28 results on '"Noé GK"'
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2. Der Zusammenhang zwischen Geburtserleben und der Anwendung zertifizierter Schmerzkonzepte in der Geburtshilfe
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Klöpfer, AS, additional, Dagres, T, additional, Suppelna, JP, additional, Noé, GK, additional, Krentel, H, additional, Tempfer, C, additional, and Schiermeier, S, additional
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- 2017
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3. Application of a Three-Port Sealable Morcellation Bag in a Multicenter Setting
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Anapolski, M, primary, Schellenberger, A, additional, Panayotopoulos, D, additional, Schiermeier, S, additional, and Noé, GK, additional
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- 2016
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4. The Laparoscopic Pectopexy (NPP): A New Approach for Apical Prolapse Repair
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Noé, GK, primary
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- 2016
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5. Laparoscopic Native Tissue Repair of the Posterior Compartment
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Noé, GK, primary
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- 2016
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6. Retroperitoneal Para Aortic Lymph Node Dissection
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Noé, GK, primary
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- 2016
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7. Anwendung eines Morcellations-Beutels mit drei verschließbaren Arbeitsöffnungen bei 277 laparoskopischen supracervicalen Hysterektomien: Erste Erfahrungen einer Multicenter-Observationsstudie
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Anapolski, M, primary, Panayotopoulos, D, additional, and Noé, GK, additional
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- 2016
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8. The Use of a Closable Polyurethane Bag for Power Morcellation
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Anapolski, M, primary and Noé, GK, additional
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- 2015
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9. Laparoskopischer paravaginaler „repair“ bei Traktionszystocele – Minimalinvasiver Defektverschluss mittels PP- Netz
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Noé, GK, primary
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- 2008
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10. The Feasibility of Practical Training in Minimally Invasive Surgery at Medical School-A Prospective Study on the Pelvitrainer.
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Ackermann J, Pape J, Vogler F, Pahls J, Baumann J, Holthaus B, Noé GK, Anapolski M, Ruchay Z, Westermann A, Günther V, Andresen K, Allahqoli L, Moawad G, Neymeyer J, Brügge S, Maass N, Mettler L, and Alkatout I
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- Humans, Prospective Studies, Schools, Medical, Feasibility Studies, Minimally Invasive Surgical Procedures, Surgeons, Students, Medical
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Background and Objectives : The acquisition of practical skills at medical school is an important part of the multidimensional education program of future physicians. However, medical schools throughout the world have been slow in incorporating practical skills in their curriculum. Therefore, the aims of the present prospective study were (a) to demonstrate the feasibility of such surgical training, (b) to objectify its benefit in medical education, and (c) to investigate the impact of such training on subsequent career choices. Material and Methods: We introduced a two-day laparoscopy course on the pelvitrainer as part of the curriculum of the gynecological internship of fifth year medical students from 2019 to 2020. The results of the students' training were matched to those of surgeons who completed the same curriculum in a professional postgraduate laparoscopy course from 2017 to 2020 in a comparative study design. Additionally, we performed a questionnaire-based evaluation of the impact of the course on medical education and subsequent career choices directly before and after completing the course. Results: A total of 261 medical students and 206 physicians completed the training program. At baseline, the students performed significantly more poorly than physicians in a median of three of four exercises ( p < 0.001). However, this evened out in the final runs, during which students performed more poorly than physicians only in one exercise and even better than physicians in one. The general integration of surgical training in medical school curricula was rated very low (12.4% on the VAS, IQR 3-16%) despite the high demand for such training. In the survey, the course was deemed very beneficial for medical education (median VAS 80.7%, IQR 73-98%), but did not appear to influence the students' subsequent career preferences. Conclusions: The acquisition of practical surgical skills during medical school is significantly under-represented in many medical faculties. The benefits of such training, as demonstrated in our study, would improve the education of future physicians.
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- 2024
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11. Characterization in respect to degradation of titanium-coated polypropylene surgical mesh explanted from humans.
