1,157 results on '"Nozawa T."'
Search Results
2. Abundances of ordinary chondrites in thermally evolving planetesimals
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Wakita, S., Hasegawa, Y., and Nozawa, T.
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Astrophysics - Earth and Planetary Astrophysics - Abstract
Chondrites are one of the most primitive objects in the solar system, and keep the record of the degree of thermal metamorphism experienced in their parent bodies. This thermal history can be classified by the petrologic type. We investigate the thermal evolution of planetesimals to account for the current abundances (known as the fall statistics) of petrologic types 3 - 6 ordinary chondrites. We carry out a number of numerical calculations in which formation times and sizes of planetesimals are taken as parameters. We find that planetesimals that form within 2.0 Myr after the formation of Ca-Al-rich inclusions (CAIs) can contain all petrologic types of ordinary chondrites. Our results also indicate that plausible scenarios of planetesimal formation, which are consistent with the fall statistics, are that planetesimals with radii larger than 60 km start to form around 2.0 Myr after CAIs and/or that ones with radii less than 50 km should be formed within 1.5 Myr after CAIs. Thus, thermal modelling of planetesimals is important for revealing the occurrence and amount of metamorphosed chondrites, and for providing invaluable insights into planetesimal formation., Comment: 16 pages, 13 figures, accepted for publication in ApJ
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- 2018
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3. Mechanical properties of self-ion irradiated pure tungsten using nano-indentation test and micro-tensile test
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Yu, J.H., Kurotaki, H., Ando, M., and Nozawa, T.
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- 2022
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4. Diffusion of Oxygen Isotopes in Thermally Evolving Planetesimals and Size Ranges of Presolar Silicate Grains
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Wakita, S., Nozawa, T., and Hasegawa, Y.
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Astrophysics - Earth and Planetary Astrophysics - Abstract
Presolar grains are small particles found in meteorites through their isotopic compositions which are considerably different from those of materials in the Solar System. If some isotopes in presolar grains diffused out beyond their grain sizes when they were embedded in parent bodies of meteorites, their isotopic compositions could be washed out, and hence the grains cannot be identified as presolar grains any more. We explore this possibility for the first time by self-consistently simulating the thermal evolution of planetesimals and the diffusion length of $^{18}$O in presolar silicate grains. Our results show that presolar silicate grains smaller than $\sim$ 0.03 $\mu m$ cannot keep their original isotopic compositions even if the host planetesimals experienced maximum temperature as low as 600 $^{\circ}$C. Since this temperature corresponds to the one experienced by petrologic type 3 chondrites, the isotopic diffusion can constrain the size of presolar silicate grains discovered in such chondrites to be larger than $\sim$ 0.03 $\mu m$. We also find that the diffusion lengths of $^{18}$O reach $\sim$ 0.3-2 $\mu m$ in planetesimals that were heated up to 700-800 $^{\circ}$C. This indicates that, if the original size of presolar grains spans a range from $\sim$ 0.001 $\mu m$ to $\sim$ 0.3 $\mu m$ like that in the interstellar medium, the isotopic records of the presolar grains may be almost completely lost in such highly thermalized parent bodies. We propose that isotopic diffusion could be a key process to control the size distribution and abundance of presolar grains in some types of chondrites., Comment: 7 pages, 2 figures, accepted for publication in ApJ
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- 2017
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5. DEMO structural materials qualification and development
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Gorley, M., Aiello, G., Henry, J., Nozawa, T., Pintsuk, G., Rieth, M., and Tanigawa, H.
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- 2021
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6. Extinction Laws toward Stellar Sources within a Dusty Circimstellar Medium and Implications for Type Ia Supernovae
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Nagao, T., Maeda, K., and Nozawa, T.
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Astrophysics - Solar and Stellar Astrophysics ,Astrophysics - High Energy Astrophysical Phenomena - Abstract
Many astronomical objects are surrounded by dusty environments. In such dusty objects, multiple scattering processes of photons by circumstellar (CS) dust grains can effectively alter extinction properties. In this paper, we systematically investigate effects of multiple scattering on extinction laws for steady-emission sources surrounded by the dusty CS medium, using a radiation transfer simulation based on the Monte Carlo technique. In particular, we focus on whether and how the extinction properties are affected by properties of CS dust grains, adopting various dust grain models. We {\bf confirm} that behaviors of the (effective) extinction laws are highly dependent on the properties of CS grains. Especially, the total-to-selective extinction ratio $R_{V}$, which characterizes the extinction law, can be either increased or decreased, compared to the case without multiple scattering. We find that the criterion for this behavior is given by a ratio of albedos in the $B$ and $V$ bands. We also find that either small silicate grains or polycyclic aromatic hydrocarbons (PAHs) are necessary for realizing a low value of $R_{V}$ as often measured toward Type Ia supernovae, if the multiple scattering by CS dust is responsible for their non-standard extinction laws. Using the derived relations between the properties of dust grains and the resulting effective extinction laws, we propose that the extinction laws toward dusty objects could be used to constrain the properties of dust grains in CS environments., Comment: 31 pages, 8 figures, 1 table, accepted for publication in ApJ
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- 2016
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7. Properties of Newly Formed Dust Grains in The Luminous Type IIn Supernova 2010jl
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Maeda, K., Nozawa, T., Sahu, D. K., Minowa, Y., Motohara, K., Ueno, I., Folatelli, G., Pyo, T. -S., Kitagawa, Y., Kawabata, K. S., Anupama, G. C., Kozasa, T., Moriya, T. J., Yamanaka, M., Nomoto, K., Bersten, M., Quimby, R., and Iye, M.
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Astrophysics - Solar and Stellar Astrophysics - Abstract
Supernovae (SNe) have been proposed to be the main production sites of dust grains in the Universe. Our knowledge on their importance to dust production is, however, limited by observationally poor constraints on the nature and amount of dust particles produced by individual SNe. In this paper, we present a spectrum covering optical through near-Infrared (NIR) light of the luminous Type IIn supernova (SN IIn) 2010jl around one and half years after the explosion. This unique data set reveals multiple signatures of newly formed dust particles. The NIR portion of the spectrum provides a rare example where thermal emission from newly formed hot dust grains is clearly detected. We determine the main population of the dust species to be carbon grains at a temperature of ~1,350 - 1,450K at this epoch. The mass of the dust grains is derived to be ~(7.5 - 8.5) x 10^{-4} Msun. Hydrogen emission lines show wavelength-dependent absorption, which provides a good estimate on the typical size of the newly formed dust grains (~0.1 micron, and most likely <~0.01 micron). We attribute the dust grains to have been formed in a dense cooling shell as a result of a strong SN-circumstellar media (CSM) interaction. The dust grains occupy ~10% of the emitting volume, suggesting an inhomogeneous, clumpy structure. The average CSM density is required to be >~3 x 10^{7} cm^{-3}, corresponding to a mass loss rate of >~0.02 Msun yr^{-1} (for a mass loss wind velocity of ~100 km s^{-1}). This strongly supports a scenario that SN 2010jl and probably other luminous SNe IIn are powered by strong interactions within very dense CSM, perhaps created by Luminous Blue Variable (LBV)-like eruptions within the last century before the explosion., Comment: 18 pages, 11 figures. Accepted by ApJ on 30 July 2013. The accepted version was submitted on 8 July 2013, and the original version was submitted on 3 March 2013
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- 2013
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8. SN 2009js at the crossroads between normal and subluminous Type IIP supernovae: optical and mid-infrared evolution
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Gandhi, P., Yamanaka, M., Tanaka, M., Nozawa, T., Kawabata, K. S., Saviane, I., Maeda, K., Moriya, T. J., Hattori, T., Sasada, M., and Itoh, R.
