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Urban planning, which is inherently multifaceted, requires the development of innovative tools to navigate its complexities. This study introduces a pioneering approach that presents an AI-driven framework tailored for urban data collection and analysis. The impetus for this framework is highlighted through the unique narrative of Most city, which is profoundly transformed by mininginduced displacement and resettlement. While most cities serve as a vivid illustration of the challenges cities can face, especially in the wake of industrial imperatives, this study focuses on the potential of AI in addressing such challenges. The proposed framework, while grounded in advanced computational methodologies, is designed with keen emphasis on real-world applications, ensuring its relevance and adaptability. By integrating Most city’s detailed account with this AI-centric methodology, this study emphasizes the importance of a data-driven approach in understanding and addressing urban dilemmas. Importantly, this study is preparatory, laying the groundwork for the framework’s future application, especially in contexts such as Most city. By bridging advanced AI techniques with tangible urban challenges, this research illuminates a path forward, suggesting a future in which urban planning is not only informed by data but also empowered by AI’s analytical process.

The ageing European population is driving the demand for age-friendly communities that support older individuals’ health and well-being. As communities navigate this transition, Transition Design emerges as a promising approach for addressing complex social and environmental challenges. This study explores the potential of Transition Design to create age-friendly communities in Europe. Drawing on examples from several European countries, this paper describes the key principles of Transition Design and how they can be applied to the development of age-friendly communities. This article highlights the importance of participatory processes in involving older people and other stakeholders in the design process, and discusses the role of technology in creating more accessible and inclusive environments. It also considers some of the challenges of implementing a transition design approach in a European context. In conclusion, this study asserts that Transition Design offers a promising approach for creating sustainable, inclusive, and responsive age-friendly communities.

Smart cities continue to be discussed throughout Europe as a result of the continent’s rising urbanization and the need for sustainable development. Artificial intelligence (AI) has the potential to significantly promote this shift by assisting cities in becoming more effective, sustainable, and receptive to the requirements of their residents. The goal of this study is to examine the potential and difficulties of AI in urban development and present a framework for incorporating AI into city planning and management in European cities. This is done by analyzing case study examples from European cities and examining primary and secondary data sources, with the aim of providing a comprehensive framework for the sustainable integration of AI systems. This study presents a set of ethical and inclusive AI criteria, such as transparency, inclusion, and accountability, to enable responsible AI research and implementation. It continues by emphasizing the need for efficient AI integration in smart cities and pushing for a holistic AI-enabled transition to inclusive and sustainable smart cities.

Metastases to the breast from a nonmammary primary are rare. Primary fallopian tube carcinoma is one of the rarest malignancies of the female genital tract. Therefore, breast metastases from primary fallopian tube carcinoma are considered extremely rare. In this article, we shared the case of serous carcinoma of fallopian tube with metastasis to an intramammary lymph node, presenting as a solitary breast mass. On initial staging 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography for this patient with serous carcinoma of fallopian tube, a solitary FDG avid breast mass was found, along with FDG avid multistation nodes. The breast mass was evaluated with diagnostic mammogram and ultrasound and eventually biopsy of this mass revealed metastatic lymph node from carcinoma of fallopian tube origin.

Thyroid cancer is a type of malignancy that is considered to have a low morbidity and an indolent disease course in most patients. Though some of its pathologic variants such as anaplastic carcinoma may present with advanced disease staging, it is important to consider the possibility of metastasis to thyroid which may present like a thyroid primary. Solid organ carcinomas form the bulk of the uncommon metastasis to the thyroid, though sarcomas from various organs also rarely exhibit this activity. Literature demonstrating sound diagnostic criteria for these occurrences is sparse. We present a case of uterine sarcoma with distant metastasis to the thyroid gland that initially presented as hypercapnic respiratory failure. Only an inpatient episode of uterine bleeding prompted our team to explore the potential of a metastatic process. Our diagnosis was made utilizing a multidisciplinary approach that we feel is important for clinicians dealing with metastatic disease to the thyroid. In addition to sound physical exam, and use of appropriate imaging modality, we feel it is essential to utilize a detailed cytohistologic specimen evaluation, immunohistochemistry, and genetic sequencing to effectively work up such patients. Although our patient did not survive her hospital stay, we hope this paper brings greater awareness of this malignancy and acts as a benchmark for diagnosing such an unusual remote primary.