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Farr NTH, Klosterhalfen B, and Noé GK
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- Humans, Materials Testing, Polypropylenes chemistry, Titanium, Biocompatible Materials chemistry, Surgical Mesh
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Titanium-coated polypropylene (Ti-PP) mesh was introduced in 2002 as a surgical mesh for the treatment of hernias and shortly after for pelvic floor surgery, with the aim of improving biocompatibility when compared to non-titanised/regular PP mesh implants. The application of a titanium coating could also be beneficial to address concerns regarding the exposure of PP in an in vivo environment. Many studies have shown that PP, although it is widely accepted as a stable polymer, is subject to oxidation and degradation, such degradation affects the mechanical behavior, that is, the stiffness and tensile strength of PP mesh. Despite the wide clinical use of Ti-PP surgical meshes, no study has yet investigated the residual material properties post clinical deployment and subsequent explantation. In this study, two explanted Ti-PP mesh samples each having different incorporation durations from two patients were examined. Material analysis conducted within this study includes the following techniques: attenuated total reflectance-Fourier transform infrared spectroscopy (ATR-FTIR), Raman spectroscopy, low voltage - scanning electron microscopy (LV-SEM), backscattered electron (BSE) imaging, energy dispersive X-ray spectroscopy (EDS) and secondary election hyperspectral imaging (SEHI). The hypothesis of this study is that the Ti coating successfully shields the PP mesh from oxidative stress in vivo and thus protects it from degradation. The results of this analysis show for the first time evidence of bulk oxidation, surface degradation, and environmental stress cracking on explanted Ti-PP meshes., (© 2023 The Authors. Journal of Biomedical Materials Research Part B: Applied Biomaterials published by Wiley Periodicals LLC.)
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- 2023
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12. Assessment of the New Acceleromyograph TOF 3D Compared with the Established TOF Watch SX: Bland-Altman Analysis of the Precision and Limits of Agreement between Both Devices-A Randomized Clinical Comparison.
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Soltesz S, Thomas J, Anapolski M, and Noé GK
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The new acceleromyograph TOF 3D was compared with the established TOF Watch SX in patients undergoing elective laparoscopic gynecological surgery. Neuromuscular transmission was assessed by simultaneous recording with both devices. Measurements were performed simultaneously at the left and the right M. adductor pollicis (Group A, 25 patients), or the M. corrugator supercilii (Group CS, 25 patients). The repeatability, time course, and limits of agreement (Bland-Altman) were compared. The primary endpoint was the 90% train-of-four recovery time (TOFR 0.9). Other endpoints included onset time of block, maximum T1 depression, time to 25% T1 recovery, the recovery time course of T1 response, and TOF ratio, respectively. In group CS, the repeatability coefficient of the TOF 3D was lower (4.66 (1.6)) than of the TOF Watch SX (6.02 (1.9); p = 0.026). In group A, the onset of the block was faster when measured by the TOF 3D (98.7 (30) s vs. 112.2 (36) s (mean (SD)); p = 0.032). In group A, time to recovery to a TOFR of 90% was measured earlier by the TOF 3D (bias -0.71 min, limits of agreement from -8.94 to +7.51 min). The TOF 3D provides adequate information with high precision and sensitivity. It is suitable even for measurement sites with small muscle contractions such as the M. corrugator supercilii.
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- 2022
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13. Laparoscopic versus vaginal native tissue repair in combination with pectopexy. Sub-analysis from an international, prospective, and multi-centre study: short term results.
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Noé GK, Barnard A, Spüntrup C, Schiermeier S, Soltécz S, Anapolski M, and Alkatout I
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- Cicatrix, Female, Gynecologic Surgical Procedures methods, Humans, Prospective Studies, Surgical Mesh, Treatment Outcome, Laparoscopy methods, Pelvic Organ Prolapse surgery
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Introduction: The use of mesh for vaginal repairs is currently problematic and as a consequence, there is increased interest in native tissue repair. We describe the follow-up data of a sub-analysis of a prospective and multi-center study focusing on the combination of pectopexy and native tissue repair. Patients were followed up for 12-18 months after surgery (+ SD: 15). Two-hundred and sixty-four patients attended the clinics for physical examination and were integrated into the follow-up. Cystocele repair was performed laparoscopically in 84 patients and vaginally in 52 patients. Posterior repair was performed vaginally in 40 patients and laparoscopically in 53 patients., Results: Clinical success rate, patient recommendations and patient satisfaction rates were similar in both groups. The laparoscopic anterior repair resulted in an 89% cure or anatomical improvement rate; this compared to 94.2% for the vaginal approach. In the posterior group, laparoscopy resulted in a 94.3% cure or improvement rate compared to 97.5% in the second group., Conclusions: The outcomes of both strategies showed satisfactory results in our study. Consequently, surgeons may choose between the two strategies according to their preference and skill. The two approaches only differed with regard to vaginal scarring. We suggest future research investigating the long-term impact of scarring.
