511 results on '"Non-operative"'
Search Results
2. Long term outcomes from uncorrected hypospadias: a scoping review
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Bohane, E., Murphy, M., Chierigo, F., Mantica, G., Adamowicz, J., Campos-Juanatey, F., Cocci, A., Frankiewicz, M., Rosenbaum, C.M., Verla, W., Waterloos, M., Białek, Ł., Madec, F.X., Oszczudłowski, M., Vetterlein, M.W., and Redmond, E.J.
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- 2025
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3. Resultados a largo plazo de hipospadias no intervenidos: una revisión exploratoria
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Bohane, E., Murphy, M., Chierigo, F., Mantica, G., Adamowicz, J., Campos-Juanatey, F., Cocci, A., Frankiewicz, M., Rosenbaum, C.M., Verla, W., Waterloos, M., Białek, Ł., Madec, F.X., Oszczudłowski, M., Vetterlein, M.W., and Redmond, E.J.
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- 2025
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4. Effectiveness of clinical examination and radiological investigations in the success of selective non-operative management of abdominal gunshot injuries.
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Mansor, Salah, Ziu, Naman, Bujazia, Ayoub, Eltarhoni, Ahmed, and Alsharif, Jamal
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GUNSHOT wounds , *ABDOMINAL injuries , *PLEURAL effusions , *HOSPITAL admission & discharge , *HOSPITAL emergency services - Abstract
Objective: Non-operative management of abdominal gunshot injuries has become the standard care in the selected cases of modern surgery with an acceptable success rate to reduce the incidence of unnecessary laparotomies. In this study, an assessment was conducted to determine how the success of this form of management was impacted by physical examination and radiological investigation. Material and Methods: This is a retrospective study that includes all consecutive penetrating abdominal gunshot wound patients who were admitted to the emergency department between February 2011 and December 2018. All patients with superficial gunshot wounds were excluded. The decision to perform a laparotomy on injured patients was the study’s primary endpoint while the discharge of patients without surgery was its secondary endpoint. Results: Of 429 torso gunshot wound patients, 411 were males. Average age was 29.5 years. Forty-one (9.5%) were initially treated by selective nonoperative management. Five selective non-operative management patients underwent delayed laparotomy within 12 hours after admission without complication. In the end, 36 (88%) of the 41 patients were successfully treated without undergoing surgery, with only one patient developing pleural effusion and no mortality attributed to it. Of all injured patients, 45 (10.5%) patients had a negative laparotomy, with two of them subsequently developing an incisional hernia. Conclusion: The success rate of non-operative management of torso gunshot injuries can be increased significantly in stable patients by adopting the strategy of repeated physical examinations alone or in conjunction with simultaneous radiological imaging. [ABSTRACT FROM AUTHOR]
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- 2024
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5. Outcomes of non-surgical management of non-condylar mandibular fractures: a systematic review and meta-analysis.
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Rashid, Junaid, Wu, Sophie, Naredla, Pradyumna, and Breeze, John
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TREATMENT of fractures ,ECONOMIC impact ,MANDIBLE ,TREATMENT effectiveness ,ADULTS ,MANDIBULAR fractures - Abstract
Surgical intervention utilising open and (less commonly) closed reduction, are the main methods for the management of fractures of the mandible that do not involve the condyle or coronoid. Non-surgical management of these fracture patterns is rare. This systematic review aimed to collate current evidence surrounding this topic. A systematic review was undertaken using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Inclusion criteria were adults with mandibular fractures. Exclusion criteria included any form of surgical intervention including open or closed reduction, and fractures of the condyle or coronoid. Four studies satisfied the eligibility criteria and comprised 80 patients. A total of 69 patients (86%) who were managed non-surgically produced satisfactory clinical outcomes with no surgical intervention required. The evidence suggests that non-surgical management can successfully avoid surgery in most cases when certain criteria are applied. This has huge health economic implications as it reduces morbidity and requirements for theatre and inpatient stay. Further research is required to establish which fracture patterns are most amenable to this approach, the most effective non-surgical instructions, and the recommended follow-up period. [ABSTRACT FROM AUTHOR]
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- 2024
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6. Obesity classification predicts early complications and mortality after acetabular fracture.
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Wier, Julian, Firoozabadi, Reza, and Patterson, Joseph T.
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OBESITY complications , *OBESITY risk factors , *RISK assessment , *ACETABULUM (Anatomy) , *HIP fractures , *BODY mass index , *DATA analysis , *RESEARCH funding , *MULTIPLE regression analysis , *HOSPITAL patients , *SURGICAL complications , *STATISTICS , *CONFIDENCE intervals , *OBESITY - Abstract
Introduction: Obesity remains a global epidemic. The effect of obesity on the risk of complications after acetabular fracture is unknown. Here, we evaluate the effect of BMI on early complications and mortality after acetabular fracture. We hypothesize that the risk of inpatient complications and mortality will be greater in patients with high BMI when compared to those with normal BMI. Methods: Adult patients with acetabular fracture were identified via the Trauma Quality Improvement Program data from 2015 to 2019. The primary outcome was overall complication rate with reference to normal-weight patients (BMI = 25–30 kg/m2). The secondary outcome was rates of death. The association of obesity class on the primary and secondary outcomes was assessed using Bonferroni-corrected multiple logistic regression models considering patient, injury, and treatment covariates. Results: A total of 99,721 patients with acetabular fracture were identified. Class I obesity (BMI = 30–35 kg/m2) was associated with 1.2 greater adjusted relative risk (aRR; 95% confidence interval (CI) 1.1–1.3) of any adverse event, without significant increases in adjusted risk of death. Class II obesity (BMI = 35–40 kg/m2) was associated with aRR = 1.2 (95% CI 1.1–1.3) of any adverse event and aRR = 1.5 (95% CI 1.2–2.0) of death. Class III obesity (BMI ≥ 40 kg/m2) was associated with aRR = 1.3 (95% CI 1.2–1.4) of any adverse event and aRR = 2.3 (95% CI 1.8–2.9) of death. Conclusion: Obesity is associated greater risk of adverse events and death following acetabular fracture. Obesity severity classification scales with these risks. [ABSTRACT FROM AUTHOR]
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- 2024
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7. Non-operative management of metacarpal II-IV fractures: A retrospective study from a tertiary hand unit.
- Author
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Turna, Adam, Stringer, Immy, Jemec, Barbara, Anadkat, Meera, Arize, Chinedum, and Nikkhah, Dariush
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Metacarpal fractures produce significant hand disability, and non-operative management of these fractures can produce satisfactory functional outcomes with few complications. However, most studies assessing non-operative outcomes of metacarpal fractures revolves around metacarpals I and V, which possess different anatomy. Therefore, further investigation into outcomes after non-operative treatment of metacarpals II-IV is required to inform management decisions and allow modification of the rehabilitation protocols to specific fracture patterns. All records for 76 non-operative patients presenting with fractures of metacarpals II-IV to our tertiary centre in the year 2019 were retrospectively reviewed. Patients were treated with thermoplastic splinting or fibreglass casting with a rehabilitative exercise programme. Range of motion (ROM) of the Metacarpophalangeal (MCPJ), Proximal Interphalangeal (PIPJ), and Distal Interphalangeal joints (DIPJ), return to work time, and complications were assessed at 12 weeks post-treatment. Mean return to work time was 5.4 weeks, and patients did not report any serious adverse events; the main complication reported was tenderness on palpation (20%). The MCPJ exhibited the poorest ROM (9° flexion reduction relative to the healthy hand). Metacarpal II fractures were associated with significantly worse MCPJ flexion than metacarpal III (p = 0.022) and metacarpal IV (p = 0.049) fractures. Fractures of the metacarpal base were associated with superior MCPJ flexion (p = 0.004) but longer return to work time (p = 0.042) than head fractures. Spiral fractures were associated with shorter return to work time (p = 0.043) and superior ROM results (p = 0.041). In conclusion, outcomes of the non-operative treatment of metacarpal II-IV fractures are highly dependent on the location and pattern of the fracture, and this should be considered during clinical decision making. [ABSTRACT FROM AUTHOR]
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- 2024
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8. Non‐operative management of uncomplicated appendicitis in children: a randomized, controlled, non‐inferiority study evaluating safety and efficacy.
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Adams, Susan Elizabeth, Perera, Meegodage Roshell Swindri, Fung, Saskia, Maxton, Jordon, and Karpelowsky, Jonathan
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APPENDICITIS , *SURGICAL emergencies , *RANDOMIZED controlled trials , *PATIENT selection , *PEDIATRIC emergencies , *APPENDECTOMY - Abstract
Background: Appendicitis is the commonest paediatric surgical emergency. Adult studies suggest non‐operative management (NOM) may have a place in care. There have been no adequately powered randomized controlled trials in children. Objective: to determine the safety and efficacy of NOM for paediatric simple appendicitis. Methods: A non‐inferiority randomized controlled trial was conducted comparing operative (OM) to NOM of SA in children aged five‐15 years. Primary outcome was treatment success (no unplanned or unnecessary operation, or complication) at 30 days and 12 months, with a non‐inferiority margin of 15%. (anzctr.org.au: ACTRN12616000788471). Results: From 11 June 2016 to 30 November 2020, 222 children were randomized: 94 (42.34%) to OM and 128 (57.66%) to NOM. Non‐inferiority of NOM was not demonstrated at either time point, with 45.67% of NOM patients subsequently undergoing operation. There was no significant difference in complications. Conclusions: While noninferiority was not shown, NOM was safe, with no difference in adverse outcomes between the two groups. Further research to refine the place of NOM of simple appendicitis in children is required, including nuanced patient selection, longer term evaluation, the place of choice, and the acceptability of the treatment for children and their carers. [ABSTRACT FROM AUTHOR]
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- 2024
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9. Construction of a new tool for predicting cancer-specific survival in papillary thyroid cancer patients who have not received surgery.
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Sanjun Chen, Yanmei Tan, Xinping Huang, and Yanfei Tan
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RECEIVER operating characteristic curves ,PROPENSITY score matching ,THYROID cancer ,DECISION making ,REGRESSION analysis - Abstract
Background: The prevalence of papillary thyroid cancer is gradually increasing and the trend of youthfulness is obvious. Some patients may not be able to undergo surgery, which is the mainstay of treatment, due to physical or financial reasons. Therefore, the prediction of cancer-specific survival (CSS) in patients with non-operated papillary thyroid cancer is necessary. Methods: Patients’ demographic and clinical information was extracted from the Surveillance, Epidemiology, and End Results database. SPSS software was used to perform Cox regression analyses as well as propensity score matching analyses. R software was used to construct and validate the nomogram. X-tile software was used to select the best cutoff point for patient risk stratification. Results: A total of 1319 patients were included in this retrospective study. After Cox regression analysis, age, grade, T stage, M stage, radiotherapy, and chemotherapy were used to construct the nomogram. C-index, calibration curves, and receiver operating characteristic curves all verified the high predictive accuracy of the nomogram. The decision curve analysis demonstrated that patients could gain clinical benefit from this predictive model. Survival curve analysis after propensity score matching demonstrated the positive effects of radiotherapy on CSS in non-operated patients. Conclusion: Our retrospective study successfully established a nomogram that accurately predicts CSS in patients with non-operated papillary thyroid cancer and demonstrated that radiotherapy for operated patients can still help improve prognosis. These findings can help clinicians make better choices. [ABSTRACT FROM AUTHOR]
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- 2024
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10. Patient Satisfaction Following Non-Operative Treatment of Geriatric Hip Fractures: A Case-Control Study.
