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3. Designing a Portable MPI-2 over Modern Interconnects Using uDAPL Interface

Author

Chai, L., Noronha, R., Gupta, P., Brown, G., Panda, D. K., Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Dough, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Di Martino, Beniamino, editor, Kranzlmüller, Dieter, editor, and Dongarra, Jack, editor

Published
2005
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4. Changes in urinary bladder smooth muscle function in response to colonic inflammation

Author

Noronha, R., Akbarali, H., Malykhina, A, Foreman, R.D., and Greenwood-Van Meerveld, Beverley

Subjects
Rats -- Physiological aspects, Rats -- Diseases, Rattus -- Physiological aspects, Rattus -- Diseases, Bladder -- Properties, Smooth muscle -- Properties, Colon (Anatomy) -- Influence, Biological sciences
Abstract

Visceral organ 'cross talk' is suspected to contribute to multiorgan symptomatology found in conditions such as irritable bowel syndrome and interstitial cystitis. The goal of the present study was to investigate the short- and long-term effects of acute colitis on bladder detrusor muscle contractility. We hypothesized that inflammation of the colon leads to changes in bladder function via direct changes in detrusor smooth muscle contractility. In this study, colonic inflammation was induced in male rats via an enema of trinitrobenzenesulfonic acid (TNBS) (50 mg/kg, 0.5 ml, 25% ethanol). Colitis was confirmed using gross morphology, histology, and measurements of myeloperoxidase activity. Saline enema-treated rats served as controls. Three, 15, and 30 days post-enema treatment, bladder detrusor muscle contractility was investigated in response to electrical field stimulation (EFS), cholinergic agonism with carbachol (CCh), and KCl. During active colonic inflammation (day 3 post-TNBS enema), the bladder detrusor muscle appeared normal and showed no significant inflammation. However, abnormalities in bladder detrusor muscle contractility occurred in response to EFS and CCh but not KCl. During and after recovery from colonic inflammation (days 15 and 30 post-TNBS enema), changes in bladder detrusor muscle contractility in response to EFS and CCh returned to control levels. We found that a transient colonic inflammatory insult significantly attenuates the amplitude of bladder detrusor muscle contractions in vitro, at least in part, through changes in cholinergic innervation, which are reversible after recovery from the colitis. trinitrobenzenesulfonic acid; colon; detrusor muscle; rat

Published
2007

6. One Year of Lamivudine Therapy for Portuguese Patients with Chronic Hepatitis B

Author

Areias, J., Calinas, F., Porto, A., Carvalho, A., Freitas, D., Macedo, G., Noronha, R., Cotter, J., Meliço-Silvestre, A., Peixe, R., Pratas, J., Barrote, D., Teixeira, R., Augusto, F., Carrilho, I., Campante, F., Velosa, J., Carvalho, L., Duarte, M. A., Guerreiro, H., Pires, C., Silva, A., Cotrim, I., Guedes, F., Tomé, L., Marcelino, M., Gonçalves, C., Ferreira, E., Matos, L., Peixe, P., Esteves, J., Valente, T., Simões, C., Marinho, C., Jasmins, L., Vieira, M. J., Marinho, R., Matos, P., Estevens, J., Carrasquinho, J., Salcedo, G., Parada, P., and Teixeira, C.

Published
2003
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18. A Biomarker Panel Associated With Distant Metastasis (DM) in Prostate Cancer Patients Treated With Radiation Therapy Is Also Prognostic for DM in a Large Cohort of Prostatectomy Patients

Author

Pollack, A., primary, Erho, N., additional, Noronha, R., additional, Lam, L., additional, Buerki, C., additional, Abraham, S., additional, Klein, E.A., additional, Karnes, J.R., additional, Den, R.B., additional, Dicker, A.P., additional, Ishkanian, A.S., additional, Davicioni, E., additional, Feng, F.Y., additional, and Stoyanova, R., additional

Published
2015
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19. Risk analysis on fleet size of mining.

Author

Miranda A., MiNiN 2012: 5th International conference on innovation in mine operations Santiago, Chile 20-Jun-1222-Jun-12 Codelco, Noronha R., Miranda A., MiNiN 2012: 5th International conference on innovation in mine operations Santiago, Chile 20-Jun-1222-Jun-12 Codelco, and Noronha R.

