kiirithio, D.N. Kim, C.-I. Kim, D. Kim, Y.-E. Kim, Y.J. Kimokoti, R.W. Kinfu, Y. Kisa, A. Kissimova-Skarbek, K. Kivimäki, M. Knibbs, L.D. Knudsen, A.K.S. Kochhar, S. Kokubo, Y. Kolola, T. Kopec, J.A. Kosen, S. Koul, P.A. Koyanagi, A. Kravchenko, M.A. Krishan, K. Krohn, K.J. Kromhout, H. Kuate Defo, B. Kucuk Bicer, B. Kumar, G.A. Kumar, M. Kuzin, I. Kyu, H.H. Lachat, C. Lad, D.P. Lad, S.D. Lafranconi, A. Lalloo, R. Lallukka, T. Lami, F.H. Lang, J.J. Lansingh, V.C. Larson, S.L. Latifi, A. Lazarus, J.V. Lee, P.H. Leigh, J. Leili, M. Leshargie, C.T. Leung, J. Levi, M. Lewycka, S. Li, S. Li, Y. Liang, J. Liang, X. Liao, Y. Liben, M.L. Lim, L.-L. Linn, S. Liu, S. Lodha, R. Logroscino, G. Lopez, A.D. Lorkowski, S. Lotufo, P.A. Lozano, R. Lucas, T.C.D. Lunevicius, R. Ma, S. Macarayan, E.R.K. Machado, Í.E. Madotto, F. Mai, H.T. Majdan, M. Majdzadeh, R. Majeed, A. Malekzadeh, R. Malta, D.C. Mamun, A.A. Manda, A.-L. Manguerra, H. Mansournia, M.A. Mantovani, L.G. Maravilla, J.C. Marcenes, W. Marks, A. Martin, R.V. Martins, S.C.O. Martins-Melo, F.R. März, W. Marzan, M.B. Massenburg, B.B. Mathur, M.R. Mathur, P. Matsushita, K. Maulik, P.K. Mazidi, M. McAlinden, C. McGrath, J.J. McKee, M. Mehrotra, R. Mehta, K.M. Mehta, V. Meier, T. Mekonnen, F.A. Melaku, Y.A. Melese, A. Melku, M. Memiah, P.N. Memish, Z.A. Mendoza, W. Mengistu, D.T. Mensah, G.A. Mensink, G.B.M. Mereta, S.T. Meretoja, A. Meretoja, T.J. Mestrovic, T. Mezgebe, H.B. Miazgowski, B. Miazgowski, T. Millear, A.I. Miller, T.R. Miller-Petrie, M.K. Mini, G.K. Mirarefin, M. Mirica, A. Mirrakhimov, E.M. Misganaw, A.T. Mitiku, H. Moazen, B. Mohajer, B. Mohammad, K.A. Mohammadi, M. Mohammadifard, N. Mohammadnia-Afrouzi, M. Mohammed, S. Mohebi, F. Mokdad, A.H. Molokhia, M. Momeniha, F. Monasta, L. Moodley, Y. Moradi, G. Moradi-Lakeh, M. Moradinazar, M. Moraga, P. Morawska, L. Morgado-Da-Costa, J. Morrison, S.D. Moschos, M.M. Mouodi, S. Mousavi, S.M. Mozaffarian, D. Mruts, K.B. Muche, A.A. Muchie, K.F. Mueller, U.O. Muhammed, O.S. Mukhopadhyay, S. Muller, K. Musa, K.I. Mustafa, G. Nabhan, A.F. Naghavi, M. Naheed, A. Nahvijou, A. Naik, G. Naik, N. Najafi, F. Nangia, V. Nansseu, J.R. Nascimento, B.R. Neal, B. Neamati, N. Negoi, I. Negoi, R.I. Neupane, S. Newton, C.R.J. Ngunjiri, J.W. Nguyen, A.Q. Nguyen, G. Nguyen, H.T. Nguyen, H.L.T. Nguyen, H.T. Nguyen, M. Nguyen, N.B. Nichols, E. Nie, J. Ningrum, D.N.A. Nirayo, Y.L. Nishi, N. Nixon, M.R. Nojomi, M. Nomura, S. Norheim, O.F. Noroozi, M. Norrving, B. Noubiap, J.J. Nouri, H.R. Nourollahpour Shiadeh, M. Nowroozi, M.R. Nsoesie, E.O. Nyasulu, P.S. Obermeyer, C.M. Odell, C.M. Ofori-Asenso, R. Ogbo, F.A. Oh, I.-H. Oladimeji, O. Olagunju, A.T. Olagunju, T.O. Olivares, P.R. Olsen, H.E. Olusanya, B.O. Olusanya, J.O. Ong, K.L. Ong, S.K. Oren, E. Orpana, H.M. Ortiz, A. Ota, E. Otstavnov, S.S. Øverland, S. Owolabi, M.O. Mahesh, P.A. Pacella, R. Pakhare, A.P. Pakpour, A.H. Pana, A. Panda-Jonas, S. Park, E.-K. Parry, C.D.H. Parsian, H. Patel, S. Pati, S. Patil, S.T. Patle, A. Patton, G.C. Paudel, D. Paulson, K.R. Paz Ballesteros, W.C. Pearce, N. Pereira, A. Pereira, D.M. Perico, N. Pesudovs, K. Petzold, M. Pham, H.Q. Phillips, M.R. Pillay, J.D. Piradov, M.A. Pirsaheb, M. Pischon, T. Pishgar, F. Plana-Ripoll, O. Plass, D. Polinder, S. Polkinghorne, K.R. Postma, M.J. Poulton, R. Pourshams, A. Poustchi, H. Prabhakaran, D. Prakash, S. Prasad, N. Purcell, C.A. Purwar, M.B. Qorbani, M. Radfar, A. Rafay, A. Rafiei, A. Rahim, F. Rahimi, Z. Rahimi-Movaghar, A. Rahimi-Movaghar, V. Rahman, M. Rahman, M.H.U. Rahman, M.A. Rai, R.K. Rajati, F. Rajsic, S. Raju, S.B. Ram, U. Ranabhat, C.L. Ranjan, P. Rath, G.K. Rawaf, D.L. Rawaf, S. Reddy, K.S. Rehm, C.D. Rehm, J. Reiner, R.C. Reitsma, M.B. Remuzzi, G. Renzaho, A.M.N. Resnikoff, S. Reynales-Shigematsu, L.M. Rezaei, S. Ribeiro, A.L.P. Rivera, J.A. Roba, K.T. Rodríguez-Ramírez, S. Roever, L. Román, Y. Ronfani, L. Roshandel, G. Rostami, A. Roth, G.A. Rothenbacher, D. Roy, A. Rubagotti, E. Rushton, L. Sabanayagam, C. Sachdev, P.S. Saddik, B. Sadeghi, E. Saeedi Moghaddam, S. Safari, H. Safari, Y. Safari-Faramani, R. Safdarian, M. Safi, S. Safiri, S. Sagar, R. Sahebkar, A. Sahraian, M.A. Sajadi, H.S. Salam, N. Salamati, P. Saleem, Z. Salimi, Y. Salimzadeh, H. Salomon, J.A. Salvi, D.D. Salz, I. Samy, A.M. Sanabria, J. Sanchez-Niño, M.D. Sánchez-Pimienta, T.G. Sanders, T. Sang, Y. Santomauro, D.F. Santos, I.S. Santos, J.V. Santric Milicevic, M.M. Sao Jose, B.P. Sardana, M. Sarker, A.R. Sarmiento-Suárez, R. Sarrafzadegan, N. Sartorius, B. Sarvi, S. Sathian, B. Satpathy, M. Sawant, A.R. Sawhney, M. Saylan, M. Sayyah, M. Schaeffner, E. Schmidt, M.I. Schneider, I.J.C. Schöttker, B. Schutte, A.E. Schwebel, D.C. Schwendicke, F. Scott, J.G. Seedat, S. Sekerija, M. Sepanlou, S.G. Serre, M.L. Serván-Mori, E. Seyedmousavi, S. Shabaninejad, H. Shaddick, G. Shafieesabet, A. Shahbazi, M. Shaheen, A.A. Shaikh, M.A. Shamah Levy, T. Shams-Beyranvand, M. Shamsi, M. Sharafi, H. Sharafi, K. Sharif, M. Sharif-Alhoseini, M. Sharifi, H. Sharma, J. Sharma, M. Sharma, R. She, J. Sheikh, A. Shi, P. Shibuya, K. Shiferaw, M.S. Shigematsu, M. Shin, M.-J. Shiri, R. Shirkoohi, R. Shiue, I. Shokraneh, F. Shoman, H. Shrime, M.G. Shupler, M.S. Si, S. Siabani, S. Sibai, A.M. Siddiqi, T.J. Sigfusdottir, I.D. Sigurvinsdottir, R. Silva, D.A.S. Silva, J.P. Silveira, D.G.A. Singh, J.A. Singh, N.P. Singh, V. Sinha, D.N. Skiadaresi, E. Skirbekk, V. Smith, D.L. Smith, M. Sobaih, B.H. Sobhani, S. Somayaji, R. Soofi, M. Sorensen, R.J.D. Soriano, J.B. Soyiri, I.N. Spinelli, A. Sposato, L.A. Sreeramareddy, C.T. Srinivasan, V. Starodubov, V.I. Steckling, N. Stein, D.J. Stein, M.B. Stevanovic, G. Stockfelt, L. Stokes, M.A. Sturua, L. Subart, M.L. Sudaryanto, A. Sufiyan, M.B. Sulo, G. Sunguya, B.F. Sur, P.J. Sykes, B.L. Szoeke, C.E.I. Tabarés-Seisdedos, R. Tabuchi, T. Tadakamadla, S.K. Takahashi, K. Tandon, N. Tassew, S.G. Tavakkoli, M. Taveira, N. Tehrani-Banihashemi, A. Tekalign, T.G. Tekelemedhin, S.W. Tekle, M.G. Temesgen, H. Temsah, M.-H. Temsah, O. Terkawi, A.S. Tessema, B. Teweldemedhin, M. Thankappan, K.R. Theis, A. Thirunavukkarasu, S. Thomas, H.J. Thomas, M.L. Thomas, N. Thurston, G.D. Tilahun, B. Tillmann, T. To, Q.G. Tobollik, M. Tonelli, M. Topor-Madry, R. Torre, A.E. Tortajada-Girbés, M. Touvier, M. Tovani-Palone, M.R. Towbin, J.A. Tran, B.X. Tran, K.B. Truelsen, T.C. Truong, N.T. Tsadik, A.G. Tudor Car, L. Tuzcu, E.M. Tymeson, H.D. Tyrovolas, S. Ukwaja, K.N. Ullah, I. Updike, R.L. Usman, M.S. Uthman, O.A. Vaduganathan, M. Vaezi, A. Valdez, P.R. Van Donkelaar, A. Varavikova, E. Varughese, S. Vasankari, T.J. Venkateswaran, V. Venketasubramanian, N. Villafaina, S. Violante, F.S. Vladimirov, S.K. Vlassov, V. Vollset, S.E. Vos, T. Vosoughi, K. Vu, G.T. Vujcic, I.S. Wagnew, F.S. Waheed, Y. Waller, S.G. Walson, J.L. Wang, Y. Wang, Y. Wang, Y.-P. Weiderpass, E. Weintraub, R.H. Weldegebreal, F. Werdecker, A. Werkneh, A.A. West, J.J. Westerman, R. Whiteford, H.A. Widecka, J. Wijeratne, T. Winkler, A.S. Wiyeh, A.B. Wiysonge, C.S. Wolfe, C.D.A. Wong, T.Y. Wu, S. Xavier, D. Xu, G. Yadgir, S. Yadollahpour, A. Yahyazadeh Jabbari, S.H. Yamada, T. Yan, L.L. Yano, Y. Yaseri, M. Yasin, Y.J. Yeshaneh, A. Yimer, E.M. Yip, P. Yisma, E. Yonemoto, N. Yoon, S.-J. Yotebieng, M. Younis, M.Z. Yousefifard, M. Yu, C. Zaidi, Z. Zaman, S.B. Zamani, M. Zavala-Arciniega, L. Zhang, A.L. Zhang, H. Zhang, K. Zhou, M. Zimsen, S.R.M. Zodpey, S. Murray, C.J.L. GBD 2017 Risk Factor Collaborators
Abstract: Background The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 comparative risk assessment (CRA) is a comprehensive approach to risk factor quantification that offers a useful tool for synthesising evidence on risks and risk–outcome associations. With each annual GBD study, we update the GBD CRA to incorporate improved methods, new risks and risk–outcome pairs, and new data on risk exposure levels and risk–outcome associations. Methods We used the CRA framework developed for previous iterations of GBD to estimate levels and trends in exposure, attributable deaths, and attributable disability-adjusted life-years (DALYs), by age group, sex, year, and location for 84 behavioural, environmental and occupational, and metabolic risks or groups of risks from 1990 to 2017. This study included 476 risk–outcome pairs that met the GBD study criteria for convincing or probable evidence of causation. We extracted relative risk and exposure estimates from 46 749 randomised controlled trials, cohort studies, household surveys, census data, satellite data, and other sources. We used statistical models to pool data, adjust for bias, and incorporate covariates. Using the counterfactual scenario of theoretical minimum risk exposure level (TMREL), we estimated the portion of deaths and DALYs that could be attributed to a given risk. We explored the relationship between development and risk exposure by modelling the relationship between the Socio-demographic Index (SDI) and risk-weighted exposure prevalence and estimated expected levels of exposure and risk-attributable burden by SDI. Finally, we explored temporal changes in risk-attributable DALYs by decomposing those changes into six main component drivers of change as follows: (1) population growth; (2) changes in population age structures; (3) changes in exposure to environmental and occupational risks; (4) changes in exposure to behavioural risks; (5) changes in exposure to metabolic risks; and (6) changes due to all other factors, approximated as the risk-deleted death and DALY rates, where the risk-deleted rate is the rate that would be observed had we reduced the exposure levels to the TMREL for all risk factors included in GBD 2017. Findings In 2017, 34·1 million (95% uncertainty interval [UI] 33·3–35·0) deaths and 1·21 billion (1·14–1·28) DALYs were attributable to GBD risk factors. Globally, 61·0% (59·6–62·4) of deaths and 48·3% (46·3–50·2) of DALYs were attributed to the GBD 2017 risk factors. When ranked by risk-attributable DALYs, high systolic blood pressure (SBP) was the leading risk factor, accounting for 10·4 million (9·39–11·5) deaths and 218 million (198–237) DALYs, followed by smoking (7·10 million [6·83–7·37] deaths and 182 million [173–193] DALYs), high fasting plasma glucose (6·53 million [5·23–8·23] deaths and 171 million [144–201] DALYs), high body-mass index (BMI; 4·72 million [2·99–6·70] deaths and 148 million [98·6–202] DALYs), and short gestation for birthweight (1·43 million [1·36–1·51] deaths and 139 million [131–147] DALYs). In total, risk-attributable DALYs declined by 4·9% (3·3–6·5) between 2007 and 2017. In the absence of demographic changes (ie, population growth and ageing), changes in risk exposure and risk-deleted DALYs would have led to a 23·5% decline in DALYs during that period. Conversely, in the absence of changes in risk exposure and risk-deleted DALYs, demographic changes would have led to an 18·6% increase in DALYs during that period. The ratios of observed risk exposure levels to exposure levels expected based on SDI (O/E ratios) increased globally for unsafe drinking water and household air pollution between 1990 and 2017. This result suggests that development is occurring more rapidly than are changes in the underlying risk structure in a population. Conversely, nearly universal declines in O/E ratios for smoking and alcohol use indicate that, for a given SDI, exposure to these risks is declining. In 2017, the leading Level 4 risk factor for age-standardised DALY rates was high SBP in four super-regions: central Europe, eastern Europe, and central Asia; north Africa and Middle East; south Asia; and southeast Asia, east Asia, and Oceania. The leading risk factor in the high-income super-region was smoking, in Latin America and Caribbean was high BMI, and in sub-Saharan Africa was unsafe sex. O/E ratios for unsafe sex in sub-Saharan Africa were notably high, and those for alcohol use in north Africa and the Middle East were notably low. Interpretation By quantifying levels and trends in exposures to risk factors and the resulting disease burden, this assessment offers insight into where past policy and programme efforts might have been successful and highlights current priorities for public health action. Decreases in behavioural, environmental, and occupational risks have largely offset the effects of population growth and ageing, in relation to trends in absolute burden. Conversely, the combination of increasing metabolic risks and population ageing will probably continue to drive the increasing trends in non-communicable diseases at the global level, which presents both a public health challenge and opportunity. We see considerable spatiotemporal heterogeneity in levels of risk exposure and risk-attributable burden. Although levels of development underlie some of this heterogeneity, O/E ratios show risks for which countries are overperforming or underperforming relative to their level of development. As such, these ratios provide a benchmarking tool to help to focus local decision making. Our findings reinforce the importance of both risk exposure monitoring and epidemiological research to assess causal connections between risks and health outcomes, and they highlight the usefulness of the GBD study in synthesising data to draw comprehensive and robust conclusions that help to inform good policy and strategic health planning. Copyright © 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.
Published: 2019

7. Global, regional, and national burden of traumatic brain injury and spinal cord injury, 1990-2016: A systematic analysis for the Global Burden of Disease Study 2016

Author: James, S.L. Bannick, M.S. Montjoy-Venning, W.C. Lucchesi, L.R. Dandona, L. Dandona, R. Hawley, C. Hay, S.I. Jakovljevic, M. Khalil, I. Krohn, K.J. Mokdad, A.H. Naghavi, M. Nichols, E. Reiner, R.C. Smith, M. Feigin, V.L. Vos, T. Murray, C.J.L. Sunshine, J.E. Yost, M.G. Ellenbogen, R.G. Kalani, R. Morrison, S.D. Crowe, C.S. Massenburg, B.B. Theadom, A. Te Ao, B.J. Balalla, S. Jones, K.M. Ofori-Asenso, R. Li, S. Sobhani, S. Hosseini, S.M. Mansournia, M.A. Yaseri, M. Anjomshoa, M. Mousavi, S.M. Haj-Mirzaian, A. Haj-Mirzaian, A. Malekzadeh, R. Poustchi, H. Roshandel, G. Sepanlou, S.G. Afarideh, M. Esteghamati, A. Esteghamati, S. Ganji, M. Kasaeian, A. Rahimi-Movaghar, A. Eskandarieh, S. Sahraian, M.A. Shams-Beyranvand, M. Abbasi, N. Farzadfar, F. Irvani, S.N. Rahimi-Movaghar, V. Salamati, P. Sharif-Alhoseini, M. Fereshtehnejad, S.-M. Mate, K.K.V. Abdulkader, R. Abraha, H.N. Kassa, T.D. Nirayo, Y.L. Weldegwergs, K.G. Gezae, K.E. Zenebe, Z.M. Degefa, M.G. Kahsay, A. Asgedom, S.W. Gebre, A.K. Yimer, E.M. Belachew, A.B. Meles, H. Adsuar, J.C. Zodpey, S. Agrawal, S. Awasthi, A. Kumar, G.A. Ahmadi, A. Najafi, F. Rajati, F. Khazaie, H. Farzaei, M.H. Moradi, M. Rezaei, S. Soofi, M. Siabani, S. Rezaeian, S. Ahmed, M.B. Gebrehiwot, T.T. Feyissa, G.T. Hussen, M.A. Aichour, A. Aichour, I. Aichour, M.T.E. Akinyemi, R.O. Owolabi, M.O. Akseer, N. Bhutta, Z.A. Badawi, A. Alahdab, F. Kassa, G.M. Alebel, A. Wagnew, F.W.S. Belay, Y.A. Leshargie, C.T. Alghnam, S.A. Ali, B.A. Alsharif, U. Temsah, M.-H. Altirkawi, K. Davitoiu, D.V. Hostiuc, S. Beuran, M. Negoi, I. Andrei, C.L. Ansari, H. Ansha, M.G. Antonio, C.A.T. Appiah, S.C.Y. Levi, M. Ariani, F. Biffino, M. Asefa, N.G. Atique, S. Rahman, M.A. Wijeratne, T. Ayala Quintanilla, B.P. Ayuk, T.B. Azzopardi, P.S. Rafiei, A. Badali, H. Mohammadi, M. Moosazadeh, M. Daryani, A. Banstola, A. Tran, K.B. Barker-Collo, S.L. Bärnighausen, T.W. Bedi, N. Tehrani-Banihashemi, A. Shabaninejad, H. Behzadifar, Ma. Kabir, A. Yousefifard, M. Moradi-Lakeh, M. Behzadifar, Me. Bekele, B. Hassen, H.Y. Henok, A. Biadgo, B. Bennett, D.A. Goulart, A.C. Bensenor, I.M. Lotufo, P.A. Wang, Y.P. Yisma, E. Berhane, A. Deribe, K. Yasin, Y.J. Demoz, G.T. Bhalla, A. Bhaumik, S. Bijani, A. Zamani, M. Bililign, N. Kumar, M. Birungi, C. Boufous, S. Brazinova, A. Brown, A.W. Car, M. Majeed, A. Rawaf, S. Rawaf, D.L. Shoman, H. Cárdenas, R. Carrero, J.J. El-Khatib, Z. Roy, N. Carvalho, F. Santos, J.V. Fernandes, E. Silva, J.P. Castañeda-Orjuela, C.A. Hoffman, H.J. Catalá-López, F. Chaiah, Y. Temsah, O. Champs, A.P. Chang, J.-C. Choi, J.-Y.J. Christopher, D.J. Cooper, C. Djalalinia, S. Do, H.P. Nguyen, T.H. Doku, D.T. Drake, T.M. Sheikh, A. Soyiri, I.N. Dubey, M. Santric Milicevic, M.M.M. Dubljanin, E. Faro, A. Filip, I. Radfar, A. Fischer, F. Fukumoto, T. Gankpe, F.G. Gopalkrishna, G. Haagsma, J.A. Polinder, S. Khoja, A.T. Pinilla-Monsalve, G.D. Hamadeh, R.R. Hamidi, S. Haro, J.M. Hassankhani, H. Havmoeller, R. Hegazy, M.I. Hendrie, D. Miller, T.R. Hibstu, D.T. Kassa, Z.Y. Hole, M.K. Homaie Rad, E. Hu, G. Ilesanmi, O.S. Jayaraman, S. Jha, R.P. Jonas, J.B. Moazen, B. Jorjoran Shushtari, Z. Jozwiak, J.J. Jürisson, M. Kahssay, M. Liben, M.L. Karch, A. Kengne, A.P. Khader, Y.S. Safari, H. Khafaie, M.A. Khalid, N. Khan, E.A. Khan, M.S. Usman, M.S. Siddiqi, T.J. Khang, Y.-H. Khubchandani, J. Kiadaliri, A.A. Kim, D. Kim, Y.-E. Yoon, S.-J. Kisa, A. Winkler, A.S. Koyanagi, A. Kuate Defo, B. Kucuk Bicer, B. Lalloo, R. Moradinazar, M. Lami, F.H. Lansingh, V.C. Laryea, D.O. Latifi, A. Safiri, S. Lunevicius, R. Mahotra, N.B. Majdan, M. Manda, A.-L. Mehndiratta, M.M. Mehta, V. Melese, A. Memiah, P.T.N. Mendoza, W. Mengistu, G. Shiferaw, M.S. Tekle, M.G. Meretoja, T.J. Meretoja, A. Szoeke, C.E.I. Mestrovich, T. Miazgowski, T. Mini, G.K. Mirica, A. Mirrakhimov, E.M. Molokhia, M. Monast, L. Ronfani, L. Mondello, S. Moradi, G. Moschos, M.M. Murthy, S. Musa, K.I. Mustafa, G. Naik, G. Schwebel, D.C. Nangia, V. Nascimento, B.R. Ningrum, D.N.A. Nyasulu, P.S. Renzaho, A.M.N. Ogbo, F.A. Oh, I.-H. Okoro, A. Olagunju, A.T. Olagunju, T.O. Olivares, P.R. Otstavnov, S.S. Dnb, M.P.A. Pakhale, S. Pandey, A.R. Pesudovs, K. Prakash, S. Qorbani, M. Rafay, A. Rahman, M. Stokes, M.A. Shariful Islam, S.M. Rai, R.K. Ram, U. Reis, C. Resnikoff, S. Roever, L. Sunguy, B.F. Ruhago, G.M. Saddik, B. Saldanha, R.D.F. Samy, A.M. Sanabria, J. Sartorius, B. Satpathy, M. Schneider, I.J.C. Shaikh, M.A.A. Sharif, M. She, J. Shen, J. Sheth, K.N. Shibuya, K. Shigematsu, M. Shiri, R. Shiue, I. Silveira, D.A. Soares Filho, A.M. Sinha, D.N. Soriano, J.B. Stein, D.J. Sufiyan, M.B. Sykes, B.L. Tabarés-Seisdedos, R. Tortajada-Girbés, M. Topor-Madry, R. Tran, B.X. Tudor Car, L. Ukwaja, K.N. Ullah, I. Uthman, O.A. Valdez, P.R. Vasankari, T.J. Venketasubramanian, N. Violante, F.S. Waheed, Y. Werdecker, A. Wyper, G.M.A. Yano, Y. Ye, P. Yip, P. Yonemoto, N. Younis, M.Z. Yu, C. Zaidi, Z. Zaman, S.B. GBD 2016 Traumatic Brain Injury Spinal Cord Injury Collaborators
Abstract: Background Traumatic brain injury (TBI) and spinal cord injury (SCI) are increasingly recognised as global health priorities in view of the preventability of most injuries and the complex and expensive medical care they necessitate. We aimed to measure the incidence, prevalence, and years of life lived with disability (YLDs) for TBI and SCI from all causes of injury in every country, to describe how these measures have changed between 1990 and 2016, and to estimate the proportion of TBI and SCI cases caused by different types of injury. Methods We used results from the Global Burden of Diseases, Injuries, and Risk Factors (GBD) Study 2016 to measure the global, regional, and national burden of TBI and SCI by age and sex. We measured the incidence and prevalence of all causes of injury requiring medical care in inpatient and outpatient records, literature studies, and survey data. By use of clinical record data, we estimated the proportion of each cause of injury that required medical care that would result in TBI or SCI being considered as the nature of injury. We used literature studies to establish standardised mortality ratios and applied differential equations to convert incidence to prevalence of long-term disability. Finally, we applied GBD disability weights to calculate YLDs. We used a Bayesian meta-regression tool for epidemiological modelling, used causespecific mortality rates for non-fatal estimation, and adjusted our results for disability experienced with comorbid conditions. We also analysed results on the basis of the Socio-demographic Index, a compound measure of income per capita, education, and fertility. Findings In 2016, there were 27.08 million (95% uncertainty interval [UI] 24.30-30.30 million) new cases of TBI and 0.93 million (0.78-1.16 million) new cases of SCI, with age-standardised incidence rates of 369 (331-412) per 100 000 population for TBI and 13 (11-16) per 100 000 for SCI. In 2016, the number of prevalent cases of TBI was 55.50 million (53.40-57.62 million) and of SCI was 27.04 million (24.98-30.15 million). From 1990 to 2016, the agestandardised prevalence of TBI increased by 8.4% (95% UI 7.7 to 9.2), whereas that of SCI did not change significantly (-0.2% [-2.1 to 2.7]). Age-standardised incidence rates increased by 3.6% (1.8 to 5.5) for TBI, but did not change significantly for SCI (-3.6% [-7.4 to 4.0]). TBI caused 8.1 million (95% UI 6.0-10.4 million) YLDs and SCI caused 9.5 million (6.7-12.4 million) YLDs in 2016, corresponding to age-standardised rates of 111 (82-141) per 100 000 for TBI and 130 (90-170) per 100 000 for SCI. Falls and road injuries were the leading causes of new cases of TBI and SCI in most regions. Interpretation TBI and SCI constitute a considerable portion of the global injury burden and are caused primarily by falls and road injuries. The increase in incidence of TBI over time might continue in view of increases in population density, population ageing, and increasing use of motor vehicles, motorcycles, and bicycles. The number of individuals living with SCI is expected to increase in view of population growth, which is concerning because of the specialised care that people with SCI can require. Our study was limited by data sparsity in some regions, and it will be important to invest greater resources in collection of data for TBI and SCI to improve the accuracy of future assessments. © 2018 The Author(s).
Published: 2019

8. Global, regional, and national burden of neurological disorders, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

Author: Feigin, V.L. Nichols, E. Alam, T. Bannick, M.S. Beghi, E. Blake, N. Culpepper, W.J. Dorsey, E.R. Elbaz, A. Ellenbogen, R.G. Fisher, J.L. Fitzmaurice, C. Giussani, G. Glennie, L. James, S.L. Johnson, C.O. Kassebaum, N.J. Logroscino, G. Marin, B. Mountjoy-Venning, W.C. Nguyen, M. Ofori-Asenso, R. Patel, A.P. Piccininni, M. Roth, G.A. Steiner, T.J. Stovner, L.J. Szoeke, C.E.I. Theadom, A. Vollset, S.E. Wallin, M.T. Wright, C. Zunt, J.R. Abbasi, N. Abd-Allah, F. Abdelalim, A. Abdollahpour, I. Aboyans, V. Abraha, H.N. Acharya, D. Adamu, A.A. Adebayo, O.M. Adeoye, A.M. Adsuar, J.C. Afarideh, M. Agrawal, S. Ahmadi, A. Ahmed, M.B. Aichour, A.N. Aichour, I. Aichour, M.T.E. Akinyemi, R.O. Akseer, N. Al-Eyadhy, A. Al-Shahi Salman, R. Alahdab, F. Alene, K.A. Aljunid, S.M. Altirkawi, K. Alvis-Guzman, N. Anber, N.H. Antonio, C.A.T. Arabloo, J. Aremu, O. Ärnlöv, J. Asayesh, H. Asghar, R.J. Atalay, H.T. Awasthi, A. Ayala Quintanilla, B.P. Ayuk, T.B. Badawi, A. Banach, M. Banoub, J.A.M. Barboza, M.A. Barker-Collo, S.L. Bärnighausen, T.W. Baune, B.T. Bedi, N. Behzadifar, M. Behzadifar, M. Béjot, Y. Bekele, B.B. Belachew, A.B. Bennett, D.A. Bensenor, I.M. Berhane, A. Beuran, M. Bhattacharyya, K. Bhutta, Z.A. Biadgo, B. Bijani, A. Bililign, N. Bin Sayeed, M.S. Blazes, C.K. Brayne, C. Butt, Z.A. Campos-Nonato, I.R. Cantu-Brito, C. Car, M. Cárdenas, R. Carrero, J.J. Carvalho, F. Castañeda-Orjuela, C.A. Castro, F. Catalá-López, F. Cerin, E. Chaiah, Y. Chang, J.-C. Chatziralli, I. Chiang, P.P.-C. Christensen, H. Christopher, D.J. Cooper, C. Cortesi, P.A. Costa, V.M. Criqui, M.H. Crowe, C.S. Damasceno, A.A.M. Daryani, A. De la Cruz-Góngora, V. De La Hoz, F.P. De Leo, D. Degefa, M.G. Demoz, G.T. Deribe, K. Dharmaratne, S.D. Diaz, D. Dinberu, M.T. Djalalinia, S. Doku, D.T. Dubey, M. Dubljanin, E. Duken, E.E. Edvardsson, D. El-Khatib, Z. Endres, M. Endries, A.Y. Eskandarieh, S. Esteghamati, A. Esteghamati, S. Farhadi, F. Faro, A. Farzadfar, F. Farzaei, M.H. Fatima, B. Fereshtehnejad, S.-M. Fernandes, E. Feyissa, G.T. Filip, I. Fischer, F. Fukumoto, T. Ganji, M. Gankpe, F.G. Garcia-Gordillo, M.A. Gebre, A.K. Gebremichael, T.G. Gelaw, B.K. Geleijnse, J.M. Geremew, D. Gezae, K.E. Ghasemi-Kasman, M. Gidey, M.Y. Gill, P.S. Gill, T.K. Gnedovskaya, E.V. Goulart, A.C. Grada, A. Grosso, G. Guo, Y. Gupta, R. Gupta, R. Haagsma, J.A. Hagos, T.B. Haj-Mirzaian, A. Haj-Mirzaian, A. Hamadeh, R.R. Hamidi, S. Hankey, G.J. Hao, Y. Haro, J.M. Hassankhani, H. Hassen, H.Y. Havmoeller, R. Hay, S.I. Hegazy, M.I. Heidari, B. Henok, A. Heydarpour, F. Hoang, C.L. Hole, M.K. Homaie Rad, E. Hosseini, S.M. Hu, G. Igumbor, E.U. Ilesanmi, O.S. Irvani, S.S.N. Islam, S.M.S. Jakovljevic, M. Javanbakht, M. Jha, R.P. Jobanputra, Y.B. Jonas, J.B. Józwiak, J.J. Jürisson, M. Kahsay, A. Kalani, R. Kalkonde, Y. Kamil, T.A. Kanchan, T. Karami, M. Karch, A. Karimi, N. Kasaeian, A. Kassa, T.D. Kassa, Z.Y. Kaul, A. Kefale, A.T. Keiyoro, P.N. Khader, Y.S. Khafaie, M.A. Khalil, I.A. Khan, E.A. Khang, Y.-H. Khazaie, H. Kiadaliri, A.A. Kiirithio, D.N. Kim, A.S. Kim, D. Kim, Y.-E. Kim, Y.J. Kisa, A. Kokubo, Y. Koyanagi, A. Krishnamurthi, R.V. Kuate Defo, B. Kucuk Bicer, B. Kumar, M. Lacey, B. Lafranconi, A. Lansingh, V.C. Latifi, A. Leshargie, C.T. Li, S. Liao, Y. Linn, S. Lo, W.D. Lopez, J.C.F. Lorkowski, S. Lotufo, P.A. Lucas, R.M. Lunevicius, R. Mackay, M.T. Mahotra, N.B. Majdan, M. Majdzadeh, R. Majeed, A. Malekzadeh, R. Malta, D.C. Manafi, N. Mansournia, M.A. Mantovani, L.G. März, W. Mashamba-Thompson, T.P. Massenburg, B.B. Mate, K.K.V. McAlinden, C. McGrath, J.J. Mehta, V. Meier, T. Meles, H.G. Melese, A. Memiah, P.T.N. Memish, Z.A. Mendoza, W. Mengistu, D.T. Mengistu, G. Meretoja, A. Meretoja, T.J. Mestrovic, T. Miazgowski, B. Miazgowski, T. Miller, T.R. Mini, G.K. Mirrakhimov, E.M. Moazen, B. Mohajer, B. Mohammad Gholi Mezerji, N. Mohammadi, M. Mohammadi-Khanaposhtani, M. Mohammadibakhsh, R. Mohammadnia-Afrouzi, M. Mohammed, S. Mohebi, F. Mokdad, A.H. Monasta, L. Mondello, S. Moodley, Y. Moosazadeh, M. Moradi, G. Moradi-Lakeh, M. Moradinazar, M. Moraga, P. Moreno Velásquez, I. Morrison, S.D. Mousavi, S.M. Muhammed, O.S. Muruet, W. Musa, K.I. Mustafa, G. Naderi, M. Nagel, G. Naheed, A. Naik, G. Najafi, F. Nangia, V. Negoi, I. Negoi, R.I. Newton, C.R.J. Ngunjiri, J.W. Nguyen, C.T. Nguyen, L.H. Ningrum, D.N.A. Nirayo, Y.L. Nixon, M.R. Norrving, B. Noubiap, J.J. Nourollahpour Shiadeh, M. Nyasulu, P.S. Ogbo, F.A. Oh, I.-H. Olagunju, A.T. Olagunju, T.O. Olivares, P.R. Onwujekwe, O.E. Oren, E. Owolabi, M.O. A, M.P. Pakpour, A.H. Pan, W.-H. Panda-Jonas, S. Pandian, J.D. Patel, S.K. Pereira, D.M. Petzold, M. Pillay, J.D. Piradov, M.A. Polanczyk, G.V. Polinder, S. Postma, M.J. Poulton, R. Poustchi, H. Prakash, S. Prakash, V. Qorbani, M. Radfar, A. Rafay, A. Rafiei, A. Rahim, F. Rahimi-Movaghar, V. Rahman, M. Rahman, M.H.U. Rahman, M.A. Rajati, F. Ram, U. Ranta, A. Rawaf, D.L. Rawaf, S. Reinig, N. Reis, C. Renzaho, A.M.N. Resnikoff, S. Rezaeian, S. Rezai, M.S. Rios González, C.M. Roberts, N.L.S. Roever, L. Ronfani, L. Roro, E.M. Roshandel, G. Rostami, A. Sabbagh, P. Sacco, R.L. Sachdev, P.S. Saddik, B. Safari, H. Safari-Faramani, R. Safi, S. Safiri, S. Sagar, R. Sahathevan, R. Sahebkar, A. Sahraian, M.A. Salamati, P. Salehi Zahabi, S. Salimi, Y. Samy, A.M. Sanabria, J. Santos, I.S. Santric Milicevic, M.M. Sarrafzadegan, N. Sartorius, B. Sarvi, S. Sathian, B. Satpathy, M. Sawant, A.R. Sawhney, M. Schneider, I.J.C. Schöttker, B. Schwebel, D.C. Seedat, S. Sepanlou, S.G. Shabaninejad, H. Shafieesabet, A. Shaikh, M.A. Shakir, R.A. Shams-Beyranvand, M. Shamsizadeh, M. Sharif, M. Sharif-Alhoseini, M. She, J. Sheikh, A. Sheth, K.N. Shigematsu, M. Shiri, R. Shirkoohi, R. Shiue, I. Siabani, S. Siddiqi, T.J. Sigfusdottir, I.D. Sigurvinsdottir, R. Silberberg, D.H. Silva, J.P. Silveira, D.G.A. Singh, J.A. Sinha, D.N. Skiadaresi, E. Smith, M. Sobaih, B.H. Sobhani, S. Soofi, M. Soyiri, I.N. Sposato, L.A. Stein, D.J. Stein, M.B. Stokes, M.A. Sufiyan, M.B. Sykes, B.L. Sylaja, P. Tabarés-Seisdedos, R. Te Ao, B.J. Tehrani-Banihashemi, A. Temsah, M.-H. Temsah, O. Thakur, J.S. Thrift, A.G. Topor-Madry, R. Tortajada-Girbés, M. Tovani-Palone, M.R. Tran, B.X. Tran, K.B. Truelsen, T.C. Tsadik, A.G. Tudor Car, L. Ukwaja, K.N. Ullah, I. Usman, M.S. Uthman, O.A. Valdez, P.R. Vasankari, T.J. Vasanthan, R. Veisani, Y. Venketasubramanian, N. Violante, F.S. Vlassov, V. Vosoughi, K. Vu, G.T. Vujcic, I.S. Wagnew, F.S. Waheed, Y. Wang, Y.-P. Weiderpass, E. Weiss, J. Whiteford, H.A. Wijeratne, T. Winkler, A.S. Wiysonge, C.S. Wolfe, C.D.A. Xu, G. Yadollahpour, A. Yamada, T. Yano, Y. Yaseri, M. Yatsuya, H. Yimer, E.M. Yip, P. Yisma, E. Yonemoto, N. Yousefifard, M. Yu, C. Zaidi, Z. Zaman, S.B. Zamani, M. Zandian, H. Zare, Z. Zhang, Y. Zodpey, S. Naghavi, M. Murray, C.J.L. Vos, T. GBD 2016 Neurology Collaborators
Abstract: Background: Neurological disorders are increasingly recognised as major causes of death and disability worldwide. The aim of this analysis from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 is to provide the most comprehensive and up-to-date estimates of the global, regional, and national burden from neurological disorders. Methods: We estimated prevalence, incidence, deaths, and disability-adjusted life-years (DALYs; the sum of years of life lost [YLLs] and years lived with disability [YLDs]) by age and sex for 15 neurological disorder categories (tetanus, meningitis, encephalitis, stroke, brain and other CNS cancers, traumatic brain injury, spinal cord injury, Alzheimer's disease and other dementias, Parkinson's disease, multiple sclerosis, motor neuron diseases, idiopathic epilepsy, migraine, tension-type headache, and a residual category for other less common neurological disorders) in 195 countries from 1990 to 2016. DisMod-MR 2.1, a Bayesian meta-regression tool, was the main method of estimation of prevalence and incidence, and the Cause of Death Ensemble model (CODEm) was used for mortality estimation. We quantified the contribution of 84 risks and combinations of risk to the disease estimates for the 15 neurological disorder categories using the GBD comparative risk assessment approach. Findings: Globally, in 2016, neurological disorders were the leading cause of DALYs (276 million [95% UI 247–308]) and second leading cause of deaths (9·0 million [8·8–9·4]). The absolute number of deaths and DALYs from all neurological disorders combined increased (deaths by 39% [34–44] and DALYs by 15% [9–21]) whereas their age-standardised rates decreased (deaths by 28% [26–30] and DALYs by 27% [24–31]) between 1990 and 2016. The only neurological disorders that had a decrease in rates and absolute numbers of deaths and DALYs were tetanus, meningitis, and encephalitis. The four largest contributors of neurological DALYs were stroke (42·2% [38·6–46·1]), migraine (16·3% [11·7–20·8]), Alzheimer's and other dementias (10·4% [9·0–12·1]), and meningitis (7·9% [6·6–10·4]). For the combined neurological disorders, age-standardised DALY rates were significantly higher in males than in females (male-to-female ratio 1·12 [1·05–1·20]), but migraine, multiple sclerosis, and tension-type headache were more common and caused more burden in females, with male-to-female ratios of less than 0·7. The 84 risks quantified in GBD explain less than 10% of neurological disorder DALY burdens, except stroke, for which 88·8% (86·5–90·9) of DALYs are attributable to risk factors, and to a lesser extent Alzheimer's disease and other dementias (22·3% [11·8–35·1] of DALYs are risk attributable) and idiopathic epilepsy (14·1% [10·8–17·5] of DALYs are risk attributable). Interpretation: Globally, the burden of neurological disorders, as measured by the absolute number of DALYs, continues to increase. As populations are growing and ageing, and the prevalence of major disabling neurological disorders steeply increases with age, governments will face increasing demand for treatment, rehabilitation, and support services for neurological disorders. The scarcity of established modifiable risks for most of the neurological burden demonstrates that new knowledge is required to develop effective prevention and treatment strategies. Funding: Bill & Melinda Gates Foundation. © 2019 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license
Published: 2019