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Astrophysics - Solar and Stellar Astrophysics ,Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
We present a study of SN 2009js in NGC 918. Multi-band Kanata optical photometry covering the first ~120 days show the source to be a Type IIP SN. Reddening is dominated by that due to our Galaxy. One-year-post-explosion photometry with the NTT, and a Subaru optical spectrum 16 days post-discovery, both imply a good match with the well-studied subluminous SN 2005cs. The plateau phase luminosity of SN 2009js and its plateau duration are more similar to the intermediate luminosity IIP SN 2008in. Thus, SN 2009js shares characteristics with both subluminous and intermediate luminosity SNe. Its radioactive tail luminosity lies between SN 2005cs and SN 2008in, whereas its quasi-bolometric luminosity decline from peak to plateau (quantified by a newly-defined parameter Delta[logL] measuring adiabatic cooling following shock breakout) is much smaller than both the others. We estimate the ejected mass of 56Ni to be low (~0.007 Msun). The SN explosion energy appears to have been small, similar to SN 2005cs. SN 2009js is the first subluminous SN IIP to be studied in the mid-infrared. It was serendipitously caught by Spitzer at very early times. In addition, it was detected by WISE 105 days later with a significant 4.6 micron flux excess above the photosphere. The infrared excess luminosity relative to the photosphere is clearly smaller than that of SN 2004dj extensively studied in the mid-infrared. The excess may be tentatively assigned to heated dust with mass ~3e-5 Msun, or to CO fundamental emission as a precursor to dust formation., Comment: Accepted for publication in ApJ
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- 2013
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9. Dust in Historical Galactic Type Ia Supernova Remnants with Herschel
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Gomez, H. L., Clark, C. J. R., Nozawa, T., Krause, O., Gomez, E. L., Matsuura, M., Barlow, M. J., Besel, M. -A., Dunne, L., Gear, W. K., Hargrave, P., Henning, Th., Ivison, R. J., Sibthorpe, B., Swinyard, B. M., and Wesson, R.
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - Solar and Stellar Astrophysics - Abstract
The origin of interstellar dust in galaxies is poorly understood, particularly the relative contributions from supernovae and the cool stellar winds of low-intermediate mass stars. Here, we present Herschel PACS and SPIRE photometry at 70-500um of the historical young supernova remnants: Kepler and Tycho; both thought to be the remnants of Type Ia explosion events. We detect a warm dust component in Kepler's remnant with T = 82K and mass 0.0031Msun; this is spatially coincident with thermal X-ray emission optical knots and filaments, consistent with the warm dust originating in the circumstellar material swept up by the primary blast wave of the remnant. Similarly for Tycho's remnant, we detect warm dust at 90K with mass 0.0086Msun. Comparing the spatial distribution of the warm dust with X-rays from the ejecta and swept-up medium, and Ha emission arising from the post-shock edge, we show that the warm dust is swept up interstellar material. We find no evidence of a cool (25-50 K) component of dust with mass >0.07Msun as observed in core-collapse remnants of massive stars. Neither the warm or cold dust components detected here are spatially coincident with supernova ejecta material. We compare the lack of observed supernova dust with a theoretical model of dust formation in Type Ia remnants which predicts dust masses of 0.088(0.017)Msun for ejecta expanding into surrounding densities of 1(5)cm-3. The model predicts that silicon- and carbon-rich dust grains will encounter the interior edge of the observed dust emission at 400 years confirming that the majority of the warm dust originates from swept up circumstellar or interstellar grains (for Kepler and Tycho respectively). The lack of cold dust grains in the ejecta suggests that Type Ia remnants do not produce substantial quantities of iron-rich dust grains and has important consequences for the 'missing' iron mass observed in ejecta., Comment: 17 pages, 14 figures, accepted for publication in MNRAS, final version including corrected typos and references
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- 2011
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10. Extinction law in ultraluminous infrared galaxies at z ~ 1
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Shimizu, T., Kawara, K., Sameshima, H., Ienaka, N., Nozawa, T., and Kozasa, T.
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Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
We analyze the multi-wavelength photometric and spectroscopic data of 12 ultraluminous infrared galaxies (ULIRGs) at z ~ 1 and compare them with models of stars and dust in order to study the extinction law and star formation in young infrared (IR) galaxies. Five extinction curves, namely, the Milky Way (MW), the pseudo MW which is MW-like without the 2175 Angstrom feature, the Calzetti, and two SN dust curves, are applied to the data, by combining with various dust distributions, namely, the uniform dust screen, the clumpy dust screen, the internal dust geometry, and the composite geometry with a combination of dust screen and internal dust. Employing a minimum chi square method, we find that the foreground dust screen geometry, especially combined with the 8 - 40 M_sun SN extinction curve, provides a good approximation to the real dust geometry, whereas internal dust is only significant in 2 galaxies. The SN extinction curves, which are flatter than the others, reproduce the data of 8(67%) galaxies better. Dust masses are estimated to be in excess of ~ 10^8 M_sun. Inferred ages of the galaxies are very young, 8 of which range from 10 to 650 Myr. The SN-origin dust is the most plausible to account for the vast amount of dust masses and the flat slope of the observed extinction law. The inferred dust mass per SN ranges from 0.01 to 0.4 M_sun/SN., Comment: MNRAS in press, 14 pages, 4 figures, 8 tables
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- 2011
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11. Herschel Detects a Massive Dust Reservoir in Supernova 1987A
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Matsuura, M., Dwek, E., Meixner, M., Otsuka, M., Babler, B., Barlow, M. J., Roman-Duval, J., Engelbracht, C., Sandstrom, K., Lakicevic, M., van Loon, J. Th., Sonneborn, G., Clayton, G. C., Long, K. S., Lundqvist, P., Nozawa, T., Gordon, K. D., Hony, S., Panuzzo, P., Okumura, K., Misselt, K. A., Montiel, E., and Sauvage, M.
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Astrophysics - Solar and Stellar Astrophysics - Abstract
We report far-infrared and submillimeter observations of Supernova 1987A, the star that exploded on February 23, 1987 in the Large Magellanic Cloud, a galaxy located 160,000 lightyears away. The observations reveal the presence of a population of cold dust grains radiating with a temperature of ~17-23 K at a rate of about 220 solar luminosity. The intensity and spectral energy distribution of the emission suggests a dust mass of ~0.4-0.7 solar mass. The radiation must originate from the SN ejecta and requires the efficient precipitation of all refractory material into dust. Our observations imply that supernovae can produce the large dust masses detected in young galaxies at very high redshifts., Comment: This is the author's version of the work. It is posted here by permission of the AAAS for personal use, not for redistribution. To appear in Science; available in Science Express on 7th July, DOI:10.1126/science.1205983 at http://www.sciencemag.org/lookup/doi/10.1126/science.1205983 ; 14 pages, 2 figures, 4 tables. High resolution images are available from the authors
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- 2011
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12. Supernova dust for the extinction law in a young infrared galaxy at z = 1
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Kawara, K., Hirashita, H., Nozawa, T., Kozasa, T., Oyabu, S., Matsuoka, Y., Shimizu, T., Sameshima, H., and Ienaka, N.
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Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
We apply the supernova(SN) extinction curves to reproduce the observed properties of SST J1604+4304 which is a young infrared (IR) galaxy at z = 1. The SN extinction curves used in this work were obtained from models of unmixed ejecta of type II supernovae(SNe II) for the Salpeter initial mass function (IMF) with a mass range from 8 to 30 M_sun or 8 to 40 M_sun. The effect of dust distributions on the attenuation of starlight is investigated by performing the chi-square fitting method against various dust distributions. These are the commonly used uniform dust screen, the clumpy dust screen, and the internal dust geometry. We add to these geometries three scattering properties, namely, no-scattering, isotropic scattering, and forward-only scattering. Judging from the chi-square values, we find that the uniform screen models with any scattering property provide good approximations to the real dust geometry. Internal dust is inefficient to attenuate starlight and thus cannot be the dominant source of the extinction. We show that the SN extinction curves reproduce the data of SST J1604+4304 comparable to or better than the Calzetti extinction curve. The Milky Way extinction curve is not in satisfactory agreement with the data unless several dusty clumps are in the line of sight. This trend may be explained by the abundance of SN-origin dust in these galaxies; SN dust is the most abundant in the young IR galaxy at z = 1, abundant in local starbursts, and less abundant in the Galaxy. If dust in SST J1604+4304 is dominated by SN dust, the dust production rate is about 0.1 M_sun per SN., Comment: 12 pages, 8 figures, 1 table
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- 2010
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13. Observations of the Optical Transient in NGC 300 with AKARI/IRC: Possibilities of Asymmetric Dust Formation
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Ohsawa, R., Sakon, I., Onaka, T., Tanaka, M., Moriya, T., Nozawa, T., Maeda, K., Nomoto, K., Tominaga, N., Usui, F., Matsuhara, H., Nakagawa, T., and Murakami, H.
