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6 results on '"Noemí, Mengual Macenlle"'

1. Factores que condicionan la pérdida de control al reducir escalones terapéuticos en el tratamiento del asma moderada-grave en la práctica clínica habitual: estudio español multicéntrico

Author

Martínez-Moragón, E., Delgado, J., Mogrovejo, S., Fernández-Sánchez, T., Jesús, Jiménez López, Ángel, Moscardó Orenes Miguel, Patricia, Prieto Montaño, Miguel, Torrecillas Toro, Begoña, Cueva Oliver, Ángel, Ferrer Torres, Purificación, González Delgado, Wilfox, Jiménez Rodríguez Teodorikez, Brian, Vila Auli, José, Zapata Yebenes Juan, Teresa, Audicana Berasategui María, Marta, Frias Jiménez, Nieves, Hurtado de Mendoza Ruibio, Marta, Velasco Azagra, Antonio, Álvarez Fernández Jose, Sara, Acero Sainz, Rosa, Blanco González M., Estela, Gómez Nieves María, Diego, Aisa Carpio, Núria, Angrill Sellés, Cristina, Berastegui García, Astrid, Crespo Lessmann, David, De La Rosa Carrillo, Jordi, Juanola Pla, Alejandra, López Giraldo, Olga, Luengo Sánchez, Carlos, Martínez Rivera, Pilar, Martínez Olondris, Xavier, Muñoz Gall, Ester, Pinto Nogués, Francisco, Planas Coimerma, Karina, Portillo Carroz, Antoni, Riba Blanch, Luisa, Rivera Ortún M., Dan, Sánchez Berenguer, Joan, Serra Batlles, Pere, Serra Mitjà, Ana, Sogo Sagardía, Lorena, Soto Retes, Joan, Valldeperas Combas, Xavier, Vila Giralte, Ignacio, Ansotegui Zubeldia, Ignacio, Antepara Ercoreca, Miguel, Herrerías Peña, Milagros, Iriberri Pascual María, Carmen, Jaca Michelena, Adolfo, Lahuerta Castro, Amaia, Laita Legarreta, Paula, Losada Llorente, Joaquina, Prieto Prieto, Vanessa, Zorrilla Lorenzo, Lidia, Alonso Gil, Pablo, García Muñoz Juan, Marisa, Marcos Durantez, Teresa, Peña Miguel, Tahar, Ahmida, Isabel, Alvarado Izquierdo María, Michael, Alwakil Olbah, Aurelio, Arnedillo Muñoz, Ignacio, García Núñez, Diego, Gutiérrez Fernández, Antonio, Letran Camacho, Luis, Fernández Pellon, Maria, Morchon Miguel Eva, Félix, Ortiz Portal, Isabela, Raducan, Antonio, Royo Prats Juan, Dolores, Salvador Segarra María, Frederic, Tatay Soler, Alberto, Levy Naon, Pedro, Galindo Bonilla, Luis, Gil Muñoz Francisco, Patricia, Mata Calderón, Manuel, Entrenas Costa Luis, Marina, Blanco Aparicio, Manuel, García Pazos Jose, Vanessa, García Paz, Francisco-Javier, González Barcala, Pilar, Iriarte Sotes, Jorge, Marcos Rodríguez Pedro, Fernando, Molina Nieto, Ramón, Nuñez Orjales, Carracedo, Sevillano Martín, Juan, Suárez Antelo, Julia, Tábara