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Wiseley, Benjamin R., Shin, Edward D., Kuhn, Gabrielle R., Hetzel, Scott J., Johnson, Kristina P., Goodspeed, David C., Doro, Christopher J., and Whiting, Paul S.
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MEDICAL protocols ,HIP fractures ,BODY mass index ,RESEARCH funding ,QUESTIONNAIRES ,TREATMENT effectiveness ,DESCRIPTIVE statistics ,CASE-control method ,PATIENT satisfaction ,COMPARATIVE studies ,DATA analysis software ,DEMENTIA ,COMORBIDITY ,EVALUATION ,OLD age - Abstract
Introduction: A minority of geriatric hip fracture patients pursue non-operative treatment. Compared with surgical patients, non-operative patients have higher mortality rates. However, patient satisfaction following non-operative vs operative treatment has not been investigated extensively. The purpose of this study was to compare satisfaction among non-operatively vs operatively treated hip fracture patients. Methods: We identified patients aged 60+ years with proximal femur fractures treated over a 10-year period. Excluded were patients with isolated greater/lesser trochanteric fractures. Patients or relatives were asked to complete a 6-question survey about their treatment satisfaction. Results: Survey responses from 56 operative and 28 non-operative patients were recorded. Overall, 91.1% of operative and 82.1% of non-operative patients were satisfied with their treatment course (P = 0.260). However, only 71.4% of non-operative patients were satisfied with treatment option explanations vs 83.9% of operative patients (P = 0.014). While only 64.3% of non-operative respondents were satisfied with the ultimate treatment outcome (vs 85.7% of operative patients, P = 0.025), 89.3% of patients in each cohort would choose the same treatment plan again. Discussion: Our findings highlight the complexity of defining patient satisfaction, particularly in a geriatric hip fracture population. Unlike previous studies, we chose a direct approach to quantifying patient satisfaction by asking participants specifically about satisfaction with treatment outcome and the overall treatment course. Additional survey questions were then included to assess factors considered important in treatment satisfaction, such as health care provider treatment explanations, post-treatment mobility, and palliative care service involvement. Conclusions: We identified significant differences between non-operatively and operatively treated geriatric hip fracture patients regarding satisfaction with the explanation of treatment options, and ultimate treatment outcomes. There was no significant difference in overall satisfaction with the treatment course or likelihood of choosing the same treatment again. Further research investigating patient satisfaction following geriatric hip fracture treatment is warranted. [ABSTRACT FROM AUTHOR]
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- 2024
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11. A systematic review of the outcomes of partial ulnar collateral ligament tears of the elbow in athletes treated non-operatively with platelet-rich plasma injection.
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Ifarraguerri, Anna M, Berk, Alexander N, Rao, Allison J, Trofa, David P, Ahmad, Christopher S, Martin, Anthony, Fleischli, James E, and Saltzman, Bryan M
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ULNAR collateral ligament , *PLATELET-rich plasma , *RESEARCH personnel , *TREATMENT effectiveness , *INJECTIONS - Abstract
Background: This study aimed to analyze the effects of platelet-rich plasma (PRP) for partial ulnar collateral ligament (UCL) tears in athletes and predicted positive outcomes. Methods: The researchers systematically reviewed the PubMed, Cochrane CENTRAL, MEDLINE, Scopus, and Google Scholar databases to identify studies with clinical outcomes of PRP for partial UCL tears. They excluded studies that did not stratify data by tear type or included surgical management. Results: Five studies with 156 patients were included. The timing, amount, platelet concentration, type, and number of PRP injections were highly variable among the studies. However, 75% (n = 97/127) of athletes returned to sport (RTS) at a weighted average of 82.1 days (37–84) after PRP injection. One study showed significant improvements in patient-reported outcomes. Two studies showed positive outcomes in the modified Conway scale, complete reconstitution of the UCL in 87% of patients on MRI, and significant improvement in the humeral-ulnar joint space after PRP injection via ultrasound. The Coleman methodology score (CMS) averaged 48/100, indicating an overall poor quality of evidence. Conclusion: This review demonstrates favorable RTS, clinical, and radiographic outcomes in patients receiving PRP for partial UCL tears, but the literature remains heterogeneous and of low quality. Level of Evidence: III [ABSTRACT FROM AUTHOR]
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- 2024
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12. Platelet-rich plasma for nonoperative management of degenerative meniscal tears: A systematic review.
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Elphingstone, Joseph W., Alston, Elijah T., and Colorado, Berdale S.
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MENISCUS injuries ,KNEE pain ,PHYSICAL therapy ,CONSERVATIVE treatment ,MEDICAL information storage & retrieval systems ,MENISCUS (Anatomy) ,DISEASE management ,ARTHROSCOPY ,PLATELET-rich plasma ,CONFIDENCE ,DESCRIPTIVE statistics ,INTRA-articular injections ,SYSTEMATIC reviews ,ORTHOPEDICS ,MEDLINE ,DRUG efficacy ,OSTEOARTHRITIS ,MEDICAL databases ,ONLINE information services ,DISEASE progression - Abstract
Meniscus tears are a common cause of knee pain encountered in orthopedics and sports medicine. There are numerous management strategies, from physical therapy and oral medications to surgery. Recent evidence is more favorable for conservative management, as operative treatment has limited clinical benefits and is associated with an accelerated progression toward osteoarthritis. Injections with orthobiologic therapies, such as platelet-rich plasma (PRP), are emerging as an alternative therapeutic tool for degenerative tears. This study aims to evaluate the latest evidence regarding the efficacy of PRP injections for the nonoperative management of degenerative meniscal pathology. Articles were obtained from Embase, PubMed, World of Science, Cochrane, and Galileo databases after searching "Platelet-rich plasma" AND "Meniscus." Inclusion criteria consisted of original, human studies evaluating the use of platelet-rich plasma for nonoperative management of meniscus tears. A total of 384 articles were screened, with ten studies selected for final inclusion. The pooled study population comprised 686 patients, with an average age ranging from 33 to 53 years, and a 38% female population. Three different injection approaches were utilized, categorized as intra-articular alone (IA), intra-meniscal alone (IM), or a combination of both. Most studies demonstrated improved pain and functionality by 3 months that persisted for at least one year. Within the IA and IM groups, the majority of patients were either radiographically stable (30–70%) or demonstrated interval healing (40–60%). Several studies within IM and combined treatment groups evaluated rates and time to arthroscopy, and found lower failure rates and greater arthroscopy-free survival time than control comparison groups. PRP appears to be a safe and efficacious treatment strategy for degenerative meniscal pathology. However, due to diverse periprocedural techniques, PRP injectate characteristics, and a lack of high-quality studies, additional trials are needed to provide greater a degree of confidence in PRP's clinical impact on patients with meniscus tears. Systematic Review. [ABSTRACT FROM AUTHOR]
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- 2024
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13. Clinical Outcome of Conservatively Managed Midshaft Clavicle Fractures in Adults.
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Shah, Seeyan M., Baba, Asif Nazir, Shah, Azad Ahmad, Wani, Iftikhar H., and Naseem-ul-Gani
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CLAVICLE fractures ,MEDICAL slings ,TREATMENT effectiveness ,BONE surgery ,CLAVICLE ,JOINTS (Anatomy) - Abstract
Clavicle fractures are among the most common skeletal injuries accounting for 2-5% of all adult fractures. Historically, nonoperative treatment of midshaft clavicular fractures was considered the gold standard of care. Furthermore, nonoperative treatment has been challenged by an increasing popularity and rate of surgical fixations in recent years despite a lack of clear evidence in the current literature. The aim of our study was to analyze the short term functional outcome of non-operatively managed displaced mid-shaft clavicle fracture. Method In this prospective observational study, 46 consecutive patient with displaced midshaft clavicle fractures treated non-operatively in the Orthopedics Department at the Hospital for Bone & Joint Surgery, the associated hospital of the Postgraduate Department of Orthopedics, Government Medical College, Srinagar, from May 2021 to May 2023 were followed up to three months. All the patient after the diagnosis of the injury, received clavicle brace and arm pouch sling as non-operative management. Functional outcome assessment was done using the Constant score. Result The mean age of the patient in our study was 36.47 +/-6.42 years. Clavicle fracture predominant involved male gender (84.7% male Vs 15.3% female), right side was involved more commonly than left (71.6% right Vs 28.4% Left) and the most common mode of injury was Road traffic accident (RTA 60.1%, Fall 30.9% and sports 9%). The mean clavicle shortening was 0.865+/- 0.48cm. The mean constant score at final assessment 86.75/100. We observed significant correlation between clavicle fracture shortening and constant score at 3 months (p < 0.001). Conclusion Our study revealed that functional outcome of non-operative management of displaced mid shaft clavicle fracture have a significant correlation with the amount of shortening. [ABSTRACT FROM AUTHOR]
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- 2024
14. Is platelet-rich plasma a new solution for shoulder adhesive capsulitis? A systematic scoping review of the literature.
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El-Swaify, Seif Tarek, Refaat, Mazen A, AbdelWahab, Aly A, Seddik, Mohamed ElSayed E, Mostafa Abdelrazek, Abdelrahman E, Doas, Youssef, and Beshay, Pavly Wagih
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PLATELET-rich plasma , *ADHESIVES , *BIBLIOGRAPHIC databases , *SHOULDER , *ANIMAL models in research , *SHOULDER disorders - Abstract
Background: Platelet-rich plasma (PRP) has shown promising results for adhesive shoulder capsulitis (AC) in pre-clinical models. The aim of this review is to investigate the clinical outcomes of using PRP in AC. Materials and Methods: We conducted a systematic scoping review of the literature using bibliographic databases from inception until the 9th of January 2022 [PubMed, Web of Science, Scopus, and CENTRAL]. Randomized studies were included if they investigated the use of PRP in human patients with a diagnosis of AC. Authors performed individual study quality assessments using the RoB 2 tool. Results: We screened a total of 470 results and 6 were included in the final synthesis. Studies included data of 578 patients with 263 patients receiving PRP (45.5%). All studies used PRP as part of non-operative treatment. PRP was compared to another intervention in all six studies. Four of these studies found PRP to be more effective. No major adverse effects were reported in any study. Conclusion: PRP is a safe treatment option that can be added to the investigative treatment arsenal of AC. Despite showing some favorable results, several limitations and patient-centered questions remain to be addressed by future studies. Level of Evidence: IV. [ABSTRACT FROM AUTHOR]
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- 2024
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15. Systematic Review and Meta-analysis to Compare the Short- and Long-term Outcomes of Non-operative Management With Early Operative Management of Simple Appendicitis in Children After the COVID-19 Pandemic.
