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The Coronavirus pandemic has destabilized many healthcare systems globally since the outbreak was announced. The mode of transmission of the virus has affected the traditional face-to-face mode of seeking healthcare. The world health organization recommends measures, including limiting physical contact as a means of preventing the spread of the virus. Many countries across the world are utilizing telemedicine during this pandemic to provide basic healthcare to their citizens. The implementation of telemedicine in sub- Saharan Africa has encountered many challenges. The surge in the number of covid-19 cases in Ghana calls for drastic measures to contain the repercussions of the pandemic. The Government of Ghana and other private organizations continue to scale up efforts to integrate telemedicine into the mainstream healthcare system. This study seeks to explore and provide insight into the state of telemedicine in Ghana prior to and during the Coronavirus pandemic. This study is a narrative review of literature on the use of telemedicine in Ghana. Data was obtained from PubMed, Embase, ScienceDirect, Scopus and Google Scholar. A secondary search was conducted on government of Ghana health agencies' websites and other relevant websites that published information on telemedicine in Ghana. Literature was analysed and topically discussed based on identified themes. There is an improvement in the number of information and communication technology coordinated healthcare services in Ghana since the outbreak was confirmed. Public-private partnership is required to boost the integration of telemedicine into mainstream healthcare in Ghana., Competing Interests: Conflict of interest: The authors declare no conflict of interest., (©Copyright: the Author(s).)