Abstract

A study has been carried out on the use of a risk analysis tool to evaluate the economic effects of different fleet sizing scenarios at the Capao Xavier open cast mine, Brazil. Probabilistic simulation was used to determine the loading and hauling parameters that directly influence production capacity of the combined fleets. Simulations focused on rates of physical availability, utilisation and productivity of loading and hauling for ore and wastes, and uncertainties associated with the key variables were quantified. The Monte Carlo method was used and the resulting curves were compared with deterministic calculations using the 'at Risk' software. Data from the dispatching system in 2010, based on daily records of type of equipment and fleet, was used to model the final number of loading machines (excavators or loaders) and trucks necessary to meet the target. A probabilistic model was obtained by fitting real data to the theoretical data. Thus, it was possible to perform a number of simulations according to the theoretical distribution curve selected. Around 10 000 iterations were carried out, which combined the equipment capacities for loading and handling materials to obtain the simulated production capacity., A study has been carried out on the use of a risk analysis tool to evaluate the economic effects of different fleet sizing scenarios at the Capao Xavier open cast mine, Brazil. Probabilistic simulation was used to determine the loading and hauling parameters that directly influence production capacity of the combined fleets. Simulations focused on rates of physical availability, utilisation and productivity of loading and hauling for ore and wastes, and uncertainties associated with the key variables were quantified. The Monte Carlo method was used and the resulting curves were compared with deterministic calculations using the 'at Risk' software. Data from the dispatching system in 2010, based on daily records of type of equipment and fleet, was used to model the final number of loading machines (excavators or loaders) and trucks necessary to meet the target. A probabilistic model was obtained by fitting real data to the theoretical data. Thus, it was possible to perform a number of simulations according to the theoretical distribution curve selected. Around 10 000 iterations were carried out, which combined the equipment capacities for loading and handling materials to obtain the simulated production capacity.

Published
2012

20. Hematúria em estudo

Author

Oliveira, P, Gonçalves, R, Cabral-Ribeiro, J, Vila-Mendes, M, and Noronha, R

Subjects
Hematuria
Abstract

Submitted by Gestor HospitalBraga (bibliotecaria@hospitaldebraga.com.pt) on 2016-10-14T09:53:13Z No. of bitstreams: 1 Hematuria em estudo Fotografia endoscopica 2000 pag 32 e 33 (1).pdf: 309322 bytes, checksum: d9935c917e3f83f5e489ba7aadf5e6c9 (MD5) Made available in DSpace on 2016-10-14T09:53:14Z (GMT). No. of bitstreams: 1 Hematuria em estudo Fotografia endoscopica 2000 pag 32 e 33 (1).pdf: 309322 bytes, checksum: d9935c917e3f83f5e489ba7aadf5e6c9 (MD5) Previous issue date: 2000