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Decker, Emily, Ndzi, Agnes, Kenny, Simon, and Harwood, Rachel
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Non-operative management (NOM) of simple appendicitis is becoming an increasingly researched treatment option. This systematic review aims to describe the short and long-term failure rates of NOM and the complication rate of appendicectomy in children with simple appendicitis. The systematic review was registered a priori (CRD42022322149). Study inclusion criteria are: participants aged ≤ 18 years of age; groups undergoing both NOM and appendicectomy for simple appendicitis; outcomes including one or more of: NOM failure rate at 30 days or 1 year and beyond; study design: RCT or case control study. Four databases were searched and 3 reviewers determined study eligibility and data extraction. Risk of bias was assessed and meta-analysis was performed using Stata. The database search identified 2731 articles, 14 studies met the inclusion criteria; 4 RCTs and 10 case controlled studies. All studies had moderate-serious risk of bias. There were no deaths in either group in any study. Meta-analysis demonstrated a 30 day failure rate of 20 % (95 % CI 11–29 %) and 11 studies reported failure rate at 1 year or beyond at 32 % (95 % CI 25–38 %). Rates of significant complications of appendicectomy was 1 % (95 % CI 0–1 %). Non-operative management of simple appendicitis in children is safe, with moderate early success. The failure rate increases over time, resulting in eventual appendicectomy in a third of the children diagnosed with appendicitis. These data will enable clinicians to have an informed discussion with children and their parents about their treatment options for simple appendicitis. II. [ABSTRACT FROM AUTHOR]
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- 2024
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16. Epidemiology and Management of Distal Radioulnar Injuries at Hadji Boejasin General Hospital, Pelaihari
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Yudha Pratama and Muhammad Iqbal
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druj trauma ,high impact ,low impact ,operative ,non-operative ,Medicine (General) ,R5-920 - Abstract
Distal radius fracture is one of the most common fractures, especially in the elderly. This fracture often followed by an ulna fracture, causing interference with the distal radioulnar joint (DRUJ). The aim of this study is to provide an overview of DRUJ trauma management along with its indications. This research is a retrospective descriptive study. Data collection was carried out from the medical record data of DRUJ trauma patients who were treated through the ED of H. Boejasin General Hospital. There were 19 samples that met the inclusion criteria, aged 18-60 years. A total of 7 patients (36.84%) underwent ORIF, 12 patients (63.16%) LAC (91.67%), and 1 patient underwent SAC (8.33%). Surgery is the main choice of treatment by orthopedic surgeons for DRUJ trauma patients due to high impact injuries, while conservative management is sufficient for low impact injuries.
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- 2024
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17. Calcific bursitis of the Gruberi bursa: a case report
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Patel, Nikhil N., Jose, Jean, and Pravia, Cristina
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- 2024
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18. The Impact of Implementation of Palliative, Non-Operative Management on Mortality of Operatively Treated Geriatric Hip Fracture Patients: A Retrospective Cohort Study.
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Nijdam, Thomas, Schiepers, Tim, Laane, Duco, Schuijt, Henk Jan, van der Velde, Detlef, and Smeeing, Diederik
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HIP fractures , *COHORT analysis , *GERIATRIC surgery , *INTENSIVE care units , *LIFE expectancy , *HOSPITAL mortality - Abstract
(1) Background: Hip fracture patients with very limited life expectancy can opt for non-operative management (NOM) within a palliative care context. The implementation of NOM in the palliative context may affect the mortality of the operatively treated population. This retrospective cohort study aimed to determine whether the operatively treated geriatric hip fracture population would have a lower in-hospital mortality rate and fewer postoperative complications after the introduction of NOM within a palliative care context for patients with very limited life expectancy. (2) Methods: Data from 1 February 2019 to 1 February 2022 of patients aged 70 years or older were analyzed to give a comparison between patients before and after implementation of NOM within a palliative care context. (3) Results: Comparison between 550 patients before and 485 patients after implementation showed no significant difference in in-hospital or 1-year mortality rates (2.9% vs. 1.4%, p = 0.139; 22.4% vs. 20.2%, p = 0.404, respectively). Notably, post-implementation, fewer patients had prior dementia diagnoses (15% vs. 21%, p = 0.010), and intensive care unit admissions decreased (3.5% vs. 1.2%, p = 0.025). (4) Conclusions: The implementation of NOM within a palliative care context did not significantly reduce mortality or complications. However, NOM within palliative care is deemed a more patient-centered approach for geriatric hip fracture patients with very limited life expectancy. [ABSTRACT FROM AUTHOR]
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- 2024
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19. Triangular fibrocartilage complex injury: outcomes of operative and non‐operative management.
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Onggo, James, Walsh, Kieran, Darcy, Genevieve, Nambiar, Mithun, Mahendru, Gautam, Hui, Cathryn, Pennington, Richard, and Babazadeh, Sina
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MAGNETIC resonance imaging , *SURGICAL pathology , *SMOKING cessation , *NATURAL history , *PAIN measurement - Abstract
Objective: The prevalence TFCC injuries has increased over time. However, there remains a lack of understanding of its natural history. Along with the paucity of evidence on treatment options, there is lack of consensus on how best to manage them. This is a retrospective study with subgroup cohort analysis, examining variables and management options associated with patient‐reported disability and pain. Methods: Patients from a metropolitan health network who have been referred for Magnetic Resonance Imaging (MRI) of the wrist between 2010 and 2019 and identified to have TFCC injury, were followed up to determine patient‐reported outcomes. Disability of arm shoulder and hand scores (DASH) and visual assessment pain scale (VAS) were used to measure disability and pain respectively. An 'excellent' DASH and VAS scores were defined as ≤10 and ≤2, respectively. Results: One hundred and twenty‐four patients met the inclusion criteria and consented to participate in this study. There were 53 patients with excellent DASH score, 95 excellent VAS score and 51 excellent outcomes at mean follow‐up of 75.5 months (Range: 5–402.8 months). Concomitant pathology and surgical management were less likely to have excellent DASH and VAS scores, while traumatic aetiology and smoking were less likely to have excellent VAS score. Age was not predictive of excellent DASH or VAS score. Conclusions: Surgical management of TFCC injuries were associated with worse outcomes than if they were left alone. Smoking cessation is a patient‐modifiable risk factor that may help improve outcomes. [ABSTRACT FROM AUTHOR]
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- 2024
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20. Operative versus non-operative treatment of extra-articular distal humeral shaft fractures: a retrospective comparative study evaluating clinical and radiological outcomes.
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Korman, Avi, Aframian, Arash, and Domos, Peter
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CONSERVATIVE treatment , *FRACTURE healing , *FRACTURE fixation , *FUNCTIONAL assessment , *TREATMENT effectiveness , *RETROSPECTIVE studies , *ORTHOPEDIC apparatus , *ELBOW fractures , *ORTHOPEDIC surgery , *HUMERAL fractures , *COMPARATIVE studies , *RANGE of motion of joints - Abstract
Purpose: There is limited evidence for comparing operative and non-operative management of closed, extra-articular distal humeral shaft fractures. This study aims to evaluate these outcomes. Methods: A comparative retrospective study was performed for patients who underwent either operative fixation or conservative management with a humeral brace, with clinical and radiological outcomes at minimum 2-year follow-up. Results: Forty-two patients with median 4.6 years follow-up were included; 24 had surgical fixation and 18 were managed with humeral brace. Assessment of clinical and radiological outcomes demonstrated few statistically significant functional differences between the two groups. Surgical patients achieved faster union for non-comminuted fractures. All patients maintained functional range of motion, with similar complication rates. Conclusion: This study suggests that similar outcomes can be achieved with both managements, though faster union times may be seen in the operative group. Further studies are recommended to evaluate the impact of fracture comminution causing delayed unions. [ABSTRACT FROM AUTHOR]
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- 2024
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21. A systematic review of the treatment of distal humerus fractures in older adults: A comparison of surgical and non-surgical options.
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Stoddart, Michael T., Panagopoulos, Georgios N., Craig, Richard S., Falworth, Mark, Butt, David, Rudge, Will, Higgs, Deborah, and Majed, Addie
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HUMERAL fractures , *HEMIARTHROPLASTY , *OLDER people , *ELBOW fractures , *FRACTURE fixation - Abstract
Background: Fractures of the distal humerus are a common fragility fracture in older adults. The purpose of this study was to systematically review the literature to produce pooled estimates of the outcomes of treatment using total elbow arthroplasty (TEA), open reduction and locking plate fixation (ORIF), hemiarthroplasty or with conservative management. Methods: A systematic review of PUBMED and EMBASE databases was conducted for studies reporting outcomes of intra-articular fractures in older adults. Data extracted included patient-reported outcome measures as well as clinical outcomes including ROM, adverse events and all-cause reoperation rates. Results: Forty-eight studies met the inclusion criteria and included 1838 acute, intra-articular distal humeral fractures. There was no clinically important difference in patient-reported pain and function measured on the Mayo Elbow Performance Score (TEA = 89.3 (SD 20.0), Hemi = 88.4 (SD 10.6), internal fixation = 85.0 (SD 14.7), non-operative = 85.1 (SD 11.0)). Discussion: Each of the treatment modalities studies resulted in a reasonable level of elbow function. The included studies were largely non-comparative and at considerable risk of bias. As elbow replacement surgery becomes centralised in the UK, there is a real need for high-quality comparative research studies to inform practice. [ABSTRACT FROM AUTHOR]
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- 2024
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22. Non-operative management of terrible triad injuries of the elbow; not so terrible?
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Baker, Megan, Eyre-Brook, Alistair, Gokaraju, Kishan, Jones, Valerie, Thyagarajan, David, Ali, Amjid, and Booker, Simon
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ELBOW injuries , *RADIUS fractures , *PATIENT preferences - Abstract
Introduction: Terrible triad injuries (TTIs) of the elbow have traditionally been reported to have poor outcomes, hence requiring surgical stabilisation. We identified and reviewed patients with TTIs treated non-operatively within our department. Methods: We retrospectively reviewed patients with TTI treated non-operatively with standardised elbow-instability rehabilitation from 2010 to 2020. We used Mason and Morrey classifications for radial head and coronoid fractures, respectively. Non-operative indications included a congruent joint on CT, significant co-morbidities pre-disposing to high-risk surgery and/or patient preference. Outcomes included Oxford Elbow Score (OES), ROM and complications. Results: Nineteen patients were included (mean age 49; 37% female). At an average of 6 years (range 2–11 years) post-treatment, mean OES was 46 ± 7. At last clinic review, mean 6 months (2–15), average ROM was 131 ± 11° flexion, 8 ± 10° extension, 85 ± 12° supination and 85 ± 13° pronation. One patient required arthrolysis and another had an incongruent ulnohumeral joint which developed clicking with a functional ROM. Conclusion: Our report suggests non-operatively managed and appropriately rehabilitated TTI injuries can achieve good function and ROM. We recommend conservative management as a viable option in cases with joint congruency and no mechanical block in patients with significant co-morbidities or those refusing surgery but patients must be assessed on a case-by-case basis. [ABSTRACT FROM AUTHOR]
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- 2024
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23. Short‐ and long‐term outcomes of acute diverticulitis in patients with transplanted kidneys.
