1. A new triterpenoid from Sapium baccatum (Euphorbiaceae)
- Author
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M. Izwan M. Yusof, Fatimah Salim, M. Nazip Suratman, Nurdiana Shamsulrijal, Norizan Ahmat, Norhazana Norizan, Farida Zuraina Mohd Yusof, S. Ruzaina S. Aris, and L. M. Ramadhan Al Muqarrabun
- Subjects
Stereochemistry ,Plant Science ,Mass spectrometry ,Sapium ,Biochemistry ,Analytical Chemistry ,Taraxerol ,chemistry.chemical_compound ,Mice ,Triterpenoid ,Triterpene ,Spectroscopy, Fourier Transform Infrared ,Acetone ,Organic chemistry ,Animals ,Humans ,Oleanolic Acid ,chemistry.chemical_classification ,biology ,Molecular Structure ,Plant Stems ,Organic Chemistry ,Euphorbiaceae ,3T3 Cells ,biology.organism_classification ,Antineoplastic Agents, Phytogenic ,Triterpenes ,Plant Leaves ,chemistry ,Sapium baccatum ,Drug Screening Assays, Antitumor ,Two-dimensional nuclear magnetic resonance spectroscopy ,HT29 Cells ,Algorithms - Abstract
A new triterpene, malaytaraxerate (1), and four known compounds, taraxerol (2), taraxerone (3), docosyl isoferulate (4) and docosanoic acid 2′,3′-dihydroxypropyl ester (5), were isolated from the acetone extract of Sapium baccatum stem bark. The structures of the isolated compounds were determined using several spectroscopic methods, including UV–Vis, FT-IR, 1D and 2D NMR, and mass spectrometry. Major isolated compounds were assayed for cytotoxicity. The chemotaxonomic significance of this plant was also studied.
- Published
- 2014
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