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1,271 results on '"Nozaki Y."'

1. Temporal-offset dual-comb vibrometer with picometer axial precision

Author

Iwasaki, A., Nishikawa, D., Okano, M., Tateno, S., Yamanoi, K., Nozaki, Y., and Watanabe, S.

Subjects
Physics - Optics, Condensed Matter - Materials Science, Physics - Instrumentation and Detectors
Abstract

We demonstrate a dual-comb vibrometer where the pulses of one frequency-comb are split into pulse pairs. We introduce a delay between the two pulses of each pulse pair in front of the sample, and after the corresponding two consecutive reflections at the vibrating sample surface, the initially introduced delay is cancelled by a modified Sagnac geometry. The remaining phase difference between the two pulses corresponds to the change in the axial position of the surface during the two consecutive reflections. The Sagnac geometry reduces the effect of phase jitter since both pulses propagate through nearly the same optical path (in opposite directions), and spurious signals are eliminated by time gating. We determine the amplitude of a surface vibration on a surface-acoustic-wave device with an axial precision of 4 pm. This technique enables highly accurate determination of extremely small displacements., Comment: 22 pages, 5 figures

Published
2022
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2. Homotopy classification of knotted defects in ordered media.

Author

Nozaki, Y., Kálmán, T., Teragaito, M., and Koda, Y.

Subjects
*NEMATIC liquid crystals, *CONJUGACY classes, *LIQUID crystals, *SUPERFLUIDITY, *QUATERNIONS, *HOMOTOPY groups
Abstract

We give a homotopy classification of the global defects in ordered media and explain it via the example of biaxial nematic liquid crystals, that is, systems where the order parameter space is the quotient of the three-sphere S3 by the quaternion group Q. As our mathematical model, we consider continuous maps from complements of spatial graphs to the space S3/Q modulo a certain equivalence relation and find that the equivalence classes are enumerated by the six subgroups of Q. Through monodromy around meridional loops, the edges of our spatial graphs are marked by conjugacy classes of Q ; once we pass to planar diagrams, these labels can be refined to elements of Q associated with each arc. The same classification scheme applies not only in the case of Q but also to arbitrary groups. [ABSTRACT FROM AUTHOR]

Published
2024
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3. Diagnostic Accuracy of Diastolic Fractional Flow Reserve for Functional Evaluation of Coronary Stenosis: DIASTOLE Study

Author

Shiono, Y., Katayama, Y., Hironori, K., Kubo, T., Akasaka, T., Tanaka, N., Yamashita, J., Fujita, H., Matsuo, A., Matsuo, H., Kawase, Y., Kawamura, I., Kakuta, T., Hoshino, M., Sugano, T., Takashima, H., Amano, T., Yokoi, H., Yamamoto, Y., Nozaki, Y., Machida, M., Kobori, M., Kikuchi, T., Ohira, H., Yoshino, H., Ishiguro, H., Wakabayashi, Y., Kondo, T., Terai, H., Suwa, T., Kimura, T., Kawajiri, T., Hirohata, A., Uemura, S., Neishi, Y., Sakamoto, T., Yamada, M., Okeie, K., Hishikari, K., Oguri, M., Uetani, T., Saegusa, T., Yamamoto, F., Shiono, Yasutsugu, Matsuo, Hitoshi, Fujita, Hiroshi, Tanaka, Nobuhiro, Ogasawara, Yasuo, Kawamura, Itta, Katayama, Yosuke, Matsuo, Akiko, Kawase, Yoshiaki, Kakuta, Tsunekazu, Takashima, Hiroaki, Yokoi, Hiroyoshi, Ohira, Hiroshi, Suwa, Satoru, Oguri, Mitsutoshi, Yamamoto, Fumi, Kubo, Takashi, and Akasaka, Takashi

Published
2021
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4. Infliximab dose adjustment can improve the clinical and radiographic outcomes of rheumatoid arthritis patients: REVIVE study results

Author

Nozaki Y, Nagare Y, Ashida C, Tomita D, Okada A, Inoue A, Kinoshita K, Funauchi M, and Matsumura I

Subjects
rheumatoid arthritis, DAS28, infliximab, mTSS, dose adjustment, REVIVE, Medicine (General), R5-920
Abstract