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Nantais, Jordan, Baxter, Nancy N., Saskin, Refik, Calzavara, Andrew, and Gomez, David
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DIVERTICULITIS , *KIDNEY transplantation , *KIDNEYS , *DIVERTICULOSIS , *COMPETING risks - Abstract
Aim: The safety of nonoperative treatment for patients with transplanted kidneys who develop acute diverticulitis is unclear. Our primary aim was to examine the long‐term sequelae of nonoperative management in this group. Method: We performed a population‐based retrospective cohort study using linked administrative databases housed at ICES in Ontario, Canada. We included adult (≥18 years) patients admitted with acute diverticulitis between April 2002 and December 2019. Patients with a functioning kidney transplant were compared with those without a transplant. The primary outcome was failure of conservative management (operation, drainage procedure or death due to acute diverticulitis) beyond 30 days. The cumulative incidence function and a Fine–Grey subdistribution hazard model were used to evaluate this outcome accounting for competing risks. Results: We examined 165 patients with transplanted kidneys and 74 095 without. Patients with transplanted kidneys were managed conservatively 81% of the time at the index event versus 86% in nontransplant patients. Short‐term outcomes were comparable, but cumulative failure of conservative management at 5 years occurred in 5.6% (95% CI 2.3%–11.1%) of patients with transplanted kidneys versus 2.1% (95% CI 2.0%–2.3%) in those without. Readmission for acute diverticulitis was also higher in transplanted patients at 5 years at 16.7% (95% CI 10.1%–24.7%) versus 11.6% (95% CI 11.3%–11.9%). Adjusted analyses showed increased failure of conservative management [subdistribution hazard ratio (sHR) 3.24, 95% CI 1.69–6.22] and readmissions (sHR 1.55, 95% CI 1.02–2.36) for patients with transplanted kidneys. Conclusion: Most patients with transplanted kidneys are managed conservatively for acute diverticulitis. Although long‐term readmission and failure of conservative management is higher for this group than the nontransplant population, serious outcomes are infrequent, substantiating the safety of this approach. [ABSTRACT FROM AUTHOR]
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- 2024
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24. Frequency of splenectomy for pediatric splenic injury in Brazil: a retrospective analysisResearch in context
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Luiza Telles, Ayla Gerk, Madeleine Carroll, Matheus Daniel Faleiro, Thais Barbosa de Oliveira, Abbie Naus, Roseanne Ferreira, Fabio Botelho, Joaquim Bustorff-Silva, David P. Mooney, and Julia Ferreira
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Spleen ,Trauma ,Pediatric ,Non-operative ,Conservative ,Surgery ,Public aspects of medicine ,RA1-1270 - Abstract
Summary: Background: Non-operative management for pediatric blunt splenic injury is well established in high-income countries, leading to a low splenectomy rate in hemodynamically stable children. Splenectomy rate became a quality indicator for Trauma Center verification utilized by the American College of Surgeons Committee on Trauma. However, data on splenectomy rate in children from countries with different income levels, such as Brazil, remain limited. This study aimed to assess the post-traumatic splenectomy rate among Brazilian children over the past decade and the relation with local resources. Methods: Data on pediatric splenic injuries and splenectomies from 2008 to 2019, including patient age and admitting service (adult or pediatric), were obtained from FioCruz database, a public, free, cloud-based platform that offers extensive national health data. The regional numbers of pediatric surgeons, pediatric intensive care unit (PICU) beds, and computed tomography scanners were obtained from Brazilian national databases. A national analysis of splenectomy rate by year and service of admission and an analysis of splenectomy rate by the level of regional resources, the number of pediatric surgeons, PICU beds, and computed tomography scanners was performed. Findings: 4061 children were hospitalized with a splenic injury, and 2287 (51.8%) of them underwent splenectomy, unchanged over time. 76.8% were male and 23.1% female patients with splenic injury. Mean age was 11.61 years old. The odds of splenectomy was 14.77 times higher for pediatric patients admitted under adult surgical service compared to pediatric service (OR = 14.77, 95% CI 11.75–18.56, p
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- 2024
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25. Do We Ever Need to Fix Clavicle Fractures in Adolescents?
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Lim KBL, Olandres RA, Cheow X, Thng M, Teo NMHZ, Pereira N, Chan PXE, and Lee NKL
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clavicle fracture ,non-operative ,displacement ,shortening ,Orthopedic surgery ,RD701-811 - Abstract
Introduction: Clavicle fractures in adults are increasingly being treated by surgical fixation following reports of symptomatic non-union, malunion and poor functional outcome with conservative treatment. This has led to a similar trend in the management of clavicle fractures in adolescents. This study aims to evaluate the outcome and complications of non-operatively treated clavicle fractures in adolescents. Materials and methods: This is a retrospective, single institution study on adolescents aged 13-17 years who sustained a closed, isolated clavicle fracture, between 19972015. Clinical records were reviewed for demographic information, injury mode, time to radiographic fracture union, time to re-attainment of full shoulder range of motion (ROM), and time to return to full activities and sports. Complications and fracture-related issues were recorded. Radiographs were analysed for fracture location, displacement and shortening. Results: A total of 115 patients (98 males, 17 females; mean age:13.9 ± 0.89 years) were included for study. 101 (88%) sustained a middle-third fracture while the remainder sustained a lateral-third fracture. A total of 96 (95%) of the middle-third fractures were displaced, and 12 (86%) of the lateral-third fractures were displaced. All displaced fractures in this study had shortening. Sports-related injuries and falls accounted for 68 (59%) and 34 (30%) of the cases respectively. Overall, the mean time to radiographic fracture union was 7.8 ± 4.35 weeks; there were no cases of nonunion. Full shoulder ROM was re-attained in 6.6 ± 3.61 weeks, and full activities and sports was resumed in 11.4 ± 4.69 weeks. There were 5 cases of re-fracture and a single case of intermittent fracture site pain. Conclusion: Clavicle fractures in adolescents can and should be treated non-operatively in the first instance with the expectation of good outcomes in terms of time for fracture union, reattainment of shoulder full range of motion, and return to activities. Surgical stabilisation should be reserved for cases for which there is an absolute indication.
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- 2023
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26. S.P.O.R.R.T.—A Comprehensive Approach to the Assessment and Non-Operative Management of Overuse Knee Conditions in Youth Athletes.
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Davis, Jacob, Doyle, Bridget, Ishii, Haruki, and Jayanthi, Neeru
- Abstract
Purpose of Review: The evaluation of a young athlete with an overuse injury to the knee involves a comprehensive approach. There are a number of elements to consider including assessments of skeletal maturity (biologic maturation), workload (training load + competition load), sport specialization status, and biomechanics. The type of injury and treatment, as well as future prognosis, may be influenced by these and other factors. Recent Findings: Calculating the percentage of predicted adult height (PPAH) is a valuable tool in assessing overuse injury patterns and diagnoses in youth athletes. Modifiable and non-modifiable overuse injury risk factors require monitoring from clinicians as young athletes mature and develop over time. Training and rehabilitation programs should be adapted to account for these. Summary: In this manuscript, we seek to introduce a novel, comprehensive approach: S.P.O.R.R.T. (Skeletal Maturity, Prior Injury Risk, One Sport Specialization, Rehabilitation, Return to Play, Training Recommendations) (Fig. 1). Overuse, non-traumatic injuries to the knee in youth athletes will be presented in a case-based and evidence-based model to provide a framework for a comprehensive approach to the assessment and treatment of youth athletes with overuse injuries. [ABSTRACT FROM AUTHOR]
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- 2023
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27. Updates in the Management of Complex Liver Trauma
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Coccolini, Federico, Tartaglia, Dario, Guelfi, Riccardo, Cremonini, Camilla, Cicuttin, Enrico, Chiarugi, Massimo, Aseni, Paolo, editor, Grande, Antonino Massimiliano, editor, Leppäniemi, Ari, editor, and Chiara, Osvaldo, editor
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- 2023
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28. Treatment of humeral shaft fractures with different treatment methods: a network meta-analysis of randomized controlled trials
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Hao Qiu, Yuting Liu, Yu Chen, Zheng Weng, Dun Liu, Jing Dong, and Minpeng Lu
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Non-operative ,Open reduction and plate osteosynthesis ,Minimally invasive plate osteosynthesis ,Intramedullary nail ,Humeral shaft fracture ,Network meta-analysis ,Diseases of the musculoskeletal system ,RC925-935 - Abstract
Abstract Purpose Humeral shaft fractures (HSFs) can be treated non-operatively (Non-OP), with open reduction and plate osteosynthesis (ORPO), minimally invasive plate osteosynthesis (MIPO), or with intramedullary nails (IMN). However, the best treatment for HSFs still remains controversial.We performed a network meta-analysis to explore which should be the best method for HSFs. Methods The computerized search had been conducted on electronic databases PubMed, EMBASE, Cochrane Library, and Medline from the establishment of the database to the end of December 2022. The quality evaluation of the included literature had been completed by Review Manager (version 5.4.1). Stata 17.0 software (Stata Corporation, College Station, Texas, USA)was used for network meta-analysis.We included randomized controlled trials (RCTs) comparing different treatments to treating HSFs. Results The pairwise comparison results demonstrated that there was no statistical difference between IMN, MIPO, Non-OP, and ORPO in terms of radial nerve injury and infection, and Non-OP presented significantly more nonunion than ORPO, IMN, and MIPO. However, no statistically significant difference between ORPO, IMN, and MIPO was discovered. The results of the network meta-analysis displayed that surface under the cumulative ranking curve (SUCRA) probabilities of IMN, MIPO, Non-OP, and ORPO in radial nerve injury were 46.5%, 66.9%, 77.3%, and 9.3%, respectively, in contrast, that in infection were 68.6%, 53.3%, 62.4%, and 15.4%, respectively, and that in nonunion were 51.7%, 93.1%, 0.7%, and 54.5%, respectively. Conclusion We came to the conclusion that MIPO is currently the most effective way to treat HSFs. Trial registration Name of the registry: Prospero, 2. Unique Identifying number or registration ID: CRD42023411293.