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- 2022
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14. Preclinical safety testing and initial experience of a morcellation bag with four sealable ports.
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Anapolski M, Schellenberger A, Alkatout I, Panayotopoulos D, Gut A, Soltesz S, Schiermeier S, Papathemelis T, and Noé GK
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- Female, Humans, Hysterectomy methods, Laparoscopy methods, Leiomyoma surgery, Surgical Instruments adverse effects, Uterus surgery, Morcellation adverse effects, Morcellation methods
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Electromechanical morcellation-so called power morcellation-is a minimally invasive approach to remove bulky lesions such as uterine fibroids. The spread of benign and malignant tissue due to morcellation is a major concern that might limit the use of laparoscopic interventions. We present an in vitro evaluation of the safety characteristics of a four-port endobag with closable trocar sleeves, and describe physical properties of the bag that may or may not allow passage through the hole. In addition, we report our preliminary experience of this tool when used for laparoscopic supracervical hysterectomies. The behavior of the endobag during the extraction process was analyzed by extracting opened and re-sealed bags filled with 20 ml blue dye solution through a wooden template, with incisions measuring 10 to 24 mm. The endobag was used in 50 subtotal hysterectomies during the morcellation procedure. In the in vitro test, no dye loss was recorded for incisions measuring 11-24 mm. The mean force required to pull the bag through the template was inversely proportional to incision size. No bag rupture occurred during the surgical procedures. The mean time taken to prepare the bag for morcellation was 7.1 min (range, 4-14 min), the mean duration of subtotal hysterectomy was 53.4 min (range, 20-194 min). The mean weight of the removed body of the uterus was 113.8 g (range, 13-896 g), the mean weight of tissue and fluid remaining in the bag after morcellation 7.9 g (range, 0-39 g). In the in vitro setting, the improved endobag signifies greater patient safety during bag extraction, along with less tissue traumatization due to a smaller incision in the abdominal wall. The improved ergonomic features of the bag permit the insertion of three trocars in the lower abdomen and avoid closure of unused access ports. Our preliminary experience has shown that the device can be used under routine conditions. Failure rates will be evaluated in future studies., (© 2021. The Author(s).)
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- 2021
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15. Current Role of Hysterectomy in Pelvic Floor Surgery: Time for Reappraisal? A Review of Current Literature and Expert Discussion.
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Noé GK, Barnard A, Schiermeier S, and Anapolski M
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- Female, Humans, Laparoscopy, Vagina surgery, Hysterectomy, Pelvic Floor surgery
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Since hysterectomy could be performed with low risk, it has been part of the standard of surgical prolapse therapy for decades. This has not been scrutinized for a long time. In this review, we describe the development of this issue in recent years. The current literature suggests that hysterectomy requires its own indication. The article describes the various options for a uterine-preserving surgical technique and the available data., Competing Interests: All 4 authors have no conflict of interest regarding the content of the article., (Copyright © 2021 Guenter K. Noé et al.)
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- 2021
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16. Laparoscopic approaches to the retropubic space: three alternatives with anatomical considerations.
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Anapolski M, Alkatout I, Wedel T, Panayotopoulos D, Soltesz S, Schiermeier S, Papathemelis T, and Noé GK
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- Humans, Surgical Instruments, Laparoscopy, Urinary Incontinence, Stress surgery
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Introduction: Many urogynecological and surgical laparoscopic interventions require access to the retropubic space, also known as the space of Retzius. Especially in patients with a history of previous surgery in this area or in general in the lower abdomen, the preparation may be complicated by adhesions and scar tissue. The necessity to combine several laparoscopic procedures in one surgical session may require consideration of the most appropriate way to approach the retropubic space., Material and Methods: We describe and discuss three different options to access the space of Retzius via laparoscopy: the medial transperitoneal, the extraperitoneal and the lateral transperitoneal approach. For all approaches, we used one umbilical trocar and two trocars in the lower abdomen., Results: An algorithm was developed to select the most appropriate access route to the retropubic space, depending on the history of previous surgeries and accompanying interventions., Conclusion: The knowledge of different access routes to the retropubic space offers the possibility of adjusting the surgical procedure to the individual constellation of the patient.
