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534 results on '"Norton, Sally A."'

13. Effects of the Values and Options in Cancer Care Communication Intervention on Personal Caregiver Experiences of Cancer Care and Bereavement Outcomes.

Author

Duberstein, Paul R, Maciejewski, Paul K, Epstein, Ronald M, Fenton, Joshua J, Chapman, Benjamin, Norton, Sally A, Hoerger, Michael, Wittink, Marsha N, Tancredi, Daniel J, Xing, Guibo, Mohile, Supriya, Kravitz, Richard L, and Prigerson, Holly G

Subjects
Humans, Neoplasms, Terminal Care, Health Care Surveys, Communication, Bereavement, Physician-Patient Relations, Medical Oncology, Aged, New York, California, Female, Male, Caregiver Burden, bereavement, cancer, caregiving, communication interventions, patient-physician communication, prolonged grief, purpose in life, satisfaction with care, Behavioral and Social Science, Clinical Trials and Supportive Activities, Depression, Clinical Research, Cancer, Mental Health, 7.1 Individual care needs, Management of diseases and conditions, Mental health, Good Health and Well Being, Clinical Sciences, Nursing, Public Health and Health Services, Gerontology
Abstract

Background: Care teams are increasingly expected to attend to the needs of patient's personal caregivers (e.g., family members). Improving communication among oncologists, patients with advanced cancer, and their personal caregivers might enhance caregivers' experiences of end-of-life (EoL) cancer care and bereavement outcomes. Objective: To explore the effects of the Values and Options in Cancer Care intervention on caregivers' experiences of EoL care and bereavement outcomes. Design: We developed a brief behavioral intervention to improve communication among oncologists, patients with advanced cancer, and their personal caregivers. The intervention was designed to help patients/caregivers ask questions, express concerns, and help oncologists respond effectively. We randomly assigned oncologists (and their patients/caregivers) to the intervention or usual care. Setting/Subjects: Medical oncologists in NY and CA; patients/personal caregivers with advanced cancer. Measurements: Two months after the patient's death, caregivers completed three instruments assessing their experiences of EoL care. Seven months after the patient's death, caregivers completed the Prolonged Grief Disorder-13 (PG-13; primary prespecified outcome), the Purpose-in-Life scale, and scales assessing mental health function, depression, and anxiety. Results: The intervention did not significantly improve caregivers' scores on the PG-13 (p = 0.21), mental health function, depression, or anxiety, but it did improve purpose-in-life scores (p = 0.018). Cohen's d (95% confidence interval) for all three experiences of EoL care outcomes were promising, ranging from 0.22 (-0.19 to 0.63) to 0.39 (-0.07 to 0.86) although none was statistically significant. Conclusion: Preliminary findings show promise that scalable interventions in cancer care settings may improve caregiver experiences with cancer care and some bereavement outcomes.

Published
2019

14. Physician and Patient Characteristics Associated With More Intensive End-of-Life Care.

Author

Duberstein, Paul R, Kravitz, Richard L, Fenton, Joshua J, Xing, Guibo, Tancredi, Daniel J, Hoerger, Michael, Mohile, Supriya G, Norton, Sally A, Prigerson, Holly G, and Epstein, Ronald M

Subjects
Humans, Terminal Care, Hospice Care, Prospective Studies, Attitude of Health Personnel, Health Knowledge, Attitudes, Practice, Paternalism, Aged, Middle Aged, Female, Male, Patient Preference, Advanced cancer, biomedical ethics, chemotherapy, emergency department, end of life, health care utilization, hospitalization, palliative care, patient treatment preferences, physician attitudes, Clinical Research, Behavioral and Social Science, Cancer, Medical and Health Sciences, Anesthesiology
Abstract

ContextAlthough patient and physician characteristics are thought to be predictive of discretionary interventions at the end of life (EoL), few studies have data on both parties.ObjectiveTo test the hypothesis that patient preferences and physician attitudes are both independently associated with discretionary interventions at the EoL.MethodsWe report secondary analyses of data collected prospectively from physicians (n = 38) and patients with advanced cancer (n = 265) in the Values and Options in Cancer Care study. Predictor variables were patient attitudes toward EoL care and physician-reported comfort with medical paternalism, assessed indirectly using a modified version of the Control Preference Scale. We explored whether the magnitude of the physician variable was influenced by the inclusion of particular patient treatment-preference variables (i.e., effect modification). Outcomes were a chemotherapy use score (≤14 days before death [scored 2], 15-31 days before death [scored 1], and >31 days [scored 0]) and an emergency department visit/inpatient admission score (two or more admissions in the last 31 days [scored 2], one admission [1], and 0 admissions [0]) in the last month of life.ResultsChemotherapy scores were nearly 0.25 points higher if patients expressed a preference for experimental treatments with unknown benefit at study entry (0.238 points, 95% CI = 0.047-0.429) or reported an unfavorable attitude toward palliative care (0.247 points, 95% CI = 0.047-0.450). A two-standard deviation difference in physician comfort with medical paternalism corresponded to standardized effects of 0.35 (95% CI = 0.03-0.66) for chemotherapy and 0.33 (95% CI = 0.04-0.61) for emergency department visits/inpatient admissions. There was no evidence of effect modification.ConclusionPatient treatment preferences and physician attitudes are independently associated with higher levels of treatment intensity before death. Greater research, clinical, and policy attention to patient treatment preferences and physician comfort with medical paternalism might lead to improvements in care of patients with advanced disease.

Published
2019

20. Lost Seasonality and Overconsumption of Plants: Risking Oxalate Toxicity

Author

Norton, Sally K.