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- 2023
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29. Conservative management a safer option in high-grade renal injuries: Our institutional experience
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Periasamy Ponnusamy, Senthilkumar Poovathai, Rajkumar Ramakrishnan, and Vinayak Sangreshi
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renal injury ,exploration ,conservative ,non-operative ,nephrectomy ,Medicine - Abstract
Background: Renal injuries constitute around 1–5% of all trauma associated injuries. In present era, there has been a focus toward conservative management for blunt renal injuries. Advancement in radiographic injury grading, improved hemodynamic monitoring systems, valid renal injury grading systems allows successful non-operative management for renal preservation even in cases of Grades IV and V. Aims and Objectives: The aim of our study was to assess outcomes of patients managed conservatively (non-operatively) for high-grade blunt renal injury at our center. The objective of this study is to assess whether high-grade renal injuries can be managed by conservative management successfully or not. Materials and Methods: The study conducted in a retrospective manner using hospital records of the past 2 years. Thirty patients with blunt renal injuries were included in the study and were categorized based on the American association for the surgery of trauma (2018 revised) injury grading. These management strategies were analyzed in terms of “failure of conservative management,” complications, and need for adjuvant procedures. Statistical data analysis was done using Microsoft Excel (2019) software. Results: Thirty patients were included in the study with a mean age of years. Out of the total 30 patients, 17 had Grade I–III injuries, and 13 had Grade IV. All the Grade I–III patients were managed conservatively and required no adjunctive procedures. 10 out of 13 cases of Grade IV injuries underwent non-operative management. Complications included urinary tract infection (5), persistent hematuria (3), hypertension (1), urinoma (2), and ileus (1). All complications were of Clavien Dindo classification of grade 1–2. Conclusion: Grade IV blunt renal injuries can be managed conservatively if the patient is hemodynamically stable.
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- 2023
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30. Choice of topical substances in the conservative management of Exomphalos – A systematic review.
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Goneidy, Ayman and Saxena, Amulya K.
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UMBILICAL hernia , *POVIDONE-iodine , *MERCURY poisoning , *CONSERVATIVES , *HUMAN abnormalities - Abstract
Aim: Exomphalos is a congenital anomaly found in 1/4500 newborns. Choice of non‐operative management of exomphalos major unamenable to primary repair is controversial. This study aims at reviewing conservative management modalities and compare outcomes and complications. Methods: A systematic review was performed according to PRISMA guidelines of all English publications in MEDLINE and EMBASE databases. Search words were exomphalos OR omphalocoele AND conservative OR non‐operative AND management. Studies were scrutinised for patient demographics, co‐morbidities, mode of treatment, time to full feeds, time to full epithelialisation, length of stay, complications and mortality. Studies not specifically describing mode of management and/or describing primary or staged surgical repairs were excluded. Results: Initial search resulted in 1243 studies. Forty‐two studies were deemed suitable offering 822 patients for analysis after excluding duplicates and non‐eligible studies. Management methods varied including painting with Alcohol, Mercurochrome, silver products, Povidone Iodine, honey and other materials. Mortality was mostly due to associated anomalies. There was mixed reporting of alcohol, silver, Povidone Iodine and mercury toxicity as well as infection during the course of treatment. Conclusion: This report has recognised the variations in topical substances employed for conservative management with no clear consensus. Reports on safety of different methods remain unclear. [ABSTRACT FROM AUTHOR]
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- 2023
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31. Non-operative Treatment Options for Osteoarthritis in the Hip.
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Nicholas, Erin, Cheng, Jennifer, and Moley, Peter J.
- Abstract
With the increased disability associated with osteoarthritis (OA) progression, and the significant socioeconomic burden of joint replacement surgeries, there is a need for more reliable conservative treatments for patients presenting with hip OA. Most studies of OA treatments involve the knee. We conducted a literature search and reviewed non-operative hip OA treatment recommendations by the Osteoarthritis Research Society International, the American College of Rheumatology, American Academy of Orthopedic Surgeons, and European Alliance of Associations for Rheumatology, as well as Cochrane Reviews. Non-steroidal anti-inflammatory drugs and corticosteroid injections are the most supported and recommended options for hip OA; other medications with potential benefits for short-term pain relief include acetaminophen and tramadol. Most societies recommend against the use of glucosamine, typical opioids, and viscosupplementation injections. Platelet-rich plasma has potential benefits, but evidence of its effectiveness is incomplete. Further research is needed to better inform and guide clinicians who create treatment plans for patients with symptomatic hip OA. [ABSTRACT FROM AUTHOR]
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- 2023
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32. Closed reduction of dorsally displaced distal radius fractures in the elderly provided improved final radiographic results
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Sondre Stafsnes Hassellund, Ingrid Oftebro, John Haakon Williksen, Endre Søreide, Jan Erik Madsen, and Frede Frihagen
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Distal radius fracture ,Elderly ,Treatment ,Non-operative ,Closed reduction ,Malunion ,Orthopedic surgery ,RD701-811 ,Diseases of the musculoskeletal system ,RC925-935 - Abstract
Abstract Background Recent guidelines recommend non-operative treatment as primary treatment in elderly patients with displaced distal radius fractures. Most of these fractures are closely reduced. We aimed to evaluate the radiological results of closed reduction and casting of dorsally displaced distal radius fractures in patients 65 years or older. Methods A total of 290 patients treated during the years 2015, 2018 and 2019 in an urban outpatient fracture clinic with complete follow-up at least 5 weeks post-reduction were available for analysis. Closed fracture reduction was performed by manual traction under hematoma block. A circular plaster of Paris cast was used. Radiographs pre- and post-reduction and at final follow-up were analyzed. Results Mean age was 77 years (SD 8) and 258 (89%) were women. Dorsal tilt improved from mean 111° (range 83–139) to 89° (71–116) post-reduction and fell back to mean 98° (range 64–131) at final follow-up. Ulnar variance was 2 mm ((-1)-12) pre-reduction, 0 mm ((-3)-5) post-reduction and ended at mean 2 mm (0–8). Radial inclination went from 17° ((-6)-30) to 23° (SD 7–33), and then back to 18° (0–32) at final follow-up. 41 (14%) patients had worse alignment at final follow-up compared to pre-reduction. 48 (17%) obtained a position similar to the starting point, while 201 (69%) improved. Fractures with the volar cortex aligned after reduction retained 0.4 mm (95% Confidence Interval (CI) 0.1 to 0.7; p = 0,022) more radius length during immobilization. In a regression analysis, less ulnar variance in initial radiographs (OR 1.8 (95% CI 1.4 to 2.3) per mm, p
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- 2023
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33. Non-operative management for osteochondral lesions of the talus: a systematic review of treatment modalities, clinical- and radiological outcomes.
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Buck, Tristan M. F., Lauf, Kenny, Dahmen, Jari, Altink, J. Nienke, Stufkens, Sjoerd A. S., and Kerkhoffs, Gino M. M. J.
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OSTEOCHONDRITIS , *ANKLE joint , *MAGNETIC resonance imaging , *COMPUTED tomography , *CONSERVATIVE treatment - Abstract
Purpose: The purpose of the present study was to assess the overall clinical success rate of non-operative management for osteochondral lesions of the talus (OLT). Methods: A literature search was conducted in the PubMed (MEDLINE), COCHRANE and EMBASE (Ovid) databases. Clinical success rates per separate study were calculated at the latest moment of follow-up and were defined as successful when a good or excellent clinical result at follow-up was reported in a qualitative manner or when a post-operative American Orthopaedic Foot and Ankle Society (AOFAS) score at or above 80 was reached. When clinical outcomes were based on other clinical scoring systems, outcomes reported as good or excellent were considered as clinical success. Studies methodologically eligible for a simplified pooling method were combined to calculate an overall pooled clinical success rate. Radiological changes over the course of conservative treatment were assessed either considering local OLT changes and/or overall ankle joint changes. Results: Thirty articles were included, including an overall of 868 patients. The median follow-up of the included studies was 37 months (range: 3–288 months). A simplified pooling method was possible among 16 studies and yielded an overall pooled clinical success rate of 45% (95% CI 40–50%). As assessed with plain radiographs, progression of ankle joint osteoarthritis was observed in of 9% (95% CI 6–14%) of the patients. As assessed through a Computed Tomography (CT) scan, focal OLT deterioration was observed in 11% (95% CI 7–18%) of the patients. As assessed with a Magnetic Resonance Imaging (MRI) scan, focal OLT deterioration was observed in 12% (95% CI 6–24%) of the patients. An unchanged lesion was detected on plain radiographs in 53% (48/91; CI 43–63%), 76% (99/131; 95% CI 68–82%) on a CT scan and on MRI in 84% (42/50; 95% CI 71–92%) of the patients. Conclusion: The current literature on non-operative management of OLTs is scarce and heterogeneous on indication and type of treatment. Promising clinical results are presented but need to interpreted with caution due to the heterogeneity in indication, duration and type of treatment. Further studies need to focus on specific types on conservative management, indications and its results. Level of evidence: Systematic review, Level IV. [ABSTRACT FROM AUTHOR]
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- 2023
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34. Physiotherapy Rehabilitation Post Patellar Dislocation (PRePPeD)—protocol for an external pilot randomised controlled trial and qualitative study comparing supervised versus self-managed rehabilitation for people after acute patellar dislocation.
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Forde, Colin, Costa, Matthew L., Cook, Jonathan A., Tutton, Elizabeth, Appelbe, Duncan, Franssen, Marloes, Barker, Rupert, and Keene, David J.
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YOUNG adults , *HOME rehabilitation , *REHABILITATION , *PHYSICAL therapy , *TRIALS (Law) , *QUALITATIVE research - Abstract
Background: Patellar dislocations mainly affect adolescents and young adults. After this injury, patients are usually referred to physiotherapy for exercise-based rehabilitation. Currently, limited high-quality evidence exists to guide rehabilitation practice and treatment outcomes vary. A full-scale trial comparing different rehabilitation approaches would provide high-quality evidence to inform rehabilitation practice. Whether this full-scale trial is feasible is uncertain: the only previous trial that compared exercise-based programmes in this patient population had high loss to follow-up. This study aims to assess the feasibility of conducting a future full-scale trial comparing the clinical and cost-effectiveness of two different rehabilitation approaches for people with an acute patellar dislocation. Methods: Two-arm parallel external pilot randomised controlled trial and qualitative study. We aim to recruit at least 50 participants aged ≥ 14 years with an acute first-time or recurrent patellar dislocation from at least three English National Health Service hospitals. Participants will be randomised 1:1 to supervised rehabilitation (four to six, one-to-one, physiotherapy sessions of advice and prescription of tailored progressive home exercise over a maximum of 6 months) or self-managed rehabilitation (one physiotherapy session of self-management advice, exercise, and provision of self-management materials). Pilot objectives are (1) willingness to be randomised, (2) recruitment rate, (3) retention, (4) intervention adherence, and (5) intervention and follow-up method acceptability to participants assessed through one-to-one semi-structured interviews (maximum 20 participants). Follow-up data will be collected 3, 6, and 9 months after randomisation. Quantitative pilot and clinical outcomes will be numerically summarised, with 95% confidence intervals generated for the pilot outcomes using Wilson's and exact Poisson methods as appropriate. Discussion: This study will assess the feasibility of conducting a full-scale trial comparing supervised versus self-managed rehabilitation for people after acute first-time or recurrent patellar dislocation. This full-scale trial's results would provide high-quality evidence to guide rehabilitation provision for patients with this injury. Trial registration: ISRCTN registry ISRCTN14235231. Registered on 09 August 2022. [ABSTRACT FROM AUTHOR]
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- 2023
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35. No evidence exists on outcomes of non-operative management in patients with femoroacetabular impingement and concomitant Tönnis Grade 2 or more hip osteoarthritis: a scoping review.