Published
2000

21. LAB-EXPERIMENTAL (PRE-CLINICAL) THERAPEUTICS AND PHARMACOLOGY

Author

Yang, F. H., primary, Zhang, B., additional, Zhou, D. J., additional, Bie, L., additional, Tom, M. W., additional, Drummond, D. C., additional, Nicolaides, T., additional, Mueller, S., additional, Banerjee, A., additional, Park, J. W., additional, Prados, M. D., additional, James, D. C., additional, Gupta, N., additional, Hashizume, R., additional, Strohbehn, G. W., additional, Zhou, J., additional, Fu, M., additional, Patel, T. R., additional, Piepmeier, J. M., additional, Saltzman, W. M., additional, Xie, Q., additional, Johnson, J., additional, Bradley, R., additional, Ascierto, M. L., additional, Kang, L., additional, Koeman, J., additional, Marincola, F. M., additional, Briggs, M., additional, Tanner, K., additional, Vande Woude, G. F., additional, Tanaka, S., additional, Klofas, L. K., additional, Wakimoto, H., additional, Borger, D. R., additional, Iafrate, A. J., additional, Batchelor, T. T., additional, Chi, A. S., additional, Madhankumar, A. B., additional, Slagle-Webb, B., additional, Rizk, E., additional, Harbaugh, K., additional, Connor, J. R., additional, Sarkar, G., additional, Curran, G. L., additional, Jenkins, R. B., additional, Kurozumi, K., additional, Ichikawa, T., additional, Onishi, M., additional, Fujii, K., additional, Ishida, J., additional, Shimazu, Y., additional, Date, I., additional, Ebsworth, K., additional, Walters, M. J., additional, Ertl, L. S., additional, Wang, Y., additional, Berahovich, R. D., additional, Zhang, P., additional, Powers, J. P., additional, Liu, S.-C., additional, Al Omran, R., additional, Sullivan, T. J., additional, Jaen, J. C., additional, Brown, M., additional, Schall, T. J., additional, Yusuke, N., additional, Shimizu, S., additional, Shishido-Hara, Y., additional, Shiokawa, Y., additional, Nagane, M., additional, Wang, J., additional, Sai, K., additional, Chen, F.-R., additional, Chen, Z.-P., additional, Shi, Z., additional, Zhang, J., additional, Zhang, K., additional, Han, L., additional, Chen, L., additional, Qian, X., additional, Zhang, A., additional, Wang, G., additional, Jia, Z., additional, Pu, P., additional, Kang, C., additional, Kong, L.-Y., additional, Doucette, T. A., additional, Ferguson, S. D., additional, Hachem, J., additional, Yang, Y., additional, Wei, J., additional, Priebe, W., additional, Fuller, G. N., additional, Qiao, W., additional, Rao, G., additional, Heimberger, A. B., additional, Chen, P.-Y., additional, Ozawa, T., additional, Drummond, D., additional, Santos, R., additional, Torre, J. D., additional, Ng, C., additional, Lepe, E. L., additional, Butowski, N., additional, Prados, M., additional, Bankiewicz, K., additional, James, C. D., additional, Cheng, Z., additional, Gong, Y., additional, Ma, Y., additional, Muller-Knapp, S., additional, Knapp, S., additional, Antonio Chiocca, E., additional, Kaur, B., additional, Yu, J. S., additional, Judkowski, V., additional, Bunying, A., additional, Ji, J., additional, Li, Z., additional, Bender, J., additional, Pinilla, C., additional, Srinivasan, V., additional, Dombovy-Johnson, M., additional, Carson-Walter, E., additional, Walter, K., additional, Xu, Z., additional, Popp, B., additional, Schlesinger, D., additional, Gray, L., additional, Sheehan, J., additional, Keir, S. T., additional, Friedman, H. S., additional, Bigner, D. D., additional, Kut, C., additional, Tyler, B., additional, McVeigh, E., additional, Li, X., additional, Herzka, D., additional, Grossman, S., additional, Lasky, J. L., additional, Panosyan, E., additional, Meisen, W. H., additional, Hardcastle, J., additional, Wojton, J., additional, Wohleb, E., additional, Alvarez-Breckenridge, C., additional, Nowicki, M., additional, Godbout, J., additional, Lee, S. Y., additional, Sheehan, J. M., additional, Yin, S., additional, Kaluz, S., additional, Devi, S. N., additional, de Noronha, R., additional, Nicolaou, K. C., additional, Van Meir, E. G., additional, Lachowicz, J. E., additional, Demeule, M., additional, Che, C., additional, Tripathy, S., additional, Jarvis, S., additional, Currie, J.-C., additional, Regina, A., additional, Nguyen, T., additional, Castaigne, J.-P., additional, Zielinska-Chomej, K., additional, Mohanty, C., additional, Viktorsson, K., additional, Lewensohn, R., additional, Driscoll, J. J., additional, Alsidawi, S., additional, Warnick, R. E., additional, Rixe, O., additional, deCarvalho, A. C., additional, Irtenkauf, S., additional, Hasselbach, L., additional, Xin, H., additional, Mikkelsen, T., additional, Sherman, J. H., additional, Siu, A., additional, Volotskova, O., additional, Keidar, M., additional, Gibo, D. M., additional, Dickinson, P., additional, Robertson, J., additional, Rossmeisl, J., additional, Debinski, W., additional, Nair, S., additional, Schmittling, R., additional, Boczkowski, D., additional, Archer, G., additional, Sampson, J. H., additional, Mitchell, D. A., additional, Miller, I. S., additional, Didier, S., additional, Murray, D. W., additional, Issaivanan, M., additional, Coniglio, S. J., additional, Segall, J. E., additional, Al-Abed, Y., additional, Symons, M., additional, Fotovati, A., additional, Hu, K., additional, Triscott, J., additional, Bacha, J., additional, Brown, D. M., additional, Dunn, S. E., additional, Daniels, D. J., additional, Peterson, T. E., additional, Dietz, A. B., additional, Knutson, G. J., additional, Parney, I. F., additional, Diaz, R. J., additional, Golbourn, B., additional, Picard, D., additional, Smith, C., additional, Huang, A., additional, Rutka, J., additional, Saito, N., additional, Fu, J., additional, Yao, J., additional, Wang, S., additional, Koul, D., additional, Yung, W. K. A., additional, Yuan, Y., additional, Sulman, E. P., additional, Colman, H., additional, Lang, F. F., additional, Slat, E. A., additional, Herzog, E. D., additional, Rubin, J. B., additional, Carminucci, A. S., additional, Amendolara, B., additional, Leung, R., additional, Lei, L., additional, Canoll, P., additional, Bruce, J. N., additional, Wojton, J. A., additional, Chu, Z., additional, Kwon, C.-H., additional, Chow, L. M., additional, Palascak, M., additional, Franco, R., additional, Bourdeau, T., additional, Thornton, S., additional, Qi, X., additional, Kitange, G. J., additional, Mladek, A. C., additional, Su, D., additional, Carlson, B. L., additional, Schroeder, M. A., additional, Pokorny, J. L., additional, Bakken, K. K., additional, Gupta, S. K., additional, Decker, P. A., additional, Wu, W., additional, Sarkaria, J. N., additional, Oddou, M. P., additional, Mollard, A., additional, Call, L. T., additional, Vakayalapati, H., additional, Warner, S. L., additional, Sharma, S., additional, Bearss, D. J., additional, Chen, T. C., additional, Cho, H., additional, Wang, W., additional, Hofman, F. M., additional, Flores, C. T., additional, Snyder, D., additional, Sanchez-Perez, L., additional, Pham, C., additional, Friedman, H., additional, Woolf, E., additional, Abdelwahab, M. G., additional, Turner, G., additional, Preul, M. C., additional, Lynch, A., additional, Rho, J. M., additional, Scheck, A. C., additional, Salphati, L., additional, Heffron, T. P., additional, Alicke, B., additional, Barck, K., additional, Carano, R. A., additional, Cheong, J., additional, Greve, J., additional, Lee, L. B., additional, Nishimura, M., additional, Pang, J., additional, Plise, E. G., additional, Reslan, H. B., additional, Zhang, X., additional, GOuld, S. G., additional, Olivero, A. G., additional, Phillips, H. S., additional, Zadeh, G., additional, Jalali, S., additional, Voce, D., additional, Wei, Z., additional, Shijun, K., additional, Nikolai, K., additional, Josh, W., additional, Clayton, C., additional, Bakhtiar, Y., additional, Alkins, R., additional, Burgess, A., additional, Ganguly, M., additional, Wels, W., additional, Hynynen, K., additional, Li, Y. M., additional, Jun, H., additional, Daniel, V., additional, Walter, H. A., additional, Nakashima, H., additional, Nguyen, T. T., additional, Shalkh, I., additional, Goins, W. F., additional, Chiocca, E. A., additional, Pyko, I. V., additional, Nakada, M., additional, Furuyama, N., additional, Lei, T., additional, Hayashi, Y., additional, Kawakami, K., additional, Minamoto, T., additional, Fedulau, A. S., additional, and Hamada, J.-i., additional