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Astrophysics - Solar and Stellar Astrophysics - Abstract
We present the results of near-infrared (NIR) multi-epoch observations of the optical transient in the nearby galaxy NGC300 (NGC300-OT) at 398 and 582 days after the discovery with the Infrared Camera (IRC) onboard AKARI. NIR spectra (2--5 um) of NGC300-OT were obtained for the first time. They show no prominent emission nor absorption features, but are dominated by continuum thermal emission from the dust around NGC300-OT. NIR images were taken in the 2.4, 3.2, and 4.1 um bands. The spectral energy distributions (SED) of NGC300-OT indicate the dust temperature of 810 (+-14) K at 398 days and 670 (+-12) K at 582 days. We attribute the observed NIR emission to the thermal emission from dust grains formed in the ejecta of NGC300-OT. The multi-epoch observations enable us to estimate the dust optical depth as larger than about 12 at 398 days and larger than about 6 at 582 days at 2.4 um, by assuming an isothermal dust cloud. The observed NIR emission must be optically thick, unless the amount of dust grains increases with time. Little extinction at visible wavelengths reported in earlier observations suggests that the dust cloud around NGC300-OT should be distributed inhomogeneously so as to not screen the radiation from the ejecta gas and the central star. The present results suggest the dust grains are not formed in spherically symmetric geometry, but rather in a torus, a bipolar outflow, or clumpy cloudlets., Comment: 4 pages, 2 figures, 2 tables; compiled with emulateapj; accepted in ApJ
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- 2010
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14. P2.13-04 Pathological Images Machine Learning Predicts Long Term Effects for Immunotherapy in Small-Cell Lung Cancer
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Shibaki, R., primary, Fujimoto, D., additional, Nozawa, T., additional, Hara, S., additional, Uchida, J., additional, Miyauchi, E., additional, Hiraoka, R., additional, Daga, H., additional, Masuda, T., additional, Tanaka, S., additional, Ikeda, S., additional, Saito, G., additional, Suzuki, H., additional, Sakata, S., additional, Sakata, Y., additional, Yamamoto, N., additional, Koh, Y., additional, and Akamatsu, H., additional
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- 2023
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15. Origin and Nature of Dust in the Early Universe
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Nozawa, T., Kozasa, T., Umeda, H., Hirashita, H., Maeda, K., Nomoto, K., Tominaga, N., Habe, A., Dwek, E., Takeuchi, T. T., and Ishii, T. T.
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Astrophysics - Abstract
We present recent advances in theoretical studies of the formation and evolution of dust in primordial supernovae (SNe) that are considered to be the main sources of dust in the early universe. Being combined with the results of calculations of dust formation in the ejecta of Population III SNe, the investigations of the evolution of newly formed dust within supernova remnants (SNRs) show that smaller grains are predominantly destroyed by sputtering in the shocked gas, while larger grains are injected into the ambient medium. The mass of dust grains surviving the destruction in SNRs reaches up to 0.1--15 $M_\odot$, which is high enough to account for the content of dust observed for the host galaxies of quasars at $z > 5$. In addition, the transport of dust formed in the ejecta causes the formation of low-mass stars in the dense shell of primordial SNRs and affects the elemental composition of those stars. We also show that the flat extinction curve is expected in the high-redshift universe where SNe are the possible sources of dust., Comment: 19 pages, 7 figures and 1 table, corrected typos, to appear in the ASP conference proceedings of "Cosmic Dust - Near and Far", Heidelberg, September 2008, eds. Th. Henning, E. Grun, & J. Steinacker
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- 2008
16. Early Formation of Dust in the Ejecta of Type Ib SN 2006jc and Temperature and Mass of the Dust
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Nozawa, T., Kozasa, T., Tominaga, N., Sakon, I., Tanaka, M., Suzuki, T., Nomoto, K., Maeda, K., Umeda, H., Limongi, M., and Onaka, T.
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Astrophysics - Abstract
SN 2006jc is a peculiar supernova (SN), in which the formation of dust has been confirmed at an early epoch of ~50 days after the explosion. We investigate the possibility of such an earlier formation of dust grains in the expanding ejecta of SN 2006jc, applying the Type Ib SN model that is developed to reproduce the observed light curve. We find that the rapid decrease of the gas temperature in SN 2006jc enables the condensation of C grains in the C-rich layer at 40-60 days after the explosion, which is followed by the condensation of silicate and oxide grains until ~200 days. The average radius of each grain species is confined to be less than 0.01 micron due to the low gas density at the condensation time. The calculated total dust mass reaches ~1.5 Msun, of which C dust shares 0.7 Msun. On the other hand, based on the calculated dust temperature, we show that the dust species and mass evaluated to reproduce the spectral energy distribution observed by AKARI and MAGNUM at day 200 are different from those obtained by the dust formation calculations; the dust species contributing to the observed flux are hot C and FeS grains with masses of $5.6 \times 10^{-4}$ Msun and $2.0 \times 10^{-3}$ Msun, respectively, though we cannot defy the presence of a large amount of cold dust such as silicate and oxide grains up to 0.5 Msun. One of the physical processes responsible for the difference between calculated and evaluated masses of C and FeS grains could be considered to be the destruction of small-sized clusters by energetic photons and electrons prevailing within the ejecta at the earlier epoch., Comment: 25 pages including 6 figures and 1 table. Accepted for publication in ApJ
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- 2008
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17. The Peculiar Type Ib Supernova 2006jc: A WCO Wolf-Rayet Star Explosion
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Tominaga, N., Limongi, M., Suzuki, T., Tanaka, M., Nomoto, K., Maeda, K., Chieffi, A., Tornambe, A., Minezaki, T., Yoshii, Y., Sakon, I., Wada, T., Ohyama, Y., Tanabé, T., Kaneda, H., Onaka, T., Nozawa, T., Kozasa, T., Kawabata, K. S., Anupama, G. C., Sahu, D. K., Gurugubelli, U. K., Prabhu, T. P., and Deng, J.
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Astrophysics - Abstract
We present a theoretical model for Type Ib supernova (SN) 2006jc. We calculate the evolution of the progenitor star, hydrodynamics and nucleosynthesis of the SN explosion, and the SN bolometric light curve (LC). The synthetic bolometric LC is compared with the observed bolometric LC constructed by integrating the UV, optical, near-infrared (NIR), and mid-infrared (MIR) fluxes. The progenitor is assumed to be as massive as $40M_\odot$ on the zero-age main-sequence. The star undergoes extensive mass loss to reduce its mass down to as small as $6.9M_\odot$, thus becoming a WCO Wolf-Rayet star. The WCO star model has a thick carbon-rich layer, in which amorphous carbon grains can be formed. This could explain the NIR brightening and the dust feature seen in the MIR spectrum. We suggest that the progenitor of SN 2006jc is a WCO Wolf-Rayet star having undergone strong mass loss and such massive stars are the important sites of dust formation. We derive the parameters of the explosion model in order to reproduce the bolometric LC of SN 2006jc by the radioactive decays: the ejecta mass $4.9M_\odot$, hypernova-like explosion energy $10^{52}$ ergs, and ejected $^{56}$Ni mass $0.22M_\odot$. We also calculate the circumstellar interaction and find that a CSM with a flat density structure is required to reproduce the X-ray LC of SN 2006jc. This suggests a drastic change of the mass-loss rate and/or the wind velocity that is consistent with the past luminous blue variable (LBV)-like event., Comment: 12 pages, 11 figures. Accepted for publication in the Astrophysical Journal
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- 2007
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18. Properties of newly formed dust by SN2006jc based on near-to-mid infrared observation with AKARI
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Sakon, I., Wada, T., Ohyama, Y., Ishihara, D., Tanabé, T., Kaneda, H., Onaka, T., Tominaga, N., Tanaka, M., Suzuki, T., Umeda, H., Nomoto, K., Nozawa, T., Kozasa, T., Minezaki, T., Yoshii, Y., Ohyabu, S., Usui, F., Matsuhara, H., Nakagawa, T., and Murakami, H.