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Andronic, Octavian, Claydon-Mueller, Leica Sarah, Cubberley, Rachael, Karczewski, Daniel, Lu, Victor, and Khanduja, Vikas
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HIP osteoarthritis , *YOUNG adults , *HYALURONIC acid , *ORTHOPEDIC braces , *SECONDARY analysis , *INJECTIONS , *INTRA-articular injections - Abstract
Purpose: The purpose of this scoping review was to assess the outcomes of all the non-operative modalities of management for femoroacetabular impingement (FAI) and concomitant osteoarthritis (OA) Tönnis Grade 2 or more. Methods: A systematic search of PubMed was performed from inception to December 1st 2021 for literature on outcomes of non-operative management strategies for young adults with symptomatic FAI using the PRISMA Extension for Scoping Reviews guidelines. Cohorts investigating FAI and concomitant hip OA Tönnis Grade 2 or more were considered eligible. Studies not written in English or German, below level 4 evidence, and reviews were excluded. A secondary analysis for FAI without OA stratification was conducted after the initial screening to allow identification of available non-operative interventions. Results: No study reported outcomes separately for non-operative management of FAI with Tönnis Grade 2 OA or more and as such, did not fulfil the inclusion criteria. A secondary analysis included 24 studies that reported on outcomes for non-operative interventions for FAI irrespective of the degree of degeneration. Three studies investigated the efficacy of hyaluronic acid injection, 5 reports investigated corticosteroid injections, 2 studies evaluated the outcomes of hip bracing and 16 studies included a physiotherapy programme. Associations between the aforementioned interventions were analysed. There is level I evidence supporting the efficacy of activity modification and hip-specific physiotherapy for FAI and mild OA. Core-strengthening exercises are prevalent amongst successful regimens in the literature. Contradictory evidence questions the efficacy of hip bracing even for short-term outcomes. Corticosteroid injections have mostly failed in intention-to treat analyses but may be valuable in delaying the need for surgery; further studies are warranted. Reports on outcomes following hyaluronic acid injections are contradictory. Conclusion: No evidence exists on outcomes following non-operative management of FAI with concomitant Tönnis Grade 2 or more OA of the hip. Further studies are required and should explore the non-operative interventions that were employed for FAI and milder OA. There is strong evidence for a hip-specific physiotherapy program including activity modification and core strengthening exercises. Adjunct interventions such as corticosteroid injections and NSAID consumption may be valuable in delaying the need for surgery. Level of evidence: Level IV. [ABSTRACT FROM AUTHOR]
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- 2023
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36. Conservative management a safer option in high-grade renal injuries: Our institutional experience.
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Ponnusamy, Periasamy, Poovathai, Senthilkumar, Ramakrishnan, Rajkumar, and Sangreshi, Vinayak
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BLUNT trauma ,URINARY tract infections ,GLEASON grading system ,WOUNDS & injuries ,HEMODYNAMIC monitoring ,TRAUMA surgery - Abstract
Background: Renal injuries constitute around 1-5% of all trauma associated injuries. In present era, there has been a focus toward conservative management for blunt renal injuries. Advancement in radiographic injury grading, improved hemodynamic monitoring systems, valid renal injury grading systems allows successful non-operative management for renal preservation even in cases of Grades IV and V. Aims and Objectives: The aim of our study was to assess outcomes of patients managed conservatively (non-operatively) for high-grade blunt renal injury at our center. The objective of this study is to assess whether high-grade renal injuries can be managed by conservative management successfully or not. Materials and Methods: The study conducted in a retrospective manner using hospital records of the past 2 years. Thirty patients with blunt renal injuries were included in the study and were categorized based on the American association for the surgery of trauma (2018 revised) injury grading. These management strategies were analyzed in terms of "failure of conservative management," complications, and need for adjuvant procedures. Statistical data analysis was done using Microsoft Excel (2019) software. Results: Thirty patients were included in the study with a mean age of years. Out of the total 30 patients, 17 had Grade I-III injuries, and 13 had Grade IV. All the Grade I-III patients were managed conservatively and required no adjunctive procedures. 10 out of 13 cases of Grade IV injuries underwent non-operative management. Complications included urinary tract infection (5), persistent hematuria (3), hypertension (1), urinoma (2), and ileus (1). All complications were of Clavien Dindo classification of grade 1-2. Conclusion: Grade IV blunt renal injuries can be managed conservatively if the patient is hemodynamically stable. [ABSTRACT FROM AUTHOR]
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- 2023
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37. Successful non-operative treatment of eruptive keratoacanthomas refractory to excision
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Seger, Edward W, Tarantino, Isadore S, Neill, Brett C, and Wang, Ting
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keratoacanthoma ,non-operative ,intralesional ,5-fluorouracil ,excision - Abstract
Keratoacanthomas are rapidly growing neoplasms of squamous epithelium. Despite their benign nature, they are often difficult to distinguish from squamous cell carcinoma and require excision. In cases in which excision is not successful or not desired, intralesional treatments may be considered. However, limited research exists on individual therapeutic efficacy. We present a 68-year-old man who developed multiple eruptive keratoacanthomas around the wound edge of a previous keratoacanthoma excision. Considering previous excisional failure, intralesional 5-fluorouracil was used as a treatment modality. Injections every 3-4 weeks over a course of 12 weeks induced clinical keratoacanthoma clearance with excellent cosmetic results. This case showcases that weekly intralesional 5-fluorouracil injections, as was the standard mode of treatment in previous case reports, may not be necessary. This less frequent injection strategy is more convenient for the patient and may lead to fewer treatments and less medication necessary. Although a case-by-case basis is needed for any alternative approach to keratoacanthoma treatment, this report is useful for the practicing clinician in showing that 5-fluorouracil may be efficacious in these difficult-to-treat patients.
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- 2020
38. Closed reduction of dorsally displaced distal radius fractures in the elderly provided improved final radiographic results.
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Hassellund, Sondre Stafsnes, Oftebro, Ingrid, Williksen, John Haakon, Søreide, Endre, Madsen, Jan Erik, and Frihagen, Frede
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CONFIDENCE intervals ,ORTHOPEDIC casts ,JOINT dislocations ,REGRESSION analysis ,TREATMENT effectiveness ,ORTHOPEDIC traction ,FRACTURE fixation ,RESEARCH funding ,DESCRIPTIVE statistics ,ODDS ratio ,DISTAL radius fractures ,BONE fractures ,OLD age - Abstract
Background: Recent guidelines recommend non-operative treatment as primary treatment in elderly patients with displaced distal radius fractures. Most of these fractures are closely reduced. We aimed to evaluate the radiological results of closed reduction and casting of dorsally displaced distal radius fractures in patients 65 years or older. Methods: A total of 290 patients treated during the years 2015, 2018 and 2019 in an urban outpatient fracture clinic with complete follow-up at least 5 weeks post-reduction were available for analysis. Closed fracture reduction was performed by manual traction under hematoma block. A circular plaster of Paris cast was used. Radiographs pre- and post-reduction and at final follow-up were analyzed. Results: Mean age was 77 years (SD 8) and 258 (89%) were women. Dorsal tilt improved from mean 111° (range 83–139) to 89° (71–116) post-reduction and fell back to mean 98° (range 64–131) at final follow-up. Ulnar variance was 2 mm ((-1)-12) pre-reduction, 0 mm ((-3)-5) post-reduction and ended at mean 2 mm (0–8). Radial inclination went from 17° ((-6)-30) to 23° (SD 7–33), and then back to 18° (0–32) at final follow-up. 41 (14%) patients had worse alignment at final follow-up compared to pre-reduction. 48 (17%) obtained a position similar to the starting point, while 201 (69%) improved. Fractures with the volar cortex aligned after reduction retained 0.4 mm (95% Confidence Interval (CI) 0.1 to 0.7; p = 0,022) more radius length during immobilization. In a regression analysis, less ulnar variance in initial radiographs (OR 1.8 (95% CI 1.4 to 2.3) per mm, p < 0.001) and lower age (OR 1.06 (95% CI 1.02 to 1.09) per year, p < 0.003) protected against loss of reduction. Conclusion: Subsequent loss of reduction after initial closed reduction was seen in most distal radius fractures. Reduction improved overall alignment in 2/3 of the patients at final follow-up. An aligned volar cortex seemed to protect partially against loss of radial length. [ABSTRACT FROM AUTHOR]
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- 2023
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39. Fixation of Proximal Third Humeral Shaft Fractures in Older Patients.
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Quarcoopome, Jared, Adam, John, Baljer, Bence, Nagi, Ahmed, Eardley, Will, and McVie, James L.
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LENGTH of stay in hospitals ,PATIENT aftercare ,UNUNITED fractures ,FRAIL elderly ,HUMERAL fractures ,PHYSICAL therapy ,RETROSPECTIVE studies ,ACQUISITION of data ,DISEASE incidence ,RISK assessment ,SEVERITY of illness index ,FRACTURE fixation ,MEDICAL records ,CASE studies ,LONGITUDINAL method ,OUTPATIENT services in hospitals ,DISEASE risk factors ,OLD age - Abstract
Background: Humeral shaft fractures occur frequently in older patients. The more proximal end of the shaft is prone to non-union when compared with more distal fractures. We provide an overview of several key features of this significant patient group. Method: Our institutional fracture database was searched for all cases of proximal third humeral shaft fractures in patients over 60 years of age. Retrospective evaluation of patient demographics, management, length of stay and incidence of non-union was performed. Results: 75 patients (61 female) were analysed. 33 patients were 'frail' (Clinical Frailty Scores of >4). Non-union occurred in 19 of 45 non-surgically treated fractures and in 1 of 37 cases treated surgically. Mean length of stay was 5.9 days (non-operative) and 6.6 days (operative). Proximal extension into the humeral head is common. Conclusion: Non-surgical management of proximal third humeral shaft fractures is associated with an increased risk of non-union. We detail an operative technique and case example supporting early fixation of displaced proximal third humeral shaft fractures in older patients that can be utilized for both primary and delayed fixation. In view of the significant association of non-union a well-constructed prospective cohort study with outcome assessment would be of value to further characterize this emerging injury population. Level of Evidence: Level IV, retrospective case series [ABSTRACT FROM AUTHOR]
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- 2023
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40. Kidney and uro-trauma: WSES-AAST guidelines.
