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Episodic future thinking (EFT), the ability to imagine future autobiographical events, is both an everyday and clinically significant cognitive process. With a focus on depression and suicidality, here we discuss evidence connecting EFT with psychopathology. Emotional valence of imagined future events has emerged as the most widely established feature of EFT detected to date, with less positive EFT being associated with depressive symptoms and suicidal thoughts and behaviors. This pattern may not be merely a byproduct of sadness or anhedonia. Promising directions for future research include clarifying the temporal association between EFT and clinical outcomes, investigating the potential benefits and drawbacks of positive EFT, and refining assessments for youth to measure EFT either preceding or soon after onset of psychopathology., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)