9. Erratum: Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017 (The Lancet (2018) 392(10159) (1736–1788)(S0140673618322037)(10.1016/S0140-6736(18)32203-7))

Author: GBD 2017 Causes of Death Collaborators Roth, G.A. Abate, D. Abate, K.H. Abay, S.M. Abbafati, C. Abbasi, N. Abbastabar, H. Abd-Allah, F. Abdela, J. Abdelalim, A. Abdollahpour, I. Abdulkader, R.S. Abebe, H.T. Abebe, M. Abebe, Z. Abejie, A.N. Abera, S.F. Abil, O.Z. Abraha, H.N. Abrham, A.R. Abu-Raddad, L.J. Accrombessi, M.M.K. Acharya, D. Adamu, A.A. Adebayo, O.M. Adedoyin, R.A. Adekanmbi, V. Adetokunboh, O.O. Adhena, B.M. Adib, M.G. Admasie, A. Afshin, A. Agarwal, G. Agesa, K.M. Agrawal, A. Agrawal, S. Ahmadi, A. Ahmadi, M. Ahmed, M.B. Ahmed, S. Aichour, A.N. Aichour, I. Aichour, M.T.E. Akbari, M.E. Akinyemi, R.O. Akseer, N. Al-Aly, Z. Al-Eyadhy, A. Al-Raddadi, R.M. Alahdab, F. Alam, K. Alam, T. Alebel, A. Alene, K.A. Alijanzadeh, M. Alizadeh-Navaei, R. Aljunid, S.M. Alkerwi, A. Alla, F. Allebeck, P. Alonso, J. Altirkawi, K. Alvis-Guzman, N. Amare, A.T. Aminde, L.N. Amini, E. Ammar, W. Amoako, Y.A. Anber, N.H. Andrei, C.L. Androudi, S. Animut, M.D. Anjomshoa, M. Ansari, H. Ansha, M.G. Antonio, C.A.T. Anwari, P. Aremu, O. Arnlov, J. Arora, A. Arora, M. Artaman, A. Aryal, K.K. Asayesh, H. Asfaw, E.T. Ataro, Z. Atique, S. Atre, S.R. Ausloos, M. Avokpaho, E.F.G.A. Awasthi, A. Ayala Quintanilla, B.P. Ayele, Y. Ayer, R. Azzopardi, P.S. Babazadeh, A. Bacha, U. Badali, H. Badawi, A. Bali, A.G. Ballesteros, K.E. Banach, M. Banerjee, K. Bannick, M.S. Banoub, J.A.M. Barboza, M.A. Barker-Collo, S.L. Barnighausen, T.W. Barquera, S. Barrero, L.H. Bassat, Q. Basu, S. Baune, B.T. Baynes, H.W. Bazargan-Hejazi, S. Bedi, N. Beghi, E. Behzadifar, M. Behzadifar, M. Bejot, Y. Bekele, B.B. Belachew, A.B. Belay, E. Belay, Y.A. Bell, M.L. Bello, A.K. Bennett, D.A. Bensenor, I.M. Berman, A.E. Bernabe, E. Bernstein, R.S. Bertolacci, G.J. Beuran, M. Beyranvand, T. Bhalla, A. Bhattarai, S. Bhaumik, S. Bhutta, Z.A. Biadgo, B. Biehl, M.H. Bijani, A. Bikbov, B. Bilano, V. Bililign, N. Bin Sayeed, M.S. Bisanzio, D. Biswas, T. Blacker, B.F. Basara, B.B. Borschmann, R. Bosetti, C. Bozorgmehr, K. Brady, O.J. Brant, L.C. Brayne, C. Brazinova, A. Breitborde, N.J.K. Brenner, H. Briant, P.S. Britton, G. Brugha, T. Busse, R. Butt, Z.A. Callender, C.S.K.H. Campos-Nonato, I.R. Campuzano Rincon, J.C. Cano, J. Car, M. Cardenas, R. Carreras, G. Carrero, J.J. Carter, A. Carvalho, F. Castaneda-Orjuela, C.A. Castillo Rivas, J. Castle, C.D. Castro, C. Castro, F. Catala-Lopez, F. Cerin, E. Chaiah, Y. Chang, J.-C. Charlson, F.J. Chaturvedi, P. Chiang, P.P.-C. Chimed-Ochir, O. Chisumpa, V.H. Chitheer, A. Chowdhury, R. Christensen, H. Christopher, D.J. Chung, S.-C. Cicuttini, F.M. Ciobanu, L.G. Cirillo, M. Cohen, A.J. Cooper, L.T. Cortesi, P.A. Cortinovis, M. Cousin, E. Cowie, B.C. Criqui, M.H. Cromwell, E.A. Crowe, C.S. Crump, J.A. Cunningham, M. Daba, A.K. Dadi, A.F. Dandona, L. Dandona, R. Dang, A.K. Dargan, P.I. Daryani, A. Das, S.K. Gupta, R.D. Neves, J.D. Dasa, T.T. Dash, A.P. Davis, A.C. Davis Weaver, N. Davitoiu, D.V. Davletov, K. De La Hoz, F.P. De Neve, J.-W. Degefa, M.G. Degenhardt, L. Degfie, T.T. Deiparine, S. Demoz, G.T. Demtsu, B.B. Denova-Gutierrez, E. Deribe, K. Dervenis, N. Des Jarlais, D.C. Dessie, G.A. Dey, S. Dharmaratne, S.D. Dicker, D. Dinberu, M.T. Ding, E.L. Dirac, M.A. Djalalinia, S. Dokova, K. Doku, D.T. Donnelly, C.A. Dorsey, E.R. Doshi, P.P. Douwes-Schultz, D. Doyle, K.E. Driscoll, T.R. Dubey, M. Dubljanin, E. Duken, E.E. Duncan, B.B. Duraes, A.R. Ebrahimi, H. Ebrahimpour, S. Edessa, D. Edvardsson, D. Eggen, A.E. El Bcheraoui, C. El Sayed Zaki, M. El-Khatib, Z. Elkout, H. Ellingsen, C.L. Endres, M. Endries, A.Y. Er, B. Erskine, H.E. Eshrati, B. Eskandarieh, S. Esmaeili, R. Esteghamati, A. Fakhar, M. Fakhim, H. Faramarzi, M. Fareed, M. Farhadi, F. Farinha, C.S.E. Faro, A. Farvid, M.S. Farzadfar, F. Farzaei, M.H. Feigin, V.L. Feigl, A.B. Fentahun, N. Fereshtehnejad, S.-M. Fernandes, E. Fernandes, J.C. Ferrari, A.J. Feyissa, G.T. Filip, I. Finegold, S. Fischer, F. Fitzmaurice, C. Foigt, N.A. Foreman, K.J. Fornari, C. Frank, T.D. Fukumoto, T. Fuller, J.E. Fullman, N. Furst, T. Furtado, J.M. Futran, N.D. Gallus, S. Garcia-Basteiro, A.L. Garcia-Gordillo, M.A. Gardner, W.M. Gebre, A.K. Gebrehiwot, T.T. Gebremedhin, A.T. Gebremichael, B. Gebremichael, T.G. Gelano, T.F. Geleijnse, J.M. Genova-Maleras, R. Geramo, Y.C.D. Gething, P.W. Gezae, K.E. Ghadami, M.R. Ghadimi, R. Ghasemi Falavarjani, K. Ghasemi-Kasman, M. Ghimire, M. Gibney, K.B. Gill, P.S. Gill, T.K. Gillum, R.F. Ginawi, I.A. Giroud, M. Giussani, G. Goenka, S. Goldberg, E.M. Goli, S. Gomez-Dantes, H. Gona, P.N. Gopalani, S.V. Gorman, T.M. Goto, A. Goulart, A.C. Gnedovskaya, E.V. Grada, A. Grosso, G. Gugnani, H.C. Guimaraes, A.L.S. Guo, Y. Gupta, P.C. Gupta, R. Gupta, R. Gupta, T. Gutierrez, R.A. Gyawali, B. Haagsma, J.A. Hafezi-Nejad, N. Hagos, T.B. Hailegiyorgis, T.T. Hailu, G.B. Haj-Mirzaian, A. Haj-Mirzaian, A. Hamadeh, R.R. Hamidi, S. Handal, A.J. Hankey, G.J. Harb, H.L. Harikrishnan, S. Haro, J.M. Hasan, M. Hassankhani, H. Hassen, H.Y. 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Kazemi Karyani, A. Kazi, D.S. Kefale, A.T. Keiyoro, P.N. Kemp, G.R. Kengne, A.P. Keren, A. Kesavachandran, C.N. Khader, Y.S. Khafaei, B. Khafaie, M.A. Khajavi, A. Khalid, N. Khalil, I.A. Khan, E.A. Khan, M.S. Khan, M.A. Khang, Y.-H. Khater, M.M. Khoja, A.T. Khosravi, A. Khosravi, M.H. Khubchandani, J. Kiadaliri, A.A. Kibret, G.D. Kidanemariam, Z.T. Kiirithio, D.N. Kim, D. Kim, Y.-E. Kim, Y.J. Kimokoti, R.W. Kinfu, Y. Kisa, A. Kissimova-Skarbek, K. Kivimaki, M. Knudsen, A.K.S. Kocarnik, J.M. Kochhar, S. Kokubo, Y. Kolola, T. Kopec, J.A. Koul, P.A. Koyanagi, A. Kravchenko, M.A. Krishan, K. Kuate Defo, B. Kucuk Bicer, B. Kumar, G.A. Kumar, M. Kumar, P. Kutz, M.J. Kuzin, I. Kyu, H.H. Lad, D.P. Lad, S.D. Lafranconi, A. Lal, D.K. Lalloo, R. Lallukka, T. Lam, J.O. Lami, F.H. Lansingh, V.C. Lansky, S. Larson, H.J. Latifi, A. Lau, K.M.-M. Lazarus, J.V. Lebedev, G. Lee, P.H. Leigh, J. Leili, M. Leshargie, C.T. Li, S. Li, Y. Liang, J. Lim, L.-L. Lim, S.S. Limenih, M.A. Linn, S. Liu, S. Liu, Y. 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Abstract: GBD 2017 Causes of Death Collaborators. Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet 2018; 392: 1736–88—The bottom row in figure 7 was cut off. This correction has been made to the online version as of Nov 9, 2018, and has been made to the printed Article. © 2018 Elsevier Ltd
Published: 2018

10. Global, regional, and national age-sex-specific mortality and life expectancy, 1950-2017: A systematic analysis for the Global Burden of Disease Study 2017

Author: Dicker, D. Nguyen, G. Abate, D. Abate, K.H. Abay, S.M. Abbafati, C. Abbasi, N. Abbastabar, H. Abd-Allah, F. Abdela, J. Abdelalim, A. Abdel-Rahman, O. Abdi, A. Abdollahpour, I. Abdulkader, R.S. Abdurahman, A.A. Abebe, H.T. Abebe, M. Abebe, Z. Abebo, T.A. Aboyans, V. Abraha, H.N. Abrham, A.R. Abu-Raddad, L.J. Abu-Rmeileh, N.M.E. Accrombessi, M.M.K. Acharya, P. Adebayo, O.M. Adedeji, I.A. Adedoyin, R.A. Adekanmbi, V. Adetokunboh, O.O. Adhena, B.M. Adhikari, T.B. Adib, M.G. Adou, A.K. Adsuar, J.C. Afarideh, M. Afshin, A. Agarwal, G. Aggarwal, R. Aghayan, S.A. Agrawal, S. Agrawal, A. Ahmadi, M. Ahmadi, A. Ahmadieh, H. Ahmed, M.L.C.B. Ahmed, S. Ahmed, M.B. Aichour, A.N. Aichour, I. Aichour, M.T.E. Akanda, A.S. Akbari, M.E. Akibu, M. Akinyemi, R.O. Akinyemiju, T. Akseer, N. Alahdab, F. Al-Aly, Z. Alam, K. Alebel, A. Aleman, A.V. Alene, K.A. Al-Eyadhy, A. Ali, R. Alijanzadeh, M. Alizadeh-Navaei, R. Aljunid, S.M. Alkerwi, A. Alla, F. Allebeck, P. Allen, C.A. Alonso, J. Al-Raddadi, R.M. 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Eggen, A.E. El Bcheraoui, C. El Sayed Zaki, M. Elfaramawi, M. El-Khatib, Z. Ellingsen, C.L. Elyazar, I.R.F. Enayati, A. Endries, A.Y.Y. Er, B. Ermakov, S.P. Eshrati, B. Eskandarieh, S. Esmaeili, R. Esteghamati, A. Esteghamati, S. Fakhar, M. Fakhim, H. Farag, T. Faramarzi, M. Fareed, M. Farhadi, F. Farid, T.A. E SÃ¡ Farinha, C.S. Farioli, A. Faro, A. Farvid, M.S. Farzadfar, F. Farzaei, M.H. Fazeli, M.S. Feigin, V.L. Feigl, A.B. Feizy, F. Fentahun, N. Fereshtehnejad, S.-M. Fernandes, E. Fernandes, J.C. Feyissa, G.T. Fijabi, D.O. Filip, I. Finegold, S. Fischer, F. Flor, L.S. Foigt, N.A. Ford, J.A. Foreman, K.J. Fornari, C. Frank, T.D. Franklin, R.C. Fukumoto, T. Fuller, J.E. Fullman, N. FÃ¼rst, T. Furtado, J.M. Futran, N.D. Galan, A. Gallus, S. Gambashidze, K. Gamkrelidze, A. Gankpe, F.G. Garcia-Basteiro, A.L. Garcia-Gordillo, M.A. Gebre, T. Gebre, A.K. Gebregergs, G.B. Gebrehiwot, T.T. Gebremedhin, A.T. Gelano, T.F. Gelaw, Y.A. Geleijnse, J.M. Genova-Maleras, R. Gessner, B.D. 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Khafaie, M.A. Khajavi, A. Khalid, N. Khalil, I.A. Khan, E.A. Khan, G. Khan, M.S. Khan, M.A. Khang, Y.-H. Khanna, T. Khater, M.M. Khatony, A. Khazaie, H. Khoja, A.T. Khosravi, A. Khosravi, M.H. Khubchandani, J. Kiadaliri, A.A. Kibret, G.D.D. Kim, C.-I. Kim, D. Kim, J.Y. Kim, Y.-E. Kimokoti, R.W. Kinfu, Y. Kinra, S. Kisa, A. Kissimova-Skarbek, K. Kissoon, N. KivimÃ¤ki, M. Kleber, M.E. Knibbs, L.D. Knudsen, A.K.S. Kochhar, S. Kokubo, Y. Kolola, T. Kopec, J.A. Kosek, M.N. Kosen, S. Koul, P.A. Koyanagi, A. Kravchenko, M.A. Krishan, K. Krishnaswami, S. Kuate Defo, B. Kucuk Bicer, B. Kudom, A.A. Kuipers, E.J. Kulikoff, X.R. Kumar, G.A. Kumar, M. Kumar, P. Kumsa, F.A. Kutz, M.J. Lad, S.D. Lafranconi, A. Lal, D.K. Lalloo, R. Lam, H. Lami, F.H. Lan, Q. Langan, S.M. Lansingh, V.C. Lansky, S. Larson, H.J. Laryea, D.O. Lassi, Z.S. Latifi, A. Lavados, P.M. Laxmaiah, A. Lazarus, J.V. Lebedev, G. Lee, P.H. Leigh, J. Leshargie, C.T. Leta, S. Levi, M. Li, S. Li, Y. Li, X. Liang, J. Liang, X. Liben, M.L. Lim, L.-L. Lim, S.S. Limenih, M.A. Linn, S. Liu, S. Liu, Y. Lodha, R. Logroscino, G. Lonsdale, C. Lorch, S.A. Lorkowski, S. Lotufo, P.A. Lozano, R. Lucas, T.C.D. Lunevicius, R. Lyons, R.A. Ma, S. Mabika, C. Macarayan, E.R.K. Mackay, M.T. Maddison, E.R. Maddison, R. Madotto, F. Magdy Abd El Razek, H. Magdy Abd El Razek, M. Maghavani, D.P. Majdan, M. Majdzadeh, R. Majeed, A. Malekzadeh, R. Malik, M.A. Malta, D.C. Mamun, A.A. Manamo, W.A. Manda, A.-L. Mansournia, M.A. Mantovani, L.G. Mapoma, C.C. Marami, D. Maravilla, J.C. Marcenes, W. Marina, S. Martinez-Raga, J. Martins, S.C.O. Martins-Melo, F.R. MÃ¤rz, W. Marzan, M.B. Mashamba-Thompson, T.P. Masiye, F. Massenburg, B.B. Maulik, P.K. Mazidi, M. McGrath, J.J. McKee, M. Mehata, S. Mehendale, S.M. Mehndiratta, M.M. Mehrotra, R. Mehta, K.M. Mehta, V. Mekonen, T. Mekonnen, T.C. Meles, H.G. Meles, K.G. Melese, A. Melku, M. Memiah, P.T.N. Memish, Z.A. Mendoza, W. Mengistu, D.T. Mengistu, G. Mensah, G.A. Mereta, S.T. Meretoja, A. Meretoja, T.J. Mestrovic, T. Mezgebe, H.B. Miangotar, Y. Miazgowski, B. Miazgowski, T. Miller, T.R. Mini, G.K. Mirica, A. Mirrakhimov, E.M. Misganaw, A.T. Moazen, B. Moges, N.A. Mohammad, K.A. Mohammadi, M. Mohammadifard, N. Mohammadi-Khanaposhtani, M. Mohammadnia-Afrouzi, M. Mohammed, S. Mohammed, M.A. Mohan, V. Mokdad, A.H. Molokhia, M. Monasta, L. Moradi, G. Moradi, M. Moradi-Lakeh, M. Moradinazar, M. Moraga, P. Morawska, L. Moreno VelÃ¡squez, I. Morgado-Da-costa, J. Morrison, S.D. Mosapour, A. Moschos, M.M. Mousavi, S.M. Muche, A.A. Muchie, K.F. Mueller, U.O. Mukhopadhyay, S. Mullany, E.C. Muller, K. Murhekar, M. Murphy, T.B. Murthy, G.V.S. Murthy, S. Musa, J. Musa, K.I. Mustafa, G. Muthupandian, S. Nachega, J.B. Nagel, G. Naghavi, M. Naheed, A. Nahvijou, A. Naik, G. Nair, S. Najafi, F. Nangia, V. Nansseu, J.R. Nascimento, B.R. Nawaz, H. Ncama, B.P. Neamati, N. Negoi, I. Negoi, R.I. Neupane, S. Newton, C.R.J. Ngalesoni, F.N. Ngunjiri, J.W. Nguyen, H.T. Nguyen, H.T. Nguyen, L.H. Nguyen, M. Nguyen, T.H. Ningrum, D.N.A. Nirayo, Y.L. Nisar, M.I. Nixon, M.R. Nolutshungu, N. Nomura, S. Norheim, O.F. Noroozi, M. Norrving, B. Noubiap, J.J. Nouri, H.R. Nourollahpour Shiadeh, M. Nowroozi, M.R. Nsoesie, E.O. Nyasulu, P.S. Ofori-Asenso, R. Ogah, O.S. Ogbo, F.A. Oh, I.-H. Okoro, A. Oladimeji, O. Olagunju, A.T. Olagunju, T.O. Olivares, P.R. Olusanya, B.O. Olusanya, J.O. Ong, S.K. Opio, J.N. Oren, E. Ortiz, J.R. Ortiz, A. Ota, E. Otstavnov, S.S. Ã˜verland, S. Owolabi, M.O. Oyekale, A.S. Mahesh, P.A. Pacella, R. Pakhale, S. Pakhare, A.P. Pana, A. Panda, B.K. Panda-Jonas, S. Pandey, A.R. Pandian, J.D. Parisi, A. Park, E.-K. Parry, C.D.H. Parsian, H. Patel, S. Patle, A. Patten, S.B. Patton, G.C. Paudel, D. Pearce, N. Peprah, E.K. Pereira, A. Pereira, D.M. Perez, K.M. Perico, N. Pervaiz, A. Pesudovs, K. Petri, W.A. Petzold, M. Phillips, M.R. Pigott, D.M. Pillay, J.D. Pirsaheb, M. Pishgar, F. Plass, D. Polinder, S. Pond, C.D. Popova, S. Postma, M.J. Pourmalek, F. Pourshams, A. Poustchi, H. Prabhakaran, D. Prakash, V. Prakash, S. Prasad, N. Qorbani, M. Quistberg, D.A. Radfar, A. Rafay, A. Rafiei, A. Rahim, F. Rahimi, K. Rahimi-Movaghar, A. Rahimi-Movaghar, V. Rahman, M. Ur Rahman, M.H. Rahman, M.A. Ur Rahman, S. Rai, R.K. Rajati, F. Rajsic, S. Raju, S.B. Ram, U. Ranabhat, C.L. Ranjan, P. Ranta, A. Rasella, D. Rawaf, D.L. Rawaf, S. Ray, S.E. Razo-GarcÃa, C. Rego, M.A.S. Rehm, J. Reiner, R.C. Reinig, N. Reis, C. Remuzzi, G. Renzaho, A.M.N. Resnikoff, S. Rezaei, S. Rezaeian, S. Rezai, M.S. Riahi, S.M. Ribeiro, A.L.P. Riojas, H. Rios-Blancas, M.J. Roba, K.T. Robinson, S.R. Roever, L. Ronfani, L. Roshandel, G. Roshchin, D.O. Rostami, A. Rothenbacher, D. Rubagotti, E. Ruhago, G.M. Saadat, S. Sabde, Y.D. Sachdev, P.S. Saddik, B. Sadeghi, E. Saeedi Moghaddam, S. Safari, H. Safari, Y. Safari-Faramani, R. Safdarian, M. Safi, S. Safiri, S. Sagar, R. Sahebkar, A. Sahraian, M.A. Sajadi, H.S. Salahshoor, M. Salam, N. Salama, J.S. Salamati, P. Saldanha, R.F. Salimi, Y. Salimzadeh, H. Salz, I. Sambala, E.Z. Samy, A.M. Sanabria, J. Sanchez-NiÃ±o, M.D. Santos, I.S. Santos, J.V. Santric Milicevic, M.M. Sao Jose, B.P. Sardana, M. Sarker, A.R. Sarrafzadegan, N. Sartorius, B. Sarvi, S. Sathian, B. Satpathy, M. Savic, M. Sawant, A.R. Sawhney, M. Saxena, S. Sayyah, M. Scaria, V. Schaeffner, E. Schelonka, K. Schmidt, M.I. Schneider, I.J.C. SchÃ¶ttker, B. Schutte, A.E. Schwebel, D.C. Schwendicke, F. Scott, J.G. Sekerija, M. Sepanlou, S.G. ServÃ¡n-Mori, E. Shabaninejad, H. Shackelford, K.A. Shafieesabet, A. Shaheen, A.A. Shaikh, M.A. Shakir, R.A. Shams-Beyranvand, M. Shamsi, M. Shamsizadeh, M. Sharafi, H. Sharafi, K. Sharif, M. Sharif-Alhoseini, M. Sharma, M. Sharma, J. Sharma, R. She, J. Sheikh, A. Sheth, K.N. Shi, P. Shibuya, K. Shifa, G.T. Shiferaw, M.S. Shigematsu, M. Shiri, R. Shirkoohi, R. Shiue, I. Shokraneh, F. Shrime, M.G. Shukla, S.R. Si, S. Siabani, S. Siddiqi, T.J. Sigfusdottir, I.D. Sigurvinsdottir, R. Silpakit, N. Silva, D.A.S. Silva, J.P. Silveira, D.G.A. Singam, N.S.V. Singh, J.A. Singh, V. Sinha, A.P. Sinha, D.N. Sitas, F. Skirbekk, V. Sliwa, K. Soares Filho, A.M. Sobaih, B.H. Sobhani, S. Soofi, M. Soriano, J.B. Soyiri, I.N. Sposato, L.A. Sreeramareddy, C.T. Srinivasan, V. Srivastava, R.K. Starodubov, V.I. Stathopoulou, V. Steel, N. Stein, D.J. Steiner, C. Stewart, L.G. Stokes, M.A. Sudaryanto, A. Sufiyan, M.B. Sulo, G. Sunguya, B.F. Sur, P.J. Sutradhar, I. Sykes, B.L. Sylaja, P.N. Sylte, D.O. Szoeke, C.E.I. TabarÃ©s-Seisdedos, R. Tabuchi, T. Tadakamadla, S.K. Takahashi, K. Tandon, N. Tassew, A.A. Tassew, S.G. Tavakkoli, M. Taveira, N. Tawye, N.Y. Tehrani-Banihashemi, A. Tekalign, T.G. Tekle, M.G. Temesgen, H. Temsah, M.-H. Temsah, O. Terkawi, A.S. Teshale, M.Y. Tessema, B. Teweldemedhin, M. Thakur, J.S. Thankappan, K.R. Thirunavukkarasu, S. Thomas, L.A. Thomas, N. Thrift, A.G. Tilahun, B. To, Q.G. Tobe-Gai, R. Tonelli, M. Topor-Madry, R. Topouzis, F. Torre, A.E. Tortajada-GirbÃ©s, M. Tovani-Palone, M.R. Towbin, J.A. Tran, B.X. Tran, K.B. Tripathi, S. Tripathy, S.P. Truelsen, T.C. Truong, N.T. Tsadik, A.G. Tsilimparis, N. Tudor Car, L. Tuzcu, E.M. Tyrovolas, S. Ukwaja, K.N. Ullah, I. Usman, M.S. Uthman, O.A. Uzun, S.B. Vaduganathan, M. Vaezi, A. Vaidya, G. Valdez, P.R. Varavikova, E. Varughese, S. Vasankari, T.J. Vasconcelos, A.M.N. Venketasubramanian, N. Vidavalur, R. Villafaina, S. Violante, F.S. Vladimirov, S.K. Vlassov, V. Vollset, S.E. Vos, T. Vosoughi, K. Vujcic, I.S. Wagner, G.R. Wagnew, F.W.S. Waheed, Y. Wang, Y. Wang, Y.-P. Wassie, M.M. Weiderpass, E. Weintraub, R.G. Weiss, D.J. Weiss, J. Weldegebreal, F. Weldegwergs, K.G. Werdecker, A. Westerman, R. Whiteford, H.A. Widecka, J. Widecka, K. Wijeratne, T. Winkler, A.S. Wiysonge, C.S. Wolfe, C.D.A. Wondemagegn, S.A. Wu, S. Wyper, G.M.A. Xu, G. Yadav, R. Yakob, B. Yamada, T. Yan, L.L. Yano, Y. Yaseri, M. Yasin, Y.J. Ye, P. Yearwood, J.A. YentÃ¼r, G.K. Yeshaneh, A. Yimer, E.M. Yip, P. Yisma, E. Yonemoto, N. Yoon, S.-J. York, H.W. Yotebieng, M. Younis, M.Z. Yousefifard, M. Yu, C. Zachariah, G. Zadnik, V. Zafar, S. Zaidi, Z. Zaman, S.B. Zamani, M. Zare, Z. Zeeb, H. Zeleke, M.M. Zenebe, Z.M. Zerfu, T.A. Zhang, K. Zhang, X. Zhou, M. Zhu, J. Zodpey, S. Zucker, I. Zuhlke, L.J.J. Lopez, A.D. Gakidou, E. Murray, C.J.L. GBD 2017 Mortality Collaborators
Abstract: Background: Assessments of age-specifc mortality and life expectancy have been done by the UN Population Division, Department of Economics and Social Afairs (UNPOP), the United States Census Bureau, WHO, and as part of previous iterations of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD). Previous iterations of the GBD used population estimates from UNPOP, which were not derived in a way that was internally consistent with the estimates of the numbers of deaths in the GBD. The present iteration of the GBD, GBD 2017, improves on previous assessments and provides timely estimates of the mortality experience of populations globally. Methods: The GBD uses all available data to produce estimates of mortality rates between 1950 and 2017 for 23 age groups, both sexes, and 918 locations, including 195 countries and territories and subnational locations for 16 countries. Data used include vital registration systems, sample registration systems, household surveys (complete birth histories, summary birth histories, sibling histories), censuses (summary birth histories, household deaths), and Demographic Surveillance Sites. In total, this analysis used 8259 data sources. Estimates of the probability of death between birth and the age of 5 years and between ages 15 and 60 years are generated and then input into a model life table system to produce complete life tables for all locations and years. Fatal discontinuities and mortality due to HIV/AIDS are analysed separately and then incorporated into the estimation. We analyse the relationship between age-specifc mortality and development status using the Socio-demographic Index, a composite measure based on fertility under the age of 25 years, education, and income. There are four main methodological improvements in GBD 2017 compared with GBD 2016: 622 additional data sources have been incorporated; new estimates of population, generated by the GBD study, are used; statistical methods used in diferent components of the analysis have been further standardised and improved; and the analysis has been extended backwards in time by two decades to start in 1950. Findings: Globally, 18·7% (95% uncertainty interval 18·4-19·0) of deaths were registered in 1950 and that proportion has been steadily increasing since, with 58·8% (58·2-59·3) of all deaths being registered in 2015. At the global level, between 1950 and 2017, life expectancy increased from 48·1 years (46·5-49·6) to 70·5 years (70·1-70·8) for men and from 52·9 years (51·7-54·0) to 75·6 years (75·3-75·9) for women. Despite this overall progress, there remains substantial variation in life expectancy at birth in 2017, which ranges from 49·1 years (46·5-51·7) for men in the Central African Republic to 87·6 years (86·9-88·1) among women in Singapore. The greatest progress across age groups was for children younger than 5 years; under-5 mortality dropped from 216·0 deaths (196·3-238·1) per 1000 livebirths in 1950 to 38·9 deaths (35·6-42·83) per 1000 livebirths in 2017, with huge reductions across countries. Nevertheless, there were still 5·4 million (5·2-5·6) deaths among children younger than 5 years in the world in 2017. Progress has been less pronounced and more variable for adults, especially for adult males, who had stagnant or increasing mortality rates in several countries. The gap between male and female life expectancy between 1950 and 2017, while relatively stable at the global level, shows distinctive patterns across super-regions and has consistently been the largest in central Europe, eastern Europe, and central Asia, and smallest in south Asia. Performance was also variable across countries and time in observed mortality rates compared with those expected on the basis of development. Interpretation: This analysis of age-sex-specifc mortality shows that there are remarkably complex patterns in population mortality across countries. The fndings of this study highlight global successes, such as the large decline in under-5 mortality, which refects signifcant local, national, and global commitment and investment over several decades. However, they also bring attention to mortality patterns that are a cause for concern, particularly among adult men and, to a lesser extent, women, whose mortality rates have stagnated in many countries over the time period of this study, and in some cases are increasing. © 2018 The Author(s).
Published: 2018

11. Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017

Author: Lozano, R. Fullman, N. Abate, D. Abay, S.M. Abbafati, C. Abbasi, N. Abbastabar, H. Abd-Allah, F. Abdela, J. Abdelalim, A. Abdel-Rahman, O. Abdi, A. Abdollahpour, I. Abdulkader, R.S. Abebe, N.D. Abebe, Z. Abejie, A.N. Abera, S.F. Abil, O.Z. Aboyans, V. Abraha, H.N. Abrham, A.R. Abu-Raddad, L.J. Abu-Rmeileh, N.M. Abyu, G.Y. Accrombessi, M.M.K. Acharya, D. Acharya, P. Adamu, A.A. Adebayo, O.M. Adedeji, I.A. Adedoyin, R.A. Adekanmbi, V. Adetokunboh, O.O. Adhena, B.M. Adhikari, T.B. Adib, M.G. Adou, A.K. Adsuar, J.C. Afarideh, M. Afshari, M. Afshin, A. Agarwal, G. Aghayan, S.A. Agius, D. Agrawal, A. Agrawal, S. Ahmadi, A. Ahmadi, M. Ahmadieh, H. Ahmed, M.B. Ahmed, S. Akalu, T.Y. Akanda, A.S. Akbari, M.E. Akibu, M. Akinyemi, R.O. Akinyemiju, T. Akseer, N. Alahdab, F. Al-Aly, Z. Alam, K. Alam, T. Albujeer, A. Alebel, A. Alene, K.A. Al-Eyadhy, A. Alhabib, S. Ali, R. Alijanzadeh, M. Alizadeh-Navaei, R. Aljunid, S.M. Alkerwi, A. Alla, F. Allebeck, P. Allen, C.A. Almasi, A. Al-Maskari, F. Al-Mekhlafi, H.M. Alonso, J. Al-Raddadi, R.M. Alsharif, U. Altirkawi, K. Alvis-Guzman, N. Amare, A.T. Amenu, K. Amini, E. Ammar, W. Anber, N.H. Anderson, J.A. Andrei, C.L. Androudi, S. Animut, M.D. Anjomshoa, M. Ansari, H. Ansariadi, A. Ansha, M.G. Antonio, C.A.T. Anwari, P. Appiah, L.T. Aremu, O. Areri, H.A. Ärnlöv, J. Arora, M. Aryal, K.K. Asayesh, H. Asfaw, E.T. Asgedom, S.W. Asghar, R.J. Assadi, R. Ataro, Z. Atique, S. Atre, S.R. Atteraya, M.S. Ausloos, M. Avila-Burgos, L. Avokpaho, E.F.G.A. Awasthi, A. Quintanilla, B.P.A. Ayele, H.T. Ayele, Y. Ayer, R. Azarpazhooh, M.R. Azzopardi, P.S. Azzopardi-Muscat, N. Babalola, T.K. Babazadeh, A. Badali, H. Badawi, A. Balakrishnan, K. Bali, A.G. Banach, M. Banerjee, A. Banoub, J.A.M. Banstola, A. Barac, A. Barboza, M.A. Barker-Collo, S.L. Bärnighausen, T.W. Barrero, L.H. Barthelemy, C.M. Bassat, Q. Basu, A. Basu, S. Battista, R.J. Baune, B.T. Baynes, H.W. Bazargan-Hejazi, S. Bedi, N. Beghi, E. Behzadifar, M. Behzadifar, M. Béjot, Y. Bekele, B.B. Belachew, A.B. Belay, A.G. Belay, S.A. Belay, Y.A. Bell, M.L. Bello, A.K. Bennett, D.A. Bensenor, I.M. Benzian, H. Berhane, A. Berhe, A.K. Berman, A.E. Bernabe, E. Bernstein, R.S. Bertolacci, G.J. Beuran, M. Beyranvand, T. Bhala, N. Bhalla, A. Bhansali, A. Bhattarai, S. Bhaumik, S. Bhutta, Z.A. Biadgo, B. Biehl, M.H. Bijani, A. Bikbov, B. Bililign, N. Sayeed, M.S.B. Birlik, S.M. Birungi, C. Bisanzio, D. Biswas, T. Bitew, H. Bizuneh, H. Bjertness, E. Bobasa, E.M. Boufous, S. Bourne, R. Bozorgmehr, K. Bragazzi, N.L. Brainin, M. Brant, L.C. Brauer, M. Brazinova, A. Breitborde, N.J.K. Briant, P.S. Britton, G. Brugha, T. Bukhman, G. Busse, R. Butt, Z.A. Cahuana-Hurtado, L. Callender, C.S.K.H. Campos-Nonato, I.R. Rincon, J.C.C. Cano, J. Car, J. Car, M. Cárdenas, R. Carrero, J.J. Carter, A. Carvalho, F. Castañeda-Orjuela, C.A. Rivas, J.C. Castro, F. Causey, K. Çavlin, A. Cercy, K.M. Cerin, E. Chaiah, Y. Chalek, J. Chang, H.-Y. Chang, J.-C. Chattopadhyay, A. Chattu, V.K. Chaturvedi, P. Chiang, P.P.-C. Chin, K.L. Chisumpa, V.H. Chitheer, A. Choi, J.-Y.J. Chowdhury, R. Christensen, H. Christopher, D.J. Chung, S.-C. Cicuttini, F.M. Ciobanu, L.G. Cirillo, M. Claro, R.M. Claßen, T.K.D. Cohen, A.J. Collado-Mateo, D. Cooper, C. Cooper, L.T. Cornaby, L. Cortinovis, M. Costa, M. Cousin, E. Cromwell, E.A. Crowe, C.S. Cunningham, M. Daba, A.K. Dadi, A.F. Dandona, L. Dandona, R. Dang, A.K. Dargan, P.I. Daryani, A. Das, S.K. Das Gupta, R. Das Neves, J. Dasa, T.T. Dash, A.P. Davis, A.C. Davitoiu, D.V. Davletov, K. Dayama, A. De Courten, B. De Leo, D. Neve, J.W.D. De Steur, H. Degefa, M.G. Degenhardt, L. Degfie, T.T. Deiparine, S. Dellavalle, R.P. Demoz, G.T. Demtsu, B. Denova-Gutiérrez, E. Deribe, K. Dervenis, N. Dessie, G.A. Dey, S. Dharmaratne, S.D. Dhimal, M. Dicker, D. Dinberu, M.T. Ding, E.L. Djalalinia, S. Do, H.P. Dokova, K. Doku, D.T. Douwes-Schultz, D. Driscoll, T.R. Duan, L. Dubey, M. Dubljanin, E. Duken, E.E. Duncan, B.B. Duraes, A.R. Ebrahimpour, S. Edvardsson, D. El Bcheraoui, C. Eldrenkamp, E. El-Khatib, Z. Elyazar, I.R.F. Enayati, A. Endries, A.Y. Eshrati, B. Eskandarieh, S. Esteghamati, A. Esteghamati, S. Estep, K. Fakhar, M. Fakhim, H. Fanzo, J. Faramarzi, M. Fareed, M. Farhadi, F. Farid, T.A. Farinha, C.S.E.S. Farioli, A. Faro, A. Farvid, M.S. Farzadfar, F. Farzaei, M.H. Farzam, H. Fazaeli, A.A. Fazeli, M.S. Feigin, V.L. Feigl, A.B. Fekadu, W. Feldman, R. Fentahun, N. Fereshtehnejad, S.-M. Fernandes, E. Fernandes, J.C. Feyissa, G.T. Fijabi, D.O. Filip, I. Finegold, S. Finger, J.D. Fischer, F. Fitzmaurice, C. Flor, L.S. Foigt, N.A. Foreman, K.J. Frank, T.D. Franklin, R.C. Fukumoto, T. Fukutaki, K. Fuller, J.E. Fürst, T. Furtado, J.M. Gakidou, E. Gallus, S. Gankpe, F.G. Gansevoort, R.T. Garcia, A.C. Garcia-Basteiro, A.L. Garcia-Gordillo, M.A. Gardner, W.M. Gebre, A.K. Gebre, T. Gebregergs, G.B. Gebrehiwot, T.T. Gebremedhin, A.T. Gebremichael, B. Gebremichael, T.G. Gelano, T.F. Geleijnse, J.M. Geramo, Y.C.D. Getachew, S. Gething, P.W. Gezae, K.E. Ghadami, M.R. Ghadimi, R. Ghadiri, K. Ghasemi-Kasman, M. Ghiasvand, H. Ghimire, M. Ghoshal, A.G. Giampaoli, S. Gill, P.S. Gill, T.K. Giussani, G. Gnedovskaya, E.V. Goldberg, E.M. Goli, S. Gona, P.N. Goodridge, A. Gopalani, S.V. Gorman, T.M. Goto, A. Goulart, A.C. Goulart, B.N.G. Grada, A. Griswold, M.G. Grosso, G. Gugnani, H.C.C. Guillemin, F. Guimaraes, A.L.S. Guo, Y. Gupta, P.C. Gupta, R. Gupta, R. Gupta, T. Ha, G.H. Haagsma, J.A. Hachinski, V. Hafezi-Nejad, N. Bidgoli, H.H. Hagos, T.B. Haile, M.T. Hailegiyorgis, T.T. Hailu, G.B. Haj-Mirzaian, A. Haj-Mirzaian, A. Hamadeh, R.R. Hamidi, S. Hankey, G.J. Harb, H.L. Harikrishnan, S. Haririan, H. Haro, J.M. Hasan, M. Hassankhani, H. Hassen, H.Y. Havmoeller, R. Hawley, C.N. Hay, S.I. He, Y. Hedayatizadeh-Omran, A. Hegazy, M.I. Heibati, B. Heidari, B. Heidari, M. Hendrie, D. Henok, A. Heredia-Pi, I. Herteliu, C. Heydarpour, B. Heydarpour, F. Heydarpour, S. Hibstu, D.T. Híjar, M. Hoek, H.W. Hoffman, D.J. Hole, M.K. Homaie Rad, E. Hoogar, P. Horita, N. Hosgood, H.D. Hosseini, S.M. Hosseinzadeh, M. Hostiuc, M. Hostiuc, S. Hotez, P.J. Hoy, D.G. Hsairi, M. Hsiao, T. Hu, G. Huang, J.J. Hughes, C. Huynh, C.K. Igumbor, E.U. Ikeda, C.T. Ilesanmi, O.S. Iqbal, U. Irvani, S.S.N. Irvine, C.M.S. Islam, S.M.S. Islami, F. Ivers, R.Q. Izadi, N. Jacobsen, K.H. Jahangiry, L. Jahanmehr, N. Jain, S.K. Jakovljevic, M. Jalu, M.T. Jamal, A.A. James, S.L. Jassal, S.K. Javanbakht, M. Jayatilleke, A.U. Jeemon, P. Jha, R.P. Jha, V. Ji, J.S. Johnson, C.O. Johnson, S.C. Jonas, J.B. Jonnagaddala, J. Shushtari, Z.J. Joshi, A. Jozwiak, J.J. Jungari, S.B. Jürisson, M. Madhanraj, K. Kabir, Z. Kadel, R. Kahsay, A. Kahssay, M. Kalani, R. Kapil, U. Karami, M. Matin, B.K. Karanikolos, M. Karimi, N. Karimi, S.M. Karimi-Sari, H. Kasaeian, A. Kassa, D.H. Kassa, G.M. Kassa, T.D. Kassa, Z.Y. Kassebaum, N.J. Katikireddi, S.V. Kaul, A. Kawakami, N. Kazemi, Z. Karyani, A.K. Kazi, D.S. Prakash, K.C. Kebede, S. Keiyoro, P.N. Kemmer, L. Kemp, G.R. Kengne, A.P. Keren, A. Kesavachandran, C.N. Khader, Y.S. Khafaei, B. Khafaie, M.A. Khajavi, A. Khalid, N. Khalil, I.A. Khan, E.A. Khan, M.S. Khan, M.A. Khang, Y.-H. Khanna, T. Khater, M.M. Khatony, A. Khazaeipour, Z. Khazaie, H. Khoja, A.T. Khosravi, A. Khosravi, M.H. Khubchandani, J. Kiadaliri, A.A. Kiarie, H.W. Kibret, G.D. Kiirithio, D.N. Kim, D. Kim, J.Y. Kim, Y.-E. Kim, Y.J. Kimokoti, R.W. Kinfu, Y. Kinra, S. Kisa, A. Kissimova-Skarbek, K. Kissoon, N. Kivimäki, M. Kocarnik, J.M. Kochhar, S. Kokubo, Y. Kolola, T. Kopec, J.A. Kosek, M.N. Kosen, S. Koul, P.A. Koyanagi, A. Kravchenko, M.A. Krishan, K. Krohn, K.J. Defo, B.K. Kucuk Bicer, B. Kudom, A.A. Kulikoff, X.R. Kumar, G.A. Kumar, M. Kumar, P. Kutz, M.J. Kyu, H.H. Lachat, C. Lad, D.P. Lad, S.D. Lafranconi, A. Lagat, A.K. Lal, D.K. Lalloo, R. Lam, H. Lami, F.H. Lamichhane, P. Lan, Q. Lang, J.J. Lansingh, V.C. Lansky, S. Larson, H.J. Larsson, A.O. Laryea, D.O. Lassi, Z.S. Latifi, A. Lau, K.M.-M. Laxmaiah, A. Lazarus, J.V. Leasher, J.L. Lebedev, G. Ledesma, J.R. Lee, J.B. Lee, P.H. Leever, A.T. Leigh, J. Leinsalu, M. Leshargie, C.T. Leung, J. Lewycka, S. Li, S. Li, X. Li, Y. Liang, J. Liang, X. Liben, M.L. Lim, L.-L. Limenih, M.A. Linn, S. Liu, S. Liu, Y. Lodha, R. Logroscino, G. Lopez, A.D. Lorkowski, S. Lotufo, P.A. Lucchesi, L.R. Lyons, R.A. Macarayan, E.R.K. Mackay, M.T. Maddison, E.R. Madotto, F. Maghavani, D.P. Magis-Rodriguez, C. Mahotra, N.B. Majdan, M. Majdzadeh, R. Majeed, A. Malekzadeh, R. Malta, D.C. Mamun, A.A. Manda, A.-L. Mandarano-Filho, L.G. Mangalam, S. Manguerra, H. Mansournia, M.A. Mapoma, C.C. Maravilla, J.C. Marcenes, W. Marks, A. Martin, R.V. Martins, S.C.O. Martins-Melo, F.R. Martopullo, I. Mashamba-Thompson, T.P. Massenburg, B.B. Mathur, M.R. Maulik, P.K. Mazidi, M. McAlinden, C. McGrath, J.J. McKee, M. McMahon, B.J. Mehata, S. Mehndiratta, M.M. Mehrotra, R. Mehta, K.M. Mehta, V. Mejia-Rodriguez, F. Mekonen, T. Mekonnen, T.C.C. Meles, H.G. Melese, A. Melku, M. Memiah, P.T.N. Memish, Z.A. Mendoza, W. Mengistu, D.T. Mengistu, G. Mensah, G.A. Mensink, G.B.M. Mereta, S.T. Meretoja, A. Meretoja, T.J. Mestrovic, T. Mezgebe, H.B. Miazgowski, B. Miazgowski, T. Millear, A.I. Miller, T.R. Miller-Petrie, M.K. Milne, G.J. Mini, G.K. Minnig, S.P. Mirabi, P. Mirarefin, M. Mirrakhimov, E.M. Misganaw, A.T. Mitchell, P.B. Moazen, B. Moghadamnia, A.A. Mohajer, B. Mohammad, K.A. Mohammadi, M. Mohammadifard, N. Mohammadnia-Afrouzi, M. Mohammed, M.A. Mohammed, S. Mohan, M.B.V. Mohan, V. Mohebi, F. Moitra, M. Mokdad, A.H. Molokhia, M. Monasta, L. Montañez, J.C. Moosazadeh, M. Moradi, G. Moradi, M. Moradi-Lakeh, M. Moradinazar, M. Moraga, P. Morawska, L. Morgado-da-Costa, J. Morisaki, N. Morrison, S.D. Mosapour, A. Moschos, M.M. Mountjoy-Venning, W.C. Mouodi, S. Mousavi, S.M. Muche, A.A. Muchie, K.F. Mueller, U.O. Muhammed, O.S.S. Mukhopadhyay, S. Mullany, E.C. Muller, K. Mumford, J.E. Murhekar, M. Murthy, G.V.S. Murthy, S. Musa, J. Musa, K.I. Mustafa, G. Muthupandian, S. Nabhan, A.F. Nachega, J.B. Nagarajan, A.J. Nagel, G. Naghavi, M. Naheed, A. Nahvijou, A. Naidoo, K. Naik, G. Naik, N. Najafi, F. Naldi, L. Nam, H.S. Nangia, V. Nansseu, J.R. Nascimento, B.R. Nawaz, H. Neamati, N. Negoi, I. Negoi, R.I. Neupane, S. Newton, C.R.J. Ngalesoni, F.N. Ngunjiri, J.W. Nguyen, A. Nguyen, G. Nguyen, H. Nguyen, H.L.T. Nguyen, H.T. Nguyen, M. Nichols, E. Nigatu, S.G. Ningrum, D.N.A. Nirayo, Y.L. Nisar, M.I. Nixon, M.R. Nolutshungu, N. Nomura, M. Norheim, O.F. Noroozi, M. Norrving, B. Noubiap, J.J. Nouri, H.R. Shiadeh, M.N. Nowroozi, M.R. Nyasulu, P.S. Obermeyer, C.M. Ofori-Asenso, R. Ogah, O.S. Ogbo, F.A. Oh, I.-H. Okoro, A. Oladimeji, K.E. Oladimeji, O. Olagunju, A.T. Olagunju, T.O. Olivares, P.R. Olsen, H.E. Olusanya, B.O. Olusanya, J.O. Ong, K.L. Ong, S.K. Oommen, A.M. Opio, J.N. Oren, E. Oros, A. Ortega-Altamirano, D.D.V. Ortiz, A. Ortiz, J.R. Ortiz-Panozo, E. Ota, E. Otstavnov, S.S. Owolabi, M.O. Mahesh, P.A. Pakhale, S. Pakhare, A.P. Pan, W.-H. Pana, A. Panda, B.K. Panda-Jonas, S. Pandian, J.D. Papantoniou, N. Park, E.-K. Parry, C.D.H. Parsian, H. Patel, S. Pati, S. Patle, A. Patton, G.C. Paturi, V.R. Paudel, D. Paulson, K.R. Pearce, N. Peprah, E.K. Pereira, D.M. Perico, N. Pervaiz, A. Pesudovs, K. Petri, W.A. Petzold, M. Phillips, M.R. Pigott, D.M. Pillay, J.D. Pirsaheb, M. Pletcher, M. Pond, C.D. Postma, M.J. Pourshams, A. Poustchi, H. Prabhakaran, D. Prakash, S. Prasad, N. Purcell, C.A. Pyakurel, M. Qorbani, M. Quansah, R. Radfar, A. Rafay, A. Rafiei, A. Rahim, F. Rahimi, K. Rahimi-Movaghar, A. Rahimi-Movaghar, V. Rahman, M. Rahman, M.S. Rahman, M.H.U. Rahman, M.A. Rahman, S.U. Rai, R.K. Rajati, F. Rajsic, S. Ram, U. Rana, S.M. Ranabhat, C.L. Ranjan, P. Rasella, D. Rawaf, D.L. Rawaf, S. Razo-García, C. Reddy, K.S. Reiner, R.C. Reis, C. Reitsma, M.B. Remuzzi, G. Renzaho, A.M.N. Resnikoff, S. Reynales-Shigematsu, L.M. Rezaei, S. Rezaeian, S. Rezai, M.S. Riahi, S.M. Ribeiro, A.L.P. Rios-Blancas, M.J. Roba, K.T. Roberts, N.L.S. Roever, L. Ronfani, L. Roshandel, G. Rostami, A. Roth, G.A. Roy, A. Rubagotti, E. Ruhago, G.M. Sabde, Y.D. Sachdev, P.S. Saddik, B. Sadeghi, E. Safari, H. Safari, Y. Safari-Faramani, R. Safdarian, M. Safi, S. Safiri, S. Sagar, R. Sahebkar, A. Sahraian, M.A. Sajadi, H.S. Salam, N. Salama, J.S. Salamati, P. De Freitas Saldanha, R. Saleem, Z. Salimi, Y. Salimzadeh, H. Salomon, J.A. Salvi, S.S. Salz, I. Sambala, E.Z. Samy, A.M. Sanabria, J. Sanchez-Niño, M.D. Santos, I.S. Milicevic, M.M.S. Jose, B.P.S. Sardana, M. Sarker, A.R. Sarrafzadegan, N. Sartorius, B. Sarvi, S. Sathian, B. Satpathy, M. Savic, M. Sawant, A.R. Sawhney, M. Saxena, S. Saylan, M. Sayyah, M. Schaeffner, E. Schmidt, M.I. Schneider, I.J.C. Schöttker, B. Schutte, A.E. Schwebel, D.C. Schwendicke, F. Seedat, S. Sekerija, M. Sepanlou, S.G. Serván-Mori, E. Seyedmousavi, S. Shabaninejad, H. Shackelford, K.A. Shafieesabet, A. Shaheen, A.A. Shaikh, M.A. Shams-Beyranvand, M. Shamsi, M.B. Shamsizadeh, M. Sharafi, H. Sharafi, K. Sharif, M. Sharif-Alhoseini, M. Sharma, J. Sharma, R. Sharma, S.K. She, J. Sheikh, A. Shey, M.S. Shi, P. Shibuya, K. Shields, C. Shifa, G.T. Shiferaw, M.S. Shigematsu, M. Shiri, R. Shirkoohi, R. Shirude, S. Shishani, K. Shiue, I. Shokraneh, F. Shoman, H. Shrime, M.G. Shukla, S.R. Si, S. Siabani, S. Sibai, A.M. Siddiqi, T.J. Sigfusdottir, I.D. Silpakit, N. Silva, D.A.S. Silva, J.P. Da Silva, N.T. Silveira, D.G.A. Singh, J.A. Singh, N.P. Singh, O.P. Singh, P.K. Singh, V. Sinha, D.N. Skiadaresi, E. Sliwa, K. Smith, A.E. Smith, M. Filho, A.M.S. Sobaih, B.H. Sobhani, S. Soljak, M. Soofi, M. Soosaraei, M. Sorensen, R.J.D. Soriano, J.B. Soshnikov, S. Soyiri, I.N. Spinelli, A. Sposato, L.A. Sreeramareddy, C.T. Srinivasan, R.G. Srinivasan, V. Stanaway, J.D. Starodubov, V.I. Stathopoulou, V. Steckling, N. Stein, D.J. Stewart, L.G. Stockfelt, L. Stokes, M.A. Straif, K. Sudaryanto, A. Sufiyan, M.B. Sunguya, B.F. Sur, P.J. Sutradhar, I. Sykes, B.L. Sylaja, P.N. Sylte, D.O. Szoeke, C.E.I. Tabarés-Seisdedos, R. Tabuchi, T. Tadakamadla, S.K. Tamirat, K.S. Tandon, N. Tanser, F.C. Tassew, A.A. Tassew, S.G. Tavakkoli, M. Taveira, N. Tawye, N.Y. Tehrani-Banihashemi, A. Tekalign, T.G. Tekle, M.G. Temesgen, H. Temsah, M.-H. Temsah, O. Terkawi, A.S. Teshale, M.Y. Teshome, D.F. Tessema, B. Teweldemedhin, M. Thakur, J.S. Thankappan, K.R. Theis, A. Thirunavukkarasu, S. Thomas, L.A. Thomas, N. Thomson, A.J. Thrift, A.G. Tilahun, B. To, Q.G. Tobe-Gai, R. Tonelli, M. Topor-Madry, R. Torre, A.E. Tortajada-Girbés, M. Tovani-Palone, M.R. Towbin, J.A. Tran, B.X. Tran, K.B. Tran, T.T. Tripathy, S.P. Troeger, C.E. Truelsen, T.C. Tsadik, A.G. Car, L.T. Tuzcu, E.M. Tymeson, H.D. Ukwaja, K.N. Ullah, I. Updike, R.L. Usman, M.S. Uthman, O.A. Vaduganathan, M. Vaezi, A. Vaidya, G. Valdez, P.R. Van Donkelaar, A. Varavikova, E. Vasankari, T.J. Venketasubramanian, N. Vidavalur, R. Villafaina, S. Violante, F.S. Vladimirov, S.K. Vlassov, V. Vollmer, S. Vollset, S.E. Vos, T. Vosoughi, K. Vujcic, I.S. Wagner, G.R. Wagnew, F.S. Waheed, Y. Walson, J.L. Wang, Y. Wang, Y.-P. Wassie, M.M. Weiderpass, E. Weintraub, R.G. Weiss, J. Weldegebreal, F. Weldegwergs, K.G. Werdecker, A. Werkneh, A.A. West, T.E. Westerman, R. Whisnant, J.L. Whiteford, H.A. Widecka, J. Widecka, K. Wijeratne, T. Wilner, L.B. Winkler, A.S. Wiyeh, A.B. Wiysonge, C.S. Wolde, H.F. Wolfe, C.D.A. Wu, S. Xavier, D. Xu, G. Xu, R. Yadollahpour, A. Jabbari, S.H.Y. Yakob, B. Yamada, T. Yan, L.L. Yano, Y. Yaseri, M. Yasin, Y.J. Ye, P. Yearwood, J.A. Yeshaneh, A. Yimer, E.M. Yip, P. Yirsaw, B.D. Yisma, E. Yonemoto, N. Yonga, G. Yoon, S.-J. Yotebieng, M. Younis, M.Z. Yousefifard, M. Yu, C. Zaman, S.B. Zamani, M. Zare, Z. Zavala-Arciniega, L. Zegeye, D.T. Zegeye, E.A. Zeleke, A.J. Zendehdel, K. Zerfu, T.A. Zhang, A.L. Zhang, X. Zhou, M. Zhu, J. Zimsen, S.R.M. Zodpey, S. Zoeckler, L. Zucker, I. Zuhlke, L.J.J. Lim, S.S. Murray, C.J.L. GBD 2017 SDG Collaborators
Abstract: Background: Efforts to establish the 2015 baseline and monitor early implementation of the UN Sustainable Development Goals (SDGs) highlight both great potential for and threats to improving health by 2030. To fully deliver on the SDG aim of “leaving no one behind”, it is increasingly important to examine the health-related SDGs beyond national-level estimates. As part of the Global Burden of Diseases, Injuries, and Risk Factors Study 2017 (GBD 2017), we measured progress on 41 of 52 health-related SDG indicators and estimated the health-related SDG index for 195 countries and territories for the period 1990–2017, projected indicators to 2030, and analysed global attainment. Methods: We measured progress on 41 health-related SDG indicators from 1990 to 2017, an increase of four indicators since GBD 2016 (new indicators were health worker density, sexual violence by non-intimate partners, population census status, and prevalence of physical and sexual violence [reported separately]). We also improved the measurement of several previously reported indicators. We constructed national-level estimates and, for a subset of health-related SDGs, examined indicator-level differences by sex and Socio-demographic Index (SDI) quintile. We also did subnational assessments of performance for selected countries. To construct the health-related SDG index, we transformed the value for each indicator on a scale of 0–100, with 0 as the 2·5th percentile and 100 as the 97·5th percentile of 1000 draws calculated from 1990 to 2030, and took the geometric mean of the scaled indicators by target. To generate projections through 2030, we used a forecasting framework that drew estimates from the broader GBD study and used weighted averages of indicator-specific and country-specific annualised rates of change from 1990 to 2017 to inform future estimates. We assessed attainment of indicators with defined targets in two ways: first, using mean values projected for 2030, and then using the probability of attainment in 2030 calculated from 1000 draws. We also did a global attainment analysis of the feasibility of attaining SDG targets on the basis of past trends. Using 2015 global averages of indicators with defined SDG targets, we calculated the global annualised rates of change required from 2015 to 2030 to meet these targets, and then identified in what percentiles the required global annualised rates of change fell in the distribution of country-level rates of change from 1990 to 2015. We took the mean of these global percentile values across indicators and applied the past rate of change at this mean global percentile to all health-related SDG indicators, irrespective of target definition, to estimate the equivalent 2030 global average value and percentage change from 2015 to 2030 for each indicator. Findings: The global median health-related SDG index in 2017 was 59·4 (IQR 35·4–67·3), ranging from a low of 11·6 (95% uncertainty interval 9·6–14·0) to a high of 84·9 (83·1–86·7). SDG index values in countries assessed at the subnational level varied substantially, particularly in China and India, although scores in Japan and the UK were more homogeneous. Indicators also varied by SDI quintile and sex, with males having worse outcomes than females for non-communicable disease (NCD) mortality, alcohol use, and smoking, among others. Most countries were projected to have a higher health-related SDG index in 2030 than in 2017, while country-level probabilities of attainment by 2030 varied widely by indicator. Under-5 mortality, neonatal mortality, maternal mortality ratio, and malaria indicators had the most countries with at least 95% probability of target attainment. Other indicators, including NCD mortality and suicide mortality, had no countries projected to meet corresponding SDG targets on the basis of projected mean values for 2030 but showed some probability of attainment by 2030. For some indicators, including child malnutrition, several infectious diseases, and most violence measures, the annualised rates of change required to meet SDG targets far exceeded the pace of progress achieved by any country in the recent past. We found that applying the mean global annualised rate of change to indicators without defined targets would equate to about 19% and 22% reductions in global smoking and alcohol consumption, respectively; a 47% decline in adolescent birth rates; and a more than 85% increase in health worker density per 1000 population by 2030. Interpretation: The GBD study offers a unique, robust platform for monitoring the health-related SDGs across demographic and geographic dimensions. Our findings underscore the importance of increased collection and analysis of disaggregated data and highlight where more deliberate design or targeting of interventions could accelerate progress in attaining the SDGs. Current projections show that many health-related SDG indicators, NCDs, NCD-related risks, and violence-related indicators will require a concerted shift away from what might have driven past gains—curative interventions in the case of NCDs—towards multisectoral, prevention-oriented policy action and investments to achieve SDG aims. Notably, several targets, if they are to be met by 2030, demand a pace of progress that no country has achieved in the recent past. The future is fundamentally uncertain, and no model can fully predict what breakthroughs or events might alter the course of the SDGs. What is clear is that our actions—or inaction—today will ultimately dictate how close the world, collectively, can get to leaving no one behind by 2030. Funding: Bill & Melinda Gates Foundation. © 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license
Published: 2018

12. Population and fertility by age and sex for 195 countries and territories, 1950–2017: a systematic analysis for the Global Burden of Disease Study 2017

Author: Murray, C.J.L. Callender, C.S.K.H. Kulikoff, X.R. Srinivasan, V. Abate, D. Abate, K.H. Abay, S.M. Abbasi, N. Abbastabar, H. Abdela, J. Abdelalim, A. Abdel-Rahman, O. Abdi, A. Abdoli, N. Abdollahpour, I. Abdulkader, R.S. Abebe, H.T. Abebe, M. Abebe, Z. Abebo, T.A. Abejie, A.N. Aboyans, V. Abraha, H.N. Abreu, D.M.X. Abrham, A.R. Abu-Raddad, L.J. Abu-Rmeileh, N.M.E. Accrombessi, M.M.K. Acharya, P. Adamu, A.A. Adebayo, O.M. Adedeji, I.A. Adekanmbi, V. Adetokunboh, O.O. Adhena, B.M. Adhikari, T.B. Adib, M.G. Adou, A.K. Adsuar, J.C. Afarideh, M. Afshin, A. Agarwal, G. Agesa, K.M. Aghayan, S.A. Agrawal, S. Ahmadi, A. Ahmadi, M. Ahmed, M.B. Ahmed, S. Aichour, A.N. Aichour, I. Aichour, M.T.E. Akanda, A.S. Akbari, M.E. Akibu, M. Akinyemi, R.O. Akinyemiju, T. Akseer, N. Alahdab, F. Al-Aly, Z. Alam, K. Alebel, A. Aleman, A.V. Alene, K.A. Al-Eyadhy, A. Ali, R. Alijanzadeh, M. Alizadeh-Navaei, R. Aljunid, S.M. Alkerwi, A. Alla, F. Allebeck, P. Almasi, A. Alonso, J. Al-Raddadi, R.M. Alsharif, U. Altirkawi, K. Alvis-Guzman, N. Amare, A.T. Ammar, W. Anber, N.H. Andrei, C.L. Androudi, S. Animut, M.D. Ansari, H. Ansha, M.G. Antonio, C.A.T. Appiah, S.C.Y. Aremu, O. Areri, H.A. Arian, N. Ärnlöv, J. Artaman, A. Aryal, K.K. Asayesh, H. Asfaw, E.T. Asgedom, S.W. Assadi, R. Atey, T.M.M. Atique, S. Atteraya, M.S. Ausloos, M. Avokpaho, E.F.G.A. Awasthi, A. Ayala Quintanilla, B.P. Ayele, Y. Ayer, R. Ayuk, T.B. Azzopardi, P.S. Babalola, T.K. Babazadeh, A. Badali, H. Badawi, A. Bali, A.G. Banach, M. Barker-Collo, S.L. Bärnighausen, T.W. Barrero, L.H. Basaleem, H. Bassat, Q. Basu, A. Baune, B.T. Baynes, H.W. Beghi, E. Behzadifar, M. Behzadifar, M. Bekele, B.B. Belachew, A.B. Belay, A.G. Belay, E. Belay, S.A. Belay, Y.A. Bell, M.L. Bello, A.K. Bennett, D.A. Bensenor, I.M. Bergeron, G. Berhane, A. Berman, A.E. Bernabe, E. Bernstein, R.S. Bertolacci, G.J. Beuran, M. Bhattarai, S. Bhaumik, S. Bhutta, Z.A. Biadgo, B. Bijani, A. Bikbov, B. Bililign, N. Bin Sayeed, M.S. Birlik, S.M. Birungi, C. Biswas, T. Bizuneh, H. Bleyer, A. Basara, B.B. Bosetti, C. Boufous, S. Brady, O.J. Bragazzi, N.L. Brainin, M. Brazinova, A. Breitborde, N.J.K. Brenner, H. Brewer, J.D. Briant, P.S. Britton, G. Burstein, R. Busse, R. Butt, Z.A. Cahuana-Hurtado, L. Campos-Nonato, I.R. Campuzano Rincon, J.C. Cano, J. Car, M. Cárdenas, R. Carrero, J.J. Carvalho, F. Castañeda-Orjuela, C.A. Rivas, J.C. Castro, F. Catalá-López, F. Çavlin, A. Cerin, E. Chalek, J. Chang, H.-Y. Chang, J.-C. Chattopadhyay, A. Chaturvedi, P. Chiang, P.P.-C. Chin, K.L. Chisumpa, V.H. Chitheer, A. Choi, J.-Y.J. Chowdhury, R. Christopher, D.J. Cicuttini, F.M. Ciobanu, L.G. Cirillo, M. Claro, R.M. Collado-Mateo, D. Constantin, M.-M. Conti, S. Cooper, C. Cooper, L.T. Cornaby, L. Cortesi, P.A. Cortinovis, M. Costa, M. Cromwell, E.A. Crowe, C.S. Cukelj, P. Cunningham, M. Daba, A.K. Dachew, B.A. Dandona, L. Dandona, R. Dargan, P.I. Daryani, A. Gupta, R.D. Neves, J.D. Dasa, T.T. Dash, A.P. Davis Weaver, N. Davitoiu, D.V. Davletov, K. De Leo, D. De Neve, J.-W. Degefa, M.G. Degenhardt, L. Degfie, T.T. Deiparine, S. Demoz, G.T. Demtsu, B. Denova-Gutiérrez, E. Deribe, K. Dervenis, N. Des Jarlais, D.C. Dessie, G.A. Dharmaratne, S.D. Dhimal, M. Dicker, D. Ding, E.L. Dinsa, G.D. Djalalinia, S. Do, H.P. Dokova, K. Doku, D.T. Dolan, K.A. Doyle, K.E. Driscoll, T.R. Dubey, M. Dubljanin, E. Duken, E.E. Duraes, A.R. Ebrahimpour, S. Edvardsson, D. El Bcheraoui, C. El-Khatib, Z. Elyazar, I.R. Enayati, A. Endries, A.Y. Ermakov, S.P. Eshrati, B. Eskandarieh, S. Esmaeili, R. Esteghamati, A. Esteghamati, S. Estep, K. Fakhim, H. Farag, T. Faramarzi, M. Fareed, M. SáFarinha, C.S.E. Faro, A. Farvid, M.S. Farzadfar, F. Farzaei, M.H. Fay, K.A. Fazeli, M.S. Feigin, V.L. Feigl, A.B. Feizy, F. Fenny, A.P. Fentahun, N. Fereshtehnejad, S.-M. Fernandes, E. Feyissa, G.T. Filip, I. Finegold, S. Fischer, F. Flor, L.S. Foigt, N.A. Foreman, K.J. Fornari, C. Fürst, T. Fukumoto, T. Fuller, J.E. Fullman, N. Gakidou, E. Gallus, S. Gamkrelidze, A. Ganji, M. Gankpe, F.G. Garcia, G.M. Garcia-Gordillo, M.Á. Gebre, A.K. Gebre, T. Gebregergs, G.B. Gebrehiwot, T.T. Gebremedhin, A.T. Gelano, T.F. Gelaw, Y.A. Geleijnse, J.M. Genova-Maleras, R. Gething, P. Gezae, K.E. Ghadami, M.R. Ghadimi, R. Ghadiri, K. Falavarjani, K.G. Ghasemi-Kasman, M. Ghiasvand, H. Ghimire, M. Ghoshal, A.G. Gill, P.S. Gill, T.K. Giussani, G. Gnedovskaya, E.V. Goli, S. Gomez, R.S. Gómez-Dantés, H. Gona, P.N. Goodridge, A. Gopalani, S.V. Goulart, A.C. Goulart, B.N.G. Grada, A. Grosso, G. Gugnani, H.C.C. Guo, J. Guo, Y. Gupta, P.C. Gupta, R. Gupta, R. Gupta, T. Haagsma, J.A. Hachinski, V. Hafezi-Nejad, N. Hagos, T.B. Hailegiyorgis, T.T. Hailu, G.B. Haj-Mirzaian, A. Haj-Mirzaian, A. Hamadeh, R.R. Hamidi, S. Handal, A.J. Hankey, G.J. Hao, Y. Harb, H.L. Haririan, H. Haro, J.M. Hasan, M. Hassankhani, H. Hassen, H.Y. Havmoeller, R. Hay, S.I. He, Y. Hedayatizadeh-Omran, A. Hegazy, M.I. Heibati, B. Heidari, B. Hendrie, D. Henok, A. Henry, N.J. Herteliu, C. 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Khazaeipour, Z. Khazaie, H. Khoja, A.T. Khosravi, A. Khosravi, M.H. Kibret, G.D. Kidanemariam, Z.T. Kiirithio, D.N. Kilgore, P.E. Kim, D. Kim, J.Y. Kim, Y.-E. Kim, Y.J. Kimokoti, R.W. Kinfu, Y. Kinra, S. Kisa, A. Kivimäki, M. Kochhar, S. Kokubo, Y. Kolola, T. Kopec, J.A. Kosek, M.N. Kosen, S. Koul, P.A. Koyanagi, A. Krishan, K. Krishnaswami, S. Krohn, K.J. Defo, B.K. Bicer, B.K. Kumar, G.A. Kumar, M. Kumar, P. Kumsa, F.A. Kutz, M.J. Lad, S.D. Lafranconi, A. Lal, D.K. Lalloo, R. Lam, H. Lami, F.H. Lang, J.J. Lansky, S. Lansingh, V.C. Laryea, D.O. Lassi, Z.S. Latifi, A. Laxmaiah, A. Lazarus, J.V. Lee, J.B. Lee, P.H. Leigh, J. Leshargie, C.T. Leta, S. Levi, M. Li, S. Li, X. Li, Y. Liang, J. Liang, X. Liben, M.L. Lim, L.-L. Limenih, M.A. Linn, S. Liu, S. Lorkowski, S. Lotufo, P.A. Lozano, R. Lunevicius, R. Mabika, C.M. Macarayan, E.R.K. Mackay, M.T. Madotto, F. Mahmood, T.A.E. Mahotra, N.B. Majdan, M. Majdzadeh, R. Majeed, A. Malekzadeh, R. Malik, M.A. Mamun, A.A. Manamo, W.A. 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Safari-Faramani, R. Safdarian, M. Safi, S. Safiri, S. Sagar, R. Sahebkar, A. Sahraian, M.A. Sajadi, H.S. Salahshoor, M. Salam, N. Salama, J.S. Salamati, P. Saldanha, R.D.F. Saleem, Z. Salimi, Y. Salimzadeh, H. Salomon, J.A. Salvi, S.S. Salz, I. Sambala, E.Z. Samy, A.M. Sanabria, J. Sanchez-Niño, M.D. Santos, I.S. Santric Milicevic, M.M. Sao Jose, B.P. Sardana, M. Sarker, A.R. Sarmiento-Suárez, R. Saroshe, S. Sarrafzadegan, N. Sartorius, B. Sarvi, S. Sathian, B. Satpathy, M. Sawant, A.R. Sawhney, M. Saxena, S. Schaeffner, E. Schelonka, K. Schneider, I.J.C. Schwebel, D.C. Schwendicke, F. Seedat, S. Sekerija, M. Sepanlou, S.G. Serván-Mori, E. Shabaninejad, H. Shackelford, K.A. Shafieesabet, A. Shaheen, A.A. Shaikh, M.A. Shakir, R.A. Shams-Beyranvand, M. Shamsi, M. Shamsizadeh, M. Sharafi, H. Sharafi, K. Sharif, M. Sharif-Alhoseini, M. Sharma, J. Sharma, R. She, J. Sheikh, A. Shi, P. Shibuya, K. Shigematsu, M. Shiri, R. Shirkoohi, R. Shiue, I. Shokraneh, F. Shukla, S.R. Si, S. Siabani, S. Sibai, A.M. Siddiqi, T.J. Sigfusdottir, I.D. Sigurvinsdottir, R. Silpakit, N. Silva, D.A.S. Silva, J.P. Silveira, D.G.A. Singam, N.S.V. Singh, J.A. Singh, N.P. Singh, V. Sinha, D.N. Sliwa, K. Soares Filho, A.M. Sobaih, B.H. Sobhani, S. Soofi, M. Soriano, J.B. Soyiri, I.N. Sreeramareddy, C.T. Starodubov, V.I. Steiner, C. Stewart, L.G. Stokes, M.A. Strong, M. Subart, M.L. Sufiyan, M.B. Sulo, G. Sunguya, B.F. Sur, P.J. Sutradhar, I. Sykes, B.L. Sylaja, P.N. Sylte, D.O. Szoeke, C.E.I. Tabarés-Seisdedos, R. Tabb, K.M. Tadakamadla, S.K. Tandon, N. Tassew, A.A. Tassew, S.G. Taveira, N. Tawye, N.Y. Tehrani-Banihashemi, A. Tekalign, T.G. Tekle, M.G. Temsah, M.-H. Terkawi, A.S. Teshale, M.Y. Tessema, B. Teweldemedhin, M. Thakur, J.S. Thankappan, K.R. Thirunavukkarasu, S. Thomas, N. Thomson, A.J. Tilahun, B. To, Q.G. Tonelli, M. Topor-Madry, R. Torre, A.E. Tortajada-Girbés, M. Tovani-Palone, M.R. Toyoshima, H. Tran, B.X. Tran, K.B. Tripathy, S.P. Truelsen, T.C. Truong, N.T. Tsadik, A.G. Tsegay, A. Tsilimparis, N. Car, L.T. Ukwaja, K.N. Ullah, I. Usman, M.S. Uthman, O.A. Uzun, S.B. Vaduganathan, M. Vaezi, A. Vaidya, G. Valdez, P.R. Varavikova, E. Varughese, S. Vasankari, T.J. Vasconcelos, A.M.N. Venketasubramanian, N. Villafaina, S. Violante, F.S. Vladimirov, S.K. Vlassov, V. Vollset, S.E. Vos, T. Vosoughi, K. Vujcic, I.S. Wagnew, F.S. Waheed, Y. Walson, J.L. Wang, Y. Wang, Y.-P. Weiderpass, E. Weintraub, R.G. Weldegwergs, K.G. Werdecker, A. Westerman, R. Whiteford, H. Widecka, J. Widecka, K. Wijeratne, T. Winkler, A.S. Wiysonge, C.S. Wolfe, C.D.A. Wu, S. Wyper, G.M.A. Xu, G. Yamada, T. Yano, Y. Yaseri, M. Yasin, Y.J. Ye, P. Yentür, G.K. Yeshaneh, A. Yimer, E.M. Yip, P. Yisma, E. Yonemoto, N. Yoon, S.-J. Yotebieng, M. Younis, M.Z. Yousefifard, M. Yu, C. Zadnik, V. Zaidi, Z. Zaman, S.B. Zamani, M. Zare, Z. Zeleke, M.M. Zenebe, Z.M. Zerfu, T.A. Zhang, X. Zhao, X.-J. Zhou, M. Zhu, J. Zimsen, S.R.M. Zodpey, S. Zoeckler, L. Lopez, A.D. Lim, S.S. GBD 2017 Population Fertility Collaborators
Abstract: Background: Population estimates underpin demographic and epidemiological research and are used to track progress on numerous international indicators of health and development. To date, internationally available estimates of population and fertility, although useful, have not been produced with transparent and replicable methods and do not use standardised estimates of mortality. We present single-calendar year and single-year of age estimates of fertility and population by sex with standardised and replicable methods. Methods: We estimated population in 195 locations by single year of age and single calendar year from 1950 to 2017 with standardised and replicable methods. We based the estimates on the demographic balancing equation, with inputs of fertility, mortality, population, and migration data. Fertility data came from 7817 location-years of vital registration data, 429 surveys reporting complete birth histories, and 977 surveys and censuses reporting summary birth histories. We estimated age-specific fertility rates (ASFRs; the annual number of livebirths to women of a specified age group per 1000 women in that age group) by use of spatiotemporal Gaussian process regression and used the ASFRs to estimate total fertility rates (TFRs; the average number of children a woman would bear if she survived through the end of the reproductive age span [age 10–54 years] and experienced at each age a particular set of ASFRs observed in the year of interest). Because of sparse data, fertility at ages 10–14 years and 50–54 years was estimated from data on fertility in women aged 15–19 years and 45–49 years, through use of linear regression. Age-specific mortality data came from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 estimates. Data on population came from 1257 censuses and 761 population registry location-years and were adjusted for underenumeration and age misreporting with standard demographic methods. Migration was estimated with the GBD Bayesian demographic balancing model, after incorporating information about refugee migration into the model prior. Final population estimates used the cohort-component method of population projection, with inputs of fertility, mortality, and migration data. Population uncertainty was estimated by use of out-of-sample predictive validity testing. With these data, we estimated the trends in population by age and sex and in fertility by age between 1950 and 2017 in 195 countries and territories. Findings: From 1950 to 2017, TFRs decreased by 49·4% (95% uncertainty interval [UI] 46·4–52·0). The TFR decreased from 4·7 livebirths (4·5–4·9) to 2·4 livebirths (2·2–2·5), and the ASFR of mothers aged 10–19 years decreased from 37 livebirths (34–40) to 22 livebirths (19–24) per 1000 women. Despite reductions in the TFR, the global population has been increasing by an average of 83·8 million people per year since 1985. The global population increased by 197·2% (193·3–200·8) since 1950, from 2·6 billion (2·5–2·6) to 7·6 billion (7·4–7·9) people in 2017; much of this increase was in the proportion of the global population in south Asia and sub-Saharan Africa. The global annual rate of population growth increased between 1950 and 1964, when it peaked at 2·0%; this rate then remained nearly constant until 1970 and then decreased to 1·1% in 2017. Population growth rates in the southeast Asia, east Asia, and Oceania GBD super-region decreased from 2·5% in 1963 to 0·7% in 2017, whereas in sub-Saharan Africa, population growth rates were almost at the highest reported levels ever in 2017, when they were at 2·7%. The global average age increased from 26·6 years in 1950 to 32·1 years in 2017, and the proportion of the population that is of working age (age 15–64 years) increased from 59·9% to 65·3%. At the national level, the TFR decreased in all countries and territories between 1950 and 2017; in 2017, TFRs ranged from a low of 1·0 livebirths (95% UI 0·9–1·2) in Cyprus to a high of 7·1 livebirths (6·8–7·4) in Niger. The TFR under age 25 years (TFU25; number of livebirths expected by age 25 years for a hypothetical woman who survived the age group and was exposed to current ASFRs) in 2017 ranged from 0·08 livebirths (0·07–0·09) in South Korea to 2·4 livebirths (2·2–2·6) in Niger, and the TFR over age 30 years (TFO30; number of livebirths expected for a hypothetical woman ageing from 30 to 54 years who survived the age group and was exposed to current ASFRs) ranged from a low of 0·3 livebirths (0·3–0·4) in Puerto Rico to a high of 3·1 livebirths (3·0–3·2) in Niger. TFO30 was higher than TFU25 in 145 countries and territories in 2017. 33 countries had a negative population growth rate from 2010 to 2017, most of which were located in central, eastern, and western Europe, whereas population growth rates of more than 2·0% were seen in 33 of 46 countries in sub-Saharan Africa. In 2017, less than 65% of the national population was of working age in 12 of 34 high-income countries, and less than 50% of the national population was of working age in Mali, Chad, and Niger. Interpretation: Population trends create demographic dividends and headwinds (ie, economic benefits and detriments) that affect national economies and determine national planning needs. Although TFRs are decreasing, the global population continues to grow as mortality declines, with diverse patterns at the national level and across age groups. To our knowledge, this is the first study to provide transparent and replicable estimates of population and fertility, which can be used to inform decision making and to monitor progress. Funding: Bill & Melinda Gates Foundation. © 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license
Published: 2018

13. Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2017: A systematic analysis for the Global Burden of Disease Study 2017

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Animut, M.D. Anjomshoa, M. Ansha, M.G. Antonio, C.A.T. Anwari, P. Arabloo, J. Aremu, O. Ärnlöv, J. Arora, A. Arora, M. Artaman, A. Aryal, K.K. Asayesh, H. Ataro, Z. Ausloos, M. Avila-Burgos, L. Avokpaho, E.F.G.A. Awasthi, A. Ayala Quintanilla, B.P. Ayer, R. Azzopardi, P.S. Babazadeh, A. Badali, H. Balakrishnan, K. Bali, A.G. Banach, M. Banoub, J.A.M. Barac, A. Barboza, M.A. Barker-Collo, S.L. Bärnighausen, T.W. Barquera, S. Barrero, L.H. Bazargan-Hejazi, S. Bedi, N. Beghi, E. Behzadifar, M. Behzadifar, M. Bekele, B.B. Bekru, E.T. Belachew, A.B. Belay, Y.A. Bell, M.L. Bello, A.K. Bennett, D.A. Bensenor, I.M. Berhane, A. Bernabe, E. Bernstein, R.S. Beuran, M. Beyranvand, T. Bhala, N. Bhatt, S. Bhaumik, S. Bhutta, Z.A. Biadgo, B. Biehl, M.H. Bijani, A. Bikbov, B. Bilano, V. Bililign, N. Bin Sayeed, M.S. Bisanzio, D. Bjorge, T. Bleyer, A. Bobasa, E.M. Bou-Orm, I.R. Boufous, S. Bourne, R. Brady, O.J. Brant, L.C. Brayne, C. Brazinova, A. Breitborde, N.J.K. Brenner, H. Briant, P.S. 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Driscoll, T.R. Dubey, M. Dubljanin, E. Duken, E.E. Duncan, B.B. Duraes, A.R. Ebrahimi, H. Ebrahimpour, S. Echko, M.M. Edessa, D. Edvardsson, D. Effiong, A. Eggen, A.E. Ehrlich, J.R. El Bcheraoui, C. El-Khatib, Z. Elyazar, I.R.F. Enayati, A. Endalifer, M.L. Endries, A.Y. Er, B. Erskine, H.E. Eskandarieh, S. Esteghamati, A. Esteghamati, S. Fakhim, H. Faramarzi, M. Fareed, M. Farhadi, F. Farid, T.A. Sá Farinha, C.S.E. Farioli, A. Faro, A. Farzadfar, F. Fazaeli, A.A. Feigin, V.L. Fentahun, N. Fereshtehnejad, S.-M. Fernandes, E. Fernandes, J.C. Ferrari, A.J. Ferreira, M.L. Filip, I. Fischer, F. Fitzmaurice, C. Foigt, N.A. Foreman, K.J. Frank, T.D. Fukumoto, T. Fullman, N. Fürst, T. Furtado, J.M. Gakidou, E. Gall, S. Gallus, S. Ganji, M. Garcia-Basteiro, A.L. Gardner, W.M. Gebre, A.K. Gebremedhin, A.T. Gebremichael, T.G. Gelano, T.F. Geleijnse, J.M. Genova-Maleras, R. Geramo, Y.C.D. Gething, P.W. Gezae, K.E. Ghadami, M.R. Ghadiri, K. Ghasemi-Kasman, M. Ghimire, M. Ghoshal, A.G. Gill, P.S. Gill, T.K. Ginawi, I.A. Giussani, G. Gnedovskaya, E.V. Goldberg, E.M. Goli, S. Gómez-Dantés, H. Gona, P.N. Gopalani, S.V. Gorman, T.M. Goulart, A.C. Goulart, B.N.G. Grada, A. Grosso, G. Gugnani, H.C. Guillemin, F. Guo, Y. Gupta, P.C. Gupta, R. Gupta, R. Gupta, T. Gutiérrez, R.A. Gyawali, B. Haagsma, J.A. Hachinski, V. Hafezi-Nejad, N. Bidgoli, H.H. Hagos, T.B. Hailegiyorgis, T.T. Haj-Mirzaian, A. Haj-Mirzaian, A. Hamadeh, R.R. Hamidi, S. Handal, A.J. Hankey, G.J. Hao, Y. Harb, H.L. Harikrishnan, S. Haririan, H. Haro, J.M. Hassankhani, H. Hassen, H.Y. Havmoeller, R. Hay, R.J. Hay, S.I. Hedayatizadeh-Omran, A. Heibati, B. Hendrie, D. Henok, A. Heredia-Pi, I. Herteliu, C. Heydarpour, F. Heydarpour, P. Hibstu, D.T. Hoek, H.W. Hoffman, H.J. Hole, M.K. Rad, E.H. Hoogar, P. Hosgood, H.D. Hosseini, S.M. Hosseinzadeh, M. Hostiuc, M. Hostiuc, S. Hotez, P.J. Hoy, D.G. Hsairi, M. Htet, A.S. Huang, J.J. Iburg, K.M. Ikeda, C.T. Ilesanmi, O.S. Irvani, S.S.N. Irvine, C.M.S. Islam, S.M.S. Islami, F. 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Maulik, P.K. Mazidi, M. McAlinden, C. McGrath, J.J. McKee, M. McMahon, B.J. Mehata, S. Mehrotra, R. Mehta, K.M. Mehta, V. Mejia-Rodriguez, F. Mekonen, T. Melese, A. Melku, M. Memiah, P.T.N. Memish, Z.A. Mendoza, W. Mengistu, G. Mensah, G.A. Mereta, S.T. Meretoja, A. Meretoja, T.J. Mestrovic, T. Miazgowski, B. Miazgowski, T. Millear, A.I. Miller, T.R. Mini, G.K. Mirarefin, M. Mirica, A. Mirrakhimov, E.M. Misganaw, A.T. Mitchell, P.B. Mitiku, H. Moazen, B. Mohajer, B. Mohammad, K.A. Mohammadi, M. Mohammadifard, N. Mohammadnia-Afrouzi, M. Mohammed, M.A. Mohammed, S. Mohebi, F. Mokdad, A.H. Molokhia, M. Monasta, L. Montanez, J.C. Moosazadeh, M. Moradi, G. Moradi, M. Moradi-Lakeh, M. Moradinazar, M. Moraga, P. Morawska, L. Velásquez, I.M. Morgado-Da-Costa, J. Morrison, S.D. Moschos, M.M. Mousavi, S.M. Mruts, K.B. Muche, A.A. Muchie, K.F. Mueller, U.O. Muhammed, O.S. Mukhopadhyay, S. Muller, K. Mumford, J.E. Murthy, G.V.S. Musa, K.I. Mustafa, G. Nabhan, A.F. Nagata, C. Nagel, G. Naghavi, M. Naheed, A. Nahvijou, A. Naik, G. Najafi, F. Nam, H.S. Nangia, V. Nansseu, J.R. Neamati, N. Negoi, I. Negoi, R.I. Neupane, S. Newton, C.R.J. Ngunjiri, J.W. Nguyen, A.Q. Nguyen, G. Nguyen, H.T. Nguyen, H.L.T. Nguyen, H.T. Nguyen, L.H. Nguyen, M. Nguyen, N.B. Nguyen, S.H. Nichols, E. Ningrum, D.N.A. Nixon, M.R. Nomura, S. Noroozi, M. Norrving, B. Noubiap, J.J. Nouri, H.R. Shiadeh, M.N. Nowroozi, M.R. Nsoesie, E.O. Nyasulu, P.S. Odell, C.M. Ofori-Asenso, R. Ogbo, F.A. Oh, I.-H. Oladimeji, O. Olagunju, A.T. Olagunju, T.O. Olivares, P.R. Olsen, H.E. Olusanya, B.O. Olusanya, J.O. Ong, K.L. Ong, S.K. Oren, E. Ortiz, A. Ota, E. Otstavnov, S.S. Overland, S. Owolabi, M.O. Mahesh, P.A. Pacella, R. Pakhare, A.P. Pakpour, A.H. Pana, A. Panda-Jonas, S. Park, E.-K. Park, J. Parry, C.D.H. Parsian, H. Pasdar, Y. Patel, S. Patil, S.T. Patle, A. Patton, G.C. Paturi, V.R. Paudel, D. Paulson, K.R. Pearce, N. Pereira, A. Pereira, D.M. Perico, N. Pesudovs, K. Petzold, M. Pham, H.Q. Phillips, M.R. Pigott, D.M. Pillay, J.D. Piradov, M.A. Pirsaheb, M. Pishgar, F. Plana-Ripoll, O. Polinder, S. Popova, S. Postma, M.J. Pourshams, A. Poustchi, H. Prabhakaran, D. Prakash, S. Prakash, V. Prasad, N. Purcell, C.A. Qorbani, M. Quistberg, D.A. Radfar, A. Rafay, A. Rafiei, A. Rahim, F. Rahimi, K. Rahimi, Z. Rahimi-Movaghar, A. Rahimi-Movaghar, V. Rahman, M. Ur Rahman, M.H. Rahman, M.A. Rahman, S.U. Rai, R.K. Rajati, F. Ranjan, P. Rao, P.C. Rasella, D. Rawaf, D.L. Rawaf, S. Reddy, K.S. Reiner, R.C. Reitsma, M.B. Remuzzi, G. Renzaho, A.M.N. Resnikoff, S. Rezaei, S. Rezai, M.S. Ribeiro, A.L.P. Roberts, N.L.S. Robinson, S.R. Roever, L. Ronfani, L. Roshandel, G. Rostami, A. Roth, G.A. Rothenbacher, D. Rubagotti, E. Sachdev, P.S. Sadat, N. Sadeghi, E. Saeedi Moghaddam, S. Safari, H. Safari, Y. Safari-Faramani, R. Safdarian, M. Safi, S. Safiri, S. Sagar, R. Sahebkar, A. Sahraian, M.A. Sajadi, H.S. Salam, N. Salama, J.S. Salamati, P. Saleem, Z. Salimi, Y. Salimzadeh, H. Salomon, J.A. Salvi, S.S. Salz, I. Samy, A.M. Sanabria, J. Sanchez-Nino, M.D. Santomauro, D.F. Santos, I.S. Santos, J.V. Santric Milicevic, M.M. Sao Jose, B.P. Sardana, M. Sarker, A.R. Sarmiento-Suárez, R. Sarrafzadegan, N. Sartorius, B. Sarvi, S. Sathian, B. Satpathy, M. Sawant, A.R. Sawhney, M. Saxena, S. Schaeffner, E. Schmidt, M.I. Schneider, I.J.C. Schutte, A.E. Schwebel, D.C. Schwendicke, F. Scott, J.G. Sekerija, M. Sepanlou, S.G. Serván-Mori, E. Seyedmousavi, S. Shabaninejad, H. Shafieesabet, A. Shahbazi, M. Shaheen, A.A. Shaikh, M.A. Shams-Beyranvand, M. Shamsi, M. Sharafi, H. Sharafi, K. Sharif, M. Sharif-Alhoseini, M. Sharma, J. Sharma, R. She, J. Sheikh, A. Shi, P. Shibuya, K. Shiferaw, M.S. Shigematsu, M. Shiri, R. Shirkoohi, R. Shiue, I. Shokoohinia, Y. Shokraneh, F. Shoman, H. Shrime, M.G. Si, S. Siabani, S. Sibai, A.M. Siddiqi, T.J. Sigfusdottir, I.D. Sigurvinsdottir, R. Silva, D.A.S. Silva, J.P. Silveira, D.G.A. Singam, N.S.V. Singh, J.A. Singh, N.P. Singh, V. Sinha, D.N. Skiadaresi, E. Skirbekk, V. Sliwa, K. Smith, D.L. Smith, M. Filho, A.M.S. Sobaih, B.H. Sobhani, S. Soofi, M. Sorensen, R.J.D. Soyiri, I.N. Sposato, L.A. Sreeramareddy, C.T. Srinivasan, V. Stanaway, J.D. Starodubov, V.I. Stein, D.J. Steiner, C. Steiner, T.J. Stokes, M.A. Stovner, L.J. Subart, M.L. Sudaryanto, A. Sufiyan, M.B. Sulo, G. Sunguya, B.F. Sur, P.J. Sykes, B.L. Sylaja, P.N. Sylte, D.O. Szoeke, C.E.I. Tabarés-Seisdedos, R. Tabuchi, T. Tadakamadla, S.K. Tandon, N. Tassew, S.G. Tavakkoli, M. Taveira, N. Taylor, H.R. Tehrani-Banihashemi, A. Tekalign, T.G. Tekelemedhin, S.W. Tekle, M.G. Temsah, M.-H. Temsah, O. Terkawi, A.S. Tessema, B. Teweldemedhin, M. Thankappan, K.R. Theis, A. Thirunavukkarasu, S. Thomas, N. Tilahun, B. To, Q.G. Tonelli, M. Topor-Madry, R. Torre, A.E. Tortajada-Girbés, M. Touvier, M. Tovani-Palone, M.R. Towbin, J.A. Tran, B.X. Tran, K.B. Troeger, C.E. Tsadik, A.G. Tsoi, D. Tudor Car, L. Tyrovolas, S. Ukwaja, K.N. Ullah, I. Undurraga, E.A. Updike, R.L. Usman, M.S. Uthman, O.A. Vaduganathan, M. Vaezi, A. Valdez, P.R. Varavikova, E. Varughese, S. Vasankari, T.J. Venketasubramanian, N. Villafaina, S. Violante, F.S. Vladimirov, S.K. Vlassov, V. Vollset, S.E. Vos, T. Vosoughi, K. Vujcic, I.S. Wagnew, F.S. Waheed, Y. Wang, Y. Wang, Y.-P. Weiderpass, E. Weintraub, R.G. Weiss, D.J. Weldegebreal, F. Weldegwergs, K.G. Werdecker, A. West, T.E. Westerman, R. Whiteford, H.A. Widecka, J. Wijeratne, T. Williams, H.C. Wilner, L.B. Wilson, S. Winkler, A.S. Wiyeh, A.B. Wiysonge, C.S. Wolfe, C.D.A. Woolf, A.D. Wyper, G.M.A. Xavier, D. Xu, G. Yadgir, S. Yahyazadeh Jabbari, S.H. Yamada, T. Yan, L.L. Yano, Y. Yaseri, M. Yasin, Y.J. Yeshaneh, A. Yimer, E.M. Yip, P. Yisma, E. Yonemoto, N. Yoon, S.-J. Yotebieng, M. Younis, M.Z. Yousefifard, M. Yu, C. Zadnik, V. Zaidi, Z. Zaman, S.B. Zamani, M. Zandian, H. Zar, H.J. Zenebe, Z.M. Zipkin, B. Zhou, M. Zodpey, S. Zucker, I. Zuhlke, L.J. Murray, C.J.L. GBD 2017 DALYs HALE Collaborators
Abstract: Background: How long one lives, how many years of life are spent in good and poor health, and how the population's state of health and leading causes of disability change over time all have implications for policy, planning, and provision of services. We comparatively assessed the patterns and trends of healthy life expectancy (HALE), which quantifies the number of years of life expected to be lived in good health, and the complementary measure of disability-adjusted lifeyears (DALYs), a composite measure of disease burden capturing both premature mortality and prevalence and severityof ill health, for 359 diseases and injuries for 195 countries and territories over the past 28 years. Methods We used data for age-speci?c mortality rates, years of life lost (YLLs) due to premature mortality, and years lived with disability (YLDs) from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 to calculate HALE and DALYs from 1990 to 2017. We calculated HALE using age-specific mortality rates and YLDs per capita for each location, age, sex, and year. We calculated DALYs for 359 causes as the sum of YLLs and YLDs. We assessed how observed HALE and DALYs differed by country and sex from expected trends based on Sociodemographic Index (SDI). We also analysed HALE by decomposing years of life gained into years spent in good health and in poor health, between 1990 and 2017, and extra years lived by females compared with males. Findings Globally, from 1990 to 2017, life expectancy at birth increased by 7·4 years (95% uncertainty interval 7·1-7·8), from 65·6 years (65·3-65·8) in 1990 to 73·0 years (72·7-73·3) in 2017. The increase in years of life varied from 5·1 years (5·0-5·3) in high SDI countries to 12·0 years (11·3-12·8) in low SDI countries. Of the additional years of life expected at birth, 26·3% (20·1-33·1) were expected to be spent in poor health in high SDI countries compared with 11·7% (8·8-15·1) in low-middle SDI countries. HALE at birth increased by 6·3 years (5·9-6·7), from 57·0 years (54·6-59·1) in 1990 to 63·3 years (60·5-65·7) in 2017. The increase varied from 3·8 years (3·4-4·1) in high SDI countries to 10·5 years (9·8-11·2) in low SDI countries. Even larger variations in HALE than these were observed between countries, ranging from 1·0 year (0·4-1·7) in Saint Vincent and the Grenadines (62·4 years [59·9-64·7] in 1990 to 63·5 years [60·9-65·8] in 2017) to 23·7 years (21·9-25·6) in Eritrea (30·7 years [28·9-32·2] in 1990 to 54·4 years [51·5-57·1] in 2017). In most countries, the increase in HALE was smaller than the increase in overall life expectancy, indicating more years lived in poor health. In 180 of 195 countries and territories, females were expected to live longer than males in 2017, with extra years lived varying from 1·4 years (0·6-2·3) in Algeria to 11·9 years (10·9-12·9) in Ukraine. Of the extra years gained, the proportion spent in poor health varied largely across countries, with less than 20% of additional years spent in poor health in Bosnia and Herzegovina, Burundi, and Slovakia, whereas in Bahrain all the extra years were spent in poor health. In 2017, the highest estimate of HALE at birth was in Singapore for both females (75·8 years [72·4-78·7]) and males (72·6 years [69·8-75·0]) and the lowest estimates were in Central African Republic (47·0 years [43·7-50·2] for females and 42·8 years [40·1-45·6] for males). Globally, in 2017, the ?ve leading causes of DALYs were neonatal disorders, ischaemic heart disease, stroke, lower respiratory infections, and chronic obstructive pulmonary disease. Between 1990 and 2017, age-standardised DALY rates decreased by 41·3% (38·8-43·5) for communicable diseases and by 49·8% (47·9-51·6) for neonatal disorders. For non-communicable diseases, global DALYs increased by 40·1% (36·8-43·0), although age-standardised DALY rates decreased by 18·1% (16·0-20·2). Interpretation With increasing life expectancy in most countries, the question of whether the additional years of life gained are spent in good health or poor health has been increasingly relevant because of the potential policy implications, such as health-care provisions and extending retirement ages. In some locations, a large proportion of those additional years are spent in poor health. Large inequalities in HALE and disease burden exist across countries in different SDI quintiles and between sexes. The burden of disabling conditions has serious implications for health system planning and health-related expenditures. Despite the progress made in reducing the burden of communicable diseases and neonatal disorders in low SDI countries, the speed of this progress could be increased by scaling up proven interventions. The global trends among non-communicable diseases indicate that more effort is needed to maximise HALE, such as risk prevention and attention to upstream determinants of health. Copyright © 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.
Published: 2018

14. Global, regional, and national incidence, prevalence, and years lived with disability for 354 Diseases and Injuries for 195 countries and territories, 1990-2017: A systematic analysis for the Global Burden of Disease Study 2017