Rodríguez, Santiago, Aparicio Español, Carlos, Sabadell Nieto, Gladis, Sabater Talaverano, Mar, Escribano Rodríguez M., Fernando, Florido López José, Ángeles, Lara Jiménez María, José, Rojas Vílchez María, Susana, Chic Palacín, Silvia, Dorronsoro Quintana, Antonio, Navarro Echeverria Jose, Eduardo, Figueroa de la Guardia, Belén, Hinojosa Jara, Victoria, Moreno García, Lucía, Valverde Vazquez, Joaquín, Cegoñino de Sus, Santonio, Compaired Villa Jose, Alfonso, Almagro López Juan, Eduardo, Arcalá Campillo, María, Cruz Molina Jose, Dolores, Soto Venegas Antonia, Patricia, Benito Martínez, Begoña, Blanco Reinosa, Beatriz, Fernández Parra, Domingo, Fernández García, Virginia, Serrano Gutiérrez, Adolfo, Velez Ruiz de Lobera, Silvia, Lara Alcon, Francisco, Carballada González, Teresa, González Fernández, Joaquín, Martín Lázaro, Noemí, Mengual Macenlle, Soledad, Alonso Viteri, Darío, Antolín Amerigo, Irina, Bobolea, Puerto, Cano Aguirre M. del, Remedios, Cardenas Contreras, Fernando, Carrillo Arias, Mercedes, Cimarra Álvarez, Belén, De Higes Martínez Eva, Magdalena, Díaz Campos Rocío, Mar, Gandolfo Cano María del, Leticia, García Rodríguez, Andrés, García Romero de Tejada Jose, Eloina, González Mancebo, Emma, González Seco, Fernando, González Torralba, Aythamy, Henríquez Santana, Lys, Herráez Herrera Pilar de, Ruth, Herrero Mosquete María, Pedro, Landete Rodríguez, Belén, López-Muñiz Ballesteros, Ester, Mohedano Vicente, Beatriz, Morales Chacón, Antonio, Moreno Fernández, Esther, Muñoz García, Elena, Ojeda Castillejo, Fernando, Pedraza Serrano, Yesenia, Peña Acevedo Acevedo, Raquel, Pérez Rojo, Natividad, Quílez Ruiz-Rico, Ángela, Ramos Pinedo, Beatriz, Rodríguez Jiménez, Mercedes, Rodríguez Rodríguez, Ana, Rosado Ingelmo, Antonio, Ruiz Peña, José, Sánchez González María, Jesús, Trujillo Trujillo María, Laura, Vázquez Fuertes, Concepción, Vila Albelda, Alexandra, Yago Meniz, Ismael, Aguilar Perez Grovas Ricardo, José, Alcázar Ramírez Alcázar Ramírez, Manuel, Barceló Muñoz José, Miguel, Bentabol Manzanares, Gustavo, De Luiz Martínez, Francisco, Linde de Luna, Alfonso, Miranda Paez, Ezequiel, Ortega Sáenz de Tejada, Alicia, Padilla Galo, Manuel, Pérez Estrada Cornejo, Carmen, Soria Esojo, Francisco, Abellán Alemán Ángel, Consuelo, Alcalde Rumayor María, Rubén, Andújar Espinosa, Roberto, Bernabeu Mora, Javier, Campano Lancharro Francisco, Tamara, Gutiérrez Urra, Sonia, Herrero Martín, Alfredo, Resano Lizaldre, and Raquel, Dacal Quintas