Colorectal carcinoma with noncohesive tumor cells has been described in tumors with signet ring cells (mucinous adenocarcinoma and signet ring cell adenocarcinoma) and rhabdoid feature (carcinoma with sarcomatoid component). Cases of carcinoma with plasmacytoid morphology are rare in the gastrointestinal tract, and a single case of plasmacytoid colorectal carcinoma has been reported. We report the case of a 37-year-old woman who presented with urinary symptoms, hematuria, and abdominal pain. Imaging studies showed segmental sigmoid wall thickening with pericolic infiltration and focal bladder wall thickening. The cystoscopy with transurethral resection of bladder tumor revealed muscle invasion, dis-cohesive carcinoma with plasmacytoid morphology, which was initially misdiagnosed as the plasmacytoid urothelial carcinoma. Immunohistochemical stains showed the tumor cells to be positive for CDX2, CK20, and SATB2 and negative for p63, GATA3, CK7, and Uroplakin II, indicating the colorectal origin of the tumor. The subsequent colonic wall biopsy showed the same tumor. Molecular studies identified BRAF V600E, SMAD4, and p53 mutations associated with aggressive colorectal adenocarcinoma with mucinous/signet ring cell features. Further whole-exome sequencing and whole transcriptome analysis confirmed the colorectal origin of the tumor. This rare colorectal adenocarcinoma with the plasmacytoid feature may represent the signet ring cell adenocarcinoma lacking extracellular mucin or intracellular vacuole. Diagnosis of this rare histological subtype of colorectal carcinoma is important, particularly in the unusual presentation of this aggressive tumor.

The paper deals with the use of waste as a resource for urban regeneration and social integration of marginalised communities in Amman (Jordan) through the case study of the Jabal al Jofeh refugee camp, a poor ‘informal’ area with a Palestinian refugee population characterised by high crime, unemployment and poverty rates. The proposed Urban Regeneration Plan focuses on the use and reuse of accumulated waste as construction material and on the creation of a neighbourhood network for the collection, sorting and recycling of waste and its transformation into saleable products that generate income for the community. The vulnerable area of the camp is thus transformed into an active connection with the culturally rich historic centre of Amman through a human-centred approach to urban design and planning, creating a sustainable micro-economy with people as its main resource.

Prostate intraepithelial neoplasia is described as a precursor lesion to prostatic adenocarcinoma. High-grade prostate intraepithelial neoplasia (HGPIN) is classified as both grade 2 and 3 prostate intraepithelial neoplasia due to inconsistency between pathologists’ findings. In our study, we assessed the interobserver variability in the diagnosis of HGPIN among genitourinary and nongenitourinary pathologists. All cases with prostate adenocarcinoma diagnosis on needle core biopsy, radical prostatectomy, and transurethral resection of prostate (TURP) between the years 2005 and 2014 were included. In total, 191 prostate cancer cases were included: 109 needle core biopsies, 45 radical prostatectomies, and 37 TURP. All were independently reviewed by 2 urologic pathologists for the presence of HGPIN. High-grade prostate intraepithelial neoplasia was diagnosed in 65 cases (34%), among which the lesion was recognized by the reporting pathologists in 36 (55%) of the cases and was missed in 29 (45%) of the cases with a κ coefficient of 0.53. There was a moderate interobserver agreement in the diagnosis of HGPIN. Consultation with genitourinary pathologist can improve HGPIN diagnosis.