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Astrophysics - Abstract
We present our latest results on near- to mid- infrared observation of SN2006jc at 200 days after the discovery using the Infrared Camera (IRC) on board $AKARI$. The near-infrared (2--5$\mu$m) spectrum of SN2006jc is obtained for the first time and is found to be well interpreted in terms of the thermal emission from amorphous carbon of 800$\pm 10$K with the mass of $6.9\pm 0.5 \times 10^{-5}M_{\odot}$ that was formed in the supernova ejecta. This dust mass newly formed in the ejecta of SN 2006jc is in a range similar to those obtained for other several dust forming core collapse supernovae based on recent observations (i.e., $10^{-3}$--$10^{-5}$$M_{\odot}$). Mid-infrared photometric data with {\it{AKARI}}/IRC MIR-S/S7, S9W, and S11 bands have shown excess emission over the thermal emission by hot amorphous carbon of 800K. This mid-infrared excess emission is likely to be accounted for by the emission from warm amorphous carbon dust of 320$\pm 10$K with the mass of 2.7$^{+0.7}_{-0.5} \times 10^{-3}M_{\odot}$ rather than by the band emission of astronomical silicate and/or silica grains. This warm amorphous carbon dust is expected to have been formed in the mass loss wind associated with the Wolf-Rayet stellar activity before the SN explosion. Our result suggests that a significant amount of dust is condensed in the mass loss wind prior to the SN explosion. A possible contribution of emission bands by precursory SiO molecules in 7.5--9.5$\mu$m is also suggested., Comment: 28 pages, 9 figures. Submitted to the Astrophysical Journal
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- 2007
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19. Attribution of polar warming to human influence
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Gillett, NP, Stone, DA, Stott, PA, Nozawa, T, Karpechko, AY, Hegerl, GC, Wehner, MF, and Jones, PD
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Meteorology & Atmospheric Sciences - Abstract
The polar regions have long been expected to warm strongly as a result of anthropogenic climate change, because of the positive feedbacks associated with melting ice and snow. Several studies have noted a rise in Arctic temperatures over recent decades, but have not formally attributed the changes to human influence, owing to sparse observations and large natural variability. Both warming and cooling trends have been observed in Antarctica, which the Intergovernmental Panel on Climate Change Fourth Assessment Report concludes is the only continent where anthropogenic temperature changes have not been detected so far, possibly as a result of insufficient observational coverage. Here we use an up-to-date gridded data set of land surface temperatures and simulations from four coupled climate models to assess the causes of the observed polar temperature changes. We find that the observed changes in Arctic and Antarctic temperatures are not consistent with internal climate variability or natural climate drivers alone, and are directly attributable to human influence. Our results demonstrate that human activities have already caused significant warming in both polar regions, with likely impacts on polar biology, indigenous communities, ice-sheet mass balance and global sea level. © 2008 Macmillan Publishers Limited.
- Published
- 2008
20. Identification of human-induced changes in atmospheric moisture content
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Santer, BD, Mears, C, Wentz, FJ, Taylor, KE, Gleckler, PJ, Wigley, TML, Barnett, TP, Boyle, JS, Brüggemann, W, Gillett, NP, Klein, SA, Meehl, GA, Nozawa, T, Pierce, DW, Stott, PA, Washington, WM, and Wehner, MF
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Climate Action ,Air Movements ,Atmosphere ,Climate ,Computer Simulation ,Earth ,Planet ,Ecology ,Greenhouse Effect ,Human Activities ,Humans ,Humidity ,Microwaves ,Sunlight ,Time Factors ,Water ,climate change ,climate modeling ,detection and attribution ,water vapor - Abstract
Data from the satellite-based Special Sensor Microwave Imager (SSM/I) show that the total atmospheric moisture content over oceans has increased by 0.41 kg/m(2) per decade since 1988. Results from current climate models indicate that water vapor increases of this magnitude cannot be explained by climate noise alone. In a formal detection and attribution analysis using the pooled results from 22 different climate models, the simulated "fingerprint" pattern of anthropogenically caused changes in water vapor is identifiable with high statistical confidence in the SSM/I data. Experiments in which forcing factors are varied individually suggest that this fingerprint "match" is primarily due to human-caused increases in greenhouse gases and not to solar forcing or recovery from the eruption of Mount Pinatubo. Our findings provide preliminary evidence of an emerging anthropogenic signal in the moisture content of earth's atmosphere.
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- 2007
21. POS0760 LONG-TERM PROGNOSTIC FOLLOW-UP OF PATIENTS WITH REFRACTORY SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS AFTER THE CLINICAL TRIAL OF TOCILIZUMAB AS A FIRST-LINE BIOLOGIC TREATMENT
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Miyamae, T., primary, Kawabe, T., additional, Nishimura, K., additional, Hattori, S., additional, Imagawa, T., additional, Ishii, T., additional, Ito, S., additional, Iwata, N., additional, Kamata, Y., additional, Kamiyama, Y., additional, Mizuta, M., additional, Mori, M., additional, Murase, A., additional, Nakagishi, Y., additional, Nakano, T., additional, Nakayamada, S., additional, Nozawa, T., additional, Ohya, T., additional, Okamoto, N., additional, Sato, K., additional, Sugita, Y., additional, Takei, S., additional, Tanaka, Y., additional, Tomiita, M., additional, Umebayashi, H., additional, Yamasaki, Y., additional, Nishimoto, N., additional, and Yokota, S., additional
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- 2023
- Full Text
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22. Tritium distributions in castellated structures of Be limiter tiles from JET-ITER-like wall experiments
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Lee, S., primary, Hatano, Y., additional, Masuzaki, S., additional, Oya, Y., additional, Tokitani, M., additional, Yajima, M., additional, Otsuka, T., additional, Ashikawa, N., additional, Torikai, Y., additional, Asakura, N., additional, Nakamura, H., additional, Kurotaki, H., additional, Hayashi, T., additional, Nozawa, T., additional, Ito, A.M., additional, Likonen, J., additional, Widdowson, A., additional, and Rubel, M., additional
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- 2023
- Full Text
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23. Tritium distributions in castellated structures of Be limiter tiles from JET-ITER-like wall experiments
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Lee, S., Hatano, Y., Masuzaki, S., Oya, Y., Tokitani, M., Yajima, M., Otsuka, T., Ashikawa, N., Torikai, Y., Asakura, N., Nakamura, H., Kurotaki, H., Hayashi, T., Nozawa, T., Ito, A. M., Likonen, J., Widdowson, A., Rubel, Marek, Contributors, J E T, Lee, S., Hatano, Y., Masuzaki, S., Oya, Y., Tokitani, M., Yajima, M., Otsuka, T., Ashikawa, N., Torikai, Y., Asakura, N., Nakamura, H., Kurotaki, H., Hayashi, T., Nozawa, T., Ito, A. M., Likonen, J., Widdowson, A., Rubel, Marek, and Contributors, J E T
- Abstract
Tritium retention in the castellated structure of beryllium limiters used in JET with the ITER-like wall (ILW) during the first (ILW1), third (ILW3) and all three (ILW1-3) campaigns were examined and evaluated. Tritium was deposited on the surfaces inside the castellation grooves together with deuterium, beryllium, oxygen, carbon and small amounts of metallic impurities such as nickel, copper and tungsten. The tritium content after the ILW1 campaign was greater than after the ILW3 campaign. This is attributed to the steadily decreasing amount of carbon impurities in JET from campaign to campaign. The majority of tritium was retained in shallow regions in the grooves, up to 2 mm from the entrance to the gap. It was comparable on all sides of the castellation, i.e. no difference has been detected between the toroidal and poloidal gaps. Secondly, the tritium retention in the gaps was similar on all specimens independent of their position in the tokamak, while the retention on the plasma-facing surfaces clearly depended on the tile position. The tritium deposition patterns in the castellation were also compared with the deuterium distribution determined in earlier studies., QC 20230403
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- 2023
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24. Prevalent emm types and superantigen gene patterns of group A Streptococcus in Thailand
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PAVEENKITTIPORN, W., NOZAWA, T., DEJSIRILERT, S., NAKAGAWA, I., and HAMADA, S.
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- 2016
25. Dynamic measurements of radiation-induced electrical-property modifications in CVD-SiC under fast-neutron irradiation
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Tsuchiya, B., Shikama, T., Nagata, S., Saito, K., and Nozawa, T.
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- 2014
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26. Current status and recent research achievements in SiC/SiC composites
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Katoh, Y., Snead, L.L., Henager, C.H., Jr., Nozawa, T., Hinoki, T., Iveković, A., Novak, S., and Gonzalez de Vicente, S.M.