Published
2012
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25. Synthesis of Halipeptins A and D

Author

Nicolaou, K., primary, Lizos, D., additional, Kim, D., additional, Schlawe, D., additional, de Noronha, R., additional, Longbottom, D., additional, Rodriquez, M., additional, Bucci, M., additional, and Cirino, G., additional

Published
2006
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32. Designing a Portable MPI-2 over Modern Interconnects Using uDAPL Interface.

Author

Martino, Beniamino Di, Kranzlmüller, Dieter, Dongarra, Jack, Chai, L., Noronha, R., Gupta, P., Brown, G., and Panda, D. K.

Abstract

In the high performance computing arena, there exist several implementations of MPI-1 and MPI-2 for different networks. Some implementations allow the developer to work with multiple networks. However, most of them require the implementation of a new device, before they can be deployed on a new networking interconnect. The emerging uDAPL interface provides a network-independent interface to the native transport of different networks. Designing a portable MPI library with uDAPL might allow the user to move quickly from one networking technology to another. In this paper, we have designed the popular MVAPICH2 library to use uDAPL for communication operations. To the best of our knowledge, this is the first open-source MPI-2 compliant implementation over uDAPL. Evaluation with micro-benchmarks and applications on InfiniBand shows that the implementation with uDAPL performs comparably with that of MVAPICH2. Evaluation with micro-benchmarks on Myrinet and Gigabit Ethernet shows that the implementation with uDAPL delivers performance close to that of the underlying uDAPL library. Keywords: MPI-1, MPI-2, uDAPL, InfiniBand, Myrinet, Gigabit Ethernet, Cluster. [ABSTRACT FROM AUTHOR]

Published
2005
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37. Incidental focal colonic lesions found on 18Fluorodeoxyglucose positron emission tomography/computed tomography scan: further support for a national guideline on definitive management.