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Coccolini, Federico, Moore, Ernest, Kluger, Yoram, Biffl, Walter, Leppaniemi, Ari, Matsumura, Yosuke, Kim, Fernando, Peitzman, Andrew, Fraga, Gustavo, Sartelli, Massimo, Ansaloni, Luca, Augustin, Goran, Kirkpatrick, Andrew, Abu-Zidan, Fikri, Wani, Imitiaz, Weber, Dieter, Pikoulis, Emmanouil, Larrea, Martha, Arvieux, Catherine, Manchev, Vassil, Reva, Viktor, Coimbra, Raul, Khokha, Vladimir, Mefire, Alain, Ordonez, Carlos, Chiarugi, Massimo, Machado, Fernando, Sakakushev, Boris, Matsumoto, Junichi, Maier, Ron, di Carlo, Isidoro, and Catena, Fausto
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Adult ,Bladder ,Classification ,Conservative ,Embolization ,Endovascular trauma management ,Flow chart ,Guidelines ,Kidney ,Non-operative ,Operative ,Pediatric ,Stenting ,Surgery ,Trauma ,Ureter ,Urethra ,Urogenital ,Urological ,Acute Kidney Injury ,General Surgery ,Guidelines as Topic ,Hemodynamics ,Humans ,Injury Severity Score ,Kidney ,Triage ,Urinary Tract - Abstract
Renal and urogenital injuries occur in approximately 10-20% of abdominal trauma in adults and children. Optimal management should take into consideration the anatomic injury, the hemodynamic status, and the associated injuries. The management of urogenital trauma aims to restore homeostasis and normal physiology especially in pediatric patients where non-operative management is considered the gold standard. As with all traumatic conditions, the management of urogenital trauma should be multidisciplinary including urologists, interventional radiologists, and trauma surgeons, as well as emergency and ICU physicians. The aim of this paper is to present the World Society of Emergency Surgery (WSES) and the American Association for the Surgery of Trauma (AAST) kidney and urogenital trauma management guidelines.
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- 2019
41. Duodeno-pancreatic and extrahepatic biliary tree trauma: WSES-AAST guidelines.
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Coccolini, Federico, Kobayashi, Leslie, Kluger, Yoram, Moore, Ernest, Ansaloni, Luca, Biffl, Walt, Leppaniemi, Ari, Augustin, Goran, Reva, Viktor, Wani, Imitiaz, Kirkpatrick, Andrew, Abu-Zidan, Fikri, Cicuttin, Enrico, Fraga, Gustavo, Ordonez, Carlos, Pikoulis, Emmanuil, Sibilla, Maria, Maier, Ron, Matsumura, Yosuke, Masiakos, Peter, Khokha, Vladimir, Mefire, Alain, Ivatury, Rao, Favi, Francesco, Manchev, Vassil, Sartelli, Massimo, Machado, Fernando, Matsumoto, Junichi, Chiarugi, Massimo, Arvieux, Catherine, Catena, Fausto, and Coimbra, Raul
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Adult ,Ampulla ,Bile duct ,Biliary tree ,Classification ,Conservative ,Duodenum ,Endoscopic retrograde cholangiopancreatography (ERCP) ,Endoscopy ,Guidelines ,Injury ,Non-operative ,Operative ,Pancreas ,Pediatric ,Surgery ,Trauma ,Abdominal Injuries ,Bile Ducts ,Extrahepatic ,Duodenum ,Focused Assessment with Sonography for Trauma ,General Surgery ,Guidelines as Topic ,Humans ,Pancreas ,Tomography ,X-Ray Computed ,Trauma Centers ,Triage ,Ultrasonography - Abstract
Duodeno-pancreatic and extrahepatic biliary tree injuries are rare in both adult and pediatric trauma patients, and due to their anatomical location, associated injuries are very common. Mortality is primarily related to associated injuries, but morbidity remains high even in isolated injuries. Optimal management of duodeno-bilio-pancreatic injuries is dictated primarily by hemodynamic stability, clinical presentation, and grade of injury. Endoscopic and percutaneous interventions have increased the ability to non-operatively manage these injuries. Late diagnosis and treatment are both associated to increased morbidity and mortality. Sequelae of late presentations of pancreatic injury and complications of severe pancreatic trauma are also increasingly addressed endoscopically and with interventional radiology procedures. However, for moderate and severe extrahepatic biliary and severe duodeno-pancreatic injuries, immediate operative intervention is preferred as associated injuries are frequent and commonly present with hemodynamic instability or peritonitis. The aim of this paper is to present the World Society of Emergency Surgery (WSES) and American Association for the Surgery of Trauma (AAST) duodenal, pancreatic, and extrahepatic biliary tree trauma management guidelines.
- Published
- 2019
42. Treatment options in extra-articular distal radius fractures: a systematic review and meta-analysis.
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Van Oijen, Guido W., Van Lieshout, Esther M. M., Reijnders, Maarten R. L., Appalsamy, Anand, Hagenaars, Tjebbe, and Verhofstad, Michael H. J.
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MEDICAL databases ,META-analysis ,MEDICAL information storage & retrieval systems ,CONFIDENCE intervals ,ORTHOPEDIC implants ,SYSTEMATIC reviews ,FRACTURE fixation ,DESCRIPTIVE statistics ,QUALITY assurance ,DATA analysis software ,MEDLINE ,RADIUS fractures - Abstract
Purpose: This systematic literature review aimed to make a detailed overview on the clinical and functional outcomes and to get insight into the possible superiority of a treatment method for extra-articular distal radius fractures. Methods: Embase, Medline, Cochrane Library, Web of Science, and Google Scholar were searched for studies describing treatment results. Five treatment modalities were compared: plaster cast immobilization, K-wire fixation, volar plating, external fixation, and intramedullary fixation. Results: Out of 7,054 screened studies, 109 were included in the analysis. Overall complication rate ranged from 9% after plaster cast treatment to 18.5% after K-wire fixation. For radiographic outcomes, only volar tilt in the plaster cast group was lower than in the other groups. Apart from better grip strength after volar plating, no clear functional differences were found across treatment groups. Conclusion: Current literature does not provide uniform evidence to prove superiority of a particular treatment method when looking at complications, re-interventions, and long-term functional outcomes. [ABSTRACT FROM AUTHOR]
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- 2022
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43. Management of Partial-Thickness Distal Biceps Tears
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Uyeki, Colin L., Archambault, Simon D., Slater, Maria G., Muench, Lukas N., Mazzocca, Augustus D., Romeo, Anthony A., editor, Erickson, Brandon J., editor, and Griffin, Justin W., editor
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- 2021
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44. Principles of Treatment of Pelvic Ring Injuries
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Lindahl, Jan, Gänsslen, Axel, Gänsslen, Axel, editor, Lindahl, Jan, editor, Grechenig, Stephan, editor, and Füchtmeier, Bernd, editor
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- 2021
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45. Non-operative management of blunt liver trauma in Qena University Hospital
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Asmaa Gaber Rizk, Nezar Abdel Raouf Abo Halawa, Ahmed Abdelmoneim Abdelrasheed, and Andrew Roshdy Arteen Arteen
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non-operative ,liver ,blunt trauma ,Medicine - Abstract
Background: Even though it is in a protective location, the abdominal organ that suffers damage the most frequently is the liver. A revolution in the management of acute abdominal organ injuries has occurred in recent decades, with major advancements in outcomes and a shift away from required surgery. Objectives: To present our experience in non-operative management of blunt liver trauma patients in Qena University Hospital. Patients and methods: This prospective cohort study was conducted at general surgery department. The study included 50 patients admitted to the emergency department with blunt liver trauma. The duration of the study ranged from august 2021 to july 2022 . Results: Treatment success distributions of the studied group show that the majority had Treatment success (86.0). 7 cases died (14.0%) , the cause of death was sepsis in 4 cases (8.0%) , and hemorrhagic shock in 3 cases (6.0%) and transfer to surgical treatment before death Conclusion; With a high success rate even in the treatment of high-grade liver lesions and a low and acceptable morbidity rate, our protocol offers a safe and effective therapeutic approach for both moderate and severe liver damage.
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- 2023
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46. Determinants of success associated with vacuum bell treatment of pectus excavatum.
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Toselli, Luzia, Chinni, Emilio, Nazar-Peirano, Maximiliano, Vallee, Maxroxia, Sanjurjo, Daniela, Martinez, Jorge, and Bellia-Munzon, Gaston
- Abstract
• Although useful, vacuum bell treatment of pectus excavatum is not effective in all cases. • An initial pectus depth of 1.8 cm and a 12-month duration of treatment were the best thresholds for prediction of success. Patients with satisfactory outcomes had a significantly lower pectus depth by 9 months of treatment. We explored determinants of success in a large cohort of patients with pectus excavatum submitted to vacuum bell treatment and compared groups with satisfactory versus unsatisfactory outcomes. Retrospective case-control study in a single center between May 2013 and January 2020, including patients with pectus excavatum treated with vacuum bell. We classified patients according to their status at closure of data registry (surveillance; withdrawal; complete correction; failure) and according to Obermeyer's classification of degrees of pectus excavatum correction. Determinants of success were calculated using receiver operating characteristic curves. Overall, 186 patients were included. Complete correction was achieved by 17% of the cases, while 45% remained under surveillance. Failure rates were low (n = 9; 5%), whereas withdrawal rates were 34%. Based on Obermeyer's classification of degree of excavation correction, 35% had excellent/good, 25% fair, and 40% poor/worse results. When comparing patients with good/excellent results with those with unsatisfactory results, patients with good/excellent results had a longer treatment duration [19.0 (13.0; 28) months vs. 13.0 (6.5; 22.5) months, p <0.0001], and lower initial pectus depth [1.6 (1.2; 2.0) cm, vs. 2.0 (1.5; 2.6) cm, p = 0.001]. Using ROC curves, the best determinants of success were an initial pectus depth ≤ 1.8 cm and a length of treatment > 12 months. One-third of patients in treatment with a vacuum bell achieved excellent or good outcomes in our cohort. Determinants of success included an initial pectus depth of 1.8 cm or less and a minimum length of treatment of 12 months. retrospective comparative study III [ABSTRACT FROM AUTHOR]
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- 2022
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47. 1.7 cm elongated Achilles tendon did not alter walking gait kinematics 4.5 years after non-surgical treatment.
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Kastoft, Rasmus, Barfod, Kristoffer, Bencke, Jesper, Speedtsberg, Merete B., Hansen, Sanja Bay, and Penny, Jeannette Ø.