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- 2014
- Full Text
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27. Estimation of Precipitation Variation in River Basin Scale with GCM Outputs
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International Conference on Water Resources and Environment Research (4th : 2008 : Adelaide, S. Aust.), Kojiri, T, Kobayashi, T, and Nozawa, T
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- 2008
28. Measurements of Ribulose 1, 5-Bisphosphate Carboxylase/Oxygenase Activities by NMR
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Wang, Z.-Y., Luo, S., Sato, K., Kobayashi, M., Nozawa, T., and Garab, G., editor
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- 1998
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29. Detection and Attribution of Streamflow Timing Changes to Climate Change in the Western United States
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Hidalgo, H. G., Das, T., Dettinger, M. D., Cayan, D. R., Pierce, D. W., Barnett, T. P., Bala, G., Mirin, A., Wood, A. W., Bonfils, C., Santer, B. D., and Nozawa, T.
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- 2009
30. Silicon carbide composites as fusion power reactor structural materials
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Snead, L.L., Nozawa, T., Ferraris, M., Katoh, Y., Shinavski, R., and Sawan, M.
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- 2011
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31. Tensile test technique for composites using small notched specimens
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Nozawa, T. and Tanigawa, H.
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- 2011
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32. Recent progress in blanket materials development in the Broader Approach activities
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Nishitani, T., Tanigawa, H., Nozawa, T., Jitsukawa, S., Nakamichi, M., Hoshino, T., Yamanishi, T., Baluc, N., Möslang, A., Lindou, R., Tosti, S., Hodgson, E.R., Clement Lorenzo, S., Kohyama, A., Kimura, A., Shikama, T., Hayashi, K., and Araki, M.
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- 2011
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33. Effect of Carbon on Quantitative Evaluation of Hydrogen Atoms Trapped at Vacancy-type Defects Using Positron Annihilation Spectroscopy in Tungsten
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Sato, K., Hirabaru, M., Onoue, M., Hatakeyama, M., Xu, Q., Watanabe, Y., Nozawa, T., Yoshiyuki, Watanabe, and Takashi, Nozawa
- Subjects
Physics::Atomic Physics - Abstract
In fusion reactor materials, a large amount of gas atoms are formed by the nuclear reaction. The hydrogen isotopes interact with the irradiation-induced defects, and remain in the materials. Retention of hydrogen isotopes leads to a decrease in mechanical properties of materials, e.g. hydrogen embrittlement. Therefore, to study the interaction between hydrogen and defects is especially important. Positron annihilation spectroscopy (PAS) is a non-destructive technique for detecting vacancy type defects. In this study, the possibility of quantitative evaluation of hydrogen atoms trapped at vacancy-type defects using the PAS was investigated in the tungsten hydrogen-charged under different conditions., 20th International Conference of Fusion Reactor Materials
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- 2021
34. Effect of elastic strain on the stability of vacancy-carbon-hydrogen complexes in α-iron
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Hirayama, M., Sato, K., Kato, D., Watanabe, Y., Nozawa, T., Yoshiyuki, Watanabe, and Takashi, Nozawa
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Condensed Matter::Materials Science ,Physics::Atomic Physics - Abstract
One of the characteristics of a fusion reactor is that a large amount of gas atoms such as hydrogen and helium are produced by a transmutation reaction. The hydrogen isotopes interact with irradiation-induced defects and are retained in the material. This leads to the change in the mechanical properties of the material (hydrogen embrittlement etc.). Elastic strain is high near the edge dislocation cores or coherent interfaces. The strain has an effect on the hydrogen solution, and the binding energy of hydrogen to defects. Therefore, the investigation of interaction between hydrogen and defects under elastic strain is important. The purpose of this study is to obtain the binding energy of hydrogen atoms to vacancies and vacancy-carbon complexes under elastic strain in α-Fe, and to estimate the hydrogen retention in the strained Fe., 20th International Conference of Fusion Reactor Materials
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- 2021
35. A Broadband, Low Driving Voltage 2 × 2 Ti:LiNbO3 Optical Switch
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Nozawa, T., Yanagibashi, M., Miyazawa, H., Kawano, K., Jumonji, H., Auston, David H., editor, Engl, Walter, editor, Sugano, Takuo, editor, Lotsch, Helmut K. V., editor, Tada, Kunio, editor, and Hinton, H. Scott, editor
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- 1990
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36. R&D Activities for Fusion DEMO in the QST Rokkasho Fusion Institute
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Ishii, Y., primary, Aiba, N., additional, Ando, M., additional, Asakura, N., additional, Bierwage, A., additional, Cara, P., additional, Dzitko, H., additional, Edao, Y., additional, Gex, D., additional, Hasegawa, K., additional, Hayashi, T., additional, Hiwatari, R., additional, Hoshino, T., additional, Ikeda, Y., additional, Ishida, S., additional, Isobe, K., additional, Iwai, Y., additional, Jokinen, A., additional, Kasugai, A., additional, Kawamura, Y., additional, Kim, J. H., additional, Kondo, K., additional, Kwon, S., additional, Lorenzo, S. C., additional, Masuda, K., additional, Matsuyama, A., additional, Miyato, N., additional, Morishita, K., additional, Nakajima, M., additional, Nakajima, N., additional, Nakamichi, M., additional, Nozawa, T., additional, Ochiai, K., additional, Ohta, M., additional, Oyaidzu, M., additional, Ozeki, T., additional, Sakamoto, K., additional, Sakamoto, Y., additional, Sato, S., additional, Seto, H., additional, Shiroto, T., additional, Someya, Y., additional, Sugimoto, M., additional, Tanigawa, H., additional, Tokunaga, S., additional, Utoh, H., additional, Wang, W., additional, Watanabe, Y., additional, and Yagi, M., additional
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- 2021
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37. Future climate change: Implications for Indian summer monsoon and its variability
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Lal, Murari, Nozawa, T., Emori, S., Harasawa, H., Takahashi, K., Kimoto, M., Abe-Ouchi, A., Nakajima, T., Takemura, T., and Numaguti, A.
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- 2001
38. The effect of neutron irradiation on the fiber/matrix interphase of silicon carbide composites
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Nozawa, T., Katoh, Y., and Snead, L.L.
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- 2009
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39. Effects of specific adsorption of copper (II) ion on charge transfer reaction at the thin film LiMn 2O 4 electrode/aqueous electrolyte interface
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Nakayama, N., Yamada, I., Huang, Y., Nozawa, T., Iriyama, Y., Abe, T., and Ogumi, Z.
