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Background: Mouth rinsing (MR) with a carbohydrate solution is one of the most popular methods athletes use to improve their game-based performance due to its acute ergogenic effect. Objectives: This study aimed to evaluate the effects of the carbohydrate MR intervention on psychophysiological responses and kinematic profiles during intermittent (INT) and continuous (CON) 4-a-side small-sided soccer games (SSGs). Methods: Thirty-two adolescent soccer players (age: 16.5 ± 0.5 years) played six bouts of 4-a-side SSGs with MRINT or MRCON at 3-day intervals in a randomized, double-blinded, placebo-controlled, and crossover study design. Psychophysiological responses and kinematic profiles were continuously recorded during all games. The rating of perceived exertion (RPE), the rating scale of mental effort (RSME), and the physical enjoyment scores (PES) were also determined at the end of each game. Results: The MRCON induced higher psychophysiological responses such as RPE, internal training load (ITL), and RSME (p ≤ 0.05, d values ranging from 0.50 to 1.04 [small to moderate effect]). Conversely, the MRINT induced higher PES (p ≤ 0.05, d values = 1.44 [large effect]) compared to MRCON. Although the MR intervention led to similar improvements in the performance of 4-a-side MRINT and MRCON, there was no significant difference between the groups. Conclusions: Our results suggest that the MR intervention can be used as an effective ergogenic supplement for acute game performance enhancement, regardless of the game's structure. [ABSTRACT FROM AUTHOR]

In canine leishmaniosis (CanL), complex interactions between the parasites and the immunological background of the host influence the clinical presentation and evolution of infection and disease. Therefore, the potential use of nutraceuticals as immunomodulatory agents becomes of considerable interest. Some biological principles, mainly derived from plants and referred to as plant-derived nutraceuticals, are considered as supplementation for Leishmania spp. infection. This study provides a systematic review regarding the use of nutraceuticals as a treatment using a text mining (TM) and topic analysis (TA) approach to identify dominant topics of nutritional supplements in leishmaniosis-based research, summarize the temporal trend in topics, interpret the evolution within the last century and highlight any possible research gaps. Scopus® database was screened to select 18 records. Findings revealed an increasing trend in research records since 1994. TM identified terms with the highest weighted frequency and TA highlighted the main research areas, namely "Nutraceutical supports and their anti-inflammatory/antioxidant properties", "AHCC and nucleotides in CanL", "Vit. D3 and Leishmaniosis", "Functional food effects and Leishmaniosis" and "Extract effects and Leishmaniosis". Despite the existing academic interest, there are only a few studies on this issue so far, which reveals a gap in the literature that should be filled. [ABSTRACT FROM AUTHOR]

Edible caterpillars are an important food and economic resource for rural African people. However, they are subject to a number of threats; in particular, their host plants are threatened. The Luki Biosphere Reserve landscape is a region of the Democratic Republic of Congo where the practice of eating caterpillars is a recent phenomenon; however, rural communities have reported their scarcity. This study assessed the diversity and availability of host plants of the edible caterpillars in the Luki Biosphere Reserve (LBR) landscape. Botanical inventories were conducted in eleven ha plots of each of the following habitats: forest, savannah under protection, fallow, and inhabited areas, covering an area of 44 ha. The coverage-based rarefaction and extrapolation method and the iNEXT online software were used to calculate the true diversity of edible caterpillar host plants. The diameter structure of the edible caterpillar host plant species was assessed by counting the number of individuals in each diameter class. The results revealed that in the Luki Biosphere Reserve landscape, edible caterpillars rely on 15 main plant host species (Spondias mombin L., Petersianthus macrocarpus (P.Beauv.) Liben, Croton sylvaticus Hochst. ex Krauss, Hymenocardia acida Tul., Lannea welwitschii (Hiern) Engl., Macaranga spinosa Müll.Arg., Celtis mildbraedii Engl., Coelocaryon botryoïdes Vermoesen, Albizia gummifera (J.F.Gmel.) C. A. Sm, Bridelia atroviridis Müll.Arg, Ficus mucuso Welw. ex Ficalho, Funtumia elastica (P.Preuss) Stapf, Lannea welwitschii (Hiern) Engl., Milicia excelsa (Welw.) C.C. Berg., and Terminalia superba Engl. & Diels). The habitats exhibited low species diversity of the edible caterpillar host plants. Moreover, several of these species are becoming scarce or are locally threatened with extinction. The trend in the diametric structure is similar to species evolving in a disturbed environment.The results of this study suggest potential habitat instability linked to human activities that could lead to biodiversity loss and, thus, a decline in edible caterpillars in the LBR landscape. A better understanding of the unfavourable conditions that influence the nutritional support for the edible caterpillars would help promote appropriate strategies that can be applied in local development plans for community lands at a landscape scale.