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- 2021
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17. The influence on resection line during supracervical hysterectomy: physiological extension of endometrial cells in the cervix uteri
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Spuentrup C, Wendt E, Banerjee M, Schmitz J, Hellmich M, and Noé GK
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Objective: A straight resection of corpus uteri using the sacrouterine ligament as landmark is a common method during supracervical hysterectomy. Subsequent spotting rates of up to 25% suggest the existence of residual endometrial glands in the remaining cervical tissue, casting doubt on the landmark qualities of the sacrouterine ligament. Fifty-one females who underwent total laparoscopic hysterectomy for benign diseases were investigated., Material and Methods: Macroscopic uterine parameters were determined during operation. First appearance of endometrium cells, complete disappearance of endometrial cells in the cervix and others were measured microscopically with reference to the external cervical orifice. Associations were described using odds ratio with 95% confidence interval and p-value <0.05., Results: The region of the cervix, in which exclusively cervical glands are found, is relatively small but varies considerably around the mean (mean, 23.3 mm, range, 10 to 35 mm). In this cohort in a remnant cervical stump of 23 mm length, endometrial glands would be found in 51%. There was no correlation between full cervical length and uterine parameters but smaller uteri tended to be associated with deeper endometrial penetration., Conclusion: There is a discrepancy between common definition and histological findings concerning the cervix uteri. Our findings indicate that the sacral uterine ligament is not suitable as an anatomic landmark for the laparoscopic supracervical hysterectomy operation. Regarding the distribution pattern of endometrial glands in the isthmic zone, a deep conical excision seems to better prevent subsequent spotting than a straight resection with thermocoagulation of the remaining cervical canal.
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- 2021
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18. Genital Prolapse Surgery: What Options Do We Have in the Age of Mesh Issues?
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Noé GK
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Here, we describe the current laparoscopic procedures for prolapse surgery and report data based on the application of these procedures. We also evaluate current approaches in vaginal prolapse surgery. Debates concerning the use of meshes have seriously affected vaginal surgery and threaten to influence reconstructive laparoscopic surgery as well. We describe the option of using autologous tissue in combination with the laparoscopic approach. Study data and problematic issues concerning the existing techniques are highlighted, and future options addressed.
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- 2021
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19. Prospective International Multicenter Pelvic Floor Study: Short-Term Follow-Up and Clinical Findings for Combined Pectopexy and Native Tissue Repair.
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Noé GK, Schiermeier S, Papathemelis T, Fuellers U, Khudyakovd A, Altmann HH, Borowski S, Morawski PP, Gantert M, De Vree B, Tkacz Z, Ugarteburu RG, and Anapolski M
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Efforts to use traditional native tissue strategies and reduce the use of meshes have been made in several countries. Combining native tissue repair with sufficient mesh applied apical repair might provide a means of effective treatment. The study group did perform and publish a randomized trial focusing on the combination of traditional native tissue repair with pectopexy or sacrocolpopexy and observed no severe or hitherto unknown risks for patients (Noé G.K. J Endourol 2015;29(2):210-5.). The short-term follow-up of this international multicenter study carried out now is presented in this article., Material and Methods: Eleven clinics and 13 surgeons in four European counties participated in the trial. In order to ensure a standardized approach and obtain comparable data, all surgeons were obliged to follow a standardized approach for pectopexy, focusing on the area of fixation and the use of a prefabricated mesh (PVDF PRP 3 × 15 Dynamesh). The mesh was solely used for apical repair. All other clinically relevant defects were treated with native tissue repair. Colposuspension or TVT were used for the treatment of incontinence. Data were collected independently for 14 months on a secured server; 501 surgeries were registered and evaluated. Two hundred and sixty-four patients out of 479 (55.1%) returned for the physical examination and interview after 12-18 months., Main Outcome and Results: The mean duration of follow-up was 15 months. The overall success of apical repair was rated positively by 96.9%, and the satisfaction score was rated positively by 95.5%. A positive general recommendation was expressed by 95.1% of patients. Pelvic pressure was reduced in 95.2%, pain in 98.0%, and urgency in 86.0% of patients. No major complications, mesh exposure, or mesh complication occurred during the follow-up period., Conclusion: In clinical routine, pectopexy and concomitant surgery, mainly using native tissue approaches, resulted in high satisfaction rates and favorable clinical findings. The procedure may also be recommended for use by general urogynecological practitioners with experience in laparoscopy.