Author: James, S.L. Abate, D. Abate, K.H. Abay, S.M. Abbafati, C. Abbasi, N. Abbastabar, H. Abd-Allah, F. Abdela, J. Abdelalim, A. Abdollahpour, I. Abdulkader, R.S. Abebe, Z. Abera, S.F. Abil, O.Z. Abraha, H.N. Abu-Raddad, L.J. Abu-Rmeileh, N.M.E. Accrombessi, M.M.K. Acharya, D. Acharya, P. Ackerman, I.N. Adamu, A.A. Adebayo, O.M. Adekanmbi, V. Adetokunboh, O.O. Adib, M.G. Adsuar, J.C. Afanvi, K.A. Afarideh, M. Afshin, A. Agarwal, G. Agesa, K.M. Aggarwal, R. Aghayan, S.A. Agrawal, S. Ahmadi, A. Ahmadi, M. Ahmadieh, H. Ahmed, M.B. Aichour, A.N. Aichour, I. Aichour, M.T.E. Akinyemiju, T. Akseer, N. Al-Aly, Z. Al-Eyadhy, A. Al-Mekhlafi, H.M. Al-Raddadi, R.M. Alahdab, F. Alam, K. Alam, T. Alashi, A. Alavian, S.M. Alene, K.A. Alijanzadeh, M. Alizadeh-Navaei, R. Aljunid, S.M. Alkerwi, A. Alla, F. Allebeck, P. Alouani, M.M.L. Altirkawi, K. Alvis-Guzman, N. Amare, A.T. Aminde, L.N. Ammar, W. Amoako, Y.A. Anber, N.H. Andrei, C.L. Androudi, S. Animut, M.D. Anjomshoa, M. Ansha, M.G. Antonio, C.A.T. Anwari, P. Arabloo, J. Arauz, A. Aremu, O. Ariani, F. Armoon, B. Ärnlöv, J. Arora, A. Artaman, A. Aryal, K.K. Asayesh, H. Asghar, R.J. Ataro, Z. Atre, S.R. Ausloos, M. Avila-Burgos, L. Avokpaho, E.F.G.A. Awasthi, A. Ayala Quintanilla, B.P. Ayer, R. Azzopardi, P.S. Babazadeh, A. Badali, H. Badawi, A. Bali, A.G. Ballesteros, K.E. Ballew, S.H. Banach, M. Banoub, J.A.M. Banstola, A. Barac, A. Barboza, M.A. Barker-Collo, S.L. Bärnighausen, T.W. Barrero, L.H. Baune, B.T. Bazargan-Hejazi, S. Bedi, N. Beghi, E. Behzadifar, M. Behzadifar, M. Béjot, Y. Belachew, A.B. Belay, Y.A. Bell, M.L. Bello, A.K. Bensenor, I.M. Bernabe, E. Bernstein, R.S. Beuran, M. Beyranvand, T. Bhala, N. Bhattarai, S. Bhaumik, S. Bhutta, Z.A. Biadgo, B. Bijani, A. Bikbov, B. Bilano, V. Bililign, N. Bin Sayeed, M.S. Bisanzio, D. Blacker, B.F. Blyth, F.M. Bou-Orm, I.R. Boufous, S. Bourne, R. Brady, O.J. Brainin, M. Brant, L.C. Brazinova, A. Breitborde, N.J.K. Brenner, H. Briant, P.S. Briggs, A.M. 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Dinberu, M.T. Dirac, M.A. Djalalinia, S. Doan, L. Dokova, K. Doku, D.T. Dorsey, E.R. Doyle, K.E. Driscoll, T.R. Dubey, M. Dubljanin, E. Duken, E.E. Duncan, B.B. Duraes, A.R. Ebrahimi, H. Ebrahimpour, S. Echko, M.M. Edvardsson, D. Effiong, A. Ehrlich, J.R. El Bcheraoui, C. El Sayed Zaki, M. El-Khatib, Z. Elkout, H. Elyazar, I.R.F. Enayati, A. Endries, A.Y. Er, B. Erskine, H.E. Eshrati, B. Eskandarieh, S. Esteghamati, A. Esteghamati, S. Fakhim, H. Fallah Omrani, V. Faramarzi, M. Fareed, M. Farhadi, F. Farid, T.A. Farinha, C.S.E. Farioli, A. Faro, A. Farvid, M.S. Farzadfar, F. Feigin, V.L. Fentahun, N. Fereshtehnejad, S.-M. Fernandes, E. Fernandes, J.C. Ferrari, A.J. Feyissa, G.T. Filip, I. Fischer, F. Fitzmaurice, C. Foigt, N.A. Foreman, K.J. Fox, J. Frank, T.D. Fukumoto, T. Fullman, N. Fürst, T. Furtado, J.M. Futran, N.D. Gall, S. Ganji, M. Gankpe, F.G. Garcia-Basteiro, A.L. Gardner, W.M. Gebre, A.K. Gebremedhin, A.T. Gebremichael, T.G. Gelano, T.F. Geleijnse, J.M. Genova-Maleras, R. 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Hoy, D.G. Hsairi, M. Htet, A.S. Hu, G. Huang, J.J. Huynh, C.K. Iburg, K.M. Ikeda, C.T. Ileanu, B. Ilesanmi, O.S. Iqbal, U. Irvani, S.S.N. Irvine, C.M.S. Mohammed, S. Islam, S. Islami, F. Jacobsen, K.H. Jahangiry, L. Jahanmehr, N. Jain, S.K. Jakovljevic, M. Javanbakht, M. Jayatilleke, A.U. Jeemon, P. Jha, R.P. Jha, V. Ji, J.S. Johnson, C.O. Jonas, J.B. Jozwiak, J.J. Jungari, S.B. Jürisson, M. Kabir, Z. Kadel, R. Kahsay, A. Kalani, R. Kanchan, T. Karami, M. Karami Matin, B. Karch, A. Karema, C. Karimi, N. Karimi, S.M. Kasaeian, A. Kassa, D.H. Kassa, G.M. Kassa, T.D. Kassebaum, N.J. Katikireddi, S.V. Kawakami, N. Kazemi Karyani, A. Keighobadi, M.M. Keiyoro, P.N. Kemmer, L. Kemp, G.R. Kengne, A.P. Keren, A. Khader, Y.S. Khafaei, B. Khafaie, M.A. Khajavi, A. Khalil, I.A. Khan, E.A. Khan, M.S. Khan, M.A. Khang, Y.-H. Khazaei, M. Khoja, A.T. Khosravi, A. Khosravi, M.H. Kiadaliri, A.A. Kiirithio, D.N. Kim, C.-I. Kim, D. Kim, P. Kim, Y.-E. Kim, Y.J. Kimokoti, R.W. Kinfu, Y. Kisa, A. Kissimova-Skarbek, K. Kivimäki, M. Knudsen, A.K.S. Kocarnik, J.M. Kochhar, S. Kokubo, Y. Kolola, T. Kopec, J.A. Kosen, S. Kotsakis, G.A. Koul, P.A. Koyanagi, A. Kravchenko, M.A. Krishan, K. Krohn, K.J. Kuate Defo, B. Kucuk Bicer, B. Kumar, G.A. Kumar, M. Kyu, H.H. Lad, D.P. Lad, S.D. Lafranconi, A. Lalloo, R. Lallukka, T. Lami, F.H. Lansingh, V.C. Latifi, A. Lau, K.M.-M. Lazarus, J.V. Leasher, J.L. Ledesma, J.R. Lee, P.H. Leigh, J. Leung, J. Levi, M. Lewycka, S. Li, S. Li, Y. Liao, Y. Liben, M.L. Lim, L.-L. Lim, S.S. Liu, S. Lodha, R. Looker, K.J. Lopez, A.D. Lorkowski, S. Lotufo, P.A. Low, N. Lozano, R. Lucas, T.C.D. Lucchesi, L.R. Lunevicius, R. Lyons, R.A. Ma, S. Macarayan, E.R.K. Mackay, M.T. Madotto, F. Magdy Abd El Razek, H. Magdy Abd El Razek, M. Maghavani, D.P. Mahotra, N.B. Mai, H.T. Majdan, M. Majdzadeh, R. Majeed, A. Malekzadeh, R. Malta, D.C. Mamun, A.A. Manda, A.-L. Manguerra, H. Manhertz, T. Mansournia, M.A. Mantovani, L.G. Mapoma, C.C. Maravilla, J.C. Marcenes, W. Marks, A. Martins-Melo, F.R. Martopullo, I. März, W. Marzan, M.B. Mashamba-Thompson, T.P. Massenburg, B.B. Mathur, M.R. Matsushita, K. Maulik, P.K. Mazidi, M. McAlinden, C. McGrath, J.J. McKee, M. Mehndiratta, M.M. Mehrotra, R. Mehta, K.M. Mehta, V. Mejia-Rodriguez, F. Mekonen, T. Melese, A. Melku, M. Meltzer, M. Memiah, P.T.N. Memish, Z.A. Mendoza, W. Mengistu, D.T. Mengistu, G. Mensah, G.A. Mereta, S.T. Meretoja, A. Meretoja, T.J. Mestrovic, T. Mezerji, N.M.G. Miazgowski, B. Miazgowski, T. Millear, A.I. Miller, T.R. Miltz, B. Mini, G.K. Mirarefin, M. Mirrakhimov, E.M. Misganaw, A.T. Mitchell, P.B. Mitiku, H. Moazen, B. Mohajer, B. Mohammad, K.A. Mohammadifard, N. Mohammadnia-Afrouzi, M. Mohammed, M.A. Mohammed, S. Mohebi, F. Moitra, M. Mokdad, A.H. Molokhia, M. Monasta, L. Moodley, Y. Moosazadeh, M. Moradi, G. Moradi-Lakeh, M. Moradinazar, M. Moraga, P. Morawska, L. Moreno Velásquez, I. Morgado-Da-Costa, J. Morrison, S.D. Moschos, M.M. Mousavi, S.M. Mruts, K.B. Muche, A.A. Muchie, K.F. Mueller, U.O. Muhammed, O.S. Mukhopadhyay, S. Muller, K. Mumford, J.E. Murhekar, M. Musa, J. Musa, K.I. Mustafa, G. Nabhan, A.F. Nagata, C. Naghavi, M. Naheed, A. Nahvijou, A. Naik, G. Naik, N. Najafi, F. Naldi, L. Nam, H.S. Nangia, V. Nansseu, J.R. Nascimento, B.R. Natarajan, G. Neamati, N. Negoi, I. Negoi, R.I. Neupane, S. Newton, C.R.J. Ngunjiri, J.W. Nguyen, A.Q. Nguyen, H.T. Nguyen, H.L.T. Nguyen, H.T. Nguyen, L.H. Nguyen, M. Nguyen, N.B. Nguyen, S.H. Nichols, E. Ningrum, D.N.A. Nixon, M.R. Nolutshungu, N. Nomura, S. Norheim, O.F. Noroozi, M. Norrving, B. Noubiap, J.J. Nouri, H.R. Nourollahpour Shiadeh, M. Nowroozi, M.R. Nsoesie, E.O. Nyasulu, P.S. Odell, C.M. Ofori-Asenso, R. Ogbo, F.A. Oh, I.-H. Oladimeji, O. Olagunju, A.T. Olagunju, T.O. Olivares, P.R. Olsen, H.E. Olusanya, B.O. Ong, K.L. Ong, S.K. Oren, E. Ortiz, A. Ota, E. Otstavnov, S.S. øverland, S. Owolabi, M.O. Mahesh, P.A. Pacella, R. Pakpour, A.H. Pana, A. Panda-Jonas, S. Parisi, A. Park, E.-K. Parry, C.D.H. Patel, S. Pati, S. Patil, S.T. Patle, A. Patton, G.C. Paturi, V.R. Paulson, K.R. Pearce, N. Pereira, D.M. Perico, N. Pesudovs, K. Pham, H.Q. Phillips, M.R. Pigott, D.M. Pillay, J.D. Piradov, M.A. Pirsaheb, M. Pishgar, F. Plana-Ripoll, O. Plass, D. Polinder, S. Popova, S. Postma, M.J. Pourshams, A. Poustchi, H. Prabhakaran, D. Prakash, S. Prakash, V. Purcell, C.A. Purwar, M.B. Qorbani, M. Quistberg, D.A. Radfar, A. Rafay, A. Rafiei, A. Rahim, F. Rahimi, K. Rahimi-Movaghar, A. Rahimi-Movaghar, V. Rahman, M. Ur Rahman, M.H. Rahman, M.A. Rahman, S.U. Rai, R.K. Rajati, F. Ram, U. Ranjan, P. Ranta, A. Rao, P.C. Rawaf, D.L. Rawaf, S. Reddy, K.S. Reiner, R.C. Reinig, N. Reitsma, M.B. Remuzzi, G. Renzaho, A.M.N. Resnikoff, S. Rezaei, S. Rezai, M.S. Ribeiro, A.L.P. Robinson, S.R. Roever, L. Ronfani, L. Roshandel, G. Rostami, A. Roth, G.A. Roy, A. Rubagotti, E. Sachdev, P.S. Sadat, N. Saddik, B. Sadeghi, E. Saeedi Moghaddam, S. Safari, H. Safari, Y. Safari-Faramani, R. Safdarian, M. Safi, S. Safiri, S. Sagar, R. Sahebkar, A. Sahraian, M.A. Sajadi, H.S. Salam, N. Salama, J.S. Salamati, P. Saleem, K. Saleem, Z. Salimi, Y. Salomon, J.A. Salvi, S.S. Salz, I. Samy, A.M. Sanabria, J. Sang, Y. Santomauro, D.F. Santos, I.S. Santos, J.V. Santric Milicevic, M.M. Sao Jose, B.P. Sardana, M. Sarker, A.R. Sarrafzadegan, N. Sartorius, B. Sarvi, S. Sathian, B. Satpathy, M. Sawant, A.R. Sawhney, M. Saxena, S. Saylan, M. Schaeffner, E. Schmidt, M.I. Schneider, I.J.C. Schöttker, B. Schwebel, D.C. Schwendicke, F. Scott, J.G. Sekerija, M. Sepanlou, S.G. Serván-Mori, E. Seyedmousavi, S. Shabaninejad, H. Shafieesabet, A. Shahbazi, M. Shaheen, A.A. Shaikh, M.A. Shams-Beyranvand, M. Shamsi, M. Shamsizadeh, M. Sharafi, H. Sharafi, K. Sharif, M. Sharif-Alhoseini, M. Sharma, M. Sharma, R. She, J. Sheikh, A. Shi, P. Shibuya, K. Shigematsu, M. Shiri, R. Shirkoohi, R. Shishani, K. Shiue, I. Shokraneh, F. Shoman, H. Shrime, M.G. Si, S. Siabani, S. Siddiqi, T.J. Sigfusdottir, I.D. Sigurvinsdottir, R. Silva, J.P. Silveira, D.G.A. Singam, N.S.V. Singh, J.A. Singh, N.P. Singh, V. Sinha, D.N. Skiadaresi, E. Slepak, E.L.N. Sliwa, K. Smith, D.L. Smith, M. Soares Filho, A.M. Sobaih, B.H. Sobhani, S. Sobngwi, E. Soneji, S.S. Soofi, M. Soosaraei, M. Sorensen, R.J.D. Soriano, J.B. Soyiri, I.N. Sposato, L.A. Sreeramareddy, C.T. Srinivasan, V. Stanaway, J.D. Stein, D.J. Steiner, C. Steiner, T.J. Stokes, M.A. Stovner, L.J. Subart, M.L. Sudaryanto, A. Sufiyan, M.B. Sunguya, B.F. Sur, P.J. Sutradhar, I. Sykes, B.L. Sylte, D.O. Tabarés-Seisdedos, R. Tadakamadla, S.K. Tadesse, B.T. Tandon, N. Tassew, S.G. Tavakkoli, M. Taveira, N. Taylor, H.R. Tehrani-Banihashemi, A. Tekalign, T.G. Tekelemedhin, S.W. Tekle, M.G. Temesgen, H. Temsah, M.-H. Temsah, O. Terkawi, A.S. Teweldemedhin, M. Thankappan, K.R. Thomas, N. Tilahun, B. To, Q.G. Tonelli, M. Topor-Madry, R. Topouzis, F. Torre, A.E. Tortajada-Girbés, M. Touvier, M. Tovani-Palone, M.R. Towbin, J.A. Tran, B.X. Tran, K.B. Troeger, C.E. Truelsen, T.C. Tsilimbaris, M.K. Tsoi, D. Tudor Car, L. Tuzcu, E.M. Ukwaja, K.N. Ullah, I. Undurraga, E.A. Unutzer, J. Updike, R.L. Usman, M.S. Uthman, O.A. Vaduganathan, M. Vaezi, A. Valdez, P.R. Varughese, S. Vasankari, T.J. Venketasubramanian, N. Villafaina, S. Violante, F.S. Vladimirov, S.K. Vlassov, V. Vollset, S.E. Vosoughi, K. Vujcic, I.S. Wagnew, F.S. Waheed, Y. Waller, S.G. Wang, Y. Wang, Y.-P. Weiderpass, E. Weintraub, R.G. Weiss, D.J. Weldegebreal, F. Weldegwergs, K.G. Werdecker, A. West, T.E. Whiteford, H.A. Widecka, J. Wijeratne, T. Wilner, L.B. Wilson, S. Winkler, A.S. Wiyeh, A.B. Wiysonge, C.S. Wolfe, C.D.A. Woolf, A.D. Wu, S. Wu, Y.-C. Wyper, G.M.A. Xavier, D. Xu, G. Yadgir, S. Yadollahpour, A. Yahyazadeh Jabbari, S.H. Yamada, T. Yan, L.L. Yano, Y. Yaseri, M. Yasin, Y.J. Yeshaneh, A. Yimer, E.M. Yip, P. Yisma, E. Yonemoto, N. Yoon, S.-J. Yotebieng, M. Younis, M.Z. Yousefifard, M. Yu, C. Zadnik, V. Zaidi, Z. Zaman, S.B. Zamani, M. Zare, Z. Zeleke, A.J. Zenebe, Z.M. Zhang, K. Zhao, Z. Zhou, M. Zodpey, S. Zucker, I. Vos, T. Murray, C.J.L. GBD 2017 Disease Injury Incidence Prevalence Collaborators
Abstract: Background: The Global Burden of Diseases, Injuries, and Risk Factors Study 2017 (GBD 2017) includes a comprehensive assessment of incidence, prevalence, and years lived with disability (YLDs) for 354 causes in 195 countries and territories from 1990 to 2017. Previous GBD studies have shown how the decline of mortality rates from 1990 to 2016 has led to an increase in life expectancy, an ageing global population, and an expansion of the non-fatal burden of disease and injury. These studies have also shown how a substantial portion of the world's population experiences non-fatal health loss with considerable heterogeneity among different causes, locations, ages, and sexes. Ongoing objectives of the GBD study include increasing the level of estimation detail, improving analytical strategies, and increasing the amount of high-quality data. Methods: We estimated incidence and prevalence for 354 diseases and injuries and 3484 sequelae. We used an updated and extensive body of literature studies, survey data, surveillance data, inpatient admission records, outpatient visit records, and health insurance claims, and additionally used results from cause of death models to inform estimates using a total of 68 781 data sources. Newly available clinical data from India, Iran, Japan, Jordan, Nepal, China, Brazil, Norway, and Italy were incorporated, as well as updated claims data from the USA and new claims data from Taiwan (province of China) and Singapore. We used DisMod-MR 2.1, a Bayesian meta-regression tool, as the main method of estimation, ensuring consistency between rates of incidence, prevalence, remission, and cause of death for each condition. YLDs were estimated as the product of a prevalence estimate and a disability weight for health states of each mutually exclusive sequela, adjusted for comorbidity. We updated the Socio-demographic Index (SDI), a summary development indicator of income per capita, years of schooling, and total fertility rate. Additionally, we calculated differences between male and female YLDs to identify divergent trends across sexes. GBD 2017 complies with the Guidelines for Accurate and Transparent Health Estimates Reporting. Findings: Globally, for females, the causes with the greatest age-standardised prevalence were oral disorders, headache disorders, and haemoglobinopathies and haemolytic anaemias in both 1990 and 2017. For males, the causes with the greatest age-standardised prevalence were oral disorders, headache disorders, and tuberculosis including latent tuberculosis infection in both 1990 and 2017. In terms of YLDs, low back pain, headache disorders, and dietary iron deficiency were the leading Level 3 causes of YLD counts in 1990, whereas low back pain, headache disorders, and depressive disorders were the leading causes in 2017 for both sexes combined. All-cause age-standardised YLD rates decreased by 3·9% (95% uncertainty interval [UI] 3·1-4·6) from 1990 to 2017; however, the all-age YLD rate increased by 7·2% (6·0-8·4) while the total sum of global YLDs increased from 562 million (421-723) to 853 million (642-1100). The increases for males and females were similar, with increases in all-age YLD rates of 7·9% (6·6-9·2) for males and 6·5% (5·4-7·7) for females. We found significant differences between males and females in terms of age-standardised prevalence estimates for multiple causes. The causes with the greatest relative differences between sexes in 2017 included substance use disorders (3018 cases [95% UI 2782-3252] per 100 000 in males vs 1400 [1279-1524] per 100 000 in females), transport injuries (3322 [3082-3583] vs 2336 [2154-2535]), and self-harm and interpersonal violence (3265 [2943-3630] vs 5643 [5057-6302]). Interpretation: Global all-cause age-standardised YLD rates have improved only slightly over a period spanning nearly three decades. However, the magnitude of the non-fatal disease burden has expanded globally, with increasing numbers of people who have a wide spectrum of conditions. A subset of conditions has remained globally pervasive since 1990, whereas other conditions have displayed more dynamic trends, with different ages, sexes, and geographies across the globe experiencing varying burdens and trends of health loss. This study emphasises how global improvements in premature mortality for select conditions have led to older populations with complex and potentially expensive diseases, yet also highlights global achievements in certain domains of disease and injury. Copyright © 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.
Published: 2018

15. Global, regional, and national age-sex-specific mortality and life expectancy, 1950-2017: A systematic analysis for the Global Burden of Disease Study 2017.

Author: Sartorius B., Venketasubramanian N., Vidavalur R., Villafaina S., Violante F.S., Vladimirov S.K., Vlassov V., Vollset S.E., Vos T., Vosoughi K., Vujcic I.S., Wagner G.R., Wagnew F.W.S., Waheed Y., Wang Y., Wang Y.-P., Wassie M.M., Weiderpass E., Weintraub R.G., Weiss D.J., Weiss J., Weldegebreal F., Weldegwergs K.G., Werdecker A., Westerman R., Whiteford H.A., Widecka J., Widecka K., Wijeratne T., Winkler A.S., Wiysonge C.S., Wolfe C.D.A., Wondemagegn S.A., Wu S., Wyper G.M.A., Xu G., Yadav R., Yakob B., Yamada T., Yan L.L., Yano Y., Yaseri M., Yasin Y.J., Ye P., Yearwood J.A., YentA1/4r G.K., Yeshaneh A., Yimer E.M., Yip P., Yisma E., Yonemoto N., Yoon S.-J., York H.W., Yotebieng M., Younis M.Z., Yousefifard M., Yu C., Zachariah G., Zadnik V., Zafar S., Zaidi Z., Zaman S.B., Zamani M., Zare Z., Zeeb H., Zeleke M.M., Zenebe Z.M., Zerfu T.A., Zhang K., Zhang X., Zhou M., Zhu J., Zodpey S., Zucker I., Zuhlke L.J.J., Lopez A.D., Gakidou E., Murray C.J.L., de Courten B., Thrift A.G., Dicker D., Nguyen G., Abate D., Abate K.H., Abay S.M., Abbafati C., Abbasi N., Abbastabar H., Abd-Allah F., Abdela J., Abdelalim A., Abdel-Rahman O., Abdi A., Abdollahpour I., Abdulkader R.S., Abdurahman A.A., Abebe H.T., Abebe M., Abebe Z., Abebo T.A., Aboyans V., Abraha H.N., Abrham A.R., Abu-Raddad L.J., Abu-Rmeileh N.M.E., Accrombessi M.M.K., Acharya P., Adebayo O.M., Adedeji I.A., Adedoyin R.A., Adekanmbi V., Adetokunboh O.O., Adhena B.M., Adhikari T.B., Adib M.G., Adou A.K., Adsuar J.C., Afarideh M., Afshin A., Agarwal G., Aggarwal R., Aghayan S.A., Agrawal S., Agrawal A., Ahmadi M., Ahmadi A., Ahmadieh H., Ahmed M.L.C.B., Ahmed S., Ahmed M.B., Aichour A.N., Aichour I., Aichour M.T.E., Akanda A.S., Akbari M.E., Akibu M., Akinyemi R.O., Akinyemiju T., Akseer N., Alahdab F., Al-Aly Z., Alam K., Alebel A., Aleman A.V., Alene K.A., Al-Eyadhy A., Ali R., Alijanzadeh M., Alizadeh-Navaei R., Aljunid S.M., Alkerwi A., Alla F., Allebeck P., Allen C.A., Alonso J., Al-Raddadi R.M., Alsharif U., Altirkawi K., Alvis-Guzman N., Amare A.T., Amini E., Ammar W., Amoako Y.A., Anber N.H., Andrei C.L., Androudi S., Animut M.D., Anjomshoa M., Anlay D.Z., Ansari H., Ansariadi A., Ansha M.G., Antonio C.A.T., Appiah S.C.Y., Aremu O., Areri H.A., ArnlAv J., Arora M., Artaman A., Aryal K.K., Asadi-Lari M., Asayesh H., Asfaw E.T., Asgedom S.W., Assadi R., Ataro Z., Atey T.M.M., Athari S.S., Atique S., Atre S.R., Atteraya M.S., Attia E.F., Ausloos M., Avila-Burgos L., Avokpaho E.F.G.A., Awasthi A., Awuah B., Ayala Quintanilla B.P., Ayele H.T., Ayele Y., Ayer R., Ayuk T.B., Azzopardi P.S., Azzopardi-Muscat N., Badali H., Badawi A., Balakrishnan K., Bali A.G., Banach M., Banstola A., Barac A., Barboza M.A., Barquera S., Barrero L.H., Basaleem H., Bassat Q., Basu A., Basu S., Baune B.T., Bazargan-Hejazi S., Bedi N., Beghi E., Behzadifar M., BACopyrightjot Y., Bekele B.B., Belachew A.B., Belay A.G., Belay E., Belay S.A., Belay Y.A., Bell M.L., Bello A.K., Bennett D.A., Bensenor I.M., Berhane A., Berman A.E., Bernabe E., Bernstein R.S., Bertolacci G.J., Beuran M., Beyranvand T., Bhala N., Bhatia E., Bhatt S., Bhattarai S., Bhaumik S., Bhutta Z.A., Biadgo B., Bijani A., Bikbov B., Bililign N., Bin Sayeed M.S., Birlik S.M., Birungi C., Bisanzio D., Biswas T., BjArge T., Bleyer A., Bora Basara B., Bose D., Bosetti C., Boufous S., Bourne R., Brady O.J., Bragazzi N.L., Brant L.C., Brazinova A., Breitborde N.J.K., Brenner H., Britton G., Brugha T., Burke K.E., Busse R., Butt Z.A., Cahuana-Hurtado L., Callender C.S.K.H., Campos-Nonato I.R., Campuzano Rincon J.C., Cano J., Car M., CArdenas R., Carreras G., Carrero J.J., Carter A., Carvalho F., CastaA+/-eda-Orjuela C.A., Castillo Rivas J., Castro F., CatalA-LApez F., Aavlin A., Cerin E., Chaiah Y., Champs A.P., Chang H.-Y., Chang J.-C., Chattopadhyay A., Chaturvedi P., Chen W., Chiang P.P.-C., Chimed-Ochir O., Chin K.L., Chisumpa V.H., Chitheer A., Choi J.-Y.J., Christensen H., Christopher D.J., Chung S.-C., Cicuttini F.M., 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T., Gebre A.K., Gebregergs G.B., Gebrehiwot T.T., Gebremedhin A.T., Gelano T.F., Gelaw Y.A., Geleijnse J.M., Genova-Maleras R., Gessner B.D., Getachew S., Gething P.W., Gezae K.E., Ghadami M.R., Ghadimi R., Ghasemi Falavarjani K., Ghasemi-Kasman M., Ghiasvand H., Ghimire M., Ghoshal A.G., Gill P.S., Gill T.K., Gillum R.F., Giussani G., Goenka S., Goli S., Gomez R.S., Gomez-Cabrera M.C., GAmez-DantACopyrights H., Gona P.N., Goodridge A., Gopalani S.V., Goto A., Goulart A.C., Goulart B.N.G., Grada A., Grosso G., Gugnani H.C., Guimaraes A.L.S., Guo Y., Gupta P.C., Gupta R., Gupta T., Gyawali B., Haagsma J.A., Hachinski V., Hafezi-Nejad N., Hagos T.B., Hailegiyorgis T.T., Hailu G.B., Haj-Mirzaian A., Hamadeh R.R., Hamidi S., Handal A.J., Hankey G.J., Harb H.L., Harikrishnan S., Haririan H., Haro J.M., Hasan M., Hassankhani H., Hassen H.Y., Havmoeller R., Hay R.J., Hay S.I., He Y., Hedayatizadeh-Omran A., Hegazy M.I., Heibati B., Heidari M., Hendrie D., Henok A., Henry N.J., Heredia-Pi I., Herteliu C., Heydarpour F., Heydarpour P., Heydarpour S., Hibstu D.T., Hoek H.W., Hole M.K., Homaie Rad E., Hoogar P., Horino M., Hosgood H.D., Hosseini S.M., Hosseinzadeh M., Hostiuc S., Hostiuc M., Hotez P.J., Hoy D.G., Hsairi M., Htet A.S., Hu G., Huang J.J., Husseini A., Hussen M.M., Hutfless S., Iburg K.M., Igumbor E.U., Ikeda C.T., Ilesanmi O.S., Iqbal U., Irvani S.S.N., Isehunwa O.O., Islam S.M.S., Islami F., Jahangiry L., Jahanmehr N., Jain R., Jain S.K., Jakovljevic M., James S.L., Javanbakht M., Jayaraman S., Jayatilleke A.U., Jee S.H., Jeemon P., Jha R.P., Jha V., Ji J.S., Johnson S.C., Jonas J.B., Joshi A., Jozwiak J.J., Jungari S.B., JA1/4risson M., Madhanraj K., Kabir Z., Kadel R., Kahsay A., Kahssay M., Kalani R., Kapil U., Karami M., Karami Matin B., Karch A., Karema C., Karimi N., Karimi S.M., Karimi-Sari H., Kasaeian A., Kassa G.M., Kassa T.D., Kassa Z.Y., Kassebaum N.J., Katibeh M., Katikireddi S.V., Kaul A., Kawakami N., Kazemeini H., Kazemi Z., Kazemi Karyani A., Prakash K.C., Kebede S., Keiyoro P.N., Kemp G.R., Kengne A.P., Keren A., Kereselidze M., Khader Y.S., Khafaie M.A., Khajavi A., Khalid N., Khalil I.A., Khan E.A., Khan G., Khan M.S., Khan M.A., Khang Y.-H., Khanna T., Khater M.M., Khatony A., Khazaie H., Khoja A.T., Khosravi A., Khosravi M.H., Khubchandani J., Kiadaliri A.A., Kibret G.D.D., Kim C.-I., Kim D., Kim J.Y., Kim Y.-E., Kimokoti R.W., Kinfu Y., Kinra S., Kisa A., Kissimova-Skarbek K., Kissoon N., KivimAki M., Kleber M.E., Knibbs L.D., Knudsen A.K.S., Kochhar S., Kokubo Y., Kolola T., Kopec J.A., Kosek M.N., Kosen S., Koul P.A., Koyanagi A., Kravchenko M.A., Krishan K., Krishnaswami S., Kuate Defo B., Kucuk Bicer B., Kudom A.A., Kuipers E.J., Kulikoff X.R., Kumar G.A., Kumar M., Kumar P., Kumsa F.A., Kutz M.J., Lad S.D., Lafranconi A., Lal D.K., Lalloo R., Lam H., Lami F.H., Lan Q., Langan S.M., Lansingh V.C., Lansky S., Larson H.J., Laryea D.O., Lassi Z.S., Latifi A., Lavados P.M., Laxmaiah A., Lazarus J.V., Lebedev G., Lee P.H., Leigh J., Leshargie C.T., Leta S., Levi M., Li S., Li Y., Li X., Liang J., Liang X., Liben M.L., Lim L.-L., Lim S.S., Limenih M.A., Linn S., Liu S., Liu Y., Lodha R., Logroscino G., Lonsdale C., Lorch S.A., Lorkowski S., Lotufo P.A., Lozano R., Lucas T.C.D., Lunevicius R., Lyons R.A., Ma S., Mabika C., Macarayan E.R.K., Mackay M.T., Maddison E.R., Maddison R., Madotto F., Magdy Abd El Razek H., Magdy Abd El Razek M., Maghavani D.P., Majdan M., Majdzadeh R., Majeed A., Malekzadeh R., Malik M.A., Malta D.C., Mamun A.A., Manamo W.A., Manda A.-L., Mansournia M.A., Mantovani L.G., Mapoma C.C., Marami D., Maravilla J.C., Marcenes W., Marina S., Martinez-Raga J., Martins S.C.O., Martins-Melo F.R., MArz W., Marzan M.B., Mashamba-Thompson T.P., Masiye F., Massenburg B.B., Maulik P.K., Mazidi M., McGrath J.J., McKee M., Mehata S., Mehendale S.M., Mehndiratta M.M., Mehrotra R., Mehta K.M., Mehta V., Mekonen T., Mekonnen T.C., Meles H.G., Meles K.G., Melese A., Melku M., Memiah P.T.N., Memish Z.A., Mendoza W., Mengistu D.T., Mengistu G., Mensah G.A., Mereta S.T., Meretoja A., Meretoja T.J., Mestrovic T., Mezgebe H.B., Miangotar Y., Miazgowski B., Miazgowski T., Miller T.R., Mini G.K., Mirica A., Mirrakhimov E.M., Misganaw A.T., Moazen B., Moges N.A., Mohammad K.A., Mohammadi M., Mohammadifard N., Mohammadi-Khanaposhtani M., Mohammadnia-Afrouzi M., Mohammed S., Mohammed M.A., Mohan V., Mokdad A.H., Molokhia M., Monasta L., Moradi G., Moradi M., Moradi-Lakeh M., Moradinazar M., Moraga P., Morawska L., Moreno VelAsquez I., Morgado-Da-costa J., Morrison S.D., Mosapour A., Moschos M.M., Mousavi S.M., Muche A.A., Muchie K.F., Mueller U.O., Mukhopadhyay S., Mullany E.C., Muller K., Murhekar M., Murphy T.B., Murthy G.V.S., Murthy S., Musa J., Musa K.I., Mustafa G., Muthupandian S., Nachega J.B., Nagel G., Naghavi M., Naheed A., Nahvijou A., Naik G., Nair S., Najafi F., Nangia V., Nansseu J.R., Nascimento B.R., Nawaz H., Ncama B.P., Neamati N., Negoi I., Negoi R.I., Neupane S., Newton C.R.J., Ngalesoni F.N., Ngunjiri J.W., Nguyen H.T., Nguyen L.H., Nguyen M., Nguyen T.H., Ningrum D.N.A., Nirayo Y.L., Nisar M.I., Nixon M.R., Nolutshungu N., Nomura S., Norheim O.F., Noroozi M., Norrving B., Noubiap J.J., Nouri H.R., Nourollahpour Shiadeh M., Nowroozi M.R., Nsoesie E.O., Nyasulu P.S., Ofori-Asenso R., Ogah O.S., Ogbo F.A., Oh I.-H., Okoro A., Oladimeji O., Olagunju A.T., Olagunju T.O., Olivares P.R., Olusanya B.O., Olusanya J.O., Ong S.K., Opio J.N., Oren E., Ortiz J.R., Ortiz A., Ota E., Otstavnov S.S., Averland S., Owolabi M.O., Oyekale A.S., Mahesh P.A., Pacella R., Pakhale S., Pakhare A.P., Pana A., Panda B.K., Panda-Jonas S., Pandey A.R., Pandian J.D., Parisi A., Park E.-K., Parry C.D.H., Parsian H., Patel S., Patle A., Patten S.B., Patton G.C., Paudel D., Pearce N., Peprah E.K., Pereira A., Pereira D.M., Perez K.M., Perico N., Pervaiz A., Pesudovs K., Petri W.A., Petzold M., Phillips M.R., Pigott D.M., Pillay J.D., Pirsaheb M., Pishgar F., Plass D., Polinder S., Pond C.D., Popova S., Postma M.J., Pourmalek F., Pourshams A., Poustchi H., Prabhakaran D., Prakash V., Prakash S., Prasad N., Qorbani M., Quistberg D.A., Radfar A., Rafay A., Rafiei A., Rahim F., Rahimi K., Rahimi-Movaghar A., Rahimi-Movaghar V., Rahman M., Ur Rahman M.H., Rahman M.A., Ur Rahman S., Rai R.K., Rajati F., Rajsic S., Raju S.B., Ram U., Ranabhat C.L., Ranjan P., Ranta A., Rasella D., Rawaf D.L., Rawaf S., Ray S.E., Razo-GarcA-a C., Rego M.A.S., Rehm J., Reiner R.C., Reinig N., Reis C., Remuzzi G., Renzaho A.M.N., Resnikoff S., Rezaei S., Rezaeian S., Rezai M.S., Riahi S.M., Ribeiro A.L.P., Riojas H., Rios-Blancas M.J., Roba K.T., Robinson S.R., Roever L., Ronfani L., Roshandel G., Roshchin D.O., Rostami A., Rothenbacher D., Rubagotti E., Ruhago G.M., Saadat S., Sabde Y.D., Sachdev P.S., Saddik B., Sadeghi E., Saeedi Moghaddam S., Safari H., Safari Y., Safari-Faramani R., Safdarian M., Safi S., Safiri S., Sagar R., Sahebkar A., Sahraian M.A., Sajadi H.S., Salahshoor M., Salam N., Salama J.S., Salamati P., Saldanha R.F., Salimi Y., Salimzadeh H., Salz I., Sambala E.Z., Samy A.M., Sanabria J., Sanchez-NiA+/-o M.D., Santos I.S., Santos J.V., Santric Milicevic M.M., Sao Jose B.P., Sardana M., Sarker A.R., Sarrafzadegan N., Sarvi S., Sathian B., Satpathy M., Savic M., Sawant A.R., Sawhney M., Saxena S., Sayyah M., Scaria V., Schaeffner E., Schelonka K., Schmidt M.I., Schneider I.J.C., SchAttker B., Schutte A.E., Schwebel D.C., Schwendicke F., Scott J.G., Sekerija M., Sepanlou S.G., ServAn-Mori E., Shabaninejad H., Shackelford K.A., Shafieesabet A., Shaheen A.A., Shaikh M.A., Shakir R.A., Shams-Beyranvand M., Shamsi M., Shamsizadeh M., Sharafi H., Sharafi K., Sharif M., Sharif-Alhoseini M., Sharma M., Sharma J., Sharma R., She J., Sheikh A., Sheth K.N., Shi P., Shibuya K., Shifa G.T., Shiferaw M.S., Shigematsu M., Shiri R., Shirkoohi R., Shiue I., Shokraneh F., Shrime M.G., Shukla S.R., Si S., Siabani S., Siddiqi T.J., Sigfusdottir I.D., Sigurvinsdottir R., Silpakit N., Silva D.A.S., Silva J.P., Silveira D.G.A., Singam N.S.V., Singh J.A., Singh V., Sinha A.P., Sinha D.N., Sitas F., Skirbekk V., Sliwa K., Soares Filho A.M., Sobaih B.H., Sobhani S., Soofi M., Soriano J.B., Soyiri I.N., Sposato L.A., Sreeramareddy C.T., Srinivasan V., Srivastava R.K., Starodubov V.I., Stathopoulou V., Steel N., Stein D.J., Steiner C., Stewart L.G., Stokes M.A., Sudaryanto A., Sufiyan M.B., Sulo G., Sunguya B.F., Sur P.J., Sutradhar I., Sykes B.L., Sylaja P.N., Sylte D.O., Szoeke C.E.I., TabarACopyrights-Seisdedos R., Tabuchi T., Tadakamadla S.K., Takahashi K., Tandon N., Tassew A.A., Tassew S.G., Tavakkoli M., Taveira N., Tawye N.Y., Tehrani-Banihashemi A., Tekalign T.G., Tekle M.G., Temesgen H., Temsah M.-H., Temsah O., Terkawi A.S., Teshale M.Y., Tessema B., Teweldemedhin M., Thakur J.S., Thankappan K.R., Thirunavukkarasu S., Thomas L.A., Thomas N., Tilahun B., To Q.G., Tobe-Gai R., Tonelli M., Topor-Madry R., Topouzis F., Torre A.E., Tortajada-GirbACopyrights M., Tovani-Palone M.R., Towbin J.A., Tran B.X., Tran K.B., Tripathi S., Tripathy S.P., Truelsen T.C., Truong N.T., Tsadik A.G., Tsilimparis N., Tudor Car L., Tuzcu E.M., Tyrovolas S., Ukwaja K.N., Ullah I., Usman M.S., Uthman O.A., Uzun S.B., Vaduganathan M., Vaezi A., Vaidya G., Valdez P.R., Varavikova E., Varughese S., Vasankari T.J., and Vasconcelos A.M.N.
Abstract: Background: Assessments of age-specifc mortality and life expectancy have been done by the UN Population Division, Department of Economics and Social Afairs (UNPOP), the United States Census Bureau, WHO, and as part of previous iterations of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD). Previous iterations of the GBD used population estimates from UNPOP, which were not derived in a way that was internally consistent with the estimates of the numbers of deaths in the GBD. The present iteration of the GBD, GBD 2017, improves on previous assessments and provides timely estimates of the mortality experience of populations globally. Method(s): The GBD uses all available data to produce estimates of mortality rates between 1950 and 2017 for 23 age groups, both sexes, and 918 locations, including 195 countries and territories and subnational locations for 16 countries. Data used include vital registration systems, sample registration systems, household surveys (complete birth histories, summary birth histories, sibling histories), censuses (summary birth histories, household deaths), and Demographic Surveillance Sites. In total, this analysis used 8259 data sources. Estimates of the probability of death between birth and the age of 5 years and between ages 15 and 60 years are generated and then input into a model life table system to produce complete life tables for all locations and years. Fatal discontinuities and mortality due to HIV/AIDS are analysed separately and then incorporated into the estimation. We analyse the relationship between age-specifc mortality and development status using the Socio-demographic Index, a composite measure based on fertility under the age of 25 years, education, and income. There are four main methodological improvements in GBD 2017 compared with GBD 2016: 622 additional data sources have been incorporated; new estimates of population, generated by the GBD study, are used; statistical methods used in diferent comp
Published: 2018

16. Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017.