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- 2009
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40. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
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Klionsky, DJ, Abdel-Aziz, AK, Abdelfatah, S, Abdellatif, M, Abdoli, A, Abel, S, Abeliovich, H, Abildgaard, MH, Abudu, YP, Acevedo-Arozena, A, Adamopoulos, IE, Adeli, K, Adolph, TE, Adornetto, A, Aflaki, E, Agam, G, Agarwal, A, Aggarwal, BB, Agnello, M, Agostinis, P, Agrewala, JN, Agrotis, A, Aguilar, PV, Ahmad, ST, Ahmed, ZM, Ahumada-Castro, U, Aits, S, Aizawa, S, Akkoc, Y, Akoumianaki, T, Akpinar, HA, Al-Abd, AM, Al-Akra, L, Al-Gharaibeh, A, Alaoui-Jamali, MA, Alberti, S, Alcocer-Gómez, E, Alessandri, C, Ali, M, Alim Al-Bari, MA, Aliwaini, S, Alizadeh, J, Almacellas, E, Almasan, A, Alonso, A, Alonso, GD, Altan-Bonnet, N, Altieri, DC, Álvarez, ÉMC, Alves, S, Alves da Costa, C, Alzaharna, MM, Amadio, M, Amantini, C, Amaral, C, Ambrosio, S, Amer, AO, Ammanathan, V, An, Z, Andersen, SU, Andrabi, SA, Andrade-Silva, M, Andres, AM, Angelini, S, Ann, D, Anozie, UC, Ansari, MY, Antas, P, Antebi, A, Antón, Z, Anwar, T, Apetoh, L, Apostolova, N, Araki, T, Araki, Y, Arasaki, K, Araújo, WL, Araya, J, Arden, C, Arévalo, M-A, Arguelles, S, Arias, E, Arikkath, J, Arimoto, H, Ariosa, AR, Armstrong-James, D, Arnauné-Pelloquin, L, Aroca, A, Arroyo, DS, Arsov, I, Artero, R, Asaro, DML, Aschner, M, Ashrafizadeh, M, Ashur-Fabian, O, Atanasov, AG, Au, AK, Auberger, P, Auner, HW, Aurelian, L, Autelli, R, Avagliano, L, Ávalos, Y, Aveic, S, Aveleira, CA, Avin-Wittenberg, T, Aydin, Y, Ayton, S, Ayyadevara, S, Azzopardi, M, Baba, M, Backer, JM, Backues, SK, Bae, D-H, Bae, O-N, Bae, SH, Baehrecke, EH, Baek, A, Baek, S-H, Baek, SH, Bagetta, G, Bagniewska-Zadworna, A, Bai, H, Bai, J, Bai, X, Bai, Y, Bairagi, N, Baksi, S, Balbi, T, Baldari, CT, Balduini, W, Ballabio, A, Ballester, M, Balazadeh, S, Balzan, R, Bandopadhyay, R, Banerjee, S, Bánréti, Á, Bao, Y, Baptista, MS, Baracca, A, Barbati, C, Bargiela, A, Barilà, D, Barlow, PG, Barmada, SJ, Barreiro, E, Barreto, GE, Bartek, J, Bartel, B, Bartolome, A, Barve, GR, Basagoudanavar, SH, Bassham, DC, Bast, RC, Basu, A, Batoko, H, Batten, I, Baulieu, EE, Baumgarner, BL, Bayry, J, Beale, R, Beau, I, Beaumatin, F, Bechara, LRG, Beck, GR, Beers, MF, Begun, J, Behrends, C, Behrens, GMN, Bei, R, Bejarano, E, Bel, S, Behl, C, Belaid, A, Belgareh-Touzé, N, Bellarosa, C, Belleudi, F, Belló Pérez, M, Bello-Morales, R, Beltran, JSDO, Beltran, S, Benbrook, DM, Bendorius, M, Benitez, BA, Benito-Cuesta, I, Bensalem, J, Berchtold, MW, Berezowska, S, Bergamaschi, D, Bergami, M, Bergmann, A, Berliocchi, L, Berlioz-Torrent, C, Bernard, A, Berthoux, L, Besirli, CG, Besteiro, S, Betin, VM, Beyaert, R, Bezbradica, JS, Bhaskar, K, Bhatia-Kissova, I, Bhattacharya, R, Bhattacharya, S, Bhattacharyya, S, Bhuiyan, MS, Bhutia, SK, Bi, L, Bi, X, Biden, TJ, Bijian, K, Billes, VA, Binart, N, Bincoletto, C, Birgisdottir, AB, Bjorkoy, G, Blanco, G, Blas-Garcia, A, Blasiak, J, Blomgran, R, Blomgren, K, Blum, JS, Boada-Romero, E, Boban, M, Boesze-Battaglia, K, Boeuf, P, Boland, B, Bomont, P, Bonaldo, P, Bonam, SR, Bonfili, L, Bonifacino, JS, Boone, BA, Bootman, MD, Bordi, M, Borner, C, Bornhauser, BC, Borthakur, G, Bosch, J, Bose, S, Botana, LM, Botas, J, Boulanger, CM, Boulton, ME, Bourdenx, M, Bourgeois, B, Bourke, NM, Bousquet, G, Boya, P, Bozhkov, PV, Bozi, LHM, Bozkurt, TO, Brackney, DE, Brandts, CH, Braun, RJ, Braus, GH, Bravo-Sagua, R, Bravo-San Pedro, JM, Brest, P, Bringer, M-A, Briones-Herrera, A, Broaddus, VC, Brodersen, P, Brodsky, JL, Brody, SL, Bronson, PG, Bronstein, JM, Brown, CN, Brown, RE, Brum, PC, Brumell, JH, Brunetti-Pierri, N, Bruno, D, Bryson-Richardson, RJ, Bucci, C, Buchrieser, C, Bueno, M, Buitrago-Molina, LE, Buraschi, S, Buch, S, Buchan, JR, Buckingham, EM, Budak, H, Budini, M, Bultynck, G, Burada, F, Burgoyne, JR, Burón, MI, Bustos, V, Büttner, S, Butturini, E, Byrd, A, Cabas, I, Cabrera-Benitez, S, Cadwell, K, Cai, J, Cai, L, Cai, Q, Cairó, M, Calbet, JA, Caldwell, GA, Caldwell, KA, Call, JA, Calvani, R, Calvo, AC, Calvo-Rubio Barrera, M, Camara, NO, Camonis, JH, Camougrand, N, Campanella, M, Campbell, EM, Campbell-Valois, F-X, Campello, S, Campesi, I, Campos, JC, Camuzard, O, Cancino, J, Candido de Almeida, D, Canesi, L, Caniggia, I, Canonico, B, Cantí, C, Cao, B, Caraglia, M, Caramés, B, Carchman, EH, Cardenal-Muñoz, E, Cardenas, C, Cardenas, L, Cardoso, SM, Carew, JS, Carle, GF, Carleton, G, Carloni, S, Carmona-Gutierrez, D, Carneiro, LA, Carnevali, O, Carosi, JM, Carra, S, Carrier, A, Carrier, L, Carroll, B, Carter, AB, Carvalho, AN, Casanova, M, Casas, C, Casas, J, Cassioli, C, Castillo, EF, Castillo, K, Castillo-Lluva, S, Castoldi, F, Castori, M, Castro, AF, Castro-Caldas, M, Castro-Hernandez, J, Castro-Obregon, S, Catz, SD, Cavadas, C, Cavaliere, F, Cavallini, G, Cavinato, M, Cayuela, ML, Cebollada Rica, P, Cecarini, V, Cecconi, F, Cechowska-Pasko, M, Cenci, S, Ceperuelo-Mallafré, V, Cerqueira, JJ, Cerutti, JM, Cervia, D, Cetintas, VB, Cetrullo, S, Chae, H-J, Chagin, AS, Chai, C-Y, Chakrabarti, G, Chakrabarti, O, Chakraborty, T, Chami, M, Chamilos, G, Chan, DW, Chan, EYW, Chan, ED, Chan, HYE, Chan, HH, Chan, H, Chan, MTV, Chan, YS, Chandra, PK, Chang, C-P, Chang, C, Chang, H-C, Chang, K, Chao, J, Chapman, T, Charlet-Berguerand, N, Chatterjee, S, Chaube, SK, Chaudhary, A, Chauhan, S, Chaum, E, Checler, F, Cheetham, ME, Chen, C-S, Chen, G-C, Chen, J-F, Chen, LL, Chen, L, Chen, M, Chen, M-K, Chen, N, Chen, Q, Chen, R-H, Chen, S, Chen, W, Chen, X-M, Chen, X-W, Chen, X, Chen, Y, Chen, Y-G, Chen, Y-J, Chen, Y-Q, Chen, ZS, Chen, Z, Chen, Z-H, Chen, ZJ, Cheng, H, Cheng, J, Cheng, S-Y, Cheng, W, Cheng, X, Cheng, X-T, Cheng, Y, Cheng, Z, Cheong, H, Cheong, JK, Chernyak, BV, Cherry, S, Cheung, CFR, Cheung, CHA, Cheung, K-H, Chevet, E, Chi, RJ, Chiang, AKS, Chiaradonna, F, Chiarelli, R, Chiariello, M, Chica, N, Chiocca, S, Chiong, M, Chiou, S-H, Chiramel, AI, Chiurchiù, V, Cho, D-H, Choe, S-K, Choi, AMK, Choi, ME, Choudhury, KR, Chow, NS, Chu, CT, Chua, JP, Chua, JJE, Chung, H, Chung, KP, Chung, S, Chung, S-H, Chung, Y-L, Cianfanelli, V, Ciechomska, IA, Cifuentes, M, Cinque, L, Cirak, S, Cirone, M, Clague, MJ, Clarke, R, Clementi, E, Coccia, EM, Codogno, P, Cohen, E, Cohen, MM, Colasanti, T, Colasuonno, F, Colbert, RA, Colell, A, Čolić, M, Coll, NS, Collins, MO, Colombo, MI, Colón-Ramos, DA, Combaret, L, Comincini, S, Cominetti, MR, Consiglio, A, Conte, A, Conti, F, Contu, VR, Cookson, MR, Coombs, KM, Coppens, I, Corasaniti, MT, Corkery, DP, Cordes, N, Cortese, K, Costa, MDC, Costantino, S, Costelli, P, Coto-Montes, A, Crack, PJ, Crespo, JL, Criollo, A, Crippa, V, Cristofani, R, Csizmadia, T, Cuadrado, A, Cui, B, Cui, J, Cui, Y, Culetto, E, Cumino, AC, Cybulsky, AV, Czaja, MJ, Czuczwar, SJ, D'Adamo, S, D'Amelio, M, D'Arcangelo, D, D'Lugos, AC, D'Orazi, G, da