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8 results on '"Nobuyoshi Okumura"'

1. A Software Servo System for VCRs

Author

Yukinori Kishida, Yukihisa Naoe, Kazuo Hayashi, M. Kawabata, and Nobuyoshi Okumura

Subjects
Materials science, business.industry, Computer science, General Engineering, Block diagram, Software performance testing, Servomotor, Servomechanism, law.invention, Software, law, Microcomputer, Embedded system, Software system, business, Videocassette recorder, Computer hardware
Published
1992
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3. The Relationship Between Glucose Tolerance and Pancreatic

Author

Katsumoto Kato, Akira Sakakibara, Takeshi Takei, Yoshihiro Yamazaki, Masayuki Takeichi, Toshiyuki Suzuki, Masao Nakamura, Nobuyoshi Okumura, and Tetsuo Hayakawa

Subjects
Hepatology
Abstract

慢性肝疾患にみられる耐糖能異常の機序を追求する一環として合併する膵内外分泌機能障害の実態を明らかにし,耐糖能との関連性を検討した.慢性肝疾患101例にPancreozymin secretin試験とブドウ糖負荷試験を行い,大多数の例で糖負荷後の血中インスリン反応を,一部の例ではアルギニン静注負荷後の血中インスリン,グルカゴン動態も検討した.膵外分泌機能障害を呈した例は非硬変群の40%,肝硬変群の55%に達したが,その大多数は軽度障害であり,この段階では耐糖能や内分泌機能に対する影響は認められなかった.中等度以上の外分泌機能障害は非硬変の大酒家で多くみられ,耐糖能異常やインスリン低反応,グルカゴン低反応を伴う例が多かった.慢性肝疾患全体としては膵障害は耐糖能異常の発現に著しく関与しているとは言えないが,大酒歴を有する非硬変例で耐糖能低下がみられる時には膵障害の合併も考えて,その検索をすることが大切である.

Published
1978
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5. Plasma pancreatic glucagon in pancreatic and primary diabetes, and liver cirrhosis: Application of a correction to the radioimmunoassay for pancreatic glucagon

Author

Kojiro Gtsuka, Tetsuo Hayakawa, Nobuyoshi Okumura, Takaharu Kondo, Aiji Noda, Kenzo Yasui, and Yuji Nimura

Subjects
Liver Cirrhosis, Male, endocrine system, medicine.medical_specialty, Cirrhosis, Pancreatic glucagon, Total pancreatectomy, Radioimmunoassay, Glucagon, Diabetes mellitus, Internal medicine, Diabetes Mellitus, medicine, Humans, Aged, business.industry, Gastroenterology, Pancreatic Diseases, food and beverages, Glucose Tolerance Test, Middle Aged, Hepatology, medicine.disease, Pancreatic Neoplasms, Endocrinology, Pancreatitis, Interference factor, Chronic Disease, Female, business, hormones, hormone substitutes, and hormone antagonists
Abstract

Evidence is present that plasma contains non-specific factors which interfere with the 30K glucagon assays. A correction can be made for these interference factors because the factors can be quantitated following absorption of glucagon with charcoal-dextran. Using a correction factor the range of fasting plasma immunoreactive glucagon (IRG) in 12 totally pancreatectomized patients was below detectable limit. Fasting levels of IRG were determined on the plasma from 25 liver cirrhotics complicated by abnormal GTT, 13 pancreatic diabetics with chronic calcified pancreatitis (CCP), 25 adult-onset primary diabetics and 25 healthy subjects. When all samples were measured using no correction factor, the mean levels of IRG were 358 +/- 24 (mean +/- SE), 170 +/- 26, 178 +/- 16 and 178 +/- 7 pg/ml, respectively. Using a correction factor the mean level of IRG were 177 +/- 26, 16 +/- 4, 39 +/- 9 and 20 +/- 4 pg/ml, respectively. The mean values of the interference factor were not significantly different among all five groups. During an arginine infusion the interference factor remained unchanged despite an increase in IRG. It is available but not always necessary to apply a correction factor for 30K glucagon radioimmunoassay.

Published
1982
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6. Follow-up study of chronic pancreatitis

Author

Ribun Mizuno, Takaharu Kondo, Kazuhito Ito, Akira Sakakibara, Nobuyoshi Okumura, Satoru Naruse, Tetsuo Hayakawa, Yukio Iinuma, Aiji Noda, and Yoshihiro Yamazaki

Subjects
Adult, Male, medicine.medical_specialty, Alcohol Drinking, Pain relief, Pain, Gastroenterology, Surgical oncology, Internal medicine, medicine, Humans, Glucose tolerance test, medicine.diagnostic_test, business.industry, General surgery, Follow up studies, Calcinosis, Glucose Tolerance Test, Middle Aged, Hepatology, medicine.disease, Dietary Fats, Colorectal surgery, Pancreatitis, Chronic Disease, Female, Cholecystokinin, business, Follow-Up Studies, Abdominal surgery
Abstract