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- 2021
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20. Prospective international multicenter pectopexy trial: Interim results and findings post surgery.
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Noé GK, Schiermeier S, Papathemelis T, Fuellers U, Khudyakov A, Altmann HH, Borowski S, Morawski PP, Gantert M, De Vree B, Zbigniew T, Ugarteburu RG, and Anapolski M
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- Europe epidemiology, Female, Humans, Operative Time, Postoperative Complications epidemiology, Prospective Studies, Gynecologic Surgical Procedures statistics & numerical data, Pelvic Organ Prolapse surgery
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The technique of laparoscopic pectopexy was published in 2010. A subsequent randomized trial focused on pectopexy versus sacropexy revealed no new risks for patients and significant advantages in terms of operating time and de novo defecation disorders compared to sacrocolpopexy. The present international multicenter trial was performed to evaluate the applicability of the technique in clinical routine., Material and Method: Eleven clinics and 13 surgeons in four European counties participated in the trial. To ensure a standardized approach and obtain comparable data, all surgeons followed the same rules in placing the apical tape, no further mesh was used. Data were collected for 14 months on a secured server; 501 surgeries were documented and evaluated., Results: Patients treated at the leading center (2 surgeons) contributed 44 % of the patient population. We made a distinction between high-volume (48-135 surgeries annually) (n = 4), intermediate-volume (28-37 surgeries annually) (n = 4), and low-volume (7-22 surgeries annually) (n = 5) surgeons. 97.3 % of the patients (n = 501) had delivered children; 5.6 % had had a Caesarian section. 29.7 % of the patients had undergone a hysterectomy. The operating time for pectopexy was less than 60 min in 79 % of cases. The procedures were completed in less than 159 min in 71 % of cases. Severe complications (n = 5) included four cases of organ damage (related to concomitant surgeries or adhesions) and one case of relevant bleeding. De novo incontinence was registered in two cases and voiding dysfunction in three. No intestinal obstruction or defecation disorder was observed. Two complicated infections were noted. Urinary infection occurred in 2 % of patients., Conclusion: In clinical routine severe complications occurred in 1 %. The latter were unrelated to pectopexy, but occurred due to concomitant procedures or adhesions. The overall operating time as well as the operating time for pectopexy were similar to those reported in published studies on sacrocolpopexy., (Copyright © 2019 Elsevier B.V. All rights reserved.)
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- 2020
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21. Laparoscopic anterior and posterior native tissue repair: a new pelvic floor approach.
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Noé GK, Alkatout I, Schiermeier S, Soltécz S, and Anapolski M
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- Aged, Aged, 80 and over, Female, Germany, Humans, Middle Aged, Surveys and Questionnaires, Treatment Outcome, Cystocele surgery, Laparoscopy methods, Pelvic Floor surgery, Pelvic Organ Prolapse surgery, Rectocele surgery, Uterine Prolapse surgery
- Abstract
Introduction: Traditionally, a cystocele caused by a midline defect of the pelvic fascia is treated by vaginal fascia duplication, also known as anterior colporraphy. The rectocele is managed by suturing the posterior fascia and, frequently, the levator ani muscles. We developed the approach of laparoscopic anterior and posterior fascia repair by native tissue. Material and methods: The methods were based on anterior and posterior exposure of pelvic fascia similar to the preparation of an extended sacral colpopexy. The fascia was compressed and narrowed by absorbable woven sutures, size 1. Twenty-seven patients were followed up for 6-13 months. All patients received additional apical fixation by pectopexy. Results: In the examination group, 13 patients underwent anterior laparoscopic fascia repair and 23 had posterior repair. We detected one apical and one posterior relapse, and also one in the anterior repair group. The patient with the apical relapse reported pain and de novo urgency. Anatomical reconstruction was achieved in all other patients. Summary: Laparoscopic anterior and posterior native tissue repair appears to be a feasible method for the treatment of midline cystocele and rectocele. No new risks were observed. The technique leaves no scar in the vagina and is well accepted. Abbreviations: POPQ: Pelvic Organ Prolapse Quantification System; FDA: Food and Drug Association; US: United States; Fig: Figure; ICIQ: International Consultation on Incontinence Questionnaire.