Yuji Nozaki, Yasuaki Nagare, Chisato Ashida, Daisuke Tomita, Akinori Okada, Asuka Inoue, Koji Kinoshita, Masanori Funauchi, Itaru Matsumura Department of Hematology and Rheumatology, Kindai University School of Medicine, Osaka, Japan Purpose: We evaluated the clinical responses and radiographic outcomes of 90 patients with rheumatoid arthritis (RA) undergoing continuous or dose-adjusted infliximab treatment over 104 weeks.Patients and methods: Patients received 3 mg/kg infliximab continuously (the contin group; n=50), or the dose escalation and de-escalation of infliximab (3, 6, and 10 mg/kg) from week 14 (the adjusted group; n=40) based on the patient’s Disease Activity Score in 28 joints (DAS28). The retention rate, clinical response, and radiographic assessment were determined at week 104.Results: The contin and adjusted groups’ retention rates at week 104 were 56.8 and 66.7%, and the groups’ low disease activity in the DAS28 was 39.1 and 66.7%, respectively. Remission based on the DAS28 and the American College of Rheumatology (ACR)/European League against Rheumatism (EULAR) Boolean-based criteria was significantly increased in the adjusted group. In the radiographic assessment, there was also a significant reduction in the mean changes in total Sharp score. The cumulative rates of any adverse effects showed no significant difference between the groups.Conclusion: In an assessment of adequate DAS28 results, the RA patients who did not respond to the initial dose of infliximab showed improved clinical responses and radiographic assessment after a dose adjustment of infliximab, without an increased risk of serious adverse events. Keywords: rheumatoid arthritis, DAS28, infliximab, mTSS, dose adjustment, REVIVE