The general profile of pain in the evolution of pancreatitis was analysed in relation to exocrine and endo:rine pancreatic function in 127 patients with primary chronic pancreatitis followed up over 3 years. Pain decreased or disappeared in 67.8% and 55.9% of calcifying and non-calcifying pancreatitis, respectively. While pancreatic exocrine function remained abnormal in spite of an improvement of pain in 72% of 18 patients with calcifying pancreatitis, it improved with the amelioration of pain in 64.0% of 25 patients with non-calcifying pancreatitis during the follow-up period. Alcohol abstinence seems most important for pain relief in patients with non-calcifying pancreatitis but not calcifying pancreatitis. Changes in glucose tolerance test were not related with those in pain. In calcifying pancreatitis, 69.2% of patients with calcifying pancreatitis were diabetic or became so, while 66.7% of patients with non-calcifying pancreatitis remained non-diabetic during the observation period.

Published
1981
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7. Proceedings of the 69th General Meeting from April 11–13, 1983-Osaka, Japan

Author

Yoshihiro Baba, Kunio Nagata, Yoshihisa Tsukada, Rintaro Narisawa, Akira Honma, Shinichi Hirose, Mineo Tomizawa, Toshihiko Ozaki, Fumihiro Ichida, Kenji Tanehiro, Nobuyoshi Kuno, Kumiko Kurimoto, Tetsuo Yokota, Tomoyuki Kano, Tatsuzo Kasugai, Kazuya Ueno, Katsuhide Shimakura, Akira Kakita, Masaaki Kambayashi, Tsuyoshi Takahashi, Eisei Sasaki, Yoichi Kasai, Toshihisa Takahashi, S. Shimaguchi, J. Ariyama, Masatoshi Sumida, Yukihiro Tsuchiya, Masao Ohto, Fumio Asagami, Tadasu Fuji, Norimasa Okabe, Kenji Sakurai, Shuichi Miyakawa, Yuji Horiguchi, Hiroshi Nakano, Yuji Nimura, N. Hayakawa, H. Hasegawa, J. Kamiya, S. Maeda, Y. Iyomasa, Yoshiro Matsumoto, Katsuhiko Sugahara, T. Ida, R. Mashimo, Shu Kou Wen, H. Fujii, S. Wakashiro, G. Isowa, S. Itoh, T. Yamakawa, Hidenori Udaka, Hideyuki Miyamoto, Toshikazu Tamura, Tsutomu Hirai, Osamu Okamura, Nobuhiko Komi, Nobuo Yoshioka, Yoshio Kawamura, Takahiko Kojima, Hitoshi Hachiya, Nobuyoshi Okumura, Kunihiko Suzuki, Toshiyuki Suzuki, Sadasuke Suzuki, Norishige Ozeki, Kazuo Goto, Shigehiro Shiraki, Toshihiko Takeuchi, Atsumasa Yamaguchi, Tadashi Shibue, Yukimitsu Kawaura, Takashi Iwa, Isao Takeda, Satoshi Nakano, Tomoko Kobayashi, Hideo Harada, Tokio Wakabayashi, Norio Sawabu, Yasuo Naito, Saburo Nakazawa, Tomoaki Isawa, Ikuo Tabata, Yuichi Sasaki, Hideaki Yamada, Shunichi Tatsumi, Kenzo Kobayashi, Eitaro Suzuki, Eizo Okamoto, Masakatsu Matsukawa, Toshio Nakanishi, Hiroiku Kawakami, Sotaro Fujimoto, Masatsugu Nakajima, Junichi Sugihara, Yoichi Saitoh, Takashi Matsushiro, Hideyuki Nagashima, Kyoji Yamamoto, Ryuji Nakamura, Junichi Tanaka, Fumito Shimizu, Takashi Toshima, Tuneo Hariu, Takukazu Nagakawa, Noriyoshi Suzuki, Wataru Takahashi, Ikunoshin Uematsu, Toshio Sato, K. Egami, T. Tajiri, N. Aoki, K. Yamaguchi, H. Yamakawa, A. Watanabe, M. Yano, S. Hatta, M. Yoshioka, M. Miki, A. Shirota, Koji Morimoto, Masato Furukawa, Toshinori Nakata, Ryuhei Yamada, Shinichiro Ito, Shigeru Maeda, Toshinori Morinaga, Makota Tanigawa, Toshiyuki Fujio, Hiroshi Inui, Hiroaki Kinoshita, Osamu Yamasaki, Eiichi Nagata, Kazuhiro Hirohashi, null Sakai, Tadahiro Takada, Hideki Yasuda, Makoto Shishikura, Katsuhiro Uchiyama, Yoshifumi Ogura, Ryuji Mizumoto, Kazuomi Nakazawa, Shunichi Sato, Isamu Kaito, Hiroshi Suzuki, Masao Ohtsuki, Yoshio Goto, M. Nomoto, K. Yunoue, K. Soga, F. Ichida, Y. Koike, K. Kiyosawa, Y. Akahane, K. Kamijyo, Y. Suzuki, S. Yamamura, T. Komatsu, A. Nagata, S. Furuta, Shigeki Hayashi, Yasuhiko Ohta, Kenji Fujiwara, Yuzuru Sato, Itsuro Ogata, Katsuyoshi Takatsuki, Shunji Mishiro, Hiroshi Oka, Masaru Furube, Nobuo Yamada, Hisao Shibata, Akitaka Shibuya, Eishi Hijikata, Shigenobu Kokubu, Kohdo Ishii, Haruya Okabe, Kenichi Sasaki, Akira Takada, Jugoro Takeuchi, Yasuyuki Ohta, Tadashi Tsujii, Fumiaki Ikegame, Masashi Unoura, Akihiko Furusawa, Nobuyoshi Tanaka, Yasuhiro Kato, Kenichi Kobayashi, Nobu Hattori, Yukihiko Tameda, Satoshi Kakiuchi, Yoshitane Kosaka, Shigeyoshi Harihara, Sukeo Yamamoto, Gotaro Yamada, Hideo Nagashima, Morikazu Onji, Yoshimasa Yamashita, Norio Horiike, Hirohiko Abe, Kazuhiko Hino, Masaru Kojima, Kazunori Noguchi, Hiromu Ueda, Tomoki Aritaka, Naoto Maruyama, Hitoshi Motoori, Kazuaki Yamauchi, Hiroshi Setoyama, Michio Sata, Yasuhiko Kubo, Kyuichi Tanikawa, Tatsuo Munehisa, Keisuke Nakata, Kenzo Kono, Toyoichi Muro, Akira Sato, Ryuji Furukawa, Nobuko Ishii, Yukio Kusumoto, Toshihiko Koji, Shigenobu Nagataki, Norio Nakao, Kohi Miura, Y. Sato, Y. Ohta, I. Ogata, S. Hayashi, K. Fujiwara, H. Oka, S. Furui, M. Iio, Kenji Ikeda, Eiji Oyake, Kazuo Takeuchi, Hiromitsu Kumada, Masao Nakajima, Akira Yoshiba, Masahiro Irimoto, Toshio Kobayashi, Morio Satoh, Ryusaku Yamada, Haruki Nakatsuka, Kenji Hirai, Masanobu Kumagai, Genjiro Yamaguchi, Masatoshi Tanaka, Masanobu Abe, Keijiro Ando, Yasushi Shingai, Kiwamu Okita, Tadayoshi Takemoto, Kazuo Tarao, Kenichiro Iwamura, Kenji Soga, Minoru Nomoto, Hitoshi Takagi, Takafumi Ichida, Shunsaku Higashi, Takashi Noguchi, Takashi Kanematsu, Kenji Takenaka, Takashi Matsumata, Takashi Sonoda, Toshiya Furuta, Keizo Sugimachi, Kiyoshi Inokuchi, Susumu Yamasaki, Hiroshi Hasegawa, Masatoshi Makuuchi, Yoshimi Nakanishi, Hidekazu Sano, Tetsuro Konno, Fumio Sano, Toshiharu Tsuzuki, Shuhei Iida, Naoki Yamanaka, Keiji Kuwata, Akihiro Toyosaka, Nobutaka Tanaka, Shiro Fujiwara, Hajime Yamazaki, Katsuji Sakai, Tokio Ono, Hiroaki Yamada, Masahiro Tada, Hitoshi Asakura, Kensuke Kobayashi, Tetsuo Morishita, Masaharu Tsuchiya, Nobutaka Sato, Hideo Hiratsuka, N. Ueda, and K. Harada