Author

Farquharson, A. L., Chopra, A., Ford, A., Matthews, S., Amin, S. N., and De Noronha, R.

Subjects
COLON cancer patients, PRECANCEROUS conditions, POSITRON emission tomography, POLYPS, COLONOSCOPY, MEDICAL protocols
Abstract

Aim 18Fluorodeoxyglucose (18FDG) positron emission tomography/computed tomography (PET/CT) is an established part of staging in a wide variety of malignancies. Incidental abnormal uptake of 18FDG of unknown significance is frequently encountered. Therefore, we investigated patients with abnormal colonic uptake of 18FDG, determined by PET/CT images, using colonoscopy. Method The radiology reports of all patients referred to a tertiary referral centre for a PET/CT scan were reviewed retrospectively. Patients with abnormal colonic uptake of 18FDG were identified and the PET/CT findings were correlated with colonoscopic findings. Results Of 555 consecutive patients identified over a 26-month period, 53 had abnormal colonic uptake of 18FDG, as determined by PET/CT images. Twenty-nine were not investigated following discussion in a specialist multidisciplinary (MDT) meeting, according to local protocol. Twenty out of 24 patients investigated by endoscopy had a colonic lesion correlating to the site identified on the PET/CT image: 16 patients had tubulovillous adenomas (nine of which were > 10 mm), two had invasive adenocarcinomas, two had diverticular disease and one had collagenous colitis; no colonic lesion was detected in three. These findings were incidental and not related to the primary diagnosis for which the scan was being performed. Accordingly, a positive predictive value of 83% is associated with the finding of abnormal uptake of 18FDG on PET/CT images. Conclusion Incidental abnormal colonic uptake of 18FDG, determined by a PET/CT scan requires definitive colonic investigation in patients suitable for further treatment because significant colonic pathology is frequently identified. The benefit of this approach should be discussed in specialist MDT meetings and tailored to each patient; however, national guidelines for management are required. [ABSTRACT FROM AUTHOR]

Published
2012
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38. Neo-XY body: an analysis of XY1Y2 meiotic behavior in Carollia (Chiroptera, Phyllostomidae) by chromosome painting.

Author

Noronha, R. C. R., &Nagamachi, C. Y, O’Brien, P. C. M., Ferguson-Smith, M. A., and Pieczarka, J. C.

Subjects
*CYTOGENETICS, *CAROLLIA, *PHYLLOSTOMIDAE, *BATS, *GENETIC sex determination, *FLUORESCENCE in situ hybridization
Abstract

Classical and molecular cytogenetic analyses of mitotic and meiotic cells were performed on two species of Carollia from the family Phyllostomidae (Chiroptera), which have an XX/XY1Y2 sex determination system. Our results show that the species Carollia perspicillata and Carollia brevicauda have the same Xq-autosome translocation (neo-X). Using multicolor FISH we observed different levels of condensation of the original X and Y chromosomes when compared to the translocated autosomal segment, a likely consequence of the nucleolar organizer region blocking spreading of inactivation to the autosomal region of the neo-X. The use of chromosome painting showed the behavior of the sex chromosome trivalent – here called the ‘neo-XY body’ – in meiosis. We compared the variation between the condensation of the original X and Y and the autosome-sex chromosome axis and described the pairing between the original X-Y segments (pseudoautosomal region) and the XY2 homologous segments, suggesting genetic activity of the latter during meiosis. Copyright © 2009 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]

Published
2009
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42. Motivação no ensino e na assistência de enfermagem

Author

Noronha R

Subjects
Nursing care, Medical education, Team nursing, Nursing, Nursing research, Nursing theory, MEDLINE, Nurse education, Psychology, General Nursing
Abstract

Com base em um referencial bibliográfico, a autora discute e analisa o processo motivacional na assistência e no ensino de enfermagem. Pretende com este trabalho trazer subsídios para enriquecimento sobre o assunto, procurando mostrar sua importância para a atuação do enfermeiro, quer seja junto ao indivíduo, sua família e a comunidade onde vive, quer seja quando docente, junto ao estudante de enfermagem. Para atingir tais metas, a autora se baseou em vários autores, principalmente em trabalhos realizados na área de enfermagem, em teorias sobre a motivação e na própria experiência.

Published
1984

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