Published
2018

13. Rivaroxaban Monotherapy in Patients With Atrial Fibrillation After Coronary Stenting

Author

Matoba, Tetsuya, primary, Yasuda, Satoshi, additional, Kaikita, Koichi, additional, Akao, Masaharu, additional, Ako, Junya, additional, Nakamura, Masato, additional, Miyauchi, Katsumi, additional, Hagiwara, Nobuhisa, additional, Kimura, Kazuo, additional, Hirayama, Atsushi, additional, Matsui, Kunihiko, additional, Ogawa, Hisao, additional, Matoba, Tetsuya, additional, Koretsune, Yukihiro, additional, Hiro, Takafumi, additional, Sumiyoshi, Tetsuya, additional, Kimura, Kazumi, additional, Hashimoto, Yoichiro, additional, Hirano, Teruyuki, additional, Daida, Hiroyuki, additional, Okada, Yasushi, additional, Yamazaki, Tsutomu, additional, Nakamura, A., additional, Tamiya, E., additional, Yamamoto, T., additional, Suetake, S., additional, Noguchi, T., additional, Nakamura, S., additional, Matsumura, A., additional, Kojima, J., additional, Suwa, S., additional, Yamaguchi, H., additional, Kaikita, K., additional, Yasu, T., additional, Nakajima, A., additional, Yamada, T., additional, Arai, H., additional, Hata, Y., additional, Sakanashi, T., additional, Tateishi, H., additional, Nakayama, T., additional, Nozaki, Y., additional, Akao, M., additional, Okumura, Y., additional, Tokue, M., additional, Kuroki, N., additional, Maruyama, Y., additional, Matoba, T., additional, Hagiwara, N., additional, Suzuki, H., additional, Nishida, Y., additional, Ajioka, M., additional, Yumoto, K., additional, Shimizu, S., additional, Aoyama, T., additional, Shimomura, H., additional, Takeda, T., additional, Oshiro, K., additional, Sugishita, N., additional, Shibata, Y., additional, Otonari, T., additional, Kihara, H., additional, Ogawa, H., additional, Ohno, A., additional, Hazama, M., additional, Shimizu, M., additional, Tsukahara, K., additional, Haruta, S., additional, Wakeyama, T., additional, Haruna, T., additional, Ito, M., additional, Fujii, K., additional, Atsuchi, N., additional, Sata, M., additional, Kimura, K., additional, Hasebe, N., additional, Kobayasi, Y., additional, Ohsato, K., additional, Hironaga, K., additional, Naganuma, Y., additional, Anzaki, K., additional, Oiwa, K., additional, Okazaki, S., additional, Nakagawa, Y., additional, Tokuhiro, K., additional, Tanaka, K., additional, Momose, T., additional, Fukushima, Y., additional, Kametani, R., additional, Kawamitsu, K., additional, Saito, Y., additional, Akashi, S., additional, Kumagai, K., additional, Eshima, K., additional, Tobaru, T., additional, Seo, T., additional, Okuhara, K., additional, Kozuma, K., additional, Ikari, Y., additional, Takahashi, T., additional, Michishita, I., additional, Fujikura, H., additional, Momomura, S., additional, Yamamoto, Y., additional, Otomo, K., additional, Matsubara, T., additional, Tashiro, H., additional, Inoue, T., additional, Ishihara, M., additional, Shiojima, I., additional, Tachibana, E., additional, Ako, J., additional, Sumii, K., additional, Yamamoto, N., additional, Ohmura, N., additional, Nakamura, T., additional, Morita, Y., additional, Takahashi, N., additional, Watanabe, K., additional, Fujinaga, H., additional, Maruyama, M., additional, Oka, T., additional, Shirayama, T., additional, Amano, T., additional, Fukui, K., additional, Ando, K., additional, Oshima, S., additional, Kagiyama, S., additional, Teragawa, H., additional, Yuge, M., additional, Ono, S., additional, Koga, T., additional, Fujiu, K., additional, Kuwabara, M., additional, Ohya, Y., additional, Yumoto, Y., additional, Kuji, N., additional, Ikemura, M., additional, Kario, K., additional, Chatani, K., additional, Sato, K., additional, Miyagi, H., additional, Murakami, M., additional, Saito, K., additional, Hoshiga, M., additional, Sato, S., additional, Kubo, N., additional, Sakamoto, Y., additional, Ashida, K., additional, Sakamoto, H., additional, Murasaki, S., additional, Uehara, H., additional, Akasaka, T., additional, Ooba, Y., additional, Nakahara, S., additional, Hanaoka, Y., additional, Nishimiya, T., additional, Tsunoda, R., additional, Onuma, Y., additional, Higuchi, S., additional, Tani, A., additional, Wada, A., additional, Kato, M., additional, Obata, H., additional, Higuchi, Y., additional, Endo, T., additional, Katou, R., additional, Matsunaga, T., additional, Matsuoka, T., additional, Noguchi, H., additional, Usui, M., additional, Hayashi, T., additional, Otsuji, Y., additional, Osaki, T., additional, Zaizen, H., additional, Yoshihara, H., additional, Kadota, K., additional, Hirose, T., additional, Miyazawa, T., additional, Mori, A., additional, Takano, M., additional, Shimizu, W., additional, Wake, M., additional, Oriso, S., additional, Yoshiyama, M., additional, Kakinoki, S., additional, Nishioka, T., additional, Ozaki, T., additional, Nomoto, K., additional, Seki, K., additional, Kawai, K., additional, Ozaki, Y., additional, Miura, S., additional, Kawasaki, M., additional, Funada, R., additional, Dote, K., additional, Nagano, T., additional, Okamoto, S., additional, Kubo, T., additional, Murozono, Y., additional, Owada, T., additional, Doke, T., additional, Matsumura, T., additional, Horiuchi, M., additional, Takaishi, A., additional, Yamamoto, M., additional, Nakashima, H., additional, Munemasa, M., additional, Sakata, Y., additional, Inoue, N., additional, Ota, T., additional, Hamano, Y., additional, Abe, N., additional, Tsubokura, T., additional, Goto, M., additional, Kubota, I., additional, Yano, M., additional, Umetani, K., additional, Date, T., additional, Morimoto, H., additional, Noda, T., additional, Goto, S., additional, Hibi, K., additional, Nakano, A., additional, Hiramitsu, S., additional, Kihara, Y., additional, Sugi, M., additional, Shiba, N., additional, Izumi, D., additional, Sato, T., additional, Tayama, S., additional, Matsui, T., additional, Suzuki, A., additional, Ajiki, K., additional, Oishi, M., additional, Kiryu, M., additional, Ko, T., additional, Ando, H., additional, Miyazaki, S., additional, Kinugawa, T., additional, Otake, H., additional, Kitaoka, H., additional, Hirata, Y., additional, Honda, S., additional, Manita, M., additional, Ishii, Y., additional, Oka, H., additional, Nanba, Y., additional, Nishino, M., additional, Sakamoto, T., additional, Saito, T., additional, Sakai, H., additional, Ichikawa, M., additional, Namiuchi, S., additional, Inoue, K., additional, Komiyama, N., additional, Akashi, Y., additional, Nakamura, Y., additional, Komaru, T., additional, Hosokawa, T., additional, Chikamori, T., additional, Tanaka, H., additional, Arasaki, O., additional, Aonuma, K., additional, Wakasa, Y., additional, Yoshizawa, T., additional, Sugano, T., additional, Yokota, N., additional, Kakutani, A., additional, Suzuki, T., additional, Abe, Y., additional, Kataoka, T., additional, Okayama, H., additional, Yokoi, H., additional, Chin, K., additional, Hasegawa, K., additional, Tomita, H., additional, Honzyo, H., additional, Kawai, H., additional, Yamamoto, K., additional, Morino, Y., additional, Tsujiyama, S., additional, Hamasaki, S., additional, Niijima, Y., additional, Mizuno, Y., additional, Maki, A., additional, Tanabe, K., additional, Murohara, T., additional, Naomi, S., additional, Arikawa, M., additional, Kato, T., additional, Matsumoto, N., additional, Minamino, T., additional, Sairenji, H., additional, Miyamoto, N., additional, Ito, H., additional, Matsuura, Y., additional, Hata, S., additional, Nakatsu, Y., additional, Onodera, T., additional, Yoshimura, M., additional, Amano, H., additional, Tokutake, E., additional, Kasao, M., additional, Moriguchi, M., additional, Tsuji, M., additional, Yamamoto, H., additional, Yanbe, Y., additional, Iwasawa, T., additional, Suzuki, M., additional, and Mori, H., additional

