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The Sai Batin indigenous people use the “jujur” form of marriage the male majorate inheritance system, a system in which the oldest son is entitled to all inheritance and is the successor of their descendants. So strong is the position of sons in the family that if a family does not have a son, then the family is considered as having no or broken offspring. For this reason, in the Sai Batin kinship system, the adoption of a son, either from an internal or external family, is an alternative solution. This research is qualitative research using the Islamic Law Anthropology approach. In the data collection stage, the writer used the dept-interview technique combined with a survey. This research concludes that although most of the Sai Batin tribes still adhere to the customary inheritance system, however, there has been a tendency to no longer use customary law, especially in matters of inheritance, because it is considered unfair. This is indicated by the tendency of parents to bequeath property to all their children through a grant mechanism or to distribute inheritance based on Islamic inheritance law. This change is influenced by many factors, including the most dominant factors are education, economy, and social interaction.

AbstrakMalaria masih menjadi masalah kesehatan di dunia terutama negara tropis karena angka kesakitan dan kematiannya yang tinggi. Infeksi Plasmodium falciparum ini dapat menimbulkan gejala yang berat sampai kematian. Perbedaan perjalanan penyakit pada masing-masing individu salah satunya dipengaruhi oleh sistim imun. Di antara zat yang ikut berpengaruh pada imunitas malaria adalah TNF-α dan IL-10, yang dihasilkan oleh sistim pertahanan tubuh terhadap parasit ini. Tujuan penelitian ini adalah untuk mengetahui ekspresi TNF-α dan IL-10 pada infeksi malaria falciparum, menggunakan rancangan explanatory secara cross sectional, dan melibatkan 25 penderita malaria falciparum dengan umur berkisar 14 – 60 tahun. Kadar TNF-α dan IL-10 dianalisis dengan metoda enzyme-linked immunosorbent assay (ELISA), dan hasil analisis dinyatakan bermakna bila didapatkan p < 0,05. Penelitian menunjukkan adanya peningkatan kadar TNF-α dengan rerata 283,10 ± 267,72 pg/ml dan peningkatan kadar IL-10 dengan rerata 196,99 ± 131,94 pg/ml pada penderita malaria falciparum, yang dalam keadaan normal tidak terdeteksi. TNF-α berkorelasi positif dengan IL-10 (r = 0,491; p > 0,05), tapi berkorelasi negatif dengan kadar hemoglobin (r =-0,189; p > 0,05). IL-10 berkorelasi positif dengan kadar hemoglobin (r= 0,134; p > 0,05). Terhadap parasitemia, TNF-α berkorelasi positif (r=0,036; p > 0.05), namun IL-10 berkorelasi negatif (r = -0,043 dan p>0,05). Dari penelitian ini dapat disimpulkan bahwa infeksi malaria falciparum berpengaruh terhadap peningkatan kadar sitokin TNF-α dan IL-10.Kata kunci : TNF α – IL 10 – malaria falciparumAbstractMalaria is still a universal health problem, especially in tropical countries because of its high morbidity and mortality rates. Infection by Plasmodium falciparum could result in severe symptoms or even death. Differences in pathogenesis among affected individuals are affected by many factors, and the immune system is one of them. Among substances involved in the malarial immunity is TNF-α and IL-10, produced by the body's defense system as the reaction to the parasite. The objective of this study is to find expression of TNF-α and IL-10 on falciparum malaria infection, using an explanatory cross-sectional design, involving 25 people with falciparum malaria with age ranging from 14 to 60 years. The presence of TNF-α and IL-10 wereARTIKEL PENELITIAN17analyzed using enzyme linked immunosorbent assay (ELISA), and significant values considered at p < 0.05. The results show that there are increased rate of TNF-α with average 283.10 ± 267.72 pg/ml, and increased rate of IL-10 with average 196.99 ± 131.94 pg/ml among people with falciparum malaria, while in normal circumstances they are not detected. There is a positive correlation of TNF-α with IL-10 (r=0.491; p>0.05), but negative correlation with the rate of hemoglobin (r=-0189; p>0.05). IL-10 correlated positively with the rate of hemoglobin (r=0.134; p>0.05). TNF-α is positively correlated with parasitemia (r =0.036; p>0.05), but IL-10 is negatively correlated (r =-0043 and p>0.05). The results from this study conclude that falciparum malaria infection increases of TNF-α and IL-10 cytokine.Keywords: TNF α – IL 10 – falciparum malaria

This article presents an instance of the high-throughput-testing methodology called all-pairs testing, which provides software engineers and software testers the ability to get superb test coverage at very reasonable effort and cost. This advanced testing technique is shown to be more effective and efficient for both functional and nonfunctional aspects of software testing when compared to more traditional methods. This testing technique also provides the additional benefit of providing orthogonal or nearly orthogonal test designs for the purpose of evaluating the test parameters independently. [ABSTRACT FROM AUTHOR]