Author: Servan-Mori E., Usman M.S., Uthman O.A., Vaduganathan M., Vaezi A., Vaidya G., Valdez P.R., Van Donkelaar A., Varavikova E., Vasankari T.J., Venketasubramanian N., Vidavalur R., Villafaina S., Violante F.S., Vladimirov S.K., Vlassov V., Vollmer S., Vollset S.E., Vos T., Vosoughi K., Vujcic I.S., Wagner G.R., Wagnew F.S., Waheed Y., Walson J.L., Wang Y., Wang Y.-P., Wassie M.M., Weiderpass E., Weintraub R.G., Weiss J., Weldegebreal F., Weldegwergs K.G., Werdecker A., Werkneh A.A., West T.E., Westerman R., Whisnant J.L., Whiteford H.A., Widecka J., Widecka K., Wijeratne T., Wilner L.B., Winkler A.S., Wiyeh A.B., Wiysonge C.S., Wolde H.F., Wolfe C.D.A., Wu S., Xavier D., Xu G., Xu R., Yadollahpour A., Jabbari S.H.Y., Yakob B., Yamada T., Yan L.L., Yano Y., Yaseri M., Yasin Y.J., Ye P., Yearwood J.A., Yeshaneh A., Yimer E.M., Yip P., Yirsaw B.D., Yisma E., Yonemoto N., Yonga G., Yoon S.-J., Yotebieng M., Younis M.Z., Yousefifard M., Yu C., Zaman S.B., Zamani M., Zare Z., Zavala-Arciniega L., Zegeye D.T., Zegeye E.A., Zeleke A.J., Zendehdel K., Zerfu T.A., Zhang A.L., Zhang X., Zhou M., Zhu J., Zimsen S.R.M., Zodpey S., Zoeckler L., Zucker I., Zuhlke L.J.J., Lim S.S., Murray C.J.L., De Courten B., Hughes C., Thrift A.G., Lozano R., Fullman N., Abate D., Abay S.M., Abbafati C., Abbasi N., Abbastabar H., Abd-Allah F., Abdela J., Abdelalim A., Abdel-Rahman O., Abdi A., Abdollahpour I., Abdulkader R.S., Abebe N.D., Abebe Z., Abejie A.N., Abera S.F., Abil O.Z., Aboyans V., Abraha H.N., Abrham A.R., Abu-Raddad L.J., Abu-Rmeileh N.M., Abyu G.Y., Accrombessi M.M.K., Acharya D., Acharya P., Adamu A.A., Adebayo O.M., Adedeji I.A., Adedoyin R.A., Adekanmbi V., Adetokunboh O.O., Adhena B.M., Adhikari T.B., Adib M.G., Adou A.K., Adsuar J.C., Afarideh M., Afshari M., Afshin A., Agarwal G., Aghayan S.A., Agius D., Agrawal A., Agrawal S., Ahmadi A., Ahmadi M., Ahmadieh H., Ahmed M.B., Ahmed S., Akalu T.Y., Akanda A.S., Akbari M.E., Akibu M., Akinyemi R.O., Akinyemiju T., Akseer N., Alahdab F., Al-Aly Z., Alam K., Alam T., Albujeer A., Alebel A., Alene K.A., Al-Eyadhy A., Alhabib S., Ali R., Alijanzadeh M., Alizadeh-Navaei R., Aljunid S.M., Alkerwi A., Alla F., Allebeck P., Allen C.A., Almasi A., Al-Maskari F., Al-Mekhlafi H.M., Alonso J., Al-Raddadi R.M., Alsharif U., Altirkawi K., Alvis-Guzman N., Amare A.T., Amenu K., Amini E., Ammar W., Anber N.H., Anderson J.A., Andrei C.L., Androudi S., Animut M.D., Anjomshoa M., Ansari H., Ansariadi A., Ansha M.G., Antonio C.A.T., Anwari P., Appiah L.T., Aremu O., Areri H.A., Arnlov J., Arora M., Aryal K.K., Asayesh H., Asfaw E.T., Asgedom S.W., Asghar R.J., Assadi R., Ataro Z., Atique S., Atre S.R., Atteraya M.S., Ausloos M., Avila-Burgos L., Avokpaho E.F.G.A., Awasthi A., Quintanilla B.P.A., Ayele H.T., Ayele Y., Ayer R., Azarpazhooh M.R., Azzopardi P.S., Azzopardi-Muscat N., Babalola T.K., Babazadeh A., Badali H., Badawi A., Balakrishnan K., Bali A.G., Banach M., Banerjee A., Banoub J.A.M., Banstola A., Barac A., Barboza M.A., Barker-Collo S.L., Barnighausen T.W., Barrero L.H., Barthelemy C.M., Bassat Q., Basu A., Basu S., Battista R.J., Baune B.T., Baynes H.W., Bazargan-Hejazi S., Bedi N., Beghi E., Behzadifar M., Bejot Y., Bekele B.B., Belachew A.B., Belay A.G., Belay S.A., Belay Y.A., Bell M.L., Bello A.K., Bennett D.A., Bensenor I.M., Benzian H., Berhane A., Berhe A.K., Berman A.E., Bernabe E., Bernstein R.S., Bertolacci G.J., Beuran M., Beyranvand T., Bhala N., Bhalla A., Bhansali A., Bhattarai S., Bhaumik S., Bhutta Z.A., Biadgo B., Biehl M.H., Bijani A., Bikbov B., Bililign N., Sayeed M.S.B., Birlik S.M., Birungi C., Bisanzio D., Biswas T., Bitew H., Bizuneh H., Bjertness E., Bobasa E.M., Boufous S., Bourne R., Bozorgmehr K., Bragazzi N.L., Brainin M., Brant L.C., Brauer M., Brazinova A., Breitborde N.J.K., Briant P.S., Britton G., Brugha T., Bukhman G., Busse R., Butt Z.A., Cahuana-Hurtado L., Callender C.S.K.H., Campos-Nonato I.R., Rincon J.C.C., Cano J., Car J., Car M., Cardenas R., Carrero J.J., Carter A., Carvalho F., Castaneda-Orjuela C.A., Rivas J.C., Castro F., Causey K., Cavlin A., Cercy K.M., Cerin E., Chaiah Y., Chalek J., Chang H.-Y., Chang J.-C., Chattopadhyay A., Chattu V.K., Chaturvedi P., Chiang P.P.-C., Chin K.L., Chisumpa V.H., Chitheer A., Choi J.-Y.J., Chowdhury R., Christensen H., Christopher D.J., Chung S.-C., Cicuttini F.M., Ciobanu L.G., Cirillo M., Claro R.M., Classen T.K.D., Cohen A.J., Collado-Mateo D., Cooper C., Cooper L.T., Cornaby L., Cortinovis M., Costa M., Cousin E., Cromwell E.A., Crowe C.S., Cunningham M., Daba A.K., Dadi A.F., Dandona L., Dandona R., Dang A.K., Dargan P.I., Daryani A., Das S.K., Das Gupta R., Das Neves J., Dasa T.T., Dash A.P., Davis A.C., Davitoiu D.V., Davletov K., Dayama A., De Leo D., Neve J.W.D., De Steur H., Degefa M.G., Degenhardt L., Degfie T.T., Deiparine S., Dellavalle R.P., Demoz G.T., Demtsu B., Denova-Gutierrez E., Deribe K., Dervenis N., Dessie G.A., Dey S., Dharmaratne S.D., Dhimal M., 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Hoogar P., Horita N., Hosgood H.D., Hosseini S.M., Hosseinzadeh M., Hostiuc M., Hostiuc S., Hotez P.J., Hoy D.G., Hsairi M., Hsiao T., Hu G., Huang J.J., Huynh C.K., Igumbor E.U., Ikeda C.T., Ilesanmi O.S., Iqbal U., Irvani S.S.N., Irvine C.M.S., Islam S.M.S., Islami F., Ivers R.Q., Izadi N., Jacobsen K.H., Jahangiry L., Jahanmehr N., Jain S.K., Jakovljevic M., Jalu M.T., Jamal A.A., James S.L., Jassal S.K., Javanbakht M., Jayatilleke A.U., Jeemon P., Jha R.P., Jha V., Ji J.S., Johnson C.O., Johnson S.C., Jonas J.B., Jonnagaddala J., Shushtari Z.J., Joshi A., Jozwiak J.J., Jungari S.B., Jurisson M., Madhanraj K., Kabir Z., Kadel R., Kahsay A., Kahssay M., Kalani R., Kapil U., Karami M., Matin B.K., Karanikolos M., Karimi N., Karimi S.M., Karimi-Sari H., Kasaeian A., Kassa D.H., Kassa G.M., Kassa T.D., Kassa Z.Y., Kassebaum N.J., Katikireddi S.V., Kaul A., Kawakami N., Kazemi Z., Karyani A.K., Kazi D.S., Prakash K.C., Kebede S., Keiyoro P.N., Kemmer L., Kemp G.R., Kengne A.P., Keren A., Kesavachandran C.N., Khader Y.S., Khafaei B., Khafaie M.A., Khajavi A., Khalid N., Khalil I.A., Khan E.A., Khan M.S., Khan M.A., Khang Y.-H., Khanna T., Khater M.M., Khatony A., Khazaeipour Z., Khazaie H., Khoja A.T., Khosravi A., Khosravi M.H., Khubchandani J., Kiadaliri A.A., Kiarie H.W., Kibret G.D., Kiirithio D.N., Kim D., Kim J.Y., Kim Y.-E., Kim Y.J., Kimokoti R.W., Kinfu Y., Kinra S., Kisa A., Kissimova-Skarbek K., Kissoon N., Kivimaki M., Kocarnik J.M., Kochhar S., Kokubo Y., Kolola T., Kopec J.A., Kosek M.N., Kosen S., Koul P.A., Koyanagi A., Kravchenko M.A., Krishan K., Krohn K.J., Defo B.K., Kucuk Bicer B., Kudom A.A., Kulikoff X.R., Kumar G.A., Kumar M., Kumar P., Kutz M.J., Kyu H.H., Lachat C., Lad D.P., Lad S.D., Lafranconi A., Lagat A.K., Lal D.K., Lalloo R., Lam H., Lami F.H., Lamichhane P., Lan Q., Lang J.J., Lansingh V.C., Lansky S., Larson H.J., Larsson A.O., Laryea D.O., Lassi Z.S., Latifi A., Lau K.M.-M., Laxmaiah A., Lazarus J.V., Leasher J.L., Lebedev G., Ledesma J.R., Lee J.B., Lee P.H., Leever A.T., Leigh J., Leinsalu M., Leshargie C.T., Leung J., Lewycka S., Li S., Li X., Li Y., Liang J., Liang X., Liben M.L., Lim L.-L., Limenih M.A., Linn S., Liu S., Liu Y., Lodha R., Logroscino G., Lopez A.D., Lorkowski S., Lotufo P.A., Lucchesi L.R., Lyons R.A., Macarayan E.R.K., Mackay M.T., Maddison E.R., Madotto F., Maghavani D.P., Magis-Rodriguez C., Mahotra N.B., Majdan M., Majdzadeh R., Majeed A., Malekzadeh R., Malta D.C., Mamun A.A., Manda A.-L., Mandarano-Filho L.G., Mangalam S., Manguerra H., Mansournia M.A., Mapoma C.C., Maravilla J.C., Marcenes W., Marks A., Martin R.V., Martins S.C.O., Martins-Melo F.R., Martopullo I., Mashamba-Thompson T.P., Massenburg B.B., Mathur M.R., Maulik P.K., Mazidi M., McAlinden C., McGrath J.J., McKee M., McMahon B.J., Mehata S., Mehndiratta M.M., Mehrotra R., Mehta K.M., Mehta V., Mejia-Rodriguez F., Mekonen T., Mekonnen T.C.C., Meles H.G., Melese A., Melku M., Memiah P.T.N., Memish Z.A., Mendoza W., Mengistu D.T., Mengistu G., Mensah G.A., Mensink G.B.M., Mereta S.T., Meretoja A., Meretoja T.J., Mestrovic T., Mezgebe H.B., Miazgowski B., Miazgowski T., Millear A.I., Miller T.R., Miller-Petrie M.K., Milne G.J., Mini G.K., Minnig S.P., Mirabi P., Mirarefin M., Mirrakhimov E.M., Misganaw A.T., Mitchell P.B., Moazen B., Moghadamnia A.A., Mohajer B., Mohammad K.A., Mohammadi M., Mohammadifard N., Mohammadnia-Afrouzi M., Mohammed M.A., Mohammed S., Mohan M.B.V., Mohan V., Mohebi F., Moitra M., Mokdad A.H., Molokhia M., Monasta L., Montanez J.C., Moosazadeh M., Moradi G., Moradi M., Moradi-Lakeh M., Moradinazar M., Moraga P., Morawska L., Morgado-da-Costa J., Morisaki N., Morrison S.D., Mosapour A., Moschos M.M., Mountjoy-Venning W.C., Mouodi S., Mousavi S.M., Muche A.A., Muchie K.F., Mueller U.O., Muhammed O.S.S., Mukhopadhyay S., Mullany E.C., Muller K., Mumford J.E., Murhekar M., Murthy G.V.S., Murthy S., Musa J., Musa K.I., Mustafa G., Muthupandian S., Nabhan A.F., Nachega J.B., Nagarajan 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Tanser F.C., Tassew A.A., Tassew S.G., Tavakkoli M., Taveira N., Tawye N.Y., Tehrani-Banihashemi A., Tekalign T.G., Tekle M.G., Temesgen H., Temsah M.-H., Temsah O., Terkawi A.S., Teshale M.Y., Teshome D.F., Tessema B., Teweldemedhin M., Thakur J.S., Thankappan K.R., Theis A., Thirunavukkarasu S., Thomas L.A., Thomas N., Thomson A.J., Tilahun B., To Q.G., Tobe-Gai R., Tonelli M., Topor-Madry R., Torre A.E., Tortajada-Girbes M., Tovani-Palone M.R., Towbin J.A., Tran B.X., Tran K.B., Tran T.T., Tripathy S.P., Troeger C.E., Truelsen T.C., Tsadik A.G., Car L.T., Tuzcu E.M., Tymeson H.D., Ukwaja K.N., Ullah I., and Updike R.L.
Abstract: Background: Efforts to establish the 2015 baseline and monitor early implementation of the UN Sustainable Development Goals (SDGs) highlight both great potential for and threats to improving health by 2030. To fully deliver on the SDG aim of "leaving no one behind", it is increasingly important to examine the health-related SDGs beyond national-level estimates. As part of the Global Burden of Diseases, Injuries, and Risk Factors Study 2017 (GBD 2017), we measured progress on 41 of 52 health-related SDG indicators and estimated the health-related SDG index for 195 countries and territories for the period 1990-2017, projected indicators to 2030, and analysed global attainment. Method(s): We measured progress on 41 health-related SDG indicators from 1990 to 2017, an increase of four indicators since GBD 2016 (new indicators were health worker density, sexual violence by non-intimate partners, population census status, and prevalence of physical and sexual violence [reported separately]). We also improved the measurement of several previously reported indicators. We constructed national-level estimates and, for a subset of health-related SDGs, examined indicator-level differences by sex and Socio-demographic Index (SDI) quintile. We also did subnational assessments of performance for selected countries. To construct the health-related SDG index, we transformed the value for each indicator on a scale of 0-100, with 0 as the 2.5th percentile and 100 as the 97.5th percentile of 1000 draws calculated from 1990 to 2030, and took the geometric mean of the scaled indicators by target. To generate projections through 2030, we used a forecasting framework that drew estimates from the broader GBD study and used weighted averages of indicator-specific and country-specific annualised rates of change from 1990 to 2017 to inform future estimates. We assessed attainment of indicators with defined targets in two ways: first, using mean values projected for 2030, and then using the prob
Published: 2018

17. Global, regional, and national incidence, prevalence, and years lived with disability for 354 Diseases and Injuries for 195 countries and territories, 1990-2017: A systematic analysis for the Global Burden of Disease Study 2017.

Author: She J., Thankappan K.R., Thomas N., Tilahun B., To Q.G., Tonelli M., Topor-Madry R., Topouzis F., Torre A.E., Tortajada-Girbes M., Touvier M., Tovani-Palone M.R., Towbin J.A., Tran B.X., Tran K.B., Troeger C.E., Truelsen T.C., Tsilimbaris M.K., Tsoi D., Tudor Car L., Tuzcu E.M., Ukwaja K.N., Ullah I., Undurraga E.A., Unutzer J., Updike R.L., Usman M.S., Uthman O.A., Vaduganathan M., Vaezi A., Valdez P.R., Varughese S., Vasankari T.J., Venketasubramanian N., Villafaina S., Violante F.S., Vladimirov S.K., Vlassov V., Vollset S.E., Vosoughi K., Vujcic I.S., Wagnew F.S., Waheed Y., Waller S.G., Wang Y., Wang Y.-P., Weiderpass E., Weintraub R.G., Weiss D.J., Weldegebreal F., Weldegwergs K.G., Werdecker A., West T.E., Whiteford H.A., Widecka J., Wijeratne T., Wilner L.B., Wilson S., Winkler A.S., Wiyeh A.B., Wiysonge C.S., Wolfe C.D.A., Woolf A.D., Wu S., Wu Y.-C., Wyper G.M.A., Xavier D., Xu G., Yadgir S., Yadollahpour A., Yahyazadeh Jabbari S.H., Yamada T., Yan L.L., Yano Y., Yaseri M., Yasin Y.J., Yeshaneh A., Yimer E.M., Yip P., Yisma E., Yonemoto N., Yoon S.-J., Yotebieng M., Younis M.Z., Yousefifard M., Yu C., Zadnik V., Zaidi Z., Zaman S.B., Zamani M., Zare Z., Zeleke A.J., Zenebe Z.M., Zhang K., Zhao Z., Zhou M., Zodpey S., Zucker I., Vos T., Murray C.J.L., De Courten B., Fox J., James S.L., Abate D., Abate K.H., Abay S.M., Abbafati C., Abbasi N., Abbastabar H., Abd-Allah F., Abdela J., Abdelalim A., Abdollahpour I., Abdulkader R.S., Abebe Z., Abera S.F., Abil O.Z., Abraha H.N., Abu-Raddad L.J., Abu-Rmeileh N.M.E., Accrombessi M.M.K., Acharya D., Acharya P., Ackerman I.N., Adamu A.A., Adebayo O.M., Adekanmbi V., Adetokunboh O.O., Adib M.G., Adsuar J.C., Afanvi K.A., Afarideh M., Afshin A., Agarwal G., Agesa K.M., Aggarwal R., Aghayan S.A., Agrawal S., Ahmadi A., Ahmadi M., Ahmadieh H., Ahmed M.B., Aichour A.N., Aichour I., Aichour M.T.E., Akinyemiju T., Akseer N., Al-Aly Z., Al-Eyadhy A., Al-Mekhlafi H.M., Al-Raddadi R.M., Alahdab F., Alam K., Alam T., Alashi A., Alavian S.M., Alene K.A., Alijanzadeh M., Alizadeh-Navaei R., Aljunid S.M., Alkerwi A., Alla F., Allebeck P., Alouani M.M.L., Altirkawi K., Alvis-Guzman N., Amare A.T., Aminde L.N., Ammar W., Amoako Y.A., Anber N.H., Andrei C.L., Androudi S., Animut M.D., Anjomshoa M., Ansha M.G., Antonio C.A.T., Anwari P., Arabloo J., Arauz A., Aremu O., Ariani F., Armoon B., Arnlov J., Arora A., Artaman A., Aryal K.K., Asayesh H., Asghar R.J., Ataro Z., Atre S.R., Ausloos M., Avila-Burgos L., Avokpaho E.F.G.A., Awasthi A., Ayala Quintanilla B.P., Ayer R., Azzopardi P.S., Babazadeh A., Badali H., Badawi A., Bali A.G., Ballesteros K.E., Ballew S.H., Banach M., Banoub J.A.M., Banstola A., Barac A., Barboza M.A., Barker-Collo S.L., Barnighausen T.W., Barrero L.H., Baune B.T., Bazargan-Hejazi S., Bedi N., Beghi E., Behzadifar M., Bejot Y., Belachew A.B., Belay Y.A., Bell M.L., Bello A.K., Bensenor I.M., Bernabe E., Bernstein R.S., Beuran M., Beyranvand T., Bhala N., Bhattarai S., Bhaumik S., Bhutta Z.A., Biadgo B., Bijani A., Bikbov B., Bilano V., Bililign N., Bin Sayeed M.S., Bisanzio D., Blacker B.F., Blyth F.M., Bou-Orm I.R., Boufous S., Bourne R., Brady O.J., Brainin M., Brant L.C., Brazinova A., Breitborde N.J.K., Brenner H., Briant P.S., Briggs A.M., Briko A.N., Britton G., Brugha T., Buchbinder R., Busse R., Butt Z.A., Cahuana-Hurtado L., Cano J., Cardenas R., Carrero J.J., Carter A., Carvalho F., Castaneda-Orjuela C.A., Castillo Rivas J., Castro F., Catala-Lopez F., Cercy K.M., Cerin E., Chaiah Y., Chang A.R., Chang H.-Y., Chang J.-C., Charlson F.J., Chattopadhyay A., Chattu V.K., Chaturvedi P., Chiang P.P.-C., Chin K.L., Chitheer A., Choi J.-Y.J., Chowdhury R., Christensen H., Christopher D.J., Cicuttini F.M., Ciobanu L.G., Cirillo M., Claro R.M., Collado-Mateo D., Cooper C., Coresh J., Cortesi P.A., Cortinovis M., Costa M., Cousin E., Criqui M.H., Cromwell E.A., Cross M., Crump J.A., Dadi A.F., Dandona L., Dandona R., Dargan P.I., Daryani A., Das Gupta R., 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H.W., Hoffman H.J., Hole M.K., Homaie Rad E., Hoogar P., Hosgood H.D., Hosseini S.M., Hosseinzadeh M., Hostiuc M., Hostiuc S., Hotez P.J., Hoy D.G., Hsairi M., Htet A.S., Hu G., Huang J.J., Huynh C.K., Iburg K.M., Ikeda C.T., Ileanu B., Ilesanmi O.S., Iqbal U., Irvani S.S.N., Irvine C.M.S., Islam S., Islami F., Jacobsen K.H., Jahangiry L., Jahanmehr N., Jain S.K., Jakovljevic M., Javanbakht M., Jayatilleke A.U., Jeemon P., Jha R.P., Jha V., Ji J.S., Johnson C.O., Jonas J.B., Jozwiak J.J., Jungari S.B., Jurisson M., Kabir Z., Kadel R., Kahsay A., Kalani R., Kanchan T., Karami M., Karami Matin B., Karch A., Karema C., Karimi N., Karimi S.M., Kasaeian A., Kassa D.H., Kassa G.M., Kassa T.D., Kassebaum N.J., Katikireddi S.V., Kawakami N., Kazemi Karyani A., Keighobadi M.M., Keiyoro P.N., Kemmer L., Kemp G.R., Kengne A.P., Keren A., Khader Y.S., Khafaei B., Khafaie M.A., Khajavi A., Khalil I.A., Khan E.A., Khan M.S., Khan M.A., Khang Y.-H., Khazaei M., Khoja A.T., Khosravi A., Khosravi M.H., Kiadaliri A.A., Kiirithio D.N., Kim C.-I., Kim D., Kim P., Kim Y.-E., Kim Y.J., Kimokoti R.W., Kinfu Y., Kisa A., Kissimova-Skarbek K., Kivimaki M., Knudsen A.K.S., Kocarnik J.M., Kochhar S., Kokubo Y., Kolola T., Kopec J.A., Kosen S., Kotsakis G.A., Koul P.A., Koyanagi A., Kravchenko M.A., Krishan K., Krohn K.J., Kuate Defo B., Kucuk Bicer B., Kumar G.A., Kumar M., Kyu H.H., Lad D.P., Lad S.D., Lafranconi A., Lalloo R., Lallukka T., Lami F.H., Lansingh V.C., Latifi A., Lau K.M.-M., Lazarus J.V., Leasher J.L., Ledesma J.R., Lee P.H., Leigh J., Leung J., Levi M., Lewycka S., Li S., Li Y., Liao Y., Liben M.L., Lim L.-L., Lim S.S., Liu S., Lodha R., Looker K.J., Lopez A.D., Lorkowski S., Lotufo P.A., Low N., Lozano R., Lucas T.C.D., Lucchesi L.R., Lunevicius R., Lyons R.A., Ma S., Macarayan E.R.K., Mackay M.T., Madotto F., Magdy Abd El Razek H., Magdy Abd El Razek M., Maghavani D.P., Mahotra N.B., Mai H.T., Majdan M., Majdzadeh R., Majeed A., Malekzadeh R., Malta D.C., Mamun A.A., Manda 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Abstract: Background: The Global Burden of Diseases, Injuries, and Risk Factors Study 2017 (GBD 2017) includes a comprehensive assessment of incidence, prevalence, and years lived with disability (YLDs) for 354 causes in 195 countries and territories from 1990 to 2017. Previous GBD studies have shown how the decline of mortality rates from 1990 to 2016 has led to an increase in life expectancy, an ageing global population, and an expansion of the non-fatal burden of disease and injury. These studies have also shown how a substantial portion of the world's population experiences non-fatal health loss with considerable heterogeneity among different causes, locations, ages, and sexes. Ongoing objectives of the GBD study include increasing the level of estimation detail, improving analytical strategies, and increasing the amount of high-quality data. Method(s): We estimated incidence and prevalence for 354 diseases and injuries and 3484 sequelae. We used an updated and extensive body of literature studies, survey data, surveillance data, inpatient admission records, outpatient visit records, and health insurance claims, and additionally used results from cause of death models to inform estimates using a total of 68 781 data sources. Newly available clinical data from India, Iran, Japan, Jordan, Nepal, China, Brazil, Norway, and Italy were incorporated, as well as updated claims data from the USA and new claims data from Taiwan (province of China) and Singapore. We used DisMod-MR 2.1, a Bayesian meta-regression tool, as the main method of estimation, ensuring consistency between rates of incidence, prevalence, remission, and cause of death for each condition. YLDs were estimated as the product of a prevalence estimate and a disability weight for health states of each mutually exclusive sequela, adjusted for comorbidity. We updated the Socio-demographic Index (SDI), a summary development indicator of income per capita, years of schooling, and total fertility rate. Additionally, we
Published: 2018

18. Outcomes of multidrug resistant tuberculosis treatment among human immunodeficiency virus co-infected patients taking anti-retroviral treatment at Sizwe Tropical Disease Hospital Johannesburg, South Africa

Author: Umanah, T., primary, Ncayiyana, J., additional, Padanilam, X., additional, and Nyasulu, P.S., additional
Published: 2016
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19. Factors associated with high HIV related stigma among commuter populations in Johannesburg inner city, South Africa

Author: Nyasulu, P.S., primary, Tshuma, N., additional, Muloongo, K., additional, and Chimoyi, L., additional
Published: 2016
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20. Mapping disparities in education across low- and middle-income countries

Author: Lauren E. Schaeffer, Belay Tessema, Reza Malekzadeh, Olatunde Aremu, Mehdi Hosseinzadeh, Milena M Santric Milicevic, Seyyed Meysam Mousavi, Azeem Majeed, Badr Hasan Sobaih, Jalal Arabloo, Philimon Gona, Aliasghar Ahmad Kiadaliri, Mostafa Qorbani, Fatemeh Rajati, Ipsita Sutradhar, Giuseppe Remuzzi, Babak Eshrati, Olufemi Ajumobi, Lauren Woyczynski, Parul Puri, Vinay Nangia, Guoqing Hu, Yousef Khader, Suzanne Barker-Collo, Hamideh Salimzadeh, Félix Carvalho, Yun Jin Kim, Moslem Soofi, Ali Bijani, Shanshan Li, Catalina Liliana Andrei, Ali Kazemi Karyani, Mehran Asadi-Aliabadi, Andrea Sylvia Winkler, Arya Haj-Mirzaian, Maziar Moradi-Lakeh, Farnam Mohebi, Mohamad-Hani Temsah, Kala M. Mehta, Simon I. Hay, Benjamin B. Massenburg, Sanjay Zodpey, Tuomo J. Meretoja, Ireneous N. Soyiri, Bach Xuan Tran, George C Patton, Kavumpurathu Raman Thankappan, Engida Yisma, Vasily Vlassov, Samer Hamidi, Ghulam Mustafa, André Faro, Eduarda Fernandes, Chandrashekhar T Sreeramareddy, Rajat Gupta, Shirin Djalalinia, Dina Nur Anggraini Ningrum, Sheikh Mohammed Shariful Islam, Juan Sanabria, Leonardo Roever, Dayane Gabriele Alves Silveira, Samad Azari, Vahid Alipour, Gabrielle B. Britton, Luca Ronfani, Rosario Cárdenas, Maarten J. Postma, Hamid Yimam Hassen, Pn Sylaja, Brijesh Sathian, Paul S. F. Yip, Vegard Skirbekk, Chhabi Lal Ranabhat, Paramjit Gill, Walter Mendoza, Lorenzo Monasta, Dara K. Mohammad, Naznin Hossain, Dhirendra N Sinha, Ali H. Mokdad, Aziz Rezapour, Megan F. Schipp, Ziyad Al-Aly, Takeshi Fukumoto, Kebede Deribe, Paula Moraga, Mohammad Ebrahimi Kalan, Ai Koyanagi, Andre M. N. Renzaho, Cyrus Cooper, Ghobad Moradi, Ruth W Kimokoti, Swayam Prakash, Rafael Tabarés-Seisdedos, Zahra Jorjoran Shushtari, Zemenu Tadesse Tessema, Amir Radfar, Jean Jacques Noubiap, Emmanuela Gakidou, Mahdi Afshari, Suleman Atique, Reza Majdzadeh, Kiomars Sharafi, Seyed-Mohammad Fereshtehnejad, Foad Abd-Allah, Zahid A Butt, Beruk Berhanu Desalegn, Ruxandra Irina Negoi, Marek Majdan, Yoshan Moodley, Jianrong Zhang, Farid Najafi, Aso Mohammad Darwesh, Benn Sartorius, Amber Sligar, Nicole Davis Weaver, Naohiro Yonemoto, Jacob Olusegun Olusanya, Olayinka Stephen Ilesanmi, Neeraj Bedi, Suraj Bhattarai, Sadaf G. Sepanlou, Francisco Rogerlandio Martins-Melo, Malihe Nourollahpour Shiadeh, Bernardo Hernández Prado, Masood Ali Shaikh, Khalid A Altirkawi, Carlos Rios-Gonzalez, Claudiu Herteliu, Jason B. Hall, Irina Filip, Abdullah Sulieman Terkawi, Sojib Bin Zaman, Nathaniel J Henry, Eleonora Dubljanin, Jasvinder A. Singh, Pushpendra Kumar, Akram Pourshams, Jung-Chen Chang, Irfan Ullah, Lorainne Tudor Car, Franz Castro, George A. Mensah, Delia Hendrie, Mehran Shams-Beyranvand, Zulfiqar A Bhutta, Jaifred Christian F. Lopez, Laura Dwyer-Lindgren, Lee Ling Lim, Charles D.A. Wolfe, Adnan Kisa, Seyed Sina Naghibi Irvani, Alaa Badawi, Bolajoko O. Olusanya, Tomohide Yamada, Gholamreza Roshandel, Jonathan F. Mosser, Jose A. Garcia, Andre Rodrigues Duraes, Mohammadreza Amiresmaili, Krittika Bhattacharyya, Yuan-Pang Wang, Sebastian Vollmer, Felix Akpojene Ogbo, Birkneh Tilahun Tadesse, Mihajlo Jakovljevic, Songhomitra Panda-Jonas, Paul H. Lee, Michael Collison, Sanghamitra Pati, Aziz Sheikh, Kalkidan Hassen Abate, Anthony Barnett, Ejaz Ahmad Khan, Michael A. Cork, Meghnath Dhimal, Norberto Perico, Francesco Saverio Violante, Daniel N. Kiirithio, Ted R. Miller, Arundhati R. Sawant, Olalekan A. Uthman, Kewal Krishan, Ashish Awasthi, Anthony Masaka, Katherine F. Wilson, Padukudru Anand Mahesh, Roy Burstein, Amir Kasaeian, Yuming Guo, Peter Nyasulu, Chuanhua Yu, Pascual R. Valdez, Josephine W. Ngunjiri, Vipin Gupta, Tomislav Mestrovic, Long Hoang Nguyen, Neda Izadi, Faris Lami, Marcos Roberto Tovani-Palone, Azin Nahvijou, Jun She, Christopher J L Murray, Krishna K. Aryal, Payman Salamati, Mona M. Khater, Rajeev Gupta, Robert Reiner, Mustafa Z. Younis, Ali Rostami, Duduzile Ndwandwe, Obinna Onwujekwe, Manasi Kumar, Nafis Sadat, Nahla Anber, Joan B. Soriano, Victor Adekanmbi, John C. Wilkinson, Babak Moazen, Andrew T Olagunju, Nicholas Graetz, Andualem Henok, Mina Anjomshoa, Boris Bikbov, Melaku Desta, Yahya Safari, Jan-Walter De Neve, Carlos A Castañeda-Orjuela, Mohammad Fareed, Ayman Grada, Eduardo Ortiz-Panozo, Rajesh Sharma, Beatriz Paulina Ayala Quintanilla, Enrico Rubagotti, John S. Ji, Mika Shigematsu, Fakher Rahim, Randah R. Hamadeh, G. K. Mini, Yasir Waheed, Meghdad Pirsaheb, Yousef Veisani, Daniel Diaz, Adrian Pana, Salman Rawaf, Ehsan Sadeghi, Yahya Salimi, Joseph Adel Mattar Banoub, Carl Abelardo T. Antonio, Morteza Abdullatif Khafaie, David M. Pigott, Fares Alahdab, Vafa Rahimi-Movaghar, Anbissa Muleta Senbeta, Tomi Akinyemiju, Damaris K. Kinyoki, Morteza Shamsizadeh, Ziad El-Khatib, Abdallah M. Samy, Roman Topor-Madry, Farah Daoud, Cuong Tat Nguyen, Aubrey J. Levine, Sameer Vali Gopalani, Ravi Prakash Jha, Mesfin Tadese Dinberu, Shafiu Mohammed, Simon Øverland, David Laith Rawaf, Arvin Haj-Mirzaian, Satar Rezaei, Oladimeji Adebayo, Nasir Salam, Mohammad Ali Mansournia, Rajesh Sagar, Alex Yeshaneh, Michael K. Hole, Agus Sudaryanto, Yunquan Zhang, Mahbobeh Faramarzi, Natalia V. Bhattacharjee, Aniruddha Deshpande, Soewarta Kosen, Mahmoud Yousefifard, Jacek Jerzy Jozwiak, Mehedi Hasan, Shane D. Morrison, Erkin M. Mirrakhimov, Marcel Ausloos, Ionut Negoi, Jacqueline Elizabeth Alcalde Rabanal, Barthelemy Kuate Defo, Giang Thu Vu, Lucas Earl, Doris D. V. Ortega-Altamirano, Yu Liao, Peter Njenga Keiyoro, Tanuj Kanchan, Chandrasekharan Nair Kesavachandran, Mu'awiyyah Babale Sufiyan, Mohammad Hifz Ur Rahman, Lidia Morawska, Tiffany K. Gill, Manisha Dubey, David C. Schwebel, Jost B. Jonas, Ester Cerin, Mehran Alijanzadeh, Florian Fischer, Stefan Listl, Benjamin K. Mayala, Mahmood Moosazadeh, Soraya Siabani, Derrick A Bennett, Collaborators, Local Burden of Disease Educational Attainment, Institute for Molecular Medicine Finland, HUS Comprehensive Cancer Center, Clinicum, Helsinki University Hospital Area, University of Helsinki, Local Burden Dis Educ Attainment C, Graetz N., Woyczynski L., Wilson K.F., Hall J.B., Abate K.H., Abd-Allah F., Adebayo O.M., Adekanmbi V., Afshari M., Ajumobi O., Akinyemiju T., Alahdab F., Al-Aly Z., Rabanal J.E.A., Alijanzadeh M., Alipour V., Altirkawi K., Amiresmaili M., Anber N.H., Andrei C.L., Anjomshoa M., Antonio C.A.T., Arabloo J., Aremu O., Aryal K.K., Asadi-Aliabadi M., Atique S., Ausloos M., Awasthi A., Quintanilla B.P.A., Azari S., Badawi A., Banoub J.A.M., Barker-Collo S.L., Barnett A., Bedi N., Bennett D.A., Bhattacharjee N.V., Bhattacharyya K., Bhattarai S., Bhutta Z.A., Bijani A., Bikbov B., Britton G., Burstein R., Butt Z.A., Cardenas R., Carvalho F., Castaneda-Orjuela C.A., Castro F., Cerin E., Chang J.-C., Collison M.L., Cooper C., Cork M.A., Daoud F., Das Gupta R., Weaver N.D., De Neve J.-W., Deribe K., Desalegn B.B., Deshpande A., Desta M., Dhimal M., Diaz D., Dinberu M.T., Djalalinia S., Dubey M., Dubljanin E., Duraes A.R., Dwyer-Lindgren L., Earl L., Kalan M.E., El-Khatib Z., Eshrati B., Faramarzi M., Fareed M., Faro A., Fereshtehnejad S.-M., Fernandes E., Filip I., Fischer F., Fukumoto T., Garcia J.A., Gill P.S., Gill T.K., Gona P.N., Gopalani S.V., Grada A., Guo Y., Gupta R., Gupta V., Haj-Mirzaian A., Hamadeh R.R., Hamidi S., Hasan M., Hassen H.Y., Hendrie D., Henok A., Henry N.J., Prado B.H., Herteliu C., Hole M.K., Hossain N., Hosseinzadeh M., Hu G., Ilesanmi O.S., Irvani S.S.N., Islam S.M.S., Izadi N., Jakovljevic M., Jha R.P., Ji J.S., Jonas J.B., Shushtari Z.J., Jozwiak J.J., Kanchan T., Kasaeian A., Karyani A.K., Keiyoro P.N., Kesavachandran C.N., Khader Y.S., Khafaie M.A., Khan E.A., Khater M.M., Kiadaliri A.A., Kiirithio D.N., Kim Y.J., Kimokoti R.W., Kinyoki D.K., Kisa A., Kosen S., Koyanagi A., Krishan K., Defo B.K., Kumar M., Kumar P., Lami F.H., Lee P.H., Levine A.J., Li S., Liao Y., Lim L.-L., Listl S., Lopez J.C.F., Majdan M., Majdzadeh R., Majeed A., Malekzadeh R., Mansournia M.A., Martins-Melo F.R., Masaka A., Massenburg B.B., Mayala B.K., Mehta K.M., Mendoza W., Mensah G.A., Meretoja T.J., Mestrovic T., Miller T.R., Mini G.K., Mirrakhimov E.M., Moazen B., Mohammad D.K., Darwesh A.M., Mohammed S., Mohebi F., Mokdad A.H., Monasta L., Moodley Y., Moosazadeh M., Moradi G., Moradi-Lakeh M., Moraga P., Morawska L., Morrison S.D., Mosser J.F., Mousavi S.M., Murray C.J.L., Mustafa G., Nahvijou A., Najafi F., Nangia V., Ndwandwe D.E., Negoi I., Negoi R.I., Ngunjiri J.W., Nguyen C.T., Nguyen L.H., Ningrum D.N.A., Noubiap J.J., Shiadeh M.N., Nyasulu P.S., Ogbo F.A., Olagunju A.T., Olusanya B.O., Olusanya J.O., Onwujekwe O.E., Ortega-Altamirano D.D.V., Ortiz-Panozo E., Overland S., Mahesh P.A., Pana A., Panda-Jonas S., Pati S., Patton G.C., Perico N., Pigott D.M., Pirsaheb M., Postma M.J., Pourshams A., Prakash S., Puri P., Qorbani M., Radfar A., Rahim F., Rahimi-Movaghar V., Rahman M.H.U., Rajati F., Ranabhat C.L., Rawaf D.L., Rawaf S., Reiner R.C., Remuzzi G., Renzaho A.M.N., Rezaei S., Rezapour A., Rios-Gonzalez C., Roever L., Ronfani L., Roshandel G., Rostami A., Rubagotti E., Sadat N., Sadeghi E., Safari Y., Sagar R., Salam N., Salamati P., Salimi Y., Salimzadeh H., Samy A.M., Sanabria J., Santric Milicevic M.M., Sartorius B., Sathian B., Sawant A.R., Schaeffer L.E., Schipp M.F., Schwebel D.C., Senbeta A.M., Sepanlou S.G., Shaikh M.A., Shams-Beyranvand M., Shamsizadeh M., Sharafi K., Sharma R., She J., Sheikh A., Shigematsu M., Siabani S., Silveira D.G.A., Singh J.A., Sinha D.N., Skirbekk V., Sligar A., Sobaih B.H., Soofi M., Soriano J.B., Soyiri I.N., Sreeramareddy C.T., Sudaryanto A., Babale Sufiyan M., Sutradhar I., Sylaja P., Tabares-Seisdedos R., Tadesse B.T., Temsah M.-H., Terkawi A.S., Tessema B., Tessema Z.T., Thankappan K.R., Topor-Madry R., Tovani-Palone M.R., Tran B.X., Car L.T., Ullah I., Uthman O.A., Valdez P.R., Veisani Y., Violante F.S., Vlassov V., Vollmer S., Thu Vu G., Waheed Y., Wang Y.-P., Wilkinson J.C., Winkler A.S., Wolfe C.D.A., Yamada T., Yeshaneh A., Yip P., Yisma E., Yonemoto N., Younis M.Z., Yousefifard M., Yu C., Bin Zaman S., Zhang J., Zhang Y., Zodpey S., Gakidou E., Hay S.I., Graetz, Nicholas, Woyczynski, Lauren, Wilson, Katherine F, Hall, Jason B, Yisma, Engida, Hay, Simon I, Local Burden of Disease Educational Attainment Collaborators, Microbes in Health and Disease (MHD), Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET), and Value, Affordability and Sustainability (VALUE)
Subjects: Male, ATTAINMENT, Health Status, Disease, education, low- and middle-income countries, 0302 clinical medicine, WORLD, gender, Global health, risk factors, 030212 general & internal medicine, Aetiology, 10. No inequality, media_common, Developing world, Pediatric, Multidisciplinary, 1. No poverty, Multidisciplinary Sciences, Geography, Science & Technology - Other Topics, Female, HEALTH, developing world, social and economic factors, Engineering sciences. Technology, disparitie, AFRICA, medicine.medical_specialty, Inequality, General Science & Technology, media_common.quotation_subject, MODELS, Developing country, Local Burden of Disease Educational Attainment Collaborators, Article, Healthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18], Education, 03 medical and health sciences, 2.3 Psychological, medicine, Humans, Society, Social determinants of health, Developing Countries, Science & Technology, Equity (economics), MORTALITY, Public health, Bayes Theorem, Educational attainment, 3141 Health care science, society, Good Health and Well Being, Risk factors, Socioeconomic Factors, Demographic economics, 030217 neurology & neurosurgery
Abstract: Educational attainment is an important social determinant of maternal, newborn, and child health1–3. As a tool for promoting gender equity, it has gained increasing traction in popular media, international aid strategies, and global agenda-setting4–6. The global health agenda is increasingly focused on evidence of precision public health, which illustrates the subnational distribution of disease and illness7,8; however, an agenda focused on future equity must integrate comparable evidence on the distribution of social determinants of health9–11. Here we expand on the available precision SDG evidence by estimating the subnational distribution of educational attainment, including the proportions of individuals who have completed key levels of schooling, across all low- and middle-income countries from 2000 to 2017. Previous analyses have focused on geographical disparities in average attainment across Africa or for specific countries, but—to our knowledge—no analysis has examined the subnational proportions of individuals who completed specific levels of education across all low- and middle-income countries12–14. By geolocating subnational data for more than 184 million person-years across 528 data sources, we precisely identify inequalities across geography as well as within populations., Analyses of the proportions of individuals who have completed key levels of schooling across all low- and middle-income countries from 2000 to 2017 reveal inequalities across countries as well as within populations.
Published: 2020