Published
2021
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21. Involvement of JNK pathway in the promotion of the early stage of colorectal carcinogenesis under high-fat dietary conditions

Author

Endo, H., Hosono, K., Fujisawa, T., Takahashi, H., Sugiyama, M., Yoneda, K., Nozaki, Y., Fujita, K., Yoneda, M., Inamori, M., Wada, K., Nakagama, H., and Nakajima, A.

Subjects
Colorectal cancer -- Development and progression, Colorectal cancer -- Models, Colorectal cancer -- Research, c-Jun N-terminal kinases -- Physiological aspects, c-Jun N-terminal kinases -- Research, Dietary fat -- Health aspects, Dietary fat -- Research, Health
Published
2009

22. Effectiveness of antiplatelet drugs against experimental non-alcoholic fatty liver disease

Author

Fujita, K., Nozaki, Y., Wada, K., Yoneda, M., Endo, H., Takahashi, H., Iwasaki, T., Inamori, M., Abe, Y., Kobayashi, N., Kirikoshi, H., Kubota, K., Saito, S., Nagashima, Y., and Nakajima, A.

Subjects
Fatty liver -- Drug therapy, Fatty liver -- Research, Blood platelets -- Aggregation, Blood platelets -- Dosage and administration, Blood platelets -- Research, Health
Published
2008

26. Surface temperature effects on hydrogen and impurity release from the limiter studied by means of visible and near infrared spectroscopic measurement in TRIAM-1M

Author

Bhattacharyay, R., Zushi, H., Nakashima, K., Shikama, T., Sakamoto, M., Ogawa, M., Nakamura, K., Yoshida, N., Kado, S., Sawada, K., Hirooka, Y., Hanada, K., Sato, K.N., Idei, H., Sasaki, K., Xu, H., Hasegawa, M., Uehara, K., Tsushima, A., Kimura, N., Nozaki, Y., Kawasaki, S., Nakashima, H., and Higashijima, A.