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Purpose: The aim of the present study was to evaluate Achilles tendon length after non-surgical treatment of acute Achilles tendon rupture (aATR), and to evaluate indirect effects of possible persistent elongation on kinematics. Methods: The study was performed as a cross-sectional study based on a population of patients from an RCT regarding non-operative treatment of aATR. Thirty-seven patients out of the 56 in the original RCT participated with at a follow up of 4–5 years after aATR. Primary outcome was Achilles tendon elongation. Additional outcomes were Achilles tendon resting angle (ATRA), calf circumference, passive ankle plantar and dorsiflexion and loading pattern. Foot pressure mapping was performed to measure plantar loading distribution pattern; medial and lateral forefoot peak pressure, heel peak pressure, medial versus lateral loading pattern and timing of heel lift during roll over process. The healthy leg was used as a control. Results: The injured Achilles tendon was significantly elongated by 1.7 (SD 1.6) cm compared to the non-injured leg. A slight delay of 2.6% (SD 6.0) was measured in heel lift in the injured side compared to the non-injured leg. We found no significant difference in forefoot peak pressure, medial and lateral peak pressure as well as heel peak pressure, and no correlation was found between Achilles tendon length and pressure measurements. Finally, dorsiflexion was 1.9°(SD1.28) larger, ATRA 8.1°(SD6.7) larger, and calf circumference 1.6 cm (SD1.1) lower on the injured leg. Conclusion: The Achilles tendon was 1.7 cm elongated 4.5 years after the initial injury and significant changes in ATRA, calf circumference and passive dorsiflexion was present. Except for a slight delay in heel lift-off, kinematics during walking was symmetrical between injured and healthy leg, even with an elongated tendon on the injured leg. The clinical relevance of the Achilles tendon elongation is uncertain. Level of evidence: II. Clinical trials identifier: NCT02760784. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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48. Minimal intervention dentistry for managing carious lesions into dentine in primary teeth: an umbrella review.
- Author
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BaniHani, A., Santamaría, R. M., Hu, S., Maden, M., and Albadri, S.
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MINIMALLY invasive dentistry ,DECIDUOUS teeth ,DENTAL caries ,DENTIN ,TOPICAL drug administration ,DENTAL acid etching ,PULPOTOMY ,PIT & fissure sealants (Dentistry) - Abstract
Purpose: This umbrella review systematically appraised published systematic reviews on Minimal Intervention Dentistry interventions carried out to manage dentine carious primary teeth to determine how best to translate the available evidence into practice, and to provide recommendations for what requires further research. Method: An experienced information specialist searched MEDLINE, Embase, Cochrane Database of Systematic Reviews, Epistemonikos, Joanna Briggs Institute Database of Systematic Reviews and Implementation Reports, and the NIHR Journals Library. In addition, the PROSPERO database was searched to identify forthcoming systematic reviews. Searches were built around the following four concepts: primary teeth AND caries/carious lesion AND Minimal Intervention Dentistry AND systematic review/meta-analysis. Searches were restricted to English language, systematic reviews with/without meta-analyses published between January 2000 and August 2020. Two reviewers independently screened all titles and abstracts. Interventions included involved no dentine carious tissue removal (fissure sealants, resin infiltration, topical application of 38% Silver Diamine Fluoride, and Hall Technique), non-restorative caries control, and selective removal of carious tissue involving both stepwise excavation and atraumatic restorative treatment. Systematic reviews were selected, data extracted, and risk of bias assessed using ROBIS by two independent reviewers. Studies overlap was calculated using corrected covered area. Results: Eighteen systematic reviews were included in total; 8 assessed the caries arresting effects of 38% Silver Demine Fluoride (SDF), 1 on the Hall Technique (HT), 1 on selective removal of carious tissue, and eight investigated interventions using atraumatic restorative treatment (ART). Included systematic reviews were published between 2006 and 2020, covering a defined time frame of included randomised controlled trials ranging from 1969 to 2018. Systematic reviews assessed the sealing efficacy of fissure sealants and resin infiltration in carious primary teeth were excluded due to pooled data reporting on caries arrest in both enamel and outer third of dentine with the majority of these carious lesions being limited to enamel. Therefore, fissure sealants and resin infiltration are not recommended for the management of dentinal caries lesions in primary teeth. Topical application of 38% SDF showed a significant caries arrest effect in primary teeth (p < 0.05), and its success rate in arresting dental caries increased when it was applied twice (range between 53 and 91%) rather than once a year (range between 31 and 79%). Data on HT were limited and revealed that preformed metal crowns placed using the HT were likely to reduce discomfort at time of treatment, the risk of major failure (pulp treatment or extraction needed) and pain compared to conventional restorations. Selective removal of carious tissue particularly in deep carious lesions has significantly reduced the risk of pulp exposure (77% and 69% risk reduction with one-step selective caries removal and stepwise excavation, respectively). ART showed higher success rate when placed in single surface compared to multi-surface cavities (86% and 48.7–88%, respectively, over 3 years follow-up). Conclusion: Minimal Intervention Dentistry techniques, namely 38% SDF, HT, selective removal of carious tissue, and ART for single surface cavity, appear to be effective in arresting the progress of dentinal caries in primary teeth when compared to no treatment, or conventional restorations. There is clear need to increase the emphasis on considering these techniques for managing carious primary teeth as a mainstream option rather than a compromise option in circumstances where the conventional approach is not possible due to cooperation or cost. [ABSTRACT FROM AUTHOR]
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- 2022
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49. Splenic trauma: WSES classification and guidelines for adult and pediatric patients
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Coccolini, Federico, Montori, Giulia, Catena, Fausto, Kluger, Yoram, Biffl, Walter, Moore, Ernest E, Reva, Viktor, Bing, Camilla, Bala, Miklosh, Fugazzola, Paola, Bahouth, Hany, Marzi, Ingo, Velmahos, George, Ivatury, Rao, Soreide, Kjetil, Horer, Tal, ten Broek, Richard, Pereira, Bruno M, Fraga, Gustavo P, Inaba, Kenji, Kashuk, Joseph, Parry, Neil, Masiakos, Peter T, Mylonas, Konstantinos S, Kirkpatrick, Andrew, Abu-Zidan, Fikri, Gomes, Carlos Augusto, Benatti, Simone Vasilij, Naidoo, Noel, Salvetti, Francesco, Maccatrozzo, Stefano, Agnoletti, Vanni, Gamberini, Emiliano, Solaini, Leonardo, Costanzo, Antonio, Celotti, Andrea, Tomasoni, Matteo, Khokha, Vladimir, Arvieux, Catherine, Napolitano, Lena, Handolin, Lauri, Pisano, Michele, Magnone, Stefano, Spain, David A, de Moya, Marc, Davis, Kimberly A, De Angelis, Nicola, Leppaniemi, Ari, Ferrada, Paula, Latifi, Rifat, Navarro, David Costa, Otomo, Yashuiro, Coimbra, Raul, Maier, Ronald V, Moore, Frederick, Rizoli, Sandro, Sakakushev, Boris, Galante, Joseph M, Chiara, Osvaldo, Cimbanassi, Stefania, Mefire, Alain Chichom, Weber, Dieter, Ceresoli, Marco, Peitzman, Andrew B, Wehlie, Liban, Sartelli, Massimo, Di Saverio, Salomone, and Ansaloni, Luca
- Subjects
Physical Injury - Accidents and Adverse Effects ,Childhood Injury ,Emergency Care ,Patient Safety ,Pediatric ,Hematology ,Injuries and accidents ,Abdominal Injuries ,Adult ,Conservative Treatment ,Guidelines as Topic ,Hemodynamics ,Humans ,Spleen ,Wounds and Injuries ,Trauma ,Classification ,Guidelines ,Embolization ,Surgery ,Non-operative ,Conservative - Abstract
Spleen injuries are among the most frequent trauma-related injuries. At present, they are classified according to the anatomy of the injury. The optimal treatment strategy, however, should keep into consideration the hemodynamic status, the anatomic derangement, and the associated injuries. The management of splenic trauma patients aims to restore the homeostasis and the normal physiopathology especially considering the modern tools for bleeding management. Thus, the management of splenic trauma should be ultimately multidisciplinary and based on the physiology of the patient, the anatomy of the injury, and the associated lesions. Lastly, as the management of adults and children must be different, children should always be treated in dedicated pediatric trauma centers. In fact, the vast majority of pediatric patients with blunt splenic trauma can be managed non-operatively. This paper presents the World Society of Emergency Surgery (WSES) classification of splenic trauma and the management guidelines.
- Published
- 2017
50. Comparative effectiveness of treatment options for displaced midshaft clavicle fractures: a systematic review and network meta-analysis
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John R. Martin, Patrick E. Saunders, Mark Phillips, Sean M. Mitchell, Michael D. Mckee, Emil H. Schemitsch, and Niloofar Dehghan
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midshaft clavicle fractures ,network meta-analysis ,non-operative ,compression plate ,reconstruction plate ,intramedullary nail ,Orthopedic surgery ,RD701-811 - Abstract
Aims: The aims of this network meta-analysis (NMA) were to examine nonunion rates and functional outcomes following various operative and nonoperative treatments for displaced mid-shaft clavicle fractures. Methods: Initial search strategy incorporated MEDLINE, PubMed, Embase, and the Cochrane Library for relevant randomized controlled trials (RCTs). Four treatment arms were created: nonoperative (NO); intramedullary nailing (IMN); reconstruction plating (RP); and compression/pre-contoured plating (CP). A Bayesian NMA was conducted to compare all treatment options for outcomes of nonunion, malunion, and function using the Disabilities of the Arm Shoulder and Hand (DASH) and Constant-Murley Shoulder Outcome scores. Results: In all, 19 RCTs consisting of 1,783 clavicle fractures were included in the NMA. All surgical options demonstrated a significantly lower odds ratio (OR) of nonunion in comparison to nonoperative management: CP versus NO (OR 0.08; 95% confidence interval (CI) 0.04 to 0.17); IMN versus NO (OR 0.07; 95% CI 0.02 to 0.19); RP versus NO (OR 0.07; 95% CI: 0.01 to 0.24). Compression plating was the only treatment to demonstrate significantly lower DASH scores relative to NO at six weeks (mean difference -10.97; 95% CI -20.69 to 1.47). Conclusion: Surgical fixation demonstrated a lower risk of nonunion compared to nonoperative management. Compression plating resulted in significantly less disability early after surgery compared to nonoperative management. These results demonstrate possible early improved functional outcomes with compression plating compared to nonoperative treatment. Surgical fixation of mid-shaft clavicle fractures with compression plating may result in quicker return to activity by rendering patients less disabled early after surgery. Cite this article: Bone Jt Open 2021;2(8):646–654.
- Published
- 2021
- Full Text
- View/download PDF
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