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17 results on '"Nouchi, Yuki"'

3. High-fructose corn syrup intake has stronger effects on the transcription level of hepatic lipid metabolism-related genes, via DNA methylation modification, in childhood and adolescence than in other generations

Author

Mizuno, Genki, Yamada, Hiroya, Munetsuna, Eiji, Ando, Yoshitaka, Teshigawara, Atsushi, Ito, Manaka, Kageyama, Itsuki, Nouchi, Yuki, Wakasugi, Takuya, Sakakibara, Tomohide, Yamazaki, Mirai, Fujii, Ryosuke, Ishikawa, Hiroaki, Suzuki, Koji, Hashimoto, Shuji, and Ohashi, Koji

Published
2022
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5. Low mitochondrial DNA copy number in peripheral blood mononuclear cells is associated with future mortality risk: a long-term follow-up study from Japan

Author

Mizuno, Genki, primary, Yamada, Hiroya, additional, Tsuboi, Yoshiki, additional, Munetsuna, Eiji, additional, Yamazaki, Mirai, additional, Ando, Yoshitaka, additional, Kageyama, Itsuki, additional, Nouchi, Yuki, additional, Teshigawara, Atsushi, additional, Hattori, Yuji, additional, Fujii, Ryosuke, additional, Ishikawa, Hiroaki, additional, Hashimoto, Shuji, additional, Ohashi, Koji, additional, Hamajima, Nobuyuki, additional, and Suzuki, Koji, additional

Published
2024
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6. Impact of maternal fructose intake on liver stem/progenitor cells in offspring: Insights into developmental origins of health and disease

Author

Ando, Yoshitaka, primary, Munetsuna, Eiji, additional, Yamada, Hiroya, additional, Ikeya, Miyuki, additional, Teshigawara, Atsushi, additional, Kageyama, Itsuki, additional, Nouchi, Yuki, additional, Wakasugi, Takuya, additional, Yamazaki, Mirai, additional, Mizuno, Genki, additional, Tsuboi, Yoshiki, additional, Ishikawa, Hiroaki, additional, Ohgami, Nobutaka, additional, Suzuki, Koji, additional, and Ohashi, Koji, additional

Published
2023
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7. Interaction between Prenatal and Postnatal Exposure to High-Fructose Corn Syrup Increases Gene Expression of Tnfa in Hippocampus of Offspring

Author

YAMAZAKI, Mirai, primary, YAMADA, Hiroya, additional, MUNETSUNA, Eiji, additional, ANDO, Yoshitaka, additional, KAGEYAMA, Itsuki, additional, SADAMOTO, Nao, additional, NOUCHI, Yuki, additional, TESHIGAWARA, Atsushi, additional, MIZUNO, Genki, additional, ISHIKAWA, Hiroaki, additional, SUZUKI, Koji, additional, HASHIMOTO, Shuji, additional, and OHASHI, Koji, additional

Published
2023
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8. Laboratory analysis of glucose|fructose|and sucrose contents in Japanese common beverages for the exact assessment of beverage-derived sugar intake

Author

Ando, Yoshitaka, Ohta, Yoshiji, Munetsuna, Eiji, Yamada, Hiroya, Nouchi, Yuki, Kageyama, Itsuki, Mizuno, Genki, Yamazaki, Mirai, Fujii, Ryosuke, Ishikawa, Hiroaki, Suzuki, Koji, Hashimoto, Shuji, Ohashi, Koji, Ando, Yoshitaka, Ohta, Yoshiji, Munetsuna, Eiji, Yamada, Hiroya, Nouchi, Yuki, Kageyama, Itsuki, Mizuno, Genki, Yamazaki, Mirai, Fujii, Ryosuke, Ishikawa, Hiroaki, Suzuki, Koji, Hashimoto, Shuji, and Ohashi, Koji

Published
2023

9. High-fructose corn syrup intake increases hepatic mitochondrial DNA copy number and methylation in adolescent rats

Author

Mizuno, Genki, primary, Yamada, Hiroya, additional, Munetsuna, Eiji, additional, Ando, Yoshitaka, additional, Teshigawara, Atsushi, additional, Ito, Manaka, additional, Kageyama, Itsuki, additional, Nouchi, Yuki, additional, Wakasugi, Takuya, additional, Sakakibara, Tomohide, additional, Yamazaki, Mirai, additional, Ishikawa, Hiroaki, additional, Suzuki, Koji, additional, Hashimoto, Shuji, additional, and Ohashi, Koji, additional