Published
2007
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28. Numerical study for ballistic switching of magnetization in single domain particle triggered by a ferromagnetic resonance within a relaxation time limit

Author

Nozaki, Y. and Matsuyama, K.

Subjects
Magnetization -- Research, Numerical analysis, Physics
Abstract

Magnetization reversal through successive ballistic rotation caused by an application of alternative field temporally varying within a relaxation time limit is numerically investigated. As the Gilbert damping constant is smaller than 0.03, a pronounced beat appears in the temporal evolution of rotating angle of magnetization.

Published
2006

46. Excess hydrogen sulfide and polysulfides production underlies a schizophrenia pathophysiology

Author

Ide, M, Ohnishi, T, Toyoshima, M, Balan, S, Maekawa, M, Shimamoto-Mitsuyama, C, Iwayama, Y, Ohba, H, Watanabe, A, Ishii, T, Shibuya, N, Kimura, Y, Hisano, Y, Murata, Y, Hara, T, Morikawa, M, Hashimoto, K, Nozaki, Y, Toyota, T, Wada, Y, Tanaka, Y, Kato, T, Nishi, A, Fujisawa, S, Okano, H, Itokawa, M, Hirokawa, N, Kunii, Y, Kakita, A, Yabe, H, Iwamoto, K, Meno, K, Katagiri, T, Dean, B, Uchida, K, Kimura, H, Yoshikawa, T, Ide, M, Ohnishi, T, Toyoshima, M, Balan, S, Maekawa, M, Shimamoto-Mitsuyama, C, Iwayama, Y, Ohba, H, Watanabe, A, Ishii, T, Shibuya, N, Kimura, Y, Hisano, Y, Murata, Y, Hara, T, Morikawa, M, Hashimoto, K, Nozaki, Y, Toyota, T, Wada, Y, Tanaka, Y, Kato, T, Nishi, A, Fujisawa, S, Okano, H, Itokawa, M, Hirokawa, N, Kunii, Y, Kakita, A, Yabe, H, Iwamoto, K, Meno, K, Katagiri, T, Dean, B, Uchida, K, Kimura, H, and Yoshikawa, T

Abstract

Mice with the C3H background show greater behavioral propensity for schizophrenia, including lower prepulse inhibition (PPI), than C57BL/6 (B6) mice. To characterize as-yet-unknown pathophysiologies of schizophrenia, we undertook proteomics analysis of the brain in these strains, and detected elevated levels of Mpst, a hydrogen sulfide (H2 S)/polysulfide-producing enzyme, and greater sulfide deposition in C3H than B6 mice. Mpst-deficient mice exhibited improved PPI with reduced storage sulfide levels, while Mpst-transgenic (Tg) mice showed deteriorated PPI, suggesting that "sulfide stress" may be linked to PPI impairment. Analysis of human samples demonstrated that the H2 S/polysulfides production system is upregulated in schizophrenia. Mechanistically, the Mpst-Tg brain revealed dampened energy metabolism, while maternal immune activation model mice showed upregulation of genes for H2 S/polysulfides production along with typical antioxidative genes, partly via epigenetic modifications. These results suggest that inflammatory/oxidative insults in early brain development result in upregulated H2 S/polysulfides production as an antioxidative response, which in turn cause deficits in bioenergetic processes. Collectively, this study presents a novel aspect of the neurodevelopmental theory for schizophrenia, unraveling a role of excess H2 S/polysulfides production.

Published
2019

50. A new mutant rat with turning behaviour (Tur)

Author

Yamazaki, K., Mikami, T., Kawaguchi, A., Kuwabara, M., Nozaki, Y., Hosokawa, S., Tagaya, O., Katoh, H., Yamamoto, N., and Wakabayashi, T.

Subjects
Rats -- Behavior, Animal mutation -- Research, Biological sciences
Abstract

Circling or turning behavior in response to extroceptive stimuli is found in a new rat strain. Mutant conditions were created by crossing brothers and sisters of the species and the offspring exhibited the same behavior, creating the congenic strain, WKY/Eis-Tur. The study reveals that there is no abnormality in the cerebrum, cerebellum or posterior, lateral or anterior semicircular canals of the rat. The mutation is an autosomal dominant gene.

Published
1995

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