21. Mapping child growth failure across low- and middle-income countries

Author: Kinyoki D, Osgood-Zimmerman A, Pickering B, Schaeffer L, Marczak L, Lazzar-Atwood A, Collison M, Henry N, Abebe Z, Adamu A, Adekanmbi V, Ahmadi K, Ajumobi O, Al-Eyadhy A, Al-Raddadi R, Alahdab F, Alijanzadeh M, Alipour V, Altirkawi K, Amini S, Andrei C, Antonio C, Arabloo J, Aremu O, Asadi-Aliabadi M, Atique S, Ausloos M, Avila M, Awasthi A, Quintanilla B, Azari S, Badawi A, Barnighausen T, Bassat Q, Baye K, Bedi N, Bekele B, Bell M, Bhattacharjee N, Bhattacharyya K, Bhattarai S, Bhutta Z, Biadgo B, Bikbov B, Briko A, Britton G, Burstein R, Butt Z, Car J, Castaneda-Orjuela C, Castro F, Cerin E, Chipeta M, Chu D, Cork M, Cromwell E, Cuevas-Nasu L, Dandona L, Dandona R, Daoud F, Das Gupta R, Weaver N, De Leo D, De Neve J, Deribe K, Desalegn B, Deshpande A, Desta M, Diaz D, Dinberu M, Doku D, Dubey M, Duraes A, Dwyer-Lindgren L, Earl L, Effiong A, Zaki M, El Tantawi M, El-Khatib Z, Eshrati B, Fareed M, Faro A, Fereshtehnejad S, Filip I, Fischer F, Foigt N, Folayan M, Fukumoto T, Gebrehiwot T, Gezae K, Ghajar A, Gill P, Gona P, Gopalani S, Grada A, Guo Y, Haj-Mirzaian A, Hall J, Hamidi S, Henok A, Prado B, Herrero M, Herteliu C, Hoang C, Hole M, Hossain N, Hosseinzadeh M, Hu G, Islam S, Jakovljevic M, Jha R, Jonas J, Jozwiak J, Kahsay A, Kanchan T, Karami M, Kasaeian A, Khader Y, Khan E, Khater M, Kim Y, Kimokoti R, Kisa A, Kochhar S, Kosen S, Koyanagi A, Krishan K, Defo B, Kumar G, Kumar M, Lad S, Lami F, Lee P, Levine A, Li S, Linn S, Lodha R, Abd El Razek H, Abd El Razek M, Majdan M, Majeed A, Malekzadeh R, Malta D, Mamun A, Mansournia M, Martins-Melo F, Masaka A, Massenburg B, Mayala B, Mejia-Rodriguez F, Melku M, Mendoza W, Mensah G, Miazgowski T, Miller T, Mini G, Mirrakhimov E, Moazen B, Darwesh A, Mohammed S, Mohebi F, Mokdad A, Moodley Y, Moradi G, Moradi-Lakeh M, Moraga P, Morrison S, Mosser J, Mousavi S, Mueller U, Murray C, Mustafa G, Naderi M, Naghavi M, Najafi F, Nangia V, Ndwandwe D, Negoi I, Ngunjiri J, Nguyen H, Nguyen L, Nguyen S, Nie J, Nnaji C, Noubiap J, Shiadeh M, Nyasulu P, Ogbo F, Olagunju A, Olusanya B, Olusanya J, Ortiz-Panozo E, Otstavnov S, Mahesh P, Pana A, Pandey A, Pati S, Patil S, Patton G, Perico N, Pigott D, Pirsaheb M, Piwoz E, Postma M, Pourshams A, Prakash S, Quintana H, Radfar A, Rafiei A, Rahimi-Movaghar V, Rai R, Rajati F, Rawaf D, Rawaf S, Rawat R, Remuzzi G, Renzaho A, Rios-Gonzalez C, Roever L, Ross J, Rostami A, Sadat N, Safari Y, Safdarian M, Sahebkar A, Salam N, Salamati P, Salimi Y, Salimzadeh H, Samy A, Sartorius B, Sathian B, Schipp M, Schwebel D, Senbeta A, Sepanlou S, Shaikh M, Levy T, Shamsi M, Sharafi K, Sharma R, Sheikh A, Shil A, Silva D, Singh J, Sinha D, Soofi M, Sudaryanto A, Sufiyan M, Tabares-Seisdedos R, Tadesse B, Temsah M, Terkawi A, Tessema Z, Thorne-Lyman A, Tovani-Palone M, Tran B, Tran K, Ullah I, Uthman O, Vaezghasemi M, Vaezi A, Valdez P, Vanderheide J, Veisani Y, Violante F, Vlassov V, Vu G, Vu L, Waheed Y, Walson J, Wang Y, Wangia E, Werdecker A, Xu G, Yamada T, Yisma E, Yonemoto N, Younis M, Yousefifard M, Yu C, Bin Zaman S, Zamani M, Zhang Y, Kassebaum N, Hay S, Local Burden Dis Child Growth Fail, Public Health, Microbes in Health and Disease (MHD), Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET), Value, Affordability and Sustainability (VALUE), Kinyoki, Damaris K, Osgood-Zimmerman, Aaron E, Pickering, Brandon V, Schaeffer, Lauren E, Yisma, Engida, Hay, Simon I, Local Burden of Disease Child Growth Failure Collaborators, Kinyoki D.K., Osgood-Zimmerman A.E., Pickering B.V., Schaeffer L.E., Marczak L.B., Lazzar-Atwood A., Collison M.L., Henry N.J., Abebe Z., Adamu A.A., Adekanmbi V., Ahmadi K., Ajumobi O., Al-Eyadhy A., Al-Raddadi R.M., Alahdab F., Alijanzadeh M., Alipour V., Altirkawi K., Amini S., Andrei C.L., Antonio C.A.T., Arabloo J., Aremu O., Asadi-Aliabadi M., Atique S., Ausloos M., Avila M., Awasthi A., Quintanilla B.P.A., Azari S., Badawi A., Barnighausen T.W., Bassat Q., Baye K., Bedi N., Bekele B.B., Bell M.L., Bhattacharjee N.V., Bhattacharyya K., Bhattarai S., Bhutta Z.A., Biadgo B., Bikbov B., Briko A.N., Britton G., Burstein R., Butt Z.A., Car J., Castaneda-Orjuela C.A., Castro F., Cerin E., Chipeta M.G., Chu D.-T., Cork M.A., Cromwell E.A., Cuevas-Nasu L., Dandona L., Dandona R., Daoud F., Gupta R.D., Weaver N.D., Leo D.D., Neve J.-W.D., Deribe K., Desalegn B.B., Deshpande A., Desta M., Diaz D., Dinberu M.T., Doku D.T., Dubey M., Duraes A.R., Dwyer-Lindgren L., Earl L., Effiong A., Zaki M.E.S., Tantawi M.E., El-Khatib Z., Eshrati B., Fareed M., Faro A., Fereshtehnejad S.-M., Filip I., Fischer F., Foigt N.A., Folayan M.O., Fukumoto T., Gebrehiwot T.T., Gezae K.E., Ghajar A., Gill P.S., Gona P.N., Gopalani S.V., Grada A., Guo Y., Haj-Mirzaian A., Hall J.B., Hamidi S., Henok A., Prado B.H., Herrero M., Herteliu C., Hoang C.L., Hole M.K., Hossain N., Hosseinzadeh M., Hu G., Islam S.M.S., Jakovljevic M., Jha R.P., Jonas J.B., Jozwiak J.J., Kahsay A., Kanchan T., Karami M., Kasaeian A., Khader Y.S., Khan E.A., Khater M.M., Kim Y.J., Kimokoti R.W., Kisa A., Kochhar S., Kosen S., Koyanagi A., Krishan K., Defo B.K., Kumar G.A., Kumar M., Lad S.D., Lami F.H., Lee P.H., Levine A.J., Li S., Linn S., Lodha R., El Razek H.M.A., Abd El Razek M.M., Majdan M., Majeed A., Malekzadeh R., Malta D.C., Mamun A.A., Mansournia M.A., Martins-Melo F.R., Masaka A., Massenburg B.B., Mayala B.K., Mejia-Rodriguez F., Melku M., Mendoza W., Mensah G.A., Miazgowski T., Miller T.R., Mini G.K., Mirrakhimov E.M., Moazen B., Darwesh A.M., Mohammed S., Mohebi F., Mokdad A.H., Moodley Y., Moradi G., Moradi-Lakeh M., Moraga P., Morrison S.D., Mosser J.F., Mousavi S.M., Mueller U.O., Murray C.J.L., Mustafa G., Naderi M., Naghavi M., Najafi F., Nangia V., Ndwandwe D.E., Negoi I., Ngunjiri J.W., Nguyen H.L.T., Nguyen L.H., Nguyen S.H., Nie J., Nnaji C.A., Noubiap J.J., Shiadeh M.N., Nyasulu P.S., Ogbo F.A., Olagunju A.T., Olusanya B.O., Olusanya J.O., Ortiz-Panozo E., Otstavnov S.S., P. A M., Pana A., Pandey A., Pati S., Patil S.T., Patton G.C., Perico N., Pigott D.M., Pirsaheb M., Piwoz E.G., Postma M.J., Pourshams A., Prakash S., Quintana H., Radfar A., Rafiei A., Rahimi-Movaghar V., Rai R.K., Rajati F., Rawaf D.L., Rawaf S., Rawat R., Remuzzi G., Renzaho A.M.N., Rios-Gonzalez C., Roever L., Ross J.M., Rostami A., Sadat N., Safari Y., Safdarian M., Sahebkar A., Salam N., Salamati P., Salimi Y., Salimzadeh H., Samy A.M., Sartorius B., Sathian B., Schipp M.F., Schwebel D.C., Senbeta A.M., Sepanlou S.G., Shaikh M.A., Levy T.S., Shamsi M., Sharafi K., Sharma R., Sheikh A., Shil A., Silva D.A.S., Singh J.A., Sinha D.N., Soofi M., Sudaryanto A., Sufiyan M.B., Tabares-Seisdedos R., Tadesse B.T., Temsah M.-H., Terkawi A.S., Tessema Z.T., Thorne-Lyman A.L., Tovani-Palone M.R., Tran B.X., Tran K.B., Ullah I., Uthman O.A., Vaezghasemi M., Vaezi A., Valdez P.R., Vanderheide J., Veisani Y., Violante F.S., Vlassov V., Vu G.T., Vu L.G., Waheed Y., Walson J.L., Wang Y., Wang Y.-P., Wangia E.N., Werdecker A., Xu G., Yamada T., Yisma E., Yonemoto N., Younis M.Z., Yousefifard M., Yu C., Zaman S.B., Zamani M., Zhang Y., Kassebaum N.J., and Hay S.I.
Subjects: Time Factors, Developmental Disabilities, Psychological intervention, Distribution (economics), 0302 clinical medicine, risk factors, 030212 general & internal medicine, Signs and symptoms, Wasting, Children, Local Burden of Disease Child Growth Failure Collaborators, 2. Zero hunger, Multidisciplinary, Under-five, 1. No poverty, Public Health, Global Health, Social Medicine and Epidemiology, A900 Others in Medicine and Dentistry, 3. Good health, Multidisciplinary Sciences, Geography, Child, Preschool, Science & Technology - Other Topics, HEALTH, Underweight, medicine.symptom, social sciences, Infants, AFRICA, medicine.medical_specialty, General Science & Technology, RJ, Developing country, Nutritional Status, World Health Organization, Child Nutrition Disorders, Article, Social sciences, Malnutrició, 03 medical and health sciences, AGE, Environmental health, medicine, Mortalitat, Humans, Mortality, Developing Countries, Science & Technology, business.industry, Public health, MORTALITY, Body Weight, Malnutrition, Infant, Newborn, Infant, Child growth failure, medicine.disease, signs and symptoms, Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi, Risk factors, WEIGHT, business, RA, 030217 neurology & neurosurgery
Abstract: Childhood malnutrition is associated with high morbidity and mortality globally1. Undernourished children are more likely to experience cognitive, physical, and metabolic developmental impairments that can lead to later cardiovascular disease, reduced intellectual ability and school attainment, and reduced economic productivity in adulthood2. Child growth failure (CGF), expressed as stunting, wasting, and underweight in children under five years of age (0–59 months), is a specific subset of undernutrition characterized by insufficient height or weight against age-specific growth reference standards3–5. The prevalence of stunting, wasting, or underweight in children under five is the proportion of children with a height-for-age, weight-for-height, or weight-for-age z-score, respectively, that is more than two standard deviations below the World Health Organization’s median growth reference standards for a healthy population6. Subnational estimates of CGF report substantial heterogeneity within countries, but are available primarily at the first administrative level (for example, states or provinces)7; the uneven geographical distribution of CGF has motivated further calls for assessments that can match the local scale of many public health programmes8. Building from our previous work mapping CGF in Africa9, here we provide the first, to our knowledge, mapped high-spatial-resolution estimates of CGF indicators from 2000 to 2017 across 105 low- and middle-income countries (LMICs), where 99% of affected children live1, aggregated to policy-relevant first and second (for example, districts or counties) administrative-level units and national levels. Despite remarkable declines over the study period, many LMICs remain far from the ambitious World Health Organization Global Nutrition Targets to reduce stunting by 40% and wasting to less than 5% by 2025. Large disparities in prevalence and progress exist across and within countries; our maps identify high-prevalence areas even within nations otherwise succeeding in reducing overall CGF prevalence. By highlighting where the highest-need populations reside, these geospatial estimates can support policy-makers in planning interventions that are adapted locally and in efficiently directing resources towards reducing CGF and its health implications., High-resolution subnational mapping of child growth failure indicators for 105 low- and middle-income countries between 2000 and 2017 shows that, despite considerable progress, substantial geographical inequalities still exist in some countries.
Published: 2020

22. Global, regional, and national burden of traumatic brain injury and spinal cord injury, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

Author: James, Spencer L, Theadom, Alice, Ellenbogen, Richard G, Bannick, Marlena S, Mountjoy-Venning, W Cliff, Lucchesi, Lydia R, Abbasi, Nooshin, Abdulkader, Rizwan, Abraha, Haftom Niguse, Adsuar, Jose C, Afarideh, Mohsen, Agrawal, Sutapa, Ahmadi, Alireza, Ahmed, Muktar Beshir, Aichour, Amani Nidhal, Aichour, Ibtihel, Aichour, Miloud Taki Eddine, Akinyemi, Rufus Olusola, Akseer, Nadia, Alahdab, Fares, Alebel, Animut, Alghnam, Suliman A, Ali, Beriwan Abdulqadir, Alsharif, Ubai, Altirkawi, Khalid, Andrei, Catalina Liliana, Anjomshoa, Mina, Ansari, Hossein, Ansha, Mustafa Geleto, Antonio, Carl Abelardo T, Appiah, Seth Christopher Yaw, Ariani, Filippo, Asefa, Nigus Gebremedhin, Asgedom, Solomon Weldegebreal, Atique, Suleman, Awasthi, Ashish, Quintanilla, Beatriz Paulina Ayala, Ayuk, Tambe B, Azzopardi, Peter S, Badali, Hamid, Badawi, Alaa, Balalla, Shivanthi, Banstola, Amrit, Barker-Collo, Suzanne Lyn, Barnighausen, Till Winfried, Bedi, Neeraj, Behzadifar, Masoud, Behzadifar, Meysam, Bekele, Bayu Begashaw, Belachew, Abate Bekele, Belay, Yihalem Abebe, Bennett, Derrick A, Bensenor, Isabela M, Berhane, Adugnaw, Beuran, Mircea, Bhalla, Ashish, Bhaumik, Soumyadeeep, Bhutta, Zulfiqar A, Biadgo, Belete, Biffino, Marco, Bijani, Ali, Bililign, Nigus, Birungi, Charles, Boufous, Soufiane, Brazinova, Alexandra, Brown, Allen W, Car, Mate, Cardenas, Rosario, Carrero, Juan J, Carvalho, Felix, Castaneda-Orjuela, Carlos A, Catala-Lopez, Ferran, Chaiah, Yazan, Champs, Ana Paula, Chang, Jung-Chen, Choi, Jee-Young J, Christopher, Devasahayam J, Cooper, Cyrus, Crowe, Christopher Stephen, Dandona, Lalit, Dandona, Rakhi, Daryani, Ahmad, Davitoiu, Dragos Virgil, Degefa, Meaza Girma, Demoz, Gebre Teklemariam, Deribe, Kebede, Djalalinia, Shirin, Do, Huyen Phuc, Doku, David Teye, Drake, Thomas M, Dubey, Manisha, Dubljanin, Eleonora, El-Khatib, Ziad, Eskandarieh, Sharareh, Esteghamati, Alireza, Esteghamati, Sadaf, Faro, Andre, Farzadfar, Farshad, Farzaei, Mohammad Hosein, Fereshtehnejad, Seyed-Mohammad, Fernandes, Eduarda, Feyissa, Garumma Tolu, Filip, Irina, Fischer, Florian, Fukumoto, Takeshi, Ganji, Morasaleh, Gankpe, Fortune Gbetoho, Gebre, Abadi Kahsu, Gebrehiwot, Tsegaye Tewelde, Gezae, Kebede Embaye, Gopalkrishna, Gururaj, Goulart, Alessandra C, Haagsma, Juanita A, Haj-Mirzaian, Arvin, Haj-Mirzaian, Arya, Hamadeh, Randah R, Hamidi, Samer, Haro, Josep Maria, Hassankhani, Hadi, Hassen, Hamid Yimam, Havmoeller, Rasmus, Hawley, Caitlin, Hay, Simon I, Hegazy, Mohamed I, Hendrie, Delia, Henok, Andualem, Hibstu, Desalegn Tsegaw, Hoffman, Howard J, Hole, Michael K, Rad, Enayatollah Homaie, Hosseini, Seyed Mostafa, Hostiuc, Sorin, Hu, Guoqing, Hussen, Mamusha Aman, Ilesanmi, Olayinka Stephen, Irvani, Seyed Naghibi, Jakovljevic, Mihajlo, Jayaraman, Sudha, Jha, Ravi Prakash, Jonas, Jost B, Jones, Kelly M, Shushtari, Zahra Jorjoran, Jozwiak, Jacek Jerzy, Jurisson, Mikk, Kabir, Ali, Kahsay, Amaha, Kahssay, Molla, Kalani, Rizwan, Karch, Andre, Kasaeian, Amir, Kassa, Getachew 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Tomislav, Miazgowski, Tomasz, Miller, Ted R, Mini, GK, Mirica, Andreea, Mirrakhimov, Erkin M, Moazen, Babak, Mohammadi, Moslem, Mokdad, Ali H, Molokhia, Mariam, Monasta, Lorenzo, Mondello, Stefania, Moosazadeh, Mahmood, Moradi, Ghobad, Moradi, Mahmoudreza, Moradi-Lakeh, Maziar, Moradinazar, Mehdi, Morrison, Shane Douglas, Moschos, Marilita M, Mousavi, Seyyed Meysam, Murthy, Srinivas, Musa, Kamarul Imran, Mustafa, Ghulam, Naghavi, Mohsen, Naik, Gurudatta, Najafi, Farid, Nangia, Vinay, Nascimento, Bruno Ramos, Negoi, Ionut, Nguyen, Trang Huyen, Nichols, Emma, Ningrum, Dina Nur Anggraini, Nirayo, Yirga Legesse, Nyasulu, Peter S, Ofori-Asenso, Richard, Ogbo, Felix Akpojene, Oh, In-Hwan, Okoro, Anselm, Olagunju, Andrew T, Olagunju, Tinuke O, Olivares, Pedro R, Otstavnov, Stanislav S, Owolabi, Mayowa Ojo, Mahesh, PA, Pakhale, Smita, Pandey, Achyut Raj, Pesudovs, Konrad, Pinilla-Monsalve, Gabriel D, Polinder, Suzanne, Poustchi, Hossein, Prakash, Swayam, Qorbani, Mostafa, Radfar, Amir, Rafay, Anwar, Rafiei, Alireza, Rahimi-Movaghar, Afarin, Rahimi-Movaghar, Vafa, Rahman, Mahfuzar, Rahman, Muhammad Aziz, Rai, Rajesh Kumar, Rajati, Fatemeh, Ram, Usha, Rawaf, David Laith, Rawaf, Salman, Reiner, Robert C, Reis, Cesar, Renzaho, Andre MN, Resnikoff, Serge, Rezaei, Satar, Rezaeian, Shahab, Roever, Leonardo, Ronfani, Luca, Roshandel, Gholamreza, Roy, Nobhojit, Ruhago, George Mugambage, Saddik, Basema, Safari, Hosein, Safiri, Saeid, Sahraian, Mohammad Ali, Salamati, Payman, Saldanha, Raphael de Freitas, Samy, Abdallah M, Sanabria, Juan, Santos, Joao Vasco, Milicevic, Milena MM Santric, Sartorius, Benn, Satpathy, Maheswar, Schneider, Ione JC, Schwebel, David C, Sepanlou, Sadaf G, Shabaninejad, Hosein, Shaikh, Masood A Ali, Shams-Beyranvand, Mehran, Sharif, Mehdi, Sharif-Alhoseini, Mahdi, Islam, Sheikh Mohammed Shariful, She, Jun, Sheikh, Aziz, Shen, Jiabin, Sheth, Kevin N, Shibuya, Kenji, Shiferaw, Mekonnen Sisay, Shigematsu, Mika, Shiri, Rahman, Shiue, Ivy, Shoman, Haitham, Siabani, Soraya, Siddiqi, Tariq J, Silva, Joao Pedro, Silveira, Dayane Gabriele Alves, Sinha, Dhirendra Narain, Smith, Mari, Soares Filho, Adauto Martins, Sobhani, Soheila, Soofi, Moslem, Soriano, Joan B, Soyiri, Ireneous N, Stein, Dan J, Stokes, Mark A, Sufiyan, Mu'awiyyah Babale, Sunguya, Bruno F, Sunshine, Jacob E, Sykes, Bryan L, Szoeke, Cassandra EI, Tabares-Seisdedos, Rafael, Ao, Braden James Te, Tehrani-Banihashemi, Arash, Tekle, Merhawi Gebremedhin, Temsah, Mohamad-Hani, Temsah, Omar, Topor-Madry, Roman, Tortajada-Girbes, Miguel, Tran, Bach Xuan, Tran, Khanh Bao, Car, Lorainne Tudor, Ukwaja, Kingsley Nnanna, Ullah, Irfan, Usman, Muhammad Shariq, Uthman, Olalekan A, Valdez, Pascual R, Vasankari, Tommi Juhani, Venketasubramanian, Narayanaswamy, Violante, Francesco S, Wagnew, Fasil Shiferaw, Waheed, Yasir, Wang, Yuan-Pang, Weldegwergs, Kidu Gidey, Werdecker, Andrea, Wijeratne, Tissa, Winkler, Andrea Sylvia, Wyper, Grant MA, Yano, Yuichiro, Yaseri, Mehdi, Yasin, Yasin Jemal, Ye, Pengpeng, Yimer, Ebrahim M, Yip, Paul, Yisma, Engida, Yonemoto, Naohiro, Yoon, Seok-Jun, Yost, Michael G, Younis, Mustafa Z, Yousefifard, Mahmoud, Yu, Chuanhua, Zaidi, Zoubida, Bin Zaman, Sojib, Zamani, Mohammad, Zenebe, Zerihun Menlkalew, Zodpey, Sanjay, Feigin, Valery L, Vos, Theo, Murray, Christopher JL, Sp, GBD 2016 Traumatic Brain Injury, James S.L., Theadom A., Ellenbogen R.G., Bannick M.S., Montjoy-Venning W., Lucchesi L.R., Abbasi N., Abdulkader R., Abraha H.N., Adsuar J.C., Afarideh M., Agrawal S., Ahmadi A., Ahmed M.B., Aichour A.N., Aichour I., Aichour M.T.E., Akinyemi R.O., Akseer N., Alahdab F., Alebel A., Alghnam S.A., Ali B.A., Alsharif U., Altirkawi K., Andrei C.L., Anjomshoa M., Ansari H., Ansha M.G., Antonio C.A.T., Appiah S.C.Y., Ariani F., Asefa N.G., Asgedom S.W., Atique S., Awasthi A., Ayala Quintanilla B.P., Ayuk T.B., Azzopardi P.S., Badali H., Badawi A., Balalla S., Banstola A., Barker-Collo S.L., Barnighausen T.W., Bedi N., Behzadifar M., Bekele B.B., Belachew A.B., Belay Y.A., Bennett D.A., Bensenor I.M., Berhane A., Beuran M., Bhalla A., Bhaumik S., Bhutta Z.A., Biadgo B., Biffino M., Bijani A., Bililign N., Birungi C., Boufous S., Brazinova A., Brown A.W., Car M., Cardenas R., Carrero J.J., Carvalho F., Castaneda-Orjuela C.A., Catala-Lopez F., Chaiah Y., Champs A.P., Chang J.-C., Choi J.-Y.J., Christopher D.J., Cooper C., Crowe C.S., Dandona L., Dandona R., Daryani A., Davitoiu D.V., Degefa M.G., Demoz G.T., Deribe K., Djalalinia S., Do H.P., Doku D.T., Drake T.M., Dubey M., Dubljanin E., El-Khatib Z., Ofori-Asenso R., Eskandarieh S., Esteghamati A., Esteghamati S., Faro A., Farzadfar F., Farzaei M.H., Fereshtehnejad S.-M., Fernandes E., Feyissa G.T., Filip I., Fischer F., Fukumoto T., Ganji M., Gankpe F.G., Gebre A.K., Gebrehiwot T.T., Gezae K.E., Gopalkrishna G., Goulart A.C., Haagsma J.A., Haj-Mirzaian A., Hamadeh R.R., Hamidi S., Haro J.M., Hassankhani H., Hassen H.Y., Havmoeller R., Hawley C., Hay S.I., Hegazy M.I., Hendrie D., Henok A., Hibstu D.T., Hoffman H.J., Hole M.K., Homaie Rad E., Hosseini S.M., Hostiuc S., Hu G., Hussen M.A., Ilesanmi O.S., Irvani S.S.N., Jakovljevic M., Jayaraman S., Jha R.P., Jonas J.B., Jones K.M., Jorjoran Shushtari Z., Jozwiak J.J., Jurisson M., Kabir A., Kahsay A., Kahssay M., Kalani R., Karch A., Kasaeian A., Kassa G.M., Kassa T.D., Kassa Z.Y., Kengne A.P., Khader Y.S., Khafaie M.A., Khalid N., Khalil I., Khan E.A., Khan M.S., Khang Y.-H., Khazaie H., Khoja A.T., Khubchandani J., Kiadaliri A.A., Kim D., Kim Y.-E., Kisa A., Koyanagi A., Krohn K.J., Kuate Defo B., Kucuk Bicer B., Kumar G.A., Kumar M., Lalloo R., Lami F.H., Lansingh V.C., Laryea D.O., Latifi A., Leshargie C.T., Levi M., Li S., Liben M.L., Lotufo P.A., Lunevicius R., Mahotra N.B., Majdan M., Majeed A., Malekzadeh R., Manda A.-L., Mansournia M.A., Massenburg B.B., Mate K.K.V., Mehndiratta M.M., Mehta V., Meles H., Melese A., Memiah P.T.N., Mendoza W., Mengistu G., Meretoja A., Meretoja T.J., Mestrovic T., Miazgowski T., Miller T.R., Mini G.K., Mirica A., Mirrakhimov E.M., Moazen B., Mohammadi M., Molokhia M., Monasta L., Mondello S., Moosazadeh M., Moradi G., Moradi M., Moradi-Lakeh M., Moradinazar M., Morrison S.D., Moschos M.M., Mousavi S.M., Murthy S., Musa K.I., Mustafa G., Naghavi M., Naik G., Najafi F., Nangia V., Nascimento B.R., Negoi I., Nguyen T.H., Nichols E., Ningrum D.N.A., Nirayo Y.L., Nyasulu P.S., Ogbo F.A., Oh I.-H., Okoro A., Olagunju A.T., Olagunju T.O., Olivares P.R., Otstavnov S.S., Owolabi M.O., P A M., Pakhale S., Pandey A.R., Pesudovs K., Pinilla-Monsalve G.D., Polinder S., Poustchi H., Prakash S., Qorbani M., Radfar A., Rafay A., Rafiei A., Rahimi-Movaghar A., Rahimi-Movaghar V., Rahman M., Rahman M.A., Rai R.K., Rajati F., Ram U., Rawaf D.L., Rawaf S., Reiner R.C., Reis C., Renzaho A.M.N., Resnikoff S., Rezaei S., Rezaeian S., Roever L., Ronfani L., Roshandel G., Roy N., Ruhago G.M., Saddik B., Safari H., Safiri S., Sahraian M.A., Salamati P., Saldanha R.D.F., Samy A.M., Sanabria J., Santos J.V., Santric Milicevic M.M.M., Sartorius B., Satpathy M., Savuon K., Schneider I.J.C., Schwebel D.C., Sepanlou S.G., Shabaninejad H., Shaikh M.A.A., Shams-Beyranvand M., Sharif M., Sharif-Alhoseini M., Shariful Islam S.M., She J., Sheikh A., Shen J., Sheth K.N., Shibuya K., Shiferaw M.S., Shigematsu M., Shiri R., Shiue I., Shoman H., Siabani S., Siddiqi T.J., Silva J.P., Silveira D.G.A., Sinha D.N., Smith M., Soares Filho A.M., Sobhani S., Soofi M., Soriano J.B., Soyiri I.N., Stein D.J., Stokes M.A., Sufiyan M.B., Sunguya B.F., Sunshine J.E., Sykes B.L., Szoeke C.E.I., Tabares-Seisdedos R., Te Ao B.J., Tehrani-Banihashemi A., Tekle M.G., Temsah M.-H., Temsah O., Topor-Madry R., Tortajada-Girbes M., Tran B.X., Tran K.B., Tudor Car L., Ukwaja K.N., Ullah I., Usman M.S., Uthman O.A., Valdez P.R., Vasankari T.J., Venketasubramanian N., Violante F.S., Wagnew F.W.S., Waheed Y., Wang Y.-P., Weldegwergs K.G., Werdecker A., Wijeratne T., Winkler A.S., Wyper G.M.A., Yano Y., Yaseri M., Yasin Y.J., Ye P., Yimer E.M., Yip P., Yisma E., Yonemoto N., Yoon S.-J., Yost M.G., Younis M.Z., Yousefifard M., Yu C., Zaidi Z., Zaman S.B., Zamani M., Zenebe Z.M., Zodpey S., Feigin V.L., Vos T., Murray C.J.L., and Bill & Melinda Gates Foundation
Subjects: Science & Technology, Neurology & Neurosurgery, NEW-ZEALAND, Clinical Neurology, UNITED-STATES, 1103 Clinical Sciences, Epidemology, spinal cord injury, Global Burden of Disease, Traumatic brain injury, United-States, New-Zealand, Epidemology, Survival, GBD 2016 Traumatic Brain Injury and Spinal Cord Injury Collaborators, Brain Injuries, Traumatic, SURVIVAL, brain injury, spinal cord injury, EPIDEMIOLOGY, Global Burden Disease, Neurosciences & Neurology, 1109 Neurosciences, Life Sciences & Biomedicine, Spinal Cord Injuries
Abstract: BACKGROUND: Traumatic brain injury (TBI) and spinal cord injury (SCI) are increasingly recognised as global health priorities in view of the preventability of most injuries and the complex and expensive medical care they necessitate. We aimed to measure the incidence, prevalence, and years of life lived with disability (YLDs) for TBI and SCI from all causes of injury in every country, to describe how these measures have changed between 1990 and 2016, and to estimate the proportion of TBI and SCI cases caused by different types of injury. METHODS: We used results from the Global Burden of Diseases, Injuries, and Risk Factors (GBD) Study 2016 to measure the global, regional, and national burden of TBI and SCI by age and sex. We measured the incidence and prevalence of all causes of injury requiring medical care in inpatient and outpatient records, literature studies, and survey data. By use of clinical record data, we estimated the proportion of each cause of injury that required medical care that would result in TBI or SCI being considered as the nature of injury. We used literature studies to establish standardised mortality ratios and applied differential equations to convert incidence to prevalence of long-term disability. Finally, we applied GBD disability weights to calculate YLDs. We used a Bayesian meta-regression tool for epidemiological modelling, used cause-specific mortality rates for non-fatal estimation, and adjusted our results for disability experienced with comorbid conditions. We also analysed results on the basis of the Socio-demographic Index, a compound measure of income per capita, education, and fertility. FINDINGS: In 2016, there were 27·08 million (95% uncertainty interval [UI] 24·30-30·30 million) new cases of TBI and 0·93 million (0·78-1·16 million) new cases of SCI, with age-standardised incidence rates of 369 (331-412) per 100 000 population for TBI and 13 (11-16) per 100 000 for SCI. In 2016, the number of prevalent cases of TBI was 55·50 million (53·40-57·62 million) and of SCI was 27·04 million (24·98-30·15 million). From 1990 to 2016, the age-standardised prevalence of TBI increased by 8·4% (95% UI 7·7 to 9·2), whereas that of SCI did not change significantly (-0·2% [-2·1 to 2·7]). Age-standardised incidence rates increased by 3·6% (1·8 to 5·5) for TBI, but did not change significantly for SCI (-3·6% [-7·4 to 4·0]). TBI caused 8·1 million (95% UI 6·0-10·4 million) YLDs and SCI caused 9·5 million (6·7-12·4 million) YLDs in 2016, corresponding to age-standardised rates of 111 (82-141) per 100 000 for TBI and 130 (90-170) per 100 000 for SCI. Falls and road injuries were the leading causes of new cases of TBI and SCI in most regions. INTERPRETATION: TBI and SCI constitute a considerable portion of the global injury burden and are caused primarily by falls and road injuries. The increase in incidence of TBI over time might continue in view of increases in population density, population ageing, and increasing use of motor vehicles, motorcycles, and bicycles. The number of individuals living with SCI is expected to increase in view of population growth, which is concerning because of the specialised care that people with SCI can require. Our study was limited by data sparsity in some regions, and it will be important to invest greater resources in collection of data for TBI and SCI to improve the accuracy of future assessments. FUNDING: Bill & Melinda Gates Foundation. Bill & Melinda Gates Foundation We acknowledge the funding and support of the Bill & Melinda Gates Foundation. AK was supported by the Miguel Servet contract, which was financed by the CP13/00150 and PI15/00862 projects integrated into the National Research, Development, and Implementation,and funded by the Instituto de Salud Carlos III General Branch Evaluation and Promotion of Health Research and the European Regional Development Fund (ERDF-FEDER). AMS is supported by the Egyptian Fulbright Mission Program. AF acknowledges the Federal University of Sergipe (Sergipe, Brazil). AA received financial assistance from the Indian Department of Science and Technology (New Delhi, India) through the INSPIRE faculty programme. AS is supported by Health Data Research UK. DJS is supported by the South African Medical Research Council. AB is supported by the Public Health Agency of Canada. SMSI received a senior research fellowship from the Institute for Physical Activity and Nutrition, Deakin University (Waurn Ponds, VIC, Australia), and a career transition grant from the High Blood Pressure Research Council of Australia. FP and CF acknowledge support from the European Union (FEDER funds POCI/01/0145/FEDER/007728 and POCI/01/0145/FEDER/007265) and National Funds (FCT/MEC, Fundação para a Ciência e a Tecnologia, and Ministério da Educação e Ciência) under the Partnership Agreements PT2020 UID/MULTI/04378/2013 and PT2020 UID/QUI/50006/2013. TB acknowledges financial support from the Institute of Medical Research and Medicinal Plant Studies, Yaoundé, Cameroon. AM of Imperial College London is grateful for support from the Northwest London National Institute for Health Research (NIHR) Collaboration for Leadership in Applied Health Research andCare and the Imperial NIHR Biomedical Research Centre. KD is funded by a Wellcome Trust Intermediate Fellowship in Public Health and Tropical Medicine (grant number 201900). PSA is supported by an Australian National Health and Medical Research Council Early Career Fellowship. RT-S was supported in part by grant number PROMETEOII/2015/021 from Generalitat Valenciana and the national grant PI17/00719 from ISCIII-FEDER. The Serbian part of this contribution (by MJ) has been co-financed with grant OI175014 from the Serbian Ministry of Education, Science and Technological Development; publication of results was not contingent upon the Ministry’s approval. MMMSM acknowledges support from the Serbian Ministry of Education, Science and Technological Development (contract 175087). MM’s research was supported by the NIHR Biomedical Research Centre at Guy’s and St Thomas’ NHS Foundation Trust (London, UK) and King’s College London. The views expressed are those of the authors and not necessarily those of the UK National Health Service, the NIHR, or the UK Department of Health. TWB was supported by the Alexander von Humboldt Foundation through the Alexander von Humboldt professor award, which was funded by the German Federal Ministry of Education and Research Sí
Published: 2019

23. Carga global, regional y nacional de neurológicas. Desórdenes, 1990-2016: un análisis sistemático para el Global Estudio de la carga de enfermedad 2016