Published
2023
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10. Effects of High-Fructose Corn Syrup Intake on Glucocorticoid Metabolism in Rats During Childhood, Adolescence and Adulthood

Author

Nouchi, Yuki, additional, Munetsuna, Eiji, additional, Yamada, Hiroya, additional, Yamazaki, Mirai, additional, Ando, Yoshitaka, additional, Mizuno, Genki, additional, Fujii, Ryosuke, additional, Kageyama, Itsuki, additional, Wakasugi, Takuya, additional, Sakakibara, Tomohide, additional, Teshigawara, Atsushi, additional, Ishikawa, Hiroaki, additional, Shimono, Yohei, additional, Suzuki, Koji, additional, Hashimoto, Shuji, additional, and Ohashi, Koji, additional

Published
2022
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11. Differential effects of excess high-fructose corn syrup on the DNA methylation of hippocampal neurotrophic factor in childhood and adolescence

Author

Kageyama, Itsuki, primary, Yamada, Hiroya, additional, Munetsuna, Eiji, additional, Yamazaki, Mirai, additional, Ando, Yoshitaka, additional, Mizuno, Genki, additional, Fujii, Ryosuke, additional, Nouchi, Yuki, additional, Wakasugi, Takuya, additional, Sakakibara, Tomohide, additional, Teshigawara, Atsushi, additional, Ishikawa, Hiroaki, additional, Shimono, Yohei, additional, Suzuki, Koji, additional, Hashimoto, Shuji, additional, and Ohashi, Koji, additional

Published
2022
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12. Maternal High-Fructose Corn Syrup Intake Impairs Corticosterone Clearance by Reducing Renal 11β-Hsd2 Activity via miR-27a-Mediated Mechanism in Rat Offspring.

Author

Nouchi, Yuki, Munetsuna, Eiji, Yamada, Hiroya, Yamazaki, Mirai, Ando, Yoshitaka, Mizuno, Genki, Ikeya, Miyuki, Kageyama, Itsuki, Wakasugi, Takuya, Teshigawara, Atsushi, Hattori, Yuji, Tsuboi, Yoshiki, Ishikawa, Hiroaki, Suzuki, Koji, and Ohashi, Koji

Abstract

We previously reported that maternal fructose consumption increases blood corticosterone levels in rat offspring. However, the underlying mechanism of action remains unclear. In the present study, we aimed to elucidate the molecular mechanism by which maternal high-fructose corn syrup (HFCS) intake increases circulating GC levels in rat offspring (GC; corticosterone in rodents and cortisol in humans). Female Sprague Dawley rats received HFCS solution during gestation and lactation. The male offspring were fed distilled water from weaning to 60 days of age. We investigated the activities of GC-metabolizing enzymes (11β-Hsd1 and 11β-Hsd2) in various tissues (i.e., liver, kidney, adrenal glands, muscle, and white adipose tissue) and epigenetic modification. 11β-Hsd2 activity decreased in the kidney of the HFCS-fed dams. Moreover, the epigenetic analysis suggested that miR-27a reduced Hsd11b2 mRNA expression in the kidney of offspring. Maternal HFCS-induced elevation of circulating GC levels in offspring may be explained by a decrease in 11β-Hsd2 activity via renal miR-27a expression. The present study may allow us to determine one of the mechanisms of GC elevation in rat offspring that is often observed in the developmental origins of the health and disease (DOHaD) phenomenon. [ABSTRACT FROM AUTHOR]

Published
2023
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13. Maternal fructose intake predisposes rat offspring to metabolic disorders via abnormal hepatic programming

Author

Munetsuna, Eiji, primary, Yamada, Hiroya, additional, Yamazaki, Mirai, additional, Ando, Yoshitaka, additional, Mizuno, Genki, additional, Hattori, Yuji, additional, Kageyama, Itsuki, additional, Teshigawara, Atsushi, additional, Nouchi, Yuki, additional, Ishikawa, Hiroaki, additional, Fujii, Ryosuke, additional, Ohta, Yoshiji, additional, Suzuki, Koji, additional, Shimono, Yohei, additional, Ohashi, Koji, additional, and Hashimoto, Shuji, additional