Silva, JA, Dafsari, HS, Dagda, RK, Dagdas, Y, Daglia, M, Dai, X, Dai, Y, Dal Col, J, Dalhaimer, P, Dalla Valle, L, Dallenga, T, Dalmasso, G, Damme, M, Dando, I, Dantuma, NP, Darling, AL, Das, H, Dasarathy, S, Dasari, SK, Dash, S, Daumke, O, Dauphinee, AN, Davies, JS, Dávila, VA, Davis, RJ, Davis, T, Dayalan Naidu, S, De Amicis, F, De Bosscher, K, De Felice, F, De Franceschi, L, De Leonibus, C, de Mattos Barbosa, MG, De Meyer, GRY, De Milito, A, De Nunzio, C, De Palma, C, De Santi, M, De Virgilio, C, De Zio, D, Debnath, J, DeBosch, BJ, Decuypere, J-P, Deehan, MA, Deflorian, G, DeGregori, J, Dehay, B, Del Rio, G, Delaney, JR, Delbridge, LMD, Delorme-Axford, E, Delpino, MV, Demarchi, F, Dembitz, V, Demers, ND, Deng, H, Deng, Z, Dengjel, J, Dent, P, Denton, D, DePamphilis, ML, Der, CJ, Deretic, V, Descoteaux, A, Devis, L, Devkota, S, Devuyst, O, Dewson, G, Dharmasivam, M, Dhiman, R, di Bernardo, D, Di Cristina, M, Di Domenico, F, Di Fazio, P, Di Fonzo, A, Di Guardo, G, Di Guglielmo, GM, Di Leo, L, Di Malta, C, Di Nardo, A, Di Rienzo, M, Di Sano, F, Diallinas, G, Diao, J, Diaz-Araya, G, Díaz-Laviada, I, Dickinson, JM, Diederich, M, Dieudé, M, Dikic, I, Ding, S, Ding, W-X, Dini, L, Dinić, J, Dinic, M, Dinkova-Kostova, AT, Dionne, MS, Distler, JHW, Diwan, A, Dixon, IMC, 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- Abstract
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field.
- Published
- 2021
41. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
- Author
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Quadrilatero J., Walker D.W., Walker M.J., Walker S.A., Walter J., Wandosell F.G., Wang B., Wang C., Wang C.-Y., Wang D., Wang F., Wang G., Wang H., Wang H.-G., Wang J., Wang K., Wang L., Wang M.H., Wang M., Wang N., Wang P., Wang Q.J., Wang Q., Wang Q.K., Wang Q.A., Wang W.-T., Wang W., Wang X., Wang Y.-Y., Wang Y., Wang Z., Warnes G., Warnsmann V., Watada H., Watanabe E., Watchon M., Wawrzynska A., Weaver T.E., Wegrzyn G., Wehman A.M., Wei H., Wei L., Wei T., Wei Y., Weiergraber O.H., Weihl C.C., Weindl G., Weiskirchen R., Wells A., Wen R.H., Wen X., Werner A., Weykopf B., Wheatley S.P., W... [Ovid has truncated this field to avoid Excel character limitations], Klionsky D.J., Abdel-Aziz A.K., Abdelfatah S., Abdellatif M., Abdoli A., Abel S., Abeliovich H., Abildgaard M.H., Abudu Y.P., Acevedo-Arozena A., Adamopoulos I.E., Adeli K., Adolph T.E., Adornetto A., Aflaki E., Agam G., Agarwal A., Aggarwal B.B., Agnello M., Agostinis P., Agrewala J.N., Agrotis A., Aguilar P.V., Ahmad S.T., Ahmed Z.M., Ahumada-Castro U., Aits S., Aizawa S., Akkoc Y., Akoumianaki T., Akpinar H.A., Al-Abd A.M., Al-Akra L., Al-Gharaibeh A., Alaoui-Jamali M.A., Alberti S., Alcocer-Gomez E., Alessandri C., Ali M., Alim Al-Bari M.A., Aliwaini S., Alizadeh J., Almacellas E., Almasan A., Alonso A., Alonso G.D., Altan-Bonnet N., Altieri D.C., Alvarez E.M.C., Alves S., Alves da Costa C., Alzaharna M.M., Amadio M., Amantini C., Amaral C., Ambrosio S., Amer A.O., Ammanathan V., An Z., Andersen S.U., Andrabi S.A., Andrade-Silva M., Andres A.M., Angelini S., Ann D., Anozie U.C., Ansari M.Y., Antas P., Antebi A., Anton Z., Anwar T., Apetoh L., Apostolova N., Araki T., Araki Y., Arasaki K., Araujo W.L., Araya J., Arden C., Arevalo M.-A., Arguelles S., Arias E., Arikkath J., Arimoto H., Ariosa A.R., Armstrong-James D., Arnaune-Pelloquin L., Aroca A., Arroyo D.S., Arsov I., Artero R., Asaro D.M.L., Aschner M., Ashrafizadeh M., Ashur-Fabian O., Atanasov A.G., Au A.K., Auberger P., Auner H.W., Aurelian L., Autelli R., Avagliano L., Avalos Y., Aveic S., Aveleira C.A., Avin-Wittenberg T., Aydin Y., Ayton S., Ayyadevara S., Azzopardi M., Baba M., Backer J.M., Backues S.K., Bae D.-H., Bae O.-N., Bae S.H., Baehrecke E.H., Baek A., Baek S.-H., Baek S.H., Bagetta G., Bagniewska-Zadworna A., Bai H., Bai J., Bai X., Bai Y., Bairagi N., Baksi S., Balbi T., Baldari C.T., Balduini W., Ballabio A., Ballester M., Balazadeh S., Balzan R., Bandopadhyay R., Banerjee S., Banreti A., Bao Y., Baptista M.S., Baracca A., Barbati C., Bargiela A., Barila D., Barlow P.G., Barmada S.J., Barreiro E., Barreto G.E., Bartek J., Bartel B., Bartolome A., Barve G.R., Basagoudanavar S.H., Bassham D.C., Bast R.C., Basu A., Batoko H., Batten I., Baulieu E.E., Baumgarner B.L., Bayry J., Beale R., Beau I., Beaumatin F., Bechara L.R.G., Beck G.R., Beers M.F., Begun J., Behrends C., Behrens G.M.N., Bei R., Bejarano E., Bel S., Behl C., Belaid A., Belgareh-Touze N., Bellarosa C., Belleudi F., Bello Perez M., Bello-Morales R., Beltran J.S.D.O., Beltran S., Benbrook D.M., Bendorius M., Benitez B.A., Benito-Cuesta I., Bensalem J., Berchtold M.W., Berezowska S., Bergamaschi D., Bergami M., Bergmann A., Berliocchi L., Berlioz-Torrent C., Bernard A., Berthoux L., Besirli C.G., Besteiro S., Betin V.M., Beyaert R., Bezbradica J.S., Bhaskar K., Bhatia-Kissova I., Bhattacharya R., Bhattacharya S., Bhattacharyya S., Bhuiyan M.S., Bhutia S.K., Bi L., Bi X., Biden T.J., Bijian K., Billes V.A., Binart N., Bincoletto C., Birgisdottir A.B., Bjorkoy G., Blanco G., Blas-Garcia A., Blasiak J., Blomgran R., Blomgren K., Blum J.S., Boada-Romero E., Boban M., Boesze-Battaglia K., Boeuf P., Boland B., Bomont P., Bonaldo P., Bonam S.R., Bonfili L., Bonifacino J.S., Boone B.A., Bootman M.D., Bordi M., Borner C., Bornhauser B.C., Borthakur G., Bosch J., Bose S., Botana L.M., Botas J., Boulanger C.M., Boulton M.E., Bourdenx M., Bourgeois B., Bourke N.M., Bousquet G., Boya P., Bozhkov P.V., Bozi L.H.M., Bozkurt T.O., Brackney D.E., Brandts C.H., Braun R.J., Braus G.H., Bravo-Sagua R., Bravo-San Pedro J.M., Brest P., Bringer M.-A., Briones-Herrera A., Broaddus V.C., Brodersen P., Brodsky J.L., Brody S.L., Bronson P.G., Bronstein J.M., Brown C.N., Brown R.E., Brum P.C., Brumell J.H., Brunetti-Pierri N., Bruno D., Bryson-Richardson R.J., Bucci C., Buchrieser C., Bueno M., Buitrago-Molina L.E., Buraschi S., Buch S., Buchan J.R., Buckingham E.M., Budak H., Budini M., Bultynck G., Burada F., Burgoyne J.R., Buron M.I., Bustos V., Buttner S., Butturini E., Byrd A., Cabas I., Cabrera-Benitez S., Cadwell K., Cai J., Cai L., Cai Q., Cairo M., Calbet J.A., Caldwell G.A., Caldwell K.A., Call J.A., Calvani R., Calvo A.C., Calvo-Rubio Barrera M., Camara N.O.S., Camonis J.H., Camougrand N., Campanella M., Campbell E.M., Campbell-Valois F.