Subjects
Amaranthaceae, bariatric surgery, bioaccumulation, biological availability, biomineralization, calcium, calcium oxalate, chronic disease, citrates, crystals, deficiency, Dieffenbachia, diet, fatal outcome, food poisoning, food science, foodborne diseases, fruits and vegetables, humans, hyperoxaluria, inflammation, inflammasome, intestinal inflammation, low oxalate diet, legume, microbiota, microbiome, nuts, oxalate, oxalic acid, oxalosis, pain, plant foods, Polygonaceae, raphides, toxicity, kidney failure acute, kidney calculi, renal, renal insufficiency, renal stone, thyroid, toxicology
Published
2017

24. “I have a doctor that handles all the other stuff.” Perceptions of older adults with cancer about discussing aging-related conditions with their oncologists

Author

Kadambi, Sindhuja, Kehoe, Lee, Wells, Megan, Patil, Amita, Lei, Lianlian, Lewis-Thames, Marquita Wenonah, Job, Anna, Zhang, Yingzi, Flannery, Marie, Gilmore, Nikesha, Vogel, Victor G., Philip, Tony, Hopkins, Judith O., Whitehead, Mary, Magnuson, Allison, Mohile, Supriya, and Norton, Sally A.

Published
2025
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36. UK and Ireland Joint Advisory Group (JAG) consensus statements for training and certification in diagnostic endoscopic ultrasound (EUS)

Author

El Menabawey, Tareq, primary, McCrudden, Raymond, additional, Shetty, Dushyant, additional, Hopper, Andrew D, additional, Huggett, Matthew T, additional, Bekkali, Noor, additional, Carroll, Nicholas R, additional, Henry, Elaine, additional, Johnson, Gavin J, additional, Keane, Margaret G, additional, Love, Mark, additional, McKay, Colin J, additional, Norton, Sally, additional, Oppong, Kofi, additional, Penman, Ian, additional, Ramesh, Jayapal, additional, Ryan, Barbara, additional, Siau, Keith, additional, and Nayar, Manu, additional

Published
2023
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42. Variant analysis of grain size related genes in the genus Sorghum

Author

Ananda, Galaihalage K.S., Norton, Sally L., Barnes, Eve, Furtado, Agnelo, Møller, Birger Lindberg, Gleadow, Roslyn, Henry, Robert J., Ananda, Galaihalage K.S., Norton, Sally L., Barnes, Eve, Furtado, Agnelo, Møller, Birger Lindberg, Gleadow, Roslyn, and Henry, Robert J.

Abstract

Grain size and weight are two of the most important determinants of crop yield. Key genes associated with the grain size and weight have been identified in major crops. However, studies on the genetic basis of the grain size and weight related genes in wild Sorghum are limited. In this study, we analysed the variation of grain size related genes using variant analysis of 15 accessions across one cultivated and six tertiary gene pool species representing the five subgenera of Sorghum. A wide variation in grain size related parameters was observed. The highest grain weight, width, and thickness was observed for the accession S. bicolor (L.) Moench 314,746, while the highest grain length was observed for the accession S. macrospermum E.D. Garber 302,367. The wild sorghum species exhibited high morphological diversity. The six candidate genes related to grain size, Sobic.001G335800 (qGW7/GL7), Sobic.001G341700 (GS3), Sobic.002G257900 (GW8), Sobic.003G035400 (GW5/qSW5), Sobic.004G107300 (GW2), and Sobic.009G053600 (GS5) showed polymorphism in the coding sequence regions including variants generating premature stop codons. These variants might contribute to the observed variation in grain size and weight. The tertiary wild sorghum species may be a useful source of genes for understanding and engineering grain size in sorghum and other cereals.

Published
2023

43. UK and Ireland Joint Advisory Group (JAG) consensus statements for training and certification in diagnostic endoscopic ultrasound (EUS).

Author

El Menabawey, Tareq, McCrudden, Raymond, Shetty, Dushyant, Hopper, Andrew D., Huggett, Matthew T., Bekkali, Noor, Carroll, Nicholas R., Henry, Elaine, Johnson, Gavin J., Keane, Margaret G., Love, Mark, McKay, Colin J., Norton, Sally, Oppong, Kofi, Penman, Ian, Ramesh, Jayapal, Ryan, Barbara, Siau, Keith, and Nayar, Manu

Subjects
ENDOSCOPIC ultrasonography, DIAGNOSTIC ultrasonic imaging, SIGMOIDOSCOPY, NEEDLE biopsy, PANCREATIC tumors, CERTIFICATION, ENDOSCOPIC retrograde cholangiopancreatography, PICTURE archiving & communication systems
Published
2024
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44. 128 A single-arm pilot study of an adapted Serious Illness Care Program for older patients with acute myeloid leukemia and myelodysplastic syndromes

Author

LoCastro, Marissa, primary, Mendler, Jason, additional, Norton, Sally, additional, Bernacki, Rachelle, additional, Carroll, Thomas, additional, Klepin, Heidi, additional, Mortaz-Hedjri, Soroush, additional, Jensen-Battaglia, Marielle, additional, Liesveld, Jane, additional, Huselton, Eric, additional, O’Dwyer, Kristen, additional, Baran, Andrea, additional, Flannery, Marie, additional, Kluger, Benzi, additional, and Loh, Kah Poh, additional

Published
2023
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49. Sorghum

Author

Bhattacharya, Anjanabha, Rice, Nicole, Shapter, Frances M., Norton, Sally L., Henry, Robert J., and Kole, Chittaranjan, editor

Published
2011
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