Published
2021
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14. Laboratory analysis of glucose, fructose, and sucrose contents in Japanese common beverages for the exact assessment of beverage-derived sugar intake

Author

Ando, Yoshitaka, primary, Ohta, Yoshiji, additional, Munetsuna, Eiji, additional, Yamada, Hiroya, additional, Nouchi, Yuki, additional, Kageyama, Itsuki, additional, Mizuno, Genki, additional, Yamazaki, Mirai, additional, Fujii, Ryosuke, additional, Ishikawa, Hiroaki, additional, Suzuki, Koji, additional, and Ohashi, Koji, additional

Published
2021
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15. Maternal fructose consumption downregulates hippocampal catalase expression via DNA methylation in rat offspring

Author

Mizuno, Genki, primary, Munetsuna, Eiji, additional, Yamada, Hiroya, additional, Yamazaki, Mirai, additional, Ando, Yoshitaka, additional, Hattori, Yuji, additional, Kageyama, Itsuki, additional, Teshigawara, Atsushi, additional, Nouchi, Yuki, additional, Fujii, Ryosuke, additional, Ishikawa, Hiroaki, additional, Suzuki, Koji, additional, Hashimoto, Shuji, additional, Ohashi, Koji, additional, and Shimono, Yohei, additional

Published
2021
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16. Maternal fructose consumption down-regulates Lxra expression via miR-206-mediated regulation

Author

Yamazaki, Mirai, primary, Munetsuna, Eiji, additional, Yamada, Hiroya, additional, Ando, Yoshitaka, additional, Mizuno, Genki, additional, Fujii, Ryosuke, additional, Nouchi, Yuki, additional, Kageyama, Itsuki, additional, Teshigawara, Atsushi, additional, Ishikawa, Hiroaki, additional, Suzuki, Koji, additional, Shimono, Yohei, additional, Hashimoto, Shuji, additional, and Ohashi, Koji, additional

Published
2020
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17. Laboratory analysis of glucose, fructose, and sucrose contents in Japanese common beverages for the exact assessment of beverage-derived sugar intake.

Author

Ando Y, Ohta Y, Munetsuna E, Yamada H, Nouchi Y, Kageyama I, Mizuno G, Yamazaki M, Fujii R, Ishikawa H, Suzuki K, Hashimoto S, and Ohashi K

Abstract

Objectives: The adverse health effects of consuming sugar-sweetened beverages have been studied worldwide. However, no recent report on the actual sugar contents of Japanese sugar-sweetened beverages is available. Therefore, we analyzed the glucose, fructose, and sucrose contents of common Japanese beverages., Methods: The glucose, fructose, and sucrose contents of 49 beverages (8 energy drinks, 11 sodas, 4 fruit juices, 7 probiotic drinks, 4 sports drinks, 5 coffee drinks, 6 green tea drinks, and 4 black tea drinks) were determined using enzymatic methods., Results: Three zero calorie drinks, 2 sugarless coffee drinks, and 6 green tea drinks contained no sugar. Three coffee drinks contained only sucrose. The orders of median glucose, fructose, and sucrose contents in the categories of beverages containing sugars were as follows: for glucose, fruit juice > energy drink ≥ soda ≫ probiotic drink > black tea drink > sports drink; for fructose, probiotic drink ≥ energy drink > fruit juice > soda ≫ sports drink > black tea drink; and for sucrose, black tea drink > energy drink ≥ probiotic drink > fruit juice > soda > coffee drink ≫ sports drink. The total fructose as a percentage of the total sugar content in the 38 sugar-containing beverages was between 40% and 60%. The total sugar content analyzed was not always equivalent to the carbohydrate content indicated on the nutrition label., Conclusions: These results indicate that information on the actual sugar content of common Japanese beverages is necessary for the exact assessment of beverage-derived sugar intake., Competing Interests: The authors declare that there they have no conflicts of interest.

Published
2023
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