Subjects
medicine.medical_specialty, business.industry, Internal medicine, Gastroenterology, Library science, Medicine, business
Published
1984
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8. Plasma pancreatic glucagon response to blood glucose in experimental pancreatolithiasis in dogs

Author

Takahisa Kondo, Akira Sakakibara, Nobuyoshi Okumura, Tetsuo Hayakawa, and Aiji Noda

Subjects
Blood Glucose, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Glucagon, Diabetes Mellitus, Experimental, Impaired glucose tolerance, Dogs, Diabetes mellitus, Internal medicine, Internal Medicine, medicine, Animals, Insulin, Ligation, Pancreatic duct, Glucose tolerance test, medicine.diagnostic_test, business.industry, Pancreatic Ducts, medicine.disease, medicine.anatomical_structure, Endocrinology, Glucose, Pancreatitis, Chronic Disease, business, Pancreas
Abstract

In an attempt to study pancreatic A cell function at an early stage of pancreatic diabetes secondary to chronic pancreatitis, both intravenous glucose (0.5 g/kg) and insulin (0.5 U/kg) tolerance tests were performed on seven dogs with pancreatolithiasis and seven normal control dogs. Experimental pancreatolithiasis was produced 12 months after incomplete ligation of the greater pancreatic duct. Impaired glucose tolerance and reduced plasma insulin response to an intravenous glucose load were observed in the calcified group. Pancreatic release of glucagon to insulin-induced hypoglycaemia was diminished, but suppressive response of the hormone to glucose-induced hyperglycaemia was well preserved. These data suggest that the A cell response to hypoglycaemia may be impaired earlier than that to hyperglycaemia in pancreatic diabetes secondary to pancreatolithiasis.

Published
1983

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