-X., Campello S., Campesi I., Campos J.C., Camuzard O., Cancino J., Candido de Almeida D., Canesi L., Caniggia I., Canonico B., Canti C., Cao B., Caraglia M., Carames B., Carchman E.H., Cardenal-Munoz E., Cardenas C., Cardenas L., Cardoso S.M., Carew J.S., Carle G.F., Carleton G., Carloni S., Carmona-Gutierrez D., Carneiro L.A., Carnevali O., Carosi J.M., Carra S., Carrier A., Carrier L., Carroll B., Carter A.B., Carvalho A.N., Casanova M., Casas C., Casas J., Cassioli C., Castillo E.F., Castillo K., Castillo-Lluva S., Castoldi F., Castori M., Castro A.F., Castro-Caldas M., Castro-Hernandez J., Castro-Obregon S., Catz S.D., Cavadas C., Cavaliere F., Cavallini G., Cavinato M., Cayuela M.L., Cebollada Rica P., Cecarini V., Cecconi F., Cechowska-Pasko M., Cenci S., Ceperuelo-Mallafre 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[Ovid has truncated this field to avoid Excel character limitations], Klionsky D.J., Abdel-Aziz A.K., Abdelfatah S., Abdellatif M., Abdoli A., Abel S., Abeliovich H., Abildgaard M.H., Abudu Y.P., Acevedo-Arozena A., Adamopoulos I.E., Adeli K., Adolph T.E., Adornetto A., Aflaki E., Agam G., Agarwal A., Aggarwal B.B., Agnello M., Agostinis P., Agrewala J.N., Agrotis A., Aguilar P.V., Ahmad S.T., Ahmed Z.M., Ahumada-Castro U., Aits S., Aizawa S., Akkoc Y., Akoumianaki T., Akpinar H.A., Al-Abd A.M., Al-Akra L., Al-Gharaibeh A., Alaoui-Jamali M.A., Alberti S., Alcocer-Gomez E., Alessandri C., Ali M., Alim Al-Bari M.A., Aliwaini S., Alizadeh J., Almacellas E., Almasan A., Alonso A., Alonso G.D., Altan-Bonnet N., Altieri D.C., Alvarez E.M.C., Alves S., Alves da Costa C., Alzaharna M.M., Amadio M., Amantini C., Amaral C., Ambrosio S., Amer A.O., Ammanathan V., An Z., Andersen S.U., Andrabi S.A., Andrade-Silva M., Andres A.M., Angelini S., Ann D., Anozie U.C., Ansari M.Y., Antas P., Antebi A., 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Viret C., Viscomi M.T., Visnjic D., Vitale I., Vocadlo D.J., Voitsekhovskaja O.V., Volonte C., Volta M., Vomero M., Von Haefen C., Vooijs M.A., Voos W., Vucicevic L., Wade-Martins R., Waguri S., Waite K.A., and Wakatsuki S.
- Abstract
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field.Copyright © 2020 Informa UK Limited, trading as Taylor & Francis Group.
- Published
- 2021
42. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
- Author
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[Ovid has truncated this field to avoid Excel character limitations], Klionsky D.J., Abdel-Aziz A.K., Abdelfatah S., Abdellatif M., Abdoli A., Abel S., Abeliovich H., Abildgaard M.H., Abudu Y.P., Acevedo-Arozena A., Adamopoulos I.E., Adeli K., Adolph T.E., Adornetto A., Aflaki E., Agam G., Agarwal A., Aggarwal B.B., Agnello M., Agostinis P., Agrewala J.N., Agrotis A., Aguilar P.V., Ahmad S.T., Ahmed Z.M., Ahumada-Castro U., Aits S., Aizawa S., Akkoc Y., Akoumianaki T., Akpinar H.A., Al-Abd A.M., Al-Akra L., Al-Gharaibeh A., Alaoui-Jamali M.A., Alberti S., Alcocer-Gomez E., Alessandri C., Ali M., Alim Al-Bari M.A., Aliwaini S., Alizadeh J., Almacellas E., Almasan A., Alonso A., Alonso G.D., Altan-Bonnet N., Altieri D.C., Alvarez E.M.C., Alves S., Alves da Costa C., Alzaharna M.M., Amadio M., Amantini C., Amaral C., Ambrosio S., Amer A.O., Ammanathan V., An Z., Andersen S.U., Andrabi S.A., Andrade-Silva M., Andres A.M., Angelini S., Ann D., Anozie U.C., Ansari M.Y., Antas P., Antebi A., 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[Ovid has truncated this field to avoid Excel character limitations]
- Abstract
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field.Copyright © 2020 Informa UK Limited, trading as Taylor & Francis Group.
- Published
- 2021
43. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
- Author
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Werner, Brand-Saberi, Beate, Dong, X Charlie, Kenchappa, Chandra Shekar, Li, Zuguo, Lin, Yong, Oshima, Shigeru, Rong, Yueguang, Sluimer, Judith C, Stallings, Christina L, and Tong, Chun-Kit
- Abstract
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field.
- Published
- 2021
44. REM sleep behavior disorder and sleep-related eplepsy: P478
- Author
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Nozawa, T.
- Published
- 2014
45. Shear properties at the PyC/SiC interface of a TRISO-coating
- Author
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Nozawa, T., Snead, L.L., Katoh, Y., and Miller, J.H.
- Published
- 2007
- Full Text
- View/download PDF
46. Effect of neutron irradiation on tensile properties of unidirectional silicon carbide composites
- Author
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Katoh, Y., Nozawa, T., Snead, L.L., and Hinoki, T.
- Published
- 2007
- Full Text
- View/download PDF
47. Mechanical properties of advanced SiC/SiC composites after neutron irradiation
- Author
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Ozawa, K., Nozawa, T., Katoh, Y., Hinoki, T., and Kohyama, A.
- Published
- 2007
- Full Text
- View/download PDF
48. The effects of neutron irradiation on shear properties of monolayered PyC and multilayered PyC/SiC interfaces of SiC/SiC composites
- Author
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Nozawa, T., Katoh, Y., and Snead, L.L.
- Published
- 2007
- Full Text
- View/download PDF
49. Conceptual design progress of advanced fusion neutron source
- Author
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Ochiai, K., primary, Sato, S., additional, Kondo, H., additional, Ohta, M., additional, Oyaidzu, M., additional, Nakamura, M.M., additional, Kwon, S., additional, Tanigawa, H., additional, Nozawa, T., additional, Kasugai, A., additional, Sakamoto, K., additional, and Ishida, S., additional
- Published
- 2020
- Full Text
- View/download PDF
50. Optimizing the Fabrication Process for Excellent Mechanical Properties in Stoichiometric SiC Fiber/FCVI SiC Matrix Composites
- Author
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Taguchi, T., primary, Igawa, N., additional, Jitsukawa, S., additional, Snead, L. L., additional, McLaughlin, J. C., additional, Nozawa, T., additional, Katoh, Y., additional, and Kohyama, A., additional
- Published
- 2012
- Full Text
- View/download PDF
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