Published
2020
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2. Prognostic Indices and Mortality Prediction in COPD Caused by Biomass Smoke Exposure

Author

Olalla Castro-Añón, Rafael Golpe, Pilar Sanjuán-López, Esteban Cano-Jiménez, Luis A. Pérez-de-Llano, and Noemí Mengual-Macenlle

Subjects
Male, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Multivariate analysis, Comorbidity, Severity of Illness Index, Tobacco smoke, Pulmonary Disease, Chronic Obstructive, Predictive Value of Tests, Cause of Death, Smoke, Internal medicine, Severity of illness, medicine, Humans, Biomass, Intensive care medicine, Aged, Retrospective Studies, Aged, 80 and over, Air Pollutants, COPD, business.industry, Smoking, Age Factors, Environmental Exposure, Middle Aged, Prognosis, medicine.disease, Obstructive lung disease, respiratory tract diseases, ROC Curve, Air Pollution, Indoor, Area Under Curve, Predictive value of tests, Female, business, Body mass index
Abstract

Little is known about survival and prognostic factors in chronic obstructive pulmonary disease (COPD) due to biomass smoke exposure (BS-COPD). (1) To determine the value of two indices of COPD severity: BODEx (body mass index, obstruction, dyspnea, and previous severe exacerbations) and Global Initiative for Chronic Obstructive Lung Disease (GOLD) categories system (ABCD) to predict all-cause mortality in BS-COPD, compared with COPD due to tobacco (T-COPD); (2) to verify the usefulness of 2 comorbidity indices, Charlson index and COTE (COPD comorbidity index); and (3) to put side by side the value of these indices. 612 consecutive COPD patients were retrospectively studied. Prognostic factors were evaluated taking into account the exposure to biomass or tobacco smoke. The relative predictive values of the prognostic indices were compared using receiver-operating characteristic analysis. Mortality in the BS-COPD and T-COPD groups was not significantly different, when sex was taken into account. BODEx, Charlson and COTE indices—but not type of exposure—predicted mortality in multivariate analysis. The value of the C-statistic for the BODEx index was not different than that of GOLD ABCD for BS-COPD, but was higher for T-COPD. The discriminatory value of the Charlson index was higher than that of COTE for BS-COPD, but no significant differences were found for T-COPD. Multidimensional indices of COPD severity and comorbidity predict all-cause mortality in BS-COPD. The behavior of the different indices is different for BS-COPD and T-COPD.

Published
2015

3. Joint CHEST-SGP Congress 2017. Basel, Switzerland, 7-9 June 2017: Abstracts

Author

Yeliz Enderle, George D'Souza, Anna-Bettina Haidich, Luisa Bonafé, Alain Tremblay, Elisabeth D. Hasler, Jean Michel Vergnon, Konrad E. Bloch, Philip J. Devereaux, Pilar Sanjuán-López, Chahéra Khouatra, Rafael Golpe, Jürgen Burhenne, Marc Fortin, Samuel V. Kemp, Paul MacEachern, Hans Klose, Hermann Eschenbacher, Christophe von Garnier, Esteban Cano-Jiménez, Priya Patel, Vincent Cottin, Satenik Harutyunova, Silvia Ulrich, Christine Fischer, Sabina Berezowska, Laurent P. Nicod, Olivier Tiffet, Olalla Castro-Añon, Didier Revel, Huan-Zhong Shi, Kazuhiro Yasufuku, Dionisia Michalopoulou, Romain Lazor, Begüm Ergan, Arzu Topeli, Lazaros Sichletidis, Yuan Yang, Benjamin Egenlauf, Hélène Thibault, Srinivas Rajagopala, Uma Devaraj, Ralf Eberhardt, Priya Ramachandran, Luis Pérez-de-Llano, Stéphanie Saxer, Arnaud Patoir, Noemí Mengual-Macenlle, Fabien Forest, Pallav L. Shah, Ya-Lan Liu, Andrea Huppertz, Georgia Karpathiou, Satz Mengensatzproduktion, Frédéric Barbey, Felix J.F. Herth, Ajay M. V. Kumar, Daniela Gompelmann, Werner Druck Medien Ag, Johanna Ohnesorge, Diamantis Chloros, Elaine Dumoulin, Dionisis Spyratos, Irene Martín-Robles, Nicola Benjamin, Christel Tran, Mousa Mobarki, Walter E. Haefeli, Christopher A. Hergott, Chung Chun Tyan, Kasia Czarnecka, Michael Furian, Mouhamad Nasser, Michel Peoc'h, Ekkehard Grünig, and Marios Froudarakis

Subjects
Pulmonary and Respiratory Medicine, 03 medical and health sciences, medicine.medical_specialty, 0302 clinical medicine, business.industry, Physical therapy, Medicine, 030212 general & internal medicine, 030204 cardiovascular system & hematology, business, Joint (geology)
Published
2017