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- 2019
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22. Laparoscopic pectopexy: a follow-up cyclic biomechanical analysis determining time to functional stability.
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Sauerwald A, Langer L, Ratiu D, Prescher A, Scaal M, Noé GK, Wegmann K, Bulian DR, and Eichler C
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- Aged, 80 and over, Biomechanical Phenomena, Cadaver, Female, Follow-Up Studies, Humans, Laparoscopy methods, Pelvic Organ Prolapse surgery
- Abstract
Introduction: Pectopexy, a laparoscopic method for prolapse surgery, showed promising results in previous transient testing by this group. It was shown that a single suture, yielding an ultimate load of 35 N, was equivalent to continuous suturing. This was demonstrated in an in vitro cadaver study. This transient data were used to establish an elastic stress-strain envelope. It was now possible to proceed to dynamic in vitro analysis of this surgical method to establish time to functional stability., Methods: Cyclic testing of this fixation method was performed on human female embalmed cadaver (cohort 1) and fresh, non-embalmed cadaver (cohort 2) pelvises. The testing envelope was 5-25 N at a speed of 1 mm/s. 100 load regulated cycles were applied., Results: 100 cycles were completed with each model; no overall system failure occurred. Steady state, i.e., functional stability was reached after 14.5 (± 2.9) cycles for the embalmed group and after 19.1 (± 7.2) cycles for the non-embalmed group. This difference was statistically significant p = 0.00025., Conclusion: This trial showed in an in vitro cyclic testing of the pectopexy method that functional stability may be achieved after no more than 19.1 cycles of load exposure. When remaining within the established load envelope of below 25 N, patients do not need to fear global fixation failure. Testing did demonstrate differences in non-embalmed and embalmed cadaver testing. Embalmed cadaver testing tends to underestimate time to steady state by 26.3%.
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- 2019
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23. Laparoscopic Pectopexy: A Biomechanical Analysis.
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Sauerwald A, Niggl M, Puppe J, Prescher A, Scaal M, Noé GK, Schiermeier S, Warm M, and Eichler C
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- Aged, Biomechanical Phenomena, Cadaver, Female, Humans, Pelvic Organ Prolapse surgery, Surgical Mesh, Weight-Bearing, Laparoscopy methods, Ligaments surgery, Pelvis surgery, Suture Techniques
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Introduction: Pectopexy, a laparoscopic method for prolapse surgery, showed promising results in recent literature. Further improving this approach by reducing surgical time may decrease complication rates and patient morbidity. Since laparoscopic suturing is a time consuming task, we propose a single suture /mesh ileo-pectineal ligament fixation as opposed to the commonly used continues approach., Methods: Evaluation was performed on human non-embalmed, fresh cadaver pelves. A total of 33 trials was performed. Eight female pelves with an average age of 75, were used. This resulted in 16 available ligaments. Recorded parameters were ultimate load, displacement at failure and stiffness., Results: The ultimate load for the mesh + simplified single "interrupted" suture (MIS) group was 35 (± 12) N and 48 (± 7) N for the mesh + continuous suture (MCS) group. There was no significant difference in the ultimate load between both groups (p> 0.05). This was also true for displacement at failure measured at 37 (± 12) mm and 36 (±5) mm respectively. There was also no significant difference in stiffness and failure modes., Conclusion: Given the data above we must conclude that a continuous suture is not necessary in laparoscopic mesh / ileo-pectineal ligament fixation during pectopexy. Ultimate load and displacement at failure results clearly indicate that a single suture is not inferior to a continuous approach. The use of two single sutures may improve ligamental fixation. However, overall stability should not benefit since the surgical mesh remains the limiting factor.
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- 2016
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24. Abdominal anatomy in the context of port placement and trocars.