Author: Feigin V, Nichols E, Alam T, Bannick M, Beghi E, Blake N, Culpepper W, Dorsey E, Elbaz A, Ellenbogen R, Fisher J, Fitzmaurice C, Giussani G, Glennie L, James S, Johnson C, Kassebaum N, Logroscino G, Marin B, Mountjoy-Venning W, Nguyen M, Ofori-Asenso R, Patel A, Piccininni M, Roth G, Steiner T, Stovner L, Szoeke C, Theadom A, Vollset S, Wallin M, Wright C, Zunt J, Abbasi N, Abd-Allah F, Abdelalim A, Abdollahpour I, Aboyans V, Abraha H, Acharya D, Adamu A, Adebayo O, Adeoye A, Adsuar J, Afarideh M, Agrawal S, Ahmadi A, Ahmed M, Aichour A, Aichour I, Aichour M, Akinyemi R, Akseer N, Al-Eyadhy A, Salman R, Alahdab F, Alene K, Aljunid S, Altirkawi K, Alvis-Guzman N, Anber N, Antonio C, Arabloo J, Aremu O, Arnlov J, Asayesh H, Asghar R, Atalay H, Awasthi A, Quintanilla B, Ayuk T, Badawi A, Banach M, Banoub J, Barboza M, Barker-Collo S, Barnighausen T, Baune B, Bedi N, Behzadifar M, Bejot Y, Bekele B, Belachew A, Bennett D, Bensenor I, Berhane A, Beuran M, Bhattacharyya K, Bhutta Z, Biadgo B, Bijani A, Bililign N, Bin Sayeed M, Blazes C, Brayne C, Butt Z, Campos-Nonato I, Cantu-Brito C, Car M, Cardenas R, Carrero J, Carvalho F, Castaneda-Orjuela C, Castro F, Catala-Lopez F, Cerin E, Chaiah Y, Chang J, Chatziralli I, Chiang P, Christensen H, Christopher D, Cooper C, Cortesi P, Costa V, Criqui M, Crowe C, Damasceno A, Daryani A, De la Cruz-Gongora V, De la Hoz F, De Leo D, Degefa M, Demoz G, Deribe K, Dharmaratne S, Diaz D, Dinberu M, Djalalinia S, Doku D, Dubey M, Dubljanin E, Duken E, Edvardsson D, El-Khatib Z, Endres M, Endries A, Eskandarieh S, Esteghamati A, Esteghamati S, Farhadi F, Faro A, Farzadfar F, Farzaei M, Fatima B, Fereshtehnejad S, Fernandes E, Feyissa G, Filip I, Fischer F, Fukumoto T, Ganji M, Gankpe F, Garcia-Gordillo M, Gebre A, Gebremichael T, Gelaw B, Geleijnse J, Geremew D, Gezae K, Ghasemi-Kasman M, Gidey M, Gill P, Gill T, Gnedovskaya E, Goulart A, Grada A, Grosso G, Guo Y, Gupta R, Haagsma J, Hagos T, Haj-Mirzaian A, Hamadeh R, Hamidi S, Hankey G, Hao Y, Haro J, Hassankhani H, Hassen H, Havmoeller R, Hay S, Hegazy M, Heidari B, Henok A, Heydarpour F, Hoang C, Hole M, Rad E, Hosseini S, Hu G, Igumbor E, Ilesanmi O, Irvani S, Islam S, Jakovljevic M, Javanbakht M, Jha R, Jobanputra Y, Jonas J, Jozwiak J, Jurisson M, Kahsay A, Kalani R, Kalkonde Y, Kamil T, Kanchan T, Karami M, Karch A, Karimi N, Kasaeian A, Kassa T, Kassa Z, Kaul A, Kefale A, Keiyoro P, Khader Y, Khafaie M, Khalil I, Khan E, Khang Y, Khazaie H, Kiadaliri A, Kiirithio D, Kim A, Kim D, Kim Y, Kisa A, Kokubo Y, Koyanagi A, Krishnamurthi R, Defo B, Bicer B, Kumar M, Lacey B, Lafranconi A, Lansingh V, Latifi A, Leshargie C, Li S, Liao Y, Linn S, Lo W, Lopez J, Lorkowski S, Lotufo P, Lucas R, Lunevicius R, Mackay M, Mahotra N, Majdan M, Majdzadeh R, Majeed A, Malekzadeh R, Malta D, Manafi N, Mansournia M, Mantovani L, Marz W, Mashamba-Thompson T, Massenburg B, Mate K, McAlinden C, McGrath J, Mehta V, Meier T, Meles H, Melese A, Memiah P, Memish Z, Mendoza W, Mengistu D, Mengistu G, Meretoja A, Meretoja T, Mestrovic T, Miazgowski B, Miazgowski T, Miller T, Mini G, Mirrakhimov E, Moazen B, Mohajer B, Mezerji N, Mohammadi M, Mohammadi-Khanaposhtani M, Mohammadibakhsh R, Mohammadnia-Afrouzi M, Mohammed S, Mohebi F, Mokdad A, Monasta L, Mondello S, Moodley Y, Moosazadeh M, Moradi G, Moradi-Lakeh M, Moradinazar M, Moraga P, Velasquez I, Morrison S, Mousavi S, Muhammed O, Muruet W, Musa K, Mustafa G, Naderi M, Nagel G, Naheed A, Naik G, Najafi F, Nangia V, Negoi I, Negoi R, Newton C, Ngunjiri J, Nguyen C, Nguyen L, Ningrum D, Nirayo Y, Nixon M, Norrving B, Noubiap J, Shiadeh M, Nyasulu P, Ogbo F, Oh I, Olagunju A, Olagunju T, Olivares P, Onwujekwe O, Oren E, Owolabi M, Mahesh P, Pakpour A, Pan W, Panda-Jonas S, Pandian J, Patel S, Pereira D, Petzold M, Pillay J, Piradov M, Polanczyk G, Polinder S, Postma M, Poulton R, Poustchi H, Prakash S, Prakash V, Qorbani M, Radfar A, Rafay A, Rafiei A, Rahim F, Rahimi-Movaghar V, Rahman M, Rajati F, Ram U, Ranta A, Rawaf D, Rawaf S, Reinig N, Reis C, Renzaho A, Resnikoff S, Rezaeian S, Rezai M, Gonzalez C, Roberts N, Roever L, Ronfani L, Roro E, Roshandel G, Rostami A, Sabbagh P, Sacco R, Sachdev P, Saddik B, Safari H, Safari-Faramani R, Safi S, Safiri S, Sagar R, Sahathevan R, Sahebkar A, Sahraian M, Salamati P, Zahabi S, Salimi Y, Samy A, Sanabria J, Santos I, Milicevic M, Sarrafzadegan N, Sartorius B, Sarvi S, Sathian B, Satpathy M, Sawant A, Sawhney M, Schneider I, Schottker B, Schwebel D, Seedat S, Sepanlou S, Shabaninejad H, Shafieesabet A, Shaikh M, Shakir R, Shams-Beyranvand M, Shamsizadeh M, Sharif M, Sharif-Alhoseini M, She J, Sheikh A, Sheth K, Shigematsu M, Shiri R, Shirkoohi R, Shiue I, Siabani S, Siddiqi T, Sigfusdottir I, Sigurvinsdottir R, Silberberg D, Silva J, Silveira D, Singh J, Sinha D, Skiadaresi E, Smith M, Sobaih B, Sobhani S, Soofi M, Soyiri I, Sposato L, Stein D, Stein M, Stokes M, Sufiyan M, Sykes B, Sylaja P, Tabares-Seisdedos R, Ao B, Tehrani-Banihashemi A, Temsah M, Temsah O, Thakur J, Thrift A, Topor-Madry R, Tortajada-Girbes M, Tovani-Palone M, Tran B, Tran K, Truelsen T, Tsadik A, Car L, Ukwaja K, Ullah I, Usman M, Uthman O, Valdez P, Vasankari T, Vasanthan R, Veisani Y, Venketasubramanian N, Violante F, Vlassov V, Vosoughi K, Vu G, Vujcic I, Wagnew F, Waheed Y, Wang Y, Weiderpass E, Weiss J, Whiteford H, Wijeratne T, Winkler A, Wiysonge C, Wolfe C, Xu G, Yadollahpour A, Yamada T, Yano Y, Yaseri M, Yatsuya H, Yimer E, Yip P, Yisma E, Yonemoto N, Yousefifard M, Yu C, Zaidi Z, Bin Zaman S, Zamani M, Zandian H, Zare Z, Zhang Y, Zodpey S, Naghavi M, Murray C, Vos T, GBD 2016 Neurology Collaborators, Bill & Melinda Gates Foundation, VU University medical center, Feigin V.L., Nichols E., Alam T., Bannick M.S., Beghi E., Blake N., Culpepper W.J., Dorsey E.R., Elbaz A., Ellenbogen R.G., Fisher J.L., Fitzmaurice C., Giussani G., Glennie L., James S.L., Johnson C.O., Kassebaum N.J., Logroscino G., Marin B., Mountjoy-Venning W.C., Nguyen M., Ofori-Asenso R., Patel A.P., Piccininni M., Roth G.A., Steiner T.J., Stovner L.J., Szoeke C.E.I., Theadom A., Vollset S.E., Wallin M.T., Wright C., Zunt J.R., Abbasi N., Abd-Allah F., Abdelalim A., Abdollahpour I., Aboyans V., Abraha H.N., Acharya D., Adamu A.A., Adebayo O.M., Adeoye A.M., Adsuar J.C., Afarideh M., Agrawal S., Ahmadi A., Ahmed M.B., Aichour A.N., Aichour I., Aichour M.T.E., Akinyemi R.O., Akseer N., Al-Eyadhy A., Al-Shahi Salman R., Alahdab F., Alene K.A., Aljunid S.M., Altirkawi K., Alvis-Guzman N., Anber N.H., Antonio C.A.T., Arabloo J., Aremu O., Arnlov J., Asayesh H., Asghar R.J., Atalay H.T., Awasthi A., Ayala Quintanilla B.P., Ayuk T.B., Badawi A., Banach M., Banoub J.A.M., Barboza M.A., Barker-Collo S.L., Barnighausen T.W., Baune B.T., Bedi N., Behzadifar M., Bejot Y., Bekele B.B., Belachew A.B., Bennett D.A., Bensenor I.M., Berhane A., Beuran M., Bhattacharyya K., Bhutta Z.A., Biadgo B., Bijani A., Bililign N., Bin Sayeed M.S., Blazes C.K., Brayne C., Butt Z.A., Campos-Nonato I.R., Cantu-Brito C., Car M., Cardenas R., Carrero J.J., Carvalho F., Castaneda-Orjuela C.A., Castro F., Catala-Lopez F., Cerin E., Chaiah Y., Chang J.-C., Chatziralli I., Chiang P.P.-C., Christensen H., Christopher D.J., Cooper C., Cortesi P.A., Costa V.M., Criqui M.H., Crowe C.S., Damasceno A.A.M., Daryani A., De la Cruz-Gongora V., De La Hoz F.P., De Leo D., Degefa M.G., Demoz G.T., Deribe K., Dharmaratne S.D., Diaz D., Dinberu M.T., Djalalinia S., Doku D.T., Dubey M., Dubljanin E., Duken E.E., Edvardsson D., El-Khatib Z., Endres M., Endries A.Y., Eskandarieh S., Esteghamati A., Esteghamati S., Farhadi F., Faro A., Farzadfar F., Farzaei M.H., Fatima B., Fereshtehnejad S.-M., Fernandes E., Feyissa G.T., Filip I., Fischer F., Fukumoto T., Ganji M., Gankpe F.G., Garcia-Gordillo M.A., Gebre A.K., Gebremichael T.G., Gelaw B.K., Geleijnse J.M., Geremew D., Gezae K.E., Ghasemi-Kasman M., Gidey M.Y., Gill P.S., Gill T.K., Gnedovskaya E.V., Goulart A.C., Grada A., Grosso G., Guo Y., Gupta R., Haagsma J.A., Hagos T.B., Haj-Mirzaian A., Hamadeh R.R., Hamidi S., Hankey G.J., Hao Y., Haro J.M., Hassankhani H., Hassen H.Y., Havmoeller R., Hay S.I., Hegazy M.I., Heidari B., Henok A., Heydarpour F., Hoang C.L., Hole M.K., Homaie Rad E., Hosseini S.M., Hu G., Igumbor E.U., Ilesanmi O.S., Irvani S.S.N., Islam S.M.S., Jakovljevic M., Javanbakht M., Jha R.P., Jobanputra Y.B., Jonas J.B., Jozwiak J.J., Jurisson M., Kahsay A., Kalani R., Kalkonde Y., Kamil T.A., Kanchan T., Karami M., Karch A., Karimi N., Kasaeian A., Kassa T.D., Kassa Z.Y., Kaul A., Kefale A.T., Keiyoro P.N., Khader Y.S., Khafaie M.A., Khalil I.A., Khan E.A., Khang Y.-H., Khazaie H., Kiadaliri A.A., Kiirithio D.N., Kim A.S., Kim D., Kim Y.-E., Kim Y.J., Kisa A., Kokubo Y., Koyanagi A., Krishnamurthi R.V., Kuate Defo B., Kucuk Bicer B., Kumar M., Lacey B., Lafranconi A., Lansingh V.C., Latifi A., Leshargie C.T., Li S., Liao Y., Linn S., Lo W.D., Lopez J.C.F., Lorkowski S., Lotufo P.A., Lucas R.M., Lunevicius R., Mackay M.T., Mahotra N.B., Majdan M., Majdzadeh R., Majeed A., Malekzadeh R., Malta D.C., Manafi N., Mansournia M.A., Mantovani L.G., Marz W., Mashamba-Thompson T.P., Massenburg B.B., Mate K.K.V., McAlinden C., McGrath J.J., Mehta V., Meier T., Meles H.G., Melese A., Memiah P.T.N., Memish Z.A., Mendoza W., Mengistu D.T., Mengistu G., Meretoja A., Meretoja T.J., Mestrovic T., Miazgowski B., Miazgowski T., Miller T.R., Mini G.K., Mirrakhimov E.M., Moazen B., Mohajer B., Mohammad Gholi Mezerji N., Mohammadi M., Mohammadi-Khanaposhtani M., Mohammadibakhsh R., Mohammadnia-Afrouzi M., Mohammed S., Mohebi F., Mokdad A.H., Monasta L., Mondello S., Moodley Y., Moosazadeh M., Moradi G., Moradi-Lakeh M., Moradinazar M., Moraga P., Moreno Velasquez I., Morrison S.D., Mousavi S.M., Muhammed O.S., Muruet W., Musa K.I., Mustafa G., Naderi M., Nagel G., Naheed A., Naik G., Najafi F., Nangia V., Negoi I., Negoi R.I., Newton C.R.J., Ngunjiri J.W., Nguyen C.T., Nguyen L.H., Ningrum D.N.A., Nirayo Y.L., Nixon M.R., Norrving B., Noubiap J.J., Nourollahpour Shiadeh M., Nyasulu P.S., Ogbo F.A., Oh I.-H., Olagunju A.T., Olagunju T.O., Olivares P.R., Onwujekwe O.E., Oren E., Owolabi M.O., A M.P., Pakpour A.H., Pan W.-H., Panda-Jonas S., Pandian J.D., Patel S.K., Pereira D.M., Petzold M., Pillay J.D., Piradov M.A., Polanczyk G.V., Polinder S., Postma M.J., Poulton R., Poustchi H., Prakash S., Prakash V., Qorbani M., Radfar A., Rafay A., Rafiei A., Rahim F., Rahimi-Movaghar V., Rahman M., Rahman M.H.U., Rahman M.A., Rajati F., Ram U., Ranta A., Rawaf D.L., Rawaf S., Reinig N., Reis C., Renzaho A.M.N., Resnikoff S., Rezaeian S., Rezai M.S., Rios Gonzalez C.M., Roberts N.L.S., Roever L., Ronfani L., Roro E.M., Roshandel G., Rostami A., Sabbagh P., Sacco R.L., Sachdev P.S., Saddik B., Safari H., Safari-Faramani R., Safi S., Safiri S., Sagar R., Sahathevan R., Sahebkar A., Sahraian M.A., Salamati P., Salehi Zahabi S., Salimi Y., Samy A.M., Sanabria J., Santos I.S., Santric Milicevic M.M., Sarrafzadegan N., Sartorius B., Sarvi S., Sathian B., Satpathy M., Sawant A.R., Sawhney M., Schneider I.J.C., Schottker B., Schwebel D.C., Seedat S., Sepanlou S.G., Shabaninejad H., Shafieesabet A., Shaikh M.A., Shakir R.A., Shams-Beyranvand M., Shamsizadeh M., Sharif M., Sharif-Alhoseini M., She J., Sheikh A., Sheth K.N., Shigematsu M., Shiri R., Shirkoohi R., Shiue I., Siabani S., Siddiqi T.J., Sigfusdottir I.D., Sigurvinsdottir R., Silberberg D.H., Silva J.P., Silveira D.G.A., Singh J.A., Sinha D.N., Skiadaresi E., Smith M., Sobaih B.H., Sobhani S., Soofi M., Soyiri I.N., Sposato L.A., Stein D.J., Stein M.B., Stokes M.A., Sufiyan M.B., Sykes B.L., Sylaja P., Tabares-Seisdedos R., Te Ao B.J., Tehrani-Banihashemi A., Temsah M.-H., Temsah O., Thakur J.S., Thrift A.G., Topor-Madry R., Tortajada-Girbes M., Tovani-Palone M.R., Tran B.X., Tran K.B., Truelsen T.C., Tsadik A.G., Tudor Car L., Ukwaja K.N., Ullah I., Usman M.S., Uthman O.A., Valdez P.R., Vasankari T.J., Vasanthan R., Veisani Y., Venketasubramanian N., Violante F.S., Vlassov V., Vosoughi K., Vu G.T., Vujcic I.S., Wagnew F.S., Waheed Y., Wang Y.-P., Weiderpass E., Weiss J., Whiteford H.A., Wijeratne T., Winkler A.S., Wiysonge C.S., Wolfe C.D.A., Xu G., Yadollahpour A., Yamada T., Yano Y., Yaseri M., Yatsuya H., Yimer E.M., Yip P., Yisma E., Yonemoto N., Yousefifard M., Yu C., Zaidi Z., Zaman S.B., Zamani M., Zandian H., Zare Z., Zhang Y., Zodpey S., Naghavi M., Murray C.J.L., Vos T., Public Health, Feigin, Valery L, Nichols, Emma, Alam, Tahiya, Bannick, Marlena S, Ahmed, Muktar Beshir, Yisma, Engida, Vos, Theo, GBD 2016 Neurology Collaborators, Viðskiptadeild (HR), School of Business (RU), Háskólinn í Reykjavík, Reykjavik University, Feigin, V, Nichols, E, Alam, T, Bannick, M, Beghi, E, Blake, N, Culpepper, W, Dorsey, E, Elbaz, A, Ellenbogen, R, Fisher, J, Fitzmaurice, C, Giussani, G, Glennie, L, James, S, Johnson, C, Kassebaum, N, Logroscino, G, Marin, B, Mountjoy-Venning, W, Nguyen, M, Ofori-Asenso, R, Patel, A, Piccininni, M, Roth, G, Steiner, T, Stovner, L, Szoeke, C, Theadom, A, Vollset, S, Wallin, M, Wright, C, Zunt, J, Abbasi, N, Abd-Allah, F, Abdelalim, A, Abdollahpour, I, Aboyans, V, Abraha, H, Acharya, D, Adamu, A, Adebayo, O, Adeoye, A, Adsuar, J, Afarideh, M, Agrawal, S, Ahmadi, A, Ahmed, M, Aichour, A, Aichour, I, Aichour, M, Akinyemi, R, Akseer, N, Al-Eyadhy, A, Al-Shahi Salman, R, Alahdab, F, Alene, K, Aljunid, S, Altirkawi, K, Alvis-Guzman, N, Anber, N, Antonio, C, Arabloo, J, Aremu, O, Ärnlöv, J, Asayesh, H, Asghar, R, Atalay, H, Awasthi, A, Ayala Quintanilla, B, Ayuk, T, Badawi, A, Banach, M, Banoub, J, Barboza, M, Barker-Collo, S, Bärnighausen, T, Baune, B, Bedi, N, Behzadifar, M, Béjot, Y, Bekele, B, Belachew, A, Bennett, D, Bensenor, I, Berhane, A, Beuran, M, Bhattacharyya, K, Bhutta, Z, Biadgo, B, Bijani, A, Bililign, N, Bin Sayeed, M, Blazes, C, Brayne, C, Butt, Z, Campos-Nonato, I, Cantu-Brito, C, Car, M, Cárdenas, R, Carrero, J, Carvalho, F, Castañeda-Orjuela, C, Castro, F, Catalá-López, F, Cerin, E, Chaiah, Y, Chang, J, Chatziralli, I, Chiang, P, Christensen, H, Christopher, D, Cooper, C, Cortesi, P, Costa, V, Criqui, M, Crowe, C, Damasceno, A, Daryani, A, De la Cruz-Góngora, V, De la Hoz, F, De Leo, D, Demoz, G, Deribe, K, Dharmaratne, S, Diaz, D, Dinberu, M, Djalalinia, S, Doku, D, Dubey, M, Dubljanin, E, Duken, E, Edvardsson, D, El-Khatib, Z, Endres, M, Endries, A, Eskandarieh, S, Esteghamati, A, Esteghamati, S, Farhadi, F, Faro, A, Farzadfar, F, Farzaei, M, Fatima, B, Fereshtehnejad, S, Fernandes, E, Feyissa, G, Filip, I, Fischer, F, Fukumoto, T, Ganji, M, Gankpe, F, Garcia-Gordillo, M, Gebre, A, Gebremichael, T, Gelaw, B, Geleijnse, J, Geremew, D, Gezae, K, Ghasemi-Kasman, M, Gidey, M, Gill, P, Gill, T, Girma, E, Gnedovskaya, E, Goulart, A, Grada, A, Grosso, G, Guo, Y, Gupta, R, Haagsma, J, Hagos, T, Haj-Mirzaian, A, Hamadeh, R, Hamidi, S, Hankey, G, Hao, Y, Haro, J, Hassankhani, H, Hassen, H, Havmoeller, R, Hay, S, Hegazy, M, Heidari, B, Henok, A, Heydarpour, F, Hoang, C, Hole, M, Homaie Rad, E, Hosseini, S, Hu, G, Igumbor, E, Ilesanmi, O, Irvani, S, Islam, S, Jakovljevic, M, Javanbakht, M, Jha, R, Jobanputra, Y, Jonas, J, Jozwiak, J, Jürisson, M, Kahsay, A, Kalani, R, Kalkonde, Y, Kamil, T, Kanchan, T, Karami, M, Karch, A, Karimi, N, Kasaeian, A, Kassa, T, Kassa, Z, Kaul, A, Kefale, A, Keiyoro, P, Khader, Y, Khafaie, M, Khalil, I, Khan, E, Khang, Y, Khazaie, H, Kiadaliri, A, Kiirithio, D, Kim, A, Kim, D, Kim, Y, Kisa, A, Kokubo, Y, Koyanagi, A, Krishnamurthi, R, Kuate Defo, B, Kucuk Bicer, B, Kumar, M, Lacey, B, Lafranconi, A, Lansingh, V, Latifi, A, Leshargie, C, Li, S, Liao, Y, Linn, S, Lo, W, Lopez, J, Lorkowski, S, Lotufo, P, Lucas, R, Lunevicius, R, Mackay, M, Mahotra, N, Majdan, M, Majdzadeh, R, Majeed, A, Malekzadeh, R, Malta, D, Manafi, N, Mansournia, M, Mantovani, L, März, W, Mashamba-Thompson, T, Massenburg, B, Mate, K, Mcalinden, C, Mcgrath, J, Mehta, V, Meier, T, Meles, H, Melese, A, Memiah, P, Memish, Z, Mendoza, W, Mengistu, D, Mengistu, G, Meretoja, A, Meretoja, T, Mestrovic, T, Miazgowski, B, Miazgowski, T, Miller, T, Mini, G, Mirrakhimov, E, Moazen, B, Mohajer, B, Mohammad Gholi Mezerji, N, Mohammadi, M, Mohammadi-Khanaposhtani, M, Mohammadibakhsh, R, Mohammadnia-Afrouzi, M, Mohammed, S, Mohebi, F, Mokdad, A, Monasta, L, Mondello, S, Moodley, Y, Moosazadeh, M, Moradi, G, Moradi-Lakeh, M, Moradinazar, M, Moraga, P, Moreno Velásquez, I, Morrison, S, Mousavi, S, Muhammed, O, Muruet, W, Musa, K, Mustafa, G, Naderi, M, Nagel, G, Naheed, A, Naik, G, Najafi, F, Nangia, V, Negoi, I, Negoi, R, Newton, C, Ngunjiri, J, Nguyen, C, Nguyen, L, Ningrum, D, Nirayo, Y, Nixon, M, Norrving, B, Noubiap, J, Nourollahpour Shiadeh, M, Nyasulu, P, Ogah, O, Oh, I, Olagunju, A, Olagunju, T, Olivares, P, Onwujekwe, O, Oren, E, Owolabi, M, Pa, M, Pakpour, A, Pan, W, Panda-Jonas, S, Pandian, J, Patel, S, Pereira, D, Petzold, M, Pillay, J, Piradov, M, Polanczyk, G, Polinder, S, Postma, M, Poulton, R, Poustchi, H, Prakash, S, Prakash, V, Qorbani, M, Radfar, A, Rafay, A, Rafiei, A, Rahim, F, Rahimi-Movaghar, V, Rahman, M, Rajati, F, Ram, U, Ranta, A, Rawaf, D, Rawaf, S, Reinig, N, Reis, C, Renzaho, A, Resnikoff, S, Rezaeian, S, Rezai, M, Rios González, C, Roberts, N, Roever, L, Ronfani, L, Roro, E, Roshandel, G, Rostami, A, Sabbagh, P, Sacco, R, Sachdev, P, Saddik, B, Safari, H, Safari-Faramani, R, Safi, S, Safiri, S, Sagar, R, Sahathevan, R, Sahebkar, A, Sahraian, M, Salamati, P, Salehi Zahabi, S, Salimi, Y, Samy, A, Sanabria, J, Santos, I, Santric Milicevic, M, Sarrafzadegan, N, Sartorius, B, Sarvi, S, Sathian, B, Satpathy, M, Sawant, A, Sawhney, M, Schneider, I, Schöttker, B, Schwebel, D, Seedat, S, Sepanlou, S, Shabaninejad, H, Shafieesabet, A, Shaikh, M, Shakir, R, Shams-Beyranvand, M, Shamsizadeh, M, Sharif, M, Sharif-Alhoseini, M, She, J, Sheikh, A, Sheth, K, Shigematsu, M, Shiri, R, Shirkoohi, R, Shiue, I, Siabani, S, Siddiqi, T, Sigfusdottir, I, Sigurvinsdottir, R, Silberberg, D, Silva, J, Silveira, D, Singh, J, Sinha, D, Skiadaresi, E, Smith, M, Sobaih, B, Sobhani, S, Soofi, M, Soyiri, I, Sposato, L, Stein, D, Stein, M, Stokes, M, Sufiyan, M, Sykes, B, Sylaja, P, Tabarés-Seisdedos, R, Te Ao, B, Tehrani-Banihashemi, A, Temsah, M, Temsah, O, Thakur, J, Thrift, A, Topor-Madry, R, Tortajada-Girbés, M, Tovani-Palone, M, Tran, B, Tran, K, Truelsen, T, Tsadik, A, Tudor Car, L, Ukwaja, K, Ullah, I, Usman, M, Uthman, O, Valdez, P, Vasankari, T, Vasanthan, R, Veisani, Y, Venketasubramanian, N, Violante, F, Vlassov, V, Vosoughi, K, Vu, G, Vujcic, I, Wagnew, F, Waheed, Y, Wang, Y, Weiderpass, E, Weiss, J, Whiteford, H, Wijeratne, T, Winkler, A, Wiysonge, C, Wolfe, C, Xu, G, Yadollahpour, A, Yamada, T, Yano, Y, Yaseri, M, Yatsuya, H, Yimer, E, Yip, P, Yisma, E, Yonemoto, N, Yousefifard, M, Yu, C, Zaidi, Z, Zaman, S, Zamani, M, Zandian, H, Zare, Z, Zhang, Y, Zodpey, S, Naghavi, M, Murray, C, Vos, T, PharmacoTherapy, -Epidemiology and -Economics, Value, Affordability and Sustainability (VALUE), Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET), Microbes in Health and Disease (MHD), Lee Kong Chian School of Medicine (LKCMedicine), Clinicum, Department of Neurosciences, Neurologian yksikkö, Department of Surgery, University of Helsinki, II kirurgian klinikka, and HUS Comprehensive Cancer Center
Subjects: Dánarmein, Male, Epidemiology, Diseases, Malalties cerebrals, Global Burden of Disease, Disability Evaluation, 0302 clinical medicine, Case fatality rate, Psychology, Konur, Cause of death, Aged, 80 and over, education.field_of_study, Incidence, Men, Taugavísindi, ddc, 3. Good health, Sálfræði, World health, Muerte, Neurology, GBD 2016 Neurology Collaborators, Brain diseases, Quality-Adjusted Life Years, Alzheimer disease, Carga global de enfermedades, Nervous system, medicine.medical_specialty, Global burden of diseases, Lífsgæði, Article, 03 medical and health sciences, Health Sciences, Humans, Women, education, Trastornos neurológicos, VLAG, Aged, Science & Technology, 3112 Neurosciences, Global Burden of Diseases, 030104 developmental biology, Years of potential life lost, Επιστήμες Υγείας, Dementia, Human medicine, Neurosciences & Neurology, Neurology (clinical), Clinical Medicine, 1109 Neurosciences, Neurological disorders, 030217 neurology & neurosurgery, dementia, RC, 0301 basic medicine, Pediatrics, Dánartíðni, Nutrition and Disease, 3124 Neurology and psychiatry, Disease Study, Taugasjúkdómar, Risk Factors, Voeding en Ziekte, Cause of Death, Global health, Prevalence, Causes of death, Public health, Mortality rate, Mental Disorders, Age Factors, Public Health, Global Health, Social Medicine and Epidemiology, Middle Aged, neurologic disease, Death, Lýðheilsa, Female, Life Sciences & Biomedicine, Quality of life, Adult, Population, Clinical Neurology, Sex Factors, medicine, Life Science, Disability-adjusted life year, Medicine [Science], Mortality, Psychiatry, Disease burden, Neurology & Neurosurgery, burden of neurological disorders, Faraldsfræði, business.industry, Klinisk medicin, Causes de la mort, 1103 Clinical Sciences, Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi, Socioeconomic Factors, Karlar, global disease burden, Nervous System Diseases, Cause of death/trends, business
Abstract: Publisher´s version (útgefin grein)., Background Neurological disorders are increasingly recognised as major causes of death and disability worldwide. The aim of this analysis from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 is to provide the most comprehensive and up-to-date estimates of the global, regional, and national burden from neurological disorders.Methods We estimated prevalence, incidence, deaths, and disability-adjusted life-years (DALYs; the sum of years of life lost [YLLs] and years lived with disability [YLDs]) by age and sex for 15 neurological disorder categories (tetanus, meningitis, encephalitis, stroke, brain and other CNS cancers, traumatic brain injury, spinal cord injury, Alzheimer’s disease and other dementias, Parkinson’s disease, multiple sclerosis, motor neuron diseases, idiopathic epilepsy, migraine, tension-type headache, and a residual category for other less common neurological disorders) in 195 countries from 1990 to 2016. DisMod-MR 2.1, a Bayesian meta-regression tool, was the main method of estimation of prevalence and incidence, and the Cause of Death Ensemble model (CODEm) was used for mortality estimation. We quantified the contribution of 84 risks and combinations of risk to the disease estimates for the 15 neurological disorder categories using the GBD comparative risk assessment approach.Findings Globally, in 2016, neurological disorders were the leading cause of DALYs (276 million [95% UI 247–308]) and second leading cause of deaths (9·0 million [8·8–9·4]). The absolute number of deaths and DALYs from all neurological disorders combined increased (deaths by 39% [34–44] and DALYs by 15% [9–21]) whereas their age-standardised rates decreased (deaths by 28% [26–30] and DALYs by 27% [24–31]) between 1990 and 2016. The only neurological disorders that had a decrease in rates and absolute numbers of deaths and DALYs were tetanus, meningitis, and encephalitis. The four largest contributors of neurological DALYs were stroke (42·2% [38·6–46·1]), migraine (16·3% [11·7–20·8]), Alzheimer’s and other dementias (10·4% [9·0–12·1]), and meningitis (7·9% [6·6–10·4]). For the combined neurological disorders, age-standardised DALY rates were significantly higher in males than in females (male-to-female ratio 1·12 [1·05–1·20]), but migraine, multiple sclerosis, and tension-type headache were more common and caused more burden in females, with male-to-female ratios of less than 0·7. The 84 risks quantified in GBD explain less than 10% of neurological disorder DALY burdens, except stroke, for which 88·8% (86·5–90·9) of DALYs are attributable to risk factors, and to a lesser extent Alzheimer’s disease and other dementias (22·3% [11·8–35·1] of DALYs are risk attributable) and idiopathic epilepsy (14·1% [10·8–17·5] of DALYs are risk attributable).Interpretation Globally, the burden of neurological disorders, as measured by the absolute number of DALYs, continues to increase. As populations are growing and ageing, and the prevalence of major disabling neurological disorders steeply increases with age, governments will face increasing demand for treatment, rehabilitation, and support services for neurological disorders. The scarcity of established modifiable risks for most of the neurological burden demonstrates that new knowledge is required to develop effective prevention and treatment strategies., ROA is funded by the National Institutes of Health (U01HG010273). SMA acknowledges the International Centre for Casemix and Clinical Coding, Faculty of Medicine, National University of Malaysia and Department of Health Policy and Management, Faculty of Public Health, Kuwait University for the approval and support to participate in this research project. AAw acknowledges funding support from Department of Science and Technology, Government of India, New Delhi, through INSPIRE Faculty scheme. TBA acknowledges partial funding from the Institute of Medical Research and Medicinal Plant Studies. ABa is supported by the Public Health Agency of Canada. TWB was supported by the Alexander von Humboldt Foundation through the Alexander von Humboldt Professor Award, funded by the Federal Ministry of Education and Research. MSBS acknowledges support from the Australian Government Research and Training Program scholarship for a PhD degree at the Australian National University, Australia. JJC is supported by the Swedish Heart and Lung Foundation. FCar is supported by the European Union (FEDER funds POCI/01/0145/FEDER/007728 and POCI/01/0145/FEDER/007265) and National Funds (FCT/MEC, Fundacao para a Ciencia e a Tecnologia and Ministerio da Educacao e Ciencia) under the Partnership Agreements PT2020 UID/MULTI/04378/2013 and PT2020UID/QUI/50006/2013. EC is supported by an Australian Research Council Future Fellowship (FT3 140100085). KD is supported by a Wellcome Trust [Grant Number 201900] as part of his International Intermediate Fellowship. EF is supported by the European Union (FEDER funds POCI/01/0145/FEDER/007728 and POCI/01/0145/FEDER/007265) and National Funds (FCT/MEC, Fundacao para a Ciencia e a Tecnologia and Ministerio da Educacao e Ciencia) under the Partnership Agreements PT2020 UID/MULTI/04378/2013 and PT2020UID/QUI/50006/2013. SMSI is funded by the Institute for Physical Activity and Nutrition (IPAN), Deakin University and received funding from High Blood Pressure Research Council of Australia. YKa is a DBT/Wellcome Trust India Alliance Fellow in Public Health. YJK is supported by the Office of Research and Innovation at Xiamen University Malaysia. BL acknowledges funding from the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre. WDL is supported in part by U10NS086484 NINDS. SLo is funded by the German Federal Ministry of Education and Research (nutriCARD, grant agreement number 01EA1411A). RML is supported by a National Health and Medical Research Council (NHMRC) of Australia Senior Research Fellowship. AMa and the Imperial College London are grateful for support from the NW London NIHR Collaboration for Leadership in Applied Health Research and Care. JJM is supported by the Danish National Research Foundation (Niels Bohr Professorship), and the John Cade Fellowship (APP1056929) from NHMRC. TMei acknowledges additional institutional support from the Competence Cluster for Nutrition and Cardiovascular Health (nutriCARD), Jena-Halle-Leipzig. IMV is supported by the Sistema Nacional de Investigacion (Panama). MOO is supported by SIREN U54 U54HG007479 and SIBS Genomics R01NS107900 grants. AMS was supported by a fellowship from the Egyptian Fulbright Mission Program. MMSM acknowledges the support from the Ministry of Education, Science and Technological Development, Republic of Serbia (contract no 175087). AShe is supported by Health Data Research UK. MBS' work on traumatic brain injury is supported by grants NIH U01 NS086090 (PI G Manley) from the National Institutes of Health (NIH) and DoD W81XWH-14-2-0176 (PI G Manley) from the United States Department of Defense. RTS is supported in part by grant number PROMETEOII/2015/021 from Generalitat Valenciana and the national grant PI17/00719 from ISCIIIFEDER. AGT was supported by a Fellowship from the NHMRC (Australia; 1042600. KBT acknowledges funding supports from the Maurice Wilkins Centre for Biodiscovery, Cancer Society of New Zealand, Health Research Council, Gut Cancer Foundation, and the University of Auckland. CY acknowledges support from the National Natural Science Foundation of China (grant number 81773552) and the Chinese NSFC International Cooperation and Exchange Program (grant number 71661167007)., "Peer Reviewed"
Published: 2019

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23 results on '"Nyasulu P.S."'

1. P068 Knowledge Translation for Implementation of Point-of-Care Technology (POCT) in Breast Cancer Survivors in Africa: Descriptive study

2. Global injury morbidity and mortality from 1990 to 2017: results from the Global Burden of Disease Study 2017.

3. Global injury morbidity and mortality from 1990 to 2017: Results from the global burden of disease study 2017

4. Mapping child growth failure across low- and middle-income countries.

5. Mapping child growth failure across low- and middle-income countries

7. Global, regional, and national burden of traumatic brain injury and spinal cord injury, 1990-2016: A systematic analysis for the Global Burden of Disease Study 2016

8. Global, regional, and national burden of neurological disorders, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

10. Global, regional, and national age-sex-specific mortality and life expectancy, 1950-2017: A systematic analysis for the Global Burden of Disease Study 2017

11. Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017

12. Population and fertility by age and sex for 195 countries and territories, 1950–2017: a systematic analysis for the Global Burden of Disease Study 2017

13. Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2017: A systematic analysis for the Global Burden of Disease Study 2017

14. Global, regional, and national incidence, prevalence, and years lived with disability for 354 Diseases and Injuries for 195 countries and territories, 1990-2017: A systematic analysis for the Global Burden of Disease Study 2017

15. Global, regional, and national age-sex-specific mortality and life expectancy, 1950-2017: A systematic analysis for the Global Burden of Disease Study 2017.

16. Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017.

17. Global, regional, and national incidence, prevalence, and years lived with disability for 354 Diseases and Injuries for 195 countries and territories, 1990-2017: A systematic analysis for the Global Burden of Disease Study 2017.

18. Outcomes of multidrug resistant tuberculosis treatment among human immunodeficiency virus co-infected patients taking anti-retroviral treatment at Sizwe Tropical Disease Hospital Johannesburg, South Africa

19. Factors associated with high HIV related stigma among commuter populations in Johannesburg inner city, South Africa

20. Mapping disparities in education across low- and middle-income countries

21. Mapping child growth failure across low- and middle-income countries

22. Global, regional, and national burden of traumatic brain injury and spinal cord injury, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

23. Carga global, regional y nacional de neurológicas. Desórdenes, 1990-2016: un análisis sistemático para el Global Estudio de la carga de enfermedad 2016

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