4. Utility of PCR in bronchial aspirate samples for rapid diagnosis of tuberculosis

Author

Lidia Méndez Marote, Noemí Mengual Macenlle, Manuel Lorenzo López Reboiro, Antón Penas Truque, Pilar Sanjuán López, and Luis Pérez de Llano

Subjects
medicine.medical_specialty, Tuberculosis, medicine.diagnostic_test, biology, business.industry, Diagnosis tool, Lung biopsy, biology.organism_classification, medicine.disease, Gastroenterology, Sputum culture, law.invention, Mycobacterium tuberculosis, Bronchoalveolar lavage, Pulmonary tuberculosis, law, Internal medicine, medicine, business, Polymerase chain reaction
Abstract

Introduction: Rapid diagnosis and treatment are important for preventing transmission of Mycobacterium tuberculosis. Objective: To study the yield of polymerase chain reaction (PCR) in samples of bronchial aspirate (BA) for rapid diagnosis of pulmonary tuberculosis (TB). Methods: We retrospectively reviewed TB-suspected patients requiring diagnostic bronchoscopy between 1st February 2012 and 1st October 2013. PCR assay and smear microscopy were performed in BA in all cases. We compared the sensitivity and specificity of both methods for early diagnosis of tuberculosis. Definitive diagnosis of TB was established based on a positive culture for Mycobacterium tuberculosis in respiratory samples (sputum culture, BA, bronchoalveolar lavage) and/or the presence of necrotizing granulomas in lung biopsy and response to treatment of TB. Results: 168 patients were included, 118 men (70.2%). Mean age was 63.6 ± 14.5 years. Eighteen patients (10.7%) were diagnosed with TB. Table 1 shows the results of PCR and smear microscopy in BA in the groups of patients with and without TB The sensitivity and specificity of PCR was 88.8% and 99.3%, respectively. The sensitivity and specificity of smear microscopy was 55.5% and 99.3%, respectively. Conclusions: The sensitivity of PCR for rapid diagnosis of tuberculosis in BA samples was higher than smear microscopy. Including this test as a diagnosis tool in daily clinical practice could be very useful for the early detection of TB.

Published
2015

5. Prognostic value of multidimensional indices in ambulatory COPD patients

Author

Pilar Sanjuán-López, Noemí Mengual-Macenlle, Luis Pérez de Llano, Irene Martín-Robles, and Rafael Golpe

Subjects
Male, medicine.medical_specialty, Copd patients, business.industry, Comorbidity, Prognosis, medicine.disease, Severity of Illness Index, Pulmonary Disease, Chronic Obstructive, Ambulatory, Internal Medicine, Humans, Medicine, Female, business, Intensive care medicine, Value (mathematics), Aged, Retrospective Studies
Published
2015

6. Multivariate analysis in thoracic research

Author

Noemí, Mengual-Macenlle, Pedro J, Marcos, Rafael, Golpe, and Diego, González-Rivas

Subjects
Statistic Corner
Abstract

Multivariate analysis is based in observation and analysis of more than one statistical outcome variable at a time. In design and analysis, the technique is used to perform trade studies across multiple dimensions while taking into account the effects of all variables on the responses of interest. The development of multivariate methods emerged to analyze large databases and increasingly complex data. Since the best way to represent the knowledge of reality is the modeling, we should use multivariate statistical methods. Multivariate methods are designed to simultaneously analyze data sets, i.e., the analysis of different variables for each person or object studied. Keep in mind at all times that all variables must be treated accurately reflect the reality of the problem addressed. There are different types of multivariate analysis and each one should be employed according to the type of variables to analyze: dependent, interdependence and structural methods. In conclusion, multivariate methods are ideal for the analysis of large data sets and to find the cause and effect relationships between variables; there is a wide range of analysis types that we can use.

Published
2014

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