In canine leishmaniosis (CanL), complex interactions between the parasites and the immunological background of the host influence the clinical presentation and evolution of infection and disease. Therefore, the potential use of nutraceuticals as immunomodulatory agents becomes of considerable interest. Some biological principles, mainly derived from plants and referred to as plant-derived nutraceuticals, are considered as supplementation for Leishmania spp. infection. This study provides a systematic review regarding the use of nutraceuticals as a treatment using a text mining (TM) and topic analysis (TA) approach to identify dominant topics of nutritional supplements in leishmaniosis-based research, summarize the temporal trend in topics, interpret the evolution within the last century and highlight any possible research gaps. Scopus® database was screened to select 18 records. Findings revealed an increasing trend in research records since 1994. TM identified terms with the highest weighted frequency and TA highlighted the main research areas, namely “Nutraceutical supports and their anti-inflammatory/antioxidant properties”, “AHCC and nucleotides in CanL”, “Vit. D3 and Leishmaniosis”, “Functional food effects and Leishmaniosis” and “Extract effects and Leishmaniosis”. Despite the existing academic interest, there are only a few studies on this issue so far, which reveals a gap in the literature that should be filled.

Muchos pacientes con etilismo crónico presentan un cuadro clínico de malnutrición, ya sea porque reducen la ingestión habitual de nutrientes esenciales o porque el alcohol impide la adecuada digestión y absorción de los distintos principios inmediatos, vitaminas y minerales. Un ejemplo común es el déficit de vitamina A en estos enfermos. Además, los propios procesos metabólicos del etanol (vía de la ADH y sistema MEOS) generan productos intermediarios tóxicos (acetaldehído, radicales libres) que interfieren con el metabolismo normal de los principios inmediatos, principalmente lípidos, originando daño celular a través de fenómenos de preoxidación lipídica y alteraciones de la fluidez de membranas, depósitos grasos (esteatosis hepatocelular), inflamación secundaria a estrés oxidativo y síntesis de citoquinas proinflamatorias, activación de células estrelladas y fibrogénesis, etc. Los soportes nutricionales pueden ser eficaces para mejorar la enfermedad hepática alcohólica. Se aconseja el aporte de una dieta equilibrada, suplementos vitamínicos y tratamiento farmacológico con antioxidantes para reponer los depósitos de glutatión reducido exhaustos. Es imprescindible que estos pacientes tengan una aproximación clínica multidisciplinaria para solucionar su problema de dependencia del alcohol.Many patients with chronic alcohol abuse present a clinical picture of malnourishment either because of reduced usual intake of essential nutrients or because alcohol precludes an appropriate digestion and absorption of the different essential elements, vitamins, and minerals. A usual example is vitamin A deficiency in these patients. Besides, ethanol metabolic pathways themselves (through the ADH and the MEOS system) generate toxic intermediate products (acetaldehyde, free radicals) interfering with normal metabolism of essential elements, mainly lipids, leading to cellular damage through lipid peroxidation mechanisms and impairment of the membrane fluidity, fat deposits (hepatocellular esteatosis), inflammation secondary to oxidative stress and proinflammatory cytokines, activation of stellate cells, fibrogenesis, etc. Nutritional supports may be effective to improve alcoholic liver disease. A balanced diet, vitamin supplements, and pharmacological therapy with antioxidants in order to recover depleted glutathione deposits are recommended. It is paramount that these patients have a multidisciplinary clinical approach to resolve the problem of alcohol dependency.

Many patients with chronic alcohol abuse present a clinical picture of malnourishment either because of reduced usual intake of essential nutrients or because alcohol precludes an appropriate digestion and absorption of the different essential elements, vitamins, and minerals. A usual example is vitamin A deficiency in these patients. Besides, ethanol metabolic pathways themselves (through the ADH and the MEOS system) generate toxic intermediate products (acetaldehyde, free radicals) interfering with normal metabolism of essential elements, mainly lipids, leading to cellular damage through lipid peroxidation mechanisms and impairment of the membrane fluidity, fat deposits (hepatocellular esteatosis), inflammation secondary to oxidative stress and proinflammatory cytokines, activation of stellate cells, fibrogenesis, etc. Nutritional supports may be effective to improve alcoholic liver disease. A balanced diet, vitamin supplements, and pharmacological therapy with antioxidants in order to recover depleted glutathione deposits are recommended. It is paramount that these patients have a multidisciplinary clinical approach to resolve the problem of alcohol dependency. [ABSTRACT FROM AUTHOR]