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Alkatout I, Mettler L, Maass N, Noé GK, and Elessawy M
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Although the anatomy of the human being has not changed, technical developments in operating materials and methods demand a simultaneous development in operative management. Developments in electronic and optical technologies permit many gynecological operations to be performed laparoscopically. One fundamental distinction between any other operating method and laparoscopy is the hurdle that the initial entry, whether with a needle, cannula, or trocar, is mostly performed blind. However, there is a risk that blind entry may result in vascular or organ damage. One of the difficulties associated with entry complications is that any damage may not be immediately recognized, leading to major abdominal reparative surgery, and at worst, a temporary colostomy. Therefore, the technical and operative quality of laparoscopic surgery begins with port placement and trocars. Visual access systems are available but are not yet widely used. The aim of this review was to introduce the different port placement and trocar systems as well as their correct and professional usage in correlation with the abdominal functional anatomy.
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- 2015
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25. Value of clinical and laboratory inflammation factors in the postoperative period after laparoscopic urogynecological surgery.
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Noé GK, Anapolski M, Soltész S, Spüntrup C, Mettler L, Schollmeyer T, and Alkatout I
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- Adult, Aged, Aged, 80 and over, C-Reactive Protein analysis, Female, Humans, Leukocyte Count, Middle Aged, ROC Curve, Retrospective Studies, Infections diagnosis, Inflammation diagnosis, Laparoscopy adverse effects, Postoperative Complications diagnosis, Urogenital Surgical Procedures adverse effects, Uterine Prolapse surgery
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Background/aims: Leukocytes and C-reactive protein (CRP) levels are often used to detect infections. The aim of this study was to evaluate the diagnostic and screening validity of leukocytes and CRP levels as well as body temperature >38° C to predict infections after laparoscopic sacrocolpopexy., Methods: The study included 287 patients suffering from genital prolapse higher than POP-Q I. In addition to the sacrocolpopexy, a laparoscopic supracervical hysterectomy was performed in cases of preexisting uterus (n = 171). Leukocytes and CRP levels were analyzed preoperatively and 4 days after surgery. Early and late onset of infections was documented., Results: Urinary tract infection was identified as the most frequent early postoperative complication (11.4%). Early wound infections were found in 2.8% of the patients (8/287). Late onset of infections was found in 1% of patients (3/287). Areas under ROC curves were low for both leukocytes (0.52, 95% CI: 0.37-0.66) and CRP levels (0.60, 95% CI: 0.44-0.77)., Conclusion: Our findings question the benefit of routine determination of leukocytes and CRP levels 4 days after surgery. The sensitivity and specificity of leukocytes and CRP levels are probably more significant after normalization of the initial tissue response (days 8-10)., (© 2014 S. Karger AG, Basel.)
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- 2015
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26. Pain medication requirements after sacropexy and combination interventions.
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Noé GK, Schiermeier S, Hatzmann W, Soltész S, Spüntrup C, and Anapolski M
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- Abdominal Pain etiology, Adult, Aged, Aged, 80 and over, Female, Humans, Male, Middle Aged, Pain, Postoperative etiology, Treatment Outcome, Abdominal Pain drug therapy, Analgesics therapeutic use, Laparoscopy adverse effects, Pain Management methods, Pain, Postoperative drug therapy, Pelvic Organ Prolapse surgery
- Abstract
Background and Objectives: Laparoscopic surgery is associated with reduced morbidity, and postoperative pain is reduced. The aim of this study was to assess postoperative pain intensity, analgesic requirements, and the influence of cofactors after laparoscopic sacral colpopexy., Methods: The study assessed 287 patients treated with laparoscopic sacropexy for genital prolapse with a Pelvic Organ Prolapse Quantification grade>1. Patients were asked to evaluate their pain postoperatively using a 4-point verbal pain rating scale. In addition, medical records were analyzed regarding the requirement for analgesic medication., Results: Patients distinguished between abdominal pain and shoulder pain after laparoscopy. Abdominal pain reached maximum severity on day 1 and showed a good response to nonsteroidal antiphlogistics, whereas shoulder pain was rarely found (6.27%). Of the patients, 38% required no pain treatment or required 1 dose at most. The need for pain medication reached its climax on day 1 and decreased during the 5 following days. Non-opioid analgesics provided a sufficient therapeutic effect., Conclusion: Laparoscopic sacropexy is associated with a moderate degree of postoperative pain. Non-opioid analgesics should be preferred as first-line therapy. The typical shoulder-tip pain showed only a low prevalence in our study group. From our point of view, the low rate of shoulder-tip pain corresponded with the low intra-abdominal carbon dioxide pressure.
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- 2014
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27. The German version of the 'ICIQ Vaginal Symptoms Questionnaire' (German ICIQ-VS): an instrument validation study.
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Banerjee C, Banerjee M, Hatzmann W, Schiermeier S, Sachse K, Hellmich M, and Noé GK
- Subjects
- Adult, Aged, Case-Control Studies, Comprehension, Cultural Characteristics, Female, Germany, Humans, Language, Middle Aged, Observer Variation, Pelvic Organ Prolapse complications, Pelvic Organ Prolapse psychology, Pilot Projects, Predictive Value of Tests, Quality of Life, Reproducibility of Results, Sensitivity and Specificity, Severity of Illness Index, Vaginal Diseases etiology, Vaginal Diseases psychology, Pelvic Organ Prolapse diagnosis, Psychometrics, Surveys and Questionnaires, Vaginal Diseases diagnosis
- Abstract
Introduction: No validated questionnaire that evaluates vaginal symptoms is currently available in the German language. Here, we report the translation and validation process of the German ICIQ-VS., Subjects: Pilot study: 10 patients without any specific disease. MAIN STUDY: 58 Patients (cases) suffering from genital descensus higher than grade 1 pelvic organ prolapse quantification (POPQ) and 51 patients (controls) without vaginal affections., Methods: To establish a cultural-adaptive equivalent in German, recommendations from Guillemin et al. [J Clin Epidemiol 1993;46:1417-1432] were carefully followed. Participants of the main study were asked to fill in the questionnaire at three time points [baseline (T1), 7 days later (T2) and 1 year later (T3)]. Reliability, validity and sensitivity to change were evaluated., Results: In our pilot study, all questionnaire items were correctly interpreted and answered. In the main study, no changes from the original format were observed after translation and cultural adaptation. For the cases, internal consistency was acceptable (Cronbach's alpha 0.72-0.79) and test-retest reliability was moderate to near-perfect for single items (weighted kappa 0.67-0.94). Sensitivity to change and content validity were excellent. Construct validity revealed statistically significant differences between groups., Conclusion: The ICIQ-VS has successfully been translated and validated into the German language., (Copyright (c) 2010 S. Karger AG, Basel.)
- Published
- 2010
- Full Text
- View/download PDF
28. Sexual impairment in women undergoing laparoscopic surgery for genital prolapse: a hospital-based cohort study.
- Author
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Banerjee C, Sachse K, Hellmich M, Fanselau C, Banerjee M, and Noé GK
- Subjects
- Adult, Aged, Cohort Studies, Female, Germany, Hospitals, Humans, Middle Aged, Pelvic Organ Prolapse complications, Pelvic Organ Prolapse psychology, Retrospective Studies, Sexual Dysfunction, Physiological psychology, Sexual Dysfunctions, Psychological psychology, Surveys and Questionnaires, Treatment Outcome, Laparoscopy adverse effects, Pelvic Organ Prolapse surgery, Sexual Dysfunction, Physiological etiology, Sexual Dysfunctions, Psychological etiology, Sexuality
- Abstract
Introduction: No data regarding sexuality following laparoscopic prolapse surgery are available to date. Our hypothesis is that laparoscopic sacropexy does not influence sexuality negatively, whereas concomitant (vaginal) surgery negatively influences sexuality., Methods: Participants were 132 patients who underwent laparoscopic sacropexy. We compared pre- and postoperative sexual scores by 2 validated questionnaires., Results: The response rate was 84% (111/132). No change in sexual activity was reported after surgery. In the sexually active group (56.8%; 63/111) the impairment of sexuality was significantly reduced in all age groups independently of concomitant vaginal surgery. In the sexually inactive group, only 4.3% (2/48) were inactive because of vaginal symptoms before operation. After the operation these patients stayed inactive; however, 1 reported reasons unrelated to prolapse., Conclusions: Laparoscopic prolapse surgery reduces sexual impairment in sexually active patients. There appears to be no benefit for patients who are not sexually active for reasons related to the prolapse. Concomitant surgery does not affect sexual activity., (Copyright © 2010 S. Karger AG, Basel.)
- Published
- 2010
- Full Text
- View/download PDF
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